2BXPA

Human serum albumin complexed with myristate and phenylbutazone
Total Genus 223
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
223
sequence length
581
structure length
581
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 223
structure length 581
sequence length 581
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxpA05
1HK2A 1HA2A 2BXKA 3SQJA 2BXMA 2XW0A 5IFOA 4L8UA 4F5TA 2BXHA 1BKEA 1E7IA 4LUHA 2BXOA 1KXPD 2XVQA 3TDLA 4N0FD 4K71A 3CX9A 3A73A 4G04A 1N5UA 3JQZA 2XW1A 5IIHA 2YDFA 1AO6A 4OR0A 3V08A 5FUOA 2BXLA 3B9MA 2I2ZA 5GHKA 4Z69A 1LOTA 4IW1A 2XVVA 4BKEA 4IW2A 1TF0A 1E78A 2BX8A 3V03A 3JRYA 4LB9A 1O9XA 4EMXA 1E7AA 2BXCA 4HGKA 5DQFA 2BXIA 5DBYA 1KW2A 4F5UA 2BXNA 1MA9A 3B9LA 3UIVA 2VUFA 5IJEA 1E7HA 1E7GA 5HOZA 3V09A 2BXGA 2VDBA 2BXAA 1H9ZA 1BJ5A 4OT2A 1UORA 1HK4A 2BXEA 1HK5A 1J7EA 5IJ5A 1E7EA 1HK1A 4L9KA 1GNJA 2BXBA 5ID7A 2BXFA 3LU8A 3LU7A 4LB2A 5IIXA 2BXDA 5ID9A 1BM0A 4S1YA 1J78A 4E99A 4K2CA 2XVWA 4LA0A 2I30A 3LU6A 1E7FA 4LUFA 2BXQA 4G03A 4JK4A 1HK3A 4ZBQA 4F5SA 4F5VA 2VUEA 1GNIA 1E7CA 4PO0A 1E7BA 4N0UD 5IIUA 2XSIA 2BXPA 4L9QA 4ZBRA 4J2VA 5IJFA 4HGMB 2XVUA
chains in the Genus database with same CATH superfamily
1HK2A 1HA2A 2BXKA 1KDXA 1MM8A 4ZBKA 1MIVA 2LQHA 3SQJA 3SIUB 3MHSB 2BXMA 2E0YA 2XW0A 1FOUA 5IFOA 4L8UA 4F5TA 2BXHA 1BKEA 1E7IA 4LUHA 2BXOA 3KJLA 2XVUA 1KXPD 4WA6B 4BY9C 2XVQA 3TDLA 4N0FD 4K71A 2EFEA 3CX9A 3NVKA 2EFCA 4TQ0A 3A73A 4G04A 1N5UA 3JQZA 2XW1A 5IIHA 2DYOA 3M99C 4GG2A 4D7XA 2YDFA 1AO6A 3MHHB 2LXSA 4MBEC 4ZUXV 3NVIA 4OR0A 2KBZA 3V08A 5FUOA 2BXLA 1H5WA 2ROHA 3ICXA 2Z8IA 3B9MA 2I2ZA 5GHKA 3GQXA 4Z69A 1NT2B 1LOTA 4IW1A 3BPJA 2EFHA 2XVVA 3WHSA 1JNBA 2NQOA 2EFDA 4BKEA 2XMOA 2OT3A 4G01A 2DG5A 4IW2A 4DM0A 1TF0A 4GDLB 1E78A 2BX8A 3V03A 3JRYA 4LB9A 1O9XA 3A75A 4EMXA 2V36A 3FWBC 1E7AA 2BXCA 4HGKA 5DQFA 4I9OA 5GIOA 2OZBB 4FK5B 3SIVB 2BXIA 5DBYA 1KW2A 4F5UA 2BXNA 1TXUA 1MA9A 3B9LA 4NAWB 3UIVA 2VUFA 3FNMA 5IJEA 3GQUA 4C31B 1E7HA 5GIPA 1E7GA 5HOZA 3V09A 2BXGA 2DBXA 2VDBA 2KWFA 3G9KD 2BXAA 1SB0A 3ECPA 1BJ5A 1H9ZA 4M70B 1IJGA 4OT2A 2Z8KA 1UORA 1HK4A 2LXTA 2Z8JA 2BXEA 2AJEA 4ZC6A 3WHRA 2LOQA 1HK5A 2QMCA 1J7EA 1MIWA 3H37A 1E7EA 1HK1A 2DYMA 4L9KA 5IJ5A 1MUHA 1GNJA 2BXBA 1MUSA 5D7GA 3NMUA 1VFIA 2DBUA 2JUHA 4GDKB 5ID7A 2BXFA 3LU8A 3LU7A 5B5TA 4LB2A 5IIXA 2BXDA 5ID9A 1BM0A 3WHQA 4TQ1A 2QM6A 4S1YA 1J78A 4E99A 2QHBA 4K2CA 4W4UB 3NVMA 2XVWA 4LA0A 2I30A 4N3ZA 3LU6A 2NNWA 1E7FA 2DBWA 4LUFA 2BXQA 1MIYA 3PLAA 4FIPB 4G03A 4JK4A 3GA9L 4FJCB 1HK3A 1VZSA 2K0NA 4OTUA 4ZBQA 3H3AA 4F5SA 5GINA 3KIKA 2E0XA 4F5VA 2AGHB 2VUEA 2GUTA 1GNIA 4DHXB 3FWCC 2LQIA 1E7CA 4PO0A 4ZCGA 3W1SA 4OTTA 5BPKA 1E7BA 4N0UD 5IIUA 2XSIA 2BXPA 4L9QA 4ZBRA 4J2VA 4Z9OA 4GDXA 3VQIA 5IJFA 4HGMB 1LNSA 2CKXA
chains in the Genus database with same CATH topology
1HK2A 1HA2A 2BXKA 4ZBKA 1MIVA 3SQJA 3SIUB 3MHSB 2BXMA 2E0YA 2XW0A 1FOUA 5IFOA 4L8UA 4F5TA 2BXHA 1BKEA 1E7IA 4LUHA 2BXOA 3KJLA 2XVUA 1KXPD 4WA6B 4BY9C 2XVQA 3TDLA 4N0FD 4K71A 2EFEA 3CX9A 3NVKA 2EFCA 4TQ0A 3A73A 4G04A 1N5UA 3JQZA 2XW1A 5IIHA 2DYOA 3M99C 4GG2A 2YDFA 1AO6A 3MHHB 4MBEC 4ZUXV 3NVIA 4OR0A 2KBZA 3V08A 5FUOA 2BXLA 1H5WA 2ROHA 3ICXA 2Z8IA 3B9MA 2I2ZA 5GHKA 3GQXA 4Z69A 1NT2B 1LOTA 4IW1A 3WHSA 2EFHA 2XVVA 5GIPA 1JNBA 2NQOA 2EFDA 4BKEA 2XMOA 2OT3A 4G01A 2DG5A 4IW2A 1TF0A 4GDLB 1E78A 2BX8A 3V03A 3JRYA 4LB9A 1O9XA 3A75A 4EMXA 2V36A 3FWBC 1E7AA 2BXCA 4HGKA 5DQFA 5GIOA 2OZBB 4FK5B 3SIVB 2BXIA 5DBYA 1KW2A 4F5UA 2BXNA 1TXUA 1MA9A 3B9LA 4NAWB 3UIVA 2VUFA 3FNMA 5IJEA 3GQUA 4C31B 1E7HA 1E7GA 5HOZA 3V09A 2BXGA 2DBXA 2VDBA 3G9KD 2BXAA 1BJ5A 1H9ZA 4M70B 1IJGA 4OT2A 2Z8KA 1UORA 1HK4A 2Z8JA 4ZC6A 2BXEA 2AJEA 3WHRA 2LOQA 1HK5A 2QMCA 1J7EA 1MIWA 3H37A 1E7EA 1HK1A 2DYMA 4L9KA 5IJ5A 1GNJA 2BXBA 5D7GA 3NMUA 1VFIA 2DBUA 2JUHA 4GDKB 5ID7A 2BXFA 3LU8A 3LU7A 5B5TA 4LB2A 5IIXA 2BXDA 5ID9A 1BM0A 3WHQA 4TQ1A 2QM6A 4S1YA 1J78A 4E99A 2QHBA 4K2CA 4W4UB 3NVMA 2XVWA 4LA0A 2I30A 4N3ZA 3LU6A 2NNWA 1E7FA 2DBWA 4LUFA 2BXQA 1MIYA 3PLAA 4FIPB 4G03A 4JK4A 3GA9L 4FJCB 1HK3A 1VZSA 4OTUA 4ZBQA 3H3AA 4F5SA 5GINA 3KIKA 2E0XA 4F5VA 2VUEA 1GNIA 4DHXB 3FWCC 1E7CA 4PO0A 4ZCGA 3W1SA 4OTTA 5BPKA 1E7BA 4N0UD 5IIUA 2XSIA 2BXPA 4L9QA 4ZBRA 4J2VA 4Z9OA 4GDXA 3VQIA 5IJFA 4HGMB 1LNSA 2CKXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HK2 A;  1HA2 A;  2BXK A;  3SQJ A;  2BXM A;  2XW0 A;  5IFO A;  4L8U A;  4F5T A;  2BXH A;  1BKE A;  1E7I A;  4LUH A;  2BXO A;  1KXP D;  2XVQ A;  3TDL A;  4N0F D;  4K71 A;  3CX9 A;  3A73 A;  4G04 A;  1N5U A;  3JQZ A;  2XW1 A;  5IIH A;  2YDF A;  1AO6 A;  4OR0 A;  3V08 A;  5FUO A;  2BXL A;  3B9M A;  2I2Z A;  5GHK A;  4Z69 A;  1LOT A;  4IW1 A;  2XVV A;  4BKE A;  4IW2 A;  1TF0 A;  1E78 A;  2BX8 A;  3V03 A;  3JRY A;  4LB9 A;  1O9X A;  4EMX A;  1E7A A;  2BXC A;  4HGK A;  5DQF A;  2BXI A;  5DBY A;  1KW2 A;  4F5U A;  2BXN A;  1MA9 A;  3B9L A;  3UIV A;  2VUF A;  5IJE A;  1E7H A;  1E7G A;  5HOZ A;  3V09 A;  2BXG A;  2VDB A;  2BXA A;  1H9Z A;  1BJ5 A;  4OT2 A;  1UOR A;  1HK4 A;  2BXE A;  1HK5 A;  1J7E A;  5IJ5 A;  1E7E A;  1HK1 A;  4L9K A;  1GNJ A;  2BXB A;  5ID7 A;  2BXF A;  3LU8 A;  3LU7 A;  4LB2 A;  5IIX A;  2BXD A;  5ID9 A;  1BM0 A;  4S1Y A;  1J78 A;  4E99 A;  4K2C A;  2XVW A;  4LA0 A;  2I30 A;  3LU6 A;  1E7F A;  4LUF A;  2BXQ A;  4G03 A;  4JK4 A;  1HK3 A;  4ZBQ A;  4F5S A;  4F5V A;  2VUE A;  1GNI A;  1E7C A;  4PO0 A;  1E7B A;  4N0U D;  5IIU A;  2XSI A;  2BXP A;  4L9Q A;  4ZBR A;  4J2V A;  5IJF A;  4HGM B;  2XVU A; 
#chains in the Genus database with same CATH topology
 1HK2 A;  1HA2 A;  2BXK A;  1KDX A;  1MM8 A;  4ZBK A;  1MIV A;  2LQH A;  3SQJ A;  3SIU B;  3MHS B;  2BXM A;  2E0Y A;  2XW0 A;  1FOU A;  5IFO A;  4L8U A;  4F5T A;  2BXH A;  1BKE A;  1E7I A;  4LUH A;  2BXO A;  3KJL A;  2XVU A;  1KXP D;  4WA6 B;  4BY9 C;  2XVQ A;  3TDL A;  4N0F D;  4K71 A;  2EFE A;  3CX9 A;  3NVK A;  2EFC A;  4TQ0 A;  3A73 A;  4G04 A;  1N5U A;  3JQZ A;  2XW1 A;  5IIH A;  2DYO A;  3M99 C;  4GG2 A;  4D7X A;  2YDF A;  1AO6 A;  3MHH B;  2LXS A;  4MBE C;  4ZUX V;  3NVI A;  4OR0 A;  2KBZ A;  3V08 A;  5FUO A;  2BXL A;  1H5W A;  2ROH A;  3ICX A;  2Z8I A;  3B9M A;  2I2Z A;  5GHK A;  3GQX A;  4Z69 A;  1NT2 B;  1LOT A;  4IW1 A;  3BPJ A;  2EFH A;  2XVV A;  3WHS A;  1JNB A;  2NQO A;  2EFD A;  4BKE A;  2XMO A;  2OT3 A;  4G01 A;  2DG5 A;  4IW2 A;  4DM0 A;  1TF0 A;  4GDL B;  1E78 A;  2BX8 A;  3V03 A;  3JRY A;  4LB9 A;  1O9X A;  3A75 A;  4EMX A;  2V36 A;  3FWB C;  1E7A A;  2BXC A;  4HGK A;  5DQF A;  4I9O A;  5GIO A;  2OZB B;  4FK5 B;  3SIV B;  2BXI A;  5DBY A;  1KW2 A;  4F5U A;  2BXN A;  1TXU A;  1MA9 A;  3B9L A;  4NAW B;  3UIV A;  2VUF A;  3FNM A;  5IJE A;  3GQU A;  4C31 B;  1E7H A;  5GIP A;  1E7G A;  5HOZ A;  3V09 A;  2BXG A;  2DBX A;  2VDB A;  2KWF A;  3G9K D;  2BXA A;  1SB0 A;  3ECP A;  1BJ5 A;  1H9Z A;  4M70 B;  1IJG A;  4OT2 A;  2Z8K A;  1UOR A;  1HK4 A;  2LXT A;  2Z8J A;  2BXE A;  2AJE A;  4ZC6 A;  3WHR A;  2LOQ A;  1HK5 A;  2QMC A;  1J7E A;  1MIW A;  3H37 A;  1E7E A;  1HK1 A;  2DYM A;  4L9K A;  5IJ5 A;  1MUH A;  1GNJ A;  2BXB A;  1MUS A;  5D7G A;  3NMU A;  1VFI A;  2DBU A;  2JUH A;  4GDK B;  5ID7 A;  2BXF A;  3LU8 A;  3LU7 A;  5B5T A;  4LB2 A;  5IIX A;  2BXD A;  5ID9 A;  1BM0 A;  3WHQ A;  4TQ1 A;  2QM6 A;  4S1Y A;  1J78 A;  4E99 A;  2QHB A;  4K2C A;  4W4U B;  3NVM A;  2XVW A;  4LA0 A;  2I30 A;  4N3Z A;  3LU6 A;  2NNW A;  1E7F A;  2DBW A;  4LUF A;  2BXQ A;  1MIY A;  3PLA A;  4FIP B;  4G03 A;  4JK4 A;  3GA9 L;  4FJC B;  1HK3 A;  1VZS A;  2K0N A;  4OTU A;  4ZBQ A;  3H3A A;  4F5S A;  5GIN A;  3KIK A;  2E0X A;  4F5V A;  2AGH B;  2VUE A;  2GUT A;  1GNI A;  4DHX B;  3FWC C;  2LQI A;  1E7C A;  4PO0 A;  4ZCG A;  3W1S A;  4OTT A;  5BPK A;  1E7B A;  4N0U D;  5IIU A;  2XSI A;  2BXP A;  4L9Q A;  4ZBR A;  4J2V A;  4Z9O A;  4GDX A;  3VQI A;  5IJF A;  4HGM B;  1LNS A;  2CKX A; 
#chains in the Genus database with same CATH homology
 1HK2 A;  1HA2 A;  2BXK A;  4ZBK A;  1MIV A;  3SQJ A;  3SIU B;  3MHS B;  2BXM A;  2E0Y A;  2XW0 A;  1FOU A;  5IFO A;  4L8U A;  4F5T A;  2BXH A;  1BKE A;  1E7I A;  4LUH A;  2BXO A;  3KJL A;  2XVU A;  1KXP D;  4WA6 B;  4BY9 C;  2XVQ A;  3TDL A;  4N0F D;  4K71 A;  2EFE A;  3CX9 A;  3NVK A;  2EFC A;  4TQ0 A;  3A73 A;  4G04 A;  1N5U A;  3JQZ A;  2XW1 A;  5IIH A;  2DYO A;  3M99 C;  4GG2 A;  2YDF A;  1AO6 A;  3MHH B;  4MBE C;  4ZUX V;  3NVI A;  4OR0 A;  2KBZ A;  3V08 A;  5FUO A;  2BXL A;  1H5W A;  2ROH A;  3ICX A;  2Z8I A;  3B9M A;  2I2Z A;  5GHK A;  3GQX A;  4Z69 A;  1NT2 B;  1LOT A;  4IW1 A;  3WHS A;  2EFH A;  2XVV A;  5GIP A;  1JNB A;  2NQO A;  2EFD A;  4BKE A;  2XMO A;  2OT3 A;  4G01 A;  2DG5 A;  4IW2 A;  1TF0 A;  4GDL B;  1E78 A;  2BX8 A;  3V03 A;  3JRY A;  4LB9 A;  1O9X A;  3A75 A;  4EMX A;  2V36 A;  3FWB C;  1E7A A;  2BXC A;  4HGK A;  5DQF A;  5GIO A;  2OZB B;  4FK5 B;  3SIV B;  2BXI A;  5DBY A;  1KW2 A;  4F5U A;  2BXN A;  1TXU A;  1MA9 A;  3B9L A;  4NAW B;  3UIV A;  2VUF A;  3FNM A;  5IJE A;  3GQU A;  4C31 B;  1E7H A;  1E7G A;  5HOZ A;  3V09 A;  2BXG A;  2DBX A;  2VDB A;  3G9K D;  2BXA A;  1BJ5 A;  1H9Z A;  4M70 B;  1IJG A;  4OT2 A;  2Z8K A;  1UOR A;  1HK4 A;  2Z8J A;  4ZC6 A;  2BXE A;  2AJE A;  3WHR A;  2LOQ A;  1HK5 A;  2QMC A;  1J7E A;  1MIW A;  3H37 A;  1E7E A;  1HK1 A;  2DYM A;  4L9K A;  5IJ5 A;  1GNJ A;  2BXB A;  5D7G A;  3NMU A;  1VFI A;  2DBU A;  2JUH A;  4GDK B;  5ID7 A;  2BXF A;  3LU8 A;  3LU7 A;  5B5T A;  4LB2 A;  5IIX A;  2BXD A;  5ID9 A;  1BM0 A;  3WHQ A;  4TQ1 A;  2QM6 A;  4S1Y A;  1J78 A;  4E99 A;  2QHB A;  4K2C A;  4W4U B;  3NVM A;  2XVW A;  4LA0 A;  2I30 A;  4N3Z A;  3LU6 A;  2NNW A;  1E7F A;  2DBW A;  4LUF A;  2BXQ A;  1MIY A;  3PLA A;  4FIP B;  4G03 A;  4JK4 A;  3GA9 L;  4FJC B;  1HK3 A;  1VZS A;  4OTU A;  4ZBQ A;  3H3A A;  4F5S A;  5GIN A;  3KIK A;  2E0X A;  4F5V A;  2VUE A;  1GNI A;  4DHX B;  3FWC C;  1E7C A;  4PO0 A;  4ZCG A;  3W1S A;  4OTT A;  5BPK A;  1E7B A;  4N0U D;  5IIU A;  2XSI A;  2BXP A;  4L9Q A;  4ZBR A;  4J2V A;  4Z9O A;  4GDX A;  3VQI A;  5IJF A;  4HGM B;  1LNS A;  2CKX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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