3KNTA

Crystal structure of methanocaldococcus jannaschii 8-oxoguanine glycosylase/lyase in complex with 15mer dna containing 8-oxoguanine
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
207
structure length
207
Chain Sequence
MMLIKKIEELKNSEIKDIIDKRIQEFKSFKNKSNEEWFKELCFCILTANFTAEGGIRIQKEIGDGFLTLPREELEEKLKNLGHRFYRKRAEYIVLARRFKNIKDIVESFENEKVAREFLVRNIKGIGYQEASHFLRNVGYDDVAIIDRHILRELYENNYIDEIPKTLSRRKYLEIENILRDIGEEVNLKLSELDLYIWYLRTGKVLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The C-terminal Lysine of Ogg2 DNA Glycosylases is a Major Molecular Determinant for Guanine/8-Oxoguanine Distinction.
pubmed doi rcsb
molecule tags Hydrolase, lyase/dna
source organism Methanocaldococcus jannaschii
molecule keywords N-glycosylase/DNA lyase
total genus 76
structure length 207
sequence length 207
chains with identical sequence B, C, D
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2009-11-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 3kntA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 3kntA01
1XQPA 1WEGA 5AN4A 3CWUA 3D4VA 4E9HA 3I0XA 4B24A 1N3CA 2XHIA 2YG8A 2OFKA 1VRLA 4EJYA 4UOBA 1KG5A 1KEAA 2JHNA 4B22A 1LWYA 1EBMA 1KG3A 1PVSA 3CW7A 1KQJA 4EVVA 2NOHA 1LWVA 3KNTA 4EA5A 2JG6A 3CWSA 4UNFA 1KG2A 4YPHA 1HU0A 1M3QA 4EJZA 1P7MA 3IHOA 4AIAA 1MUNA 2NOFA 2ABKA 1YQKA 1YQRA 1LMZA 4YOQA 4HSBA 5KN8A 4EW0A 1YQMA 3I0WA 1RRQA 1YQLA 3IH7A 4OFHA 1KG6A 1KG4A 4B23A 2NOBA 3OGDA 1NGNA 2NOEA 1MUYA 3G0QA 5CHZA 2I5WA 1PU7A 4EA4A 5DPKA 1DIZA 3CVSA 1FN7A 3FHFA 3CWAA 4OFEA 3F0ZA 1WEFA 4AI4A 4B21A 3OH6A 3FSPA 1MPGA 3N0UA 2OFIA 4E9GA 1WEIA 4AI5A 4DK9A 4EW4A 3N5NX 2NOLA 2H56A 1LWWA 2NOZA 1XG7A 3CWTA 3CVTA 3KTUA 1NKUA 1KO9A 3F10A 2JHJA 1XQOA 1RRSA 1ORNA 1KG7A 4E9EA 4E9FA 1N39A 1ORPA 4PIIA 1PU6A 1N3AA 3S6IA 4OFAA 5KN9A 2NOIA 3FHGA 2YG9A 3OH9A 4YPRA 1M3HA 1P59A 1MUDA 1PU8A
chains in the Genus database with same CATH superfamily
3OYJA 1XQPA 1WEGA 5AN4A 3CWUA 3D4VA 4E9HA 3I0XA 4E7JA 3OS0A 2W03A 4B24A 1N3CA 3OYIA 2XHIA 2YG8A 2OFKA 1VRLA 4EJYA 4UOBA 1KG5A 3OYGA 1KEAA 4BACA 3NNQA 3OYBA 2JHNA 4B22A 1LWYA 1EBMA 1KG3A 3OY9A 4BDYA 1PVSA 3OYEA 3CW7A 1KQJA 4EVVA 2NOHA 4E7KA 3S3OA 1LWVA 3KNTA 5FRNA 4EA5A 2JG6A 3CWSA 4UNFA 5FROA 2V75A 3LCNA 1KG2A 4YPHA 1HU0A 1M3QA 4EJZA 1P7MA 3IHOA 4E7LA 4AIAA 1MUNA 3L2UA 2NOFA 2ABKA 1YQKA 1YQRA 4E7HA 1LMZA 3OS2A 4YOQA 4HSBA 5KN8A 3L2RA 4EW0A 3OYAA 1YQMA 3OYKA 3I0WA 1RRQA 2JPSA 4BE0A 2W04A 1YQLA 3IH7A 3S3MA 4OFHA 1KG6A 1KG4A 4B23A 2NOBA 3OYDA 4BDZA 3OGDA 1NGNA 2NOEA 3VW4A 1MUYA 3G0QA 3S3NA 5CHZA 2I5WA 1PU7A 4BE1A 4EA4A 5DPKA 1DIZA 3CVSA 4BE2A 1FN7A 3OYFA 3FHFA 3CWAA 4OFEA 3F0ZA 5FRMA 1WEFA 4AI4A 4B21A 3OH6A 3FSPA 3OYLA 1MPGA 3N0UA 2OFIA 4E9GA 1WEIA 4AI5A 4DK9A 4EW4A 3N5NX 2NOLA 2H56A 1LWWA 2NOZA 1XG7A 3CWTA 3CVTA 3OYMA 3OYCA 3KTUA 4ZTFA 1NKUA 1KO9A 3F10A 2JHJA 3OYHA 1XQOA 1RRSA 3R2XC 1ORNA 1KG7A 4E9EA 4ZTJA 4IKFA 3L2VA 4E9FA 1N39A 1ORPA 4PIIA 3OS1A 4NZGA 1PU6A 1N3AA 3S6IA 4OFAA 1U84A 5KN9A 3L2QA 3FHGA 4E7IA 2YG9A 3OH9A 2NOIA 3OYNA 4YPRA 3L2WA 1M3HA 1MUDA 1P59A 1PU8A
chains in the Genus database with same CATH topology
1XQPA 1WEGA 5AN4A 3CWUA 3D4VA 4E9HA 3I0XA 4B24A 1N3CA 2XHIA 2YG8A 2OFKA 1VRLA 4EJYA 4UOBA 1KG5A 1KEAA 2JHNA 4B22A 1LWYA 1EBMA 1KG3A 1PVSA 3CW7A 1KQJA 4EVVA 2NOHA 1LWVA 3KNTA 4EA5A 2JG6A 3CWSA 4UNFA 1KG2A 4YPHA 1HU0A 1M3QA 4EJZA 1P7MA 3IHOA 4AIAA 1MUNA 2NOFA 2ABKA 1YQKA 1YQRA 1LMZA 4YOQA 4HSBA 5KN8A 4EW0A 1YQMA 3I0WA 1RRQA 1YQLA 3IH7A 4OFHA 1KG6A 1KG4A 4B23A 2NOBA 3OGDA 1NGNA 2NOEA 1MUYA 3G0QA 5CHZA 2I5WA 1PU7A 4EA4A 5DPKA 1DIZA 3CVSA 1FN7A 3FHFA 3CWAA 4OFEA 3F0ZA 1WEFA 4AI4A 4B21A 3OH6A 3FSPA 1MPGA 3N0UA 2OFIA 4E9GA 1WEIA 4AI5A 4DK9A 4EW4A 3N5NX 2NOLA 2H56A 1LWWA 2NOZA 1XG7A 3CWTA 3CVTA 3KTUA 1NKUA 1KO9A 3F10A 2JHJA 1XQOA 1RRSA 1ORNA 1KG7A 4E9EA 4E9FA 1N39A 1ORPA 4PIIA 1PU6A 1N3AA 3S6IA 4OFAA 5KN9A 2NOIA 3FHGA 2YG9A 3OH9A 4YPRA 1M3HA 1P59A 1MUDA 1PU8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XQP A;  1WEG A;  5AN4 A;  3CWU A;  3D4V A;  4E9H A;  3I0X A;  4B24 A;  1N3C A;  2XHI A;  2YG8 A;  2OFK A;  1VRL A;  4EJY A;  4UOB A;  1KG5 A;  1KEA A;  2JHN A;  4B22 A;  1LWY A;  1EBM A;  1KG3 A;  1PVS A;  3CW7 A;  1KQJ A;  4EVV A;  2NOH A;  1LWV A;  3KNT A;  4EA5 A;  2JG6 A;  3CWS A;  4UNF A;  1KG2 A;  4YPH A;  1HU0 A;  1M3Q A;  4EJZ A;  1P7M A;  3IHO A;  4AIA A;  1MUN A;  2NOF A;  2ABK A;  1YQK A;  1YQR A;  1LMZ A;  4YOQ A;  4HSB A;  5KN8 A;  4EW0 A;  1YQM A;  3I0W A;  1RRQ A;  1YQL A;  3IH7 A;  4OFH A;  1KG6 A;  1KG4 A;  4B23 A;  2NOB A;  3OGD A;  1NGN A;  2NOE A;  1MUY A;  3G0Q A;  5CHZ A;  2I5W A;  1PU7 A;  4EA4 A;  5DPK A;  1DIZ A;  3CVS A;  1FN7 A;  3FHF A;  3CWA A;  4OFE A;  3F0Z A;  1WEF A;  4AI4 A;  4B21 A;  3OH6 A;  3FSP A;  1MPG A;  3N0U A;  2OFI A;  4E9G A;  1WEI A;  4AI5 A;  4DK9 A;  4EW4 A;  3N5N X;  2NOL A;  2H56 A;  1LWW A;  2NOZ A;  1XG7 A;  3CWT A;  3CVT A;  3KTU A;  1NKU A;  1KO9 A;  3F10 A;  2JHJ A;  1XQO A;  1RRS A;  1ORN A;  1KG7 A;  4E9E A;  4E9F A;  1N39 A;  1ORP A;  4PII A;  1PU6 A;  1N3A A;  3S6I A;  4OFA A;  5KN9 A;  2NOI A;  3FHG A;  2YG9 A;  3OH9 A;  4YPR A;  1M3H A;  1P59 A;  1MUD A;  1PU8 A; 
#chains in the Genus database with same CATH topology
 3OYJ A;  1XQP A;  1WEG A;  5AN4 A;  3CWU A;  3D4V A;  4E9H A;  3I0X A;  4E7J A;  3OS0 A;  2W03 A;  4B24 A;  1N3C A;  3OYI A;  2XHI A;  2YG8 A;  2OFK A;  1VRL A;  4EJY A;  4UOB A;  1KG5 A;  3OYG A;  1KEA A;  4BAC A;  3NNQ A;  3OYB A;  2JHN A;  4B22 A;  1LWY A;  1EBM A;  1KG3 A;  3OY9 A;  4BDY A;  1PVS A;  3OYE A;  3CW7 A;  1KQJ A;  4EVV A;  2NOH A;  4E7K A;  3S3O A;  1LWV A;  3KNT A;  5FRN A;  4EA5 A;  2JG6 A;  3CWS A;  4UNF A;  5FRO A;  2V75 A;  3LCN A;  1KG2 A;  4YPH A;  1HU0 A;  1M3Q A;  4EJZ A;  1P7M A;  3IHO A;  4E7L A;  4AIA A;  1MUN A;  3L2U A;  2NOF A;  2ABK A;  1YQK A;  1YQR A;  4E7H A;  1LMZ A;  3OS2 A;  4YOQ A;  4HSB A;  5KN8 A;  3L2R A;  4EW0 A;  3OYA A;  1YQM A;  3OYK A;  3I0W A;  1RRQ A;  2JPS A;  4BE0 A;  2W04 A;  1YQL A;  3IH7 A;  3S3M A;  4OFH A;  1KG6 A;  1KG4 A;  4B23 A;  2NOB A;  3OYD A;  4BDZ A;  3OGD A;  1NGN A;  2NOE A;  3VW4 A;  1MUY A;  3G0Q A;  3S3N A;  5CHZ A;  2I5W A;  1PU7 A;  4BE1 A;  4EA4 A;  5DPK A;  1DIZ A;  3CVS A;  4BE2 A;  1FN7 A;  3OYF A;  3FHF A;  3CWA A;  4OFE A;  3F0Z A;  5FRM A;  1WEF A;  4AI4 A;  4B21 A;  3OH6 A;  3FSP A;  3OYL A;  1MPG A;  3N0U A;  2OFI A;  4E9G A;  1WEI A;  4AI5 A;  4DK9 A;  4EW4 A;  3N5N X;  2NOL A;  2H56 A;  1LWW A;  2NOZ A;  1XG7 A;  3CWT A;  3CVT A;  3OYM A;  3OYC A;  3KTU A;  4ZTF A;  1NKU A;  1KO9 A;  3F10 A;  2JHJ A;  3OYH A;  1XQO A;  1RRS A;  3R2X C;  1ORN A;  1KG7 A;  4E9E A;  4ZTJ A;  4IKF A;  3L2V A;  4E9F A;  1N39 A;  1ORP A;  4PII A;  3OS1 A;  4NZG A;  1PU6 A;  1N3A A;  3S6I A;  4OFA A;  1U84 A;  5KN9 A;  3L2Q A;  3FHG A;  4E7I A;  2YG9 A;  3OH9 A;  2NOI A;  3OYN A;  4YPR A;  3L2W A;  1M3H A;  1MUD A;  1P59 A;  1PU8 A; 
#chains in the Genus database with same CATH homology
 1XQP A;  1WEG A;  5AN4 A;  3CWU A;  3D4V A;  4E9H A;  3I0X A;  4B24 A;  1N3C A;  2XHI A;  2YG8 A;  2OFK A;  1VRL A;  4EJY A;  4UOB A;  1KG5 A;  1KEA A;  2JHN A;  4B22 A;  1LWY A;  1EBM A;  1KG3 A;  1PVS A;  3CW7 A;  1KQJ A;  4EVV A;  2NOH A;  1LWV A;  3KNT A;  4EA5 A;  2JG6 A;  3CWS A;  4UNF A;  1KG2 A;  4YPH A;  1HU0 A;  1M3Q A;  4EJZ A;  1P7M A;  3IHO A;  4AIA A;  1MUN A;  2NOF A;  2ABK A;  1YQK A;  1YQR A;  1LMZ A;  4YOQ A;  4HSB A;  5KN8 A;  4EW0 A;  1YQM A;  3I0W A;  1RRQ A;  1YQL A;  3IH7 A;  4OFH A;  1KG6 A;  1KG4 A;  4B23 A;  2NOB A;  3OGD A;  1NGN A;  2NOE A;  1MUY A;  3G0Q A;  5CHZ A;  2I5W A;  1PU7 A;  4EA4 A;  5DPK A;  1DIZ A;  3CVS A;  1FN7 A;  3FHF A;  3CWA A;  4OFE A;  3F0Z A;  1WEF A;  4AI4 A;  4B21 A;  3OH6 A;  3FSP A;  1MPG A;  3N0U A;  2OFI A;  4E9G A;  1WEI A;  4AI5 A;  4DK9 A;  4EW4 A;  3N5N X;  2NOL A;  2H56 A;  1LWW A;  2NOZ A;  1XG7 A;  3CWT A;  3CVT A;  3KTU A;  1NKU A;  1KO9 A;  3F10 A;  2JHJ A;  1XQO A;  1RRS A;  1ORN A;  1KG7 A;  4E9E A;  4E9F A;  1N39 A;  1ORP A;  4PII A;  1PU6 A;  1N3A A;  3S6I A;  4OFA A;  5KN9 A;  2NOI A;  3FHG A;  2YG9 A;  3OH9 A;  4YPR A;  1M3H A;  1P59 A;  1MUD A;  1PU8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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