3UIVA

Human serum albumin-myristate-amantadine hydrochloride complex
Total Genus 223
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
223
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the drug-binding specificity of human serum albumin
rcsb
molecule keywords Serum albumin
molecule tags Lipid binding protein
total genus 223
structure length 582
sequence length 582
chains with identical sequence H
ec nomenclature
pdb deposition date 2011-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3uivA05
1E7FA 2VUFA 3V08A 2BX8A 5DBYA 4HGKA 2BXHA 2XW0A 4K2CA 4F5VA 5IFOA 4S1YA 1AO6A 4G03A 3LU6A 2BXMA 1GNJA 3UIVA 2BXIA 2BXCA 4L8UA 3CX9A 1H9ZA 3B9LA 1KXPD 1J7EA 2XVQA 5IJEA 1HA2A 2BXDA 3A73A 3SQJA 3LU8A 4ZBRA 4ZBQA 1E78A 3LU7A 1E7IA 1E7HA 1E7AA 4G04A 4IW2A 4LB2A 4LUHA 3JRYA 3TDLA 1E7EA 2BXLA 2VUEA 1MA9A 1N5UA 2XVUA 4K71A 5IJFA 5IIUA 2I2ZA 2BXAA 4IW1A 4BKEA 4HGMB 1O9XA 4L9QA 1E7CA 1HK1A 2BXKA 5DQFA 5GHKA 1HK2A 2BXPA 5IIHA 4N0FD 2BXGA 2XW1A 4F5UA 5ID7A 1TF0A 1HK5A 4N0UD 4LB9A 3JQZA 2BXEA 5HOZA 3V03A 2BXBA 2BXOA 1GNIA 1LOTA 1E7GA 5ID9A 1HK4A 4F5SA 4OT2A 1BKEA 1HK3A 1J78A 5FUOA 1E7BA 1KW2A 5IJ5A 2BXFA 2BXNA 3V09A 2VDBA 4F5TA 3B9MA 4L9KA 2YDFA 5IIXA 2XVVA 4LUFA 4OR0A 2XSIA 2BXQA 4PO0A 1UORA 2XVWA 4LA0A 4E99A 4JK4A 2I30A 4J2VA 4Z69A 1BJ5A 1BM0A 4EMXA
chains in the Genus database with same CATH superfamily
2E0YA 2XMOA 2E0XA 1E7FA 2VUFA 3A75A 2BX8A 3MHSB 2DBUA 2LXSA 5DBYA 3V08A 2Z8KA 4HGKA 2BXHA 2XW0A 4K2CA 4F5VA 2KBZA 3WHRA 3NVKA 5BPKA 2V36A 5IFOA 4S1YA 1AO6A 2LQIA 4G03A 1IJGA 2NNWA 3LU6A 4WA6B 4C31B 2BXMA 5GIOA 4GDXA 1GNJA 3UIVA 3SIUB 2BXIA 2BXCA 4L8UA 4ZUXV 3CX9A 1H9ZA 3B9LA 3FNMA 1KXPD 1J7EA 2XVQA 4OTTA 5IJEA 1HA2A 4DM0A 4ZCGA 2BXDA 3GA9L 2OZBB 2QMCA 4FIPB 3A73A 4TQ1A 3SQJA 1MIYA 3GQXA 3KJLA 3LU8A 4Z9OA 1VZSA 4ZBRA 2Z8IA 1E78A 3LU7A 4ZBQA 1E7IA 2GUTA 1E7HA 4FJCB 1E7AA 3H3AA 4G04A 4IW2A 2LXTA 4LB2A 4LUHA 3G9KD 4GG2A 3JRYA 3TDLA 4DHXB 4N3ZA 1E7EA 2LQHA 2BXLA 5GINA 1MM8A 2VUEA 3BPJA 4W4UB 1MA9A 2AGHB 1N5UA 2EFCA 2XVUA 2QM6A 4K71A 5IJFA 5IIUA 1MUHA 2LOQA 2I2ZA 2BXAA 1FOUA 4IW1A 4BKEA 4HGMB 1O9XA 4L9QA 4OTUA 5D7GA 1E7CA 1LNSA 1HK1A 2BXKA 5DQFA 2AJEA 5GHKA 1HK2A 3KIKA 2Z8JA 2BXPA 2DYOA 3VQIA 5IIHA 4M70B 4N0FD 2KWFA 2BXGA 2XW1A 3M99C 4G01A 4F5UA 1KDXA 4TQ0A 4BY9C 3WHSA 3MHHB 5ID7A 1TF0A 3GQUA 1HK5A 3H37A 4N0UD 4LB9A 2ROHA 3JQZA 2BXEA 5HOZA 3V03A 2BXBA 2BXOA 1GNIA 2EFHA 3SIVB 2DBXA 3NVIA 3ECPA 1LOTA 1E7GA 3FWCC 5ID9A 1HK4A 4ZC6A 4F5SA 4OT2A 1BKEA 2NQOA 1HK3A 1J78A 2K0NA 5FUOA 1E7BA 1KW2A 4D7XA 5IJ5A 2BXFA 1TXUA 4GDLB 2JUHA 4GDKB 2BXNA 1SB0A 2EFEA 3V09A 2VDBA 1H5WA 4F5TA 2QHBA 2DBWA 2DG5A 5B5TA 3W1SA 3B9MA 1MIVA 4L9KA 2YDFA 5IIXA 2XVVA 4LUFA 4OR0A 3FWBC 3NMUA 5GIPA 2XSIA 3NVMA 2BXQA 2DYMA 4PO0A 1JNBA 1UORA 4NAWB 2XVWA 4ZBKA 1VFIA 4FK5B 2EFDA 4LA0A 4MBEC 4E99A 4JK4A 2OT3A 4I9OA 2I30A 2CKXA 3PLAA 1NT2B 1MIWA 3ICXA 4J2VA 1MUSA 4Z69A 1BJ5A 1BM0A 4EMXA 3WHQA
chains in the Genus database with same CATH topology
2E0YA 2XMOA 2E0XA 1E7FA 2VUFA 3A75A 2BX8A 3MHSB 2DBUA 3V08A 5DBYA 2Z8KA 4HGKA 2BXHA 2XW0A 4K2CA 4F5VA 2KBZA 3WHRA 3NVKA 5BPKA 2V36A 5IFOA 4S1YA 1AO6A 4G03A 1IJGA 2NNWA 3LU6A 4WA6B 4C31B 2BXMA 5GIOA 4GDXA 1GNJA 3UIVA 3SIUB 2BXIA 2BXCA 4L8UA 4ZUXV 3CX9A 1H9ZA 3B9LA 3FNMA 1KXPD 1J7EA 2XVQA 4OTTA 5IJEA 1HA2A 4ZCGA 2BXDA 3GA9L 2OZBB 2QMCA 4FIPB 3A73A 4TQ1A 3SQJA 1MIYA 3GQXA 3KJLA 3LU8A 4Z9OA 1VZSA 4ZBRA 2Z8IA 1E78A 3LU7A 4ZBQA 1E7IA 1E7HA 4FJCB 1E7AA 3H3AA 4G04A 4IW2A 4LB2A 4LUHA 3G9KD 4GG2A 3JRYA 3TDLA 4DHXB 4N3ZA 1E7EA 2BXLA 5GINA 2VUEA 4W4UB 1MA9A 1N5UA 2EFCA 2XVUA 2QM6A 4K71A 5IJFA 5IIUA 2LOQA 2I2ZA 2BXAA 1FOUA 4IW1A 4BKEA 4HGMB 1O9XA 4L9QA 4OTUA 5D7GA 1E7CA 1LNSA 1HK1A 2BXKA 5DQFA 2AJEA 5GHKA 1HK2A 3KIKA 2Z8JA 2BXPA 2DYOA 3VQIA 5IIHA 4M70B 4N0FD 2BXGA 2XW1A 3M99C 4G01A 4F5UA 4TQ0A 4BY9C 3WHSA 3MHHB 5ID7A 1TF0A 3GQUA 1HK5A 3H37A 4N0UD 4LB9A 2ROHA 3JQZA 2BXEA 5HOZA 3V03A 2BXBA 2BXOA 1GNIA 2EFHA 3SIVB 2DBXA 3NVIA 1LOTA 1E7GA 3FWCC 5ID9A 1HK4A 4ZC6A 4F5SA 4OT2A 1BKEA 2NQOA 1HK3A 1J78A 5FUOA 1E7BA 1KW2A 5IJ5A 2BXFA 1TXUA 4GDLB 2JUHA 4GDKB 2BXNA 2EFEA 3V09A 2VDBA 1H5WA 4F5TA 2QHBA 2DBWA 2DG5A 5B5TA 3W1SA 3B9MA 1MIVA 4L9KA 2YDFA 5IIXA 2XVVA 4LUFA 4OR0A 3FWBC 3NMUA 5GIPA 2XSIA 3NVMA 2BXQA 2DYMA 4PO0A 1JNBA 1UORA 4NAWB 2XVWA 4ZBKA 1VFIA 4FK5B 2EFDA 4LA0A 4MBEC 4E99A 4JK4A 2OT3A 2I30A 2CKXA 3PLAA 1NT2B 1MIWA 3ICXA 4J2VA 4Z69A 1BJ5A 1BM0A 4EMXA 3WHQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E7F A;  2VUF A;  3V08 A;  2BX8 A;  5DBY A;  4HGK A;  2BXH A;  2XW0 A;  4K2C A;  4F5V A;  5IFO A;  4S1Y A;  1AO6 A;  4G03 A;  3LU6 A;  2BXM A;  1GNJ A;  3UIV A;  2BXI A;  2BXC A;  4L8U A;  3CX9 A;  1H9Z A;  3B9L A;  1KXP D;  1J7E A;  2XVQ A;  5IJE A;  1HA2 A;  2BXD A;  3A73 A;  3SQJ A;  3LU8 A;  4ZBR A;  4ZBQ A;  1E78 A;  3LU7 A;  1E7I A;  1E7H A;  1E7A A;  4G04 A;  4IW2 A;  4LB2 A;  4LUH A;  3JRY A;  3TDL A;  1E7E A;  2BXL A;  2VUE A;  1MA9 A;  1N5U A;  2XVU A;  4K71 A;  5IJF A;  5IIU A;  2I2Z A;  2BXA A;  4IW1 A;  4BKE A;  4HGM B;  1O9X A;  4L9Q A;  1E7C A;  1HK1 A;  2BXK A;  5DQF A;  5GHK A;  1HK2 A;  2BXP A;  5IIH A;  4N0F D;  2BXG A;  2XW1 A;  4F5U A;  5ID7 A;  1TF0 A;  1HK5 A;  4N0U D;  4LB9 A;  3JQZ A;  2BXE A;  5HOZ A;  3V03 A;  2BXB A;  2BXO A;  1GNI A;  1LOT A;  1E7G A;  5ID9 A;  1HK4 A;  4F5S A;  4OT2 A;  1BKE A;  1HK3 A;  1J78 A;  5FUO A;  1E7B A;  1KW2 A;  5IJ5 A;  2BXF A;  2BXN A;  3V09 A;  2VDB A;  4F5T A;  3B9M A;  4L9K A;  2YDF A;  5IIX A;  2XVV A;  4LUF A;  4OR0 A;  2XSI A;  2BXQ A;  4PO0 A;  1UOR A;  2XVW A;  4LA0 A;  4E99 A;  4JK4 A;  2I30 A;  4J2V A;  4Z69 A;  1BJ5 A;  1BM0 A;  4EMX A; 
#chains in the Genus database with same CATH topology
 2E0Y A;  2XMO A;  2E0X A;  1E7F A;  2VUF A;  3A75 A;  2BX8 A;  3MHS B;  2DBU A;  2LXS A;  5DBY A;  3V08 A;  2Z8K A;  4HGK A;  2BXH A;  2XW0 A;  4K2C A;  4F5V A;  2KBZ A;  3WHR A;  3NVK A;  5BPK A;  2V36 A;  5IFO A;  4S1Y A;  1AO6 A;  2LQI A;  4G03 A;  1IJG A;  2NNW A;  3LU6 A;  4WA6 B;  4C31 B;  2BXM A;  5GIO A;  4GDX A;  1GNJ A;  3UIV A;  3SIU B;  2BXI A;  2BXC A;  4L8U A;  4ZUX V;  3CX9 A;  1H9Z A;  3B9L A;  3FNM A;  1KXP D;  1J7E A;  2XVQ A;  4OTT A;  5IJE A;  1HA2 A;  4DM0 A;  4ZCG A;  2BXD A;  3GA9 L;  2OZB B;  2QMC A;  4FIP B;  3A73 A;  4TQ1 A;  3SQJ A;  1MIY A;  3GQX A;  3KJL A;  3LU8 A;  4Z9O A;  1VZS A;  4ZBR A;  2Z8I A;  1E78 A;  3LU7 A;  4ZBQ A;  1E7I A;  2GUT A;  1E7H A;  4FJC B;  1E7A A;  3H3A A;  4G04 A;  4IW2 A;  2LXT A;  4LB2 A;  4LUH A;  3G9K D;  4GG2 A;  3JRY A;  3TDL A;  4DHX B;  4N3Z A;  1E7E A;  2LQH A;  2BXL A;  5GIN A;  1MM8 A;  2VUE A;  3BPJ A;  4W4U B;  1MA9 A;  2AGH B;  1N5U A;  2EFC A;  2XVU A;  2QM6 A;  4K71 A;  5IJF A;  5IIU A;  1MUH A;  2LOQ A;  2I2Z A;  2BXA A;  1FOU A;  4IW1 A;  4BKE A;  4HGM B;  1O9X A;  4L9Q A;  4OTU A;  5D7G A;  1E7C A;  1LNS A;  1HK1 A;  2BXK A;  5DQF A;  2AJE A;  5GHK A;  1HK2 A;  3KIK A;  2Z8J A;  2BXP A;  2DYO A;  3VQI A;  5IIH A;  4M70 B;  4N0F D;  2KWF A;  2BXG A;  2XW1 A;  3M99 C;  4G01 A;  4F5U A;  1KDX A;  4TQ0 A;  4BY9 C;  3WHS A;  3MHH B;  5ID7 A;  1TF0 A;  3GQU A;  1HK5 A;  3H37 A;  4N0U D;  4LB9 A;  2ROH A;  3JQZ A;  2BXE A;  5HOZ A;  3V03 A;  2BXB A;  2BXO A;  1GNI A;  2EFH A;  3SIV B;  2DBX A;  3NVI A;  3ECP A;  1LOT A;  1E7G A;  3FWC C;  5ID9 A;  1HK4 A;  4ZC6 A;  4F5S A;  4OT2 A;  1BKE A;  2NQO A;  1HK3 A;  1J78 A;  2K0N A;  5FUO A;  1E7B A;  1KW2 A;  4D7X A;  5IJ5 A;  2BXF A;  1TXU A;  4GDL B;  2JUH A;  4GDK B;  2BXN A;  1SB0 A;  2EFE A;  3V09 A;  2VDB A;  1H5W A;  4F5T A;  2QHB A;  2DBW A;  2DG5 A;  5B5T A;  3W1S A;  3B9M A;  1MIV A;  4L9K A;  2YDF A;  5IIX A;  2XVV A;  4LUF A;  4OR0 A;  3FWB C;  3NMU A;  5GIP A;  2XSI A;  3NVM A;  2BXQ A;  2DYM A;  4PO0 A;  1JNB A;  1UOR A;  4NAW B;  2XVW A;  4ZBK A;  1VFI A;  4FK5 B;  2EFD A;  4LA0 A;  4MBE C;  4E99 A;  4JK4 A;  2OT3 A;  4I9O A;  2I30 A;  2CKX A;  3PLA A;  1NT2 B;  1MIW A;  3ICX A;  4J2V A;  1MUS A;  4Z69 A;  1BJ5 A;  1BM0 A;  4EMX A;  3WHQ A; 
#chains in the Genus database with same CATH homology
 2E0Y A;  2XMO A;  2E0X A;  1E7F A;  2VUF A;  3A75 A;  2BX8 A;  3MHS B;  2DBU A;  3V08 A;  5DBY A;  2Z8K A;  4HGK A;  2BXH A;  2XW0 A;  4K2C A;  4F5V A;  2KBZ A;  3WHR A;  3NVK A;  5BPK A;  2V36 A;  5IFO A;  4S1Y A;  1AO6 A;  4G03 A;  1IJG A;  2NNW A;  3LU6 A;  4WA6 B;  4C31 B;  2BXM A;  5GIO A;  4GDX A;  1GNJ A;  3UIV A;  3SIU B;  2BXI A;  2BXC A;  4L8U A;  4ZUX V;  3CX9 A;  1H9Z A;  3B9L A;  3FNM A;  1KXP D;  1J7E A;  2XVQ A;  4OTT A;  5IJE A;  1HA2 A;  4ZCG A;  2BXD A;  3GA9 L;  2OZB B;  2QMC A;  4FIP B;  3A73 A;  4TQ1 A;  3SQJ A;  1MIY A;  3GQX A;  3KJL A;  3LU8 A;  4Z9O A;  1VZS A;  4ZBR A;  2Z8I A;  1E78 A;  3LU7 A;  4ZBQ A;  1E7I A;  1E7H A;  4FJC B;  1E7A A;  3H3A A;  4G04 A;  4IW2 A;  4LB2 A;  4LUH A;  3G9K D;  4GG2 A;  3JRY A;  3TDL A;  4DHX B;  4N3Z A;  1E7E A;  2BXL A;  5GIN A;  2VUE A;  4W4U B;  1MA9 A;  1N5U A;  2EFC A;  2XVU A;  2QM6 A;  4K71 A;  5IJF A;  5IIU A;  2LOQ A;  2I2Z A;  2BXA A;  1FOU A;  4IW1 A;  4BKE A;  4HGM B;  1O9X A;  4L9Q A;  4OTU A;  5D7G A;  1E7C A;  1LNS A;  1HK1 A;  2BXK A;  5DQF A;  2AJE A;  5GHK A;  1HK2 A;  3KIK A;  2Z8J A;  2BXP A;  2DYO A;  3VQI A;  5IIH A;  4M70 B;  4N0F D;  2BXG A;  2XW1 A;  3M99 C;  4G01 A;  4F5U A;  4TQ0 A;  4BY9 C;  3WHS A;  3MHH B;  5ID7 A;  1TF0 A;  3GQU A;  1HK5 A;  3H37 A;  4N0U D;  4LB9 A;  2ROH A;  3JQZ A;  2BXE A;  5HOZ A;  3V03 A;  2BXB A;  2BXO A;  1GNI A;  2EFH A;  3SIV B;  2DBX A;  3NVI A;  1LOT A;  1E7G A;  3FWC C;  5ID9 A;  1HK4 A;  4ZC6 A;  4F5S A;  4OT2 A;  1BKE A;  2NQO A;  1HK3 A;  1J78 A;  5FUO A;  1E7B A;  1KW2 A;  5IJ5 A;  2BXF A;  1TXU A;  4GDL B;  2JUH A;  4GDK B;  2BXN A;  2EFE A;  3V09 A;  2VDB A;  1H5W A;  4F5T A;  2QHB A;  2DBW A;  2DG5 A;  5B5T A;  3W1S A;  3B9M A;  1MIV A;  4L9K A;  2YDF A;  5IIX A;  2XVV A;  4LUF A;  4OR0 A;  3FWB C;  3NMU A;  5GIP A;  2XSI A;  3NVM A;  2BXQ A;  2DYM A;  4PO0 A;  1JNB A;  1UOR A;  4NAW B;  2XVW A;  4ZBK A;  1VFI A;  4FK5 B;  2EFD A;  4LA0 A;  4MBE C;  4E99 A;  4JK4 A;  2OT3 A;  2I30 A;  2CKX A;  3PLA A;  1NT2 B;  1MIW A;  3ICX A;  4J2V A;  4Z69 A;  1BJ5 A;  1BM0 A;  4EMX A;  3WHQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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