2DG5A

Crystal structure of gamma-glutamyl transpeptidase from escherichia coli in complex with hydrolyzed glutathione
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
351
structure length
351
Chain Sequence
EEDVFHPVRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of gamma-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli k12
molecule keywords Gamma-glutamyltranspeptidase
total genus 97
structure length 351
sequence length 351
chains with identical sequence C
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2006-03-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2dg5A02
2V36A 2Z8IA 4ZCGA 3WHQA 3WHSA 4OTTA 2QMCA 2DBWA 2DBXA 4Z9OA 3A75A 4GDXA 2DBUA 2Z8JA 2DG5A 5BPKA 4ZC6A 4ZBKA 2E0XA 2Z8KA 3WHRA 2NQOA 2E0YA 3FNMA 4OTUA 2QM6A 5B5TA 4GG2A
chains in the Genus database with same CATH superfamily
5GIOA 1E7GA 4ZCGA 3V03A 1BJ5A 2YDFA 3G9KD 5IFOA 2DYOA 5DBYA 1HK4A 3NVMA 2QMCA 1LOTA 4F5SA 4WA6B 2JUHA 3MHSB 4LB2A 4FIPB 2ROHA 2DBUA 4L9KA 1TF0A 4LUHA 3NMUA 5GIPA 3NVKA 2DG5A 2BXMA 4W4UB 3PLAA 1TXUA 5IIXA 2XMOA 5GINA 3WHRA 1E7HA 3A73A 1JNBA 1HK3A 2EFDA 2OZBB 4ZUXV 2XW0A 2E0YA 1N5UA 1GNJA 2OT3A 3FNMA 3GA9L 4FJCB 4M70B 2EFCA 1HA2A 2BXPA 2LQIA 5IIHA 1MA9A 3KIKA 2EFEA 4GG2A 1BKEA 2V36A 2Z8IA 1SB0A 4K71A 1MUHA 3M99C 3WHSA 2KBZA 2K0NA 2LXSA 3H3AA 4HGKA 4OTTA 4S1YA 1MIWA 1KXPD 4I9OA 3GQUA 4TQ1A 5GHKA 4DM0A 1HK1A 4F5VA 1E7FA 2VDBA 2LOQA 2NNWA 2XVWA 4MBEC 4Z9OA 4ZBQA 5FUOA 3A75A 1O9XA 4GDXA 3MHHB 1E7BA 2QHBA 4N0FD 2LQHA 4G01A 4ZC6A 5IIUA 1MUSA 2E0XA 2Z8KA 2BXOA 2I2ZA 3FWBC 4HGMB 2KWFA 4E99A 4JK4A 1HK2A 3JQZA 1E7IA 1J7EA 1E7CA 1UORA 3BPJA 2BXDA 2BXQA 1MM8A 4IW2A 3ICXA 5DQFA 3FWCC 3NVIA 2DBWA 2VUEA 2BXIA 5BPKA 1E7AA 3KJLA 4GDKB 4F5UA 1FOUA 5IJEA 2BXNA 1LNSA 3SIVB 3WHQA 1H9ZA 5IJ5A 4TQ0A 1E78A 3LU8A 1KW2A 3V08A 2XVUA 3LU6A 2BXKA 5ID7A 4N3ZA 2BXCA 3LU7A 4FK5B 3B9MA 2EFHA 4Z69A 2BXBA 3SIUB 2BXAA 1E7EA 4L8UA 4GDLB 2XVVA 4J2VA 2NQOA 4LUFA 3ECPA 2GUTA 1GNIA 4G03A 1MIVA 2BXFA 4LA0A 1BM0A 2DYMA 1IJGA 4OTUA 2XSIA 1H5WA 2AGHB 4F5TA 5B5TA 3TDLA 2BXGA 3H37A 3SQJA 4DHXB 3UIVA 4LB9A 4G04A 4PO0A 4BKEA 3B9LA 4OT2A 5D7GA 3VQIA 3V09A 4K2CA 2CKXA 4ZBRA 2DBXA 1NT2B 2LXTA 1VZSA 2BXEA 4L9QA 4BY9C 2VUFA 5HOZA 5ID9A 1MIYA 4C31B 2Z8JA 4N0UD 1VFIA 1HK5A 2XVQA 4EMXA 2I30A 3GQXA 4ZBKA 1KDXA 2XW1A 2BXLA 2BXHA 5IJFA 4IW1A 2BX8A 3CX9A 4NAWB 2AJEA 3W1SA 4D7XA 1AO6A 3JRYA 1J78A 4OR0A 2QM6A
chains in the Genus database with same CATH topology
5GIOA 1E7GA 4ZCGA 3V03A 1BJ5A 2YDFA 3G9KD 5IFOA 2DYOA 5DBYA 1HK4A 3NVMA 2QMCA 1LOTA 4F5SA 4WA6B 2JUHA 3MHSB 4LB2A 4FIPB 2ROHA 2DBUA 4L9KA 1TF0A 4LUHA 3NMUA 5GIPA 3NVKA 2DG5A 2BXMA 4W4UB 3PLAA 1TXUA 5IIXA 2XMOA 5GINA 3WHRA 1E7HA 3A73A 1JNBA 1HK3A 2EFDA 2OZBB 4ZUXV 2XW0A 2E0YA 1N5UA 1GNJA 2OT3A 3FNMA 3GA9L 4FJCB 4M70B 2EFCA 1HA2A 2BXPA 5IIHA 1MA9A 3KIKA 2EFEA 4GG2A 1BKEA 2V36A 2Z8IA 4K71A 3M99C 3WHSA 2KBZA 3H3AA 4HGKA 4OTTA 4S1YA 3NVIA 5GHKA 1MIWA 1KXPD 4TQ1A 3GQUA 1HK1A 4F5VA 1E7FA 2VDBA 2LOQA 2NNWA 2XVWA 4MBEC 4Z9OA 4ZBQA 5FUOA 3A75A 1O9XA 4GDXA 3MHHB 1E7BA 2QHBA 4N0FD 4G01A 4ZC6A 5IIUA 2E0XA 2Z8KA 2BXOA 2I2ZA 3FWBC 4HGMB 4E99A 4JK4A 1HK2A 3JQZA 1E7IA 1J7EA 1E7CA 1UORA 2BXDA 2BXQA 4IW2A 3ICXA 5DQFA 3FWCC 2DBWA 2VUEA 2BXIA 5BPKA 1E7AA 3KJLA 4GDKB 4F5UA 1FOUA 5IJEA 2BXNA 1LNSA 3SIVB 3WHQA 1H9ZA 5IJ5A 4TQ0A 1E78A 3LU8A 1KW2A 3V08A 2XVUA 3LU6A 2BXKA 5ID7A 4N3ZA 2BXCA 3LU7A 4FK5B 3B9MA 2EFHA 4Z69A 2BXBA 3SIUB 2BXAA 1E7EA 4L8UA 4GDLB 2XVVA 4J2VA 2NQOA 4LUFA 1GNIA 4G03A 1MIVA 2BXFA 4LA0A 1BM0A 2DYMA 1IJGA 4OTUA 2XSIA 1H5WA 4F5TA 5B5TA 3TDLA 2BXGA 3H37A 3SQJA 4DHXB 3UIVA 4LB9A 4G04A 4PO0A 4BKEA 3B9LA 4OT2A 5D7GA 3VQIA 3V09A 4K2CA 2CKXA 4ZBRA 2DBXA 1NT2B 1VZSA 2BXEA 4L9QA 4BY9C 2VUFA 5HOZA 5ID9A 1MIYA 4C31B 2Z8JA 4N0UD 1VFIA 1HK5A 2XVQA 4EMXA 2I30A 3GQXA 4ZBKA 2XW1A 2BXLA 2BXHA 5IJFA 4IW1A 2BX8A 3CX9A 4NAWB 2AJEA 3W1SA 1AO6A 3JRYA 1J78A 4OR0A 2QM6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V36 A;  2Z8I A;  4ZCG A;  3WHQ A;  3WHS A;  4OTT A;  2QMC A;  2DBW A;  2DBX A;  4Z9O A;  3A75 A;  4GDX A;  2DBU A;  2Z8J A;  2DG5 A;  5BPK A;  4ZC6 A;  4ZBK A;  2E0X A;  2Z8K A;  3WHR A;  2NQO A;  2E0Y A;  3FNM A;  4OTU A;  2QM6 A;  5B5T A;  4GG2 A; 
#chains in the Genus database with same CATH topology
 5GIO A;  1E7G A;  4ZCG A;  3V03 A;  1BJ5 A;  2YDF A;  3G9K D;  5IFO A;  2DYO A;  5DBY A;  1HK4 A;  3NVM A;  2QMC A;  1LOT A;  4F5S A;  4WA6 B;  2JUH A;  3MHS B;  4LB2 A;  4FIP B;  2ROH A;  2DBU A;  4L9K A;  1TF0 A;  4LUH A;  3NMU A;  5GIP A;  3NVK A;  2DG5 A;  2BXM A;  4W4U B;  3PLA A;  1TXU A;  5IIX A;  2XMO A;  5GIN A;  3WHR A;  1E7H A;  3A73 A;  1JNB A;  1HK3 A;  2EFD A;  2OZB B;  4ZUX V;  2XW0 A;  2E0Y A;  1N5U A;  1GNJ A;  2OT3 A;  3FNM A;  3GA9 L;  4FJC B;  4M70 B;  2EFC A;  1HA2 A;  2BXP A;  2LQI A;  5IIH A;  1MA9 A;  3KIK A;  2EFE A;  4GG2 A;  1BKE A;  2V36 A;  2Z8I A;  1SB0 A;  4K71 A;  1MUH A;  3M99 C;  3WHS A;  2KBZ A;  2K0N A;  2LXS A;  3H3A A;  4HGK A;  4OTT A;  4S1Y A;  1MIW A;  1KXP D;  4I9O A;  3GQU A;  4TQ1 A;  5GHK A;  4DM0 A;  1HK1 A;  4F5V A;  1E7F A;  2VDB A;  2LOQ A;  2NNW A;  2XVW A;  4MBE C;  4Z9O A;  4ZBQ A;  5FUO A;  3A75 A;  1O9X A;  4GDX A;  3MHH B;  1E7B A;  2QHB A;  4N0F D;  2LQH A;  4G01 A;  4ZC6 A;  5IIU A;  1MUS A;  2E0X A;  2Z8K A;  2BXO A;  2I2Z A;  3FWB C;  4HGM B;  2KWF A;  4E99 A;  4JK4 A;  1HK2 A;  3JQZ A;  1E7I A;  1J7E A;  1E7C A;  1UOR A;  3BPJ A;  2BXD A;  2BXQ A;  1MM8 A;  4IW2 A;  3ICX A;  5DQF A;  3FWC C;  3NVI A;  2DBW A;  2VUE A;  2BXI A;  5BPK A;  1E7A A;  3KJL A;  4GDK B;  4F5U A;  1FOU A;  5IJE A;  2BXN A;  1LNS A;  3SIV B;  3WHQ A;  1H9Z A;  5IJ5 A;  4TQ0 A;  1E78 A;  3LU8 A;  1KW2 A;  3V08 A;  2XVU A;  3LU6 A;  2BXK A;  5ID7 A;  4N3Z A;  2BXC A;  3LU7 A;  4FK5 B;  3B9M A;  2EFH A;  4Z69 A;  2BXB A;  3SIU B;  2BXA A;  1E7E A;  4L8U A;  4GDL B;  2XVV A;  4J2V A;  2NQO A;  4LUF A;  3ECP A;  2GUT A;  1GNI A;  4G03 A;  1MIV A;  2BXF A;  4LA0 A;  1BM0 A;  2DYM A;  1IJG A;  4OTU A;  2XSI A;  1H5W A;  2AGH B;  4F5T A;  5B5T A;  3TDL A;  2BXG A;  3H37 A;  3SQJ A;  4DHX B;  3UIV A;  4LB9 A;  4G04 A;  4PO0 A;  4BKE A;  3B9L A;  4OT2 A;  5D7G A;  3VQI A;  3V09 A;  4K2C A;  2CKX A;  4ZBR A;  2DBX A;  1NT2 B;  2LXT A;  1VZS A;  2BXE A;  4L9Q A;  4BY9 C;  2VUF A;  5HOZ A;  5ID9 A;  1MIY A;  4C31 B;  2Z8J A;  4N0U D;  1VFI A;  1HK5 A;  2XVQ A;  4EMX A;  2I30 A;  3GQX A;  4ZBK A;  1KDX A;  2XW1 A;  2BXL A;  2BXH A;  5IJF A;  4IW1 A;  2BX8 A;  3CX9 A;  4NAW B;  2AJE A;  3W1S A;  4D7X A;  1AO6 A;  3JRY A;  1J78 A;  4OR0 A;  2QM6 A; 
#chains in the Genus database with same CATH homology
 5GIO A;  1E7G A;  4ZCG A;  3V03 A;  1BJ5 A;  2YDF A;  3G9K D;  5IFO A;  2DYO A;  5DBY A;  1HK4 A;  3NVM A;  2QMC A;  1LOT A;  4F5S A;  4WA6 B;  2JUH A;  3MHS B;  4LB2 A;  4FIP B;  2ROH A;  2DBU A;  4L9K A;  1TF0 A;  4LUH A;  3NMU A;  5GIP A;  3NVK A;  2DG5 A;  2BXM A;  4W4U B;  3PLA A;  1TXU A;  5IIX A;  2XMO A;  5GIN A;  3WHR A;  1E7H A;  3A73 A;  1JNB A;  1HK3 A;  2EFD A;  2OZB B;  4ZUX V;  2XW0 A;  2E0Y A;  1N5U A;  1GNJ A;  2OT3 A;  3FNM A;  3GA9 L;  4FJC B;  4M70 B;  2EFC A;  1HA2 A;  2BXP A;  5IIH A;  1MA9 A;  3KIK A;  2EFE A;  4GG2 A;  1BKE A;  2V36 A;  2Z8I A;  4K71 A;  3M99 C;  3WHS A;  2KBZ A;  3H3A A;  4HGK A;  4OTT A;  4S1Y A;  3NVI A;  5GHK A;  1MIW A;  1KXP D;  4TQ1 A;  3GQU A;  1HK1 A;  4F5V A;  1E7F A;  2VDB A;  2LOQ A;  2NNW A;  2XVW A;  4MBE C;  4Z9O A;  4ZBQ A;  5FUO A;  3A75 A;  1O9X A;  4GDX A;  3MHH B;  1E7B A;  2QHB A;  4N0F D;  4G01 A;  4ZC6 A;  5IIU A;  2E0X A;  2Z8K A;  2BXO A;  2I2Z A;  3FWB C;  4HGM B;  4E99 A;  4JK4 A;  1HK2 A;  3JQZ A;  1E7I A;  1J7E A;  1E7C A;  1UOR A;  2BXD A;  2BXQ A;  4IW2 A;  3ICX A;  5DQF A;  3FWC C;  2DBW A;  2VUE A;  2BXI A;  5BPK A;  1E7A A;  3KJL A;  4GDK B;  4F5U A;  1FOU A;  5IJE A;  2BXN A;  1LNS A;  3SIV B;  3WHQ A;  1H9Z A;  5IJ5 A;  4TQ0 A;  1E78 A;  3LU8 A;  1KW2 A;  3V08 A;  2XVU A;  3LU6 A;  2BXK A;  5ID7 A;  4N3Z A;  2BXC A;  3LU7 A;  4FK5 B;  3B9M A;  2EFH A;  4Z69 A;  2BXB A;  3SIU B;  2BXA A;  1E7E A;  4L8U A;  4GDL B;  2XVV A;  4J2V A;  2NQO A;  4LUF A;  1GNI A;  4G03 A;  1MIV A;  2BXF A;  4LA0 A;  1BM0 A;  2DYM A;  1IJG A;  4OTU A;  2XSI A;  1H5W A;  4F5T A;  5B5T A;  3TDL A;  2BXG A;  3H37 A;  3SQJ A;  4DHX B;  3UIV A;  4LB9 A;  4G04 A;  4PO0 A;  4BKE A;  3B9L A;  4OT2 A;  5D7G A;  3VQI A;  3V09 A;  4K2C A;  2CKX A;  4ZBR A;  2DBX A;  1NT2 B;  1VZS A;  2BXE A;  4L9Q A;  4BY9 C;  2VUF A;  5HOZ A;  5ID9 A;  1MIY A;  4C31 B;  2Z8J A;  4N0U D;  1VFI A;  1HK5 A;  2XVQ A;  4EMX A;  2I30 A;  3GQX A;  4ZBK A;  2XW1 A;  2BXL A;  2BXH A;  5IJF A;  4IW1 A;  2BX8 A;  3CX9 A;  4NAW B;  2AJE A;  3W1S A;  1AO6 A;  3JRY A;  1J78 A;  4OR0 A;  2QM6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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