4IW2A

Hsa-glucose complex
Total Genus 218
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural mechanism of ring-opening reaction of glucose by human serum albumin
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Serum albumin
total genus 218
structure length 578
sequence length 578
ec nomenclature
pdb deposition date 2013-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A05
1O9XA 2I30A 2XW0A 5IIUA 4LUFA 4J2VA 2BXPA 3CX9A 1E7IA 4N0UD 3TDLA 1BKEA 4LB2A 4IW2A 1LOTA 1E7CA 1HK4A 2BX8A 4BKEA 4K2CA 4K71A 1BJ5A 4S1YA 2BXAA 2BXIA 4EMXA 5GHKA 1TF0A 4F5UA 5IIHA 2BXCA 1E7BA 1H9ZA 3V03A 4N0FD 2XVUA 5ID9A 4F5TA 4G03A 4F5SA 3LU7A 1BM0A 1KW2A 2BXFA 2BXLA 4PO0A 3LU6A 2XSIA 1J7EA 3JQZA 3V08A 2BXGA 2XVQA 4ZBQA 1N5UA 2XVVA 5DQFA 4HGKA 1GNJA 2BXNA 5IFOA 4IW1A 1E7GA 2BXEA 3A73A 3UIVA 4LB9A 1E7HA 2BXBA 4F5VA 1HK5A 1GNIA 3B9MA 1HK2A 1KXPD 2VUFA 3SQJA 1AO6A 3JRYA 2BXKA 5IJFA 3LU8A 4LA0A 4ZBRA 1HK3A 3B9LA 4L8UA 4G04A 5ID7A 4L9KA 5IJ5A 1HA2A 4HGMB 5IIXA 4L9QA 1E78A 2BXHA 5HOZA 1E7EA 2BXOA 2VDBA 2XW1A 4OT2A 1J78A 4Z69A 2BXMA 1E7AA 4LUHA 1HK1A 2BXDA 4JK4A 1UORA 2XVWA 3V09A 2I2ZA 5DBYA 5FUOA 1E7FA 2VUEA 2BXQA 4E99A 2YDFA 5IJEA 4OR0A 1MA9A
chains in the Genus database with same CATH superfamily
2EFEA 5D7GA 1O9XA 2I30A 2XW0A 4GG2A 5IIUA 4TQ0A 2EFDA 4LUFA 4J2VA 2BXPA 3CX9A 1E7IA 1IJGA 2ROHA 4N0UD 3TDLA 3VQIA 2KWFA 1BKEA 1FOUA 4LB2A 4IW2A 1LOTA 3FNMA 2LQIA 1E7CA 1HK4A 4D7XA 2BX8A 3KJLA 4BKEA 4K2CA 4K71A 1BJ5A 2EFHA 1VFIA 1VZSA 4S1YA 3MHSB 2DG5A 1MIWA 2BXAA 4GDXA 2BXIA 4OTTA 2AJEA 4EMXA 5GHKA 1LNSA 1TXUA 1TF0A 3GQXA 4F5UA 5IIHA 2LOQA 2BXCA 1E7BA 3H3AA 2LQHA 4GDKB 1H9ZA 3V03A 2QMCA 3FWBC 4G01A 2OT3A 4N0FD 2XVUA 5ID9A 4WA6B 4F5TA 4TQ1A 4G03A 3BPJA 4FIPB 2DYMA 2XMOA 3LU7A 4F5SA 1BM0A 1KW2A 2BXFA 5GIOA 5GIPA 4ZC6A 2BXLA 4PO0A 3LU6A 2XSIA 1J7EA 3JQZA 3V08A 2BXGA 2XVQA 4ZBQA 1N5UA 2XVVA 5DQFA 2OZBB 3NVMA 3SIUB 3ICXA 4FK5B 4N3ZA 2Z8IA 4HGKA 1GNJA 1SB0A 2BXNA 5IFOA 2E0XA 4IW1A 1E7GA 3KIKA 2DYOA 2BXEA 3A73A 3UIVA 4M70B 4LB9A 2KBZA 1E7HA 4I9OA 5BPKA 2BXBA 1MM8A 4F5VA 1HK5A 1GNIA 3A75A 3B9MA 1NT2B 2JUHA 1MUSA 1KDXA 5B5TA 3G9KD 4C31B 1HK2A 1KXPD 2VUFA 3SQJA 1AO6A 3JRYA 2BXKA 4W4UB 5IJFA 3WHRA 2E0YA 2Z8JA 4OTUA 3LU8A 2CKXA 4LA0A 2EFCA 4DHXB 1JNBA 4ZBRA 1HK3A 3B9LA 4L8UA 4G04A 3W1SA 4L9KA 5IJ5A 2V36A 1HA2A 5ID7A 4HGMB 1H5WA 4FJCB 2NNWA 5IIXA 3NMUA 3M99C 2GUTA 2NQOA 1E78A 4L9QA 4NAWB 2BXHA 2QHBA 1MUHA 5HOZA 4MBEC 1E7EA 3PLAA 3GQUA 2QM6A 2BXOA 2VDBA 3GA9L 3WHSA 5GINA 3NVIA 2XW1A 4OT2A 1J78A 3FWCC 4Z69A 2BXMA 1E7AA 4LUHA 4GDLB 2DBXA 4ZUXV 3ECPA 3MHHB 2LXSA 2Z8KA 1HK1A 2BXDA 2DBUA 4JK4A 1UORA 2AGHB 2XVWA 3V09A 2I2ZA 5DBYA 5FUOA 2K0NA 3H37A 4BY9C 1E7FA 1MIYA 1MIVA 2VUEA 3WHQA 3NVKA 4DM0A 2BXQA 3SIVB 4E99A 2LXTA 2YDFA 4Z9OA 4ZCGA 4OR0A 2DBWA 5IJEA 4ZBKA 1MA9A
chains in the Genus database with same CATH topology
2EFEA 5D7GA 1O9XA 2I30A 2XW0A 4GG2A 5IIUA 4TQ0A 2EFDA 4LUFA 4J2VA 2BXPA 3CX9A 1E7IA 1IJGA 2ROHA 4N0UD 3TDLA 3VQIA 1BKEA 1FOUA 4LB2A 4IW2A 1LOTA 3FNMA 1E7CA 1HK4A 2BX8A 3KJLA 4BKEA 4K2CA 4K71A 1BJ5A 2EFHA 1VFIA 1VZSA 4S1YA 3MHSB 2DG5A 1MIWA 2BXAA 4GDXA 2BXIA 4OTTA 2AJEA 4EMXA 5GHKA 1LNSA 1TXUA 1TF0A 3GQXA 4F5UA 5IIHA 2LOQA 2BXCA 1E7BA 3H3AA 4GDKB 1H9ZA 3V03A 2QMCA 3FWBC 4G01A 2OT3A 4N0FD 2XVUA 5ID9A 4WA6B 4F5TA 4TQ1A 4G03A 4FIPB 4F5SA 2DYMA 2XMOA 3LU7A 5GIOA 1BM0A 1KW2A 2BXFA 5GIPA 4ZC6A 2BXLA 4PO0A 3LU6A 2XSIA 1J7EA 3JQZA 3V08A 2BXGA 2XVQA 4ZBQA 1N5UA 2XVVA 5DQFA 2OZBB 3NVMA 3SIUB 3ICXA 4FK5B 4N3ZA 2Z8IA 4HGKA 1GNJA 2BXNA 5IFOA 2E0XA 4IW1A 1E7GA 3KIKA 2DYOA 2BXEA 3A73A 3UIVA 4M70B 4LB9A 2KBZA 1E7HA 5BPKA 2BXBA 4F5VA 1HK5A 1GNIA 3A75A 3B9MA 1NT2B 2JUHA 5B5TA 3G9KD 4C31B 1HK2A 1KXPD 2VUFA 3SQJA 1AO6A 3JRYA 2BXKA 4W4UB 5IJFA 3WHRA 2E0YA 2Z8JA 4OTUA 3LU8A 2CKXA 4LA0A 2EFCA 4DHXB 1JNBA 4ZBRA 1HK3A 3B9LA 4L8UA 4G04A 3W1SA 4L9KA 5IJ5A 2V36A 1HA2A 5ID7A 4HGMB 1H5WA 4FJCB 2NNWA 5IIXA 3NMUA 3M99C 2NQOA 1E78A 4L9QA 4NAWB 2BXHA 2QHBA 5HOZA 4MBEC 1E7EA 3PLAA 3GQUA 2QM6A 2BXOA 2VDBA 3GA9L 3WHSA 5GINA 3NVIA 2XW1A 4OT2A 1J78A 3FWCC 4Z69A 2BXMA 1E7AA 4LUHA 4GDLB 2DBXA 4ZUXV 3MHHB 2Z8KA 1HK1A 2BXDA 2DBUA 4JK4A 1UORA 2XVWA 3V09A 2I2ZA 5DBYA 5FUOA 3H37A 4BY9C 1E7FA 1MIYA 1MIVA 2VUEA 3WHQA 3NVKA 2BXQA 3SIVB 4E99A 2YDFA 4Z9OA 4ZCGA 5IJEA 4OR0A 2DBWA 4ZBKA 1MA9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O9X A;  2I30 A;  2XW0 A;  5IIU A;  4LUF A;  4J2V A;  2BXP A;  3CX9 A;  1E7I A;  4N0U D;  3TDL A;  1BKE A;  4LB2 A;  4IW2 A;  1LOT A;  1E7C A;  1HK4 A;  2BX8 A;  4BKE A;  4K2C A;  4K71 A;  1BJ5 A;  4S1Y A;  2BXA A;  2BXI A;  4EMX A;  5GHK A;  1TF0 A;  4F5U A;  5IIH A;  2BXC A;  1E7B A;  1H9Z A;  3V03 A;  4N0F D;  2XVU A;  5ID9 A;  4F5T A;  4G03 A;  4F5S A;  3LU7 A;  1BM0 A;  1KW2 A;  2BXF A;  2BXL A;  4PO0 A;  3LU6 A;  2XSI A;  1J7E A;  3JQZ A;  3V08 A;  2BXG A;  2XVQ A;  4ZBQ A;  1N5U A;  2XVV A;  5DQF A;  4HGK A;  1GNJ A;  2BXN A;  5IFO A;  4IW1 A;  1E7G A;  2BXE A;  3A73 A;  3UIV A;  4LB9 A;  1E7H A;  2BXB A;  4F5V A;  1HK5 A;  1GNI A;  3B9M A;  1HK2 A;  1KXP D;  2VUF A;  3SQJ A;  1AO6 A;  3JRY A;  2BXK A;  5IJF A;  3LU8 A;  4LA0 A;  4ZBR A;  1HK3 A;  3B9L A;  4L8U A;  4G04 A;  5ID7 A;  4L9K A;  5IJ5 A;  1HA2 A;  4HGM B;  5IIX A;  4L9Q A;  1E78 A;  2BXH A;  5HOZ A;  1E7E A;  2BXO A;  2VDB A;  2XW1 A;  4OT2 A;  1J78 A;  4Z69 A;  2BXM A;  1E7A A;  4LUH A;  1HK1 A;  2BXD A;  4JK4 A;  1UOR A;  2XVW A;  3V09 A;  2I2Z A;  5DBY A;  5FUO A;  1E7F A;  2VUE A;  2BXQ A;  4E99 A;  2YDF A;  5IJE A;  4OR0 A;  1MA9 A; 
#chains in the Genus database with same CATH topology
 2EFE A;  5D7G A;  1O9X A;  2I30 A;  2XW0 A;  4GG2 A;  5IIU A;  4TQ0 A;  2EFD A;  4LUF A;  4J2V A;  2BXP A;  3CX9 A;  1E7I A;  1IJG A;  2ROH A;  4N0U D;  3TDL A;  3VQI A;  2KWF A;  1BKE A;  1FOU A;  4LB2 A;  4IW2 A;  1LOT A;  3FNM A;  2LQI A;  1E7C A;  1HK4 A;  4D7X A;  2BX8 A;  3KJL A;  4BKE A;  4K2C A;  4K71 A;  1BJ5 A;  2EFH A;  1VFI A;  1VZS A;  4S1Y A;  3MHS B;  2DG5 A;  1MIW A;  2BXA A;  4GDX A;  2BXI A;  4OTT A;  2AJE A;  4EMX A;  5GHK A;  1LNS A;  1TXU A;  1TF0 A;  3GQX A;  4F5U A;  5IIH A;  2LOQ A;  2BXC A;  1E7B A;  3H3A A;  2LQH A;  4GDK B;  1H9Z A;  3V03 A;  2QMC A;  3FWB C;  4G01 A;  2OT3 A;  4N0F D;  2XVU A;  5ID9 A;  4WA6 B;  4F5T A;  4TQ1 A;  4G03 A;  3BPJ A;  4FIP B;  2DYM A;  2XMO A;  3LU7 A;  4F5S A;  1BM0 A;  1KW2 A;  2BXF A;  5GIO A;  5GIP A;  4ZC6 A;  2BXL A;  4PO0 A;  3LU6 A;  2XSI A;  1J7E A;  3JQZ A;  3V08 A;  2BXG A;  2XVQ A;  4ZBQ A;  1N5U A;  2XVV A;  5DQF A;  2OZB B;  3NVM A;  3SIU B;  3ICX A;  4FK5 B;  4N3Z A;  2Z8I A;  4HGK A;  1GNJ A;  1SB0 A;  2BXN A;  5IFO A;  2E0X A;  4IW1 A;  1E7G A;  3KIK A;  2DYO A;  2BXE A;  3A73 A;  3UIV A;  4M70 B;  4LB9 A;  2KBZ A;  1E7H A;  4I9O A;  5BPK A;  2BXB A;  1MM8 A;  4F5V A;  1HK5 A;  1GNI A;  3A75 A;  3B9M A;  1NT2 B;  2JUH A;  1MUS A;  1KDX A;  5B5T A;  3G9K D;  4C31 B;  1HK2 A;  1KXP D;  2VUF A;  3SQJ A;  1AO6 A;  3JRY A;  2BXK A;  4W4U B;  5IJF A;  3WHR A;  2E0Y A;  2Z8J A;  4OTU A;  3LU8 A;  2CKX A;  4LA0 A;  2EFC A;  4DHX B;  1JNB A;  4ZBR A;  1HK3 A;  3B9L A;  4L8U A;  4G04 A;  3W1S A;  4L9K A;  5IJ5 A;  2V36 A;  1HA2 A;  5ID7 A;  4HGM B;  1H5W A;  4FJC B;  2NNW A;  5IIX A;  3NMU A;  3M99 C;  2GUT A;  2NQO A;  1E78 A;  4L9Q A;  4NAW B;  2BXH A;  2QHB A;  1MUH A;  5HOZ A;  4MBE C;  1E7E A;  3PLA A;  3GQU A;  2QM6 A;  2BXO A;  2VDB A;  3GA9 L;  3WHS A;  5GIN A;  3NVI A;  2XW1 A;  4OT2 A;  1J78 A;  3FWC C;  4Z69 A;  2BXM A;  1E7A A;  4LUH A;  4GDL B;  2DBX A;  4ZUX V;  3ECP A;  3MHH B;  2LXS A;  2Z8K A;  1HK1 A;  2BXD A;  2DBU A;  4JK4 A;  1UOR A;  2AGH B;  2XVW A;  3V09 A;  2I2Z A;  5DBY A;  5FUO A;  2K0N A;  3H37 A;  4BY9 C;  1E7F A;  1MIY A;  1MIV A;  2VUE A;  3WHQ A;  3NVK A;  4DM0 A;  2BXQ A;  3SIV B;  4E99 A;  2LXT A;  2YDF A;  4Z9O A;  4ZCG A;  4OR0 A;  2DBW A;  5IJE A;  4ZBK A;  1MA9 A; 
#chains in the Genus database with same CATH homology
 2EFE A;  5D7G A;  1O9X A;  2I30 A;  2XW0 A;  4GG2 A;  5IIU A;  4TQ0 A;  2EFD A;  4LUF A;  4J2V A;  2BXP A;  3CX9 A;  1E7I A;  1IJG A;  2ROH A;  4N0U D;  3TDL A;  3VQI A;  1BKE A;  1FOU A;  4LB2 A;  4IW2 A;  1LOT A;  3FNM A;  1E7C A;  1HK4 A;  2BX8 A;  3KJL A;  4BKE A;  4K2C A;  4K71 A;  1BJ5 A;  2EFH A;  1VFI A;  1VZS A;  4S1Y A;  3MHS B;  2DG5 A;  1MIW A;  2BXA A;  4GDX A;  2BXI A;  4OTT A;  2AJE A;  4EMX A;  5GHK A;  1LNS A;  1TXU A;  1TF0 A;  3GQX A;  4F5U A;  5IIH A;  2LOQ A;  2BXC A;  1E7B A;  3H3A A;  4GDK B;  1H9Z A;  3V03 A;  2QMC A;  3FWB C;  4G01 A;  2OT3 A;  4N0F D;  2XVU A;  5ID9 A;  4WA6 B;  4F5T A;  4TQ1 A;  4G03 A;  4FIP B;  4F5S A;  2DYM A;  2XMO A;  3LU7 A;  5GIO A;  1BM0 A;  1KW2 A;  2BXF A;  5GIP A;  4ZC6 A;  2BXL A;  4PO0 A;  3LU6 A;  2XSI A;  1J7E A;  3JQZ A;  3V08 A;  2BXG A;  2XVQ A;  4ZBQ A;  1N5U A;  2XVV A;  5DQF A;  2OZB B;  3NVM A;  3SIU B;  3ICX A;  4FK5 B;  4N3Z A;  2Z8I A;  4HGK A;  1GNJ A;  2BXN A;  5IFO A;  2E0X A;  4IW1 A;  1E7G A;  3KIK A;  2DYO A;  2BXE A;  3A73 A;  3UIV A;  4M70 B;  4LB9 A;  2KBZ A;  1E7H A;  5BPK A;  2BXB A;  4F5V A;  1HK5 A;  1GNI A;  3A75 A;  3B9M A;  1NT2 B;  2JUH A;  5B5T A;  3G9K D;  4C31 B;  1HK2 A;  1KXP D;  2VUF A;  3SQJ A;  1AO6 A;  3JRY A;  2BXK A;  4W4U B;  5IJF A;  3WHR A;  2E0Y A;  2Z8J A;  4OTU A;  3LU8 A;  2CKX A;  4LA0 A;  2EFC A;  4DHX B;  1JNB A;  4ZBR A;  1HK3 A;  3B9L A;  4L8U A;  4G04 A;  3W1S A;  4L9K A;  5IJ5 A;  2V36 A;  1HA2 A;  5ID7 A;  4HGM B;  1H5W A;  4FJC B;  2NNW A;  5IIX A;  3NMU A;  3M99 C;  2NQO A;  1E78 A;  4L9Q A;  4NAW B;  2BXH A;  2QHB A;  5HOZ A;  4MBE C;  1E7E A;  3PLA A;  3GQU A;  2QM6 A;  2BXO A;  2VDB A;  3GA9 L;  3WHS A;  5GIN A;  3NVI A;  2XW1 A;  4OT2 A;  1J78 A;  3FWC C;  4Z69 A;  2BXM A;  1E7A A;  4LUH A;  4GDL B;  2DBX A;  4ZUX V;  3MHH B;  2Z8K A;  1HK1 A;  2BXD A;  2DBU A;  4JK4 A;  1UOR A;  2XVW A;  3V09 A;  2I2Z A;  5DBY A;  5FUO A;  3H37 A;  4BY9 C;  1E7F A;  1MIY A;  1MIV A;  2VUE A;  3WHQ A;  3NVK A;  2BXQ A;  3SIV B;  4E99 A;  2YDF A;  4Z9O A;  4ZCG A;  5IJE A;  4OR0 A;  2DBW A;  4ZBK A;  1MA9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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