3UIV | Genus

Total Genus 223

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	223
sequence length	582
structure length	582
Chain Sequence	HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structural basis of the drug-binding specificity of human serum albumin rcsb
molecule keywords	Serum albumin
molecule tags	Lipid binding protein
total genus	223
structure length	582
sequence length	582
chains with identical sequence	H
ec nomenclature
pdb deposition date	2011-11-06

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3uivA03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3uivA02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3uivA04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3uivA01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3uivA06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	3uivA05

1E78A 4HGMB 5IFOA 3JQZA 1LOTA 2BXFA 1E7EA 2BXQA 1BJ5A 3V03A 4PO0A 4G04A 4F5SA 2BXOA 3LU7A 4G03A 4LUFA 2BXMA 4LB2A 5DBYA 1O9XA 5HOZA 4EMXA 3B9LA 2BXNA 1J7EA 1GNJA 4LA0A 5IIXA 4N0UD 4F5TA 4F5VA 3V09A 1HK5A 1KXPD 1E7AA 4LB9A 2BXLA 2XW1A 5ID7A 1HK1A 4OT2A 3CX9A 2XW0A 2XVQA 2BXPA 2BXBA 2BXHA 1KW2A 4ZBRA 1GNIA 5IJFA 4L9KA 1BM0A 5DQFA 5FUOA 1BKEA 3UIVA 1AO6A 4ZBQA 2I2ZA 4N0FD 2BXKA 1E7GA 4J2VA 1N5UA 2VUFA 5ID9A 3SQJA 5IIUA 2VUEA 1HA2A 4HGKA 5IJ5A 3LU8A 2BXGA 4F5UA 5IJEA 2XVVA 3V08A 2BXEA 3A73A 3LU6A 4BKEA 3TDLA 2XSIA 5GHKA 4K2CA 1TF0A 2BXAA 4IW1A 4E99A 2YDFA 3JRYA 1E7IA 1E7CA 2BXCA 4L8UA 5IIHA 2BXDA 4OR0A 4S1YA 4L9QA 1MA9A 2XVUA 4K71A 1UORA 1HK3A 1E7FA 4Z69A 4LUHA 1J78A 1HK4A 2BXIA 1HK2A 3B9MA 4IW2A 4JK4A 1E7HA 2I30A 1H9ZA 2BX8A 2XVWA 1E7BA 2VDBA
chains in the Genus database with same CATH superfamily

3NMUA 2Z8IA 3GA9L 1E78A 4HGMB 2ROHA 5IFOA 3JQZA 2DBUA 1LOTA 2DBXA 5GINA 2DYOA 2BXFA 1E7EA 4ZCGA 2BXQA 4N3ZA 1MUSA 3GQXA 3H3AA 2CKXA 1BJ5A 3V03A 4PO0A 4G04A 5B5TA 2KBZA 4F5SA 4WA6B 2BXOA 3LU7A 4M70B 3A75A 4G03A 4ZC6A 4LUFA 2BXMA 4LB2A 1KDXA 5DBYA 2LQHA 3SIUB 3NVIA 1O9XA 2NQOA 5HOZA 4EMXA 3BPJA 1TXUA 3B9LA 2LXSA 2BXNA 1J7EA 1MIVA 3ECPA 1GNJA 2OZBB 2QMCA 4LA0A 4GDKB 5IIXA 4ZBKA 2NNWA 4N0UD 4F5TA 4F5VA 3V09A 1HK5A 1KXPD 1E7AA 4LB9A 2BXLA 4D7XA 2Z8JA 2XW1A 5ID7A 1HK1A 4OT2A 1FOUA 3CX9A 2XW0A 2XVQA 2BXPA 1MIWA 2BXBA 2BXHA 1KW2A 3SIVB 4ZBRA 3FWCC 1GNIA 2EFHA 3W1SA 2JUHA 1BM0A 4L9KA 5DQFA 5FUOA 4FK5B 5IJFA 4C31B 2AGHB 2LOQA 4DHXB 1BKEA 4Z9OA 3UIVA 3WHSA 4G01A 4TQ0A 2DG5A 1AO6A 1IJGA 2I2ZA 4ZBQA 2K0NA 4GG2A 1MIYA 4N0FD 2BXKA 2DBWA 1E7GA 3MHSB 4J2VA 5GIPA 1MM8A 1N5UA 2VUFA 5ID9A 2E0YA 1VFIA 2V36A 3SQJA 5IIUA 2LQIA 1LNSA 2VUEA 4MBEC 3NVMA 4GDLB 1HA2A 4HGKA 4OTTA 2QM6A 5IJ5A 2AJEA 4NAWB 2XMOA 5BPKA 3LU8A 4OTUA 2BXGA 3M99C 4F5UA 4TQ1A 5IJEA 2XVVA 3NVKA 3PLAA 3V08A 2BXEA 3A73A 3LU6A 4BKEA 3TDLA 4GDXA 2XSIA 5GHKA 1NT2B 4K2CA 1VZSA 1TF0A 2BXAA 3G9KD 3ICXA 4IW1A 1SB0A 2EFEA 1JNBA 3H37A 4E99A 2YDFA 2OT3A 4BY9C 3JRYA 1E7IA 1E7CA 4FJCB 2BXCA 3FNMA 2QHBA 4L8UA 5IIHA 2BXDA 4OR0A 1MUHA 4ZUXV 4S1YA 4L9QA 3VQIA 1MA9A 2EFDA 2GUTA 2LXTA 2XVUA 3KIKA 1UORA 1HK3A 4K71A 3WHRA 2Z8KA 3FWBC 4DM0A 5GIOA 1E7FA 4Z69A 4LUHA 1J78A 3WHQA 1HK4A 3GQUA 2BXIA 1HK2A 2EFCA 2KWFA 3KJLA 3B9MA 4FIPB 4IW2A 4JK4A 1E7HA 4W4UB 1H5WA 2I30A 1H9ZA 2BX8A 2XVWA 4I9OA 3MHHB 2E0XA 1E7BA 2DYMA 5D7GA 2VDBA
chains in the Genus database with same CATH topology

3NMUA 2Z8IA 3GA9L 1E78A 4HGMB 2ROHA 5IFOA 3JQZA 2DBUA 1LOTA 2DBXA 5GINA 2DYOA 2BXFA 1E7EA 4ZCGA 2BXQA 4N3ZA 3GQXA 3H3AA 2CKXA 1BJ5A 3V03A 4PO0A 4G04A 5B5TA 2KBZA 4F5SA 4WA6B 2BXOA 3LU7A 4M70B 3A75A 4G03A 4ZC6A 4LUFA 2BXMA 4LB2A 5DBYA 3SIUB 3NVIA 1O9XA 2NQOA 5HOZA 4EMXA 1TXUA 3B9LA 2BXNA 1J7EA 1MIVA 2OZBB 1GNJA 2QMCA 4LA0A 4GDKB 5IIXA 4ZBKA 2NNWA 4N0UD 4F5TA 4F5VA 3V09A 1HK5A 1KXPD 1E7AA 4LB9A 2BXLA 2Z8JA 2XW1A 5ID7A 1HK1A 4OT2A 1FOUA 3CX9A 2XW0A 2XVQA 2BXPA 1MIWA 2BXBA 2BXHA 1KW2A 3SIVB 4ZBRA 3FWCC 1GNIA 2EFHA 3W1SA 2JUHA 1BM0A 4L9KA 5DQFA 5FUOA 4FK5B 5IJFA 4C31B 2LOQA 4DHXB 1BKEA 4Z9OA 3UIVA 3WHSA 4G01A 4TQ0A 2DG5A 1AO6A 1IJGA 2I2ZA 4ZBQA 4GG2A 1MIYA 4N0FD 2BXKA 2DBWA 1E7GA 3MHSB 4J2VA 5GIPA 1N5UA 2VUFA 5ID9A 2E0YA 1VFIA 2V36A 3SQJA 5IIUA 2VUEA 1LNSA 4MBEC 3NVMA 4GDLB 1HA2A 4HGKA 4OTTA 2QM6A 5IJ5A 2AJEA 4NAWB 2XMOA 5BPKA 3LU8A 4OTUA 2BXGA 3M99C 4F5UA 4TQ1A 5IJEA 2XVVA 3NVKA 3PLAA 3V08A 2BXEA 3A73A 3LU6A 4BKEA 3TDLA 4GDXA 2XSIA 5GHKA 1NT2B 4K2CA 1VZSA 1TF0A 2BXAA 3G9KD 3ICXA 4IW1A 2EFEA 1JNBA 3H37A 4E99A 2YDFA 2OT3A 4BY9C 3JRYA 1E7IA 1E7CA 4FJCB 2BXCA 3FNMA 2QHBA 4L8UA 5IIHA 2BXDA 4OR0A 4ZUXV 4S1YA 4L9QA 3VQIA 1MA9A 2EFDA 2XVUA 3KIKA 4K71A 3WHRA 1UORA 1HK3A 2Z8KA 3FWBC 5GIOA 1E7FA 4Z69A 4LUHA 1J78A 3WHQA 1HK4A 3GQUA 2BXIA 1HK2A 2EFCA 3KJLA 3B9MA 4FIPB 4IW2A 4JK4A 1E7HA 4W4UB 1H5WA 2I30A 1H9ZA 2BX8A 2XVWA 3MHHB 2E0XA 1E7BA 2DYMA 5D7GA 2VDBA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1E78 A;  4HGM B;  5IFO A;  3JQZ A;  1LOT A;  2BXF A;  1E7E A;  2BXQ A;  1BJ5 A;  3V03 A;  4PO0 A;  4G04 A;  4F5S A;  2BXO A;  3LU7 A;  4G03 A;  4LUF A;  2BXM A;  4LB2 A;  5DBY A;  1O9X A;  5HOZ A;  4EMX A;  3B9L A;  2BXN A;  1J7E A;  1GNJ A;  4LA0 A;  5IIX A;  4N0U D;  4F5T A;  4F5V A;  3V09 A;  1HK5 A;  1KXP D;  1E7A A;  4LB9 A;  2BXL A;  2XW1 A;  5ID7 A;  1HK1 A;  4OT2 A;  3CX9 A;  2XW0 A;  2XVQ A;  2BXP A;  2BXB A;  2BXH A;  1KW2 A;  4ZBR A;  1GNI A;  5IJF A;  4L9K A;  1BM0 A;  5DQF A;  5FUO A;  1BKE A;  3UIV A;  1AO6 A;  4ZBQ A;  2I2Z A;  4N0F D;  2BXK A;  1E7G A;  4J2V A;  1N5U A;  2VUF A;  5ID9 A;  3SQJ A;  5IIU A;  2VUE A;  1HA2 A;  4HGK A;  5IJ5 A;  3LU8 A;  2BXG A;  4F5U A;  5IJE A;  2XVV A;  3V08 A;  2BXE A;  3A73 A;  3LU6 A;  4BKE A;  3TDL A;  2XSI A;  5GHK A;  4K2C A;  1TF0 A;  2BXA A;  4IW1 A;  4E99 A;  2YDF A;  3JRY A;  1E7I A;  1E7C A;  2BXC A;  4L8U A;  5IIH A;  2BXD A;  4OR0 A;  4S1Y A;  4L9Q A;  1MA9 A;  2XVU A;  4K71 A;  1UOR A;  1HK3 A;  1E7F A;  4Z69 A;  4LUH A;  1J78 A;  1HK4 A;  2BXI A;  1HK2 A;  3B9M A;  4IW2 A;  4JK4 A;  1E7H A;  2I30 A;  1H9Z A;  2BX8 A;  2XVW A;  1E7B A;  2VDB A; 
#chains in the Genus database with same CATH topology
 3NMU A;  2Z8I A;  3GA9 L;  1E78 A;  4HGM B;  2ROH A;  5IFO A;  3JQZ A;  2DBU A;  1LOT A;  2DBX A;  5GIN A;  2DYO A;  2BXF A;  1E7E A;  4ZCG A;  2BXQ A;  4N3Z A;  1MUS A;  3GQX A;  3H3A A;  2CKX A;  1BJ5 A;  3V03 A;  4PO0 A;  4G04 A;  5B5T A;  2KBZ A;  4F5S A;  4WA6 B;  2BXO A;  3LU7 A;  4M70 B;  3A75 A;  4G03 A;  4ZC6 A;  4LUF A;  2BXM A;  4LB2 A;  1KDX A;  5DBY A;  2LQH A;  3SIU B;  3NVI A;  1O9X A;  2NQO A;  5HOZ A;  4EMX A;  3BPJ A;  1TXU A;  3B9L A;  2LXS A;  2BXN A;  1J7E A;  1MIV A;  3ECP A;  1GNJ A;  2OZB B;  2QMC A;  4LA0 A;  4GDK B;  5IIX A;  4ZBK A;  2NNW A;  4N0U D;  4F5T A;  4F5V A;  3V09 A;  1HK5 A;  1KXP D;  1E7A A;  4LB9 A;  2BXL A;  4D7X A;  2Z8J A;  2XW1 A;  5ID7 A;  1HK1 A;  4OT2 A;  1FOU A;  3CX9 A;  2XW0 A;  2XVQ A;  2BXP A;  1MIW A;  2BXB A;  2BXH A;  1KW2 A;  3SIV B;  4ZBR A;  3FWC C;  1GNI A;  2EFH A;  3W1S A;  2JUH A;  1BM0 A;  4L9K A;  5DQF A;  5FUO A;  4FK5 B;  5IJF A;  4C31 B;  2AGH B;  2LOQ A;  4DHX B;  1BKE A;  4Z9O A;  3UIV A;  3WHS A;  4G01 A;  4TQ0 A;  2DG5 A;  1AO6 A;  1IJG A;  2I2Z A;  4ZBQ A;  2K0N A;  4GG2 A;  1MIY A;  4N0F D;  2BXK A;  2DBW A;  1E7G A;  3MHS B;  4J2V A;  5GIP A;  1MM8 A;  1N5U A;  2VUF A;  5ID9 A;  2E0Y A;  1VFI A;  2V36 A;  3SQJ A;  5IIU A;  2LQI A;  1LNS A;  2VUE A;  4MBE C;  3NVM A;  4GDL B;  1HA2 A;  4HGK A;  4OTT A;  2QM6 A;  5IJ5 A;  2AJE A;  4NAW B;  2XMO A;  5BPK A;  3LU8 A;  4OTU A;  2BXG A;  3M99 C;  4F5U A;  4TQ1 A;  5IJE A;  2XVV A;  3NVK A;  3PLA A;  3V08 A;  2BXE A;  3A73 A;  3LU6 A;  4BKE A;  3TDL A;  4GDX A;  2XSI A;  5GHK A;  1NT2 B;  4K2C A;  1VZS A;  1TF0 A;  2BXA A;  3G9K D;  3ICX A;  4IW1 A;  1SB0 A;  2EFE A;  1JNB A;  3H37 A;  4E99 A;  2YDF A;  2OT3 A;  4BY9 C;  3JRY A;  1E7I A;  1E7C A;  4FJC B;  2BXC A;  3FNM A;  2QHB A;  4L8U A;  5IIH A;  2BXD A;  4OR0 A;  1MUH A;  4ZUX V;  4S1Y A;  4L9Q A;  3VQI A;  1MA9 A;  2EFD A;  2GUT A;  2LXT A;  2XVU A;  3KIK A;  1UOR A;  1HK3 A;  4K71 A;  3WHR A;  2Z8K A;  3FWB C;  4DM0 A;  5GIO A;  1E7F A;  4Z69 A;  4LUH A;  1J78 A;  3WHQ A;  1HK4 A;  3GQU A;  2BXI A;  1HK2 A;  2EFC A;  2KWF A;  3KJL A;  3B9M A;  4FIP B;  4IW2 A;  4JK4 A;  1E7H A;  4W4U B;  1H5W A;  2I30 A;  1H9Z A;  2BX8 A;  2XVW A;  4I9O A;  3MHH B;  2E0X A;  1E7B A;  2DYM A;  5D7G A;  2VDB A; 
#chains in the Genus database with same CATH homology
 3NMU A;  2Z8I A;  3GA9 L;  1E78 A;  4HGM B;  2ROH A;  5IFO A;  3JQZ A;  2DBU A;  1LOT A;  2DBX A;  5GIN A;  2DYO A;  2BXF A;  1E7E A;  4ZCG A;  2BXQ A;  4N3Z A;  3GQX A;  3H3A A;  2CKX A;  1BJ5 A;  3V03 A;  4PO0 A;  4G04 A;  5B5T A;  2KBZ A;  4F5S A;  4WA6 B;  2BXO A;  3LU7 A;  4M70 B;  3A75 A;  4G03 A;  4ZC6 A;  4LUF A;  2BXM A;  4LB2 A;  5DBY A;  3SIU B;  3NVI A;  1O9X A;  2NQO A;  5HOZ A;  4EMX A;  1TXU A;  3B9L A;  2BXN A;  1J7E A;  1MIV A;  2OZB B;  1GNJ A;  2QMC A;  4LA0 A;  4GDK B;  5IIX A;  4ZBK A;  2NNW A;  4N0U D;  4F5T A;  4F5V A;  3V09 A;  1HK5 A;  1KXP D;  1E7A A;  4LB9 A;  2BXL A;  2Z8J A;  2XW1 A;  5ID7 A;  1HK1 A;  4OT2 A;  1FOU A;  3CX9 A;  2XW0 A;  2XVQ A;  2BXP A;  1MIW A;  2BXB A;  2BXH A;  1KW2 A;  3SIV B;  4ZBR A;  3FWC C;  1GNI A;  2EFH A;  3W1S A;  2JUH A;  1BM0 A;  4L9K A;  5DQF A;  5FUO A;  4FK5 B;  5IJF A;  4C31 B;  2LOQ A;  4DHX B;  1BKE A;  4Z9O A;  3UIV A;  3WHS A;  4G01 A;  4TQ0 A;  2DG5 A;  1AO6 A;  1IJG A;  2I2Z A;  4ZBQ A;  4GG2 A;  1MIY A;  4N0F D;  2BXK A;  2DBW A;  1E7G A;  3MHS B;  4J2V A;  5GIP A;  1N5U A;  2VUF A;  5ID9 A;  2E0Y A;  1VFI A;  2V36 A;  3SQJ A;  5IIU A;  2VUE A;  1LNS A;  4MBE C;  3NVM A;  4GDL B;  1HA2 A;  4HGK A;  4OTT A;  2QM6 A;  5IJ5 A;  2AJE A;  4NAW B;  2XMO A;  5BPK A;  3LU8 A;  4OTU A;  2BXG A;  3M99 C;  4F5U A;  4TQ1 A;  5IJE A;  2XVV A;  3NVK A;  3PLA A;  3V08 A;  2BXE A;  3A73 A;  3LU6 A;  4BKE A;  3TDL A;  4GDX A;  2XSI A;  5GHK A;  1NT2 B;  4K2C A;  1VZS A;  1TF0 A;  2BXA A;  3G9K D;  3ICX A;  4IW1 A;  2EFE A;  1JNB A;  3H37 A;  4E99 A;  2YDF A;  2OT3 A;  4BY9 C;  3JRY A;  1E7I A;  1E7C A;  4FJC B;  2BXC A;  3FNM A;  2QHB A;  4L8U A;  5IIH A;  2BXD A;  4OR0 A;  4ZUX V;  4S1Y A;  4L9Q A;  3VQI A;  1MA9 A;  2EFD A;  2XVU A;  3KIK A;  4K71 A;  3WHR A;  1UOR A;  1HK3 A;  2Z8K A;  3FWB C;  5GIO A;  1E7F A;  4Z69 A;  4LUH A;  1J78 A;  3WHQ A;  1HK4 A;  3GQU A;  2BXI A;  1HK2 A;  2EFC A;  3KJL A;  3B9M A;  4FIP B;  4IW2 A;  4JK4 A;  1E7H A;  4W4U B;  1H5W A;  2I30 A;  1H9Z A;  2BX8 A;  2XVW A;  3MHH B;  2E0X A;  1E7B A;  2DYM A;  5D7G A;  2VDB A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3UIVA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations