3TDLA

Structure of human serum albumin in complex with dauda
Total Genus 217
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
217
sequence length
582
structure length
578
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Serum albumin
total genus 217
structure length 578
sequence length 582
ec nomenclature
pdb deposition date 2011-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3tdlA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3tdlA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3tdlA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3tdlA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3tdlA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3tdlA05
2BXFA 3A73A 2BXNA 1HK5A 2BXHA 4LB2A 1E7AA 2BXPA 1LOTA 1E7GA 1HK2A 2XVQA 4S1YA 3LU7A 1KW2A 1O9XA 4IW2A 4J2VA 2BXAA 3TDLA 4HGKA 4ZBRA 2BXCA 2I2ZA 3B9LA 1E78A 3SQJA 4F5VA 1HK4A 1J7EA 2BXIA 2VUFA 2XVWA 1GNJA 1HK1A 4OR0A 2BXOA 4JK4A 1N5UA 4LUFA 2I30A 4LUHA 1J78A 4PO0A 1BJ5A 1E7IA 3LU6A 5IJFA 3V09A 2BXEA 5IIHA 1H9ZA 5GHKA 1E7EA 5IJ5A 2BXMA 2BXKA 2BXDA 1UORA 2XVVA 1AO6A 2XVUA 2XW1A 1E7FA 2BXBA 3B9MA 3JRYA 4E99A 2YDFA 5IIUA 5DQFA 1BM0A 2VDBA 2BXGA 1MA9A 3LU8A 4K71A 4L9QA 5IIXA 2BXLA 2XSIA 1KXPD 1E7CA 4L9KA 2XW0A 4OT2A 4EMXA 1HK3A 4G04A 4IW1A 3V03A 4N0FD 4ZBQA 4L8UA 4Z69A 5HOZA 1GNIA 4F5UA 4LB9A 2BXQA 5IFOA 5ID7A 4BKEA 1HA2A 5FUOA 2VUEA 4LA0A 3CX9A 1TF0A 4N0UD 4G03A 3UIVA 5DBYA 5ID9A 4HGMB 1E7BA 5IJEA 4F5TA 3V08A 4F5SA 1E7HA 4K2CA 1BKEA 3JQZA 2BX8A
chains in the Genus database with same CATH superfamily
2BXFA 3A73A 2BXNA 1HK5A 2BXHA 4LB2A 1E7AA 2BXPA 2LXSA 1LOTA 1E7GA 3ICXA 3JQZA 2LQHA 1HK2A 2XVQA 2NQOA 4OTUA 3LU7A 4S1YA 3MHHB 3G9KD 1KW2A 1O9XA 4IW2A 4J2VA 2V36A 2BXAA 4ZBKA 3TDLA 1KDXA 2QHBA 4HGKA 4GDLB 4ZBRA 2BXCA 2E0XA 2I2ZA 3B9LA 4W4UB 1E78A 3SQJA 4F5VA 1HK4A 1J7EA 1TXUA 2BXIA 2DYOA 2VUFA 2XVWA 4GDKB 5GIPA 1GNJA 1FOUA 3BPJA 1HK1A 2CKXA 4OR0A 2BXOA 4ZUXV 3NVIA 3GQXA 4JK4A 4DM0A 1N5UA 4OTTA 4LUFA 2I30A 4LUHA 1J78A 4PO0A 1BJ5A 1E7IA 2KBZA 3LU6A 1LNSA 2DBXA 5IJFA 4MBEC 2DBUA 3V09A 5GIOA 1IJGA 2BXEA 2AJEA 4GDXA 3H37A 5IIHA 3KIKA 2LOQA 1H9ZA 2OT3A 5GHKA 1VZSA 1E7EA 5IJ5A 2BXMA 2BXKA 2BXDA 2KWFA 4TQ1A 2EFDA 4BY9C 1UORA 2XVVA 2ROHA 4D7XA 1AO6A 1H5WA 2XVUA 2XW1A 2JUHA 1E7FA 2BXBA 3B9MA 5B5TA 4M70B 2Z8JA 3JRYA 3FWCC 4E99A 1MIVA 2XMOA 5IIUA 5DQFA 1BM0A 2VDBA 2BXGA 3KJLA 1MA9A 3LU8A 3W1SA 3FWBC 4K71A 4L9QA 4WA6B 1MUHA 3NVKA 5IIXA 2BXLA 2XSIA 1KXPD 2Z8KA 2QMCA 4ZC6A 5GINA 2E0YA 1E7CA 2EFHA 1MM8A 2EFCA 3ECPA 4TQ0A 4L9KA 2XW0A 2AGHB 2DG5A 4OT2A 3M99C 4EMXA 1HK3A 4G04A 3WHRA 3SIUB 2DBWA 4IW1A 3WHSA 3V03A 4N0FD 3NMUA 1NT2B 4L8UA 4ZBQA 4Z69A 5HOZA 4FIPB 1GNIA 3SIVB 2QM6A 3GA9L 4ZCGA 5BPKA 1MIWA 4F5UA 4I9OA 4LB9A 2BXQA 4FK5B 3VQIA 5IFOA 2K0NA 4G01A 3MHSB 5ID7A 4Z9OA 4BKEA 1HA2A 4DHXB 5FUOA 2VUEA 4LA0A 3CX9A 2GUTA 1TF0A 2NNWA 2DYMA 4C31B 4N0UD 4G03A 4NAWB 4K2CA 3UIVA 3WHQA 5DBYA 5ID9A 3GQUA 3H3AA 1MUSA 5D7GA 4HGMB 3FNMA 1E7BA 4GG2A 2Z8IA 1JNBA 2LQIA 5IJEA 3PLAA 4FJCB 2LXTA 3NVMA 4F5TA 1SB0A 2OZBB 3V08A 1VFIA 4N3ZA 4F5SA 1E7HA 2EFEA 3A75A 1MIYA 1BKEA 2YDFA 2BX8A
chains in the Genus database with same CATH topology
2BXFA 3A73A 2BXNA 1HK5A 2BXHA 4LB2A 1E7AA 2BXPA 1LOTA 1E7GA 3ICXA 3JQZA 1HK2A 2XVQA 2NQOA 4OTUA 3LU7A 4S1YA 3MHHB 3G9KD 1KW2A 1O9XA 4IW2A 4J2VA 2V36A 2BXAA 4ZBKA 3TDLA 2QHBA 4HGKA 4GDLB 4ZBRA 2BXCA 2E0XA 2I2ZA 3B9LA 4W4UB 1E78A 3SQJA 4F5VA 1HK4A 1J7EA 1TXUA 2BXIA 2DYOA 2VUFA 2XVWA 4GDKB 5GIPA 1GNJA 1FOUA 1HK1A 2CKXA 4OR0A 2BXOA 4ZUXV 3NVIA 3GQXA 4JK4A 1N5UA 4OTTA 4LUFA 2I30A 4LUHA 1J78A 4PO0A 1BJ5A 1E7IA 2KBZA 3LU6A 1LNSA 2DBXA 5IJFA 4MBEC 2DBUA 3V09A 5GIOA 1IJGA 2BXEA 2AJEA 4GDXA 3H37A 5IIHA 3KIKA 2LOQA 1H9ZA 2OT3A 5GHKA 1VZSA 1E7EA 5IJ5A 2BXMA 2BXKA 2BXDA 4TQ1A 2EFDA 4BY9C 1UORA 2XVVA 2ROHA 1AO6A 1H5WA 2XVUA 2XW1A 2JUHA 1E7FA 2BXBA 3B9MA 5B5TA 4M70B 2Z8JA 3JRYA 3FWCC 4E99A 1MIVA 2XMOA 5IIUA 5DQFA 1BM0A 2VDBA 2BXGA 3KJLA 1MA9A 3LU8A 3W1SA 3FWBC 4K71A 4L9QA 4WA6B 3NVKA 5IIXA 2BXLA 2XSIA 1KXPD 2Z8KA 2QMCA 4ZC6A 5GINA 2E0YA 1E7CA 2EFHA 2EFCA 4TQ0A 4L9KA 2XW0A 2DG5A 4OT2A 3M99C 4EMXA 1HK3A 4G04A 3WHRA 3SIUB 2DBWA 4IW1A 3WHSA 3V03A 4N0FD 3NMUA 1NT2B 4L8UA 4ZBQA 4Z69A 5HOZA 4FIPB 1GNIA 3SIVB 2QM6A 3GA9L 4ZCGA 5BPKA 1MIWA 4F5UA 4LB9A 2BXQA 4FK5B 3VQIA 5IFOA 4G01A 3MHSB 5ID7A 4Z9OA 4BKEA 1HA2A 4DHXB 5FUOA 2VUEA 4LA0A 3CX9A 1TF0A 2NNWA 2DYMA 4C31B 4N0UD 4G03A 4NAWB 4K2CA 3UIVA 3WHQA 5DBYA 5ID9A 3GQUA 3H3AA 5D7GA 4HGMB 3FNMA 1E7BA 4GG2A 2Z8IA 1JNBA 5IJEA 3PLAA 4FJCB 3NVMA 4F5TA 2OZBB 3V08A 1VFIA 4N3ZA 4F5SA 1E7HA 2EFEA 3A75A 1MIYA 1BKEA 2YDFA 2BX8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXF A;  3A73 A;  2BXN A;  1HK5 A;  2BXH A;  4LB2 A;  1E7A A;  2BXP A;  1LOT A;  1E7G A;  1HK2 A;  2XVQ A;  4S1Y A;  3LU7 A;  1KW2 A;  1O9X A;  4IW2 A;  4J2V A;  2BXA A;  3TDL A;  4HGK A;  4ZBR A;  2BXC A;  2I2Z A;  3B9L A;  1E78 A;  3SQJ A;  4F5V A;  1HK4 A;  1J7E A;  2BXI A;  2VUF A;  2XVW A;  1GNJ A;  1HK1 A;  4OR0 A;  2BXO A;  4JK4 A;  1N5U A;  4LUF A;  2I30 A;  4LUH A;  1J78 A;  4PO0 A;  1BJ5 A;  1E7I A;  3LU6 A;  5IJF A;  3V09 A;  2BXE A;  5IIH A;  1H9Z A;  5GHK A;  1E7E A;  5IJ5 A;  2BXM A;  2BXK A;  2BXD A;  1UOR A;  2XVV A;  1AO6 A;  2XVU A;  2XW1 A;  1E7F A;  2BXB A;  3B9M A;  3JRY A;  4E99 A;  2YDF A;  5IIU A;  5DQF A;  1BM0 A;  2VDB A;  2BXG A;  1MA9 A;  3LU8 A;  4K71 A;  4L9Q A;  5IIX A;  2BXL A;  2XSI A;  1KXP D;  1E7C A;  4L9K A;  2XW0 A;  4OT2 A;  4EMX A;  1HK3 A;  4G04 A;  4IW1 A;  3V03 A;  4N0F D;  4ZBQ A;  4L8U A;  4Z69 A;  5HOZ A;  1GNI A;  4F5U A;  4LB9 A;  2BXQ A;  5IFO A;  5ID7 A;  4BKE A;  1HA2 A;  5FUO A;  2VUE A;  4LA0 A;  3CX9 A;  1TF0 A;  4N0U D;  4G03 A;  3UIV A;  5DBY A;  5ID9 A;  4HGM B;  1E7B A;  5IJE A;  4F5T A;  3V08 A;  4F5S A;  1E7H A;  4K2C A;  1BKE A;  3JQZ A;  2BX8 A; 
#chains in the Genus database with same CATH topology
 2BXF A;  3A73 A;  2BXN A;  1HK5 A;  2BXH A;  4LB2 A;  1E7A A;  2BXP A;  2LXS A;  1LOT A;  1E7G A;  3ICX A;  3JQZ A;  2LQH A;  1HK2 A;  2XVQ A;  2NQO A;  4OTU A;  3LU7 A;  4S1Y A;  3MHH B;  3G9K D;  1KW2 A;  1O9X A;  4IW2 A;  4J2V A;  2V36 A;  2BXA A;  4ZBK A;  3TDL A;  1KDX A;  2QHB A;  4HGK A;  4GDL B;  4ZBR A;  2BXC A;  2E0X A;  2I2Z A;  3B9L A;  4W4U B;  1E78 A;  3SQJ A;  4F5V A;  1HK4 A;  1J7E A;  1TXU A;  2BXI A;  2DYO A;  2VUF A;  2XVW A;  4GDK B;  5GIP A;  1GNJ A;  1FOU A;  3BPJ A;  1HK1 A;  2CKX A;  4OR0 A;  2BXO A;  4ZUX V;  3NVI A;  3GQX A;  4JK4 A;  4DM0 A;  1N5U A;  4OTT A;  4LUF A;  2I30 A;  4LUH A;  1J78 A;  4PO0 A;  1BJ5 A;  1E7I A;  2KBZ A;  3LU6 A;  1LNS A;  2DBX A;  5IJF A;  4MBE C;  2DBU A;  3V09 A;  5GIO A;  1IJG A;  2BXE A;  2AJE A;  4GDX A;  3H37 A;  5IIH A;  3KIK A;  2LOQ A;  1H9Z A;  2OT3 A;  5GHK A;  1VZS A;  1E7E A;  5IJ5 A;  2BXM A;  2BXK A;  2BXD A;  2KWF A;  4TQ1 A;  2EFD A;  4BY9 C;  1UOR A;  2XVV A;  2ROH A;  4D7X A;  1AO6 A;  1H5W A;  2XVU A;  2XW1 A;  2JUH A;  1E7F A;  2BXB A;  3B9M A;  5B5T A;  4M70 B;  2Z8J A;  3JRY A;  3FWC C;  4E99 A;  1MIV A;  2XMO A;  5IIU A;  5DQF A;  1BM0 A;  2VDB A;  2BXG A;  3KJL A;  1MA9 A;  3LU8 A;  3W1S A;  3FWB C;  4K71 A;  4L9Q A;  4WA6 B;  1MUH A;  3NVK A;  5IIX A;  2BXL A;  2XSI A;  1KXP D;  2Z8K A;  2QMC A;  4ZC6 A;  5GIN A;  2E0Y A;  1E7C A;  2EFH A;  1MM8 A;  2EFC A;  3ECP A;  4TQ0 A;  4L9K A;  2XW0 A;  2AGH B;  2DG5 A;  4OT2 A;  3M99 C;  4EMX A;  1HK3 A;  4G04 A;  3WHR A;  3SIU B;  2DBW A;  4IW1 A;  3WHS A;  3V03 A;  4N0F D;  3NMU A;  1NT2 B;  4L8U A;  4ZBQ A;  4Z69 A;  5HOZ A;  4FIP B;  1GNI A;  3SIV B;  2QM6 A;  3GA9 L;  4ZCG A;  5BPK A;  1MIW A;  4F5U A;  4I9O A;  4LB9 A;  2BXQ A;  4FK5 B;  3VQI A;  5IFO A;  2K0N A;  4G01 A;  3MHS B;  5ID7 A;  4Z9O A;  4BKE A;  1HA2 A;  4DHX B;  5FUO A;  2VUE A;  4LA0 A;  3CX9 A;  2GUT A;  1TF0 A;  2NNW A;  2DYM A;  4C31 B;  4N0U D;  4G03 A;  4NAW B;  4K2C A;  3UIV A;  3WHQ A;  5DBY A;  5ID9 A;  3GQU A;  3H3A A;  1MUS A;  5D7G A;  4HGM B;  3FNM A;  1E7B A;  4GG2 A;  2Z8I A;  1JNB A;  2LQI A;  5IJE A;  3PLA A;  4FJC B;  2LXT A;  3NVM A;  4F5T A;  1SB0 A;  2OZB B;  3V08 A;  1VFI A;  4N3Z A;  4F5S A;  1E7H A;  2EFE A;  3A75 A;  1MIY A;  1BKE A;  2YDF A;  2BX8 A; 
#chains in the Genus database with same CATH homology
 2BXF A;  3A73 A;  2BXN A;  1HK5 A;  2BXH A;  4LB2 A;  1E7A A;  2BXP A;  1LOT A;  1E7G A;  3ICX A;  3JQZ A;  1HK2 A;  2XVQ A;  2NQO A;  4OTU A;  3LU7 A;  4S1Y A;  3MHH B;  3G9K D;  1KW2 A;  1O9X A;  4IW2 A;  4J2V A;  2V36 A;  2BXA A;  4ZBK A;  3TDL A;  2QHB A;  4HGK A;  4GDL B;  4ZBR A;  2BXC A;  2E0X A;  2I2Z A;  3B9L A;  4W4U B;  1E78 A;  3SQJ A;  4F5V A;  1HK4 A;  1J7E A;  1TXU A;  2BXI A;  2DYO A;  2VUF A;  2XVW A;  4GDK B;  5GIP A;  1GNJ A;  1FOU A;  1HK1 A;  2CKX A;  4OR0 A;  2BXO A;  4ZUX V;  3NVI A;  3GQX A;  4JK4 A;  1N5U A;  4OTT A;  4LUF A;  2I30 A;  4LUH A;  1J78 A;  4PO0 A;  1BJ5 A;  1E7I A;  2KBZ A;  3LU6 A;  1LNS A;  2DBX A;  5IJF A;  4MBE C;  2DBU A;  3V09 A;  5GIO A;  1IJG A;  2BXE A;  2AJE A;  4GDX A;  3H37 A;  5IIH A;  3KIK A;  2LOQ A;  1H9Z A;  2OT3 A;  5GHK A;  1VZS A;  1E7E A;  5IJ5 A;  2BXM A;  2BXK A;  2BXD A;  4TQ1 A;  2EFD A;  4BY9 C;  1UOR A;  2XVV A;  2ROH A;  1AO6 A;  1H5W A;  2XVU A;  2XW1 A;  2JUH A;  1E7F A;  2BXB A;  3B9M A;  5B5T A;  4M70 B;  2Z8J A;  3JRY A;  3FWC C;  4E99 A;  1MIV A;  2XMO A;  5IIU A;  5DQF A;  1BM0 A;  2VDB A;  2BXG A;  3KJL A;  1MA9 A;  3LU8 A;  3W1S A;  3FWB C;  4K71 A;  4L9Q A;  4WA6 B;  3NVK A;  5IIX A;  2BXL A;  2XSI A;  1KXP D;  2Z8K A;  2QMC A;  4ZC6 A;  5GIN A;  2E0Y A;  1E7C A;  2EFH A;  2EFC A;  4TQ0 A;  4L9K A;  2XW0 A;  2DG5 A;  4OT2 A;  3M99 C;  4EMX A;  1HK3 A;  4G04 A;  3WHR A;  3SIU B;  2DBW A;  4IW1 A;  3WHS A;  3V03 A;  4N0F D;  3NMU A;  1NT2 B;  4L8U A;  4ZBQ A;  4Z69 A;  5HOZ A;  4FIP B;  1GNI A;  3SIV B;  2QM6 A;  3GA9 L;  4ZCG A;  5BPK A;  1MIW A;  4F5U A;  4LB9 A;  2BXQ A;  4FK5 B;  3VQI A;  5IFO A;  4G01 A;  3MHS B;  5ID7 A;  4Z9O A;  4BKE A;  1HA2 A;  4DHX B;  5FUO A;  2VUE A;  4LA0 A;  3CX9 A;  1TF0 A;  2NNW A;  2DYM A;  4C31 B;  4N0U D;  4G03 A;  4NAW B;  4K2C A;  3UIV A;  3WHQ A;  5DBY A;  5ID9 A;  3GQU A;  3H3A A;  5D7G A;  4HGM B;  3FNM A;  1E7B A;  4GG2 A;  2Z8I A;  1JNB A;  5IJE A;  3PLA A;  4FJC B;  3NVM A;  4F5T A;  2OZB B;  3V08 A;  1VFI A;  4N3Z A;  4F5S A;  1E7H A;  2EFE A;  3A75 A;  1MIY A;  1BKE A;  2YDF A;  2BX8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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