2BXMA

Human serum albumin complexed with myristate and indomethacin
Total Genus 225
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
225
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 225
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxmA05
2BXCA 3V08A 3JRYA 1N5UA 4L9QA 4F5TA 4ZBQA 4OR0A 4PO0A 5IIUA 4ZBRA 1E7GA 4K71A 4G04A 4LUFA 2XVUA 5IFOA 5FUOA 4L9KA 1E7EA 1KW2A 5DBYA 1BJ5A 3LU6A 4IW2A 5ID9A 4Z69A 5IIHA 2VDBA 2XW0A 3A73A 4IW1A 2BXEA 2BXBA 1BKEA 2BXAA 2BXIA 1AO6A 2BXNA 4JK4A 4EMXA 1TF0A 3V03A 1MA9A 4LUHA 5IJFA 1LOTA 1GNJA 4F5VA 2XVQA 4J2VA 3CX9A 4LB9A 1E7CA 2BXQA 2BX8A 1BM0A 1E7FA 2BXOA 2VUFA 1J78A 1HK4A 3TDLA 4L8UA 3LU7A 2BXHA 4F5SA 2XVVA 3LU8A 2I30A 2BXKA 5IJEA 4OT2A 4LB2A 5IJ5A 1H9ZA 4N0UD 4K2CA 4E99A 4S1YA 1J7EA 2BXGA 1E7IA 3JQZA 3UIVA 1GNIA 3B9LA 5HOZA 4HGMB 3B9MA 2BXDA 2XSIA 2YDFA 5IIXA 2BXMA 1KXPD 1O9XA 1HK2A 1E7BA 4F5UA 3SQJA 2BXPA 3V09A 5DQFA 2XVWA 4LA0A 4BKEA 1HK1A 2VUEA 5GHKA 5ID7A 1HK3A 4HGKA 4G03A 1E7AA 2XW1A 2BXFA 1E78A 1UORA 1E7HA 2I2ZA 1HA2A 4N0FD 2BXLA 1HK5A
chains in the Genus database with same CATH superfamily
2BXCA 2EFDA 3V08A 4D7XA 2JUHA 3JRYA 4BY9C 1N5UA 2LXSA 4DHXB 4L9QA 4F5TA 3M99C 1TXUA 3WHQA 4Z9OA 4ZBQA 1SB0A 4OR0A 4PO0A 2LXTA 4ZBRA 3WHRA 5IIUA 1E7GA 4K71A 4WA6B 4G04A 4LUFA 2V36A 2XVUA 2QMCA 4FK5B 4W4UB 2AGHB 4N3ZA 5IFOA 5FUOA 4L9KA 1E7EA 1KW2A 5DBYA 1BJ5A 3LU6A 4IW2A 5ID9A 3NVIA 4Z69A 2DBUA 5IIHA 2VDBA 3NVMA 2CKXA 2KBZA 4TQ1A 2XW0A 3A73A 4IW1A 2BXEA 4ZBKA 3G9KD 2BXBA 1BKEA 3VQIA 2BXAA 3W1SA 2E0XA 4GG2A 2BXIA 2EFHA 1AO6A 3FNMA 2BXNA 2LQHA 4JK4A 3GQXA 4EMXA 1VFIA 2QM6A 2DYOA 1TF0A 2DYMA 2KWFA 3MHSB 3GA9L 1JNBA 2ROHA 1MA9A 4LUHA 3V03A 1LOTA 1GNJA 2Z8IA 5IJFA 1KDXA 4F5VA 2XVQA 2NNWA 1VZSA 4GDKB 4J2VA 2XMOA 3BPJA 5B5TA 2QHBA 1MM8A 1MUSA 4NAWB 3CX9A 4LB9A 3NMUA 4GDXA 1E7CA 2BXQA 2BX8A 3ICXA 5GIOA 3SIUB 3SIVB 1BM0A 1E7FA 2BXOA 2Z8JA 4I9OA 1J78A 2VUFA 1HK4A 1LNSA 3TDLA 4L8UA 1MIVA 4OTUA 3LU7A 2BXHA 3GQUA 3KIKA 4ZUXV 4F5SA 5GINA 2XVVA 3LU8A 5BPKA 2I30A 2BXKA 4ZC6A 5IJEA 2AJEA 4OT2A 4LB2A 2E0YA 5GIPA 3H37A 2EFCA 4GDLB 4M70B 4MBEC 1H9ZA 4N0UD 5IJ5A 2DG5A 4K2CA 4E99A 4S1YA 1J7EA 3NVKA 2BXGA 1E7IA 1IJGA 2OT3A 3JQZA 1GNIA 3B9LA 5HOZA 3UIVA 4HGMB 3B9MA 2BXDA 2XSIA 2YDFA 5IIXA 3ECPA 3KJLA 2NQOA 2BXMA 1FOUA 4DM0A 1KXPD 1O9XA 4G01A 4FIPB 1HK2A 1E7BA 4F5UA 3SQJA 3PLAA 2BXPA 3V09A 5DQFA 4TQ0A 3WHSA 2XVWA 4LA0A 4BKEA 1HK1A 1MIWA 2DBWA 2VUEA 4ZCGA 5GHKA 2EFEA 3H3AA 1HK3A 5ID7A 2LQIA 2K0NA 4HGKA 1NT2B 4OTTA 3A75A 5D7GA 3FWCC 4G03A 2OZBB 1E7AA 2XW1A 2Z8KA 1MUHA 2BXFA 1E78A 1H5WA 1MIYA 3MHHB 1UORA 1E7HA 2DBXA 2I2ZA 3FWBC 1HA2A 4C31B 4N0FD 2LOQA 4FJCB 2BXLA 1HK5A 2GUTA
chains in the Genus database with same CATH topology
2BXCA 2EFDA 3V08A 2JUHA 3JRYA 4BY9C 1N5UA 4DHXB 4L9QA 4F5TA 3M99C 1TXUA 3WHQA 4Z9OA 4ZBQA 4OR0A 4PO0A 5IIUA 4ZBRA 3WHRA 1E7GA 4K71A 4WA6B 4G04A 4LUFA 2V36A 2XVUA 2QMCA 4FK5B 4W4UB 4N3ZA 5IFOA 5FUOA 4L9KA 1E7EA 1KW2A 5DBYA 1BJ5A 3LU6A 4IW2A 5ID9A 3NVIA 4Z69A 2DBUA 5IIHA 2VDBA 3NVMA 2CKXA 2KBZA 4TQ1A 2XW0A 3A73A 4IW1A 2BXEA 4ZBKA 3G9KD 2BXBA 1BKEA 3VQIA 2BXAA 3W1SA 2E0XA 4GG2A 2BXIA 2EFHA 1AO6A 3FNMA 2BXNA 4JK4A 3GQXA 4EMXA 1VFIA 2QM6A 2DYOA 1TF0A 2DYMA 3MHSB 3GA9L 1JNBA 2ROHA 1MA9A 4LUHA 3V03A 1LOTA 1GNJA 2Z8IA 5IJFA 4F5VA 2XVQA 2NNWA 1VZSA 4GDKB 4J2VA 2XMOA 5B5TA 2QHBA 4NAWB 3CX9A 4LB9A 3NMUA 4GDXA 1E7CA 2BXQA 2BX8A 3ICXA 5GIOA 3SIUB 3SIVB 1BM0A 1E7FA 2BXOA 2Z8JA 1J78A 2VUFA 1HK4A 1LNSA 3TDLA 4L8UA 1MIVA 4OTUA 3LU7A 2BXHA 3GQUA 3KIKA 4ZUXV 4F5SA 5GINA 2XVVA 3LU8A 5BPKA 2I30A 2BXKA 4ZC6A 5IJEA 2AJEA 4OT2A 4LB2A 2E0YA 5GIPA 3H37A 2EFCA 4GDLB 4M70B 4MBEC 1H9ZA 4N0UD 5IJ5A 2DG5A 4K2CA 4E99A 4S1YA 1J7EA 3NVKA 2BXGA 1E7IA 1IJGA 2OT3A 3JQZA 1GNIA 3B9LA 5HOZA 3UIVA 4HGMB 3B9MA 2BXDA 2XSIA 2YDFA 5IIXA 3KJLA 2NQOA 2BXMA 1FOUA 1KXPD 1O9XA 4G01A 4FIPB 1HK2A 1E7BA 4F5UA 3SQJA 3PLAA 2BXPA 3V09A 5DQFA 4TQ0A 3WHSA 2XVWA 4LA0A 4BKEA 1HK1A 1MIWA 2DBWA 2VUEA 4ZCGA 5GHKA 2EFEA 3H3AA 1HK3A 5ID7A 4HGKA 1NT2B 4OTTA 3A75A 5D7GA 3FWCC 4G03A 2OZBB 1E7AA 2XW1A 2Z8KA 2BXFA 1E78A 1H5WA 1MIYA 3MHHB 1UORA 1E7HA 2DBXA 2I2ZA 3FWBC 1HA2A 4C31B 4N0FD 2LOQA 4FJCB 2BXLA 1HK5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXC A;  3V08 A;  3JRY A;  1N5U A;  4L9Q A;  4F5T A;  4ZBQ A;  4OR0 A;  4PO0 A;  5IIU A;  4ZBR A;  1E7G A;  4K71 A;  4G04 A;  4LUF A;  2XVU A;  5IFO A;  5FUO A;  4L9K A;  1E7E A;  1KW2 A;  5DBY A;  1BJ5 A;  3LU6 A;  4IW2 A;  5ID9 A;  4Z69 A;  5IIH A;  2VDB A;  2XW0 A;  3A73 A;  4IW1 A;  2BXE A;  2BXB A;  1BKE A;  2BXA A;  2BXI A;  1AO6 A;  2BXN A;  4JK4 A;  4EMX A;  1TF0 A;  3V03 A;  1MA9 A;  4LUH A;  5IJF A;  1LOT A;  1GNJ A;  4F5V A;  2XVQ A;  4J2V A;  3CX9 A;  4LB9 A;  1E7C A;  2BXQ A;  2BX8 A;  1BM0 A;  1E7F A;  2BXO A;  2VUF A;  1J78 A;  1HK4 A;  3TDL A;  4L8U A;  3LU7 A;  2BXH A;  4F5S A;  2XVV A;  3LU8 A;  2I30 A;  2BXK A;  5IJE A;  4OT2 A;  4LB2 A;  5IJ5 A;  1H9Z A;  4N0U D;  4K2C A;  4E99 A;  4S1Y A;  1J7E A;  2BXG A;  1E7I A;  3JQZ A;  3UIV A;  1GNI A;  3B9L A;  5HOZ A;  4HGM B;  3B9M A;  2BXD A;  2XSI A;  2YDF A;  5IIX A;  2BXM A;  1KXP D;  1O9X A;  1HK2 A;  1E7B A;  4F5U A;  3SQJ A;  2BXP A;  3V09 A;  5DQF A;  2XVW A;  4LA0 A;  4BKE A;  1HK1 A;  2VUE A;  5GHK A;  5ID7 A;  1HK3 A;  4HGK A;  4G03 A;  1E7A A;  2XW1 A;  2BXF A;  1E78 A;  1UOR A;  1E7H A;  2I2Z A;  1HA2 A;  4N0F D;  2BXL A;  1HK5 A; 
#chains in the Genus database with same CATH topology
 2BXC A;  2EFD A;  3V08 A;  4D7X A;  2JUH A;  3JRY A;  4BY9 C;  1N5U A;  2LXS A;  4DHX B;  4L9Q A;  4F5T A;  3M99 C;  1TXU A;  3WHQ A;  4Z9O A;  4ZBQ A;  1SB0 A;  4OR0 A;  4PO0 A;  2LXT A;  4ZBR A;  3WHR A;  5IIU A;  1E7G A;  4K71 A;  4WA6 B;  4G04 A;  4LUF A;  2V36 A;  2XVU A;  2QMC A;  4FK5 B;  4W4U B;  2AGH B;  4N3Z A;  5IFO A;  5FUO A;  4L9K A;  1E7E A;  1KW2 A;  5DBY A;  1BJ5 A;  3LU6 A;  4IW2 A;  5ID9 A;  3NVI A;  4Z69 A;  2DBU A;  5IIH A;  2VDB A;  3NVM A;  2CKX A;  2KBZ A;  4TQ1 A;  2XW0 A;  3A73 A;  4IW1 A;  2BXE A;  4ZBK A;  3G9K D;  2BXB A;  1BKE A;  3VQI A;  2BXA A;  3W1S A;  2E0X A;  4GG2 A;  2BXI A;  2EFH A;  1AO6 A;  3FNM A;  2BXN A;  2LQH A;  4JK4 A;  3GQX A;  4EMX A;  1VFI A;  2QM6 A;  2DYO A;  1TF0 A;  2DYM A;  2KWF A;  3MHS B;  3GA9 L;  1JNB A;  2ROH A;  1MA9 A;  4LUH A;  3V03 A;  1LOT A;  1GNJ A;  2Z8I A;  5IJF A;  1KDX A;  4F5V A;  2XVQ A;  2NNW A;  1VZS A;  4GDK B;  4J2V A;  2XMO A;  3BPJ A;  5B5T A;  2QHB A;  1MM8 A;  1MUS A;  4NAW B;  3CX9 A;  4LB9 A;  3NMU A;  4GDX A;  1E7C A;  2BXQ A;  2BX8 A;  3ICX A;  5GIO A;  3SIU B;  3SIV B;  1BM0 A;  1E7F A;  2BXO A;  2Z8J A;  4I9O A;  1J78 A;  2VUF A;  1HK4 A;  1LNS A;  3TDL A;  4L8U A;  1MIV A;  4OTU A;  3LU7 A;  2BXH A;  3GQU A;  3KIK A;  4ZUX V;  4F5S A;  5GIN A;  2XVV A;  3LU8 A;  5BPK A;  2I30 A;  2BXK A;  4ZC6 A;  5IJE A;  2AJE A;  4OT2 A;  4LB2 A;  2E0Y A;  5GIP A;  3H37 A;  2EFC A;  4GDL B;  4M70 B;  4MBE C;  1H9Z A;  4N0U D;  5IJ5 A;  2DG5 A;  4K2C A;  4E99 A;  4S1Y A;  1J7E A;  3NVK A;  2BXG A;  1E7I A;  1IJG A;  2OT3 A;  3JQZ A;  1GNI A;  3B9L A;  5HOZ A;  3UIV A;  4HGM B;  3B9M A;  2BXD A;  2XSI A;  2YDF A;  5IIX A;  3ECP A;  3KJL A;  2NQO A;  2BXM A;  1FOU A;  4DM0 A;  1KXP D;  1O9X A;  4G01 A;  4FIP B;  1HK2 A;  1E7B A;  4F5U A;  3SQJ A;  3PLA A;  2BXP A;  3V09 A;  5DQF A;  4TQ0 A;  3WHS A;  2XVW A;  4LA0 A;  4BKE A;  1HK1 A;  1MIW A;  2DBW A;  2VUE A;  4ZCG A;  5GHK A;  2EFE A;  3H3A A;  1HK3 A;  5ID7 A;  2LQI A;  2K0N A;  4HGK A;  1NT2 B;  4OTT A;  3A75 A;  5D7G A;  3FWC C;  4G03 A;  2OZB B;  1E7A A;  2XW1 A;  2Z8K A;  1MUH A;  2BXF A;  1E78 A;  1H5W A;  1MIY A;  3MHH B;  1UOR A;  1E7H A;  2DBX A;  2I2Z A;  3FWB C;  1HA2 A;  4C31 B;  4N0F D;  2LOQ A;  4FJC B;  2BXL A;  1HK5 A;  2GUT A; 
#chains in the Genus database with same CATH homology
 2BXC A;  2EFD A;  3V08 A;  2JUH A;  3JRY A;  4BY9 C;  1N5U A;  4DHX B;  4L9Q A;  4F5T A;  3M99 C;  1TXU A;  3WHQ A;  4Z9O A;  4ZBQ A;  4OR0 A;  4PO0 A;  5IIU A;  4ZBR A;  3WHR A;  1E7G A;  4K71 A;  4WA6 B;  4G04 A;  4LUF A;  2V36 A;  2XVU A;  2QMC A;  4FK5 B;  4W4U B;  4N3Z A;  5IFO A;  5FUO A;  4L9K A;  1E7E A;  1KW2 A;  5DBY A;  1BJ5 A;  3LU6 A;  4IW2 A;  5ID9 A;  3NVI A;  4Z69 A;  2DBU A;  5IIH A;  2VDB A;  3NVM A;  2CKX A;  2KBZ A;  4TQ1 A;  2XW0 A;  3A73 A;  4IW1 A;  2BXE A;  4ZBK A;  3G9K D;  2BXB A;  1BKE A;  3VQI A;  2BXA A;  3W1S A;  2E0X A;  4GG2 A;  2BXI A;  2EFH A;  1AO6 A;  3FNM A;  2BXN A;  4JK4 A;  3GQX A;  4EMX A;  1VFI A;  2QM6 A;  2DYO A;  1TF0 A;  2DYM A;  3MHS B;  3GA9 L;  1JNB A;  2ROH A;  1MA9 A;  4LUH A;  3V03 A;  1LOT A;  1GNJ A;  2Z8I A;  5IJF A;  4F5V A;  2XVQ A;  2NNW A;  1VZS A;  4GDK B;  4J2V A;  2XMO A;  5B5T A;  2QHB A;  4NAW B;  3CX9 A;  4LB9 A;  3NMU A;  4GDX A;  1E7C A;  2BXQ A;  2BX8 A;  3ICX A;  5GIO A;  3SIU B;  3SIV B;  1BM0 A;  1E7F A;  2BXO A;  2Z8J A;  1J78 A;  2VUF A;  1HK4 A;  1LNS A;  3TDL A;  4L8U A;  1MIV A;  4OTU A;  3LU7 A;  2BXH A;  3GQU A;  3KIK A;  4ZUX V;  4F5S A;  5GIN A;  2XVV A;  3LU8 A;  5BPK A;  2I30 A;  2BXK A;  4ZC6 A;  5IJE A;  2AJE A;  4OT2 A;  4LB2 A;  2E0Y A;  5GIP A;  3H37 A;  2EFC A;  4GDL B;  4M70 B;  4MBE C;  1H9Z A;  4N0U D;  5IJ5 A;  2DG5 A;  4K2C A;  4E99 A;  4S1Y A;  1J7E A;  3NVK A;  2BXG A;  1E7I A;  1IJG A;  2OT3 A;  3JQZ A;  1GNI A;  3B9L A;  5HOZ A;  3UIV A;  4HGM B;  3B9M A;  2BXD A;  2XSI A;  2YDF A;  5IIX A;  3KJL A;  2NQO A;  2BXM A;  1FOU A;  1KXP D;  1O9X A;  4G01 A;  4FIP B;  1HK2 A;  1E7B A;  4F5U A;  3SQJ A;  3PLA A;  2BXP A;  3V09 A;  5DQF A;  4TQ0 A;  3WHS A;  2XVW A;  4LA0 A;  4BKE A;  1HK1 A;  1MIW A;  2DBW A;  2VUE A;  4ZCG A;  5GHK A;  2EFE A;  3H3A A;  1HK3 A;  5ID7 A;  4HGK A;  1NT2 B;  4OTT A;  3A75 A;  5D7G A;  3FWC C;  4G03 A;  2OZB B;  1E7A A;  2XW1 A;  2Z8K A;  2BXF A;  1E78 A;  1H5W A;  1MIY A;  3MHH B;  1UOR A;  1E7H A;  2DBX A;  2I2Z A;  3FWB C;  1HA2 A;  4C31 B;  4N0F D;  2LOQ A;  4FJC B;  2BXL A;  1HK5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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