2BXIA

Human serum albumin complexed with myristate and azapropazone
Total Genus 218
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKEEQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 218
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxiA05
1BM0A 3JQZA 2BXLA 2BXGA 4ZBRA 4ZBQA 5DQFA 4LB9A 4HGKA 4G04A 2BXAA 3TDLA 2BXHA 1MA9A 3A73A 1HK3A 4N0FD 2XVWA 3B9LA 1HK1A 1E7EA 4PO0A 5HOZA 1J7EA 2BXQA 3LU8A 1LOTA 1E7BA 2XW0A 4N0UD 5IIXA 1GNJA 3V09A 4BKEA 4F5VA 1E7IA 1HA2A 4IW1A 5GHKA 4E99A 2I30A 5DBYA 1J78A 5IJEA 4LUFA 1AO6A 4OR0A 3SQJA 2BXFA 3V08A 4LA0A 2VUFA 2BXCA 5IJ5A 4Z69A 1E7AA 4K71A 4L9QA 2BXPA 2BXIA 3LU7A 2VUEA 2XSIA 2BXMA 4K2CA 4IW2A 2BXKA 4G03A 1HK5A 4F5SA 1BJ5A 4L9KA 2BXDA 1KW2A 1KXPD 1E7FA 1N5UA 3LU6A 2YDFA 2BXBA 5ID9A 2I2ZA 4LB2A 2VDBA 2XVUA 2BXEA 3B9MA 1E7GA 4EMXA 5FUOA 3UIVA 2XVVA 1E78A 1HK2A 3CX9A 3JRYA 1E7CA 4HGMB 1E7HA 5ID7A 1HK4A 1TF0A 4JK4A 4LUHA 2BX8A 4S1YA 2XW1A 5IIHA 2XVQA 1GNIA 1UORA 5IFOA 4F5UA 2BXNA 5IIUA 2BXOA 5IJFA 1O9XA 1BKEA 1H9ZA 4L8UA 3V03A 4J2VA 4OT2A 4F5TA
chains in the Genus database with same CATH superfamily
3NMUA 1BM0A 1JNBA 2QM6A 2V36A 4DHXB 5BPKA 3JQZA 2BXLA 2BXGA 3MHSB 4ZBRA 3NVIA 2KWFA 2DG5A 2EFEA 2DBXA 4M70B 5DQFA 2EFHA 4ZBQA 4LB9A 1KDXA 4HGKA 4G04A 1MUSA 2BXAA 3TDLA 2BXHA 2XMOA 1MA9A 3A73A 4GG2A 1HK3A 4N0FD 4DM0A 2XVWA 2Z8JA 5GIPA 2EFDA 3B9LA 1HK1A 2E0YA 1LNSA 3VQIA 3H3AA 4FIPB 2Z8IA 1E7EA 4PO0A 4NAWB 5HOZA 3M99C 2LXSA 1J7EA 5GIOA 1TXUA 3FNMA 4FJCB 4G01A 3GQUA 2BXQA 3LU8A 1LOTA 4BY9C 2AGHB 1E7BA 3WHQA 4ZBKA 3H37A 2XW0A 3ICXA 3WHSA 2AJEA 3BPJA 4N0UD 5IIXA 3NVMA 4GDLB 1GNJA 2Z8KA 3V09A 4BKEA 4F5VA 1E7IA 1HA2A 4IW1A 3PLAA 2OZBB 5GHKA 4E99A 2QMCA 2I30A 5DBYA 1J78A 5IJEA 3A75A 4LUFA 2OT3A 1AO6A 3FWBC 4OR0A 3SQJA 2BXFA 3V08A 4LA0A 1IJGA 2CKXA 2VUFA 3SIUB 2BXCA 1H5WA 2LOQA 5IJ5A 2DBUA 4Z69A 1E7AA 4GDKB 4K71A 4L9QA 3WHRA 2BXPA 3GA9L 2BXIA 3LU7A 1VFIA 4Z9OA 2NQOA 2VUEA 2XSIA 2BXMA 4ZC6A 4K2CA 2GUTA 2EFCA 4IW2A 2BXKA 4G03A 1HK5A 4F5SA 1BJ5A 4L9KA 2BXDA 1KW2A 1KXPD 2DYMA 1E7FA 1N5UA 2KBZA 3LU6A 2YDFA 2BXBA 5ID9A 4TQ0A 1FOUA 1MIWA 2DYOA 5D7GA 4GDXA 1NT2B 1SB0A 2I2ZA 2LXTA 4LB2A 2VDBA 4C31B 1MUHA 2XVUA 2BXEA 3G9KD 3GQXA 2LQIA 3B9MA 5B5TA 1E7GA 1MIVA 4EMXA 5FUOA 1VZSA 2XVVA 3UIVA 1E78A 1HK2A 3CX9A 4FK5B 3JRYA 1E7CA 4ZCGA 4HGMB 4OTTA 1MM8A 2E0XA 4I9OA 1MIYA 1E7HA 2QHBA 2ROHA 4OTUA 4WA6B 5ID7A 3KJLA 1HK4A 1TF0A 4JK4A 3ECPA 4LUHA 4TQ1A 2BX8A 2JUHA 4S1YA 3MHHB 3FWCC 2XW1A 4W4UB 5IIHA 2XVQA 1GNIA 1UORA 5IFOA 4F5UA 5GINA 2DBWA 4MBEC 2LQHA 2NNWA 4D7XA 2BXNA 5IIUA 2BXOA 5IJFA 1O9XA 1BKEA 3NVKA 3SIVB 1H9ZA 4L8UA 3V03A 3W1SA 4N3ZA 4J2VA 4OT2A 4ZUXV 2K0NA 4F5TA 3KIKA
chains in the Genus database with same CATH topology
3NMUA 1BM0A 1JNBA 2QM6A 2V36A 4DHXB 5BPKA 3JQZA 2BXLA 2BXGA 3MHSB 4ZBRA 3NVIA 4M70B 2DG5A 2EFEA 2DBXA 5DQFA 4ZBQA 2EFHA 4LB9A 4HGKA 4G04A 2BXAA 3TDLA 2BXHA 2XMOA 1MA9A 3A73A 4GG2A 1HK3A 4N0FD 2XVWA 2Z8JA 5GIPA 2EFDA 3B9LA 1HK1A 2E0YA 1LNSA 3VQIA 3H3AA 4FIPB 2Z8IA 1E7EA 4PO0A 4NAWB 5HOZA 3M99C 1J7EA 5GIOA 1TXUA 3FNMA 4FJCB 4G01A 3GQUA 2BXQA 3LU8A 1LOTA 4BY9C 1E7BA 3WHQA 4ZBKA 3H37A 2XW0A 3ICXA 3WHSA 2AJEA 4N0UD 5IIXA 3NVMA 4GDLB 1GNJA 2Z8KA 3V09A 4BKEA 4F5VA 1E7IA 1HA2A 4IW1A 3PLAA 2OZBB 5GHKA 4E99A 2QMCA 2I30A 5DBYA 1J78A 5IJEA 3A75A 4LUFA 2OT3A 1AO6A 3FWBC 4OR0A 3SQJA 2BXFA 3V08A 4LA0A 1IJGA 2CKXA 2VUFA 3SIUB 2BXCA 1H5WA 2LOQA 5IJ5A 2DBUA 4Z69A 1E7AA 4GDKB 4K71A 4L9QA 3WHRA 2BXPA 3GA9L 2BXIA 3LU7A 1VFIA 4Z9OA 2NQOA 2VUEA 2XSIA 2BXMA 4ZC6A 4K2CA 2EFCA 4IW2A 2BXKA 4G03A 1HK5A 4F5SA 1BJ5A 4L9KA 2BXDA 1KW2A 1KXPD 2DYMA 1E7FA 1N5UA 2KBZA 3LU6A 2YDFA 2BXBA 5ID9A 4TQ0A 1FOUA 1MIWA 2DYOA 5D7GA 4GDXA 1NT2B 2I2ZA 4LB2A 2VDBA 4C31B 2XVUA 2BXEA 3G9KD 3GQXA 3B9MA 5B5TA 1E7GA 1MIVA 4EMXA 5FUOA 1VZSA 2XVVA 3UIVA 1E78A 1HK2A 3CX9A 4FK5B 3JRYA 1E7CA 4ZCGA 4HGMB 4OTTA 2E0XA 1MIYA 1E7HA 2QHBA 2ROHA 4OTUA 4WA6B 5ID7A 3KJLA 1HK4A 1TF0A 4JK4A 4LUHA 4TQ1A 2BX8A 2JUHA 4S1YA 3MHHB 3FWCC 2XW1A 4W4UB 5IIHA 2XVQA 1GNIA 1UORA 5IFOA 4F5UA 5GINA 2DBWA 4MBEC 2NNWA 2BXNA 5IIUA 2BXOA 5IJFA 1O9XA 1BKEA 3NVKA 3SIVB 1H9ZA 4L8UA 3V03A 3W1SA 4N3ZA 4J2VA 4OT2A 4ZUXV 4F5TA 3KIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BM0 A;  3JQZ A;  2BXL A;  2BXG A;  4ZBR A;  4ZBQ A;  5DQF A;  4LB9 A;  4HGK A;  4G04 A;  2BXA A;  3TDL A;  2BXH A;  1MA9 A;  3A73 A;  1HK3 A;  4N0F D;  2XVW A;  3B9L A;  1HK1 A;  1E7E A;  4PO0 A;  5HOZ A;  1J7E A;  2BXQ A;  3LU8 A;  1LOT A;  1E7B A;  2XW0 A;  4N0U D;  5IIX A;  1GNJ A;  3V09 A;  4BKE A;  4F5V A;  1E7I A;  1HA2 A;  4IW1 A;  5GHK A;  4E99 A;  2I30 A;  5DBY A;  1J78 A;  5IJE A;  4LUF A;  1AO6 A;  4OR0 A;  3SQJ A;  2BXF A;  3V08 A;  4LA0 A;  2VUF A;  2BXC A;  5IJ5 A;  4Z69 A;  1E7A A;  4K71 A;  4L9Q A;  2BXP A;  2BXI A;  3LU7 A;  2VUE A;  2XSI A;  2BXM A;  4K2C A;  4IW2 A;  2BXK A;  4G03 A;  1HK5 A;  4F5S A;  1BJ5 A;  4L9K A;  2BXD A;  1KW2 A;  1KXP D;  1E7F A;  1N5U A;  3LU6 A;  2YDF A;  2BXB A;  5ID9 A;  2I2Z A;  4LB2 A;  2VDB A;  2XVU A;  2BXE A;  3B9M A;  1E7G A;  4EMX A;  5FUO A;  3UIV A;  2XVV A;  1E78 A;  1HK2 A;  3CX9 A;  3JRY A;  1E7C A;  4HGM B;  1E7H A;  5ID7 A;  1HK4 A;  1TF0 A;  4JK4 A;  4LUH A;  2BX8 A;  4S1Y A;  2XW1 A;  5IIH A;  2XVQ A;  1GNI A;  1UOR A;  5IFO A;  4F5U A;  2BXN A;  5IIU A;  2BXO A;  5IJF A;  1O9X A;  1BKE A;  1H9Z A;  4L8U A;  3V03 A;  4J2V A;  4OT2 A;  4F5T A; 
#chains in the Genus database with same CATH topology
 3NMU A;  1BM0 A;  1JNB A;  2QM6 A;  2V36 A;  4DHX B;  5BPK A;  3JQZ A;  2BXL A;  2BXG A;  3MHS B;  4ZBR A;  3NVI A;  2KWF A;  2DG5 A;  2EFE A;  2DBX A;  4M70 B;  5DQF A;  2EFH A;  4ZBQ A;  4LB9 A;  1KDX A;  4HGK A;  4G04 A;  1MUS A;  2BXA A;  3TDL A;  2BXH A;  2XMO A;  1MA9 A;  3A73 A;  4GG2 A;  1HK3 A;  4N0F D;  4DM0 A;  2XVW A;  2Z8J A;  5GIP A;  2EFD A;  3B9L A;  1HK1 A;  2E0Y A;  1LNS A;  3VQI A;  3H3A A;  4FIP B;  2Z8I A;  1E7E A;  4PO0 A;  4NAW B;  5HOZ A;  3M99 C;  2LXS A;  1J7E A;  5GIO A;  1TXU A;  3FNM A;  4FJC B;  4G01 A;  3GQU A;  2BXQ A;  3LU8 A;  1LOT A;  4BY9 C;  2AGH B;  1E7B A;  3WHQ A;  4ZBK A;  3H37 A;  2XW0 A;  3ICX A;  3WHS A;  2AJE A;  3BPJ A;  4N0U D;  5IIX A;  3NVM A;  4GDL B;  1GNJ A;  2Z8K A;  3V09 A;  4BKE A;  4F5V A;  1E7I A;  1HA2 A;  4IW1 A;  3PLA A;  2OZB B;  5GHK A;  4E99 A;  2QMC A;  2I30 A;  5DBY A;  1J78 A;  5IJE A;  3A75 A;  4LUF A;  2OT3 A;  1AO6 A;  3FWB C;  4OR0 A;  3SQJ A;  2BXF A;  3V08 A;  4LA0 A;  1IJG A;  2CKX A;  2VUF A;  3SIU B;  2BXC A;  1H5W A;  2LOQ A;  5IJ5 A;  2DBU A;  4Z69 A;  1E7A A;  4GDK B;  4K71 A;  4L9Q A;  3WHR A;  2BXP A;  3GA9 L;  2BXI A;  3LU7 A;  1VFI A;  4Z9O A;  2NQO A;  2VUE A;  2XSI A;  2BXM A;  4ZC6 A;  4K2C A;  2GUT A;  2EFC A;  4IW2 A;  2BXK A;  4G03 A;  1HK5 A;  4F5S A;  1BJ5 A;  4L9K A;  2BXD A;  1KW2 A;  1KXP D;  2DYM A;  1E7F A;  1N5U A;  2KBZ A;  3LU6 A;  2YDF A;  2BXB A;  5ID9 A;  4TQ0 A;  1FOU A;  1MIW A;  2DYO A;  5D7G A;  4GDX A;  1NT2 B;  1SB0 A;  2I2Z A;  2LXT A;  4LB2 A;  2VDB A;  4C31 B;  1MUH A;  2XVU A;  2BXE A;  3G9K D;  3GQX A;  2LQI A;  3B9M A;  5B5T A;  1E7G A;  1MIV A;  4EMX A;  5FUO A;  1VZS A;  2XVV A;  3UIV A;  1E78 A;  1HK2 A;  3CX9 A;  4FK5 B;  3JRY A;  1E7C A;  4ZCG A;  4HGM B;  4OTT A;  1MM8 A;  2E0X A;  4I9O A;  1MIY A;  1E7H A;  2QHB A;  2ROH A;  4OTU A;  4WA6 B;  5ID7 A;  3KJL A;  1HK4 A;  1TF0 A;  4JK4 A;  3ECP A;  4LUH A;  4TQ1 A;  2BX8 A;  2JUH A;  4S1Y A;  3MHH B;  3FWC C;  2XW1 A;  4W4U B;  5IIH A;  2XVQ A;  1GNI A;  1UOR A;  5IFO A;  4F5U A;  5GIN A;  2DBW A;  4MBE C;  2LQH A;  2NNW A;  4D7X A;  2BXN A;  5IIU A;  2BXO A;  5IJF A;  1O9X A;  1BKE A;  3NVK A;  3SIV B;  1H9Z A;  4L8U A;  3V03 A;  3W1S A;  4N3Z A;  4J2V A;  4OT2 A;  4ZUX V;  2K0N A;  4F5T A;  3KIK A; 
#chains in the Genus database with same CATH homology
 3NMU A;  1BM0 A;  1JNB A;  2QM6 A;  2V36 A;  4DHX B;  5BPK A;  3JQZ A;  2BXL A;  2BXG A;  3MHS B;  4ZBR A;  3NVI A;  4M70 B;  2DG5 A;  2EFE A;  2DBX A;  5DQF A;  4ZBQ A;  2EFH A;  4LB9 A;  4HGK A;  4G04 A;  2BXA A;  3TDL A;  2BXH A;  2XMO A;  1MA9 A;  3A73 A;  4GG2 A;  1HK3 A;  4N0F D;  2XVW A;  2Z8J A;  5GIP A;  2EFD A;  3B9L A;  1HK1 A;  2E0Y A;  1LNS A;  3VQI A;  3H3A A;  4FIP B;  2Z8I A;  1E7E A;  4PO0 A;  4NAW B;  5HOZ A;  3M99 C;  1J7E A;  5GIO A;  1TXU A;  3FNM A;  4FJC B;  4G01 A;  3GQU A;  2BXQ A;  3LU8 A;  1LOT A;  4BY9 C;  1E7B A;  3WHQ A;  4ZBK A;  3H37 A;  2XW0 A;  3ICX A;  3WHS A;  2AJE A;  4N0U D;  5IIX A;  3NVM A;  4GDL B;  1GNJ A;  2Z8K A;  3V09 A;  4BKE A;  4F5V A;  1E7I A;  1HA2 A;  4IW1 A;  3PLA A;  2OZB B;  5GHK A;  4E99 A;  2QMC A;  2I30 A;  5DBY A;  1J78 A;  5IJE A;  3A75 A;  4LUF A;  2OT3 A;  1AO6 A;  3FWB C;  4OR0 A;  3SQJ A;  2BXF A;  3V08 A;  4LA0 A;  1IJG A;  2CKX A;  2VUF A;  3SIU B;  2BXC A;  1H5W A;  2LOQ A;  5IJ5 A;  2DBU A;  4Z69 A;  1E7A A;  4GDK B;  4K71 A;  4L9Q A;  3WHR A;  2BXP A;  3GA9 L;  2BXI A;  3LU7 A;  1VFI A;  4Z9O A;  2NQO A;  2VUE A;  2XSI A;  2BXM A;  4ZC6 A;  4K2C A;  2EFC A;  4IW2 A;  2BXK A;  4G03 A;  1HK5 A;  4F5S A;  1BJ5 A;  4L9K A;  2BXD A;  1KW2 A;  1KXP D;  2DYM A;  1E7F A;  1N5U A;  2KBZ A;  3LU6 A;  2YDF A;  2BXB A;  5ID9 A;  4TQ0 A;  1FOU A;  1MIW A;  2DYO A;  5D7G A;  4GDX A;  1NT2 B;  2I2Z A;  4LB2 A;  2VDB A;  4C31 B;  2XVU A;  2BXE A;  3G9K D;  3GQX A;  3B9M A;  5B5T A;  1E7G A;  1MIV A;  4EMX A;  5FUO A;  1VZS A;  2XVV A;  3UIV A;  1E78 A;  1HK2 A;  3CX9 A;  4FK5 B;  3JRY A;  1E7C A;  4ZCG A;  4HGM B;  4OTT A;  2E0X A;  1MIY A;  1E7H A;  2QHB A;  2ROH A;  4OTU A;  4WA6 B;  5ID7 A;  3KJL A;  1HK4 A;  1TF0 A;  4JK4 A;  4LUH A;  4TQ1 A;  2BX8 A;  2JUH A;  4S1Y A;  3MHH B;  3FWC C;  2XW1 A;  4W4U B;  5IIH A;  2XVQ A;  1GNI A;  1UOR A;  5IFO A;  4F5U A;  5GIN A;  2DBW A;  4MBE C;  2NNW A;  2BXN A;  5IIU A;  2BXO A;  5IJF A;  1O9X A;  1BKE A;  3NVK A;  3SIV B;  1H9Z A;  4L8U A;  3V03 A;  3W1S A;  4N3Z A;  4J2V A;  4OT2 A;  4ZUX V;  4F5T A;  3KIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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