3UIVA

Human serum albumin-myristate-amantadine hydrochloride complex
Total Genus 223
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
223
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the drug-binding specificity of human serum albumin
rcsb
molecule tags Lipid binding protein
molecule keywords Serum albumin
total genus 223
structure length 582
sequence length 582
chains with identical sequence H
ec nomenclature
pdb deposition date 2011-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA05
2I30A 4N0FD 2BX8A 4S1YA 5FUOA 1KXPD 4ZBRA 5IFOA 1O9XA 1GNJA 1N5UA 4JK4A 4LA0A 2I2ZA 1GNIA 4F5SA 5IJFA 2BXFA 4F5UA 4EMXA 4G03A 2BXQA 2BXHA 2BXIA 4F5TA 2XW0A 2BXMA 4IW1A 4PO0A 3B9LA 5IJ5A 4IW2A 2XVQA 4J2VA 3UIVA 4L9QA 4F5VA 2XVVA 4ZBQA 1HK3A 4OT2A 2XVUA 2BXLA 3V08A 3TDLA 1E7HA 4E99A 1E7IA 4K71A 1E7CA 5HOZA 5ID7A 1E7FA 4HGMB 3A73A 2VUEA 4BKEA 1HK2A 3SQJA 1E7GA 4LB2A 2BXDA 4LUFA 5IIHA 5DQFA 2BXAA 5IIUA 2BXNA 1J7EA 2BXKA 1HK4A 1AO6A 2BXOA 1BKEA 2XVWA 4OR0A 2XSIA 3JQZA 3JRYA 1HA2A 5ID9A 5IIXA 2XW1A 1E7EA 4G04A 2YDFA 4Z69A 2BXGA 4N0UD 3V09A 1E78A 4L9KA 1LOTA 1KW2A 1BM0A 2BXPA 4LUHA 2VUFA 1H9ZA 1HK1A 3CX9A 1E7BA 2BXBA 3LU6A 1UORA 3LU7A 1E7AA 5IJEA 1TF0A 3LU8A 1BJ5A 5DBYA 4LB9A 3B9MA 2BXCA 3V03A 1HK5A 4HGKA 4K2CA 4L8UA 2BXEA 1MA9A 1J78A 2VDBA 5GHKA
chains in the Genus database with same CATH superfamily
4FJCB 2I30A 4GDLB 1MIWA 2EFHA 4GDXA 4N0FD 2BX8A 4S1YA 2DBUA 1KXPD 4ZBRA 5FUOA 4DM0A 3ECPA 5IFOA 1O9XA 3ICXA 2QHBA 1GNJA 1N5UA 3KIKA 4BY9C 2DYMA 4JK4A 2DBWA 2QMCA 4LA0A 2I2ZA 1GNIA 2AJEA 2XMOA 3W1SA 2KBZA 4F5SA 5IJFA 2BXFA 4F5UA 4C31B 1MUSA 2DBXA 4EMXA 1IJGA 4G03A 3A75A 2BXQA 2BXHA 2BXIA 4TQ1A 3MHSB 4F5TA 2EFCA 2XW0A 3SIUB 2BXMA 4IW1A 4PO0A 5GIPA 2E0XA 2EFEA 4W4UB 3B9LA 1FOUA 2KWFA 5IJ5A 4IW2A 4MBEC 2LOQA 2XVQA 4FIPB 4J2VA 3UIVA 4L9QA 1LNSA 4F5VA 5B5TA 2XVVA 4ZBQA 2Z8JA 1HK3A 4OT2A 2CKXA 2XVUA 1JNBA 2BXLA 3V08A 4GG2A 1MIVA 1VZSA 3TDLA 2E0YA 1E7HA 2AGHB 4NAWB 2OZBB 4E99A 4OTTA 2DG5A 1E7IA 3GQUA 4K71A 1E7CA 2OT3A 5HOZA 2EFDA 1TXUA 4DHXB 3G9KD 3GQXA 5ID7A 4ZBKA 3FWBC 2V36A 1E7FA 4HGMB 2NQOA 3A73A 2VUEA 4BKEA 1SB0A 1NT2B 1HK2A 2LQIA 4TQ0A 2DYOA 5GINA 4WA6B 3SQJA 1E7GA 4LB2A 2BXDA 2JUHA 3H37A 3KJLA 3FNMA 4LUFA 2BXAA 2NNWA 5DQFA 3WHSA 5IIHA 3H3AA 2LXSA 5IIUA 1VFIA 2BXNA 2GUTA 1J7EA 2BXKA 1HK4A 1AO6A 3BPJA 2BXOA 2LXTA 4G01A 1BKEA 2XVWA 4OR0A 3MHHB 2XSIA 4ZC6A 3JQZA 3JRYA 1HA2A 4Z9OA 5ID9A 5IIXA 1MM8A 2XW1A 1E7EA 4G04A 2YDFA 4Z69A 4M70B 2BXGA 3GA9L 4N0UD 3V09A 1E78A 2Z8KA 3M99C 1H5WA 4N3ZA 4L9KA 3FWCC 5GIOA 1LOTA 1KW2A 1BM0A 3NMUA 2BXPA 3NVMA 4LUHA 3WHRA 4ZCGA 2VUFA 1H9ZA 1HK1A 4I9OA 4OTUA 5BPKA 3CX9A 4D7XA 1E7BA 2BXBA 3LU6A 4ZUXV 3PLAA 2K0NA 1UORA 3LU7A 1E7AA 5IJEA 1MUHA 1TF0A 1MIYA 3WHQA 3LU8A 1BJ5A 4FK5B 4GDKB 4LB9A 3B9MA 5DBYA 3VQIA 2BXCA 3SIVB 1KDXA 3V03A 3NVIA 2LQHA 1HK5A 4HGKA 4K2CA 3NVKA 4L8UA 2BXEA 1MA9A 1J78A 2VDBA 2Z8IA 5D7GA 5GHKA 2ROHA 2QM6A
chains in the Genus database with same CATH topology
4FJCB 2I30A 4GDLB 1MIWA 2EFHA 4GDXA 4N0FD 2BX8A 4S1YA 2DBUA 1KXPD 4ZBRA 5FUOA 5IFOA 1O9XA 3ICXA 2QHBA 1GNJA 1N5UA 3KIKA 4BY9C 2DYMA 4JK4A 2DBWA 2QMCA 4LA0A 2I2ZA 1GNIA 2AJEA 2XMOA 3W1SA 2KBZA 4F5SA 5IJFA 2BXFA 4F5UA 4C31B 2DBXA 4EMXA 1IJGA 4G03A 3A75A 2BXQA 2BXHA 2BXIA 4TQ1A 3MHSB 4F5TA 2EFCA 2XW0A 3SIUB 2BXMA 4IW1A 4PO0A 5GIPA 2E0XA 2EFEA 4W4UB 3B9LA 1FOUA 5IJ5A 4IW2A 4MBEC 2LOQA 2XVQA 4FIPB 4J2VA 3UIVA 4L9QA 1LNSA 4F5VA 5B5TA 2XVVA 4ZBQA 2Z8JA 1HK3A 4OT2A 2CKXA 2XVUA 1JNBA 2BXLA 3V08A 4GG2A 1MIVA 1VZSA 3TDLA 2E0YA 1E7HA 2OZBB 4NAWB 4E99A 4OTTA 2DG5A 1E7IA 3GQUA 4K71A 1E7CA 2OT3A 5HOZA 2EFDA 1TXUA 4DHXB 3G9KD 3GQXA 5ID7A 4ZBKA 3FWBC 2V36A 1E7FA 4HGMB 2NQOA 3A73A 2VUEA 4BKEA 1NT2B 1HK2A 4TQ0A 2DYOA 5GINA 4WA6B 3SQJA 1E7GA 4LB2A 2BXDA 2JUHA 3H37A 3KJLA 3FNMA 4LUFA 2BXAA 2NNWA 5DQFA 3WHSA 5IIHA 3H3AA 5IIUA 1VFIA 2BXNA 1J7EA 2BXKA 1HK4A 1AO6A 2BXOA 4G01A 1BKEA 2XVWA 4OR0A 3MHHB 2XSIA 4ZC6A 3JQZA 3JRYA 1HA2A 4Z9OA 5ID9A 5IIXA 2XW1A 1E7EA 4G04A 2YDFA 4Z69A 4M70B 2BXGA 3GA9L 4N0UD 3V09A 1E78A 2Z8KA 3M99C 1H5WA 4N3ZA 4L9KA 3FWCC 5GIOA 1LOTA 1KW2A 1BM0A 3NMUA 2BXPA 3NVMA 4LUHA 3WHRA 4ZCGA 2VUFA 1H9ZA 1HK1A 4OTUA 5BPKA 3CX9A 1E7BA 2BXBA 3LU6A 4ZUXV 3PLAA 1UORA 3LU7A 1E7AA 5IJEA 1TF0A 1MIYA 3WHQA 3LU8A 1BJ5A 4FK5B 4GDKB 4LB9A 3B9MA 5DBYA 3VQIA 2BXCA 3SIVB 3V03A 3NVIA 1HK5A 4HGKA 4K2CA 3NVKA 4L8UA 2BXEA 1MA9A 1J78A 2VDBA 2Z8IA 5D7GA 5GHKA 2ROHA 2QM6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I30 A;  4N0F D;  2BX8 A;  4S1Y A;  5FUO A;  1KXP D;  4ZBR A;  5IFO A;  1O9X A;  1GNJ A;  1N5U A;  4JK4 A;  4LA0 A;  2I2Z A;  1GNI A;  4F5S A;  5IJF A;  2BXF A;  4F5U A;  4EMX A;  4G03 A;  2BXQ A;  2BXH A;  2BXI A;  4F5T A;  2XW0 A;  2BXM A;  4IW1 A;  4PO0 A;  3B9L A;  5IJ5 A;  4IW2 A;  2XVQ A;  4J2V A;  3UIV A;  4L9Q A;  4F5V A;  2XVV A;  4ZBQ A;  1HK3 A;  4OT2 A;  2XVU A;  2BXL A;  3V08 A;  3TDL A;  1E7H A;  4E99 A;  1E7I A;  4K71 A;  1E7C A;  5HOZ A;  5ID7 A;  1E7F A;  4HGM B;  3A73 A;  2VUE A;  4BKE A;  1HK2 A;  3SQJ A;  1E7G A;  4LB2 A;  2BXD A;  4LUF A;  5IIH A;  5DQF A;  2BXA A;  5IIU A;  2BXN A;  1J7E A;  2BXK A;  1HK4 A;  1AO6 A;  2BXO A;  1BKE A;  2XVW A;  4OR0 A;  2XSI A;  3JQZ A;  3JRY A;  1HA2 A;  5ID9 A;  5IIX A;  2XW1 A;  1E7E A;  4G04 A;  2YDF A;  4Z69 A;  2BXG A;  4N0U D;  3V09 A;  1E78 A;  4L9K A;  1LOT A;  1KW2 A;  1BM0 A;  2BXP A;  4LUH A;  2VUF A;  1H9Z A;  1HK1 A;  3CX9 A;  1E7B A;  2BXB A;  3LU6 A;  1UOR A;  3LU7 A;  1E7A A;  5IJE A;  1TF0 A;  3LU8 A;  1BJ5 A;  5DBY A;  4LB9 A;  3B9M A;  2BXC A;  3V03 A;  1HK5 A;  4HGK A;  4K2C A;  4L8U A;  2BXE A;  1MA9 A;  1J78 A;  2VDB A;  5GHK A; 
#chains in the Genus database with same CATH topology
 4FJC B;  2I30 A;  4GDL B;  1MIW A;  2EFH A;  4GDX A;  4N0F D;  2BX8 A;  4S1Y A;  2DBU A;  1KXP D;  4ZBR A;  5FUO A;  4DM0 A;  3ECP A;  5IFO A;  1O9X A;  3ICX A;  2QHB A;  1GNJ A;  1N5U A;  3KIK A;  4BY9 C;  2DYM A;  4JK4 A;  2DBW A;  2QMC A;  4LA0 A;  2I2Z A;  1GNI A;  2AJE A;  2XMO A;  3W1S A;  2KBZ A;  4F5S A;  5IJF A;  2BXF A;  4F5U A;  4C31 B;  1MUS A;  2DBX A;  4EMX A;  1IJG A;  4G03 A;  3A75 A;  2BXQ A;  2BXH A;  2BXI A;  4TQ1 A;  3MHS B;  4F5T A;  2EFC A;  2XW0 A;  3SIU B;  2BXM A;  4IW1 A;  4PO0 A;  5GIP A;  2E0X A;  2EFE A;  4W4U B;  3B9L A;  1FOU A;  2KWF A;  5IJ5 A;  4IW2 A;  4MBE C;  2LOQ A;  2XVQ A;  4FIP B;  4J2V A;  3UIV A;  4L9Q A;  1LNS A;  4F5V A;  5B5T A;  2XVV A;  4ZBQ A;  2Z8J A;  1HK3 A;  4OT2 A;  2CKX A;  2XVU A;  1JNB A;  2BXL A;  3V08 A;  4GG2 A;  1MIV A;  1VZS A;  3TDL A;  2E0Y A;  1E7H A;  2AGH B;  4NAW B;  2OZB B;  4E99 A;  4OTT A;  2DG5 A;  1E7I A;  3GQU A;  4K71 A;  1E7C A;  2OT3 A;  5HOZ A;  2EFD A;  1TXU A;  4DHX B;  3G9K D;  3GQX A;  5ID7 A;  4ZBK A;  3FWB C;  2V36 A;  1E7F A;  4HGM B;  2NQO A;  3A73 A;  2VUE A;  4BKE A;  1SB0 A;  1NT2 B;  1HK2 A;  2LQI A;  4TQ0 A;  2DYO A;  5GIN A;  4WA6 B;  3SQJ A;  1E7G A;  4LB2 A;  2BXD A;  2JUH A;  3H37 A;  3KJL A;  3FNM A;  4LUF A;  2BXA A;  2NNW A;  5DQF A;  3WHS A;  5IIH A;  3H3A A;  2LXS A;  5IIU A;  1VFI A;  2BXN A;  2GUT A;  1J7E A;  2BXK A;  1HK4 A;  1AO6 A;  3BPJ A;  2BXO A;  2LXT A;  4G01 A;  1BKE A;  2XVW A;  4OR0 A;  3MHH B;  2XSI A;  4ZC6 A;  3JQZ A;  3JRY A;  1HA2 A;  4Z9O A;  5ID9 A;  5IIX A;  1MM8 A;  2XW1 A;  1E7E A;  4G04 A;  2YDF A;  4Z69 A;  4M70 B;  2BXG A;  3GA9 L;  4N0U D;  3V09 A;  1E78 A;  2Z8K A;  3M99 C;  1H5W A;  4N3Z A;  4L9K A;  3FWC C;  5GIO A;  1LOT A;  1KW2 A;  1BM0 A;  3NMU A;  2BXP A;  3NVM A;  4LUH A;  3WHR A;  4ZCG A;  2VUF A;  1H9Z A;  1HK1 A;  4I9O A;  4OTU A;  5BPK A;  3CX9 A;  4D7X A;  1E7B A;  2BXB A;  3LU6 A;  4ZUX V;  3PLA A;  2K0N A;  1UOR A;  3LU7 A;  1E7A A;  5IJE A;  1MUH A;  1TF0 A;  1MIY A;  3WHQ A;  3LU8 A;  1BJ5 A;  4FK5 B;  4GDK B;  4LB9 A;  3B9M A;  5DBY A;  3VQI A;  2BXC A;  3SIV B;  1KDX A;  3V03 A;  3NVI A;  2LQH A;  1HK5 A;  4HGK A;  4K2C A;  3NVK A;  4L8U A;  2BXE A;  1MA9 A;  1J78 A;  2VDB A;  2Z8I A;  5D7G A;  5GHK A;  2ROH A;  2QM6 A; 
#chains in the Genus database with same CATH homology
 4FJC B;  2I30 A;  4GDL B;  1MIW A;  2EFH A;  4GDX A;  4N0F D;  2BX8 A;  4S1Y A;  2DBU A;  1KXP D;  4ZBR A;  5FUO A;  5IFO A;  1O9X A;  3ICX A;  2QHB A;  1GNJ A;  1N5U A;  3KIK A;  4BY9 C;  2DYM A;  4JK4 A;  2DBW A;  2QMC A;  4LA0 A;  2I2Z A;  1GNI A;  2AJE A;  2XMO A;  3W1S A;  2KBZ A;  4F5S A;  5IJF A;  2BXF A;  4F5U A;  4C31 B;  2DBX A;  4EMX A;  1IJG A;  4G03 A;  3A75 A;  2BXQ A;  2BXH A;  2BXI A;  4TQ1 A;  3MHS B;  4F5T A;  2EFC A;  2XW0 A;  3SIU B;  2BXM A;  4IW1 A;  4PO0 A;  5GIP A;  2E0X A;  2EFE A;  4W4U B;  3B9L A;  1FOU A;  5IJ5 A;  4IW2 A;  4MBE C;  2LOQ A;  2XVQ A;  4FIP B;  4J2V A;  3UIV A;  4L9Q A;  1LNS A;  4F5V A;  5B5T A;  2XVV A;  4ZBQ A;  2Z8J A;  1HK3 A;  4OT2 A;  2CKX A;  2XVU A;  1JNB A;  2BXL A;  3V08 A;  4GG2 A;  1MIV A;  1VZS A;  3TDL A;  2E0Y A;  1E7H A;  2OZB B;  4NAW B;  4E99 A;  4OTT A;  2DG5 A;  1E7I A;  3GQU A;  4K71 A;  1E7C A;  2OT3 A;  5HOZ A;  2EFD A;  1TXU A;  4DHX B;  3G9K D;  3GQX A;  5ID7 A;  4ZBK A;  3FWB C;  2V36 A;  1E7F A;  4HGM B;  2NQO A;  3A73 A;  2VUE A;  4BKE A;  1NT2 B;  1HK2 A;  4TQ0 A;  2DYO A;  5GIN A;  4WA6 B;  3SQJ A;  1E7G A;  4LB2 A;  2BXD A;  2JUH A;  3H37 A;  3KJL A;  3FNM A;  4LUF A;  2BXA A;  2NNW A;  5DQF A;  3WHS A;  5IIH A;  3H3A A;  5IIU A;  1VFI A;  2BXN A;  1J7E A;  2BXK A;  1HK4 A;  1AO6 A;  2BXO A;  4G01 A;  1BKE A;  2XVW A;  4OR0 A;  3MHH B;  2XSI A;  4ZC6 A;  3JQZ A;  3JRY A;  1HA2 A;  4Z9O A;  5ID9 A;  5IIX A;  2XW1 A;  1E7E A;  4G04 A;  2YDF A;  4Z69 A;  4M70 B;  2BXG A;  3GA9 L;  4N0U D;  3V09 A;  1E78 A;  2Z8K A;  3M99 C;  1H5W A;  4N3Z A;  4L9K A;  3FWC C;  5GIO A;  1LOT A;  1KW2 A;  1BM0 A;  3NMU A;  2BXP A;  3NVM A;  4LUH A;  3WHR A;  4ZCG A;  2VUF A;  1H9Z A;  1HK1 A;  4OTU A;  5BPK A;  3CX9 A;  1E7B A;  2BXB A;  3LU6 A;  4ZUX V;  3PLA A;  1UOR A;  3LU7 A;  1E7A A;  5IJE A;  1TF0 A;  1MIY A;  3WHQ A;  3LU8 A;  1BJ5 A;  4FK5 B;  4GDK B;  4LB9 A;  3B9M A;  5DBY A;  3VQI A;  2BXC A;  3SIV B;  3V03 A;  3NVI A;  1HK5 A;  4HGK A;  4K2C A;  3NVK A;  4L8U A;  2BXE A;  1MA9 A;  1J78 A;  2VDB A;  2Z8I A;  5D7G A;  5GHK A;  2ROH A;  2QM6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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