2LQHA

Nmr structure of foxo3a transactivation domains (cr2c-cr3) in complex with cbp kix domain (2b3l conformation)
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
87
structure length
87
Chain Sequence
GVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords CREB-binding protein
total genus 33
structure length 87
sequence length 87
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2012-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02172 KIX KIX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.20 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Coactivator CBP, KIX domain 2lqhA00
2AGHB 2LQIA 2LXTA 2LQHA 2KWFA 2LXSA 2K0NA 4D7XA 4I9OA 1KDXA 1SB0A 2GUTA
chains in the Genus database with same CATH superfamily
4G03A 4ZBKA 3GQXA 4F5SA 5D7GA 1MA9A 3CX9A 4OT2A 3WHSA 4N0FD 2XVQA 2BXAA 3A73A 4W4UB 1AO6A 3GQUA 3M99C 5DQFA 3W1SA 3NVMA 2LQIA 4LB2A 2QM6A 2LQHA 5GIOA 4ZC6A 2E0XA 2CKXA 3JRYA 4EMXA 5IJEA 2JUHA 2DYOA 1BJ5A 4I9OA 4LA0A 1E7AA 3G9KD 2BXEA 2EFHA 4HGKA 3SQJA 2NQOA 3UIVA 1E7HA 4LUHA 3PLAA 1LOTA 3JQZA 1HK3A 3ECPA 1HK4A 1KXPD 1VZSA 2XVUA 2VUEA 2YDFA 4K71A 4DHXB 2VDBA 4ZBRA 1E7BA 4Z9OA 1BKEA 2V36A 3LU7A 1GNIA 2DYMA 2I2ZA 1VFIA 2BXOA 2XW1A 1MIYA 5IIHA 2NNWA 4L8UA 4ZUXV 2OT3A 1TF0A 3KIKA 4J2VA 3H37A 1J78A 1GNJA 2AGHB 2BXFA 3NMUA 1UORA 2BXBA 4HGMB 4K2CA 4N0UD 2I30A 2LXSA 2BXNA 4ZCGA 2Z8JA 4LUFA 2AJEA 3V09A 2BXLA 4TQ0A 1JNBA 5BPKA 2BXKA 1N5UA 2LOQA 3SIVB 5ID7A 4M70B 4GDKB 5DBYA 3ICXA 2ROHA 3B9LA 4WA6B 4JK4A 4MBEC 3NVIA 4F5VA 1HA2A 1BM0A 1E7GA 1LNSA 2KBZA 2XMOA 3H3AA 1KW2A 2XW0A 2Z8IA 3KJLA 3WHQA 3V08A 2DG5A 3B9MA 5GINA 1E7EA 3FWCC 2XVWA 1MUSA 2K0NA 4D7XA 5IFOA 2QMCA 5IIXA 1SB0A 2BXDA 3GA9L 4L9KA 5IJ5A 4GG2A 3MHSB 2BXGA 1MM8A 3LU8A 1O9XA 4G01A 2E0YA 4F5TA 4BKEA 2EFDA 2BXCA 1FOUA 4Z69A 1MUHA 1HK5A 3WHRA 2DBWA 4C31B 4BY9C 1E7IA 2DBUA 2BXMA 2BXPA 4FIPB 1H5WA 4OTTA 3SIUB 3BPJA 1HK2A 2QHBA 4L9QA 4IW1A 4G04A 3A75A 3TDLA 4TQ1A 3LU6A 5IIUA 1HK1A 2BXHA 3VQIA 3FWBC 5FUOA 1H9ZA 1NT2B 5B5TA 2OZBB 4PO0A 4GDLB 4IW2A 2DBXA 4E99A 4LB9A 5GIPA 4DM0A 2LXTA 1E7FA 4OTUA 2EFCA 3NVKA 1IJGA 2BXQA 4F5UA 4S1YA 1KDXA 1MIWA 3MHHB 2BXIA 4N3ZA 2VUFA 4NAWB 2EFEA 4OR0A 5IJFA 1MIVA 3FNMA 5HOZA 4FJCB 5ID9A 2XSIA 2BX8A 4FK5B 1E78A 2Z8KA 1J7EA 5GHKA 2XVVA 4GDXA 2KWFA 4ZBQA 3V03A 1E7CA 1TXUA 2GUTA
chains in the Genus database with same CATH topology
2AGHB 2LQIA 2LXTA 2LQHA 2KWFA 2LXSA 2K0NA 4D7XA 4I9OA 1KDXA 1SB0A 2GUTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AGH B;  2LQI A;  2LXT A;  2LQH A;  2KWF A;  2LXS A;  2K0N A;  4D7X A;  4I9O A;  1KDX A;  1SB0 A;  2GUT A; 
#chains in the Genus database with same CATH topology
 4G03 A;  4ZBK A;  3GQX A;  4F5S A;  5D7G A;  1MA9 A;  3CX9 A;  4OT2 A;  3WHS A;  4N0F D;  2XVQ A;  2BXA A;  3A73 A;  4W4U B;  1AO6 A;  3GQU A;  3M99 C;  5DQF A;  3W1S A;  3NVM A;  2LQI A;  4LB2 A;  2QM6 A;  2LQH A;  5GIO A;  4ZC6 A;  2E0X A;  2CKX A;  3JRY A;  4EMX A;  5IJE A;  2JUH A;  2DYO A;  1BJ5 A;  4I9O A;  4LA0 A;  1E7A A;  3G9K D;  2BXE A;  2EFH A;  4HGK A;  3SQJ A;  2NQO A;  3UIV A;  1E7H A;  4LUH A;  3PLA A;  1LOT A;  3JQZ A;  1HK3 A;  3ECP A;  1HK4 A;  1KXP D;  1VZS A;  2XVU A;  2VUE A;  2YDF A;  4K71 A;  4DHX B;  2VDB A;  4ZBR A;  1E7B A;  4Z9O A;  1BKE A;  2V36 A;  3LU7 A;  1GNI A;  2DYM A;  2I2Z A;  1VFI A;  2BXO A;  2XW1 A;  1MIY A;  5IIH A;  2NNW A;  4L8U A;  4ZUX V;  2OT3 A;  1TF0 A;  3KIK A;  4J2V A;  3H37 A;  1J78 A;  1GNJ A;  2AGH B;  2BXF A;  3NMU A;  1UOR A;  2BXB A;  4HGM B;  4K2C A;  4N0U D;  2I30 A;  2LXS A;  2BXN A;  4ZCG A;  2Z8J A;  4LUF A;  2AJE A;  3V09 A;  2BXL A;  4TQ0 A;  1JNB A;  5BPK A;  2BXK A;  1N5U A;  2LOQ A;  3SIV B;  5ID7 A;  4M70 B;  4GDK B;  5DBY A;  3ICX A;  2ROH A;  3B9L A;  4WA6 B;  4JK4 A;  4MBE C;  3NVI A;  4F5V A;  1HA2 A;  1BM0 A;  1E7G A;  1LNS A;  2KBZ A;  2XMO A;  3H3A A;  1KW2 A;  2XW0 A;  2Z8I A;  3KJL A;  3WHQ A;  3V08 A;  2DG5 A;  3B9M A;  5GIN A;  1E7E A;  3FWC C;  2XVW A;  1MUS A;  2K0N A;  4D7X A;  5IFO A;  2QMC A;  5IIX A;  1SB0 A;  2BXD A;  3GA9 L;  4L9K A;  5IJ5 A;  4GG2 A;  3MHS B;  2BXG A;  1MM8 A;  3LU8 A;  1O9X A;  4G01 A;  2E0Y A;  4F5T A;  4BKE A;  2EFD A;  2BXC A;  1FOU A;  4Z69 A;  1MUH A;  1HK5 A;  3WHR A;  2DBW A;  4C31 B;  4BY9 C;  1E7I A;  2DBU A;  2BXM A;  2BXP A;  4FIP B;  1H5W A;  4OTT A;  3SIU B;  3BPJ A;  1HK2 A;  2QHB A;  4L9Q A;  4IW1 A;  4G04 A;  3A75 A;  3TDL A;  4TQ1 A;  3LU6 A;  5IIU A;  1HK1 A;  2BXH A;  3VQI A;  3FWB C;  5FUO A;  1H9Z A;  1NT2 B;  5B5T A;  2OZB B;  4PO0 A;  4GDL B;  4IW2 A;  2DBX A;  4E99 A;  4LB9 A;  5GIP A;  4DM0 A;  2LXT A;  1E7F A;  4OTU A;  2EFC A;  3NVK A;  1IJG A;  2BXQ A;  4F5U A;  4S1Y A;  1KDX A;  1MIW A;  3MHH B;  2BXI A;  4N3Z A;  2VUF A;  4NAW B;  2EFE A;  4OR0 A;  5IJF A;  1MIV A;  3FNM A;  5HOZ A;  4FJC B;  5ID9 A;  2XSI A;  2BX8 A;  4FK5 B;  1E78 A;  2Z8K A;  1J7E A;  5GHK A;  2XVV A;  4GDX A;  2KWF A;  4ZBQ A;  3V03 A;  1E7C A;  1TXU A;  2GUT A; 
#chains in the Genus database with same CATH homology
 2AGH B;  2LQI A;  2LXT A;  2LQH A;  2KWF A;  2LXS A;  2K0N A;  4D7X A;  4I9O A;  1KDX A;  1SB0 A;  2GUT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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