2BXQA

Human serum albumin complexed with myristate, phenylbutazone and indomethacin
Total Genus 224
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKEEQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 224
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxqA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxqA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxqA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxqA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxqA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxqA05
5IIXA 4J2VA 5DQFA 4F5VA 1HK1A 2VUEA 2XW1A 1GNIA 2XVUA 2BXHA 4G04A 1KW2A 3CX9A 5DBYA 2BX8A 1J78A 1O9XA 2BXLA 5IJFA 1HA2A 1TF0A 3V08A 4L9QA 2YDFA 1AO6A 1E7BA 3JQZA 2BXQA 5IJEA 5IIHA 2XSIA 1BM0A 1E78A 4LUFA 3B9MA 4K71A 1LOTA 2BXPA 4EMXA 1E7IA 1E7GA 5HOZA 5FUOA 2BXCA 1HK3A 1KXPD 4LA0A 4OR0A 3LU7A 4LB2A 4LB9A 4OT2A 4ZBRA 3LU6A 5ID7A 2BXDA 3TDLA 4N0UD 1N5UA 4HGKA 4G03A 4ZBQA 4BKEA 2BXAA 4F5UA 2BXIA 1HK4A 4JK4A 4Z69A 1J7EA 3A73A 4LUHA 4PO0A 2BXNA 1UORA 3SQJA 4L8UA 3JRYA 4S1YA 1H9ZA 4L9KA 2BXEA 2BXBA 4N0FD 2I2ZA 4IW1A 5IIUA 5GHKA 2I30A 5IFOA 1E7FA 2BXMA 2BXKA 5ID9A 1MA9A 2XW0A 4F5SA 4HGMB 1BJ5A 1E7AA 1E7EA 2XVWA 1HK5A 3LU8A 3V09A 2VDBA 4E99A 1BKEA 3UIVA 3B9LA 1HK2A 1E7HA 2XVQA 2XVVA 3V03A 5IJ5A 4IW2A 1GNJA 2VUFA 4F5TA 2BXFA 2BXGA 1E7CA 2BXOA 4K2CA
chains in the Genus database with same CATH superfamily
2KBZA 2AGHB 4J2VA 5IIXA 4FK5B 1SB0A 2Z8JA 5DQFA 4F5VA 1HK1A 1MUSA 3H37A 2CKXA 2LQHA 2VUEA 2XW1A 4W4UB 1GNIA 1TXUA 2XVUA 4ZCGA 3A75A 4D7XA 4WA6B 2BXHA 4G04A 1KW2A 2EFCA 3CX9A 3H3AA 5DBYA 2BX8A 1NT2B 2DBUA 1FOUA 2DYMA 1J78A 1O9XA 4G01A 4C31B 2OT3A 2BXLA 5IJFA 2V36A 1HA2A 1TF0A 3V08A 4GG2A 2YDFA 4L9QA 1AO6A 1MUHA 4Z9OA 4I9OA 1E7BA 3JQZA 4N3ZA 2BXQA 5IJEA 3FWCC 5IIHA 3GQUA 2XSIA 2DYOA 2QHBA 3BPJA 2LXTA 3FWBC 1BM0A 1E78A 4LUFA 3VQIA 3B9MA 4K71A 1LOTA 2EFDA 3GQXA 4FJCB 2BXPA 4EMXA 1MIWA 1E7IA 1VFIA 1E7GA 5HOZA 5D7GA 5FUOA 2BXCA 1HK3A 2DG5A 1KXPD 2LXSA 1JNBA 5GIPA 2NQOA 4LA0A 4OR0A 3NVIA 3LU7A 4LB2A 1VZSA 4LB9A 4OT2A 2LOQA 4ZBRA 3LU6A 2LQIA 5GINA 1KDXA 5ID7A 2BXDA 3TDLA 2JUHA 2XMOA 4N0UD 1N5UA 4HGKA 4G03A 4ZBQA 3KIKA 2BXAA 4BKEA 3MHSB 4GDLB 2E0YA 4F5UA 2BXIA 4TQ0A 5BPKA 1HK4A 4M70B 4JK4A 1H5WA 4Z69A 5B5TA 3NMUA 3SIVB 1J7EA 2Z8IA 3A73A 4MBEC 4TQ1A 2EFEA 4LUHA 4PO0A 2BXNA 3FNMA 1UORA 4ZBKA 3SQJA 2QMCA 4L8UA 2OZBB 3JRYA 3MHHB 4S1YA 1H9ZA 4L9KA 2GUTA 2BXEA 4OTUA 2BXBA 4N0FD 2I2ZA 4ZC6A 4DHXB 3ECPA 1MM8A 4IW1A 2E0XA 2Z8KA 5IIUA 5GHKA 2I30A 5IFOA 1E7FA 1MIVA 2K0NA 3NVKA 2KWFA 2BXMA 2ROHA 3PLAA 2BXKA 5ID9A 3G9KD 1MA9A 2XW0A 4OTTA 4F5SA 4HGMB 1LNSA 1BJ5A 1E7AA 1E7EA 2XVWA 1HK5A 4DM0A 3LU8A 3NVMA 2AJEA 2VDBA 3V09A 3WHSA 4E99A 1BKEA 2QM6A 3UIVA 3B9LA 3WHRA 2EFHA 1HK2A 2NNWA 3KJLA 3M99C 4FIPB 3SIUB 1E7HA 2XVQA 2XVVA 3V03A 4ZUXV 3GA9L 4IW2A 5IJ5A 1GNJA 2DBXA 4GDXA 2VUFA 4BY9C 4F5TA 1MIYA 1IJGA 2BXFA 1E7CA 2BXGA 2DBWA 3ICXA 3WHQA 3W1SA 4NAWB 2BXOA 4K2CA 4GDKB 5GIOA
chains in the Genus database with same CATH topology
2KBZA 5IIXA 4J2VA 4FK5B 2Z8JA 5DQFA 4F5VA 1HK1A 3H37A 2CKXA 2VUEA 2XW1A 4W4UB 1GNIA 1TXUA 2XVUA 4ZCGA 3A75A 4WA6B 2BXHA 4G04A 1KW2A 2EFCA 3CX9A 3H3AA 5DBYA 2BX8A 1NT2B 2DBUA 1FOUA 2DYMA 1J78A 1O9XA 4G01A 4C31B 2OT3A 2BXLA 5IJFA 2V36A 1HA2A 1TF0A 3V08A 4GG2A 2YDFA 4L9QA 1AO6A 4Z9OA 1E7BA 3JQZA 4N3ZA 2BXQA 5IJEA 3FWCC 5IIHA 3GQUA 2XSIA 2DYOA 2QHBA 3FWBC 1BM0A 1E78A 4LUFA 3VQIA 3B9MA 4K71A 1LOTA 2EFDA 3GQXA 4FJCB 2BXPA 4EMXA 1MIWA 1E7IA 1VFIA 1E7GA 5HOZA 5D7GA 5FUOA 2BXCA 1HK3A 2DG5A 1KXPD 1JNBA 5GIPA 2NQOA 4LA0A 4OR0A 3NVIA 3LU7A 4LB2A 1VZSA 4LB9A 4OT2A 2LOQA 4ZBRA 3LU6A 5GINA 5ID7A 2BXDA 3TDLA 2JUHA 2XMOA 4N0UD 1N5UA 4HGKA 4G03A 4ZBQA 3KIKA 2BXAA 4BKEA 3MHSB 4GDLB 2E0YA 4F5UA 2BXIA 4TQ0A 5BPKA 1HK4A 4M70B 4JK4A 1H5WA 4Z69A 5B5TA 3NMUA 3SIVB 1J7EA 2Z8IA 3A73A 4MBEC 4TQ1A 2EFEA 4LUHA 4PO0A 2BXNA 3FNMA 1UORA 4ZBKA 3SQJA 2QMCA 4L8UA 2OZBB 3JRYA 3MHHB 4S1YA 1H9ZA 4L9KA 4OTUA 2BXEA 4ZC6A 2BXBA 4N0FD 2I2ZA 4DHXB 4IW1A 2E0XA 2Z8KA 5IIUA 5GHKA 2I30A 5IFOA 1E7FA 1MIVA 3NVKA 2BXMA 2ROHA 3PLAA 2BXKA 5ID9A 3G9KD 1MA9A 2XW0A 4OTTA 4F5SA 4HGMB 1LNSA 1BJ5A 1E7AA 1E7EA 2XVWA 1HK5A 3LU8A 3NVMA 2AJEA 2VDBA 3V09A 3WHSA 4E99A 1BKEA 2QM6A 3UIVA 3B9LA 3WHRA 2EFHA 1HK2A 2NNWA 3KJLA 3M99C 4FIPB 3SIUB 1E7HA 2XVQA 2XVVA 3V03A 4ZUXV 3GA9L 4IW2A 5IJ5A 1GNJA 2DBXA 4GDXA 2VUFA 4BY9C 4F5TA 1MIYA 1IJGA 2BXFA 1E7CA 2BXGA 2DBWA 3ICXA 3WHQA 3W1SA 4NAWB 2BXOA 4K2CA 4GDKB 5GIOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IIX A;  4J2V A;  5DQF A;  4F5V A;  1HK1 A;  2VUE A;  2XW1 A;  1GNI A;  2XVU A;  2BXH A;  4G04 A;  1KW2 A;  3CX9 A;  5DBY A;  2BX8 A;  1J78 A;  1O9X A;  2BXL A;  5IJF A;  1HA2 A;  1TF0 A;  3V08 A;  4L9Q A;  2YDF A;  1AO6 A;  1E7B A;  3JQZ A;  2BXQ A;  5IJE A;  5IIH A;  2XSI A;  1BM0 A;  1E78 A;  4LUF A;  3B9M A;  4K71 A;  1LOT A;  2BXP A;  4EMX A;  1E7I A;  1E7G A;  5HOZ A;  5FUO A;  2BXC A;  1HK3 A;  1KXP D;  4LA0 A;  4OR0 A;  3LU7 A;  4LB2 A;  4LB9 A;  4OT2 A;  4ZBR A;  3LU6 A;  5ID7 A;  2BXD A;  3TDL A;  4N0U D;  1N5U A;  4HGK A;  4G03 A;  4ZBQ A;  4BKE A;  2BXA A;  4F5U A;  2BXI A;  1HK4 A;  4JK4 A;  4Z69 A;  1J7E A;  3A73 A;  4LUH A;  4PO0 A;  2BXN A;  1UOR A;  3SQJ A;  4L8U A;  3JRY A;  4S1Y A;  1H9Z A;  4L9K A;  2BXE A;  2BXB A;  4N0F D;  2I2Z A;  4IW1 A;  5IIU A;  5GHK A;  2I30 A;  5IFO A;  1E7F A;  2BXM A;  2BXK A;  5ID9 A;  1MA9 A;  2XW0 A;  4F5S A;  4HGM B;  1BJ5 A;  1E7A A;  1E7E A;  2XVW A;  1HK5 A;  3LU8 A;  3V09 A;  2VDB A;  4E99 A;  1BKE A;  3UIV A;  3B9L A;  1HK2 A;  1E7H A;  2XVQ A;  2XVV A;  3V03 A;  5IJ5 A;  4IW2 A;  1GNJ A;  2VUF A;  4F5T A;  2BXF A;  2BXG A;  1E7C A;  2BXO A;  4K2C A; 
#chains in the Genus database with same CATH topology
 2KBZ A;  2AGH B;  4J2V A;  5IIX A;  4FK5 B;  1SB0 A;  2Z8J A;  5DQF A;  4F5V A;  1HK1 A;  1MUS A;  3H37 A;  2CKX A;  2LQH A;  2VUE A;  2XW1 A;  4W4U B;  1GNI A;  1TXU A;  2XVU A;  4ZCG A;  3A75 A;  4D7X A;  4WA6 B;  2BXH A;  4G04 A;  1KW2 A;  2EFC A;  3CX9 A;  3H3A A;  5DBY A;  2BX8 A;  1NT2 B;  2DBU A;  1FOU A;  2DYM A;  1J78 A;  1O9X A;  4G01 A;  4C31 B;  2OT3 A;  2BXL A;  5IJF A;  2V36 A;  1HA2 A;  1TF0 A;  3V08 A;  4GG2 A;  2YDF A;  4L9Q A;  1AO6 A;  1MUH A;  4Z9O A;  4I9O A;  1E7B A;  3JQZ A;  4N3Z A;  2BXQ A;  5IJE A;  3FWC C;  5IIH A;  3GQU A;  2XSI A;  2DYO A;  2QHB A;  3BPJ A;  2LXT A;  3FWB C;  1BM0 A;  1E78 A;  4LUF A;  3VQI A;  3B9M A;  4K71 A;  1LOT A;  2EFD A;  3GQX A;  4FJC B;  2BXP A;  4EMX A;  1MIW A;  1E7I A;  1VFI A;  1E7G A;  5HOZ A;  5D7G A;  5FUO A;  2BXC A;  1HK3 A;  2DG5 A;  1KXP D;  2LXS A;  1JNB A;  5GIP A;  2NQO A;  4LA0 A;  4OR0 A;  3NVI A;  3LU7 A;  4LB2 A;  1VZS A;  4LB9 A;  4OT2 A;  2LOQ A;  4ZBR A;  3LU6 A;  2LQI A;  5GIN A;  1KDX A;  5ID7 A;  2BXD A;  3TDL A;  2JUH A;  2XMO A;  4N0U D;  1N5U A;  4HGK A;  4G03 A;  4ZBQ A;  3KIK A;  2BXA A;  4BKE A;  3MHS B;  4GDL B;  2E0Y A;  4F5U A;  2BXI A;  4TQ0 A;  5BPK A;  1HK4 A;  4M70 B;  4JK4 A;  1H5W A;  4Z69 A;  5B5T A;  3NMU A;  3SIV B;  1J7E A;  2Z8I A;  3A73 A;  4MBE C;  4TQ1 A;  2EFE A;  4LUH A;  4PO0 A;  2BXN A;  3FNM A;  1UOR A;  4ZBK A;  3SQJ A;  2QMC A;  4L8U A;  2OZB B;  3JRY A;  3MHH B;  4S1Y A;  1H9Z A;  4L9K A;  2GUT A;  2BXE A;  4OTU A;  2BXB A;  4N0F D;  2I2Z A;  4ZC6 A;  4DHX B;  3ECP A;  1MM8 A;  4IW1 A;  2E0X A;  2Z8K A;  5IIU A;  5GHK A;  2I30 A;  5IFO A;  1E7F A;  1MIV A;  2K0N A;  3NVK A;  2KWF A;  2BXM A;  2ROH A;  3PLA A;  2BXK A;  5ID9 A;  3G9K D;  1MA9 A;  2XW0 A;  4OTT A;  4F5S A;  4HGM B;  1LNS A;  1BJ5 A;  1E7A A;  1E7E A;  2XVW A;  1HK5 A;  4DM0 A;  3LU8 A;  3NVM A;  2AJE A;  2VDB A;  3V09 A;  3WHS A;  4E99 A;  1BKE A;  2QM6 A;  3UIV A;  3B9L A;  3WHR A;  2EFH A;  1HK2 A;  2NNW A;  3KJL A;  3M99 C;  4FIP B;  3SIU B;  1E7H A;  2XVQ A;  2XVV A;  3V03 A;  4ZUX V;  3GA9 L;  4IW2 A;  5IJ5 A;  1GNJ A;  2DBX A;  4GDX A;  2VUF A;  4BY9 C;  4F5T A;  1MIY A;  1IJG A;  2BXF A;  1E7C A;  2BXG A;  2DBW A;  3ICX A;  3WHQ A;  3W1S A;  4NAW B;  2BXO A;  4K2C A;  4GDK B;  5GIO A; 
#chains in the Genus database with same CATH homology
 2KBZ A;  5IIX A;  4J2V A;  4FK5 B;  2Z8J A;  5DQF A;  4F5V A;  1HK1 A;  3H37 A;  2CKX A;  2VUE A;  2XW1 A;  4W4U B;  1GNI A;  1TXU A;  2XVU A;  4ZCG A;  3A75 A;  4WA6 B;  2BXH A;  4G04 A;  1KW2 A;  2EFC A;  3CX9 A;  3H3A A;  5DBY A;  2BX8 A;  1NT2 B;  2DBU A;  1FOU A;  2DYM A;  1J78 A;  1O9X A;  4G01 A;  4C31 B;  2OT3 A;  2BXL A;  5IJF A;  2V36 A;  1HA2 A;  1TF0 A;  3V08 A;  4GG2 A;  2YDF A;  4L9Q A;  1AO6 A;  4Z9O A;  1E7B A;  3JQZ A;  4N3Z A;  2BXQ A;  5IJE A;  3FWC C;  5IIH A;  3GQU A;  2XSI A;  2DYO A;  2QHB A;  3FWB C;  1BM0 A;  1E78 A;  4LUF A;  3VQI A;  3B9M A;  4K71 A;  1LOT A;  2EFD A;  3GQX A;  4FJC B;  2BXP A;  4EMX A;  1MIW A;  1E7I A;  1VFI A;  1E7G A;  5HOZ A;  5D7G A;  5FUO A;  2BXC A;  1HK3 A;  2DG5 A;  1KXP D;  1JNB A;  5GIP A;  2NQO A;  4LA0 A;  4OR0 A;  3NVI A;  3LU7 A;  4LB2 A;  1VZS A;  4LB9 A;  4OT2 A;  2LOQ A;  4ZBR A;  3LU6 A;  5GIN A;  5ID7 A;  2BXD A;  3TDL A;  2JUH A;  2XMO A;  4N0U D;  1N5U A;  4HGK A;  4G03 A;  4ZBQ A;  3KIK A;  2BXA A;  4BKE A;  3MHS B;  4GDL B;  2E0Y A;  4F5U A;  2BXI A;  4TQ0 A;  5BPK A;  1HK4 A;  4M70 B;  4JK4 A;  1H5W A;  4Z69 A;  5B5T A;  3NMU A;  3SIV B;  1J7E A;  2Z8I A;  3A73 A;  4MBE C;  4TQ1 A;  2EFE A;  4LUH A;  4PO0 A;  2BXN A;  3FNM A;  1UOR A;  4ZBK A;  3SQJ A;  2QMC A;  4L8U A;  2OZB B;  3JRY A;  3MHH B;  4S1Y A;  1H9Z A;  4L9K A;  4OTU A;  2BXE A;  4ZC6 A;  2BXB A;  4N0F D;  2I2Z A;  4DHX B;  4IW1 A;  2E0X A;  2Z8K A;  5IIU A;  5GHK A;  2I30 A;  5IFO A;  1E7F A;  1MIV A;  3NVK A;  2BXM A;  2ROH A;  3PLA A;  2BXK A;  5ID9 A;  3G9K D;  1MA9 A;  2XW0 A;  4OTT A;  4F5S A;  4HGM B;  1LNS A;  1BJ5 A;  1E7A A;  1E7E A;  2XVW A;  1HK5 A;  3LU8 A;  3NVM A;  2AJE A;  2VDB A;  3V09 A;  3WHS A;  4E99 A;  1BKE A;  2QM6 A;  3UIV A;  3B9L A;  3WHR A;  2EFH A;  1HK2 A;  2NNW A;  3KJL A;  3M99 C;  4FIP B;  3SIU B;  1E7H A;  2XVQ A;  2XVV A;  3V03 A;  4ZUX V;  3GA9 L;  4IW2 A;  5IJ5 A;  1GNJ A;  2DBX A;  4GDX A;  2VUF A;  4BY9 C;  4F5T A;  1MIY A;  1IJG A;  2BXF A;  1E7C A;  2BXG A;  2DBW A;  3ICX A;  3WHQ A;  3W1S A;  4NAW B;  2BXO A;  4K2C A;  4GDK B;  5GIO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...