4B21A

Unprecedented sculpting of dna at abasic sites by dna glycosylase homolog mag2
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
207
structure length
207
Chain Sequence
SKDSDYKRAEKHLSSIDNKWSSLVKKVGPCTLTPHPEHAPYEGIIRAITSQKLSDAATNSIINKFCTQCSDNDEFPTPKQIMETDVETLHECGFSKLKSQEIHIVAEAALNKQIPSKSEIEKMSEEELMESLSKIKGVKRWTIEMYSIFTLGRLDIMPADDSTLKNEAKEFFGLSSKPQTEEVEKLTKPCKPYRTIAAWYLWQIPKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/dna
source organism Schizosaccharomyces pombe
publication title Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2.
pubmed doi rcsb
molecule keywords PROBABLE DNA-3-METHYLADENINE GLYCOSYLASE 2
total genus 77
structure length 207
sequence length 207
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2012-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 4b21A02
1.10.1670.40 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Endonuclease Iii, domain 2 4b21A01
1KG6A 3F10A 4OFAA 3D4VA 4DK9A 5DPKA 4EA4A 4B24A 1N3AA 1P59A 1MUDA 1PVSA 1KG3A 1KEAA 1XQOA 2XHIA 2JHJA 3IH7A 1KG5A 1N3CA 1KG7A 1M3QA 3N5NX 1RRQA 2NOLA 4EW4A 1LWWA 4AI4A 5CHZA 4YPRA 4YPHA 1YQRA 1PU8A 3G0QA 4AI5A 1YQMA 2H56A 1XQPA 3CWTA 2OFIA 4YOQA 1DIZA 3KTUA 2OFKA 2YG9A 4UNFA 3CW7A 1HU0A 3I0XA 3CVSA 1WEGA 3I0WA 5KN9A 4OFEA 3S6IA 4E9EA 3KNTA 1MUNA 4B22A 3CWUA 2JHNA 1WEIA 1KG4A 1MPGA 3F0ZA 3CWSA 1KG2A 1YQLA 3OH9A 4EA5A 2YG8A 1LWVA 4OFHA 1M3HA 1LWYA 2NOBA 1VRLA 2NOHA 1MUYA 4B21A 1XG7A 1WEFA 3FHGA 4AIAA 2JG6A 3CWAA 2NOZA 1NKUA 1LMZA 2ABKA 2I5WA 4PIIA 1NGNA 4EJZA 3IHOA 1RRSA 4HSBA 5KN8A 3N0UA 4E9GA 1P7MA 2NOFA 3FHFA 4EJYA 3OH6A 3OGDA 4EVVA 4E9FA 2NOEA 4B23A 4EW0A 1YQKA 1N39A 3CVTA 1KO9A 1PU6A 1ORNA 1KQJA 3FSPA 1PU7A 5AN4A 1ORPA 1FN7A 2NOIA 4UOBA 4E9HA 1EBMA
chains in the Genus database with same CATH superfamily
3L2RA 3OS0A 1KG6A 3F10A 3R2XC 4OFAA 3D4VA 4DK9A 5DPKA 4EA4A 3LCNA 4E7JA 4B24A 4BE2A 3OYEA 1N3AA 2W04A 1P59A 1MUDA 1PVSA 1KG3A 1KEAA 1XQOA 2XHIA 2JHJA 3IH7A 3L2QA 4BDZA 3OS1A 1KG5A 1N3CA 1KG7A 3L2WA 1M3QA 3N5NX 1RRQA 4E7KA 2NOLA 4EW4A 1LWWA 4AI4A 5CHZA 4YPRA 5FRMA 4YPHA 4IKFA 3OYAA 3OYKA 3OYBA 3OS2A 1YQRA 1PU8A 3G0QA 5FROA 4AI5A 4BE0A 1YQMA 2H56A 1XQPA 3L2UA 4E7HA 3CWTA 2OFIA 4YOQA 1DIZA 3KTUA 2OFKA 2V75A 3VW4A 2YG9A 4UNFA 4BACA 3S3OA 1HU0A 3CW7A 3I0XA 3CVSA 1WEGA 3I0WA 5KN9A 4OFEA 3S6IA 4E9EA 3KNTA 1MUNA 4B22A 3OYFA 3S3NA 3OYMA 3CWUA 2JHNA 1WEIA 1KG4A 1MPGA 3F0ZA 3CWSA 2JPSA 1KG2A 1YQLA 1U84A 3OH9A 4BDYA 4EA5A 2YG8A 1LWVA 4OFHA 1M3HA 4NZGA 1LWYA 2NOBA 1VRLA 3OYGA 2NOHA 1MUYA 4ZTFA 4B21A 4ZTJA 1XG7A 1WEFA 3FHGA 3S3MA 4AIAA 2JG6A 4E7LA 3CWAA 3L2VA 2NOZA 1NKUA 1LMZA 2ABKA 2I5WA 4PIIA 1NGNA 3OYLA 4EJZA 3IHOA 1RRSA 4HSBA 5FRNA 3OYDA 5KN8A 3N0UA 4E9GA 1P7MA 2NOFA 3OY9A 4E7IA 3NNQA 3FHFA 4EJYA 3OH6A 3OGDA 4EVVA 4E9FA 2NOEA 3OYHA 4B23A 4EW0A 4BE1A 1YQKA 3OYCA 1N39A 2W03A 1KO9A 3CVTA 1PU6A 3OYNA 3OYIA 1ORNA 1KQJA 3FSPA 1PU7A 5AN4A 1ORPA 1FN7A 2NOIA 4UOBA 3OYJA 4E9HA 1EBMA
chains in the Genus database with same CATH topology
1KG6A 3F10A 4OFAA 3D4VA 4DK9A 5DPKA 4EA4A 4B24A 1N3AA 1P59A 1MUDA 1PVSA 1KG3A 1KEAA 1XQOA 2XHIA 2JHJA 3IH7A 1KG5A 1N3CA 1KG7A 1M3QA 3N5NX 1RRQA 2NOLA 4EW4A 1LWWA 4AI4A 5CHZA 4YPRA 4YPHA 1YQRA 1PU8A 3G0QA 4AI5A 1YQMA 2H56A 1XQPA 3CWTA 2OFIA 4YOQA 1DIZA 3KTUA 2OFKA 2YG9A 4UNFA 3CW7A 1HU0A 3I0XA 3CVSA 1WEGA 3I0WA 5KN9A 4OFEA 3S6IA 4E9EA 3KNTA 1MUNA 4B22A 3CWUA 2JHNA 1WEIA 1KG4A 1MPGA 3F0ZA 3CWSA 1KG2A 1YQLA 3OH9A 4EA5A 2YG8A 1LWVA 4OFHA 1M3HA 1LWYA 2NOBA 1VRLA 2NOHA 1MUYA 4B21A 1XG7A 1WEFA 3FHGA 4AIAA 2JG6A 3CWAA 2NOZA 1NKUA 1LMZA 2ABKA 2I5WA 4PIIA 1NGNA 4EJZA 3IHOA 1RRSA 4HSBA 5KN8A 3N0UA 4E9GA 1P7MA 2NOFA 3FHFA 4EJYA 3OH6A 3OGDA 4EVVA 4E9FA 2NOEA 4B23A 4EW0A 1YQKA 1N39A 3CVTA 1KO9A 1PU6A 1ORNA 1KQJA 3FSPA 1PU7A 5AN4A 1ORPA 1FN7A 2NOIA 4UOBA 4E9HA 1EBMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KG6 A;  3F10 A;  4OFA A;  3D4V A;  4DK9 A;  5DPK A;  4EA4 A;  4B24 A;  1N3A A;  1P59 A;  1MUD A;  1PVS A;  1KG3 A;  1KEA A;  1XQO A;  2XHI A;  2JHJ A;  3IH7 A;  1KG5 A;  1N3C A;  1KG7 A;  1M3Q A;  3N5N X;  1RRQ A;  2NOL A;  4EW4 A;  1LWW A;  4AI4 A;  5CHZ A;  4YPR A;  4YPH A;  1YQR A;  1PU8 A;  3G0Q A;  4AI5 A;  1YQM A;  2H56 A;  1XQP A;  3CWT A;  2OFI A;  4YOQ A;  1DIZ A;  3KTU A;  2OFK A;  2YG9 A;  4UNF A;  3CW7 A;  1HU0 A;  3I0X A;  3CVS A;  1WEG A;  3I0W A;  5KN9 A;  4OFE A;  3S6I A;  4E9E A;  3KNT A;  1MUN A;  4B22 A;  3CWU A;  2JHN A;  1WEI A;  1KG4 A;  1MPG A;  3F0Z A;  3CWS A;  1KG2 A;  1YQL A;  3OH9 A;  4EA5 A;  2YG8 A;  1LWV A;  4OFH A;  1M3H A;  1LWY A;  2NOB A;  1VRL A;  2NOH A;  1MUY A;  4B21 A;  1XG7 A;  1WEF A;  3FHG A;  4AIA A;  2JG6 A;  3CWA A;  2NOZ A;  1NKU A;  1LMZ A;  2ABK A;  2I5W A;  4PII A;  1NGN A;  4EJZ A;  3IHO A;  1RRS A;  4HSB A;  5KN8 A;  3N0U A;  4E9G A;  1P7M A;  2NOF A;  3FHF A;  4EJY A;  3OH6 A;  3OGD A;  4EVV A;  4E9F A;  2NOE A;  4B23 A;  4EW0 A;  1YQK A;  1N39 A;  3CVT A;  1KO9 A;  1PU6 A;  1ORN A;  1KQJ A;  3FSP A;  1PU7 A;  5AN4 A;  1ORP A;  1FN7 A;  2NOI A;  4UOB A;  4E9H A;  1EBM A; 
#chains in the Genus database with same CATH topology
 3L2R A;  3OS0 A;  1KG6 A;  3F10 A;  3R2X C;  4OFA A;  3D4V A;  4DK9 A;  5DPK A;  4EA4 A;  3LCN A;  4E7J A;  4B24 A;  4BE2 A;  3OYE A;  1N3A A;  2W04 A;  1P59 A;  1MUD A;  1PVS A;  1KG3 A;  1KEA A;  1XQO A;  2XHI A;  2JHJ A;  3IH7 A;  3L2Q A;  4BDZ A;  3OS1 A;  1KG5 A;  1N3C A;  1KG7 A;  3L2W A;  1M3Q A;  3N5N X;  1RRQ A;  4E7K A;  2NOL A;  4EW4 A;  1LWW A;  4AI4 A;  5CHZ A;  4YPR A;  5FRM A;  4YPH A;  4IKF A;  3OYA A;  3OYK A;  3OYB A;  3OS2 A;  1YQR A;  1PU8 A;  3G0Q A;  5FRO A;  4AI5 A;  4BE0 A;  1YQM A;  2H56 A;  1XQP A;  3L2U A;  4E7H A;  3CWT A;  2OFI A;  4YOQ A;  1DIZ A;  3KTU A;  2OFK A;  2V75 A;  3VW4 A;  2YG9 A;  4UNF A;  4BAC A;  3S3O A;  1HU0 A;  3CW7 A;  3I0X A;  3CVS A;  1WEG A;  3I0W A;  5KN9 A;  4OFE A;  3S6I A;  4E9E A;  3KNT A;  1MUN A;  4B22 A;  3OYF A;  3S3N A;  3OYM A;  3CWU A;  2JHN A;  1WEI A;  1KG4 A;  1MPG A;  3F0Z A;  3CWS A;  2JPS A;  1KG2 A;  1YQL A;  1U84 A;  3OH9 A;  4BDY A;  4EA5 A;  2YG8 A;  1LWV A;  4OFH A;  1M3H A;  4NZG A;  1LWY A;  2NOB A;  1VRL A;  3OYG A;  2NOH A;  1MUY A;  4ZTF A;  4B21 A;  4ZTJ A;  1XG7 A;  1WEF A;  3FHG A;  3S3M A;  4AIA A;  2JG6 A;  4E7L A;  3CWA A;  3L2V A;  2NOZ A;  1NKU A;  1LMZ A;  2ABK A;  2I5W A;  4PII A;  1NGN A;  3OYL A;  4EJZ A;  3IHO A;  1RRS A;  4HSB A;  5FRN A;  3OYD A;  5KN8 A;  3N0U A;  4E9G A;  1P7M A;  2NOF A;  3OY9 A;  4E7I A;  3NNQ A;  3FHF A;  4EJY A;  3OH6 A;  3OGD A;  4EVV A;  4E9F A;  2NOE A;  3OYH A;  4B23 A;  4EW0 A;  4BE1 A;  1YQK A;  3OYC A;  1N39 A;  2W03 A;  1KO9 A;  3CVT A;  1PU6 A;  3OYN A;  3OYI A;  1ORN A;  1KQJ A;  3FSP A;  1PU7 A;  5AN4 A;  1ORP A;  1FN7 A;  2NOI A;  4UOB A;  3OYJ A;  4E9H A;  1EBM A; 
#chains in the Genus database with same CATH homology
 1KG6 A;  3F10 A;  4OFA A;  3D4V A;  4DK9 A;  5DPK A;  4EA4 A;  4B24 A;  1N3A A;  1P59 A;  1MUD A;  1PVS A;  1KG3 A;  1KEA A;  1XQO A;  2XHI A;  2JHJ A;  3IH7 A;  1KG5 A;  1N3C A;  1KG7 A;  1M3Q A;  3N5N X;  1RRQ A;  2NOL A;  4EW4 A;  1LWW A;  4AI4 A;  5CHZ A;  4YPR A;  4YPH A;  1YQR A;  1PU8 A;  3G0Q A;  4AI5 A;  1YQM A;  2H56 A;  1XQP A;  3CWT A;  2OFI A;  4YOQ A;  1DIZ A;  3KTU A;  2OFK A;  2YG9 A;  4UNF A;  3CW7 A;  1HU0 A;  3I0X A;  3CVS A;  1WEG A;  3I0W A;  5KN9 A;  4OFE A;  3S6I A;  4E9E A;  3KNT A;  1MUN A;  4B22 A;  3CWU A;  2JHN A;  1WEI A;  1KG4 A;  1MPG A;  3F0Z A;  3CWS A;  1KG2 A;  1YQL A;  3OH9 A;  4EA5 A;  2YG8 A;  1LWV A;  4OFH A;  1M3H A;  1LWY A;  2NOB A;  1VRL A;  2NOH A;  1MUY A;  4B21 A;  1XG7 A;  1WEF A;  3FHG A;  4AIA A;  2JG6 A;  3CWA A;  2NOZ A;  1NKU A;  1LMZ A;  2ABK A;  2I5W A;  4PII A;  1NGN A;  4EJZ A;  3IHO A;  1RRS A;  4HSB A;  5KN8 A;  3N0U A;  4E9G A;  1P7M A;  2NOF A;  3FHF A;  4EJY A;  3OH6 A;  3OGD A;  4EVV A;  4E9F A;  2NOE A;  4B23 A;  4EW0 A;  1YQK A;  1N39 A;  3CVT A;  1KO9 A;  1PU6 A;  1ORN A;  1KQJ A;  3FSP A;  1PU7 A;  5AN4 A;  1ORP A;  1FN7 A;  2NOI A;  4UOB A;  4E9H A;  1EBM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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