3B9M | Genus

Total Genus 217

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	217
sequence length	582
structure length	582
Chain Sequence	HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Lipid binding protein
publication title	A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography pubmed doi rcsb
molecule keywords	Serum albumin
total genus	217
structure length	582
sequence length	582
ec nomenclature
pdb deposition date	2007-11-05

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3b9mA03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3b9mA02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3b9mA04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3b9mA01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3b9mA06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3b9mA05

2VUEA 2XVVA 2BXMA 4L9QA 1H9ZA 3JRYA 2BXGA 2BXAA 1E7AA 2BXKA 4LUFA 4F5SA 1O9XA 5HOZA 5IJEA 1E78A 2XW0A 4IW2A 4G03A 2BXOA 4F5VA 4L8UA 4F5TA 2XVWA 5GHKA 3V08A 1KXPD 5FUOA 5ID7A 2BXDA 2BXQA 1HK2A 2XW1A 2XVUA 1HK4A 1KW2A 1LOTA 4EMXA 4BKEA 5IIHA 4LA0A 2YDFA 2BX8A 2I30A 2BXIA 1E7IA 4N0FD 4OT2A 5IJ5A 2BXHA 1J7EA 1BJ5A 3LU6A 1AO6A 1E7HA 1HA2A 2BXEA 2BXPA 4HGMB 1E7GA 4IW1A 3A73A 1J78A 1E7EA 4N0UD 3CX9A 5DQFA 3UIVA 4LB2A 2BXLA 4OR0A 1BKEA 2VUFA 4K71A 4K2CA 1HK5A 3B9LA 5IJFA 5IIUA 1E7FA 4F5UA 4S1YA 5IFOA 4G04A 2BXBA 3JQZA 3LU7A 2XVQA 1E7BA 1GNIA 5ID9A 4LB9A 5IIXA 2XSIA 4ZBRA 4J2VA 4PO0A 1E7CA 2VDBA 3V03A 4L9KA 1TF0A 2BXCA 1HK1A 3V09A 4Z69A 2BXNA 3TDLA 3SQJA 4JK4A 3LU8A 1BM0A 4HGKA 1MA9A 2I2ZA 4LUHA 1GNJA 1N5UA 3B9MA 1HK3A 2BXFA 5DBYA 4E99A 4ZBQA 1UORA
chains in the Genus database with same CATH superfamily

2VUEA 2XVVA 1NT2B 1TXUA 3GA9L 3ICXA 5GINA 2BXMA 4L9QA 1MUHA 1VFIA 4ZUXV 1H9ZA 3JRYA 3WHRA 1MM8A 2BXGA 2V36A 2OZBB 2BXAA 3KIKA 4GDKB 3NVKA 1E7AA 1VZSA 2BXKA 2K0NA 3GQXA 4LUFA 4F5SA 1O9XA 4FK5B 3SIUB 3H37A 5HOZA 3MHSB 5IJEA 3GQUA 4ZCGA 4TQ1A 1E78A 2XW0A 2Z8KA 4G03A 4IW2A 2LOQA 2BXOA 4F5VA 4L8UA 1KDXA 4F5TA 2XVWA 5GHKA 3V08A 2Z8JA 1KXPD 4W4UB 5FUOA 4ZC6A 2BXDA 5ID7A 3FWBC 1H5WA 4FJCB 2BXQA 1LNSA 1HK2A 3KJLA 2XW1A 2XVUA 3W1SA 3NVMA 4N3ZA 1HK4A 1MIWA 1KW2A 3SIVB 1LOTA 4EMXA 2QM6A 4MBEC 1FOUA 2EFEA 3VQIA 4BKEA 5IIHA 4LA0A 2YDFA 2EFHA 3WHQA 2AGHB 2BX8A 2OT3A 2XMOA 2I30A 2BXIA 2DYMA 1E7IA 4NAWB 2DG5A 4N0FD 4OT2A 5IJ5A 2BXHA 1J7EA 1BJ5A 3LU6A 1AO6A 1E7HA 1HA2A 2BXEA 2BXPA 4HGMB 1E7GA 4IW1A 3A73A 1J78A 2EFDA 1E7EA 4N0UD 3CX9A 5DQFA 3UIVA 3PLAA 4LB2A 2BXLA 2DYOA 2GUTA 4OR0A 2AJEA 5B5TA 1BKEA 2VUFA 4K71A 4K2CA 1HK5A 3B9LA 2LQIA 5IJFA 4GG2A 2KWFA 5IIUA 1E7FA 3G9KD 4F5UA 4S1YA 5IFOA 3FNMA 2BXBA 4G04A 4TQ0A 3JQZA 3MHHB 2LXSA 2Z8IA 3LU7A 2XVQA 5GIPA 3ECPA 1E7BA 4OTTA 1GNIA 5ID9A 2LXTA 1MIVA 4LB9A 5BPKA 5IIXA 5D7GA 2XSIA 4ZBRA 4DHXB 4DM0A 2NNWA 4J2VA 2EFCA 2DBXA 1E7CA 2VDBA 4PO0A 4GDLB 4L9KA 4OTUA 3V03A 2JUHA 1TF0A 2QMCA 3A75A 2LQHA 2BXCA 2E0XA 4I9OA 2ROHA 1HK1A 4C31B 3V09A 4Z69A 3NMUA 2BXNA 3TDLA 2DBWA 3SQJA 3NVIA 4Z9OA 4JK4A 3LU8A 4ZBKA 2QHBA 2KBZA 1BM0A 1SB0A 2E0YA 4GDXA 4HGKA 2NQOA 3BPJA 1MA9A 2I2ZA 3WHSA 4LUHA 1GNJA 1N5UA 1JNBA 1MUSA 3H3AA 3B9MA 4BY9C 4WA6B 2CKXA 2DBUA 5GIOA 1HK3A 4M70B 2BXFA 4G01A 1MIYA 5DBYA 1IJGA 4E99A 4FIPB 4ZBQA 1UORA 3M99C 3FWCC 4D7XA
chains in the Genus database with same CATH topology

2VUEA 2XVVA 1NT2B 1TXUA 3GA9L 3ICXA 5GINA 2BXMA 4L9QA 1VFIA 4ZUXV 1H9ZA 3JRYA 3WHRA 2BXGA 2V36A 2OZBB 2BXAA 3KIKA 4GDKB 3NVKA 1E7AA 1VZSA 2BXKA 3GQXA 4LUFA 4F5SA 1O9XA 4FK5B 3SIUB 3H37A 5HOZA 3MHSB 5IJEA 3GQUA 4ZCGA 4TQ1A 1E78A 2XW0A 2Z8KA 4G03A 4IW2A 2LOQA 2BXOA 4F5VA 4L8UA 4F5TA 2XVWA 5GHKA 3V08A 2Z8JA 1KXPD 4W4UB 5FUOA 4ZC6A 2BXDA 5ID7A 3FWBC 1H5WA 4FJCB 2BXQA 1LNSA 1HK2A 3KJLA 2XW1A 2XVUA 3W1SA 3NVMA 4N3ZA 1HK4A 1MIWA 1KW2A 3SIVB 1LOTA 4EMXA 2QM6A 4MBEC 1FOUA 2EFEA 3VQIA 4BKEA 5IIHA 4LA0A 2YDFA 2EFHA 3WHQA 2BX8A 2OT3A 2XMOA 2I30A 2BXIA 2DYMA 1E7IA 4NAWB 2DG5A 4N0FD 4OT2A 5IJ5A 2BXHA 1J7EA 1BJ5A 3LU6A 1AO6A 1E7HA 1HA2A 2BXEA 2BXPA 4HGMB 1E7GA 4IW1A 3A73A 1J78A 2EFDA 1E7EA 4N0UD 3CX9A 5DQFA 3UIVA 3PLAA 4LB2A 2BXLA 2DYOA 4OR0A 5B5TA 2AJEA 1BKEA 2VUFA 4K71A 4K2CA 1HK5A 3B9LA 5IJFA 4GG2A 5IIUA 1E7FA 3G9KD 4F5UA 4S1YA 5IFOA 3FNMA 2BXBA 4G04A 4TQ0A 3JQZA 3MHHB 2Z8IA 3LU7A 2XVQA 5GIPA 1E7BA 4OTTA 1GNIA 5ID9A 4LB9A 1MIVA 5BPKA 5IIXA 5D7GA 2XSIA 4ZBRA 4DHXB 2NNWA 4J2VA 2EFCA 2DBXA 1E7CA 2VDBA 4PO0A 4GDLB 4L9KA 4OTUA 3V03A 2JUHA 1TF0A 2QMCA 3A75A 2BXCA 2E0XA 2ROHA 1HK1A 4C31B 3V09A 4Z69A 3NMUA 2BXNA 3TDLA 2DBWA 3SQJA 3NVIA 4Z9OA 4JK4A 3LU8A 4ZBKA 2QHBA 2KBZA 1BM0A 2E0YA 4GDXA 4HGKA 2NQOA 1MA9A 2I2ZA 3WHSA 4LUHA 1GNJA 1N5UA 1JNBA 3H3AA 3B9MA 4BY9C 4WA6B 2CKXA 2DBUA 5GIOA 1HK3A 4M70B 2BXFA 4G01A 1MIYA 5DBYA 1IJGA 4E99A 4FIPB 4ZBQA 1UORA 3M99C 3FWCC
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2VUE A;  2XVV A;  2BXM A;  4L9Q A;  1H9Z A;  3JRY A;  2BXG A;  2BXA A;  1E7A A;  2BXK A;  4LUF A;  4F5S A;  1O9X A;  5HOZ A;  5IJE A;  1E78 A;  2XW0 A;  4IW2 A;  4G03 A;  2BXO A;  4F5V A;  4L8U A;  4F5T A;  2XVW A;  5GHK A;  3V08 A;  1KXP D;  5FUO A;  5ID7 A;  2BXD A;  2BXQ A;  1HK2 A;  2XW1 A;  2XVU A;  1HK4 A;  1KW2 A;  1LOT A;  4EMX A;  4BKE A;  5IIH A;  4LA0 A;  2YDF A;  2BX8 A;  2I30 A;  2BXI A;  1E7I A;  4N0F D;  4OT2 A;  5IJ5 A;  2BXH A;  1J7E A;  1BJ5 A;  3LU6 A;  1AO6 A;  1E7H A;  1HA2 A;  2BXE A;  2BXP A;  4HGM B;  1E7G A;  4IW1 A;  3A73 A;  1J78 A;  1E7E A;  4N0U D;  3CX9 A;  5DQF A;  3UIV A;  4LB2 A;  2BXL A;  4OR0 A;  1BKE A;  2VUF A;  4K71 A;  4K2C A;  1HK5 A;  3B9L A;  5IJF A;  5IIU A;  1E7F A;  4F5U A;  4S1Y A;  5IFO A;  4G04 A;  2BXB A;  3JQZ A;  3LU7 A;  2XVQ A;  1E7B A;  1GNI A;  5ID9 A;  4LB9 A;  5IIX A;  2XSI A;  4ZBR A;  4J2V A;  4PO0 A;  1E7C A;  2VDB A;  3V03 A;  4L9K A;  1TF0 A;  2BXC A;  1HK1 A;  3V09 A;  4Z69 A;  2BXN A;  3TDL A;  3SQJ A;  4JK4 A;  3LU8 A;  1BM0 A;  4HGK A;  1MA9 A;  2I2Z A;  4LUH A;  1GNJ A;  1N5U A;  3B9M A;  1HK3 A;  2BXF A;  5DBY A;  4E99 A;  4ZBQ A;  1UOR A; 
#chains in the Genus database with same CATH topology
 2VUE A;  2XVV A;  1NT2 B;  1TXU A;  3GA9 L;  3ICX A;  5GIN A;  2BXM A;  4L9Q A;  1MUH A;  1VFI A;  4ZUX V;  1H9Z A;  3JRY A;  3WHR A;  1MM8 A;  2BXG A;  2V36 A;  2OZB B;  2BXA A;  3KIK A;  4GDK B;  3NVK A;  1E7A A;  1VZS A;  2BXK A;  2K0N A;  3GQX A;  4LUF A;  4F5S A;  1O9X A;  4FK5 B;  3SIU B;  3H37 A;  5HOZ A;  3MHS B;  5IJE A;  3GQU A;  4ZCG A;  4TQ1 A;  1E78 A;  2XW0 A;  2Z8K A;  4G03 A;  4IW2 A;  2LOQ A;  2BXO A;  4F5V A;  4L8U A;  1KDX A;  4F5T A;  2XVW A;  5GHK A;  3V08 A;  2Z8J A;  1KXP D;  4W4U B;  5FUO A;  4ZC6 A;  2BXD A;  5ID7 A;  3FWB C;  1H5W A;  4FJC B;  2BXQ A;  1LNS A;  1HK2 A;  3KJL A;  2XW1 A;  2XVU A;  3W1S A;  3NVM A;  4N3Z A;  1HK4 A;  1MIW A;  1KW2 A;  3SIV B;  1LOT A;  4EMX A;  2QM6 A;  4MBE C;  1FOU A;  2EFE A;  3VQI A;  4BKE A;  5IIH A;  4LA0 A;  2YDF A;  2EFH A;  3WHQ A;  2AGH B;  2BX8 A;  2OT3 A;  2XMO A;  2I30 A;  2BXI A;  2DYM A;  1E7I A;  4NAW B;  2DG5 A;  4N0F D;  4OT2 A;  5IJ5 A;  2BXH A;  1J7E A;  1BJ5 A;  3LU6 A;  1AO6 A;  1E7H A;  1HA2 A;  2BXE A;  2BXP A;  4HGM B;  1E7G A;  4IW1 A;  3A73 A;  1J78 A;  2EFD A;  1E7E A;  4N0U D;  3CX9 A;  5DQF A;  3UIV A;  3PLA A;  4LB2 A;  2BXL A;  2DYO A;  2GUT A;  4OR0 A;  2AJE A;  5B5T A;  1BKE A;  2VUF A;  4K71 A;  4K2C A;  1HK5 A;  3B9L A;  2LQI A;  5IJF A;  4GG2 A;  2KWF A;  5IIU A;  1E7F A;  3G9K D;  4F5U A;  4S1Y A;  5IFO A;  3FNM A;  2BXB A;  4G04 A;  4TQ0 A;  3JQZ A;  3MHH B;  2LXS A;  2Z8I A;  3LU7 A;  2XVQ A;  5GIP A;  3ECP A;  1E7B A;  4OTT A;  1GNI A;  5ID9 A;  2LXT A;  1MIV A;  4LB9 A;  5BPK A;  5IIX A;  5D7G A;  2XSI A;  4ZBR A;  4DHX B;  4DM0 A;  2NNW A;  4J2V A;  2EFC A;  2DBX A;  1E7C A;  2VDB A;  4PO0 A;  4GDL B;  4L9K A;  4OTU A;  3V03 A;  2JUH A;  1TF0 A;  2QMC A;  3A75 A;  2LQH A;  2BXC A;  2E0X A;  4I9O A;  2ROH A;  1HK1 A;  4C31 B;  3V09 A;  4Z69 A;  3NMU A;  2BXN A;  3TDL A;  2DBW A;  3SQJ A;  3NVI A;  4Z9O A;  4JK4 A;  3LU8 A;  4ZBK A;  2QHB A;  2KBZ A;  1BM0 A;  1SB0 A;  2E0Y A;  4GDX A;  4HGK A;  2NQO A;  3BPJ A;  1MA9 A;  2I2Z A;  3WHS A;  4LUH A;  1GNJ A;  1N5U A;  1JNB A;  1MUS A;  3H3A A;  3B9M A;  4BY9 C;  4WA6 B;  2CKX A;  2DBU A;  5GIO A;  1HK3 A;  4M70 B;  2BXF A;  4G01 A;  1MIY A;  5DBY A;  1IJG A;  4E99 A;  4FIP B;  4ZBQ A;  1UOR A;  3M99 C;  3FWC C;  4D7X A; 
#chains in the Genus database with same CATH homology
 2VUE A;  2XVV A;  1NT2 B;  1TXU A;  3GA9 L;  3ICX A;  5GIN A;  2BXM A;  4L9Q A;  1VFI A;  4ZUX V;  1H9Z A;  3JRY A;  3WHR A;  2BXG A;  2V36 A;  2OZB B;  2BXA A;  3KIK A;  4GDK B;  3NVK A;  1E7A A;  1VZS A;  2BXK A;  3GQX A;  4LUF A;  4F5S A;  1O9X A;  4FK5 B;  3SIU B;  3H37 A;  5HOZ A;  3MHS B;  5IJE A;  3GQU A;  4ZCG A;  4TQ1 A;  1E78 A;  2XW0 A;  2Z8K A;  4G03 A;  4IW2 A;  2LOQ A;  2BXO A;  4F5V A;  4L8U A;  4F5T A;  2XVW A;  5GHK A;  3V08 A;  2Z8J A;  1KXP D;  4W4U B;  5FUO A;  4ZC6 A;  2BXD A;  5ID7 A;  3FWB C;  1H5W A;  4FJC B;  2BXQ A;  1LNS A;  1HK2 A;  3KJL A;  2XW1 A;  2XVU A;  3W1S A;  3NVM A;  4N3Z A;  1HK4 A;  1MIW A;  1KW2 A;  3SIV B;  1LOT A;  4EMX A;  2QM6 A;  4MBE C;  1FOU A;  2EFE A;  3VQI A;  4BKE A;  5IIH A;  4LA0 A;  2YDF A;  2EFH A;  3WHQ A;  2BX8 A;  2OT3 A;  2XMO A;  2I30 A;  2BXI A;  2DYM A;  1E7I A;  4NAW B;  2DG5 A;  4N0F D;  4OT2 A;  5IJ5 A;  2BXH A;  1J7E A;  1BJ5 A;  3LU6 A;  1AO6 A;  1E7H A;  1HA2 A;  2BXE A;  2BXP A;  4HGM B;  1E7G A;  4IW1 A;  3A73 A;  1J78 A;  2EFD A;  1E7E A;  4N0U D;  3CX9 A;  5DQF A;  3UIV A;  3PLA A;  4LB2 A;  2BXL A;  2DYO A;  4OR0 A;  5B5T A;  2AJE A;  1BKE A;  2VUF A;  4K71 A;  4K2C A;  1HK5 A;  3B9L A;  5IJF A;  4GG2 A;  5IIU A;  1E7F A;  3G9K D;  4F5U A;  4S1Y A;  5IFO A;  3FNM A;  2BXB A;  4G04 A;  4TQ0 A;  3JQZ A;  3MHH B;  2Z8I A;  3LU7 A;  2XVQ A;  5GIP A;  1E7B A;  4OTT A;  1GNI A;  5ID9 A;  4LB9 A;  1MIV A;  5BPK A;  5IIX A;  5D7G A;  2XSI A;  4ZBR A;  4DHX B;  2NNW A;  4J2V A;  2EFC A;  2DBX A;  1E7C A;  2VDB A;  4PO0 A;  4GDL B;  4L9K A;  4OTU A;  3V03 A;  2JUH A;  1TF0 A;  2QMC A;  3A75 A;  2BXC A;  2E0X A;  2ROH A;  1HK1 A;  4C31 B;  3V09 A;  4Z69 A;  3NMU A;  2BXN A;  3TDL A;  2DBW A;  3SQJ A;  3NVI A;  4Z9O A;  4JK4 A;  3LU8 A;  4ZBK A;  2QHB A;  2KBZ A;  1BM0 A;  2E0Y A;  4GDX A;  4HGK A;  2NQO A;  1MA9 A;  2I2Z A;  3WHS A;  4LUH A;  1GNJ A;  1N5U A;  1JNB A;  3H3A A;  3B9M A;  4BY9 C;  4WA6 B;  2CKX A;  2DBU A;  5GIO A;  1HK3 A;  4M70 B;  2BXF A;  4G01 A;  1MIY A;  5DBY A;  1IJG A;  4E99 A;  4FIP B;  4ZBQ A;  1UOR A;  3M99 C;  3FWC C;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3B9MA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations