3LU7A

Human serum albumin in complex with compound 2
Total Genus 208
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
208
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Serum albumin
total genus 208
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3lu7A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3lu7A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3lu7A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3lu7A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3lu7A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3lu7A05
1GNJA 1GNIA 4PO0A 4IW1A 5ID7A 3SQJA 2XVUA 1LOTA 4L9QA 1J7EA 1KW2A 4S1YA 2XVQA 1HK3A 2BXLA 4F5TA 4K2CA 5IJFA 1E7GA 2XSIA 4HGMB 2BX8A 1AO6A 3LU8A 2XW1A 2VUFA 4L9KA 5IFOA 1N5UA 2XVWA 3LU6A 4F5UA 2VUEA 4Z69A 3JRYA 4G04A 4E99A 1E7CA 2I2ZA 3V03A 4LA0A 4LUFA 5IIHA 1HK5A 1MA9A 4HGKA 4ZBQA 1HK2A 4OR0A 2BXKA 2BXQA 4IW2A 1E7BA 4N0FD 1E7FA 3A73A 2BXDA 4LUHA 5IIXA 4G03A 2I30A 1E7HA 3LU7A 2BXPA 1BJ5A 1HA2A 2BXFA 1BKEA 2BXIA 2XVVA 4BKEA 1J78A 1HK4A 2BXNA 2BXHA 2BXAA 4LB2A 4F5VA 2BXEA 2BXOA 2YDFA 5DQFA 1O9XA 2BXCA 1E78A 5DBYA 5FUOA 1TF0A 2VDBA 4L8UA 1H9ZA 2BXBA 4ZBRA 1HK1A 3UIVA 3V09A 4J2VA 4F5SA 2BXMA 5IJ5A 1KXPD 4EMXA 3CX9A 4N0UD 3JQZA 3TDLA 4OT2A 5ID9A 2BXGA 4LB9A 5HOZA 3B9MA 4K71A 4JK4A 3V08A 5IJEA 2XW0A 5GHKA 1E7AA 5IIUA 1E7IA 1UORA 1BM0A 3B9LA 1E7EA
chains in the Genus database with same CATH superfamily
1GNJA 1GNIA 3MHHB 3ICXA 1NT2B 4PO0A 4TQ0A 4IW1A 5ID7A 3SQJA 4Z9OA 2XVUA 2NNWA 3NVIA 1LOTA 4L9QA 1J7EA 1KW2A 4C31B 4S1YA 2DBUA 2DYMA 2XVQA 4M70B 2KBZA 1HK3A 1KDXA 4FIPB 2E0YA 1TXUA 2BXLA 1H5WA 2QMCA 4OTTA 4I9OA 4F5TA 4GG2A 2AGHB 4K2CA 2LQHA 2OT3A 3PLAA 3G9KD 2QHBA 4BY9C 5IJFA 1E7GA 2XSIA 2KWFA 2BX8A 4HGMB 4ZCGA 1AO6A 3LU8A 2XW1A 2VUFA 4L9KA 4WA6B 5IFOA 1JNBA 2EFCA 1N5UA 2XVWA 2EFEA 3LU6A 1SB0A 4DHXB 2JUHA 4F5UA 2VUEA 4Z69A 3JRYA 4G04A 4E99A 3A75A 1E7CA 2I2ZA 2Z8JA 3H3AA 3V03A 4GDXA 4N3ZA 2Z8IA 1MIWA 4LA0A 4GDLB 4LUFA 2DBXA 1HK5A 1MA9A 2CKXA 4HGKA 4ZBQA 5IIHA 3NVKA 1HK2A 3SIVB 4OR0A 4MBEC 1FOUA 2BXKA 2DG5A 2BXQA 4IW2A 1E7BA 3FNMA 2EFDA 4N0FD 1E7FA 3W1SA 3A73A 3WHRA 3WHSA 2BXDA 4LUHA 2AJEA 4G03A 5IIXA 2I30A 2LXSA 5GIPA 1E7HA 3LU7A 3H37A 2XMOA 1VZSA 2LXTA 2BXPA 1BJ5A 2NQOA 4BKEA 1HA2A 2BXFA 4GDKB 5GIOA 2OZBB 1BKEA 2BXIA 3NVMA 2XVVA 4ZBKA 1J78A 1HK4A 2BXNA 2BXHA 2BXAA 3GQUA 4LB2A 3WHQA 2BXEA 4F5VA 1VFIA 3KIKA 2BXOA 3FWBC 2YDFA 3GQXA 2LQIA 3GA9L 1LNSA 3MHSB 4TQ1A 5D7GA 5BPKA 2ROHA 3BPJA 5DQFA 1O9XA 2BXCA 2EFHA 1E78A 5B5TA 2GUTA 5DBYA 5FUOA 4FJCB 2K0NA 1TF0A 2VDBA 2QM6A 4L8UA 1MUSA 4W4UB 2LOQA 1H9ZA 2BXBA 4ZBRA 1HK1A 3UIVA 3V09A 4FK5B 4J2VA 2BXMA 5IJ5A 4F5SA 1KXPD 4EMXA 3CX9A 4N0UD 3JQZA 3FWCC 3TDLA 4OT2A 5ID9A 3M99C 1MUHA 3NMUA 4OTUA 2BXGA 2DBWA 4LB9A 5HOZA 2E0XA 3B9MA 4K71A 4JK4A 3V08A 3VQIA 4G01A 5IJEA 3SIUB 2XW0A 2Z8KA 5GHKA 3KJLA 3ECPA 1E7AA 4DM0A 1IJGA 4ZC6A 4ZUXV 5IIUA 1E7IA 1UORA 1MIYA 5GINA 1BM0A 4D7XA 1MM8A 2DYOA 1MIVA 3B9LA 1E7EA 4NAWB 2V36A
chains in the Genus database with same CATH topology
1GNJA 1GNIA 3MHHB 3ICXA 1NT2B 4PO0A 4TQ0A 4IW1A 5ID7A 3SQJA 4Z9OA 2XVUA 2NNWA 3NVIA 1LOTA 4L9QA 1J7EA 1KW2A 4C31B 4S1YA 2DBUA 2DYMA 2XVQA 4M70B 2KBZA 1HK3A 4FIPB 2E0YA 1TXUA 2BXLA 1H5WA 2QMCA 4OTTA 4F5TA 4GG2A 4K2CA 2OT3A 3PLAA 3G9KD 2QHBA 4BY9C 5IJFA 1E7GA 2XSIA 4HGMB 2BX8A 4ZCGA 1AO6A 3LU8A 2XW1A 2VUFA 4L9KA 4WA6B 5IFOA 1JNBA 2EFCA 1N5UA 2XVWA 2EFEA 3LU6A 4F5UA 4DHXB 2JUHA 2VUEA 4Z69A 3JRYA 4G04A 4E99A 3A75A 1E7CA 2I2ZA 2Z8JA 3H3AA 3V03A 4GDXA 4N3ZA 2Z8IA 1MIWA 4LA0A 4GDLB 4LUFA 2DBXA 1HK5A 1MA9A 2CKXA 4HGKA 4ZBQA 5IIHA 3NVKA 1HK2A 3SIVB 4OR0A 4MBEC 1FOUA 2BXKA 2DG5A 2BXQA 4IW2A 1E7BA 3FNMA 2EFDA 4N0FD 1E7FA 3W1SA 3A73A 3WHRA 3WHSA 2BXDA 4LUHA 2AJEA 4G03A 5IIXA 2I30A 5GIPA 1E7HA 3LU7A 3H37A 2XMOA 1VZSA 4BKEA 2BXPA 1BJ5A 2NQOA 1HA2A 2BXFA 4GDKB 5GIOA 2OZBB 1BKEA 2BXIA 3NVMA 2XVVA 4ZBKA 1J78A 1HK4A 2BXNA 2BXHA 2BXAA 3GQUA 4LB2A 3WHQA 2BXEA 4F5VA 1VFIA 3KIKA 2BXOA 3FWBC 2YDFA 3GQXA 3GA9L 3MHSB 1LNSA 4TQ1A 5D7GA 5BPKA 2ROHA 5DQFA 1O9XA 2BXCA 2EFHA 1E78A 5B5TA 5DBYA 5FUOA 4FJCB 1TF0A 2VDBA 2QM6A 4L8UA 4W4UB 2LOQA 1H9ZA 2BXBA 4ZBRA 1HK1A 3UIVA 3V09A 4FK5B 4J2VA 2BXMA 5IJ5A 4F5SA 1KXPD 4EMXA 3CX9A 4N0UD 3JQZA 3FWCC 3TDLA 4OT2A 5ID9A 3M99C 3NMUA 4OTUA 2BXGA 2DBWA 4LB9A 5HOZA 2E0XA 3B9MA 4K71A 4JK4A 3V08A 3VQIA 4G01A 5IJEA 3SIUB 2XW0A 2Z8KA 5GHKA 3KJLA 1E7AA 1IJGA 4ZC6A 4ZUXV 5IIUA 1E7IA 1UORA 1MIYA 5GINA 1BM0A 2DYOA 1MIVA 3B9LA 1E7EA 4NAWB 2V36A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GNJ A;  1GNI A;  4PO0 A;  4IW1 A;  5ID7 A;  3SQJ A;  2XVU A;  1LOT A;  4L9Q A;  1J7E A;  1KW2 A;  4S1Y A;  2XVQ A;  1HK3 A;  2BXL A;  4F5T A;  4K2C A;  5IJF A;  1E7G A;  2XSI A;  4HGM B;  2BX8 A;  1AO6 A;  3LU8 A;  2XW1 A;  2VUF A;  4L9K A;  5IFO A;  1N5U A;  2XVW A;  3LU6 A;  4F5U A;  2VUE A;  4Z69 A;  3JRY A;  4G04 A;  4E99 A;  1E7C A;  2I2Z A;  3V03 A;  4LA0 A;  4LUF A;  5IIH A;  1HK5 A;  1MA9 A;  4HGK A;  4ZBQ A;  1HK2 A;  4OR0 A;  2BXK A;  2BXQ A;  4IW2 A;  1E7B A;  4N0F D;  1E7F A;  3A73 A;  2BXD A;  4LUH A;  5IIX A;  4G03 A;  2I30 A;  1E7H A;  3LU7 A;  2BXP A;  1BJ5 A;  1HA2 A;  2BXF A;  1BKE A;  2BXI A;  2XVV A;  4BKE A;  1J78 A;  1HK4 A;  2BXN A;  2BXH A;  2BXA A;  4LB2 A;  4F5V A;  2BXE A;  2BXO A;  2YDF A;  5DQF A;  1O9X A;  2BXC A;  1E78 A;  5DBY A;  5FUO A;  1TF0 A;  2VDB A;  4L8U A;  1H9Z A;  2BXB A;  4ZBR A;  1HK1 A;  3UIV A;  3V09 A;  4J2V A;  4F5S A;  2BXM A;  5IJ5 A;  1KXP D;  4EMX A;  3CX9 A;  4N0U D;  3JQZ A;  3TDL A;  4OT2 A;  5ID9 A;  2BXG A;  4LB9 A;  5HOZ A;  3B9M A;  4K71 A;  4JK4 A;  3V08 A;  5IJE A;  2XW0 A;  5GHK A;  1E7A A;  5IIU A;  1E7I A;  1UOR A;  1BM0 A;  3B9L A;  1E7E A; 
#chains in the Genus database with same CATH topology
 1GNJ A;  1GNI A;  3MHH B;  3ICX A;  1NT2 B;  4PO0 A;  4TQ0 A;  4IW1 A;  5ID7 A;  3SQJ A;  4Z9O A;  2XVU A;  2NNW A;  3NVI A;  1LOT A;  4L9Q A;  1J7E A;  1KW2 A;  4C31 B;  4S1Y A;  2DBU A;  2DYM A;  2XVQ A;  4M70 B;  2KBZ A;  1HK3 A;  1KDX A;  4FIP B;  2E0Y A;  1TXU A;  2BXL A;  1H5W A;  2QMC A;  4OTT A;  4I9O A;  4F5T A;  4GG2 A;  2AGH B;  4K2C A;  2LQH A;  2OT3 A;  3PLA A;  3G9K D;  2QHB A;  4BY9 C;  5IJF A;  1E7G A;  2XSI A;  2KWF A;  2BX8 A;  4HGM B;  4ZCG A;  1AO6 A;  3LU8 A;  2XW1 A;  2VUF A;  4L9K A;  4WA6 B;  5IFO A;  1JNB A;  2EFC A;  1N5U A;  2XVW A;  2EFE A;  3LU6 A;  1SB0 A;  4DHX B;  2JUH A;  4F5U A;  2VUE A;  4Z69 A;  3JRY A;  4G04 A;  4E99 A;  3A75 A;  1E7C A;  2I2Z A;  2Z8J A;  3H3A A;  3V03 A;  4GDX A;  4N3Z A;  2Z8I A;  1MIW A;  4LA0 A;  4GDL B;  4LUF A;  2DBX A;  1HK5 A;  1MA9 A;  2CKX A;  4HGK A;  4ZBQ A;  5IIH A;  3NVK A;  1HK2 A;  3SIV B;  4OR0 A;  4MBE C;  1FOU A;  2BXK A;  2DG5 A;  2BXQ A;  4IW2 A;  1E7B A;  3FNM A;  2EFD A;  4N0F D;  1E7F A;  3W1S A;  3A73 A;  3WHR A;  3WHS A;  2BXD A;  4LUH A;  2AJE A;  4G03 A;  5IIX A;  2I30 A;  2LXS A;  5GIP A;  1E7H A;  3LU7 A;  3H37 A;  2XMO A;  1VZS A;  2LXT A;  2BXP A;  1BJ5 A;  2NQO A;  4BKE A;  1HA2 A;  2BXF A;  4GDK B;  5GIO A;  2OZB B;  1BKE A;  2BXI A;  3NVM A;  2XVV A;  4ZBK A;  1J78 A;  1HK4 A;  2BXN A;  2BXH A;  2BXA A;  3GQU A;  4LB2 A;  3WHQ A;  2BXE A;  4F5V A;  1VFI A;  3KIK A;  2BXO A;  3FWB C;  2YDF A;  3GQX A;  2LQI A;  3GA9 L;  1LNS A;  3MHS B;  4TQ1 A;  5D7G A;  5BPK A;  2ROH A;  3BPJ A;  5DQF A;  1O9X A;  2BXC A;  2EFH A;  1E78 A;  5B5T A;  2GUT A;  5DBY A;  5FUO A;  4FJC B;  2K0N A;  1TF0 A;  2VDB A;  2QM6 A;  4L8U A;  1MUS A;  4W4U B;  2LOQ A;  1H9Z A;  2BXB A;  4ZBR A;  1HK1 A;  3UIV A;  3V09 A;  4FK5 B;  4J2V A;  2BXM A;  5IJ5 A;  4F5S A;  1KXP D;  4EMX A;  3CX9 A;  4N0U D;  3JQZ A;  3FWC C;  3TDL A;  4OT2 A;  5ID9 A;  3M99 C;  1MUH A;  3NMU A;  4OTU A;  2BXG A;  2DBW A;  4LB9 A;  5HOZ A;  2E0X A;  3B9M A;  4K71 A;  4JK4 A;  3V08 A;  3VQI A;  4G01 A;  5IJE A;  3SIU B;  2XW0 A;  2Z8K A;  5GHK A;  3KJL A;  3ECP A;  1E7A A;  4DM0 A;  1IJG A;  4ZC6 A;  4ZUX V;  5IIU A;  1E7I A;  1UOR A;  1MIY A;  5GIN A;  1BM0 A;  4D7X A;  1MM8 A;  2DYO A;  1MIV A;  3B9L A;  1E7E A;  4NAW B;  2V36 A; 
#chains in the Genus database with same CATH homology
 1GNJ A;  1GNI A;  3MHH B;  3ICX A;  1NT2 B;  4PO0 A;  4TQ0 A;  4IW1 A;  5ID7 A;  3SQJ A;  4Z9O A;  2XVU A;  2NNW A;  3NVI A;  1LOT A;  4L9Q A;  1J7E A;  1KW2 A;  4C31 B;  4S1Y A;  2DBU A;  2DYM A;  2XVQ A;  4M70 B;  2KBZ A;  1HK3 A;  4FIP B;  2E0Y A;  1TXU A;  2BXL A;  1H5W A;  2QMC A;  4OTT A;  4F5T A;  4GG2 A;  4K2C A;  2OT3 A;  3PLA A;  3G9K D;  2QHB A;  4BY9 C;  5IJF A;  1E7G A;  2XSI A;  4HGM B;  2BX8 A;  4ZCG A;  1AO6 A;  3LU8 A;  2XW1 A;  2VUF A;  4L9K A;  4WA6 B;  5IFO A;  1JNB A;  2EFC A;  1N5U A;  2XVW A;  2EFE A;  3LU6 A;  4F5U A;  4DHX B;  2JUH A;  2VUE A;  4Z69 A;  3JRY A;  4G04 A;  4E99 A;  3A75 A;  1E7C A;  2I2Z A;  2Z8J A;  3H3A A;  3V03 A;  4GDX A;  4N3Z A;  2Z8I A;  1MIW A;  4LA0 A;  4GDL B;  4LUF A;  2DBX A;  1HK5 A;  1MA9 A;  2CKX A;  4HGK A;  4ZBQ A;  5IIH A;  3NVK A;  1HK2 A;  3SIV B;  4OR0 A;  4MBE C;  1FOU A;  2BXK A;  2DG5 A;  2BXQ A;  4IW2 A;  1E7B A;  3FNM A;  2EFD A;  4N0F D;  1E7F A;  3W1S A;  3A73 A;  3WHR A;  3WHS A;  2BXD A;  4LUH A;  2AJE A;  4G03 A;  5IIX A;  2I30 A;  5GIP A;  1E7H A;  3LU7 A;  3H37 A;  2XMO A;  1VZS A;  4BKE A;  2BXP A;  1BJ5 A;  2NQO A;  1HA2 A;  2BXF A;  4GDK B;  5GIO A;  2OZB B;  1BKE A;  2BXI A;  3NVM A;  2XVV A;  4ZBK A;  1J78 A;  1HK4 A;  2BXN A;  2BXH A;  2BXA A;  3GQU A;  4LB2 A;  3WHQ A;  2BXE A;  4F5V A;  1VFI A;  3KIK A;  2BXO A;  3FWB C;  2YDF A;  3GQX A;  3GA9 L;  3MHS B;  1LNS A;  4TQ1 A;  5D7G A;  5BPK A;  2ROH A;  5DQF A;  1O9X A;  2BXC A;  2EFH A;  1E78 A;  5B5T A;  5DBY A;  5FUO A;  4FJC B;  1TF0 A;  2VDB A;  2QM6 A;  4L8U A;  4W4U B;  2LOQ A;  1H9Z A;  2BXB A;  4ZBR A;  1HK1 A;  3UIV A;  3V09 A;  4FK5 B;  4J2V A;  2BXM A;  5IJ5 A;  4F5S A;  1KXP D;  4EMX A;  3CX9 A;  4N0U D;  3JQZ A;  3FWC C;  3TDL A;  4OT2 A;  5ID9 A;  3M99 C;  3NMU A;  4OTU A;  2BXG A;  2DBW A;  4LB9 A;  5HOZ A;  2E0X A;  3B9M A;  4K71 A;  4JK4 A;  3V08 A;  3VQI A;  4G01 A;  5IJE A;  3SIU B;  2XW0 A;  2Z8K A;  5GHK A;  3KJL A;  1E7A A;  1IJG A;  4ZC6 A;  4ZUX V;  5IIU A;  1E7I A;  1UOR A;  1MIY A;  5GIN A;  1BM0 A;  2DYO A;  1MIV A;  3B9L A;  1E7E A;  4NAW B;  2V36 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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