The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
193
|
sequence length |
578
|
structure length |
578
|
Chain Sequence |
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions
pubmed doi rcsb |
molecule tags |
Transport protein
|
molecule keywords |
Serum albumin
|
total genus |
193
|
structure length |
578
|
sequence length |
578
|
chains with identical sequence |
B
|
ec nomenclature | |
pdb deposition date | 2010-02-17 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
A | PF00273 | Serum_albumin | Serum albumin family |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Mainly Alpha | Orthogonal Bundle | Serum Albumin; Chain A, Domain 1 | Serum Albumin; Chain A, Domain 1 | ||
Mainly Alpha | Orthogonal Bundle | Serum Albumin; Chain A, Domain 1 | Serum Albumin; Chain A, Domain 1 | ||
Mainly Alpha | Orthogonal Bundle | Serum Albumin; Chain A, Domain 1 | Serum Albumin; Chain A, Domain 1 | ||
Mainly Alpha | Orthogonal Bundle | Serum Albumin; Chain A, Domain 1 | Serum Albumin; Chain A, Domain 1 | ||
Mainly Alpha | Orthogonal Bundle | Serum Albumin; Chain A, Domain 1 | Serum Albumin; Chain A, Domain 1 | ||
Mainly Alpha | Orthogonal Bundle | Serum Albumin; Chain A, Domain 1 | Serum Albumin; Chain A, Domain 1 |
#chains in the Genus database with same CATH superfamily 1HK3 A; 4Z69 A; 4K71 A; 4L8U A; 1J78 A; 2VUF A; 1MA9 A; 2XVU A; 1E7C A; 1BKE A; 2BXB A; 4HGM B; 4L9Q A; 2BXM A; 5IIH A; 2BXO A; 4LA0 A; 3CX9 A; 5ID7 A; 4J2V A; 5IIU A; 2BXC A; 1E7A A; 2BXP A; 2BXN A; 4OT2 A; 5DQF A; 4BKE A; 2I2Z A; 5ID9 A; 1AO6 A; 1N5U A; 2BXQ A; 4LB9 A; 1E7G A; 4F5U A; 2XW1 A; 2VDB A; 1LOT A; 4HGK A; 3SQJ A; 4EMX A; 4N0U D; 1E7I A; 5HOZ A; 1BJ5 A; 4LUF A; 1BM0 A; 5FUO A; 1UOR A; 4S1Y A; 1TF0 A; 3UIV A; 4ZBR A; 3V08 A; 2BXE A; 4F5V A; 3LU8 A; 3B9M A; 2YDF A; 5IJF A; 2BXI A; 2BXL A; 3LU7 A; 4LUH A; 5GHK A; 4G04 A; 1KXP D; 2BXK A; 2XW0 A; 2BX8 A; 5IFO A; 2VUE A; 4PO0 A; 1E7F A; 3LU6 A; 1H9Z A; 4F5S A; 4OR0 A; 1O9X A; 3TDL A; 1HK4 A; 2XVV A; 1E7H A; 4ZBQ A; 5IJE A; 4JK4 A; 1J7E A; 2XSI A; 1HK5 A; 1GNI A; 5DBY A; 4G03 A; 1HA2 A; 3B9L A; 5IJ5 A; 5IIX A; 4LB2 A; 3JQZ A; 4L9K A; 1HK2 A; 2BXF A; 4N0F D; 1E7B A; 1E78 A; 2I30 A; 1GNJ A; 2XVW A; 4E99 A; 3V09 A; 1KW2 A; 4IW1 A; 1E7E A; 2BXD A; 2BXG A; 2BXH A; 4F5T A; 4K2C A; 3JRY A; 3V03 A; 2BXA A; 1HK1 A; 2XVQ A; 3A73 A; 4IW2 A; #chains in the Genus database with same CATH topology 1HK3 A; 2GUT A; 4Z69 A; 4FK5 B; 4K71 A; 2LQI A; 4L8U A; 1SB0 A; 1J78 A; 2VUF A; 1KDX A; 1MA9 A; 2DBX A; 2XVU A; 3MHH B; 1E7C A; 3WHS A; 1BKE A; 4Z9O A; 3NVK A; 2BXB A; 4HGM B; 4L9Q A; 2KWF A; 2BXM A; 3SIV B; 5IIH A; 2BXO A; 2LXS A; 4LA0 A; 3CX9 A; 4ZC6 A; 5ID7 A; 4J2V A; 4C31 B; 5IIU A; 4N3Z A; 4GG2 A; 1MIY A; 2AJE A; 1MUS A; 5BPK A; 2BXC A; 3NMU A; 1E7A A; 2BXP A; 3G9K D; 2BXN A; 4OT2 A; 5DQF A; 2K0N A; 2LXT A; 4BKE A; 2CKX A; 2I2Z A; 5ID9 A; 1AO6 A; 1MIV A; 1N5U A; 2BXQ A; 4LB9 A; 1E7G A; 1FOU A; 1HK1 A; 2QMC A; 2XW1 A; 2DG5 A; 3GA9 L; 4I9O A; 4OTT A; 4F5U A; 4TQ0 A; 2VDB A; 1LOT A; 4ZUX V; 4HGK A; 3NVM A; 3SQJ A; 2ROH A; 3M99 C; 4GDL B; 4EMX A; 2XMO A; 4N0U D; 2NQO A; 1E7I A; 4W4U B; 1BJ5 A; 4LUF A; 1BM0 A; 3KIK A; 5HOZ A; 5FUO A; 1UOR A; 4S1Y A; 1TF0 A; 2OT3 A; 3MHS B; 3UIV A; 5GIO A; 4ZBR A; 3V08 A; 2BXE A; 2Z8J A; 1VFI A; 3PLA A; 4F5V A; 3LU8 A; 3B9M A; 4M70 B; 5D7G A; 2YDF A; 5IJF A; 2BXI A; 1LNS A; 3BPJ A; 4OTU A; 5GIN A; 4ZBK A; 2BXL A; 3LU7 A; 1IJG A; 2EFC A; 4LUH A; 4ZCG A; 2Z8I A; 2LQH A; 5GHK A; 4G04 A; 1TXU A; 1KXP D; 2BXK A; 2XW0 A; 2DYO A; 4MBE C; 3KJL A; 2BX8 A; 5IFO A; 2VUE A; 2AGH B; 3H37 A; 3ECP A; 2EFE A; 3WHQ A; 3FWC C; 4PO0 A; 3SIU B; 1MIW A; 1E7F A; 2DBU A; 4NAW B; 4D7X A; 4BY9 C; 3LU6 A; 1H9Z A; 1VZS A; 4F5S A; 4OR0 A; 3GQU A; 1O9X A; 3TDL A; 3VQI A; 1HK4 A; 2XVV A; 4G01 A; 1E7H A; 4ZBQ A; 5IJE A; 4JK4 A; 4GDK B; 2QHB A; 1NT2 B; 1J7E A; 2XSI A; 1HK5 A; 3NVI A; 3W1S A; 3GQX A; 5B5T A; 1GNI A; 5DBY A; 3A75 A; 4G03 A; 1HA2 A; 2V36 A; 3B9L A; 2JUH A; 2NNW A; 4DHX B; 5IJ5 A; 5IIX A; 4LB2 A; 5GIP A; 2DYM A; 2EFH A; 2QM6 A; 3JQZ A; 1H5W A; 4L9K A; 1HK2 A; 2BXF A; 4N0F D; 2Z8K A; 2DBW A; 1JNB A; 1E7B A; 1E78 A; 2I30 A; 1GNJ A; 4FIP B; 2EFD A; 3FNM A; 2XVW A; 3WHR A; 4DM0 A; 1MUH A; 2KBZ A; 4GDX A; 3FWB C; 4TQ1 A; 4E99 A; 3V09 A; 1KW2 A; 4IW1 A; 1E7E A; 3H3A A; 2OZB B; 2BXD A; 2BXG A; 1MM8 A; 2BXH A; 4F5T A; 4FJC B; 4WA6 B; 2LOQ A; 4K2C A; 3JRY A; 3ICX A; 3V03 A; 2BXA A; 2E0X A; 2E0Y A; 2XVQ A; 3A73 A; 4IW2 A; #chains in the Genus database with same CATH homology 1HK3 A; 4Z69 A; 4FK5 B; 4K71 A; 4L8U A; 1J78 A; 2VUF A; 1MA9 A; 2DBX A; 2XVU A; 3MHH B; 1E7C A; 3WHS A; 1BKE A; 4Z9O A; 3NVK A; 2BXB A; 4HGM B; 4L9Q A; 2BXM A; 3SIV B; 5IIH A; 2BXO A; 4LA0 A; 3CX9 A; 4ZC6 A; 5ID7 A; 4J2V A; 4C31 B; 5IIU A; 4N3Z A; 4GG2 A; 1MIY A; 2AJE A; 5BPK A; 2BXC A; 3NMU A; 1E7A A; 2BXP A; 3G9K D; 2BXN A; 4OT2 A; 5DQF A; 4BKE A; 2CKX A; 2I2Z A; 5ID9 A; 1AO6 A; 1MIV A; 1N5U A; 2BXQ A; 4LB9 A; 1E7G A; 1FOU A; 1HK1 A; 2QMC A; 2XW1 A; 2DG5 A; 3GA9 L; 4OTT A; 4F5U A; 4TQ0 A; 5GIO A; 2VDB A; 1LOT A; 4ZUX V; 4HGK A; 3NVM A; 3SQJ A; 2ROH A; 3M99 C; 4GDL B; 4EMX A; 2XMO A; 4N0U D; 2NQO A; 1E7I A; 4W4U B; 1BJ5 A; 4LUF A; 1BM0 A; 3KIK A; 5HOZ A; 5FUO A; 1UOR A; 4S1Y A; 1TF0 A; 2OT3 A; 3MHS B; 3UIV A; 4ZBR A; 3V08 A; 2BXE A; 2Z8J A; 1VFI A; 3PLA A; 4F5V A; 3LU8 A; 3B9M A; 4M70 B; 5D7G A; 2YDF A; 5IJF A; 2BXI A; 1LNS A; 4OTU A; 5GIN A; 4ZBK A; 2BXL A; 3LU7 A; 1IJG A; 2EFC A; 4LUH A; 4ZCG A; 2Z8I A; 5GHK A; 4G04 A; 1TXU A; 1KXP D; 2BXK A; 2XW0 A; 2DYO A; 4MBE C; 3KJL A; 2BX8 A; 5IFO A; 2VUE A; 3H37 A; 2EFE A; 3WHQ A; 3FWC C; 4PO0 A; 3SIU B; 1MIW A; 1E7F A; 2DBU A; 4NAW B; 4BY9 C; 3LU6 A; 1H9Z A; 1VZS A; 4F5S A; 4OR0 A; 3GQU A; 1O9X A; 3TDL A; 3VQI A; 1HK4 A; 2XVV A; 4G01 A; 1E7H A; 4ZBQ A; 5IJE A; 4JK4 A; 4GDK B; 2QHB A; 1NT2 B; 1J7E A; 2XSI A; 1HK5 A; 3NVI A; 3W1S A; 3GQX A; 5B5T A; 1GNI A; 5DBY A; 3A75 A; 4G03 A; 1HA2 A; 2V36 A; 3B9L A; 2JUH A; 2NNW A; 4DHX B; 5IJ5 A; 5IIX A; 4LB2 A; 5GIP A; 2DYM A; 2EFH A; 2QM6 A; 3JQZ A; 1H5W A; 4L9K A; 1HK2 A; 2BXF A; 4N0F D; 2Z8K A; 2DBW A; 1JNB A; 1E7B A; 1E78 A; 2I30 A; 1GNJ A; 4FIP B; 2EFD A; 3FNM A; 2XVW A; 3WHR A; 2KBZ A; 4GDX A; 3FWB C; 4TQ1 A; 4E99 A; 3V09 A; 1KW2 A; 4IW1 A; 1E7E A; 3H3A A; 2OZB B; 2BXD A; 2BXG A; 2BXH A; 4F5T A; 4FJC B; 4WA6 B; 2LOQ A; 4K2C A; 3JRY A; 3ICX A; 3V03 A; 2BXA A; 2E0X A; 2E0Y A; 2XVQ A; 3A73 A; 4IW2 A;
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