4D7XA

Solution structure of the mediator gall11 kix domain of c. glabrata
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
86
structure length
86
Chain Sequence
MSSKETIPMHQRSQNVAELLTVLMDINKINGGDSTTAEKMKVHAKSFEAALFEKSSSKEEYQKTMKSKIDAMRSTRDKRKRESVGS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction.
pubmed doi rcsb
molecule tags Transcription
source organism Candida glabrata
molecule keywords MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15
total genus 36
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2014-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16987 KIX_2 KIX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.20 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Coactivator CBP, KIX domain 4d7xA00
2AGHB 2LXTA 4D7XA 2K0NA 2LQIA 2KWFA 2LQHA 1SB0A 1KDXA 4I9OA 2LXSA 2GUTA
chains in the Genus database with same CATH superfamily
2AGHB 2XW1A 1BM0A 4F5UA 3NVKA 4GDKB 4S1YA 3V08A 2XW0A 2BXKA 2BXBA 2I2ZA 2Z8KA 4L9QA 1E7EA 5ID9A 2BXIA 4OTUA 5GIOA 4EMXA 2XVVA 1HK4A 4ZC6A 3MHSB 3W1SA 1HK3A 4I9OA 1KW2A 4N0FD 2BXFA 2LQIA 2VUFA 3A75A 1MUSA 4BY9C 5DQFA 3WHQA 1AO6A 3A73A 1MUHA 2BXCA 1FOUA 1J7EA 1KXPD 2DG5A 2EFCA 4IW2A 3NMUA 2XVQA 3PLAA 1E7HA 4ZBRA 2AJEA 5DBYA 3SIVB 4G01A 1HK2A 2E0XA 2LXSA 2JUHA 4FIPB 2BXDA 4G03A 2BXPA 2KBZA 1E7GA 3FNMA 4HGMB 2KWFA 3H3AA 4JK4A 2LOQA 2DBXA 1VFIA 2BX8A 3NVMA 2QMCA 3V03A 3ECPA 2LXTA 2BXEA 5B5TA 4N3ZA 1TXUA 1MA9A 4E99A 1E7IA 5BPKA 2OT3A 3H37A 4OT2A 4ZBQA 1BJ5A 2XSIA 4DM0A 4L8UA 1LNSA 4FJCB 4M70B 2VDBA 1E7AA 5HOZA 1E7CA 4TQ0A 4GDLB 1MIVA 1O9XA 4F5SA 4LA0A 1MM8A 2BXQA 5GHKA 2XVWA 4K2CA 4HGKA 5D7GA 5IJ5A 4ZBKA 3TDLA 2EFDA 4BKEA 1GNJA 3GQXA 2BXMA 1H5WA 4GG2A 4MBEC 1IJGA 4W4UB 5FUOA 2LQHA 2DBWA 1SB0A 1JNBA 3WHSA 3MHHB 4WA6B 4OR0A 4NAWB 1N5UA 2BXNA 1KDXA 4GDXA 1E78A 1NT2B 2VUEA 1E7BA 2BXOA 2GUTA 3KJLA 1TF0A 2DYMA 3CX9A 4Z69A 2DYOA 2BXGA 2Z8JA 4FK5B 2NNWA 4DHXB 3WHRA 3NVIA 1HK5A 3FWCC 4K71A 3B9MA 4Z9OA 2DBUA 3UIVA 3FWBC 4TQ1A 5GINA 2OZBB 3KIKA 5IIUA 2QM6A 3ICXA 3SIUB 3SQJA 1MIYA 4N0UD 2E0YA 2NQOA 4F5VA 2BXAA 1MIWA 5IIXA 2K0NA 3LU6A 1HA2A 3LU8A 4F5TA 5ID7A 2QHBA 3V09A 5GIPA 4ZCGA 3M99C 4OTTA 1GNIA 2XMOA 1J78A 4LUHA 1LOTA 1VZSA 4C31B 5IJFA 3B9LA 4L9KA 4D7XA 2BXLA 5IIHA 3BPJA 3G9KD 3GA9L 2XVUA 2YDFA 4PO0A 4ZUXV 4LB2A 4G04A 2I30A 3GQUA 2ROHA 3JQZA 1UORA 1E7FA 2CKXA 2EFHA 5IJEA 5IFOA 2EFEA 3LU7A 4LB9A 2BXHA 1HK1A 4J2VA 2V36A 3JRYA 1H9ZA 4LUFA 3VQIA 4IW1A 1BKEA 2Z8IA
chains in the Genus database with same CATH topology
2AGHB 2LXTA 4D7XA 2K0NA 2LQIA 2KWFA 2LQHA 1SB0A 1KDXA 4I9OA 2LXSA 2GUTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AGH B;  2LXT A;  4D7X A;  2K0N A;  2LQI A;  2KWF A;  2LQH A;  1SB0 A;  1KDX A;  4I9O A;  2LXS A;  2GUT A; 
#chains in the Genus database with same CATH topology
 2AGH B;  2XW1 A;  1BM0 A;  4F5U A;  3NVK A;  4GDK B;  4S1Y A;  3V08 A;  2XW0 A;  2BXK A;  2BXB A;  2I2Z A;  2Z8K A;  4L9Q A;  1E7E A;  5ID9 A;  2BXI A;  4OTU A;  5GIO A;  4EMX A;  2XVV A;  1HK4 A;  4ZC6 A;  3MHS B;  3W1S A;  1HK3 A;  4I9O A;  1KW2 A;  4N0F D;  2BXF A;  2LQI A;  2VUF A;  3A75 A;  1MUS A;  4BY9 C;  5DQF A;  3WHQ A;  1AO6 A;  3A73 A;  1MUH A;  2BXC A;  1FOU A;  1J7E A;  1KXP D;  2DG5 A;  2EFC A;  4IW2 A;  3NMU A;  2XVQ A;  3PLA A;  1E7H A;  4ZBR A;  2AJE A;  5DBY A;  3SIV B;  4G01 A;  1HK2 A;  2E0X A;  2LXS A;  2JUH A;  4FIP B;  2BXD A;  4G03 A;  2BXP A;  2KBZ A;  1E7G A;  3FNM A;  4HGM B;  2KWF A;  3H3A A;  4JK4 A;  2LOQ A;  2DBX A;  1VFI A;  2BX8 A;  3NVM A;  2QMC A;  3V03 A;  3ECP A;  2LXT A;  2BXE A;  5B5T A;  4N3Z A;  1TXU A;  1MA9 A;  4E99 A;  1E7I A;  5BPK A;  2OT3 A;  3H37 A;  4OT2 A;  4ZBQ A;  1BJ5 A;  2XSI A;  4DM0 A;  4L8U A;  1LNS A;  4FJC B;  4M70 B;  2VDB A;  1E7A A;  5HOZ A;  1E7C A;  4TQ0 A;  4GDL B;  1MIV A;  1O9X A;  4F5S A;  4LA0 A;  1MM8 A;  2BXQ A;  5GHK A;  2XVW A;  4K2C A;  4HGK A;  5D7G A;  5IJ5 A;  4ZBK A;  3TDL A;  2EFD A;  4BKE A;  1GNJ A;  3GQX A;  2BXM A;  1H5W A;  4GG2 A;  4MBE C;  1IJG A;  4W4U B;  5FUO A;  2LQH A;  2DBW A;  1SB0 A;  1JNB A;  3WHS A;  3MHH B;  4WA6 B;  4OR0 A;  4NAW B;  1N5U A;  2BXN A;  1KDX A;  4GDX A;  1E78 A;  1NT2 B;  2VUE A;  1E7B A;  2BXO A;  2GUT A;  3KJL A;  1TF0 A;  2DYM A;  3CX9 A;  4Z69 A;  2DYO A;  2BXG A;  2Z8J A;  4FK5 B;  2NNW A;  4DHX B;  3WHR A;  3NVI A;  1HK5 A;  3FWC C;  4K71 A;  3B9M A;  4Z9O A;  2DBU A;  3UIV A;  3FWB C;  4TQ1 A;  5GIN A;  2OZB B;  3KIK A;  5IIU A;  2QM6 A;  3ICX A;  3SIU B;  3SQJ A;  1MIY A;  4N0U D;  2E0Y A;  2NQO A;  4F5V A;  2BXA A;  1MIW A;  5IIX A;  2K0N A;  3LU6 A;  1HA2 A;  3LU8 A;  4F5T A;  5ID7 A;  2QHB A;  3V09 A;  5GIP A;  4ZCG A;  3M99 C;  4OTT A;  1GNI A;  2XMO A;  1J78 A;  4LUH A;  1LOT A;  1VZS A;  4C31 B;  5IJF A;  3B9L A;  4L9K A;  4D7X A;  2BXL A;  5IIH A;  3BPJ A;  3G9K D;  3GA9 L;  2XVU A;  2YDF A;  4PO0 A;  4ZUX V;  4LB2 A;  4G04 A;  2I30 A;  3GQU A;  2ROH A;  3JQZ A;  1UOR A;  1E7F A;  2CKX A;  2EFH A;  5IJE A;  5IFO A;  2EFE A;  3LU7 A;  4LB9 A;  2BXH A;  1HK1 A;  4J2V A;  2V36 A;  3JRY A;  1H9Z A;  4LUF A;  3VQI A;  4IW1 A;  1BKE A;  2Z8I A; 
#chains in the Genus database with same CATH homology
 2AGH B;  2LXT A;  4D7X A;  2K0N A;  2LQI A;  2KWF A;  2LQH A;  1SB0 A;  1KDX A;  4I9O A;  2LXS A;  2GUT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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