4K71 | Genus

Total Genus 223

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	223
sequence length	583
structure length	583
Chain Sequence	HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQMSAPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAGTFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAAMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Lipid transport
source organism	Homo sapiens
publication title	Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface. pubmed doi rcsb
molecule keywords	Serum albumin
total genus	223
structure length	583
sequence length	583
chains with identical sequence	D
ec nomenclature
pdb deposition date	2013-04-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4k71A03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4k71A02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4k71A04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4k71A01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4k71A05
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4k71A06

2BXFA 1UORA 3B9MA 5IFOA 2BXPA 3V09A 4F5SA 3B9LA 2XVUA 4K2CA 4F5UA 1E7AA 4S1YA 3LU6A 3LU8A 4HGKA 2BXMA 5IJEA 2XVVA 1E7CA 1HK5A 1HK4A 2VUEA 3JRYA 4LUHA 4L9QA 1J7EA 3UIVA 1H9ZA 4F5TA 4G04A 1MA9A 1HK1A 1TF0A 2VDBA 2BXLA 3JQZA 1BKEA 4EMXA 5FUOA 5IJ5A 5IIUA 4L9KA 4Z69A 3V08A 2BXOA 3CX9A 4G03A 1KXPD 2BXIA 1J78A 4J2VA 1KW2A 4N0FD 5DBYA 3A73A 1GNJA 4OR0A 2XSIA 4K71A 2I2ZA 2BXEA 1E7IA 5IIHA 5GHKA 4ZBRA 2I30A 4IW1A 2BXNA 4N0UD 1E7HA 1O9XA 3V03A 2BXDA 4IW2A 1E7EA 4PO0A 1E7BA 4OT2A 5ID7A 4LB2A 2BXKA 1BM0A 4F5VA 4L8UA 1N5UA 2XW1A 4BKEA 1AO6A 1HA2A 2XVQA 2XW0A 2BXBA 2BXGA 1BJ5A 3SQJA 2BXAA 5IIXA 5IJFA 4HGMB 1E7FA 1LOTA 4LA0A 1E7GA 1E78A 1GNIA 2XVWA 5DQFA 3TDLA 4LB9A 2BXCA 4LUFA 3LU7A 4ZBQA 4E99A 2BXHA 5ID9A 2YDFA 4JK4A 2BXQA 1HK2A 2BX8A 1HK3A 2VUFA 5HOZA
chains in the Genus database with same CATH superfamily

3MHSB 2BXFA 1UORA 3B9MA 5IFOA 1NT2B 4Z9OA 2BXPA 2LQHA 3V09A 4F5SA 3B9LA 2LXSA 2XVUA 4K2CA 4F5UA 1E7AA 3GQUA 4S1YA 4DHXB 3LU6A 3LU8A 4ZCGA 4HGKA 2NQOA 4ZBKA 2NNWA 3ECPA 2BXMA 5IJEA 4GDLB 2XVVA 3FWBC 1E7CA 1MUSA 1HK5A 1HK4A 2VUEA 3NVIA 1TXUA 3JRYA 3WHSA 4ZC6A 4C31B 3GA9L 2EFDA 4LUHA 4L9QA 1MM8A 1J7EA 3UIVA 1H9ZA 4F5TA 4WA6B 4G04A 1MA9A 1HK1A 1TF0A 1VZSA 2VDBA 2BXLA 3JQZA 2KWFA 1BKEA 2DBUA 4M70B 5GIPA 4EMXA 5FUOA 2OZBB 5IJ5A 4ZUXV 5IIUA 2GUTA 3BPJA 4L9KA 4TQ1A 2CKXA 2XMOA 3W1SA 4Z69A 2DYMA 3V08A 2QHBA 4GG2A 3PLAA 2BXOA 2JUHA 3KJLA 3CX9A 4G03A 4TQ0A 1KXPD 2BXIA 1J78A 1MUHA 3KIKA 4J2VA 1H5WA 1KW2A 4N0FD 4OTTA 3A73A 3FNMA 5DBYA 4OTUA 4FIPB 1GNJA 2E0YA 3ICXA 2ROHA 4OR0A 2XSIA 4D7XA 1KDXA 4K71A 4W4UB 2I2ZA 2BXEA 4GDKB 2EFEA 1VFIA 1SB0A 1E7IA 5IIHA 1IJGA 3FWCC 2Z8JA 2I30A 5GHKA 2DG5A 2LOQA 4IW1A 1MIVA 4ZBRA 4DM0A 2BXNA 4N0UD 1E7HA 4N3ZA 3NVKA 5B5TA 1O9XA 3V03A 3SIVB 1MIYA 2BXDA 2QMCA 4IW2A 2AGHB 4G01A 1E7EA 4PO0A 1E7BA 3VQIA 4OT2A 5ID7A 2KBZA 2AJEA 4LB2A 2BXKA 2Z8IA 1BM0A 4F5VA 2QM6A 4GDXA 3WHQA 2DBXA 2LXTA 2LQIA 2OT3A 4FJCB 4L8UA 1N5UA 2DYOA 2XW1A 4BKEA 2DBWA 1AO6A 1HA2A 3NVMA 2XVQA 2XW0A 1LNSA 2V36A 2BXBA 3MHHB 3NMUA 2K0NA 2BXGA 4MBEC 3M99C 1BJ5A 3SQJA 4BY9C 2EFCA 2BXAA 5IIXA 3SIUB 5IJFA 4HGMB 1E7FA 5BPKA 1LOTA 4LA0A 1E7GA 5GIOA 1E78A 3WHRA 1MIWA 1GNIA 2XVWA 5DQFA 2Z8KA 5D7GA 4NAWB 4LB9A 3TDLA 2BXCA 4LUFA 3LU7A 4ZBQA 4E99A 2EFHA 1FOUA 2BXHA 2E0XA 3H37A 5ID9A 2YDFA 5GINA 3H3AA 3GQXA 4FK5B 3A75A 2BXQA 1HK2A 4JK4A 2BX8A 1HK3A 4I9OA 1JNBA 3G9KD 2VUFA 5HOZA
chains in the Genus database with same CATH topology

3MHSB 2BXFA 1UORA 3B9MA 5IFOA 1NT2B 4Z9OA 2BXPA 3V09A 4F5SA 3B9LA 2XVUA 4K2CA 4F5UA 1E7AA 3GQUA 4S1YA 4DHXB 3LU6A 3LU8A 4ZCGA 4HGKA 2NQOA 4ZBKA 2NNWA 2BXMA 5IJEA 4GDLB 2XVVA 3FWBC 1E7CA 1HK5A 1HK4A 2VUEA 3NVIA 1TXUA 3JRYA 3WHSA 4ZC6A 4C31B 3GA9L 2EFDA 4LUHA 4L9QA 1J7EA 3UIVA 1H9ZA 4F5TA 4WA6B 4G04A 1MA9A 1HK1A 1TF0A 1VZSA 2VDBA 2BXLA 3JQZA 1BKEA 2DBUA 4M70B 5GIPA 4EMXA 5FUOA 2OZBB 5IJ5A 4ZUXV 5IIUA 4L9KA 4TQ1A 2CKXA 2XMOA 3W1SA 4Z69A 2DYMA 3V08A 2QHBA 4GG2A 3PLAA 2BXOA 2JUHA 3KJLA 3CX9A 4G03A 4TQ0A 1KXPD 2BXIA 1J78A 3KIKA 4J2VA 1H5WA 1KW2A 4N0FD 4OTTA 3A73A 3FNMA 5DBYA 4OTUA 4FIPB 1GNJA 2E0YA 3ICXA 2ROHA 4OR0A 2XSIA 4K71A 4W4UB 2I2ZA 2BXEA 4GDKB 2EFEA 1VFIA 1E7IA 5IIHA 1IJGA 3FWCC 2Z8JA 2I30A 5GHKA 2DG5A 2LOQA 4IW1A 1MIVA 4ZBRA 2BXNA 4N0UD 1E7HA 4N3ZA 3NVKA 5B5TA 1O9XA 3V03A 3SIVB 1MIYA 2BXDA 2QMCA 4IW2A 4G01A 1E7EA 4PO0A 1E7BA 3VQIA 4OT2A 5ID7A 2KBZA 2AJEA 4LB2A 2BXKA 2Z8IA 1BM0A 4F5VA 2QM6A 4GDXA 3WHQA 2DBXA 4FJCB 2OT3A 4L8UA 1N5UA 2DYOA 2XW1A 4BKEA 2DBWA 1AO6A 1HA2A 3NVMA 2XVQA 2XW0A 1LNSA 2V36A 2BXBA 3MHHB 3NMUA 4MBEC 2BXGA 3M99C 1BJ5A 3SQJA 4BY9C 2EFCA 2BXAA 5IIXA 3SIUB 5IJFA 4HGMB 1E7FA 5BPKA 1LOTA 4LA0A 1E7GA 5GIOA 1E78A 3WHRA 1MIWA 1GNIA 2XVWA 5DQFA 2Z8KA 5D7GA 4NAWB 4LB9A 3TDLA 2BXCA 4LUFA 3LU7A 4ZBQA 4E99A 2EFHA 1FOUA 2BXHA 2E0XA 3H37A 5ID9A 2YDFA 5GINA 3H3AA 3GQXA 4FK5B 3A75A 2BXQA 1HK2A 4JK4A 2BX8A 1HK3A 1JNBA 3G9KD 2VUFA 5HOZA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2BXF A;  1UOR A;  3B9M A;  5IFO A;  2BXP A;  3V09 A;  4F5S A;  3B9L A;  2XVU A;  4K2C A;  4F5U A;  1E7A A;  4S1Y A;  3LU6 A;  3LU8 A;  4HGK A;  2BXM A;  5IJE A;  2XVV A;  1E7C A;  1HK5 A;  1HK4 A;  2VUE A;  3JRY A;  4LUH A;  4L9Q A;  1J7E A;  3UIV A;  1H9Z A;  4F5T A;  4G04 A;  1MA9 A;  1HK1 A;  1TF0 A;  2VDB A;  2BXL A;  3JQZ A;  1BKE A;  4EMX A;  5FUO A;  5IJ5 A;  5IIU A;  4L9K A;  4Z69 A;  3V08 A;  2BXO A;  3CX9 A;  4G03 A;  1KXP D;  2BXI A;  1J78 A;  4J2V A;  1KW2 A;  4N0F D;  5DBY A;  3A73 A;  1GNJ A;  4OR0 A;  2XSI A;  4K71 A;  2I2Z A;  2BXE A;  1E7I A;  5IIH A;  5GHK A;  4ZBR A;  2I30 A;  4IW1 A;  2BXN A;  4N0U D;  1E7H A;  1O9X A;  3V03 A;  2BXD A;  4IW2 A;  1E7E A;  4PO0 A;  1E7B A;  4OT2 A;  5ID7 A;  4LB2 A;  2BXK A;  1BM0 A;  4F5V A;  4L8U A;  1N5U A;  2XW1 A;  4BKE A;  1AO6 A;  1HA2 A;  2XVQ A;  2XW0 A;  2BXB A;  2BXG A;  1BJ5 A;  3SQJ A;  2BXA A;  5IIX A;  5IJF A;  4HGM B;  1E7F A;  1LOT A;  4LA0 A;  1E7G A;  1E78 A;  1GNI A;  2XVW A;  5DQF A;  3TDL A;  4LB9 A;  2BXC A;  4LUF A;  3LU7 A;  4ZBQ A;  4E99 A;  2BXH A;  5ID9 A;  2YDF A;  4JK4 A;  2BXQ A;  1HK2 A;  2BX8 A;  1HK3 A;  2VUF A;  5HOZ A; 
#chains in the Genus database with same CATH topology
 3MHS B;  2BXF A;  1UOR A;  3B9M A;  5IFO A;  1NT2 B;  4Z9O A;  2BXP A;  2LQH A;  3V09 A;  4F5S A;  3B9L A;  2LXS A;  2XVU A;  4K2C A;  4F5U A;  1E7A A;  3GQU A;  4S1Y A;  4DHX B;  3LU6 A;  3LU8 A;  4ZCG A;  4HGK A;  2NQO A;  4ZBK A;  2NNW A;  3ECP A;  2BXM A;  5IJE A;  4GDL B;  2XVV A;  3FWB C;  1E7C A;  1MUS A;  1HK5 A;  1HK4 A;  2VUE A;  3NVI A;  1TXU A;  3JRY A;  3WHS A;  4ZC6 A;  4C31 B;  3GA9 L;  2EFD A;  4LUH A;  4L9Q A;  1MM8 A;  1J7E A;  3UIV A;  1H9Z A;  4F5T A;  4WA6 B;  4G04 A;  1MA9 A;  1HK1 A;  1TF0 A;  1VZS A;  2VDB A;  2BXL A;  3JQZ A;  2KWF A;  1BKE A;  2DBU A;  4M70 B;  5GIP A;  4EMX A;  5FUO A;  2OZB B;  5IJ5 A;  4ZUX V;  5IIU A;  2GUT A;  3BPJ A;  4L9K A;  4TQ1 A;  2CKX A;  2XMO A;  3W1S A;  4Z69 A;  2DYM A;  3V08 A;  2QHB A;  4GG2 A;  3PLA A;  2BXO A;  2JUH A;  3KJL A;  3CX9 A;  4G03 A;  4TQ0 A;  1KXP D;  2BXI A;  1J78 A;  1MUH A;  3KIK A;  4J2V A;  1H5W A;  1KW2 A;  4N0F D;  4OTT A;  3A73 A;  3FNM A;  5DBY A;  4OTU A;  4FIP B;  1GNJ A;  2E0Y A;  3ICX A;  2ROH A;  4OR0 A;  2XSI A;  4D7X A;  1KDX A;  4K71 A;  4W4U B;  2I2Z A;  2BXE A;  4GDK B;  2EFE A;  1VFI A;  1SB0 A;  1E7I A;  5IIH A;  1IJG A;  3FWC C;  2Z8J A;  2I30 A;  5GHK A;  2DG5 A;  2LOQ A;  4IW1 A;  1MIV A;  4ZBR A;  4DM0 A;  2BXN A;  4N0U D;  1E7H A;  4N3Z A;  3NVK A;  5B5T A;  1O9X A;  3V03 A;  3SIV B;  1MIY A;  2BXD A;  2QMC A;  4IW2 A;  2AGH B;  4G01 A;  1E7E A;  4PO0 A;  1E7B A;  3VQI A;  4OT2 A;  5ID7 A;  2KBZ A;  2AJE A;  4LB2 A;  2BXK A;  2Z8I A;  1BM0 A;  4F5V A;  2QM6 A;  4GDX A;  3WHQ A;  2DBX A;  2LXT A;  2LQI A;  2OT3 A;  4FJC B;  4L8U A;  1N5U A;  2DYO A;  2XW1 A;  4BKE A;  2DBW A;  1AO6 A;  1HA2 A;  3NVM A;  2XVQ A;  2XW0 A;  1LNS A;  2V36 A;  2BXB A;  3MHH B;  3NMU A;  2K0N A;  2BXG A;  4MBE C;  3M99 C;  1BJ5 A;  3SQJ A;  4BY9 C;  2EFC A;  2BXA A;  5IIX A;  3SIU B;  5IJF A;  4HGM B;  1E7F A;  5BPK A;  1LOT A;  4LA0 A;  1E7G A;  5GIO A;  1E78 A;  3WHR A;  1MIW A;  1GNI A;  2XVW A;  5DQF A;  2Z8K A;  5D7G A;  4NAW B;  4LB9 A;  3TDL A;  2BXC A;  4LUF A;  3LU7 A;  4ZBQ A;  4E99 A;  2EFH A;  1FOU A;  2BXH A;  2E0X A;  3H37 A;  5ID9 A;  2YDF A;  5GIN A;  3H3A A;  3GQX A;  4FK5 B;  3A75 A;  2BXQ A;  1HK2 A;  4JK4 A;  2BX8 A;  1HK3 A;  4I9O A;  1JNB A;  3G9K D;  2VUF A;  5HOZ A; 
#chains in the Genus database with same CATH homology
 3MHS B;  2BXF A;  1UOR A;  3B9M A;  5IFO A;  1NT2 B;  4Z9O A;  2BXP A;  3V09 A;  4F5S A;  3B9L A;  2XVU A;  4K2C A;  4F5U A;  1E7A A;  3GQU A;  4S1Y A;  4DHX B;  3LU6 A;  3LU8 A;  4ZCG A;  4HGK A;  2NQO A;  4ZBK A;  2NNW A;  2BXM A;  5IJE A;  4GDL B;  2XVV A;  3FWB C;  1E7C A;  1HK5 A;  1HK4 A;  2VUE A;  3NVI A;  1TXU A;  3JRY A;  3WHS A;  4ZC6 A;  4C31 B;  3GA9 L;  2EFD A;  4LUH A;  4L9Q A;  1J7E A;  3UIV A;  1H9Z A;  4F5T A;  4WA6 B;  4G04 A;  1MA9 A;  1HK1 A;  1TF0 A;  1VZS A;  2VDB A;  2BXL A;  3JQZ A;  1BKE A;  2DBU A;  4M70 B;  5GIP A;  4EMX A;  5FUO A;  2OZB B;  5IJ5 A;  4ZUX V;  5IIU A;  4L9K A;  4TQ1 A;  2CKX A;  2XMO A;  3W1S A;  4Z69 A;  2DYM A;  3V08 A;  2QHB A;  4GG2 A;  3PLA A;  2BXO A;  2JUH A;  3KJL A;  3CX9 A;  4G03 A;  4TQ0 A;  1KXP D;  2BXI A;  1J78 A;  3KIK A;  4J2V A;  1H5W A;  1KW2 A;  4N0F D;  4OTT A;  3A73 A;  3FNM A;  5DBY A;  4OTU A;  4FIP B;  1GNJ A;  2E0Y A;  3ICX A;  2ROH A;  4OR0 A;  2XSI A;  4K71 A;  4W4U B;  2I2Z A;  2BXE A;  4GDK B;  2EFE A;  1VFI A;  1E7I A;  5IIH A;  1IJG A;  3FWC C;  2Z8J A;  2I30 A;  5GHK A;  2DG5 A;  2LOQ A;  4IW1 A;  1MIV A;  4ZBR A;  2BXN A;  4N0U D;  1E7H A;  4N3Z A;  3NVK A;  5B5T A;  1O9X A;  3V03 A;  3SIV B;  1MIY A;  2BXD A;  2QMC A;  4IW2 A;  4G01 A;  1E7E A;  4PO0 A;  1E7B A;  3VQI A;  4OT2 A;  5ID7 A;  2KBZ A;  2AJE A;  4LB2 A;  2BXK A;  2Z8I A;  1BM0 A;  4F5V A;  2QM6 A;  4GDX A;  3WHQ A;  2DBX A;  4FJC B;  2OT3 A;  4L8U A;  1N5U A;  2DYO A;  2XW1 A;  4BKE A;  2DBW A;  1AO6 A;  1HA2 A;  3NVM A;  2XVQ A;  2XW0 A;  1LNS A;  2V36 A;  2BXB A;  3MHH B;  3NMU A;  4MBE C;  2BXG A;  3M99 C;  1BJ5 A;  3SQJ A;  4BY9 C;  2EFC A;  2BXA A;  5IIX A;  3SIU B;  5IJF A;  4HGM B;  1E7F A;  5BPK A;  1LOT A;  4LA0 A;  1E7G A;  5GIO A;  1E78 A;  3WHR A;  1MIW A;  1GNI A;  2XVW A;  5DQF A;  2Z8K A;  5D7G A;  4NAW B;  4LB9 A;  3TDL A;  2BXC A;  4LUF A;  3LU7 A;  4ZBQ A;  4E99 A;  2EFH A;  1FOU A;  2BXH A;  2E0X A;  3H37 A;  5ID9 A;  2YDF A;  5GIN A;  3H3A A;  3GQX A;  4FK5 B;  3A75 A;  2BXQ A;  1HK2 A;  4JK4 A;  2BX8 A;  1HK3 A;  1JNB A;  3G9K D;  2VUF A;  5HOZ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4K71A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations