2DBUA

Crystal structure of gamma-glutamyltranspeptidase from escherichia coli
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
359
structure length
359
Chain Sequence
APPVSYGVEEDVFHPVRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of gamma-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli k12
molecule keywords Gamma-glutamyltranspeptidase
total genus 99
structure length 359
sequence length 359
chains with identical sequence C
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2005-12-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2dbuA02
2DBWA 2Z8JA 2DBXA 2Z8IA 2NQOA 3FNMA 4GG2A 2V36A 2E0XA 2QM6A 3A75A 4GDXA 2DBUA 4Z9OA 2E0YA 4OTTA 2Z8KA 4ZCGA 4OTUA 3WHQA 5BPKA 4ZBKA 3WHSA 2QMCA 3WHRA 5B5TA 4ZC6A 2DG5A
chains in the Genus database with same CATH superfamily
4GDLB 2AJEA 2DYOA 5ID9A 5IIHA 4Z69A 4FIPB 4N0UD 4K71A 3SQJA 2E0XA 2QM6A 5IIXA 2BXCA 2LQIA 2DYMA 1E7CA 2EFEA 3B9MA 4JK4A 3TDLA 3ECPA 3PLAA 1TXUA 2OT3A 4OTTA 1GNIA 4L8UA 3LU8A 4F5VA 1E7GA 4OTUA 1MIYA 2AGHB 2I2ZA 3ICXA 3JRYA 2OZBB 2ROHA 5GINA 1H5WA 4G01A 1MM8A 3WHRA 5B5TA 3GA9L 4S1YA 4ZC6A 2BXAA 5GIOA 3H37A 2EFHA 2KBZA 4LB9A 4HGKA 4DHXB 5GHKA 2BXOA 2Z8JA 5DBYA 2BXQA 2LXTA 4FK5B 1N5UA 3FNMA 4F5SA 3NVKA 1E7IA 3M99C 4J2VA 4LUHA 2EFCA 4N3ZA 1MIVA 5IJ5A 1TF0A 4W4UB 2XSIA 1E78A 1E7EA 2BXIA 2CKXA 3H3AA 4Z9OA 2XW1A 2E0YA 1FOUA 4LA0A 1HK5A 4ZBQA 4BKEA 4D7XA 4IW2A 3NMUA 3G9KD 3GQXA 3VQIA 2XVVA 3WHQA 1MUHA 5FUOA 2BXKA 3MHHB 3KJLA 3SIVB 5D7GA 2QMCA 2XVWA 4G03A 3LU6A 2K0NA 2XW0A 3GQUA 3W1SA 3V03A 4E99A 4EMXA 1MUSA 1BKEA 3B9LA 5HOZA 4TQ1A 3FWBC 4HGMB 4LUFA 2Z8IA 2LXSA 4M70B 2BXHA 4PO0A 3UIVA 1KDXA 4C31B 2XVUA 1E7FA 1J7EA 3A75A 4FJCB 2BXMA 3A73A 4GDXA 1MIWA 4I9OA 4OR0A 2VUFA 4L9QA 2XMOA 4MBEC 5IFOA 1AO6A 4LB2A 1GNJA 1NT2B 1BM0A 1HA2A 4WA6B 2LQHA 5BPKA 4GDKB 3CX9A 1LNSA 4ZBKA 1HK1A 1JNBA 5IJEA 3WHSA 5IJFA 4G04A 1H9ZA 1KXPD 2BXGA 2I30A 3JQZA 4IW1A 1HK4A 4L9KA 2GUTA 3LU7A 2QHBA 1E7AA 2XVQA 2BXFA 4N0FD 2DBWA 3V09A 2DBXA 2YDFA 2NQOA 1IJGA 4F5TA 4TQ0A 1HK3A 1UORA 4GG2A 1O9XA 2BXLA 2V36A 1SB0A 1HK2A 5IIUA 4BY9C 2EFDA 2NNWA 3NVIA 3V08A 1KW2A 3NVMA 1J78A 2DBUA 4OT2A 4DM0A 1MA9A 3SIUB 2Z8KA 4NAWB 2BXBA 4ZUXV 4ZCGA 1E7HA 2VDBA 2KWFA 3BPJA 1BJ5A 1VZSA 2BXDA 4F5UA 2LOQA 3KIKA 5ID7A 2BX8A 2BXPA 2JUHA 2VUEA 4K2CA 5DQFA 5GIPA 2BXNA 1VFIA 3FWCC 3MHSB 1LOTA 2BXEA 4ZBRA 2DG5A 1E7BA
chains in the Genus database with same CATH topology
4GDLB 2AJEA 2DYOA 5ID9A 5IIHA 4Z69A 4FIPB 4N0UD 4K71A 3SQJA 2E0XA 2QM6A 5IIXA 2BXCA 3TDLA 2DYMA 1E7CA 2EFEA 3B9MA 4JK4A 3PLAA 1TXUA 2OT3A 4OTTA 1GNIA 4L8UA 3LU8A 4F5VA 1E7GA 4OTUA 1MIYA 2I2ZA 3ICXA 3JRYA 2OZBB 2ROHA 5GINA 1H5WA 4G01A 3WHRA 5B5TA 3GA9L 4S1YA 4ZC6A 2BXAA 5GIOA 3H37A 2EFHA 2KBZA 4LB9A 4HGKA 4DHXB 5GHKA 2BXOA 2Z8JA 5DBYA 2BXQA 4FK5B 1N5UA 3FNMA 4F5SA 3NVKA 1E7IA 3M99C 4J2VA 4LUHA 2EFCA 4N3ZA 1MIVA 5IJ5A 1TF0A 4W4UB 2XSIA 1E78A 1E7EA 2BXIA 2CKXA 3H3AA 4Z9OA 2XW1A 2E0YA 1FOUA 4LA0A 1HK5A 4ZBQA 4BKEA 4IW2A 3NMUA 3G9KD 3GQXA 3VQIA 2XVVA 3WHQA 5FUOA 2BXKA 3MHHB 3KJLA 3SIVB 5D7GA 2QMCA 2XVWA 4G03A 3LU6A 3W1SA 2XW0A 3GQUA 4E99A 3V03A 4EMXA 1BKEA 3B9LA 5HOZA 4TQ1A 3FWBC 4HGMB 4LUFA 2Z8IA 4M70B 2BXHA 4PO0A 3UIVA 4C31B 2XVUA 1E7FA 1J7EA 3A75A 4FJCB 2BXMA 3A73A 4GDXA 1MIWA 4OR0A 2VUFA 4L9QA 2XMOA 4MBEC 5IFOA 1AO6A 4LB2A 1GNJA 1NT2B 1BM0A 1HA2A 4WA6B 5BPKA 4GDKB 3CX9A 1LNSA 4ZBKA 1HK1A 1JNBA 5IJEA 3WHSA 5IJFA 4G04A 1H9ZA 1KXPD 2BXGA 2I30A 3JQZA 4IW1A 1HK4A 4L9KA 3LU7A 2QHBA 1E7AA 2XVQA 2BXFA 4N0FD 2DBWA 3V09A 2DBXA 2YDFA 2NQOA 1IJGA 4F5TA 4TQ0A 1HK3A 1UORA 4GG2A 1O9XA 2BXLA 2V36A 1HK2A 5IIUA 4BY9C 2EFDA 2NNWA 3NVIA 3V08A 1KW2A 3NVMA 1J78A 2DBUA 4OT2A 3SIUB 1MA9A 2Z8KA 4NAWB 2BXBA 4ZUXV 4ZCGA 1E7HA 2VDBA 5ID7A 1BJ5A 1VZSA 2BXDA 4F5UA 2LOQA 3KIKA 5GIPA 2BX8A 2BXPA 2JUHA 2VUEA 4K2CA 5DQFA 2BXNA 1VFIA 3FWCC 3MHSB 1LOTA 2BXEA 4ZBRA 2DG5A 1E7BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DBW A;  2Z8J A;  2DBX A;  2Z8I A;  2NQO A;  3FNM A;  4GG2 A;  2V36 A;  2E0X A;  2QM6 A;  3A75 A;  4GDX A;  2DBU A;  4Z9O A;  2E0Y A;  4OTT A;  2Z8K A;  4ZCG A;  4OTU A;  3WHQ A;  5BPK A;  4ZBK A;  3WHS A;  2QMC A;  3WHR A;  5B5T A;  4ZC6 A;  2DG5 A; 
#chains in the Genus database with same CATH topology
 4GDL B;  2AJE A;  2DYO A;  5ID9 A;  5IIH A;  4Z69 A;  4FIP B;  4N0U D;  4K71 A;  3SQJ A;  2E0X A;  2QM6 A;  5IIX A;  2BXC A;  2LQI A;  2DYM A;  1E7C A;  2EFE A;  3B9M A;  4JK4 A;  3TDL A;  3ECP A;  3PLA A;  1TXU A;  2OT3 A;  4OTT A;  1GNI A;  4L8U A;  3LU8 A;  4F5V A;  1E7G A;  4OTU A;  1MIY A;  2AGH B;  2I2Z A;  3ICX A;  3JRY A;  2OZB B;  2ROH A;  5GIN A;  1H5W A;  4G01 A;  1MM8 A;  3WHR A;  5B5T A;  3GA9 L;  4S1Y A;  4ZC6 A;  2BXA A;  5GIO A;  3H37 A;  2EFH A;  2KBZ A;  4LB9 A;  4HGK A;  4DHX B;  5GHK A;  2BXO A;  2Z8J A;  5DBY A;  2BXQ A;  2LXT A;  4FK5 B;  1N5U A;  3FNM A;  4F5S A;  3NVK A;  1E7I A;  3M99 C;  4J2V A;  4LUH A;  2EFC A;  4N3Z A;  1MIV A;  5IJ5 A;  1TF0 A;  4W4U B;  2XSI A;  1E78 A;  1E7E A;  2BXI A;  2CKX A;  3H3A A;  4Z9O A;  2XW1 A;  2E0Y A;  1FOU A;  4LA0 A;  1HK5 A;  4ZBQ A;  4BKE A;  4D7X A;  4IW2 A;  3NMU A;  3G9K D;  3GQX A;  3VQI A;  2XVV A;  3WHQ A;  1MUH A;  5FUO A;  2BXK A;  3MHH B;  3KJL A;  3SIV B;  5D7G A;  2QMC A;  2XVW A;  4G03 A;  3LU6 A;  2K0N A;  2XW0 A;  3GQU A;  3W1S A;  3V03 A;  4E99 A;  4EMX A;  1MUS A;  1BKE A;  3B9L A;  5HOZ A;  4TQ1 A;  3FWB C;  4HGM B;  4LUF A;  2Z8I A;  2LXS A;  4M70 B;  2BXH A;  4PO0 A;  3UIV A;  1KDX A;  4C31 B;  2XVU A;  1E7F A;  1J7E A;  3A75 A;  4FJC B;  2BXM A;  3A73 A;  4GDX A;  1MIW A;  4I9O A;  4OR0 A;  2VUF A;  4L9Q A;  2XMO A;  4MBE C;  5IFO A;  1AO6 A;  4LB2 A;  1GNJ A;  1NT2 B;  1BM0 A;  1HA2 A;  4WA6 B;  2LQH A;  5BPK A;  4GDK B;  3CX9 A;  1LNS A;  4ZBK A;  1HK1 A;  1JNB A;  5IJE A;  3WHS A;  5IJF A;  4G04 A;  1H9Z A;  1KXP D;  2BXG A;  2I30 A;  3JQZ A;  4IW1 A;  1HK4 A;  4L9K A;  2GUT A;  3LU7 A;  2QHB A;  1E7A A;  2XVQ A;  2BXF A;  4N0F D;  2DBW A;  3V09 A;  2DBX A;  2YDF A;  2NQO A;  1IJG A;  4F5T A;  4TQ0 A;  1HK3 A;  1UOR A;  4GG2 A;  1O9X A;  2BXL A;  2V36 A;  1SB0 A;  1HK2 A;  5IIU A;  4BY9 C;  2EFD A;  2NNW A;  3NVI A;  3V08 A;  1KW2 A;  3NVM A;  1J78 A;  2DBU A;  4OT2 A;  4DM0 A;  1MA9 A;  3SIU B;  2Z8K A;  4NAW B;  2BXB A;  4ZUX V;  4ZCG A;  1E7H A;  2VDB A;  2KWF A;  3BPJ A;  1BJ5 A;  1VZS A;  2BXD A;  4F5U A;  2LOQ A;  3KIK A;  5ID7 A;  2BX8 A;  2BXP A;  2JUH A;  2VUE A;  4K2C A;  5DQF A;  5GIP A;  2BXN A;  1VFI A;  3FWC C;  3MHS B;  1LOT A;  2BXE A;  4ZBR A;  2DG5 A;  1E7B A; 
#chains in the Genus database with same CATH homology
 4GDL B;  2AJE A;  2DYO A;  5ID9 A;  5IIH A;  4Z69 A;  4FIP B;  4N0U D;  4K71 A;  3SQJ A;  2E0X A;  2QM6 A;  5IIX A;  2BXC A;  3TDL A;  2DYM A;  1E7C A;  2EFE A;  3B9M A;  4JK4 A;  3PLA A;  1TXU A;  2OT3 A;  4OTT A;  1GNI A;  4L8U A;  3LU8 A;  4F5V A;  1E7G A;  4OTU A;  1MIY A;  2I2Z A;  3ICX A;  3JRY A;  2OZB B;  2ROH A;  5GIN A;  1H5W A;  4G01 A;  3WHR A;  5B5T A;  3GA9 L;  4S1Y A;  4ZC6 A;  2BXA A;  5GIO A;  3H37 A;  2EFH A;  2KBZ A;  4LB9 A;  4HGK A;  4DHX B;  5GHK A;  2BXO A;  2Z8J A;  5DBY A;  2BXQ A;  4FK5 B;  1N5U A;  3FNM A;  4F5S A;  3NVK A;  1E7I A;  3M99 C;  4J2V A;  4LUH A;  2EFC A;  4N3Z A;  1MIV A;  5IJ5 A;  1TF0 A;  4W4U B;  2XSI A;  1E78 A;  1E7E A;  2BXI A;  2CKX A;  3H3A A;  4Z9O A;  2XW1 A;  2E0Y A;  1FOU A;  4LA0 A;  1HK5 A;  4ZBQ A;  4BKE A;  4IW2 A;  3NMU A;  3G9K D;  3GQX A;  3VQI A;  2XVV A;  3WHQ A;  5FUO A;  2BXK A;  3MHH B;  3KJL A;  3SIV B;  5D7G A;  2QMC A;  2XVW A;  4G03 A;  3LU6 A;  3W1S A;  2XW0 A;  3GQU A;  4E99 A;  3V03 A;  4EMX A;  1BKE A;  3B9L A;  5HOZ A;  4TQ1 A;  3FWB C;  4HGM B;  4LUF A;  2Z8I A;  4M70 B;  2BXH A;  4PO0 A;  3UIV A;  4C31 B;  2XVU A;  1E7F A;  1J7E A;  3A75 A;  4FJC B;  2BXM A;  3A73 A;  4GDX A;  1MIW A;  4OR0 A;  2VUF A;  4L9Q A;  2XMO A;  4MBE C;  5IFO A;  1AO6 A;  4LB2 A;  1GNJ A;  1NT2 B;  1BM0 A;  1HA2 A;  4WA6 B;  5BPK A;  4GDK B;  3CX9 A;  1LNS A;  4ZBK A;  1HK1 A;  1JNB A;  5IJE A;  3WHS A;  5IJF A;  4G04 A;  1H9Z A;  1KXP D;  2BXG A;  2I30 A;  3JQZ A;  4IW1 A;  1HK4 A;  4L9K A;  3LU7 A;  2QHB A;  1E7A A;  2XVQ A;  2BXF A;  4N0F D;  2DBW A;  3V09 A;  2DBX A;  2YDF A;  2NQO A;  1IJG A;  4F5T A;  4TQ0 A;  1HK3 A;  1UOR A;  4GG2 A;  1O9X A;  2BXL A;  2V36 A;  1HK2 A;  5IIU A;  4BY9 C;  2EFD A;  2NNW A;  3NVI A;  3V08 A;  1KW2 A;  3NVM A;  1J78 A;  2DBU A;  4OT2 A;  3SIU B;  1MA9 A;  2Z8K A;  4NAW B;  2BXB A;  4ZUX V;  4ZCG A;  1E7H A;  2VDB A;  5ID7 A;  1BJ5 A;  1VZS A;  2BXD A;  4F5U A;  2LOQ A;  3KIK A;  5GIP A;  2BX8 A;  2BXP A;  2JUH A;  2VUE A;  4K2C A;  5DQF A;  2BXN A;  1VFI A;  3FWC C;  3MHS B;  1LOT A;  2BXE A;  4ZBR A;  2DG5 A;  1E7B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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