4IW1 | Genus

Total Genus 202

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	202
sequence length	572
structure length	560
Chain Sequence	SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTDCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLV

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transport protein
source organism	Homo sapiens
publication title	Structural mechanism of ring-opening reaction of glucose by human serum albumin pubmed doi rcsb
molecule keywords	Serum albumin
total genus	202
structure length	560
sequence length	572
ec nomenclature
pdb deposition date	2013-01-23

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4iw1A03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4iw1A02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4iw1A04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4iw1A01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4iw1A06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4iw1A05

5FUOA 4J2VA 4L9KA 3CX9A 2BXIA 2XVVA 1KW2A 2BXCA 4HGMB 1HK1A 3A73A 4L8UA 1HK3A 5ID9A 2VUEA 2BXMA 5IJEA 2XVWA 4G03A 3V03A 1H9ZA 4ZBQA 1E7CA 1MA9A 4ZBRA 5IIXA 2BXAA 1BKEA 2I2ZA 4LUHA 4IW2A 4K2CA 4LB9A 1E7IA 1E7FA 4F5SA 4Z69A 1O9XA 3JQZA 1BJ5A 4G04A 3LU7A 5GHKA 5IIUA 1E78A 4JK4A 2XSIA 2VDBA 2BXNA 3V09A 1HA2A 5IFOA 3B9MA 4OT2A 3LU8A 1KXPD 4E99A 4F5TA 1E7BA 3LU6A 1J7EA 2XVUA 2YDFA 1HK5A 1UORA 1AO6A 1E7HA 2BX8A 4K71A 5DQFA 4L9QA 4LUFA 2BXEA 5HOZA 3V08A 2BXPA 2BXOA 3SQJA 2XW1A 3B9LA 4F5UA 1E7AA 2BXFA 4BKEA 5IJFA 5IJ5A 4HGKA 1J78A 4N0FD 2BXKA 3TDLA 2BXHA 2XW0A 4IW1A 4EMXA 4PO0A 2I30A 4LB2A 1BM0A 5ID7A 3UIVA 2BXLA 1E7GA 5IIHA 4S1YA 2BXGA 2BXQA 4LA0A 5DBYA 2BXBA 1GNIA 1N5UA 1TF0A 2VUFA 1E7EA 3JRYA 1LOTA 1HK4A 2XVQA 1HK2A 2BXDA 4N0UD 4F5VA 4OR0A 1GNJA
chains in the Genus database with same CATH superfamily

5FUOA 4MBEC 1MIYA 3MHHB 4J2VA 4L9KA 4TQ0A 3KJLA 2E0YA 3M99C 3CX9A 2BXIA 2XVVA 1KW2A 2NQOA 2BXCA 4HGMB 1HK1A 3A73A 4L8UA 4DM0A 3MHSB 1MUHA 1HK3A 5ID9A 2VUEA 2BXMA 4GG2A 2EFCA 1TXUA 5IJEA 3SIUB 2XVWA 3WHRA 4G03A 3V03A 2QM6A 4ZBKA 1H9ZA 2V36A 4ZBQA 1E7CA 1MA9A 4ZBRA 5IIXA 3VQIA 1KDXA 2BXAA 1BKEA 2I2ZA 4TQ1A 4GDXA 4LUHA 4IW2A 4K2CA 4ZUXV 2E0XA 2OT3A 4LB9A 2LQIA 5B5TA 1E7IA 2DG5A 1E7FA 3FWCC 3KIKA 3ICXA 1NT2B 4F5SA 4Z9OA 4G01A 1H5WA 1O9XA 4Z69A 3JQZA 1BJ5A 4G04A 2DBWA 3NVMA 4M70B 3LU7A 3FWBC 5GHKA 5IIUA 1E78A 4ZC6A 4JK4A 2XSIA 2VDBA 2JUHA 2BXNA 3V09A 4DHXB 4WA6B 4GDLB 1HA2A 4OTUA 2OZBB 5IFOA 3B9MA 4OT2A 3LU8A 1KXPD 4FIPB 4C31B 5BPKA 4E99A 4F5TA 3ECPA 3NVKA 4GDKB 2AJEA 1E7BA 1IJGA 3LU6A 1J7EA 2XVUA 5GINA 2YDFA 1HK5A 1UORA 1AO6A 1E7HA 2DYOA 3BPJA 2BX8A 4K71A 4W4UB 5DQFA 5GIPA 1LNSA 1MM8A 1MUSA 4I9OA 2LXSA 3A75A 4L9QA 4LUFA 2BXEA 2EFHA 1FOUA 2Z8KA 5HOZA 3V08A 2BXPA 2BXOA 3H3AA 3SQJA 2XW1A 3PLAA 3B9LA 1VFIA 4F5UA 4BY9C 1MIVA 1E7AA 2Z8IA 2Z8JA 3G9KD 2EFEA 2BXFA 4NAWB 4FK5B 1VZSA 4BKEA 5IJFA 5IJ5A 2QHBA 2DBUA 4N3ZA 2LQHA 2QMCA 4HGKA 2KBZA 1J78A 4N0FD 2BXKA 1JNBA 4D7XA 3WHQA 2LOQA 3TDLA 2BXHA 2XW0A 4IW1A 2K0NA 4EMXA 4PO0A 3W1SA 2GUTA 2ROHA 5D7GA 2I30A 4LB2A 2XMOA 3H37A 2CKXA 1BM0A 5ID7A 3FNMA 2LXTA 3UIVA 3GQUA 2AGHB 2BXLA 3NMUA 4OTTA 1E7GA 5IIHA 1SB0A 2DYMA 4FJCB 4S1YA 2BXGA 4ZCGA 2BXQA 4LA0A 5DBYA 2BXBA 1GNIA 1N5UA 2KWFA 1TF0A 2DBXA 1E7EA 2VUFA 3JRYA 3SIVB 3GQXA 1LOTA 3WHSA 1HK4A 2EFDA 1HK2A 2BXDA 2NNWA 2XVQA 4N0UD 3GA9L 4F5VA 4OR0A 5GIOA 1MIWA 1GNJA 3NVIA
chains in the Genus database with same CATH topology

5FUOA 4MBEC 1MIYA 3MHHB 4J2VA 4L9KA 4TQ0A 3KJLA 2E0YA 3M99C 3CX9A 2BXIA 2XVVA 1KW2A 2NQOA 2BXCA 4HGMB 1HK1A 3A73A 4L8UA 3MHSB 1HK3A 5ID9A 2VUEA 2BXMA 4GG2A 2EFCA 1TXUA 5IJEA 3SIUB 2XVWA 3WHRA 4G03A 3V03A 2QM6A 4ZBKA 1H9ZA 2V36A 4ZBQA 1E7CA 1MA9A 4ZBRA 5IIXA 3VQIA 2BXAA 1BKEA 2I2ZA 4TQ1A 4GDXA 4LUHA 4IW2A 4K2CA 4ZUXV 2E0XA 2OT3A 4LB9A 5B5TA 1E7IA 2DG5A 1E7FA 3FWCC 3KIKA 3ICXA 1NT2B 4F5SA 4Z9OA 4G01A 1H5WA 1O9XA 4Z69A 3JQZA 1BJ5A 4G04A 2DBWA 3NVMA 4M70B 3LU7A 3FWBC 5GHKA 5IIUA 1E78A 4ZC6A 4JK4A 2XSIA 2VDBA 2JUHA 2BXNA 3V09A 4DHXB 4WA6B 4GDLB 1HA2A 4OTUA 2OZBB 5IFOA 3B9MA 4OT2A 3LU8A 1KXPD 4FIPB 4C31B 5BPKA 4E99A 4F5TA 3NVKA 4GDKB 2AJEA 1E7BA 1IJGA 3LU6A 1J7EA 2XVUA 5GINA 2YDFA 1HK5A 1UORA 1AO6A 1E7HA 2DYOA 5GIPA 2BX8A 4K71A 4W4UB 5DQFA 1LNSA 3A75A 4L9QA 4LUFA 2BXEA 2EFHA 1FOUA 2Z8KA 5HOZA 3V08A 2BXPA 2BXOA 3H3AA 3SQJA 2XW1A 3PLAA 3B9LA 1VFIA 4F5UA 4BY9C 1MIVA 1E7AA 2Z8IA 2Z8JA 3G9KD 2EFEA 2BXFA 4NAWB 4FK5B 1VZSA 4BKEA 5IJFA 5IJ5A 2QHBA 2DBUA 4N3ZA 2QMCA 4HGKA 2KBZA 1J78A 4N0FD 2BXKA 1JNBA 3WHQA 2LOQA 3TDLA 2BXHA 2XW0A 4IW1A 4EMXA 4PO0A 3W1SA 2ROHA 5D7GA 2I30A 4LB2A 2XMOA 3H37A 2CKXA 1BM0A 5ID7A 3FNMA 3UIVA 3GQUA 2BXLA 3NMUA 4OTTA 1E7GA 5IIHA 2DYMA 4FJCB 4S1YA 2BXGA 4ZCGA 2BXQA 4LA0A 5DBYA 2BXBA 1GNIA 1N5UA 1TF0A 2DBXA 1E7EA 2VUFA 3JRYA 3SIVB 3GQXA 1LOTA 3WHSA 1HK4A 2EFDA 1HK2A 2BXDA 2NNWA 2XVQA 4N0UD 3GA9L 4F5VA 4OR0A 5GIOA 1MIWA 1GNJA 3NVIA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 5FUO A;  4J2V A;  4L9K A;  3CX9 A;  2BXI A;  2XVV A;  1KW2 A;  2BXC A;  4HGM B;  1HK1 A;  3A73 A;  4L8U A;  1HK3 A;  5ID9 A;  2VUE A;  2BXM A;  5IJE A;  2XVW A;  4G03 A;  3V03 A;  1H9Z A;  4ZBQ A;  1E7C A;  1MA9 A;  4ZBR A;  5IIX A;  2BXA A;  1BKE A;  2I2Z A;  4LUH A;  4IW2 A;  4K2C A;  4LB9 A;  1E7I A;  1E7F A;  4F5S A;  4Z69 A;  1O9X A;  3JQZ A;  1BJ5 A;  4G04 A;  3LU7 A;  5GHK A;  5IIU A;  1E78 A;  4JK4 A;  2XSI A;  2VDB A;  2BXN A;  3V09 A;  1HA2 A;  5IFO A;  3B9M A;  4OT2 A;  3LU8 A;  1KXP D;  4E99 A;  4F5T A;  1E7B A;  3LU6 A;  1J7E A;  2XVU A;  2YDF A;  1HK5 A;  1UOR A;  1AO6 A;  1E7H A;  2BX8 A;  4K71 A;  5DQF A;  4L9Q A;  4LUF A;  2BXE A;  5HOZ A;  3V08 A;  2BXP A;  2BXO A;  3SQJ A;  2XW1 A;  3B9L A;  4F5U A;  1E7A A;  2BXF A;  4BKE A;  5IJF A;  5IJ5 A;  4HGK A;  1J78 A;  4N0F D;  2BXK A;  3TDL A;  2BXH A;  2XW0 A;  4IW1 A;  4EMX A;  4PO0 A;  2I30 A;  4LB2 A;  1BM0 A;  5ID7 A;  3UIV A;  2BXL A;  1E7G A;  5IIH A;  4S1Y A;  2BXG A;  2BXQ A;  4LA0 A;  5DBY A;  2BXB A;  1GNI A;  1N5U A;  1TF0 A;  2VUF A;  1E7E A;  3JRY A;  1LOT A;  1HK4 A;  2XVQ A;  1HK2 A;  2BXD A;  4N0U D;  4F5V A;  4OR0 A;  1GNJ A; 
#chains in the Genus database with same CATH topology
 5FUO A;  4MBE C;  1MIY A;  3MHH B;  4J2V A;  4L9K A;  4TQ0 A;  3KJL A;  2E0Y A;  3M99 C;  3CX9 A;  2BXI A;  2XVV A;  1KW2 A;  2NQO A;  2BXC A;  4HGM B;  1HK1 A;  3A73 A;  4L8U A;  4DM0 A;  3MHS B;  1MUH A;  1HK3 A;  5ID9 A;  2VUE A;  2BXM A;  4GG2 A;  2EFC A;  1TXU A;  5IJE A;  3SIU B;  2XVW A;  3WHR A;  4G03 A;  3V03 A;  2QM6 A;  4ZBK A;  1H9Z A;  2V36 A;  4ZBQ A;  1E7C A;  1MA9 A;  4ZBR A;  5IIX A;  3VQI A;  1KDX A;  2BXA A;  1BKE A;  2I2Z A;  4TQ1 A;  4GDX A;  4LUH A;  4IW2 A;  4K2C A;  4ZUX V;  2E0X A;  2OT3 A;  4LB9 A;  2LQI A;  5B5T A;  1E7I A;  2DG5 A;  1E7F A;  3FWC C;  3KIK A;  3ICX A;  1NT2 B;  4F5S A;  4Z9O A;  4G01 A;  1H5W A;  1O9X A;  4Z69 A;  3JQZ A;  1BJ5 A;  4G04 A;  2DBW A;  3NVM A;  4M70 B;  3LU7 A;  3FWB C;  5GHK A;  5IIU A;  1E78 A;  4ZC6 A;  4JK4 A;  2XSI A;  2VDB A;  2JUH A;  2BXN A;  3V09 A;  4DHX B;  4WA6 B;  4GDL B;  1HA2 A;  4OTU A;  2OZB B;  5IFO A;  3B9M A;  4OT2 A;  3LU8 A;  1KXP D;  4FIP B;  4C31 B;  5BPK A;  4E99 A;  4F5T A;  3ECP A;  3NVK A;  4GDK B;  2AJE A;  1E7B A;  1IJG A;  3LU6 A;  1J7E A;  2XVU A;  5GIN A;  2YDF A;  1HK5 A;  1UOR A;  1AO6 A;  1E7H A;  2DYO A;  3BPJ A;  2BX8 A;  4K71 A;  4W4U B;  5DQF A;  5GIP A;  1LNS A;  1MM8 A;  1MUS A;  4I9O A;  2LXS A;  3A75 A;  4L9Q A;  4LUF A;  2BXE A;  2EFH A;  1FOU A;  2Z8K A;  5HOZ A;  3V08 A;  2BXP A;  2BXO A;  3H3A A;  3SQJ A;  2XW1 A;  3PLA A;  3B9L A;  1VFI A;  4F5U A;  4BY9 C;  1MIV A;  1E7A A;  2Z8I A;  2Z8J A;  3G9K D;  2EFE A;  2BXF A;  4NAW B;  4FK5 B;  1VZS A;  4BKE A;  5IJF A;  5IJ5 A;  2QHB A;  2DBU A;  4N3Z A;  2LQH A;  2QMC A;  4HGK A;  2KBZ A;  1J78 A;  4N0F D;  2BXK A;  1JNB A;  4D7X A;  3WHQ A;  2LOQ A;  3TDL A;  2BXH A;  2XW0 A;  4IW1 A;  2K0N A;  4EMX A;  4PO0 A;  3W1S A;  2GUT A;  2ROH A;  5D7G A;  2I30 A;  4LB2 A;  2XMO A;  3H37 A;  2CKX A;  1BM0 A;  5ID7 A;  3FNM A;  2LXT A;  3UIV A;  3GQU A;  2AGH B;  2BXL A;  3NMU A;  4OTT A;  1E7G A;  5IIH A;  1SB0 A;  2DYM A;  4FJC B;  4S1Y A;  2BXG A;  4ZCG A;  2BXQ A;  4LA0 A;  5DBY A;  2BXB A;  1GNI A;  1N5U A;  2KWF A;  1TF0 A;  2DBX A;  1E7E A;  2VUF A;  3JRY A;  3SIV B;  3GQX A;  1LOT A;  3WHS A;  1HK4 A;  2EFD A;  1HK2 A;  2BXD A;  2NNW A;  2XVQ A;  4N0U D;  3GA9 L;  4F5V A;  4OR0 A;  5GIO A;  1MIW A;  1GNJ A;  3NVI A; 
#chains in the Genus database with same CATH homology
 5FUO A;  4MBE C;  1MIY A;  3MHH B;  4J2V A;  4L9K A;  4TQ0 A;  3KJL A;  2E0Y A;  3M99 C;  3CX9 A;  2BXI A;  2XVV A;  1KW2 A;  2NQO A;  2BXC A;  4HGM B;  1HK1 A;  3A73 A;  4L8U A;  3MHS B;  1HK3 A;  5ID9 A;  2VUE A;  2BXM A;  4GG2 A;  2EFC A;  1TXU A;  5IJE A;  3SIU B;  2XVW A;  3WHR A;  4G03 A;  3V03 A;  2QM6 A;  4ZBK A;  1H9Z A;  2V36 A;  4ZBQ A;  1E7C A;  1MA9 A;  4ZBR A;  5IIX A;  3VQI A;  2BXA A;  1BKE A;  2I2Z A;  4TQ1 A;  4GDX A;  4LUH A;  4IW2 A;  4K2C A;  4ZUX V;  2E0X A;  2OT3 A;  4LB9 A;  5B5T A;  1E7I A;  2DG5 A;  1E7F A;  3FWC C;  3KIK A;  3ICX A;  1NT2 B;  4F5S A;  4Z9O A;  4G01 A;  1H5W A;  1O9X A;  4Z69 A;  3JQZ A;  1BJ5 A;  4G04 A;  2DBW A;  3NVM A;  4M70 B;  3LU7 A;  3FWB C;  5GHK A;  5IIU A;  1E78 A;  4ZC6 A;  4JK4 A;  2XSI A;  2VDB A;  2JUH A;  2BXN A;  3V09 A;  4DHX B;  4WA6 B;  4GDL B;  1HA2 A;  4OTU A;  2OZB B;  5IFO A;  3B9M A;  4OT2 A;  3LU8 A;  1KXP D;  4FIP B;  4C31 B;  5BPK A;  4E99 A;  4F5T A;  3NVK A;  4GDK B;  2AJE A;  1E7B A;  1IJG A;  3LU6 A;  1J7E A;  2XVU A;  5GIN A;  2YDF A;  1HK5 A;  1UOR A;  1AO6 A;  1E7H A;  2DYO A;  5GIP A;  2BX8 A;  4K71 A;  4W4U B;  5DQF A;  1LNS A;  3A75 A;  4L9Q A;  4LUF A;  2BXE A;  2EFH A;  1FOU A;  2Z8K A;  5HOZ A;  3V08 A;  2BXP A;  2BXO A;  3H3A A;  3SQJ A;  2XW1 A;  3PLA A;  3B9L A;  1VFI A;  4F5U A;  4BY9 C;  1MIV A;  1E7A A;  2Z8I A;  2Z8J A;  3G9K D;  2EFE A;  2BXF A;  4NAW B;  4FK5 B;  1VZS A;  4BKE A;  5IJF A;  5IJ5 A;  2QHB A;  2DBU A;  4N3Z A;  2QMC A;  4HGK A;  2KBZ A;  1J78 A;  4N0F D;  2BXK A;  1JNB A;  3WHQ A;  2LOQ A;  3TDL A;  2BXH A;  2XW0 A;  4IW1 A;  4EMX A;  4PO0 A;  3W1S A;  2ROH A;  5D7G A;  2I30 A;  4LB2 A;  2XMO A;  3H37 A;  2CKX A;  1BM0 A;  5ID7 A;  3FNM A;  3UIV A;  3GQU A;  2BXL A;  3NMU A;  4OTT A;  1E7G A;  5IIH A;  2DYM A;  4FJC B;  4S1Y A;  2BXG A;  4ZCG A;  2BXQ A;  4LA0 A;  5DBY A;  2BXB A;  1GNI A;  1N5U A;  1TF0 A;  2DBX A;  1E7E A;  2VUF A;  3JRY A;  3SIV B;  3GQX A;  1LOT A;  3WHS A;  1HK4 A;  2EFD A;  1HK2 A;  2BXD A;  2NNW A;  2XVQ A;  4N0U D;  3GA9 L;  4F5V A;  4OR0 A;  5GIO A;  1MIW A;  1GNJ A;  3NVI A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4IW1A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations