2BXKA

Human serum albumin complexed with myristate, azapropazone and indomethacin
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKEEQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 226
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxkA05
2BXGA 3LU8A 2BXPA 2BXDA 4L8UA 1GNJA 2XW1A 2XVUA 4K2CA 3A73A 1HK3A 2VUFA 3JQZA 2XVQA 2BXCA 2I2ZA 4L9QA 2BXHA 5IIUA 1E7BA 1J78A 1J7EA 2VUEA 5FUOA 1E7GA 1BKEA 4ZBRA 1H9ZA 1LOTA 2XSIA 1BM0A 4LB9A 1O9XA 5DQFA 4IW2A 4LA0A 4LB2A 4F5VA 2YDFA 1GNIA 2BXOA 2I30A 1N5UA 4Z69A 4ZBQA 5IIXA 2BXIA 4LUHA 5DBYA 1E7AA 5GHKA 2BXKA 5IJEA 4S1YA 4HGKA 3V08A 4F5UA 3UIVA 3V03A 1TF0A 2BXQA 2XW0A 1HK4A 4OT2A 4PO0A 1HA2A 3SQJA 4F5SA 4EMXA 2BXFA 3V09A 2BXLA 1E7CA 1E7IA 5IJFA 4L9KA 1E7FA 1HK2A 5IJ5A 4N0UD 1HK5A 3CX9A 4JK4A 4J2VA 1AO6A 4BKEA 1KW2A 4HGMB 3TDLA 1KXPD 5HOZA 4E99A 3LU6A 4G03A 1E78A 2XVWA 4OR0A 3B9LA 2BXEA 5IIHA 2BXMA 1E7EA 5IFOA 4F5TA 3LU7A 1UORA 3JRYA 1MA9A 2VDBA 1E7HA 4N0FD 2BXAA 2XVVA 4K71A 2BX8A 2BXNA 4IW1A 5ID7A 2BXBA 1HK1A 4LUFA 4G04A 3B9MA 1BJ5A 5ID9A
chains in the Genus database with same CATH superfamily
4ZCGA 2BXGA 5BPKA 3LU8A 3PLAA 2BXPA 2BXDA 3G9KD 4FIPB 4L8UA 1FOUA 4TQ1A 2V36A 1GNJA 2XW1A 2XVUA 4K2CA 3A73A 3NMUA 1HK3A 2VUFA 1H5WA 3JQZA 4I9OA 2LQHA 2BXCA 2I2ZA 2XVQA 3H37A 2BXHA 4L9QA 5IIUA 2K0NA 1E7BA 4OTTA 4MBEC 3MHHB 2DYOA 4FJCB 1J78A 1J7EA 2JUHA 2VUEA 1LNSA 5FUOA 1E7GA 4Z9OA 1BKEA 3NVIA 4ZBRA 1H9ZA 1LOTA 2XSIA 1BM0A 2Z8JA 4LB9A 5D7GA 2QMCA 3WHSA 4FK5B 1O9XA 1TXUA 4N3ZA 2KWFA 4IW2A 5DQFA 2Z8IA 4LA0A 4LB2A 4GDXA 5GIPA 2OT3A 4F5VA 2YDFA 1GNIA 2BXOA 2I30A 2LQIA 2DBWA 1N5UA 3B9MA 3M99C 5GIOA 4DM0A 1MUSA 4Z69A 4ZBQA 5IIXA 1MIWA 1VZSA 2BXIA 5GINA 2DBXA 3FNMA 3BPJA 4LUHA 4W4UB 2GUTA 2DBUA 5DBYA 2LXTA 1E7AA 2NNWA 5GHKA 4DHXB 3A75A 2BXKA 2E0XA 3GA9L 5IJEA 1MM8A 4S1YA 4HGKA 3V08A 4F5UA 3UIVA 3V03A 1TF0A 2BXQA 2XW0A 3NVKA 4G04A 2CKXA 1HK4A 4OT2A 4PO0A 1HA2A 3GQUA 3W1SA 3SQJA 4F5SA 1MIYA 4EMXA 2BXFA 3V09A 4ZC6A 4ZUXV 2BXLA 1E7CA 1VFIA 1E7IA 2EFHA 2LOQA 5IJFA 1MIVA 2EFCA 4L9KA 4C31B 1E7FA 1HK2A 2EFDA 3ECPA 2ROHA 5IJ5A 4N0UD 1HK5A 2XMOA 2DG5A 3CX9A 4JK4A 2EFEA 4J2VA 1AO6A 3MHSB 3ICXA 1KW2A 4BKEA 4HGMB 4G01A 4WA6B 3TDLA 1KXPD 4ZBKA 5HOZA 4E99A 3FWCC 1IJGA 3LU6A 3KIKA 1E78A 2XVWA 3H3AA 3NVMA 4G03A 4OR0A 3B9LA 2OZBB 2BXEA 5IIHA 4NAWB 3GQXA 1JNBA 2BXMA 1E7EA 3WHRA 5IFOA 4F5TA 3LU7A 2DYMA 1UORA 3JRYA 1MA9A 3SIUB 2VDBA 3KJLA 1SB0A 4GDKB 2QM6A 1E7HA 4GDLB 1MUHA 4D7XA 3FWBC 4N0FD 2BXAA 2XVVA 4K71A 3VQIA 2QHBA 4BY9C 2E0YA 2BX8A 2AJEA 2AGHB 2BXNA 5B5TA 1NT2B 4GG2A 4IW1A 5ID7A 3SIVB 2BXBA 4OTUA 4M70B 3WHQA 2Z8KA 2KBZA 4TQ0A 1HK1A 1KDXA 4LUFA 2LXSA 2NQOA 1BJ5A 5ID9A
chains in the Genus database with same CATH topology
4ZCGA 2BXGA 5BPKA 3LU8A 3PLAA 2BXPA 2BXDA 3G9KD 4FIPB 4L8UA 1FOUA 4TQ1A 2V36A 1GNJA 2XW1A 2XVUA 4K2CA 3A73A 3NMUA 1HK3A 1H5WA 3JQZA 2XVQA 2BXCA 2I2ZA 3H37A 4L9QA 2BXHA 5IIUA 1E7BA 4OTTA 4MBEC 3MHHB 2DYOA 4FJCB 1J78A 1J7EA 2JUHA 2VUEA 1LNSA 5FUOA 1E7GA 4Z9OA 1BKEA 3NVIA 4ZBRA 1H9ZA 1LOTA 2XSIA 1BM0A 2Z8JA 4LB9A 5D7GA 2QMCA 3WHSA 4FK5B 1O9XA 1TXUA 4N3ZA 5DQFA 4IW2A 2Z8IA 4LA0A 4LB2A 4GDXA 5GIPA 2OT3A 4F5VA 2YDFA 1GNIA 2BXOA 2I30A 2DBWA 1N5UA 3B9MA 3M99C 5GIOA 4Z69A 4ZBQA 5IIXA 1MIWA 1VZSA 2BXIA 5GINA 2DBXA 3FNMA 4LUHA 4W4UB 2DBUA 5DBYA 1E7AA 2NNWA 5GHKA 4DHXB 3A75A 2BXKA 2E0XA 3GA9L 5IJEA 4S1YA 4HGKA 3V08A 4F5UA 3UIVA 3V03A 1TF0A 2BXQA 2XW0A 3NVKA 4G04A 2CKXA 1HK4A 4OT2A 4PO0A 1HA2A 3GQUA 3W1SA 3SQJA 4F5SA 1MIYA 4EMXA 2BXFA 3V09A 4ZC6A 4ZUXV 2BXLA 1E7CA 1VFIA 1E7IA 2EFHA 2LOQA 5IJFA 1MIVA 2EFCA 4L9KA 4C31B 1E7FA 1HK2A 2EFDA 2ROHA 5IJ5A 4N0UD 1HK5A 2XMOA 2DG5A 3CX9A 4JK4A 2EFEA 4J2VA 1AO6A 3MHSB 3ICXA 1KW2A 4BKEA 4HGMB 4G01A 4WA6B 3TDLA 1KXPD 4ZBKA 5HOZA 4E99A 3FWCC 1IJGA 3LU6A 3KIKA 1E78A 2XVWA 3H3AA 3NVMA 4G03A 4OR0A 3B9LA 2OZBB 2BXEA 5IIHA 4NAWB 3GQXA 1JNBA 2BXMA 1E7EA 3WHRA 5IFOA 4F5TA 3LU7A 2DYMA 1UORA 3JRYA 1MA9A 3SIUB 2VDBA 3KJLA 4GDKB 2QM6A 1E7HA 4GDLB 3FWBC 4N0FD 2BXAA 2XVVA 4K71A 3VQIA 2QHBA 4BY9C 2E0YA 2BX8A 2AJEA 2BXNA 5B5TA 1NT2B 4GG2A 4IW1A 5ID7A 3SIVB 2BXBA 4OTUA 4M70B 3WHQA 2Z8KA 2KBZA 4TQ0A 1HK1A 4LUFA 2VUFA 2NQOA 1BJ5A 5ID9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXG A;  3LU8 A;  2BXP A;  2BXD A;  4L8U A;  1GNJ A;  2XW1 A;  2XVU A;  4K2C A;  3A73 A;  1HK3 A;  2VUF A;  3JQZ A;  2XVQ A;  2BXC A;  2I2Z A;  4L9Q A;  2BXH A;  5IIU A;  1E7B A;  1J78 A;  1J7E A;  2VUE A;  5FUO A;  1E7G A;  1BKE A;  4ZBR A;  1H9Z A;  1LOT A;  2XSI A;  1BM0 A;  4LB9 A;  1O9X A;  5DQF A;  4IW2 A;  4LA0 A;  4LB2 A;  4F5V A;  2YDF A;  1GNI A;  2BXO A;  2I30 A;  1N5U A;  4Z69 A;  4ZBQ A;  5IIX A;  2BXI A;  4LUH A;  5DBY A;  1E7A A;  5GHK A;  2BXK A;  5IJE A;  4S1Y A;  4HGK A;  3V08 A;  4F5U A;  3UIV A;  3V03 A;  1TF0 A;  2BXQ A;  2XW0 A;  1HK4 A;  4OT2 A;  4PO0 A;  1HA2 A;  3SQJ A;  4F5S A;  4EMX A;  2BXF A;  3V09 A;  2BXL A;  1E7C A;  1E7I A;  5IJF A;  4L9K A;  1E7F A;  1HK2 A;  5IJ5 A;  4N0U D;  1HK5 A;  3CX9 A;  4JK4 A;  4J2V A;  1AO6 A;  4BKE A;  1KW2 A;  4HGM B;  3TDL A;  1KXP D;  5HOZ A;  4E99 A;  3LU6 A;  4G03 A;  1E78 A;  2XVW A;  4OR0 A;  3B9L A;  2BXE A;  5IIH A;  2BXM A;  1E7E A;  5IFO A;  4F5T A;  3LU7 A;  1UOR A;  3JRY A;  1MA9 A;  2VDB A;  1E7H A;  4N0F D;  2BXA A;  2XVV A;  4K71 A;  2BX8 A;  2BXN A;  4IW1 A;  5ID7 A;  2BXB A;  1HK1 A;  4LUF A;  4G04 A;  3B9M A;  1BJ5 A;  5ID9 A; 
#chains in the Genus database with same CATH topology
 4ZCG A;  2BXG A;  5BPK A;  3LU8 A;  3PLA A;  2BXP A;  2BXD A;  3G9K D;  4FIP B;  4L8U A;  1FOU A;  4TQ1 A;  2V36 A;  1GNJ A;  2XW1 A;  2XVU A;  4K2C A;  3A73 A;  3NMU A;  1HK3 A;  2VUF A;  1H5W A;  3JQZ A;  4I9O A;  2LQH A;  2BXC A;  2I2Z A;  2XVQ A;  3H37 A;  2BXH A;  4L9Q A;  5IIU A;  2K0N A;  1E7B A;  4OTT A;  4MBE C;  3MHH B;  2DYO A;  4FJC B;  1J78 A;  1J7E A;  2JUH A;  2VUE A;  1LNS A;  5FUO A;  1E7G A;  4Z9O A;  1BKE A;  3NVI A;  4ZBR A;  1H9Z A;  1LOT A;  2XSI A;  1BM0 A;  2Z8J A;  4LB9 A;  5D7G A;  2QMC A;  3WHS A;  4FK5 B;  1O9X A;  1TXU A;  4N3Z A;  2KWF A;  4IW2 A;  5DQF A;  2Z8I A;  4LA0 A;  4LB2 A;  4GDX A;  5GIP A;  2OT3 A;  4F5V A;  2YDF A;  1GNI A;  2BXO A;  2I30 A;  2LQI A;  2DBW A;  1N5U A;  3B9M A;  3M99 C;  5GIO A;  4DM0 A;  1MUS A;  4Z69 A;  4ZBQ A;  5IIX A;  1MIW A;  1VZS A;  2BXI A;  5GIN A;  2DBX A;  3FNM A;  3BPJ A;  4LUH A;  4W4U B;  2GUT A;  2DBU A;  5DBY A;  2LXT A;  1E7A A;  2NNW A;  5GHK A;  4DHX B;  3A75 A;  2BXK A;  2E0X A;  3GA9 L;  5IJE A;  1MM8 A;  4S1Y A;  4HGK A;  3V08 A;  4F5U A;  3UIV A;  3V03 A;  1TF0 A;  2BXQ A;  2XW0 A;  3NVK A;  4G04 A;  2CKX A;  1HK4 A;  4OT2 A;  4PO0 A;  1HA2 A;  3GQU A;  3W1S A;  3SQJ A;  4F5S A;  1MIY A;  4EMX A;  2BXF A;  3V09 A;  4ZC6 A;  4ZUX V;  2BXL A;  1E7C A;  1VFI A;  1E7I A;  2EFH A;  2LOQ A;  5IJF A;  1MIV A;  2EFC A;  4L9K A;  4C31 B;  1E7F A;  1HK2 A;  2EFD A;  3ECP A;  2ROH A;  5IJ5 A;  4N0U D;  1HK5 A;  2XMO A;  2DG5 A;  3CX9 A;  4JK4 A;  2EFE A;  4J2V A;  1AO6 A;  3MHS B;  3ICX A;  1KW2 A;  4BKE A;  4HGM B;  4G01 A;  4WA6 B;  3TDL A;  1KXP D;  4ZBK A;  5HOZ A;  4E99 A;  3FWC C;  1IJG A;  3LU6 A;  3KIK A;  1E78 A;  2XVW A;  3H3A A;  3NVM A;  4G03 A;  4OR0 A;  3B9L A;  2OZB B;  2BXE A;  5IIH A;  4NAW B;  3GQX A;  1JNB A;  2BXM A;  1E7E A;  3WHR A;  5IFO A;  4F5T A;  3LU7 A;  2DYM A;  1UOR A;  3JRY A;  1MA9 A;  3SIU B;  2VDB A;  3KJL A;  1SB0 A;  4GDK B;  2QM6 A;  1E7H A;  4GDL B;  1MUH A;  4D7X A;  3FWB C;  4N0F D;  2BXA A;  2XVV A;  4K71 A;  3VQI A;  2QHB A;  4BY9 C;  2E0Y A;  2BX8 A;  2AJE A;  2AGH B;  2BXN A;  5B5T A;  1NT2 B;  4GG2 A;  4IW1 A;  5ID7 A;  3SIV B;  2BXB A;  4OTU A;  4M70 B;  3WHQ A;  2Z8K A;  2KBZ A;  4TQ0 A;  1HK1 A;  1KDX A;  4LUF A;  2LXS A;  2NQO A;  1BJ5 A;  5ID9 A; 
#chains in the Genus database with same CATH homology
 4ZCG A;  2BXG A;  5BPK A;  3LU8 A;  3PLA A;  2BXP A;  2BXD A;  3G9K D;  4FIP B;  4L8U A;  1FOU A;  4TQ1 A;  2V36 A;  1GNJ A;  2XW1 A;  2XVU A;  4K2C A;  3A73 A;  3NMU A;  1HK3 A;  1H5W A;  3JQZ A;  2XVQ A;  2BXC A;  2I2Z A;  3H37 A;  4L9Q A;  2BXH A;  5IIU A;  1E7B A;  4OTT A;  4MBE C;  3MHH B;  2DYO A;  4FJC B;  1J78 A;  1J7E A;  2JUH A;  2VUE A;  1LNS A;  5FUO A;  1E7G A;  4Z9O A;  1BKE A;  3NVI A;  4ZBR A;  1H9Z A;  1LOT A;  2XSI A;  1BM0 A;  2Z8J A;  4LB9 A;  5D7G A;  2QMC A;  3WHS A;  4FK5 B;  1O9X A;  1TXU A;  4N3Z A;  5DQF A;  4IW2 A;  2Z8I A;  4LA0 A;  4LB2 A;  4GDX A;  5GIP A;  2OT3 A;  4F5V A;  2YDF A;  1GNI A;  2BXO A;  2I30 A;  2DBW A;  1N5U A;  3B9M A;  3M99 C;  5GIO A;  4Z69 A;  4ZBQ A;  5IIX A;  1MIW A;  1VZS A;  2BXI A;  5GIN A;  2DBX A;  3FNM A;  4LUH A;  4W4U B;  2DBU A;  5DBY A;  1E7A A;  2NNW A;  5GHK A;  4DHX B;  3A75 A;  2BXK A;  2E0X A;  3GA9 L;  5IJE A;  4S1Y A;  4HGK A;  3V08 A;  4F5U A;  3UIV A;  3V03 A;  1TF0 A;  2BXQ A;  2XW0 A;  3NVK A;  4G04 A;  2CKX A;  1HK4 A;  4OT2 A;  4PO0 A;  1HA2 A;  3GQU A;  3W1S A;  3SQJ A;  4F5S A;  1MIY A;  4EMX A;  2BXF A;  3V09 A;  4ZC6 A;  4ZUX V;  2BXL A;  1E7C A;  1VFI A;  1E7I A;  2EFH A;  2LOQ A;  5IJF A;  1MIV A;  2EFC A;  4L9K A;  4C31 B;  1E7F A;  1HK2 A;  2EFD A;  2ROH A;  5IJ5 A;  4N0U D;  1HK5 A;  2XMO A;  2DG5 A;  3CX9 A;  4JK4 A;  2EFE A;  4J2V A;  1AO6 A;  3MHS B;  3ICX A;  1KW2 A;  4BKE A;  4HGM B;  4G01 A;  4WA6 B;  3TDL A;  1KXP D;  4ZBK A;  5HOZ A;  4E99 A;  3FWC C;  1IJG A;  3LU6 A;  3KIK A;  1E78 A;  2XVW A;  3H3A A;  3NVM A;  4G03 A;  4OR0 A;  3B9L A;  2OZB B;  2BXE A;  5IIH A;  4NAW B;  3GQX A;  1JNB A;  2BXM A;  1E7E A;  3WHR A;  5IFO A;  4F5T A;  3LU7 A;  2DYM A;  1UOR A;  3JRY A;  1MA9 A;  3SIU B;  2VDB A;  3KJL A;  4GDK B;  2QM6 A;  1E7H A;  4GDL B;  3FWB C;  4N0F D;  2BXA A;  2XVV A;  4K71 A;  3VQI A;  2QHB A;  4BY9 C;  2E0Y A;  2BX8 A;  2AJE A;  2BXN A;  5B5T A;  1NT2 B;  4GG2 A;  4IW1 A;  5ID7 A;  3SIV B;  2BXB A;  4OTU A;  4M70 B;  3WHQ A;  2Z8K A;  2KBZ A;  4TQ0 A;  1HK1 A;  4LUF A;  2VUF A;  2NQO A;  1BJ5 A;  5ID9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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