4GDXA

Crystal structure of human gamma-glutamyl transpeptidase--glutamate complex
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
342
structure length
342
Chain Sequence
PDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Gamma-glutamyltranspeptidase 1 heavy chain
total genus 108
structure length 342
sequence length 342
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2012-08-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4gdxA02
2DBXA 3A75A 2E0XA 2DBWA 4OTTA 3FNMA 5B5TA 4GG2A 2QM6A 2Z8JA 2QMCA 4Z9OA 4ZBKA 2E0YA 2NQOA 2V36A 4GDXA 3WHRA 4OTUA 4ZCGA 5BPKA 4ZC6A 2Z8IA 3WHQA 2DG5A 2DBUA 3WHSA 2Z8KA
chains in the Genus database with same CATH superfamily
3A75A 4K71A 5IIUA 2EFCA 4ZBRA 1SB0A 2AJEA 1E78A 2BXHA 1MM8A 1E7EA 4GG2A 4FIPB 1KW2A 5ID7A 3V09A 4L8UA 3H3AA 4EMXA 1E7BA 4Z9OA 2E0YA 1GNJA 5GINA 4HGKA 2BXAA 3TDLA 4FJCB 5IIHA 4IW2A 4GDXA 3H37A 1J78A 4J2VA 5IIXA 2AGHB 2BX8A 3WHRA 4BY9C 2YDFA 4OTUA 2DYMA 4F5VA 2VUEA 3JRYA 1VFIA 3UIVA 3VQIA 3LU8A 3MHHB 3ECPA 4IW1A 1HK1A 2LOQA 2OZBB 1E7IA 4G04A 2Z8KA 3M99C 3GQUA 4NAWB 2ROHA 4DHXB 1GNIA 4Z69A 4ZBQA 3NVIA 5B5TA 4W4UB 1MIVA 2BXKA 1BKEA 2QM6A 1O9XA 1TF0A 3JQZA 3PLAA 1MIYA 4L9QA 1MIWA 1UORA 4LB9A 1MUSA 1BJ5A 2XSIA 3A73A 4FK5B 4D7XA 5HOZA 1LNSA 5IJ5A 2XVVA 5GHKA 1E7GA 4TQ0A 3FWCC 2BXIA 4TQ1A 5DBYA 2XW0A 4F5UA 1NT2B 2BXGA 4HGMB 1HK2A 1HK5A 4LA0A 1E7HA 2BXFA 2XVWA 4G03A 4N0FD 2XVQA 4GDLB 4K2CA 1KXPD 4S1YA 1E7AA 1KDXA 2Z8IA 1JNBA 3B9MA 2DBUA 1N5UA 2DBXA 4JK4A 2E0XA 2I2ZA 4MBEC 4OTTA 2KBZA 1FOUA 4GDKB 4M70B 4E99A 5DQFA 1H9ZA 2JUHA 4LB2A 3G9KD 2Z8JA 2LXTA 5FUOA 4L9KA 2OT3A 4G01A 2BXOA 2NQOA 1MA9A 2V36A 3SIVB 5IFOA 1TXUA 2XMOA 3NVMA 1MUHA 3CX9A 3SIUB 5GIOA 2XW1A 1HK4A 2BXPA 2BXLA 3MHSB 3SQJA 2LQIA 4LUHA 2NNWA 2BXCA 2BXMA 2GUTA 4I9OA 1E7CA 3B9LA 2BXBA 1J7EA 3LU7A 5IJEA 4ZC6A 3WHQA 2LQHA 3LU6A 4N3ZA 3ICXA 3WHSA 4DM0A 1IJGA 4LUFA 3V03A 3GA9L 2DBWA 2VUFA 2CKXA 3FNMA 2EFDA 1HA2A 1BM0A 4C31B 4BKEA 3KIKA 4F5TA 2LXSA 2EFHA 2BXQA 3W1SA 1E7FA 2BXEA 2QMCA 4ZBKA 2K0NA 4ZUXV 3V08A 5IJFA 3KJLA 3NVKA 2BXNA 2VDBA 4F5SA 1AO6A 2DYOA 1H5WA 2XVUA 3GQXA 5GIPA 4OT2A 4N0UD 5D7GA 1VZSA 5ID9A 1LOTA 3BPJA 2KWFA 4ZCGA 3FWBC 4OR0A 5BPKA 2QHBA 2BXDA 4WA6B 2DG5A 2EFEA 4PO0A 1HK3A 2I30A 3NMUA
chains in the Genus database with same CATH topology
3A75A 4K71A 5IIUA 2EFCA 4ZBRA 2AJEA 1E78A 2BXHA 1E7EA 4GG2A 4FIPB 1KW2A 5ID7A 3V09A 4L8UA 3H3AA 4EMXA 1E7BA 4Z9OA 2E0YA 1GNJA 5GINA 4HGKA 2BXAA 3TDLA 4FJCB 5IIHA 4IW2A 4GDXA 3H37A 1J78A 4J2VA 5IIXA 4BY9C 2BX8A 3WHRA 2YDFA 4OTUA 2DYMA 4F5VA 2VUEA 3JRYA 1VFIA 3UIVA 3VQIA 3LU8A 3MHHB 4IW1A 1HK1A 2LOQA 2OZBB 1E7IA 4G04A 2Z8KA 3M99C 3GQUA 4NAWB 2ROHA 4DHXB 1GNIA 4Z69A 4ZBQA 3NVIA 5B5TA 4W4UB 1MIVA 2BXKA 1BKEA 2QM6A 1O9XA 1TF0A 3JQZA 3PLAA 1MIYA 4L9QA 1MIWA 1UORA 4LB9A 1BJ5A 2XSIA 3A73A 4FK5B 5HOZA 1LNSA 5IJ5A 2XVVA 5GHKA 1E7GA 4TQ0A 3FWCC 2BXIA 4TQ1A 5DBYA 2XW0A 4F5UA 1NT2B 2BXGA 4HGMB 1HK2A 1HK5A 4LA0A 1E7HA 2BXFA 2XVWA 4G03A 4N0FD 2XVQA 4GDLB 4K2CA 1KXPD 4S1YA 1E7AA 2Z8IA 1JNBA 3B9MA 2DBUA 1N5UA 2DBXA 4JK4A 2E0XA 2I2ZA 4MBEC 4OTTA 2KBZA 1FOUA 4GDKB 4M70B 4E99A 5DQFA 1H9ZA 2JUHA 4LB2A 3G9KD 2Z8JA 5FUOA 4L9KA 2OT3A 4G01A 2BXOA 2NQOA 1MA9A 2V36A 3SIVB 5IFOA 1TXUA 2XMOA 3NVMA 3SIUB 3CX9A 5GIOA 2XW1A 1HK4A 2BXPA 2BXLA 3MHSB 3SQJA 4LUHA 2NNWA 2BXCA 2BXMA 1E7CA 3B9LA 2BXBA 1J7EA 3LU7A 5IJEA 4ZC6A 3WHQA 3LU6A 4N3ZA 3WHSA 3ICXA 1IJGA 4LUFA 3V03A 3GA9L 2DBWA 2VUFA 2CKXA 3FNMA 2EFDA 1HA2A 1BM0A 4C31B 4BKEA 3KIKA 4F5TA 2EFHA 2BXQA 3W1SA 1E7FA 2BXEA 2QMCA 4ZBKA 4ZUXV 3V08A 5IJFA 3KJLA 3NVKA 2BXNA 2VDBA 4F5SA 1AO6A 2DYOA 1H5WA 2XVUA 3GQXA 5GIPA 4OT2A 4N0UD 5D7GA 1VZSA 5ID9A 1LOTA 4ZCGA 3FWBC 4OR0A 5BPKA 2QHBA 2BXDA 4WA6B 2DG5A 2EFEA 4PO0A 1HK3A 2I30A 3NMUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DBX A;  3A75 A;  2E0X A;  2DBW A;  4OTT A;  3FNM A;  5B5T A;  4GG2 A;  2QM6 A;  2Z8J A;  2QMC A;  4Z9O A;  4ZBK A;  2E0Y A;  2NQO A;  2V36 A;  4GDX A;  3WHR A;  4OTU A;  4ZCG A;  5BPK A;  4ZC6 A;  2Z8I A;  3WHQ A;  2DG5 A;  2DBU A;  3WHS A;  2Z8K A; 
#chains in the Genus database with same CATH topology
 3A75 A;  4K71 A;  5IIU A;  2EFC A;  4ZBR A;  1SB0 A;  2AJE A;  1E78 A;  2BXH A;  1MM8 A;  1E7E A;  4GG2 A;  4FIP B;  1KW2 A;  5ID7 A;  3V09 A;  4L8U A;  3H3A A;  4EMX A;  1E7B A;  4Z9O A;  2E0Y A;  1GNJ A;  5GIN A;  4HGK A;  2BXA A;  3TDL A;  4FJC B;  5IIH A;  4IW2 A;  4GDX A;  3H37 A;  1J78 A;  4J2V A;  5IIX A;  2AGH B;  2BX8 A;  3WHR A;  4BY9 C;  2YDF A;  4OTU A;  2DYM A;  4F5V A;  2VUE A;  3JRY A;  1VFI A;  3UIV A;  3VQI A;  3LU8 A;  3MHH B;  3ECP A;  4IW1 A;  1HK1 A;  2LOQ A;  2OZB B;  1E7I A;  4G04 A;  2Z8K A;  3M99 C;  3GQU A;  4NAW B;  2ROH A;  4DHX B;  1GNI A;  4Z69 A;  4ZBQ A;  3NVI A;  5B5T A;  4W4U B;  1MIV A;  2BXK A;  1BKE A;  2QM6 A;  1O9X A;  1TF0 A;  3JQZ A;  3PLA A;  1MIY A;  4L9Q A;  1MIW A;  1UOR A;  4LB9 A;  1MUS A;  1BJ5 A;  2XSI A;  3A73 A;  4FK5 B;  4D7X A;  5HOZ A;  1LNS A;  5IJ5 A;  2XVV A;  5GHK A;  1E7G A;  4TQ0 A;  3FWC C;  2BXI A;  4TQ1 A;  5DBY A;  2XW0 A;  4F5U A;  1NT2 B;  2BXG A;  4HGM B;  1HK2 A;  1HK5 A;  4LA0 A;  1E7H A;  2BXF A;  2XVW A;  4G03 A;  4N0F D;  2XVQ A;  4GDL B;  4K2C A;  1KXP D;  4S1Y A;  1E7A A;  1KDX A;  2Z8I A;  1JNB A;  3B9M A;  2DBU A;  1N5U A;  2DBX A;  4JK4 A;  2E0X A;  2I2Z A;  4MBE C;  4OTT A;  2KBZ A;  1FOU A;  4GDK B;  4M70 B;  4E99 A;  5DQF A;  1H9Z A;  2JUH A;  4LB2 A;  3G9K D;  2Z8J A;  2LXT A;  5FUO A;  4L9K A;  2OT3 A;  4G01 A;  2BXO A;  2NQO A;  1MA9 A;  2V36 A;  3SIV B;  5IFO A;  1TXU A;  2XMO A;  3NVM A;  1MUH A;  3CX9 A;  3SIU B;  5GIO A;  2XW1 A;  1HK4 A;  2BXP A;  2BXL A;  3MHS B;  3SQJ A;  2LQI A;  4LUH A;  2NNW A;  2BXC A;  2BXM A;  2GUT A;  4I9O A;  1E7C A;  3B9L A;  2BXB A;  1J7E A;  3LU7 A;  5IJE A;  4ZC6 A;  3WHQ A;  2LQH A;  3LU6 A;  4N3Z A;  3ICX A;  3WHS A;  4DM0 A;  1IJG A;  4LUF A;  3V03 A;  3GA9 L;  2DBW A;  2VUF A;  2CKX A;  3FNM A;  2EFD A;  1HA2 A;  1BM0 A;  4C31 B;  4BKE A;  3KIK A;  4F5T A;  2LXS A;  2EFH A;  2BXQ A;  3W1S A;  1E7F A;  2BXE A;  2QMC A;  4ZBK A;  2K0N A;  4ZUX V;  3V08 A;  5IJF A;  3KJL A;  3NVK A;  2BXN A;  2VDB A;  4F5S A;  1AO6 A;  2DYO A;  1H5W A;  2XVU A;  3GQX A;  5GIP A;  4OT2 A;  4N0U D;  5D7G A;  1VZS A;  5ID9 A;  1LOT A;  3BPJ A;  2KWF A;  4ZCG A;  3FWB C;  4OR0 A;  5BPK A;  2QHB A;  2BXD A;  4WA6 B;  2DG5 A;  2EFE A;  4PO0 A;  1HK3 A;  2I30 A;  3NMU A; 
#chains in the Genus database with same CATH homology
 3A75 A;  4K71 A;  5IIU A;  2EFC A;  4ZBR A;  2AJE A;  1E78 A;  2BXH A;  1E7E A;  4GG2 A;  4FIP B;  1KW2 A;  5ID7 A;  3V09 A;  4L8U A;  3H3A A;  4EMX A;  1E7B A;  4Z9O A;  2E0Y A;  1GNJ A;  5GIN A;  4HGK A;  2BXA A;  3TDL A;  4FJC B;  5IIH A;  4IW2 A;  4GDX A;  3H37 A;  1J78 A;  4J2V A;  5IIX A;  4BY9 C;  2BX8 A;  3WHR A;  2YDF A;  4OTU A;  2DYM A;  4F5V A;  2VUE A;  3JRY A;  1VFI A;  3UIV A;  3VQI A;  3LU8 A;  3MHH B;  4IW1 A;  1HK1 A;  2LOQ A;  2OZB B;  1E7I A;  4G04 A;  2Z8K A;  3M99 C;  3GQU A;  4NAW B;  2ROH A;  4DHX B;  1GNI A;  4Z69 A;  4ZBQ A;  3NVI A;  5B5T A;  4W4U B;  1MIV A;  2BXK A;  1BKE A;  2QM6 A;  1O9X A;  1TF0 A;  3JQZ A;  3PLA A;  1MIY A;  4L9Q A;  1MIW A;  1UOR A;  4LB9 A;  1BJ5 A;  2XSI A;  3A73 A;  4FK5 B;  5HOZ A;  1LNS A;  5IJ5 A;  2XVV A;  5GHK A;  1E7G A;  4TQ0 A;  3FWC C;  2BXI A;  4TQ1 A;  5DBY A;  2XW0 A;  4F5U A;  1NT2 B;  2BXG A;  4HGM B;  1HK2 A;  1HK5 A;  4LA0 A;  1E7H A;  2BXF A;  2XVW A;  4G03 A;  4N0F D;  2XVQ A;  4GDL B;  4K2C A;  1KXP D;  4S1Y A;  1E7A A;  2Z8I A;  1JNB A;  3B9M A;  2DBU A;  1N5U A;  2DBX A;  4JK4 A;  2E0X A;  2I2Z A;  4MBE C;  4OTT A;  2KBZ A;  1FOU A;  4GDK B;  4M70 B;  4E99 A;  5DQF A;  1H9Z A;  2JUH A;  4LB2 A;  3G9K D;  2Z8J A;  5FUO A;  4L9K A;  2OT3 A;  4G01 A;  2BXO A;  2NQO A;  1MA9 A;  2V36 A;  3SIV B;  5IFO A;  1TXU A;  2XMO A;  3NVM A;  3SIU B;  3CX9 A;  5GIO A;  2XW1 A;  1HK4 A;  2BXP A;  2BXL A;  3MHS B;  3SQJ A;  4LUH A;  2NNW A;  2BXC A;  2BXM A;  1E7C A;  3B9L A;  2BXB A;  1J7E A;  3LU7 A;  5IJE A;  4ZC6 A;  3WHQ A;  3LU6 A;  4N3Z A;  3WHS A;  3ICX A;  1IJG A;  4LUF A;  3V03 A;  3GA9 L;  2DBW A;  2VUF A;  2CKX A;  3FNM A;  2EFD A;  1HA2 A;  1BM0 A;  4C31 B;  4BKE A;  3KIK A;  4F5T A;  2EFH A;  2BXQ A;  3W1S A;  1E7F A;  2BXE A;  2QMC A;  4ZBK A;  4ZUX V;  3V08 A;  5IJF A;  3KJL A;  3NVK A;  2BXN A;  2VDB A;  4F5S A;  1AO6 A;  2DYO A;  1H5W A;  2XVU A;  3GQX A;  5GIP A;  4OT2 A;  4N0U D;  5D7G A;  1VZS A;  5ID9 A;  1LOT A;  4ZCG A;  3FWB C;  4OR0 A;  5BPK A;  2QHB A;  2BXD A;  4WA6 B;  2DG5 A;  2EFE A;  4PO0 A;  1HK3 A;  2I30 A;  3NMU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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