4HGK | Genus

Total Genus 188

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	188
sequence length	490
structure length	483
Chain Sequence	KSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEV

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Immune system
source organism	Homo sapiens
publication title	Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis. pubmed doi rcsb
molecule keywords	Serum albumin
total genus	188
structure length	483
sequence length	490
chains with identical sequence	B
ec nomenclature
pdb deposition date	2012-10-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4hgkA02

2VUEA 3A73A 2BXHA 1HK4A 4BKEA 1MA9A 4LB9A 2BXLA 3V09A 2BXPA 5IJEA 4L9QA 1HK1A 2XSIA 4IW1A 5DBYA 1BKEA 4OR0A 4HGKA 1J78A 4LA0A 5HOZA 2I2ZA 1N5UA 2I30A 2BXBA 5IFOA 5IIUA 2VUFA 2BXEA 2BXMA 4E99A 3V08A 4LB2A 4F5SA 1AO6A 2BXQA 3LU7A 4ZBQA 2XVQA 4N0UD 4F5UA 1E7IA 3CX9A 2BXKA 1TF0A 1E7EA 2BXCA 5GHKA 2BXOA 1E7CA 1GNIA 4F5VA 5IJFA 1E7BA 1HA2A 1KXPD 5IJ5A 3TDLA 4LUFA 4S1YA 2VDBA 4G04A 5DQFA 4G03A 4L9KA 2BXDA 1HK3A 2BXNA 3JRYA 5ID7A 2BXIA 4K71A 2BXAA 3UIVA 1HK2A 4N0FD 1LOTA 1E7GA 1O9XA 2YDFA 4F5TA 2XW0A 5FUOA 5ID9A 2BXGA 1H9ZA 3LU8A 3LU6A 1E7AA 2BXFA 4IW2A 3JQZA 4JK4A 3V03A 1E7FA 5IIHA 1UORA 3B9MA 4LUHA 2XVWA 1KW2A 4ZBRA 5IIXA 1BM0A 4L8UA 1J7EA 1BJ5A 1HK5A 4J2VA 3B9LA 4K2CA 3SQJA 1GNJA 4OT2A 4Z69A 2XW1A 1E7HA 4PO0A 2XVUA 1E78A 4EMXA 2BX8A 2XVVA 4HGMB
chains in the Genus database with same CATH superfamily

2LQHA 4NAWB 4DM0A 2VUEA 4ZCGA 3A73A 2XVVA 2BXHA 1HK4A 4BKEA 1MA9A 4LB9A 3NVIA 4C31B 2BXLA 2V36A 2GUTA 3V09A 4N3ZA 4G01A 2BXPA 5IJEA 4L9QA 1HK1A 2XSIA 3A75A 4IW1A 4M70B 3H3AA 2NQOA 5DBYA 1BKEA 4OR0A 4HGKA 1J78A 3H37A 3KIKA 4LA0A 2Z8JA 2AJEA 5HOZA 3WHSA 3WHRA 2I2ZA 1N5UA 2I30A 2BXBA 4FJCB 4FK5B 5IFOA 3WHQA 2VUFA 2KBZA 2BXEA 2BXMA 4E99A 1TXUA 5IIUA 3V08A 4GG2A 3BPJA 2QHBA 3NVKA 4LB2A 4F5SA 1AO6A 2BXQA 1MIYA 3LU7A 4ZBQA 2LOQA 2XVQA 4N0UD 2KWFA 2DBXA 4F5UA 1E7IA 2AGHB 2BXKA 1TF0A 1E7EA 3CX9A 1KDXA 3FWBC 2BXCA 2CKXA 3GQUA 5GHKA 2BXOA 1E7CA 1GNIA 3NVMA 4F5VA 5IJFA 1E7BA 1HA2A 1MUSA 3M99C 1KXPD 5IJ5A 2LQIA 3TDLA 4LUFA 2JUHA 4TQ1A 4S1YA 3MHSB 4TQ0A 5GIOA 2DBUA 2VDBA 4G04A 3G9KD 1H5WA 5BPKA 4OTUA 2Z8KA 2QMCA 5DQFA 4G03A 3PLAA 2Z8IA 3ECPA 2E0XA 4L9KA 4BY9C 2BXDA 1HK3A 2BXNA 3JRYA 5ID7A 2OZBB 1MIWA 5GIPA 1FOUA 2EFDA 2BXIA 2EFEA 2EFHA 4K71A 2BXAA 3UIVA 1HK2A 1SB0A 2NNWA 4N0FD 1LNSA 1MIVA 1JNBA 3FNMA 3VQIA 1NT2B 3SIUB 1E7GA 2DBWA 4OTTA 5GINA 4FIPB 1O9XA 4D7XA 2YDFA 4DHXB 4F5TA 2XW0A 5FUOA 2OT3A 2ROHA 4I9OA 5ID9A 2BXGA 1MM8A 1H9ZA 1VZSA 2LXSA 3LU8A 4ZUXV 5D7GA 3LU6A 1E7AA 2E0YA 4GDKB 2BXFA 4IW2A 3JQZA 4JK4A 3V03A 4MBEC 4WA6B 1E7FA 3GA9L 3GQXA 1UORA 3ICXA 4ZC6A 3B9MA 5IIHA 3NMUA 4LUHA 2XVWA 2DYMA 1KW2A 4ZBRA 2LXTA 5IIXA 1BM0A 5B5TA 3KJLA 4GDXA 2XMOA 1J7EA 4L8UA 2EFCA 1BJ5A 1HK5A 2QM6A 4J2VA 3B9LA 1MUHA 4K2CA 3SQJA 1GNJA 4OT2A 4Z69A 4W4UB 2DG5A 1VFIA 2DYOA 3FWCC 2XW1A 1E7HA 4PO0A 2XVUA 3SIVB 1E78A 3MHHB 4ZBKA 4EMXA 2BX8A 1IJGA 1LOTA 4Z9OA 3W1SA 4HGMB 2K0NA 4GDLB
chains in the Genus database with same CATH topology

4NAWB 2VUEA 4ZCGA 3A73A 2XVVA 2BXHA 1HK4A 4BKEA 1MA9A 4LB9A 3NVIA 4C31B 2BXLA 2V36A 3V09A 4N3ZA 4G01A 2BXPA 5IJEA 4L9QA 1HK1A 2XSIA 3A75A 4IW1A 4M70B 3H3AA 2NQOA 5DBYA 1BKEA 4OR0A 4HGKA 1J78A 3H37A 3KIKA 4LA0A 2Z8JA 2AJEA 5HOZA 3WHSA 3WHRA 2I2ZA 1N5UA 2I30A 2BXBA 4FJCB 4FK5B 5IFOA 3WHQA 2VUFA 2KBZA 2BXEA 2BXMA 4E99A 1TXUA 5IIUA 3V08A 4GG2A 2QHBA 3NVKA 4LB2A 4F5SA 1AO6A 2BXQA 1MIYA 3LU7A 4ZBQA 2LOQA 2XVQA 4N0UD 2DBXA 4F5UA 1E7IA 3CX9A 2BXKA 1TF0A 1E7EA 3FWBC 2BXCA 2CKXA 3GQUA 5GHKA 2BXOA 1E7CA 1GNIA 3NVMA 4F5VA 5IJFA 1E7BA 1HA2A 3M99C 1KXPD 5IJ5A 3TDLA 4LUFA 2JUHA 4TQ1A 4S1YA 3MHSB 4TQ0A 5GIOA 2DBUA 2VDBA 4G04A 3G9KD 1H5WA 5BPKA 4OTUA 2Z8KA 2QMCA 5DQFA 4G03A 3PLAA 2Z8IA 2E0XA 4L9KA 4BY9C 2BXDA 1HK3A 2BXNA 3JRYA 5ID7A 2OZBB 1MIWA 5GIPA 1FOUA 2EFDA 2BXIA 2EFEA 2EFHA 4K71A 2BXAA 3UIVA 1HK2A 2NNWA 4N0FD 1LNSA 1MIVA 1JNBA 3FNMA 3VQIA 1NT2B 3SIUB 1E7GA 2DBWA 4OTTA 5GINA 4FIPB 1O9XA 4DHXB 2YDFA 4F5TA 2XW0A 5FUOA 2OT3A 2ROHA 5ID9A 2BXGA 1H9ZA 1VZSA 3LU8A 4ZUXV 5D7GA 3LU6A 1E7AA 2E0YA 4GDKB 2BXFA 4IW2A 3JQZA 4JK4A 3V03A 4MBEC 4WA6B 1E7FA 3GA9L 3GQXA 1UORA 3ICXA 4ZC6A 3B9MA 5IIHA 3NMUA 4LUHA 2XVWA 2DYMA 1KW2A 4ZBRA 5IIXA 1BM0A 5B5TA 3KJLA 4GDXA 2XMOA 1J7EA 4L8UA 2EFCA 1BJ5A 1HK5A 2QM6A 4J2VA 3B9LA 4K2CA 3SQJA 1GNJA 4OT2A 4Z69A 4W4UB 2DG5A 1VFIA 2DYOA 3FWCC 2XW1A 1E7HA 4PO0A 2XVUA 3SIVB 1E78A 3MHHB 4ZBKA 4EMXA 2BX8A 1IJGA 1LOTA 4Z9OA 3W1SA 4HGMB 4GDLB
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2VUE A;  3A73 A;  2BXH A;  1HK4 A;  4BKE A;  1MA9 A;  4LB9 A;  2BXL A;  3V09 A;  2BXP A;  5IJE A;  4L9Q A;  1HK1 A;  2XSI A;  4IW1 A;  5DBY A;  1BKE A;  4OR0 A;  4HGK A;  1J78 A;  4LA0 A;  5HOZ A;  2I2Z A;  1N5U A;  2I30 A;  2BXB A;  5IFO A;  5IIU A;  2VUF A;  2BXE A;  2BXM A;  4E99 A;  3V08 A;  4LB2 A;  4F5S A;  1AO6 A;  2BXQ A;  3LU7 A;  4ZBQ A;  2XVQ A;  4N0U D;  4F5U A;  1E7I A;  3CX9 A;  2BXK A;  1TF0 A;  1E7E A;  2BXC A;  5GHK A;  2BXO A;  1E7C A;  1GNI A;  4F5V A;  5IJF A;  1E7B A;  1HA2 A;  1KXP D;  5IJ5 A;  3TDL A;  4LUF A;  4S1Y A;  2VDB A;  4G04 A;  5DQF A;  4G03 A;  4L9K A;  2BXD A;  1HK3 A;  2BXN A;  3JRY A;  5ID7 A;  2BXI A;  4K71 A;  2BXA A;  3UIV A;  1HK2 A;  4N0F D;  1LOT A;  1E7G A;  1O9X A;  2YDF A;  4F5T A;  2XW0 A;  5FUO A;  5ID9 A;  2BXG A;  1H9Z A;  3LU8 A;  3LU6 A;  1E7A A;  2BXF A;  4IW2 A;  3JQZ A;  4JK4 A;  3V03 A;  1E7F A;  5IIH A;  1UOR A;  3B9M A;  4LUH A;  2XVW A;  1KW2 A;  4ZBR A;  5IIX A;  1BM0 A;  4L8U A;  1J7E A;  1BJ5 A;  1HK5 A;  4J2V A;  3B9L A;  4K2C A;  3SQJ A;  1GNJ A;  4OT2 A;  4Z69 A;  2XW1 A;  1E7H A;  4PO0 A;  2XVU A;  1E78 A;  4EMX A;  2BX8 A;  2XVV A;  4HGM B; 
#chains in the Genus database with same CATH topology
 2LQH A;  4NAW B;  4DM0 A;  2VUE A;  4ZCG A;  3A73 A;  2XVV A;  2BXH A;  1HK4 A;  4BKE A;  1MA9 A;  4LB9 A;  3NVI A;  4C31 B;  2BXL A;  2V36 A;  2GUT A;  3V09 A;  4N3Z A;  4G01 A;  2BXP A;  5IJE A;  4L9Q A;  1HK1 A;  2XSI A;  3A75 A;  4IW1 A;  4M70 B;  3H3A A;  2NQO A;  5DBY A;  1BKE A;  4OR0 A;  4HGK A;  1J78 A;  3H37 A;  3KIK A;  4LA0 A;  2Z8J A;  2AJE A;  5HOZ A;  3WHS A;  3WHR A;  2I2Z A;  1N5U A;  2I30 A;  2BXB A;  4FJC B;  4FK5 B;  5IFO A;  3WHQ A;  2VUF A;  2KBZ A;  2BXE A;  2BXM A;  4E99 A;  1TXU A;  5IIU A;  3V08 A;  4GG2 A;  3BPJ A;  2QHB A;  3NVK A;  4LB2 A;  4F5S A;  1AO6 A;  2BXQ A;  1MIY A;  3LU7 A;  4ZBQ A;  2LOQ A;  2XVQ A;  4N0U D;  2KWF A;  2DBX A;  4F5U A;  1E7I A;  2AGH B;  2BXK A;  1TF0 A;  1E7E A;  3CX9 A;  1KDX A;  3FWB C;  2BXC A;  2CKX A;  3GQU A;  5GHK A;  2BXO A;  1E7C A;  1GNI A;  3NVM A;  4F5V A;  5IJF A;  1E7B A;  1HA2 A;  1MUS A;  3M99 C;  1KXP D;  5IJ5 A;  2LQI A;  3TDL A;  4LUF A;  2JUH A;  4TQ1 A;  4S1Y A;  3MHS B;  4TQ0 A;  5GIO A;  2DBU A;  2VDB A;  4G04 A;  3G9K D;  1H5W A;  5BPK A;  4OTU A;  2Z8K A;  2QMC A;  5DQF A;  4G03 A;  3PLA A;  2Z8I A;  3ECP A;  2E0X A;  4L9K A;  4BY9 C;  2BXD A;  1HK3 A;  2BXN A;  3JRY A;  5ID7 A;  2OZB B;  1MIW A;  5GIP A;  1FOU A;  2EFD A;  2BXI A;  2EFE A;  2EFH A;  4K71 A;  2BXA A;  3UIV A;  1HK2 A;  1SB0 A;  2NNW A;  4N0F D;  1LNS A;  1MIV A;  1JNB A;  3FNM A;  3VQI A;  1NT2 B;  3SIU B;  1E7G A;  2DBW A;  4OTT A;  5GIN A;  4FIP B;  1O9X A;  4D7X A;  2YDF A;  4DHX B;  4F5T A;  2XW0 A;  5FUO A;  2OT3 A;  2ROH A;  4I9O A;  5ID9 A;  2BXG A;  1MM8 A;  1H9Z A;  1VZS A;  2LXS A;  3LU8 A;  4ZUX V;  5D7G A;  3LU6 A;  1E7A A;  2E0Y A;  4GDK B;  2BXF A;  4IW2 A;  3JQZ A;  4JK4 A;  3V03 A;  4MBE C;  4WA6 B;  1E7F A;  3GA9 L;  3GQX A;  1UOR A;  3ICX A;  4ZC6 A;  3B9M A;  5IIH A;  3NMU A;  4LUH A;  2XVW A;  2DYM A;  1KW2 A;  4ZBR A;  2LXT A;  5IIX A;  1BM0 A;  5B5T A;  3KJL A;  4GDX A;  2XMO A;  1J7E A;  4L8U A;  2EFC A;  1BJ5 A;  1HK5 A;  2QM6 A;  4J2V A;  3B9L A;  1MUH A;  4K2C A;  3SQJ A;  1GNJ A;  4OT2 A;  4Z69 A;  4W4U B;  2DG5 A;  1VFI A;  2DYO A;  3FWC C;  2XW1 A;  1E7H A;  4PO0 A;  2XVU A;  3SIV B;  1E78 A;  3MHH B;  4ZBK A;  4EMX A;  2BX8 A;  1IJG A;  1LOT A;  4Z9O A;  3W1S A;  4HGM B;  2K0N A;  4GDL B; 
#chains in the Genus database with same CATH homology
 4NAW B;  2VUE A;  4ZCG A;  3A73 A;  2XVV A;  2BXH A;  1HK4 A;  4BKE A;  1MA9 A;  4LB9 A;  3NVI A;  4C31 B;  2BXL A;  2V36 A;  3V09 A;  4N3Z A;  4G01 A;  2BXP A;  5IJE A;  4L9Q A;  1HK1 A;  2XSI A;  3A75 A;  4IW1 A;  4M70 B;  3H3A A;  2NQO A;  5DBY A;  1BKE A;  4OR0 A;  4HGK A;  1J78 A;  3H37 A;  3KIK A;  4LA0 A;  2Z8J A;  2AJE A;  5HOZ A;  3WHS A;  3WHR A;  2I2Z A;  1N5U A;  2I30 A;  2BXB A;  4FJC B;  4FK5 B;  5IFO A;  3WHQ A;  2VUF A;  2KBZ A;  2BXE A;  2BXM A;  4E99 A;  1TXU A;  5IIU A;  3V08 A;  4GG2 A;  2QHB A;  3NVK A;  4LB2 A;  4F5S A;  1AO6 A;  2BXQ A;  1MIY A;  3LU7 A;  4ZBQ A;  2LOQ A;  2XVQ A;  4N0U D;  2DBX A;  4F5U A;  1E7I A;  3CX9 A;  2BXK A;  1TF0 A;  1E7E A;  3FWB C;  2BXC A;  2CKX A;  3GQU A;  5GHK A;  2BXO A;  1E7C A;  1GNI A;  3NVM A;  4F5V A;  5IJF A;  1E7B A;  1HA2 A;  3M99 C;  1KXP D;  5IJ5 A;  3TDL A;  4LUF A;  2JUH A;  4TQ1 A;  4S1Y A;  3MHS B;  4TQ0 A;  5GIO A;  2DBU A;  2VDB A;  4G04 A;  3G9K D;  1H5W A;  5BPK A;  4OTU A;  2Z8K A;  2QMC A;  5DQF A;  4G03 A;  3PLA A;  2Z8I A;  2E0X A;  4L9K A;  4BY9 C;  2BXD A;  1HK3 A;  2BXN A;  3JRY A;  5ID7 A;  2OZB B;  1MIW A;  5GIP A;  1FOU A;  2EFD A;  2BXI A;  2EFE A;  2EFH A;  4K71 A;  2BXA A;  3UIV A;  1HK2 A;  2NNW A;  4N0F D;  1LNS A;  1MIV A;  1JNB A;  3FNM A;  3VQI A;  1NT2 B;  3SIU B;  1E7G A;  2DBW A;  4OTT A;  5GIN A;  4FIP B;  1O9X A;  4DHX B;  2YDF A;  4F5T A;  2XW0 A;  5FUO A;  2OT3 A;  2ROH A;  5ID9 A;  2BXG A;  1H9Z A;  1VZS A;  3LU8 A;  4ZUX V;  5D7G A;  3LU6 A;  1E7A A;  2E0Y A;  4GDK B;  2BXF A;  4IW2 A;  3JQZ A;  4JK4 A;  3V03 A;  4MBE C;  4WA6 B;  1E7F A;  3GA9 L;  3GQX A;  1UOR A;  3ICX A;  4ZC6 A;  3B9M A;  5IIH A;  3NMU A;  4LUH A;  2XVW A;  2DYM A;  1KW2 A;  4ZBR A;  5IIX A;  1BM0 A;  5B5T A;  3KJL A;  4GDX A;  2XMO A;  1J7E A;  4L8U A;  2EFC A;  1BJ5 A;  1HK5 A;  2QM6 A;  4J2V A;  3B9L A;  4K2C A;  3SQJ A;  1GNJ A;  4OT2 A;  4Z69 A;  4W4U B;  2DG5 A;  1VFI A;  2DYO A;  3FWC C;  2XW1 A;  1E7H A;  4PO0 A;  2XVU A;  3SIV B;  1E78 A;  3MHH B;  4ZBK A;  4EMX A;  2BX8 A;  1IJG A;  1LOT A;  4Z9O A;  3W1S A;  4HGM B;  4GDL B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4HGKA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations