2DBWA

Crystal structure of gamma-glutamyltranspeptidase from escherichia coli acyl-enzyme intermediate
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
359
structure length
359
Chain Sequence
APPVSYGVEEDVFHPVRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of gamma-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli k12
molecule keywords Gamma-glutamyltranspeptidase
total genus 100
structure length 359
sequence length 359
chains with identical sequence C
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2005-12-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2dbwA02
5BPKA 4GDXA 4ZBKA 2DBUA 2DG5A 2Z8JA 2E0XA 2NQOA 4ZC6A 4OTTA 3FNMA 2V36A 4Z9OA 5B5TA 4ZCGA 2DBXA 3A75A 3WHSA 2E0YA 4GG2A 2Z8IA 3WHRA 2QMCA 2DBWA 2Z8KA 2QM6A 4OTUA 3WHQA
chains in the Genus database with same CATH superfamily
2YDFA 1MIVA 4ZBKA 4W4UB 1BJ5A 2EFHA 5IJFA 1AO6A 3NVIA 4ZBRA 3V08A 3PLAA 2AGHB 2BXHA 2XVVA 5GIPA 4N0FD 4S1YA 3V03A 4F5UA 4GDKB 3TDLA 5ID7A 3CX9A 1JNBA 3MHHB 5GHKA 4NAWB 1MA9A 1J7EA 1MIYA 1O9XA 1E7IA 4G03A 3H3AA 5D7GA 1H5WA 5B5TA 5IIXA 3WHSA 2BXDA 1FOUA 2BXBA 2E0YA 3A73A 2JUHA 2QHBA 3SIVB 3SQJA 4LUFA 1HA2A 3ICXA 4G04A 1UORA 2XW0A 3V09A 3JRYA 4K2CA 2BXQA 2DYOA 2BX8A 3GQXA 3ECPA 2VUFA 4GDXA 5DBYA 2KWFA 4D7XA 4LA0A 2NNWA 4G01A 3FWCC 2BXKA 2BXNA 2AJEA 2EFDA 1GNIA 2E0XA 3B9LA 4LB9A 4LB2A 3KJLA 4M70B 4I9OA 3SIUB 4DHXB 2BXPA 2VUEA 1KXPD 3H37A 1HK2A 1E7CA 3GA9L 2BXLA 2VDBA 4F5SA 1LNSA 1TF0A 3LU8A 2ROHA 4FK5B 5IJ5A 4IW1A 1MUSA 3A75A 4DM0A 4LUHA 2LXSA 3GQUA 2K0NA 1E7BA 2QMCA 4TQ0A 2DBWA 2LQIA 5IIHA 2I30A 3NVMA 3LU7A 5IFOA 3W1SA 4ZBQA 1J78A 4OR0A 3BPJA 2LQHA 2OT3A 3LU6A 4HGMB 2BXCA 4MBEC 4F5TA 4Z69A 5GINA 3NVKA 3FWBC 1KDXA 5IJEA 4ZC6A 5ID9A 1E78A 1IJGA 2BXEA 3NMUA 2BXAA 4TQ1A 4PO0A 1VFIA 4Z9OA 4ZCGA 2BXMA 1N5UA 5DQFA 1SB0A 4L8UA 2GUTA 4FIPB 4GG2A 1NT2B 2LXTA 3WHRA 4K71A 4BY9C 1MUHA 2BXFA 2Z8KA 4OTUA 3M99C 4C31B 2LOQA 1E7HA 5BPKA 2BXGA 3KIKA 5HOZA 2XMOA 2EFCA 2DBUA 2BXIA 2I2ZA 2XSIA 1E7AA 2XVQA 4FJCB 4E99A 3MHSB 1KW2A 1HK5A 2DG5A 2Z8JA 5IIUA 1E7EA 2CKXA 1HK4A 2XW1A 4L9KA 1H9ZA 2NQOA 3JQZA 4N3ZA 3B9MA 3G9KD 4ZUXV 2KBZA 5GIOA 2EFEA 1E7FA 5FUOA 4HGKA 4OTTA 1BKEA 2XVUA 1BM0A 1MIWA 3FNMA 2V36A 1HK3A 4WA6B 2DBXA 4OT2A 1LOTA 2XVWA 1E7GA 1VZSA 4J2VA 1TXUA 4EMXA 2OZBB 1MM8A 1HK1A 4JK4A 4L9QA 3UIVA 2Z8IA 1GNJA 2BXOA 3VQIA 4F5VA 4N0UD 2QM6A 4IW2A 3WHQA 2DYMA 4BKEA 4GDLB
chains in the Genus database with same CATH topology
2YDFA 1MIVA 4ZBKA 4W4UB 1BJ5A 2EFHA 5IJFA 1AO6A 3NVIA 4ZBRA 3V08A 3PLAA 2BXHA 2XVVA 5GIPA 4N0FD 4S1YA 3V03A 4F5UA 4GDKB 3TDLA 5ID7A 3CX9A 1JNBA 3MHHB 5GHKA 4NAWB 1MA9A 1J7EA 1MIYA 1O9XA 1E7IA 4G03A 3H3AA 5D7GA 1H5WA 5B5TA 5IIXA 3WHSA 2BXDA 1FOUA 2BXBA 2E0YA 3A73A 2JUHA 2QHBA 3SIVB 3SQJA 4LUFA 1HA2A 3ICXA 4G04A 1UORA 2XW0A 3V09A 3JRYA 4K2CA 2BXQA 2DYOA 2BX8A 3GQXA 2VUFA 4GDXA 5DBYA 4LA0A 2NNWA 4G01A 3FWCC 2BXKA 2BXNA 2AJEA 2E0XA 1GNIA 2EFDA 3B9LA 4LB9A 4LB2A 3KJLA 4M70B 3SIUB 4DHXB 2BXPA 2VUEA 1KXPD 3H37A 1HK2A 1E7CA 3GA9L 2BXLA 2VDBA 4F5SA 1LNSA 1TF0A 3LU8A 2ROHA 4FK5B 5IJ5A 4IW1A 3A75A 4LUHA 3GQUA 1E7BA 2QMCA 4TQ0A 2DBWA 5IIHA 2I30A 3NVMA 3LU7A 5IFOA 3W1SA 4ZBQA 1J78A 4OR0A 2OT3A 3LU6A 4HGMB 2BXCA 4MBEC 4F5TA 4Z69A 5GINA 3NVKA 3FWBC 5IJEA 4ZC6A 5ID9A 1E78A 1IJGA 2BXEA 3NMUA 2BXAA 4TQ1A 4PO0A 1VFIA 4Z9OA 4ZCGA 2BXMA 1N5UA 5DQFA 4L8UA 4FIPB 4GG2A 1NT2B 3WHRA 4K71A 4BY9C 2BXFA 2Z8KA 4OTUA 3M99C 4C31B 2LOQA 1E7HA 5BPKA 2BXGA 3KIKA 5HOZA 2XMOA 2EFCA 2DBUA 2BXIA 2I2ZA 2XSIA 1E7AA 2XVQA 4FJCB 4E99A 3MHSB 1KW2A 1HK5A 2DG5A 2Z8JA 5IIUA 1E7EA 2CKXA 1HK4A 2XW1A 4L9KA 1H9ZA 2NQOA 3JQZA 4N3ZA 3B9MA 3G9KD 4ZUXV 2KBZA 5GIOA 2EFEA 1E7FA 5FUOA 4HGKA 4OTTA 1BKEA 2XVUA 1BM0A 1MIWA 3FNMA 2V36A 1HK3A 4WA6B 2DBXA 4OT2A 1LOTA 2XVWA 1E7GA 1VZSA 4J2VA 1TXUA 4EMXA 2OZBB 1HK1A 4JK4A 4L9QA 3UIVA 2Z8IA 1GNJA 2BXOA 3VQIA 4F5VA 4N0UD 2QM6A 4IW2A 3WHQA 2DYMA 4BKEA 4GDLB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BPK A;  4GDX A;  4ZBK A;  2DBU A;  2DG5 A;  2Z8J A;  2E0X A;  2NQO A;  4ZC6 A;  4OTT A;  3FNM A;  2V36 A;  4Z9O A;  5B5T A;  4ZCG A;  2DBX A;  3A75 A;  3WHS A;  2E0Y A;  4GG2 A;  2Z8I A;  3WHR A;  2QMC A;  2DBW A;  2Z8K A;  2QM6 A;  4OTU A;  3WHQ A; 
#chains in the Genus database with same CATH topology
 2YDF A;  1MIV A;  4ZBK A;  4W4U B;  1BJ5 A;  2EFH A;  5IJF A;  1AO6 A;  3NVI A;  4ZBR A;  3V08 A;  3PLA A;  2AGH B;  2BXH A;  2XVV A;  5GIP A;  4N0F D;  4S1Y A;  3V03 A;  4F5U A;  4GDK B;  3TDL A;  5ID7 A;  3CX9 A;  1JNB A;  3MHH B;  5GHK A;  4NAW B;  1MA9 A;  1J7E A;  1MIY A;  1O9X A;  1E7I A;  4G03 A;  3H3A A;  5D7G A;  1H5W A;  5B5T A;  5IIX A;  3WHS A;  2BXD A;  1FOU A;  2BXB A;  2E0Y A;  3A73 A;  2JUH A;  2QHB A;  3SIV B;  3SQJ A;  4LUF A;  1HA2 A;  3ICX A;  4G04 A;  1UOR A;  2XW0 A;  3V09 A;  3JRY A;  4K2C A;  2BXQ A;  2DYO A;  2BX8 A;  3GQX A;  3ECP A;  2VUF A;  4GDX A;  5DBY A;  2KWF A;  4D7X A;  4LA0 A;  2NNW A;  4G01 A;  3FWC C;  2BXK A;  2BXN A;  2AJE A;  2EFD A;  1GNI A;  2E0X A;  3B9L A;  4LB9 A;  4LB2 A;  3KJL A;  4M70 B;  4I9O A;  3SIU B;  4DHX B;  2BXP A;  2VUE A;  1KXP D;  3H37 A;  1HK2 A;  1E7C A;  3GA9 L;  2BXL A;  2VDB A;  4F5S A;  1LNS A;  1TF0 A;  3LU8 A;  2ROH A;  4FK5 B;  5IJ5 A;  4IW1 A;  1MUS A;  3A75 A;  4DM0 A;  4LUH A;  2LXS A;  3GQU A;  2K0N A;  1E7B A;  2QMC A;  4TQ0 A;  2DBW A;  2LQI A;  5IIH A;  2I30 A;  3NVM A;  3LU7 A;  5IFO A;  3W1S A;  4ZBQ A;  1J78 A;  4OR0 A;  3BPJ A;  2LQH A;  2OT3 A;  3LU6 A;  4HGM B;  2BXC A;  4MBE C;  4F5T A;  4Z69 A;  5GIN A;  3NVK A;  3FWB C;  1KDX A;  5IJE A;  4ZC6 A;  5ID9 A;  1E78 A;  1IJG A;  2BXE A;  3NMU A;  2BXA A;  4TQ1 A;  4PO0 A;  1VFI A;  4Z9O A;  4ZCG A;  2BXM A;  1N5U A;  5DQF A;  1SB0 A;  4L8U A;  2GUT A;  4FIP B;  4GG2 A;  1NT2 B;  2LXT A;  3WHR A;  4K71 A;  4BY9 C;  1MUH A;  2BXF A;  2Z8K A;  4OTU A;  3M99 C;  4C31 B;  2LOQ A;  1E7H A;  5BPK A;  2BXG A;  3KIK A;  5HOZ A;  2XMO A;  2EFC A;  2DBU A;  2BXI A;  2I2Z A;  2XSI A;  1E7A A;  2XVQ A;  4FJC B;  4E99 A;  3MHS B;  1KW2 A;  1HK5 A;  2DG5 A;  2Z8J A;  5IIU A;  1E7E A;  2CKX A;  1HK4 A;  2XW1 A;  4L9K A;  1H9Z A;  2NQO A;  3JQZ A;  4N3Z A;  3B9M A;  3G9K D;  4ZUX V;  2KBZ A;  5GIO A;  2EFE A;  1E7F A;  5FUO A;  4HGK A;  4OTT A;  1BKE A;  2XVU A;  1BM0 A;  1MIW A;  3FNM A;  2V36 A;  1HK3 A;  4WA6 B;  2DBX A;  4OT2 A;  1LOT A;  2XVW A;  1E7G A;  1VZS A;  4J2V A;  1TXU A;  4EMX A;  2OZB B;  1MM8 A;  1HK1 A;  4JK4 A;  4L9Q A;  3UIV A;  2Z8I A;  1GNJ A;  2BXO A;  3VQI A;  4F5V A;  4N0U D;  2QM6 A;  4IW2 A;  3WHQ A;  2DYM A;  4BKE A;  4GDL B; 
#chains in the Genus database with same CATH homology
 2YDF A;  1MIV A;  4ZBK A;  4W4U B;  1BJ5 A;  2EFH A;  5IJF A;  1AO6 A;  3NVI A;  4ZBR A;  3V08 A;  3PLA A;  2BXH A;  2XVV A;  5GIP A;  4N0F D;  4S1Y A;  3V03 A;  4F5U A;  4GDK B;  3TDL A;  5ID7 A;  3CX9 A;  1JNB A;  3MHH B;  5GHK A;  4NAW B;  1MA9 A;  1J7E A;  1MIY A;  1O9X A;  1E7I A;  4G03 A;  3H3A A;  5D7G A;  1H5W A;  5B5T A;  5IIX A;  3WHS A;  2BXD A;  1FOU A;  2BXB A;  2E0Y A;  3A73 A;  2JUH A;  2QHB A;  3SIV B;  3SQJ A;  4LUF A;  1HA2 A;  3ICX A;  4G04 A;  1UOR A;  2XW0 A;  3V09 A;  3JRY A;  4K2C A;  2BXQ A;  2DYO A;  2BX8 A;  3GQX A;  2VUF A;  4GDX A;  5DBY A;  4LA0 A;  2NNW A;  4G01 A;  3FWC C;  2BXK A;  2BXN A;  2AJE A;  2E0X A;  1GNI A;  2EFD A;  3B9L A;  4LB9 A;  4LB2 A;  3KJL A;  4M70 B;  3SIU B;  4DHX B;  2BXP A;  2VUE A;  1KXP D;  3H37 A;  1HK2 A;  1E7C A;  3GA9 L;  2BXL A;  2VDB A;  4F5S A;  1LNS A;  1TF0 A;  3LU8 A;  2ROH A;  4FK5 B;  5IJ5 A;  4IW1 A;  3A75 A;  4LUH A;  3GQU A;  1E7B A;  2QMC A;  4TQ0 A;  2DBW A;  5IIH A;  2I30 A;  3NVM A;  3LU7 A;  5IFO A;  3W1S A;  4ZBQ A;  1J78 A;  4OR0 A;  2OT3 A;  3LU6 A;  4HGM B;  2BXC A;  4MBE C;  4F5T A;  4Z69 A;  5GIN A;  3NVK A;  3FWB C;  5IJE A;  4ZC6 A;  5ID9 A;  1E78 A;  1IJG A;  2BXE A;  3NMU A;  2BXA A;  4TQ1 A;  4PO0 A;  1VFI A;  4Z9O A;  4ZCG A;  2BXM A;  1N5U A;  5DQF A;  4L8U A;  4FIP B;  4GG2 A;  1NT2 B;  3WHR A;  4K71 A;  4BY9 C;  2BXF A;  2Z8K A;  4OTU A;  3M99 C;  4C31 B;  2LOQ A;  1E7H A;  5BPK A;  2BXG A;  3KIK A;  5HOZ A;  2XMO A;  2EFC A;  2DBU A;  2BXI A;  2I2Z A;  2XSI A;  1E7A A;  2XVQ A;  4FJC B;  4E99 A;  3MHS B;  1KW2 A;  1HK5 A;  2DG5 A;  2Z8J A;  5IIU A;  1E7E A;  2CKX A;  1HK4 A;  2XW1 A;  4L9K A;  1H9Z A;  2NQO A;  3JQZ A;  4N3Z A;  3B9M A;  3G9K D;  4ZUX V;  2KBZ A;  5GIO A;  2EFE A;  1E7F A;  5FUO A;  4HGK A;  4OTT A;  1BKE A;  2XVU A;  1BM0 A;  1MIW A;  3FNM A;  2V36 A;  1HK3 A;  4WA6 B;  2DBX A;  4OT2 A;  1LOT A;  2XVW A;  1E7G A;  1VZS A;  4J2V A;  1TXU A;  4EMX A;  2OZB B;  1HK1 A;  4JK4 A;  4L9Q A;  3UIV A;  2Z8I A;  1GNJ A;  2BXO A;  3VQI A;  4F5V A;  4N0U D;  2QM6 A;  4IW2 A;  3WHQ A;  2DYM A;  4BKE A;  4GDL B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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