3A73A

Crystal structure analysis of human serum albumin complexed with delta 12-prostaglandin j2
Total Genus 222
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
222
sequence length
583
structure length
576
Chain Sequence
AHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Delta12-prostaglandin J2 as a product and ligand of human serum albumin: formation of an unusual covalent adduct at His146.
pubmed doi rcsb
molecule tags Lipid binding protein
molecule keywords Serum albumin
total genus 222
structure length 576
sequence length 583
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-09-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A05
4BKEA 2BXAA 4F5SA 1HK5A 1HA2A 1HK2A 4N0UD 3B9LA 5IFOA 3LU7A 2BXNA 1BM0A 1N5UA 2XSIA 4OT2A 4L8UA 3LU8A 4Z69A 4K2CA 3UIVA 5HOZA 5IIUA 2XVUA 5ID7A 4E99A 4G04A 2BX8A 1E7IA 3JQZA 2BXMA 1TF0A 1KW2A 2BXLA 2BXBA 2XW1A 4J2VA 2BXQA 1E7AA 4LA0A 4S1YA 4F5VA 4IW1A 1LOTA 1E7EA 2BXKA 3B9MA 4EMXA 5DQFA 5IJEA 1E7BA 4G03A 3TDLA 1J7EA 1GNIA 3V09A 4IW2A 4LUFA 1KXPD 3V03A 2I2ZA 5IJ5A 4F5TA 3LU6A 3JRYA 4HGMB 3SQJA 5ID9A 4JK4A 1E78A 4L9QA 4LB9A 1HK3A 4N0FD 1J78A 2VUFA 1E7CA 3CX9A 5DBYA 1AO6A 2VUEA 3V08A 4K71A 1GNJA 2YDFA 1E7GA 4F5UA 2VDBA 2XVWA 2BXFA 4L9KA 1MA9A 2BXPA 2XVVA 5IIHA 5IJFA 4OR0A 1UORA 1HK4A 1E7HA 2BXDA 3A73A 2BXEA 4ZBQA 5GHKA 1BJ5A 2XW0A 2BXGA 1E7FA 1O9XA 4ZBRA 4HGKA 1BKEA 4LUHA 2BXHA 4PO0A 2BXIA 5IIXA 1HK1A 2I30A 5FUOA 1H9ZA 4LB2A 2XVQA 2BXOA 2BXCA
chains in the Genus database with same CATH superfamily
4BKEA 2BXAA 4BY9C 3SIUB 1LNSA 4F5SA 2QMCA 4NAWB 1HK5A 1HA2A 2DG5A 2NNWA 4M70B 1VZSA 1HK2A 4N0UD 3B9LA 5IFOA 3NVKA 2DBWA 1MUSA 2LXSA 3LU7A 2BXNA 5GIOA 1BM0A 4MBEC 4OTTA 1N5UA 3MHHB 2Z8JA 2QHBA 2KBZA 2Z8IA 2ROHA 2XSIA 4OT2A 3FNMA 2LQHA 4TQ0A 4L8UA 3LU8A 2K0NA 4GG2A 4Z69A 4TQ1A 4K2CA 3A75A 3UIVA 5HOZA 5IIUA 2XVUA 5ID7A 3WHQA 1IJGA 3H3AA 4E99A 4G04A 2BX8A 1E7IA 4DM0A 2E0XA 2OT3A 2XVQA 3JQZA 2BXMA 4D7XA 2DBUA 1TF0A 3WHSA 2QM6A 4G01A 2LXTA 1KW2A 3KIKA 2NQOA 2BXLA 2BXBA 2V36A 2XW1A 4J2VA 2BXQA 4Z9OA 1E7AA 4LA0A 4C31B 1VFIA 4S1YA 3W1SA 3FWBC 4F5VA 1MUHA 4FJCB 4IW1A 4ZUXV 1LOTA 4WA6B 1E7EA 2BXKA 3B9MA 4EMXA 5DQFA 4ZCGA 5IJEA 1E7BA 4G03A 3TDLA 1J7EA 5GINA 1JNBA 2OZBB 1GNIA 2AGHB 3V09A 3NVIA 3ICXA 4IW2A 4LUFA 2EFHA 1KXPD 2EFDA 3V03A 4GDLB 2I2ZA 5IJ5A 4F5TA 2LOQA 3WHRA 3LU6A 4W4UB 4DHXB 1SB0A 1H5WA 3JRYA 4HGMB 4OTUA 3SQJA 3VQIA 5ID9A 2DYOA 1MIWA 3FWCC 3GA9L 2XMOA 5D7GA 3NMUA 3MHSB 4JK4A 2CKXA 3M99C 1E78A 2DYMA 3H37A 4L9QA 3KJLA 4LB9A 1HK3A 4N0FD 1J78A 3NVMA 2VUFA 1E7CA 3CX9A 5DBYA 1AO6A 2EFEA 2VUEA 4K71A 3V08A 2E0YA 2Z8KA 5BPKA 2YDFA 4GDXA 1E7GA 4FK5B 4ZC6A 2AJEA 4F5UA 2VDBA 2XVWA 2BXFA 4L9KA 1MA9A 2BXPA 2XVVA 2DBXA 1NT2B 3GQXA 5IIHA 5IJFA 2JUHA 4OR0A 1UORA 1HK4A 2EFCA 1E7HA 1MIYA 2BXDA 2BXEA 3A73A 4GDKB 4ZBKA 1MIVA 4ZBQA 5GHKA 3SIVB 1BJ5A 1TXUA 1KDXA 2XW0A 3GQUA 2BXGA 5B5TA 1E7FA 1O9XA 4N3ZA 3ECPA 4ZBRA 3BPJA 2GUTA 4HGKA 1BKEA 4LUHA 5GIPA 2BXHA 4PO0A 2BXIA 2KWFA 4I9OA 5IIXA 2LQIA 1HK1A 2I30A 5FUOA 1FOUA 4FIPB 1H9ZA 3PLAA 1MM8A 4LB2A 3G9KD 1GNJA 2BXOA 2BXCA
chains in the Genus database with same CATH topology
4BKEA 2BXAA 4BY9C 3SIUB 1LNSA 4F5SA 2QMCA 4NAWB 1HK5A 1HA2A 2DG5A 2NNWA 4M70B 1VZSA 1HK2A 4N0UD 3B9LA 5IFOA 3NVKA 2DBWA 3LU7A 2BXNA 5GIOA 1BM0A 4MBEC 4OTTA 1N5UA 3MHHB 2Z8JA 2QHBA 2KBZA 2Z8IA 2ROHA 2XSIA 4OT2A 3FNMA 4TQ0A 4L8UA 3LU8A 4GG2A 4Z69A 4TQ1A 4K2CA 3A75A 3UIVA 5HOZA 5IIUA 2XVUA 5ID7A 3WHQA 1IJGA 3H3AA 4E99A 4G04A 2BX8A 1E7IA 2E0XA 2OT3A 2XVQA 3JQZA 2BXMA 2DBUA 1TF0A 3WHSA 2QM6A 4G01A 1KW2A 3KIKA 2NQOA 2BXLA 2BXBA 2V36A 2XW1A 4J2VA 2BXQA 4Z9OA 1E7AA 4LA0A 4C31B 1VFIA 4S1YA 3W1SA 3FWBC 4F5VA 4FJCB 4IW1A 4ZUXV 1LOTA 4WA6B 1E7EA 2BXKA 3B9MA 4EMXA 5DQFA 4ZCGA 5IJEA 1E7BA 4G03A 3TDLA 1J7EA 5GINA 1JNBA 2OZBB 1GNIA 3V09A 3NVIA 3ICXA 4IW2A 4LUFA 2EFHA 1KXPD 2EFDA 3V03A 4GDLB 2I2ZA 5IJ5A 4F5TA 2LOQA 3WHRA 3LU6A 4W4UB 4DHXB 1H5WA 3JRYA 4HGMB 4OTUA 3SQJA 3VQIA 5ID9A 2DYOA 1MIWA 3FWCC 3GA9L 2XMOA 5D7GA 3NMUA 3MHSB 4JK4A 2CKXA 3M99C 1E78A 2DYMA 3H37A 4L9QA 3KJLA 4LB9A 1HK3A 4N0FD 1J78A 3NVMA 2VUFA 1E7CA 3CX9A 5DBYA 1AO6A 2EFEA 2VUEA 4K71A 3V08A 2E0YA 2Z8KA 5BPKA 2YDFA 4GDXA 1E7GA 4FK5B 4ZC6A 2AJEA 4F5UA 2VDBA 2XVWA 2BXFA 4L9KA 1MA9A 2BXPA 2XVVA 2DBXA 1NT2B 3GQXA 5IIHA 5IJFA 2JUHA 4OR0A 1UORA 1HK4A 2EFCA 1E7HA 1MIYA 2BXDA 2BXEA 3A73A 4GDKB 4ZBKA 1MIVA 4ZBQA 5GHKA 3SIVB 1BJ5A 1TXUA 2XW0A 3GQUA 2BXGA 5B5TA 1E7FA 1O9XA 4N3ZA 4ZBRA 4HGKA 1BKEA 4LUHA 5GIPA 2BXHA 4PO0A 2BXIA 5IIXA 1HK1A 2I30A 5FUOA 1FOUA 4FIPB 1H9ZA 3PLAA 4LB2A 3G9KD 1GNJA 2BXOA 2BXCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BKE A;  2BXA A;  4F5S A;  1HK5 A;  1HA2 A;  1HK2 A;  4N0U D;  3B9L A;  5IFO A;  3LU7 A;  2BXN A;  1BM0 A;  1N5U A;  2XSI A;  4OT2 A;  4L8U A;  3LU8 A;  4Z69 A;  4K2C A;  3UIV A;  5HOZ A;  5IIU A;  2XVU A;  5ID7 A;  4E99 A;  4G04 A;  2BX8 A;  1E7I A;  3JQZ A;  2BXM A;  1TF0 A;  1KW2 A;  2BXL A;  2BXB A;  2XW1 A;  4J2V A;  2BXQ A;  1E7A A;  4LA0 A;  4S1Y A;  4F5V A;  4IW1 A;  1LOT A;  1E7E A;  2BXK A;  3B9M A;  4EMX A;  5DQF A;  5IJE A;  1E7B A;  4G03 A;  3TDL A;  1J7E A;  1GNI A;  3V09 A;  4IW2 A;  4LUF A;  1KXP D;  3V03 A;  2I2Z A;  5IJ5 A;  4F5T A;  3LU6 A;  3JRY A;  4HGM B;  3SQJ A;  5ID9 A;  4JK4 A;  1E78 A;  4L9Q A;  4LB9 A;  1HK3 A;  4N0F D;  1J78 A;  2VUF A;  1E7C A;  3CX9 A;  5DBY A;  1AO6 A;  2VUE A;  3V08 A;  4K71 A;  1GNJ A;  2YDF A;  1E7G A;  4F5U A;  2VDB A;  2XVW A;  2BXF A;  4L9K A;  1MA9 A;  2BXP A;  2XVV A;  5IIH A;  5IJF A;  4OR0 A;  1UOR A;  1HK4 A;  1E7H A;  2BXD A;  3A73 A;  2BXE A;  4ZBQ A;  5GHK A;  1BJ5 A;  2XW0 A;  2BXG A;  1E7F A;  1O9X A;  4ZBR A;  4HGK A;  1BKE A;  4LUH A;  2BXH A;  4PO0 A;  2BXI A;  5IIX A;  1HK1 A;  2I30 A;  5FUO A;  1H9Z A;  4LB2 A;  2XVQ A;  2BXO A;  2BXC A; 
#chains in the Genus database with same CATH topology
 4BKE A;  2BXA A;  4BY9 C;  3SIU B;  1LNS A;  4F5S A;  2QMC A;  4NAW B;  1HK5 A;  1HA2 A;  2DG5 A;  2NNW A;  4M70 B;  1VZS A;  1HK2 A;  4N0U D;  3B9L A;  5IFO A;  3NVK A;  2DBW A;  1MUS A;  2LXS A;  3LU7 A;  2BXN A;  5GIO A;  1BM0 A;  4MBE C;  4OTT A;  1N5U A;  3MHH B;  2Z8J A;  2QHB A;  2KBZ A;  2Z8I A;  2ROH A;  2XSI A;  4OT2 A;  3FNM A;  2LQH A;  4TQ0 A;  4L8U A;  3LU8 A;  2K0N A;  4GG2 A;  4Z69 A;  4TQ1 A;  4K2C A;  3A75 A;  3UIV A;  5HOZ A;  5IIU A;  2XVU A;  5ID7 A;  3WHQ A;  1IJG A;  3H3A A;  4E99 A;  4G04 A;  2BX8 A;  1E7I A;  4DM0 A;  2E0X A;  2OT3 A;  2XVQ A;  3JQZ A;  2BXM A;  4D7X A;  2DBU A;  1TF0 A;  3WHS A;  2QM6 A;  4G01 A;  2LXT A;  1KW2 A;  3KIK A;  2NQO A;  2BXL A;  2BXB A;  2V36 A;  2XW1 A;  4J2V A;  2BXQ A;  4Z9O A;  1E7A A;  4LA0 A;  4C31 B;  1VFI A;  4S1Y A;  3W1S A;  3FWB C;  4F5V A;  1MUH A;  4FJC B;  4IW1 A;  4ZUX V;  1LOT A;  4WA6 B;  1E7E A;  2BXK A;  3B9M A;  4EMX A;  5DQF A;  4ZCG A;  5IJE A;  1E7B A;  4G03 A;  3TDL A;  1J7E A;  5GIN A;  1JNB A;  2OZB B;  1GNI A;  2AGH B;  3V09 A;  3NVI A;  3ICX A;  4IW2 A;  4LUF A;  2EFH A;  1KXP D;  2EFD A;  3V03 A;  4GDL B;  2I2Z A;  5IJ5 A;  4F5T A;  2LOQ A;  3WHR A;  3LU6 A;  4W4U B;  4DHX B;  1SB0 A;  1H5W A;  3JRY A;  4HGM B;  4OTU A;  3SQJ A;  3VQI A;  5ID9 A;  2DYO A;  1MIW A;  3FWC C;  3GA9 L;  2XMO A;  5D7G A;  3NMU A;  3MHS B;  4JK4 A;  2CKX A;  3M99 C;  1E78 A;  2DYM A;  3H37 A;  4L9Q A;  3KJL A;  4LB9 A;  1HK3 A;  4N0F D;  1J78 A;  3NVM A;  2VUF A;  1E7C A;  3CX9 A;  5DBY A;  1AO6 A;  2EFE A;  2VUE A;  4K71 A;  3V08 A;  2E0Y A;  2Z8K A;  5BPK A;  2YDF A;  4GDX A;  1E7G A;  4FK5 B;  4ZC6 A;  2AJE A;  4F5U A;  2VDB A;  2XVW A;  2BXF A;  4L9K A;  1MA9 A;  2BXP A;  2XVV A;  2DBX A;  1NT2 B;  3GQX A;  5IIH A;  5IJF A;  2JUH A;  4OR0 A;  1UOR A;  1HK4 A;  2EFC A;  1E7H A;  1MIY A;  2BXD A;  2BXE A;  3A73 A;  4GDK B;  4ZBK A;  1MIV A;  4ZBQ A;  5GHK A;  3SIV B;  1BJ5 A;  1TXU A;  1KDX A;  2XW0 A;  3GQU A;  2BXG A;  5B5T A;  1E7F A;  1O9X A;  4N3Z A;  3ECP A;  4ZBR A;  3BPJ A;  2GUT A;  4HGK A;  1BKE A;  4LUH A;  5GIP A;  2BXH A;  4PO0 A;  2BXI A;  2KWF A;  4I9O A;  5IIX A;  2LQI A;  1HK1 A;  2I30 A;  5FUO A;  1FOU A;  4FIP B;  1H9Z A;  3PLA A;  1MM8 A;  4LB2 A;  3G9K D;  1GNJ A;  2BXO A;  2BXC A; 
#chains in the Genus database with same CATH homology
 4BKE A;  2BXA A;  4BY9 C;  3SIU B;  1LNS A;  4F5S A;  2QMC A;  4NAW B;  1HK5 A;  1HA2 A;  2DG5 A;  2NNW A;  4M70 B;  1VZS A;  1HK2 A;  4N0U D;  3B9L A;  5IFO A;  3NVK A;  2DBW A;  3LU7 A;  2BXN A;  5GIO A;  1BM0 A;  4MBE C;  4OTT A;  1N5U A;  3MHH B;  2Z8J A;  2QHB A;  2KBZ A;  2Z8I A;  2ROH A;  2XSI A;  4OT2 A;  3FNM A;  4TQ0 A;  4L8U A;  3LU8 A;  4GG2 A;  4Z69 A;  4TQ1 A;  4K2C A;  3A75 A;  3UIV A;  5HOZ A;  5IIU A;  2XVU A;  5ID7 A;  3WHQ A;  1IJG A;  3H3A A;  4E99 A;  4G04 A;  2BX8 A;  1E7I A;  2E0X A;  2OT3 A;  2XVQ A;  3JQZ A;  2BXM A;  2DBU A;  1TF0 A;  3WHS A;  2QM6 A;  4G01 A;  1KW2 A;  3KIK A;  2NQO A;  2BXL A;  2BXB A;  2V36 A;  2XW1 A;  4J2V A;  2BXQ A;  4Z9O A;  1E7A A;  4LA0 A;  4C31 B;  1VFI A;  4S1Y A;  3W1S A;  3FWB C;  4F5V A;  4FJC B;  4IW1 A;  4ZUX V;  1LOT A;  4WA6 B;  1E7E A;  2BXK A;  3B9M A;  4EMX A;  5DQF A;  4ZCG A;  5IJE A;  1E7B A;  4G03 A;  3TDL A;  1J7E A;  5GIN A;  1JNB A;  2OZB B;  1GNI A;  3V09 A;  3NVI A;  3ICX A;  4IW2 A;  4LUF A;  2EFH A;  1KXP D;  2EFD A;  3V03 A;  4GDL B;  2I2Z A;  5IJ5 A;  4F5T A;  2LOQ A;  3WHR A;  3LU6 A;  4W4U B;  4DHX B;  1H5W A;  3JRY A;  4HGM B;  4OTU A;  3SQJ A;  3VQI A;  5ID9 A;  2DYO A;  1MIW A;  3FWC C;  3GA9 L;  2XMO A;  5D7G A;  3NMU A;  3MHS B;  4JK4 A;  2CKX A;  3M99 C;  1E78 A;  2DYM A;  3H37 A;  4L9Q A;  3KJL A;  4LB9 A;  1HK3 A;  4N0F D;  1J78 A;  3NVM A;  2VUF A;  1E7C A;  3CX9 A;  5DBY A;  1AO6 A;  2EFE A;  2VUE A;  4K71 A;  3V08 A;  2E0Y A;  2Z8K A;  5BPK A;  2YDF A;  4GDX A;  1E7G A;  4FK5 B;  4ZC6 A;  2AJE A;  4F5U A;  2VDB A;  2XVW A;  2BXF A;  4L9K A;  1MA9 A;  2BXP A;  2XVV A;  2DBX A;  1NT2 B;  3GQX A;  5IIH A;  5IJF A;  2JUH A;  4OR0 A;  1UOR A;  1HK4 A;  2EFC A;  1E7H A;  1MIY A;  2BXD A;  2BXE A;  3A73 A;  4GDK B;  4ZBK A;  1MIV A;  4ZBQ A;  5GHK A;  3SIV B;  1BJ5 A;  1TXU A;  2XW0 A;  3GQU A;  2BXG A;  5B5T A;  1E7F A;  1O9X A;  4N3Z A;  4ZBR A;  4HGK A;  1BKE A;  4LUH A;  5GIP A;  2BXH A;  4PO0 A;  2BXI A;  5IIX A;  1HK1 A;  2I30 A;  5FUO A;  1FOU A;  4FIP B;  1H9Z A;  3PLA A;  4LB2 A;  3G9K D;  1GNJ A;  2BXO A;  2BXC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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