4HGM | Genus

Total Genus 173

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	173
sequence length	489
structure length	478
Chain Sequence	KSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVAEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCSLVNRRPCFSALE

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Immune system
source organism	Squalus acanthias
publication title	Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis. pubmed doi rcsb
molecule keywords	Shark V-NAR
total genus	173
structure length	478
sequence length	489
ec nomenclature
pdb deposition date	2012-10-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4hgmB02

2VUEA 2BXKA 2BXGA 4OR0A 4Z69A 1GNJA 4JK4A 2VUFA 2XSIA 4G03A 1MA9A 3JRYA 2BXMA 2BXQA 4IW1A 4F5UA 1E7AA 4HGMB 3LU6A 4L9KA 1E78A 4E99A 2I30A 3B9MA 2XVQA 5HOZA 1E7BA 4EMXA 2BXOA 4ZBQA 1E7FA 4BKEA 4F5SA 5IIXA 2BXHA 1HA2A 1UORA 3LU8A 3SQJA 4LB9A 5IIUA 2BXBA 5ID9A 1E7IA 4K71A 2BXNA 4L8UA 1BM0A 2I2ZA 2XVWA 4ZBRA 3CX9A 3V08A 4N0FD 1J7EA 4L9QA 5IJFA 4N0UD 4HGKA 4OT2A 5GHKA 5DBYA 2XVUA 2BXPA 1E7EA 3A73A 1HK3A 1GNIA 3B9LA 1J78A 1HK5A 5IJEA 1BKEA 1H9ZA 1TF0A 2BXCA 4F5VA 2BXEA 2BXIA 2BXAA 2XW1A 4LA0A 4IW2A 2XW0A 3JQZA 5IJ5A 4LB2A 1KXPD 1E7HA 2BXLA 4PO0A 1LOTA 1HK2A 1KW2A 2BX8A 4F5TA 5ID7A 1E7GA 5IFOA 4LUHA 1HK4A 4LUFA 2VDBA 3TDLA 1E7CA 2BXFA 1HK1A 2XVVA 4G04A 2YDFA 1AO6A 1O9XA 5IIHA 5FUOA 3V09A 3LU7A 4K2CA 4S1YA 5DQFA 1N5UA 3UIVA 3V03A 2BXDA 4J2VA 1BJ5A
chains in the Genus database with same CATH superfamily

3WHSA 2VUEA 2BXKA 2BXGA 4OR0A 4Z69A 1GNJA 4JK4A 1LNSA 2V36A 2VUFA 1MIWA 2XSIA 4G03A 1VZSA 1MA9A 3JRYA 5GINA 2BXMA 2BXQA 4G01A 3ECPA 4IW1A 4F5UA 2Z8KA 1E7AA 4I9OA 3WHQA 3WHRA 4HGMB 2E0YA 2KWFA 3LU6A 4L9KA 2NNWA 2KBZA 3ICXA 3H37A 1E78A 4E99A 4TQ0A 2DBUA 2I30A 4MBEC 3B9MA 3W1SA 4OTUA 2XVQA 5HOZA 1E7BA 4M70B 4EMXA 2BXOA 4ZBQA 1E7FA 4BKEA 4F5SA 5IIXA 2BXHA 3A75A 1HA2A 1UORA 3FWCC 3BPJA 3LU8A 2OT3A 4GDXA 3KIKA 4LB9A 3SQJA 5IIUA 2BXBA 3H3AA 1IJGA 2AGHB 2EFEA 1E7IA 3FWBC 4K71A 5ID9A 2BXNA 4L8UA 5GIPA 1BM0A 3MHHB 2I2ZA 2Z8JA 2XVWA 2K0NA 3CX9A 1TXUA 4ZC6A 4ZBRA 3V08A 2OZBB 4N0FD 1J7EA 4ZBKA 4L9QA 5IJFA 2QHBA 4FK5B 4N3ZA 4N0UD 1MUHA 2EFHA 4HGKA 4OT2A 5GHKA 5DBYA 2XVUA 2JUHA 2DG5A 2EFDA 4C31B 2BXPA 1E7EA 2XMOA 2CKXA 3A73A 5D7GA 4DHXB 3GQXA 2GUTA 1HK3A 1GNIA 3B9LA 3NVKA 2NQOA 3G9KD 1J78A 1HK5A 2LQIA 4GDKB 3VQIA 5IJEA 1MIVA 5GIOA 4OTTA 2QMCA 1FOUA 1BKEA 2LOQA 1H9ZA 4FIPB 1KDXA 1TF0A 2BXCA 2LQHA 4F5VA 1MUSA 2BXEA 3SIVB 2BXIA 2BXAA 1VFIA 2XW1A 4LA0A 3MHSB 4IW2A 4D7XA 2E0XA 2DYMA 3KJLA 2XW0A 3JQZA 3SIUB 4ZCGA 2Z8IA 4LB2A 4TQ1A 5IJ5A 1KXPD 3FNMA 2LXSA 1E7HA 2BXLA 2AJEA 4FJCB 4Z9OA 5B5TA 4PO0A 1LOTA 1HK2A 1KW2A 2BX8A 4W4UB 4ZUXV 4F5TA 1NT2B 5ID7A 1E7GA 5IFOA 4LUHA 2DBXA 4GG2A 3NVIA 2LXTA 2DYOA 1HK4A 5BPKA 4NAWB 4LUFA 1MM8A 2DBWA 2VDBA 4DM0A 1JNBA 3TDLA 3GA9L 1E7CA 2BXFA 1HK1A 2XVVA 2ROHA 2EFCA 4G04A 2YDFA 1AO6A 1O9XA 3M99C 5IIHA 5FUOA 4GDLB 4BY9C 3PLAA 3V09A 3LU7A 4K2CA 4S1YA 3GQUA 5DQFA 1N5UA 2QM6A 3NMUA 3UIVA 3V03A 2BXDA 4WA6B 1SB0A 3NVMA 1H5WA 1MIYA 4J2VA 1BJ5A
chains in the Genus database with same CATH topology

3WHSA 2VUEA 2BXKA 2BXGA 4OR0A 4Z69A 1GNJA 4JK4A 1LNSA 2V36A 2VUFA 1MIWA 2XSIA 4G03A 1VZSA 1MA9A 3JRYA 5GINA 2BXMA 2BXQA 4G01A 4IW1A 4F5UA 2Z8KA 1E7AA 3WHQA 3WHRA 4HGMB 2E0YA 3LU6A 4L9KA 2NNWA 2KBZA 3ICXA 3H37A 1E78A 4E99A 4TQ0A 2DBUA 2I30A 4MBEC 3B9MA 3W1SA 4OTUA 2XVQA 5HOZA 1E7BA 4M70B 4EMXA 2BXOA 4ZBQA 1E7FA 4BKEA 4F5SA 5IIXA 2BXHA 3A75A 1HA2A 1UORA 3FWCC 3LU8A 2OT3A 4GDXA 3KIKA 4LB9A 3SQJA 5IIUA 2BXBA 3H3AA 1IJGA 2EFEA 3FWBC 1E7IA 4K71A 5ID9A 2BXNA 4L8UA 5GIPA 1BM0A 3MHHB 2I2ZA 2Z8JA 2XVWA 4ZBRA 3CX9A 1TXUA 4ZC6A 3V08A 2OZBB 4N0FD 1J7EA 4ZBKA 4L9QA 5IJFA 2QHBA 4FK5B 4N3ZA 4N0UD 2EFHA 4HGKA 4OT2A 5GHKA 5DBYA 2XVUA 2JUHA 2DG5A 2EFDA 4C31B 2BXPA 1E7EA 2XMOA 2CKXA 3A73A 5D7GA 4DHXB 3GQXA 3NVKA 1HK3A 1GNIA 3B9LA 2NQOA 3G9KD 1J78A 1HK5A 3VQIA 4GDKB 5IJEA 1MIVA 5GIOA 4OTTA 2QMCA 1FOUA 1BKEA 2LOQA 1H9ZA 4FIPB 1TF0A 2BXCA 4F5VA 2BXEA 3SIVB 2BXIA 2BXAA 1VFIA 2XW1A 4LA0A 3MHSB 4IW2A 2E0XA 2DYMA 3KJLA 2XW0A 3JQZA 3SIUB 4ZCGA 2Z8IA 4LB2A 4TQ1A 5IJ5A 1KXPD 3FNMA 4FJCB 1E7HA 2BXLA 2AJEA 4Z9OA 5B5TA 4PO0A 1LOTA 1HK2A 1KW2A 2BX8A 4W4UB 4ZUXV 4F5TA 1NT2B 5ID7A 1E7GA 5IFOA 4LUHA 2DBXA 4GG2A 3NVIA 2DYOA 1HK4A 5BPKA 4NAWB 4LUFA 2DBWA 2VDBA 1JNBA 3TDLA 3GA9L 1E7CA 2BXFA 1HK1A 2XVVA 2ROHA 2EFCA 4G04A 2YDFA 1AO6A 1O9XA 3M99C 5IIHA 5FUOA 4GDLB 4BY9C 3PLAA 3V09A 3LU7A 4K2CA 4S1YA 3GQUA 5DQFA 1N5UA 2QM6A 3NMUA 3UIVA 3V03A 2BXDA 4WA6B 3NVMA 1H5WA 1MIYA 4J2VA 1BJ5A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2VUE A;  2BXK A;  2BXG A;  4OR0 A;  4Z69 A;  1GNJ A;  4JK4 A;  2VUF A;  2XSI A;  4G03 A;  1MA9 A;  3JRY A;  2BXM A;  2BXQ A;  4IW1 A;  4F5U A;  1E7A A;  4HGM B;  3LU6 A;  4L9K A;  1E78 A;  4E99 A;  2I30 A;  3B9M A;  2XVQ A;  5HOZ A;  1E7B A;  4EMX A;  2BXO A;  4ZBQ A;  1E7F A;  4BKE A;  4F5S A;  5IIX A;  2BXH A;  1HA2 A;  1UOR A;  3LU8 A;  3SQJ A;  4LB9 A;  5IIU A;  2BXB A;  5ID9 A;  1E7I A;  4K71 A;  2BXN A;  4L8U A;  1BM0 A;  2I2Z A;  2XVW A;  4ZBR A;  3CX9 A;  3V08 A;  4N0F D;  1J7E A;  4L9Q A;  5IJF A;  4N0U D;  4HGK A;  4OT2 A;  5GHK A;  5DBY A;  2XVU A;  2BXP A;  1E7E A;  3A73 A;  1HK3 A;  1GNI A;  3B9L A;  1J78 A;  1HK5 A;  5IJE A;  1BKE A;  1H9Z A;  1TF0 A;  2BXC A;  4F5V A;  2BXE A;  2BXI A;  2BXA A;  2XW1 A;  4LA0 A;  4IW2 A;  2XW0 A;  3JQZ A;  5IJ5 A;  4LB2 A;  1KXP D;  1E7H A;  2BXL A;  4PO0 A;  1LOT A;  1HK2 A;  1KW2 A;  2BX8 A;  4F5T A;  5ID7 A;  1E7G A;  5IFO A;  4LUH A;  1HK4 A;  4LUF A;  2VDB A;  3TDL A;  1E7C A;  2BXF A;  1HK1 A;  2XVV A;  4G04 A;  2YDF A;  1AO6 A;  1O9X A;  5IIH A;  5FUO A;  3V09 A;  3LU7 A;  4K2C A;  4S1Y A;  5DQF A;  1N5U A;  3UIV A;  3V03 A;  2BXD A;  4J2V A;  1BJ5 A; 
#chains in the Genus database with same CATH topology
 3WHS A;  2VUE A;  2BXK A;  2BXG A;  4OR0 A;  4Z69 A;  1GNJ A;  4JK4 A;  1LNS A;  2V36 A;  2VUF A;  1MIW A;  2XSI A;  4G03 A;  1VZS A;  1MA9 A;  3JRY A;  5GIN A;  2BXM A;  2BXQ A;  4G01 A;  3ECP A;  4IW1 A;  4F5U A;  2Z8K A;  1E7A A;  4I9O A;  3WHQ A;  3WHR A;  4HGM B;  2E0Y A;  2KWF A;  3LU6 A;  4L9K A;  2NNW A;  2KBZ A;  3ICX A;  3H37 A;  1E78 A;  4E99 A;  4TQ0 A;  2DBU A;  2I30 A;  4MBE C;  3B9M A;  3W1S A;  4OTU A;  2XVQ A;  5HOZ A;  1E7B A;  4M70 B;  4EMX A;  2BXO A;  4ZBQ A;  1E7F A;  4BKE A;  4F5S A;  5IIX A;  2BXH A;  3A75 A;  1HA2 A;  1UOR A;  3FWC C;  3BPJ A;  3LU8 A;  2OT3 A;  4GDX A;  3KIK A;  4LB9 A;  3SQJ A;  5IIU A;  2BXB A;  3H3A A;  1IJG A;  2AGH B;  2EFE A;  1E7I A;  3FWB C;  4K71 A;  5ID9 A;  2BXN A;  4L8U A;  5GIP A;  1BM0 A;  3MHH B;  2I2Z A;  2Z8J A;  2XVW A;  2K0N A;  3CX9 A;  1TXU A;  4ZC6 A;  4ZBR A;  3V08 A;  2OZB B;  4N0F D;  1J7E A;  4ZBK A;  4L9Q A;  5IJF A;  2QHB A;  4FK5 B;  4N3Z A;  4N0U D;  1MUH A;  2EFH A;  4HGK A;  4OT2 A;  5GHK A;  5DBY A;  2XVU A;  2JUH A;  2DG5 A;  2EFD A;  4C31 B;  2BXP A;  1E7E A;  2XMO A;  2CKX A;  3A73 A;  5D7G A;  4DHX B;  3GQX A;  2GUT A;  1HK3 A;  1GNI A;  3B9L A;  3NVK A;  2NQO A;  3G9K D;  1J78 A;  1HK5 A;  2LQI A;  4GDK B;  3VQI A;  5IJE A;  1MIV A;  5GIO A;  4OTT A;  2QMC A;  1FOU A;  1BKE A;  2LOQ A;  1H9Z A;  4FIP B;  1KDX A;  1TF0 A;  2BXC A;  2LQH A;  4F5V A;  1MUS A;  2BXE A;  3SIV B;  2BXI A;  2BXA A;  1VFI A;  2XW1 A;  4LA0 A;  3MHS B;  4IW2 A;  4D7X A;  2E0X A;  2DYM A;  3KJL A;  2XW0 A;  3JQZ A;  3SIU B;  4ZCG A;  2Z8I A;  4LB2 A;  4TQ1 A;  5IJ5 A;  1KXP D;  3FNM A;  2LXS A;  1E7H A;  2BXL A;  2AJE A;  4FJC B;  4Z9O A;  5B5T A;  4PO0 A;  1LOT A;  1HK2 A;  1KW2 A;  2BX8 A;  4W4U B;  4ZUX V;  4F5T A;  1NT2 B;  5ID7 A;  1E7G A;  5IFO A;  4LUH A;  2DBX A;  4GG2 A;  3NVI A;  2LXT A;  2DYO A;  1HK4 A;  5BPK A;  4NAW B;  4LUF A;  1MM8 A;  2DBW A;  2VDB A;  4DM0 A;  1JNB A;  3TDL A;  3GA9 L;  1E7C A;  2BXF A;  1HK1 A;  2XVV A;  2ROH A;  2EFC A;  4G04 A;  2YDF A;  1AO6 A;  1O9X A;  3M99 C;  5IIH A;  5FUO A;  4GDL B;  4BY9 C;  3PLA A;  3V09 A;  3LU7 A;  4K2C A;  4S1Y A;  3GQU A;  5DQF A;  1N5U A;  2QM6 A;  3NMU A;  3UIV A;  3V03 A;  2BXD A;  4WA6 B;  1SB0 A;  3NVM A;  1H5W A;  1MIY A;  4J2V A;  1BJ5 A; 
#chains in the Genus database with same CATH homology
 3WHS A;  2VUE A;  2BXK A;  2BXG A;  4OR0 A;  4Z69 A;  1GNJ A;  4JK4 A;  1LNS A;  2V36 A;  2VUF A;  1MIW A;  2XSI A;  4G03 A;  1VZS A;  1MA9 A;  3JRY A;  5GIN A;  2BXM A;  2BXQ A;  4G01 A;  4IW1 A;  4F5U A;  2Z8K A;  1E7A A;  3WHQ A;  3WHR A;  4HGM B;  2E0Y A;  3LU6 A;  4L9K A;  2NNW A;  2KBZ A;  3ICX A;  3H37 A;  1E78 A;  4E99 A;  4TQ0 A;  2DBU A;  2I30 A;  4MBE C;  3B9M A;  3W1S A;  4OTU A;  2XVQ A;  5HOZ A;  1E7B A;  4M70 B;  4EMX A;  2BXO A;  4ZBQ A;  1E7F A;  4BKE A;  4F5S A;  5IIX A;  2BXH A;  3A75 A;  1HA2 A;  1UOR A;  3FWC C;  3LU8 A;  2OT3 A;  4GDX A;  3KIK A;  4LB9 A;  3SQJ A;  5IIU A;  2BXB A;  3H3A A;  1IJG A;  2EFE A;  3FWB C;  1E7I A;  4K71 A;  5ID9 A;  2BXN A;  4L8U A;  5GIP A;  1BM0 A;  3MHH B;  2I2Z A;  2Z8J A;  2XVW A;  4ZBR A;  3CX9 A;  1TXU A;  4ZC6 A;  3V08 A;  2OZB B;  4N0F D;  1J7E A;  4ZBK A;  4L9Q A;  5IJF A;  2QHB A;  4FK5 B;  4N3Z A;  4N0U D;  2EFH A;  4HGK A;  4OT2 A;  5GHK A;  5DBY A;  2XVU A;  2JUH A;  2DG5 A;  2EFD A;  4C31 B;  2BXP A;  1E7E A;  2XMO A;  2CKX A;  3A73 A;  5D7G A;  4DHX B;  3GQX A;  3NVK A;  1HK3 A;  1GNI A;  3B9L A;  2NQO A;  3G9K D;  1J78 A;  1HK5 A;  3VQI A;  4GDK B;  5IJE A;  1MIV A;  5GIO A;  4OTT A;  2QMC A;  1FOU A;  1BKE A;  2LOQ A;  1H9Z A;  4FIP B;  1TF0 A;  2BXC A;  4F5V A;  2BXE A;  3SIV B;  2BXI A;  2BXA A;  1VFI A;  2XW1 A;  4LA0 A;  3MHS B;  4IW2 A;  2E0X A;  2DYM A;  3KJL A;  2XW0 A;  3JQZ A;  3SIU B;  4ZCG A;  2Z8I A;  4LB2 A;  4TQ1 A;  5IJ5 A;  1KXP D;  3FNM A;  4FJC B;  1E7H A;  2BXL A;  2AJE A;  4Z9O A;  5B5T A;  4PO0 A;  1LOT A;  1HK2 A;  1KW2 A;  2BX8 A;  4W4U B;  4ZUX V;  4F5T A;  1NT2 B;  5ID7 A;  1E7G A;  5IFO A;  4LUH A;  2DBX A;  4GG2 A;  3NVI A;  2DYO A;  1HK4 A;  5BPK A;  4NAW B;  4LUF A;  2DBW A;  2VDB A;  1JNB A;  3TDL A;  3GA9 L;  1E7C A;  2BXF A;  1HK1 A;  2XVV A;  2ROH A;  2EFC A;  4G04 A;  2YDF A;  1AO6 A;  1O9X A;  3M99 C;  5IIH A;  5FUO A;  4GDL B;  4BY9 C;  3PLA A;  3V09 A;  3LU7 A;  4K2C A;  4S1Y A;  3GQU A;  5DQF A;  1N5U A;  2QM6 A;  3NMU A;  3UIV A;  3V03 A;  2BXD A;  4WA6 B;  3NVM A;  1H5W A;  1MIY A;  4J2V A;  1BJ5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4HGMB

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations