4E99A

Human serum albumin complex with perfluorooctane sulfonate potassium
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
567
structure length
554
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural evidence of perfluorooctane sulfonate transport by human serum albumin
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Serum albumin
total genus 226
structure length 554
sequence length 567
ec nomenclature
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A05
4PO0A 2BXLA 4K2CA 2VUFA 5IJEA 5ID9A 3JRYA 4L9QA 1H9ZA 5DBYA 1HK5A 4LB2A 3V08A 4Z69A 1E7EA 5DQFA 2XVWA 2XSIA 4LB9A 1BM0A 4F5SA 2BXIA 1GNJA 2BXGA 5IFOA 3CX9A 2BXCA 4IW1A 4ZBQA 2BXHA 1GNIA 4HGMB 2BXKA 5IJFA 1LOTA 5IIHA 3UIVA 4J2VA 1J78A 2BXBA 4LA0A 1E7GA 1E7BA 2BXQA 2BX8A 2BXPA 3LU8A 5ID7A 1HK1A 3SQJA 4HGKA 4L8UA 4F5UA 4ZBRA 1HK4A 1BKEA 2YDFA 4LUFA 3B9MA 2I30A 4L9KA 1HA2A 1AO6A 5IIXA 5IIUA 2BXMA 4G04A 1E7IA 3A73A 4EMXA 1TF0A 2XVUA 4K71A 3V09A 2BXEA 3LU7A 4N0UD 4N0FD 2XVQA 4G03A 5FUOA 4IW2A 2XW1A 1N5UA 1O9XA 2VDBA 4BKEA 1KXPD 4LUHA 1E78A 4OT2A 5HOZA 1KW2A 2BXNA 3B9LA 4S1YA 2XVVA 4F5VA 2BXDA 4OR0A 5IJ5A 1E7HA 1BJ5A 4E99A 1UORA 5GHKA 4F5TA 2BXOA 1E7FA 3LU6A 4JK4A 1MA9A 3JQZA 1HK2A 3V03A 1HK3A 2XW0A 1E7AA 3TDLA 2VUEA 1J7EA 1E7CA 2BXFA 2BXAA 2I2ZA
chains in the Genus database with same CATH superfamily
1FOUA 4PO0A 4TQ0A 3GQXA 1VFIA 2BXLA 4K2CA 2VUFA 5IJEA 5ID9A 3JRYA 4L9QA 2EFEA 1H9ZA 1IJGA 5DBYA 5BPKA 1HK5A 4LB2A 3NMUA 2LQHA 2EFHA 3MHHB 4FIPB 1MIWA 1E7EA 5DQFA 3V08A 2XVWA 2XSIA 2Z8KA 4LB9A 1BM0A 1VZSA 4F5SA 2OZBB 4TQ1A 4ZBKA 3A75A 2BXIA 4WA6B 1GNJA 2BXGA 5IFOA 4C31B 4DM0A 3CX9A 4G01A 1JNBA 2BXCA 4GG2A 4I9OA 3NVIA 4IW1A 3PLAA 3WHSA 4ZBQA 4OTTA 2BXHA 2E0YA 5GINA 1GNIA 2DG5A 3SIUB 4HGMB 4ZCGA 4FJCB 4D7XA 2BXKA 5IJFA 1LOTA 3NVMA 3FNMA 5IIHA 2LXSA 3UIVA 4J2VA 1J78A 5GIPA 5GIOA 2BXBA 4LA0A 3ECPA 1E7GA 2LXTA 1MIYA 2GUTA 1E7BA 2BXQA 3GA9L 2Z8JA 2BX8A 2BXPA 2DBUA 3LU8A 5ID7A 1HK1A 3SQJA 2ROHA 4GDXA 4MBEC 2XMOA 4HGKA 3FWCC 3M99C 2QMCA 3FWBC 4OTUA 4L8UA 4F5UA 2DBWA 3KIKA 2Z8IA 4ZBRA 1HK4A 1BKEA 2YDFA 4LUFA 3B9MA 2I30A 4Z9OA 2CKXA 4L9KA 1HA2A 1AO6A 1NT2B 2OT3A 4GDKB 2QHBA 5IIXA 5IIUA 2BXMA 4G04A 2KWFA 1E7IA 3A73A 4W4UB 4EMXA 4ZUXV 3KJLA 3NVKA 1TF0A 2XVUA 4K71A 2QM6A 3V09A 3MHSB 3W1SA 2BXEA 3ICXA 3LU7A 4N0UD 4DHXB 2LOQA 4N0FD 2NQOA 2XVQA 4G03A 2V36A 5FUOA 2AJEA 2JUHA 3VQIA 2LQIA 2K0NA 2XW1A 2VDBA 1N5UA 1O9XA 3G9KD 2NNWA 4IW2A 2EFCA 3H3AA 4BKEA 4Z69A 1MUHA 1KXPD 3BPJA 4LUHA 1E78A 4OT2A 4BY9C 1H5WA 2EFDA 2E0XA 5HOZA 1KW2A 3WHRA 2BXNA 2KBZA 1KDXA 3B9LA 4S1YA 2XVVA 4F5VA 2BXDA 4OR0A 1LNSA 1MIVA 5IJ5A 5B5TA 1E7HA 1BJ5A 4NAWB 3H37A 4E99A 1TXUA 1UORA 2DYMA 4GDLB 1MM8A 2DBXA 5GHKA 4F5TA 2BXOA 3GQUA 2DYOA 1E7FA 3LU6A 4JK4A 1SB0A 1MA9A 3JQZA 4N3ZA 4ZC6A 1MUSA 1HK2A 3V03A 2AGHB 4FK5B 1HK3A 2XW0A 4M70B 3SIVB 1E7AA 3TDLA 2VUEA 5D7GA 3WHQA 1J7EA 1E7CA 2BXFA 2BXAA 2I2ZA
chains in the Genus database with same CATH topology
1FOUA 4PO0A 4TQ0A 3GQXA 1VFIA 2BXLA 4K2CA 2VUFA 5IJEA 5ID9A 3JRYA 4L9QA 2EFEA 1H9ZA 1IJGA 5DBYA 5BPKA 1HK5A 4LB2A 3NMUA 3V08A 2EFHA 3MHHB 4FIPB 1MIWA 1E7EA 5DQFA 4Z69A 2XVWA 2XSIA 2Z8KA 4LB9A 1BM0A 1VZSA 4F5SA 2OZBB 4TQ1A 4ZBKA 3A75A 2BXIA 4WA6B 1GNJA 2BXGA 5IFOA 4C31B 3NVIA 3CX9A 4G01A 1JNBA 2BXCA 4GG2A 3PLAA 4IW1A 3WHSA 4ZBQA 4OTTA 2BXHA 2E0YA 5GINA 1GNIA 2DG5A 3SIUB 4HGMB 4ZCGA 4FJCB 2BXKA 5IJFA 1LOTA 3NVMA 3FNMA 5IIHA 3UIVA 4J2VA 1J78A 5GIPA 5GIOA 2BXBA 4LA0A 1E7GA 1MIYA 1E7BA 2BXQA 3GA9L 2Z8JA 2BX8A 2BXPA 2DBUA 3LU8A 5ID7A 1HK1A 3SQJA 2ROHA 4GDXA 4MBEC 2XMOA 4HGKA 3FWCC 3M99C 2QMCA 3FWBC 4OTUA 4L8UA 4F5UA 2DBWA 3KIKA 2Z8IA 4ZBRA 1HK4A 1BKEA 2YDFA 4LUFA 3B9MA 2I30A 4Z9OA 2CKXA 4L9KA 1HA2A 1AO6A 1NT2B 2OT3A 4GDKB 2QHBA 5IIXA 5IIUA 2BXMA 4G04A 1E7IA 3A73A 4W4UB 4EMXA 4ZUXV 3KJLA 3NVKA 1TF0A 2XVUA 4K71A 2QM6A 3V09A 3MHSB 3W1SA 2BXEA 3ICXA 3LU7A 4N0UD 4DHXB 2LOQA 4N0FD 2NQOA 2XVQA 4G03A 2V36A 5FUOA 2AJEA 2JUHA 3VQIA 2XW1A 2VDBA 1N5UA 1O9XA 3G9KD 2NNWA 4IW2A 2EFCA 3H3AA 4BKEA 3SIVB 1KXPD 4LUHA 1E78A 4OT2A 4BY9C 1H5WA 2EFDA 2E0XA 5HOZA 1KW2A 3WHRA 2BXNA 2KBZA 3B9LA 4S1YA 2XVVA 4F5VA 2BXDA 4OR0A 1LNSA 1MIVA 5IJ5A 5B5TA 1E7HA 1BJ5A 4NAWB 3H37A 4E99A 1TXUA 1UORA 2DYMA 4GDLB 2DBXA 5GHKA 4F5TA 2BXOA 3GQUA 2DYOA 1E7FA 3LU6A 4JK4A 1MA9A 3JQZA 4N3ZA 4ZC6A 1HK2A 3V03A 4FK5B 1HK3A 2XW0A 4M70B 1E7AA 3TDLA 2VUEA 5D7GA 3WHQA 1J7EA 1E7CA 2BXFA 2BXAA 2I2ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PO0 A;  2BXL A;  4K2C A;  2VUF A;  5IJE A;  5ID9 A;  3JRY A;  4L9Q A;  1H9Z A;  5DBY A;  1HK5 A;  4LB2 A;  3V08 A;  4Z69 A;  1E7E A;  5DQF A;  2XVW A;  2XSI A;  4LB9 A;  1BM0 A;  4F5S A;  2BXI A;  1GNJ A;  2BXG A;  5IFO A;  3CX9 A;  2BXC A;  4IW1 A;  4ZBQ A;  2BXH A;  1GNI A;  4HGM B;  2BXK A;  5IJF A;  1LOT A;  5IIH A;  3UIV A;  4J2V A;  1J78 A;  2BXB A;  4LA0 A;  1E7G A;  1E7B A;  2BXQ A;  2BX8 A;  2BXP A;  3LU8 A;  5ID7 A;  1HK1 A;  3SQJ A;  4HGK A;  4L8U A;  4F5U A;  4ZBR A;  1HK4 A;  1BKE A;  2YDF A;  4LUF A;  3B9M A;  2I30 A;  4L9K A;  1HA2 A;  1AO6 A;  5IIX A;  5IIU A;  2BXM A;  4G04 A;  1E7I A;  3A73 A;  4EMX A;  1TF0 A;  2XVU A;  4K71 A;  3V09 A;  2BXE A;  3LU7 A;  4N0U D;  4N0F D;  2XVQ A;  4G03 A;  5FUO A;  4IW2 A;  2XW1 A;  1N5U A;  1O9X A;  2VDB A;  4BKE A;  1KXP D;  4LUH A;  1E78 A;  4OT2 A;  5HOZ A;  1KW2 A;  2BXN A;  3B9L A;  4S1Y A;  2XVV A;  4F5V A;  2BXD A;  4OR0 A;  5IJ5 A;  1E7H A;  1BJ5 A;  4E99 A;  1UOR A;  5GHK A;  4F5T A;  2BXO A;  1E7F A;  3LU6 A;  4JK4 A;  1MA9 A;  3JQZ A;  1HK2 A;  3V03 A;  1HK3 A;  2XW0 A;  1E7A A;  3TDL A;  2VUE A;  1J7E A;  1E7C A;  2BXF A;  2BXA A;  2I2Z A; 
#chains in the Genus database with same CATH topology
 1FOU A;  4PO0 A;  4TQ0 A;  3GQX A;  1VFI A;  2BXL A;  4K2C A;  2VUF A;  5IJE A;  5ID9 A;  3JRY A;  4L9Q A;  2EFE A;  1H9Z A;  1IJG A;  5DBY A;  5BPK A;  1HK5 A;  4LB2 A;  3NMU A;  2LQH A;  2EFH A;  3MHH B;  4FIP B;  1MIW A;  1E7E A;  5DQF A;  3V08 A;  2XVW A;  2XSI A;  2Z8K A;  4LB9 A;  1BM0 A;  1VZS A;  4F5S A;  2OZB B;  4TQ1 A;  4ZBK A;  3A75 A;  2BXI A;  4WA6 B;  1GNJ A;  2BXG A;  5IFO A;  4C31 B;  4DM0 A;  3CX9 A;  4G01 A;  1JNB A;  2BXC A;  4GG2 A;  4I9O A;  3NVI A;  4IW1 A;  3PLA A;  3WHS A;  4ZBQ A;  4OTT A;  2BXH A;  2E0Y A;  5GIN A;  1GNI A;  2DG5 A;  3SIU B;  4HGM B;  4ZCG A;  4FJC B;  4D7X A;  2BXK A;  5IJF A;  1LOT A;  3NVM A;  3FNM A;  5IIH A;  2LXS A;  3UIV A;  4J2V A;  1J78 A;  5GIP A;  5GIO A;  2BXB A;  4LA0 A;  3ECP A;  1E7G A;  2LXT A;  1MIY A;  2GUT A;  1E7B A;  2BXQ A;  3GA9 L;  2Z8J A;  2BX8 A;  2BXP A;  2DBU A;  3LU8 A;  5ID7 A;  1HK1 A;  3SQJ A;  2ROH A;  4GDX A;  4MBE C;  2XMO A;  4HGK A;  3FWC C;  3M99 C;  2QMC A;  3FWB C;  4OTU A;  4L8U A;  4F5U A;  2DBW A;  3KIK A;  2Z8I A;  4ZBR A;  1HK4 A;  1BKE A;  2YDF A;  4LUF A;  3B9M A;  2I30 A;  4Z9O A;  2CKX A;  4L9K A;  1HA2 A;  1AO6 A;  1NT2 B;  2OT3 A;  4GDK B;  2QHB A;  5IIX A;  5IIU A;  2BXM A;  4G04 A;  2KWF A;  1E7I A;  3A73 A;  4W4U B;  4EMX A;  4ZUX V;  3KJL A;  3NVK A;  1TF0 A;  2XVU A;  4K71 A;  2QM6 A;  3V09 A;  3MHS B;  3W1S A;  2BXE A;  3ICX A;  3LU7 A;  4N0U D;  4DHX B;  2LOQ A;  4N0F D;  2NQO A;  2XVQ A;  4G03 A;  2V36 A;  5FUO A;  2AJE A;  2JUH A;  3VQI A;  2LQI A;  2K0N A;  2XW1 A;  2VDB A;  1N5U A;  1O9X A;  3G9K D;  2NNW A;  4IW2 A;  2EFC A;  3H3A A;  4BKE A;  4Z69 A;  1MUH A;  1KXP D;  3BPJ A;  4LUH A;  1E78 A;  4OT2 A;  4BY9 C;  1H5W A;  2EFD A;  2E0X A;  5HOZ A;  1KW2 A;  3WHR A;  2BXN A;  2KBZ A;  1KDX A;  3B9L A;  4S1Y A;  2XVV A;  4F5V A;  2BXD A;  4OR0 A;  1LNS A;  1MIV A;  5IJ5 A;  5B5T A;  1E7H A;  1BJ5 A;  4NAW B;  3H37 A;  4E99 A;  1TXU A;  1UOR A;  2DYM A;  4GDL B;  1MM8 A;  2DBX A;  5GHK A;  4F5T A;  2BXO A;  3GQU A;  2DYO A;  1E7F A;  3LU6 A;  4JK4 A;  1SB0 A;  1MA9 A;  3JQZ A;  4N3Z A;  4ZC6 A;  1MUS A;  1HK2 A;  3V03 A;  2AGH B;  4FK5 B;  1HK3 A;  2XW0 A;  4M70 B;  3SIV B;  1E7A A;  3TDL A;  2VUE A;  5D7G A;  3WHQ A;  1J7E A;  1E7C A;  2BXF A;  2BXA A;  2I2Z A; 
#chains in the Genus database with same CATH homology
 1FOU A;  4PO0 A;  4TQ0 A;  3GQX A;  1VFI A;  2BXL A;  4K2C A;  2VUF A;  5IJE A;  5ID9 A;  3JRY A;  4L9Q A;  2EFE A;  1H9Z A;  1IJG A;  5DBY A;  5BPK A;  1HK5 A;  4LB2 A;  3NMU A;  3V08 A;  2EFH A;  3MHH B;  4FIP B;  1MIW A;  1E7E A;  5DQF A;  4Z69 A;  2XVW A;  2XSI A;  2Z8K A;  4LB9 A;  1BM0 A;  1VZS A;  4F5S A;  2OZB B;  4TQ1 A;  4ZBK A;  3A75 A;  2BXI A;  4WA6 B;  1GNJ A;  2BXG A;  5IFO A;  4C31 B;  3NVI A;  3CX9 A;  4G01 A;  1JNB A;  2BXC A;  4GG2 A;  3PLA A;  4IW1 A;  3WHS A;  4ZBQ A;  4OTT A;  2BXH A;  2E0Y A;  5GIN A;  1GNI A;  2DG5 A;  3SIU B;  4HGM B;  4ZCG A;  4FJC B;  2BXK A;  5IJF A;  1LOT A;  3NVM A;  3FNM A;  5IIH A;  3UIV A;  4J2V A;  1J78 A;  5GIP A;  5GIO A;  2BXB A;  4LA0 A;  1E7G A;  1MIY A;  1E7B A;  2BXQ A;  3GA9 L;  2Z8J A;  2BX8 A;  2BXP A;  2DBU A;  3LU8 A;  5ID7 A;  1HK1 A;  3SQJ A;  2ROH A;  4GDX A;  4MBE C;  2XMO A;  4HGK A;  3FWC C;  3M99 C;  2QMC A;  3FWB C;  4OTU A;  4L8U A;  4F5U A;  2DBW A;  3KIK A;  2Z8I A;  4ZBR A;  1HK4 A;  1BKE A;  2YDF A;  4LUF A;  3B9M A;  2I30 A;  4Z9O A;  2CKX A;  4L9K A;  1HA2 A;  1AO6 A;  1NT2 B;  2OT3 A;  4GDK B;  2QHB A;  5IIX A;  5IIU A;  2BXM A;  4G04 A;  1E7I A;  3A73 A;  4W4U B;  4EMX A;  4ZUX V;  3KJL A;  3NVK A;  1TF0 A;  2XVU A;  4K71 A;  2QM6 A;  3V09 A;  3MHS B;  3W1S A;  2BXE A;  3ICX A;  3LU7 A;  4N0U D;  4DHX B;  2LOQ A;  4N0F D;  2NQO A;  2XVQ A;  4G03 A;  2V36 A;  5FUO A;  2AJE A;  2JUH A;  3VQI A;  2XW1 A;  2VDB A;  1N5U A;  1O9X A;  3G9K D;  2NNW A;  4IW2 A;  2EFC A;  3H3A A;  4BKE A;  3SIV B;  1KXP D;  4LUH A;  1E78 A;  4OT2 A;  4BY9 C;  1H5W A;  2EFD A;  2E0X A;  5HOZ A;  1KW2 A;  3WHR A;  2BXN A;  2KBZ A;  3B9L A;  4S1Y A;  2XVV A;  4F5V A;  2BXD A;  4OR0 A;  1LNS A;  1MIV A;  5IJ5 A;  5B5T A;  1E7H A;  1BJ5 A;  4NAW B;  3H37 A;  4E99 A;  1TXU A;  1UOR A;  2DYM A;  4GDL B;  2DBX A;  5GHK A;  4F5T A;  2BXO A;  3GQU A;  2DYO A;  1E7F A;  3LU6 A;  4JK4 A;  1MA9 A;  3JQZ A;  4N3Z A;  4ZC6 A;  1HK2 A;  3V03 A;  4FK5 B;  1HK3 A;  2XW0 A;  4M70 B;  1E7A A;  3TDL A;  2VUE A;  5D7G A;  3WHQ A;  1J7E A;  1E7C A;  2BXF A;  2BXA A;  2I2Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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