4LA0A

X-ray study of human serum albumin complexed with bicalutamide
Total Genus 226
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
581
structure length
581
Chain Sequence
AHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural studies of several clinically important oncology drugs in complex with human serum albumin.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords SERUM ALBUMIN
total genus 226
structure length 581
sequence length 581
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A05
2BXBA 5IJFA 5ID7A 1HK4A 2XVWA 4L9KA 3V03A 2I2ZA 4N0UD 4G03A 2BXNA 4ZBRA 4LA0A 1UORA 1BJ5A 3JQZA 4LUFA 1BKEA 3B9MA 1MA9A 1KXPD 2BXFA 4F5UA 4L8UA 2BXQA 2BXLA 5IIXA 4OT2A 2VUFA 4F5TA 4HGKA 5FUOA 4LB9A 3LU7A 1J7EA 4EMXA 5IFOA 3CX9A 1KW2A 1E7IA 4N0FD 2I30A 4BKEA 2XW0A 1GNJA 2VUEA 2VDBA 2XW1A 5IIHA 2BXGA 4OR0A 4F5VA 1E7CA 2YDFA 3TDLA 4Z69A 2BXAA 5ID9A 2BXPA 3A73A 1HA2A 1TF0A 2XVUA 4F5SA 1E7FA 3LU8A 1N5UA 1HK1A 2BXKA 3LU6A 3V09A 1E7BA 1AO6A 4L9QA 2BXEA 4ZBQA 4LUHA 1O9XA 1LOTA 2BXDA 1E7HA 3V08A 3JRYA 4E99A 4S1YA 5GHKA 4IW2A 5IIUA 1E7EA 2BXHA 2XVVA 4K2CA 1E7AA 4JK4A 2BXMA 1E7GA 1HK5A 1HK3A 4HGMB 5HOZA 1H9ZA 3B9LA 5DBYA 2BXOA 4G04A 1J78A 2XVQA 4LB2A 5IJEA 4IW1A 4J2VA 5IJ5A 1E78A 4K71A 3SQJA 4PO0A 1BM0A 2XSIA 5DQFA 3UIVA 2BXCA 2BX8A 1HK2A 1GNIA 2BXIA
chains in the Genus database with same CATH superfamily
4DM0A 2BXBA 5IJFA 5ID7A 2EFCA 4M70B 3H3AA 3VQIA 1HK4A 2DYOA 2XVWA 4L9KA 4FK5B 3WHRA 2OT3A 3V03A 2I2ZA 4N0UD 4G03A 2BXNA 4ZBRA 4LA0A 2LXSA 4GDKB 1UORA 1MIWA 1BJ5A 2E0YA 3JQZA 4LUFA 3GQUA 1BKEA 2ROHA 3B9MA 1MA9A 1KXPD 2BXFA 2KBZA 1H5WA 2LQHA 4F5UA 4C31B 3NMUA 4L8UA 1MIYA 4WA6B 3SIVB 1KDXA 4DHXB 2NQOA 2BXQA 2Z8KA 2BXLA 5IIXA 4OT2A 2AGHB 2VUFA 4HGKA 4F5TA 4ZBKA 2GUTA 5FUOA 2AJEA 4LB9A 1TXUA 4OTUA 3LU7A 4ZC6A 3GA9L 5B5TA 1J7EA 4GDXA 4EMXA 5IFOA 1MUHA 1MUSA 3CX9A 2LOQA 3NVIA 1KW2A 3PLAA 1E7IA 4N0FD 2I30A 1FOUA 2XW0A 4BKEA 3NVKA 2K0NA 1GNJA 2V36A 2VDBA 2VUEA 2XW1A 2EFDA 5IIHA 2DBXA 2BXGA 5BPKA 4OR0A 4F5VA 3BPJA 1E7CA 4D7XA 2YDFA 1MM8A 4NAWB 3TDLA 2Z8JA 3FWCC 4Z69A 2KWFA 1JNBA 4G01A 2BXAA 1VZSA 3FNMA 4MBEC 5ID9A 2BXPA 2EFEA 4GG2A 4OTTA 2E0XA 3A73A 1HA2A 1TF0A 2XVUA 3MHHB 4W4UB 4F5SA 1E7FA 3GQXA 3ECPA 3LU8A 5GIOA 1N5UA 1HK1A 3H37A 2LQIA 4FIPB 3ICXA 4ZCGA 2DBWA 2BXKA 3FWBC 3LU6A 3V09A 1E7BA 1AO6A 4L9QA 3A75A 2BXEA 4N3ZA 5D7GA 5GINA 4ZBQA 3SIUB 3KIKA 4LUHA 1O9XA 1LOTA 1LNSA 2BXDA 3MHSB 2OZBB 1E7HA 2LXTA 3NVMA 4Z9OA 3G9KD 3V08A 2DBUA 3WHSA 3JRYA 3WHQA 4S1YA 5GHKA 4E99A 2NNWA 4IW2A 3KJLA 2QHBA 1NT2B 5IIUA 1E7EA 2BXHA 4BY9C 2XVVA 2QMCA 5GIPA 4K2CA 4TQ1A 1E7AA 4JK4A 3W1SA 2BXMA 1E7GA 1HK5A 2DG5A 1HK3A 4HGMB 5HOZA 1H9ZA 3B9LA 4I9OA 5DBYA 1VFIA 2BXOA 4FJCB 4G04A 2JUHA 1MIVA 1J78A 1SB0A 2XVQA 2XMOA 4LB2A 5IJEA 4IW1A 1IJGA 2CKXA 4J2VA 4TQ0A 5IJ5A 1E78A 4K71A 3M99C 3SQJA 4PO0A 1BM0A 2XSIA 5DQFA 3UIVA 2Z8IA 2BXCA 2EFHA 2BX8A 2QM6A 1HK2A 4ZUXV 2DYMA 1GNIA 4GDLB 2BXIA
chains in the Genus database with same CATH topology
2BXBA 5IJFA 5ID7A 2EFCA 4M70B 3H3AA 3VQIA 1HK4A 2DYOA 2XVWA 4L9KA 4FK5B 3WHRA 2OT3A 3V03A 2I2ZA 4N0UD 4G03A 2BXNA 4ZBRA 4LA0A 4GDKB 1UORA 1MIWA 1BJ5A 2E0YA 3JQZA 4LUFA 3GQUA 1BKEA 2ROHA 3B9MA 1MA9A 1KXPD 2BXFA 2KBZA 1H5WA 4F5UA 4C31B 3NMUA 4L8UA 1MIYA 4WA6B 3SIVB 4DHXB 2NQOA 2BXQA 2Z8KA 2BXLA 5IIXA 4OT2A 2VUFA 4F5TA 4HGKA 4ZBKA 5FUOA 2AJEA 4LB9A 1TXUA 4OTUA 3LU7A 4ZC6A 3GA9L 5B5TA 1J7EA 4GDXA 4EMXA 5IFOA 3CX9A 2LOQA 3NVIA 1KW2A 3PLAA 1E7IA 4N0FD 2I30A 1FOUA 2XW0A 4BKEA 3NVKA 1GNJA 2V36A 2VDBA 2VUEA 2XW1A 2EFDA 5IIHA 2DBXA 2BXGA 5BPKA 4OR0A 4F5VA 1E7CA 2YDFA 4NAWB 3TDLA 2Z8JA 3FWCC 4Z69A 1JNBA 4G01A 2BXAA 1VZSA 3FNMA 4MBEC 5ID9A 2BXPA 2EFEA 4GG2A 4OTTA 2E0XA 3A73A 1HA2A 1TF0A 2XVUA 3MHHB 4W4UB 4F5SA 1E7FA 3GQXA 3LU8A 5GIOA 1N5UA 1HK1A 3H37A 4FIPB 3ICXA 4ZCGA 2DBWA 2BXKA 3FWBC 3LU6A 3V09A 1E7BA 1AO6A 4L9QA 3A75A 2BXEA 4N3ZA 5D7GA 5GINA 4ZBQA 3SIUB 3KIKA 4LUHA 1O9XA 1LOTA 1LNSA 2BXDA 3MHSB 2OZBB 1E7HA 3NVMA 4Z9OA 3G9KD 3V08A 2DBUA 3WHSA 3JRYA 3WHQA 4S1YA 5GHKA 4E99A 2NNWA 4IW2A 3KJLA 2QHBA 1NT2B 5IIUA 1E7EA 2BXHA 4BY9C 2XVVA 2QMCA 5GIPA 4K2CA 4TQ1A 1E7AA 4JK4A 3W1SA 2BXMA 1E7GA 1HK5A 2DG5A 1HK3A 4HGMB 5HOZA 1H9ZA 3B9LA 5DBYA 1VFIA 2BXOA 4FJCB 4G04A 2JUHA 1MIVA 1J78A 2XVQA 2XMOA 4LB2A 5IJEA 4IW1A 1IJGA 2CKXA 4J2VA 4TQ0A 5IJ5A 1E78A 4K71A 3M99C 3SQJA 4PO0A 1BM0A 2XSIA 5DQFA 3UIVA 2Z8IA 2BXCA 2EFHA 2BX8A 2QM6A 1HK2A 4ZUXV 2DYMA 1GNIA 4GDLB 2BXIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXB A;  5IJF A;  5ID7 A;  1HK4 A;  2XVW A;  4L9K A;  3V03 A;  2I2Z A;  4N0U D;  4G03 A;  2BXN A;  4ZBR A;  4LA0 A;  1UOR A;  1BJ5 A;  3JQZ A;  4LUF A;  1BKE A;  3B9M A;  1MA9 A;  1KXP D;  2BXF A;  4F5U A;  4L8U A;  2BXQ A;  2BXL A;  5IIX A;  4OT2 A;  2VUF A;  4F5T A;  4HGK A;  5FUO A;  4LB9 A;  3LU7 A;  1J7E A;  4EMX A;  5IFO A;  3CX9 A;  1KW2 A;  1E7I A;  4N0F D;  2I30 A;  4BKE A;  2XW0 A;  1GNJ A;  2VUE A;  2VDB A;  2XW1 A;  5IIH A;  2BXG A;  4OR0 A;  4F5V A;  1E7C A;  2YDF A;  3TDL A;  4Z69 A;  2BXA A;  5ID9 A;  2BXP A;  3A73 A;  1HA2 A;  1TF0 A;  2XVU A;  4F5S A;  1E7F A;  3LU8 A;  1N5U A;  1HK1 A;  2BXK A;  3LU6 A;  3V09 A;  1E7B A;  1AO6 A;  4L9Q A;  2BXE A;  4ZBQ A;  4LUH A;  1O9X A;  1LOT A;  2BXD A;  1E7H A;  3V08 A;  3JRY A;  4E99 A;  4S1Y A;  5GHK A;  4IW2 A;  5IIU A;  1E7E A;  2BXH A;  2XVV A;  4K2C A;  1E7A A;  4JK4 A;  2BXM A;  1E7G A;  1HK5 A;  1HK3 A;  4HGM B;  5HOZ A;  1H9Z A;  3B9L A;  5DBY A;  2BXO A;  4G04 A;  1J78 A;  2XVQ A;  4LB2 A;  5IJE A;  4IW1 A;  4J2V A;  5IJ5 A;  1E78 A;  4K71 A;  3SQJ A;  4PO0 A;  1BM0 A;  2XSI A;  5DQF A;  3UIV A;  2BXC A;  2BX8 A;  1HK2 A;  1GNI A;  2BXI A; 
#chains in the Genus database with same CATH topology
 4DM0 A;  2BXB A;  5IJF A;  5ID7 A;  2EFC A;  4M70 B;  3H3A A;  3VQI A;  1HK4 A;  2DYO A;  2XVW A;  4L9K A;  4FK5 B;  3WHR A;  2OT3 A;  3V03 A;  2I2Z A;  4N0U D;  4G03 A;  2BXN A;  4ZBR A;  4LA0 A;  2LXS A;  4GDK B;  1UOR A;  1MIW A;  1BJ5 A;  2E0Y A;  3JQZ A;  4LUF A;  3GQU A;  1BKE A;  2ROH A;  3B9M A;  1MA9 A;  1KXP D;  2BXF A;  2KBZ A;  1H5W A;  2LQH A;  4F5U A;  4C31 B;  3NMU A;  4L8U A;  1MIY A;  4WA6 B;  3SIV B;  1KDX A;  4DHX B;  2NQO A;  2BXQ A;  2Z8K A;  2BXL A;  5IIX A;  4OT2 A;  2AGH B;  2VUF A;  4HGK A;  4F5T A;  4ZBK A;  2GUT A;  5FUO A;  2AJE A;  4LB9 A;  1TXU A;  4OTU A;  3LU7 A;  4ZC6 A;  3GA9 L;  5B5T A;  1J7E A;  4GDX A;  4EMX A;  5IFO A;  1MUH A;  1MUS A;  3CX9 A;  2LOQ A;  3NVI A;  1KW2 A;  3PLA A;  1E7I A;  4N0F D;  2I30 A;  1FOU A;  2XW0 A;  4BKE A;  3NVK A;  2K0N A;  1GNJ A;  2V36 A;  2VDB A;  2VUE A;  2XW1 A;  2EFD A;  5IIH A;  2DBX A;  2BXG A;  5BPK A;  4OR0 A;  4F5V A;  3BPJ A;  1E7C A;  4D7X A;  2YDF A;  1MM8 A;  4NAW B;  3TDL A;  2Z8J A;  3FWC C;  4Z69 A;  2KWF A;  1JNB A;  4G01 A;  2BXA A;  1VZS A;  3FNM A;  4MBE C;  5ID9 A;  2BXP A;  2EFE A;  4GG2 A;  4OTT A;  2E0X A;  3A73 A;  1HA2 A;  1TF0 A;  2XVU A;  3MHH B;  4W4U B;  4F5S A;  1E7F A;  3GQX A;  3ECP A;  3LU8 A;  5GIO A;  1N5U A;  1HK1 A;  3H37 A;  2LQI A;  4FIP B;  3ICX A;  4ZCG A;  2DBW A;  2BXK A;  3FWB C;  3LU6 A;  3V09 A;  1E7B A;  1AO6 A;  4L9Q A;  3A75 A;  2BXE A;  4N3Z A;  5D7G A;  5GIN A;  4ZBQ A;  3SIU B;  3KIK A;  4LUH A;  1O9X A;  1LOT A;  1LNS A;  2BXD A;  3MHS B;  2OZB B;  1E7H A;  2LXT A;  3NVM A;  4Z9O A;  3G9K D;  3V08 A;  2DBU A;  3WHS A;  3JRY A;  3WHQ A;  4S1Y A;  5GHK A;  4E99 A;  2NNW A;  4IW2 A;  3KJL A;  2QHB A;  1NT2 B;  5IIU A;  1E7E A;  2BXH A;  4BY9 C;  2XVV A;  2QMC A;  5GIP A;  4K2C A;  4TQ1 A;  1E7A A;  4JK4 A;  3W1S A;  2BXM A;  1E7G A;  1HK5 A;  2DG5 A;  1HK3 A;  4HGM B;  5HOZ A;  1H9Z A;  3B9L A;  4I9O A;  5DBY A;  1VFI A;  2BXO A;  4FJC B;  4G04 A;  2JUH A;  1MIV A;  1J78 A;  1SB0 A;  2XVQ A;  2XMO A;  4LB2 A;  5IJE A;  4IW1 A;  1IJG A;  2CKX A;  4J2V A;  4TQ0 A;  5IJ5 A;  1E78 A;  4K71 A;  3M99 C;  3SQJ A;  4PO0 A;  1BM0 A;  2XSI A;  5DQF A;  3UIV A;  2Z8I A;  2BXC A;  2EFH A;  2BX8 A;  2QM6 A;  1HK2 A;  4ZUX V;  2DYM A;  1GNI A;  4GDL B;  2BXI A; 
#chains in the Genus database with same CATH homology
 2BXB A;  5IJF A;  5ID7 A;  2EFC A;  4M70 B;  3H3A A;  3VQI A;  1HK4 A;  2DYO A;  2XVW A;  4L9K A;  4FK5 B;  3WHR A;  2OT3 A;  3V03 A;  2I2Z A;  4N0U D;  4G03 A;  2BXN A;  4ZBR A;  4LA0 A;  4GDK B;  1UOR A;  1MIW A;  1BJ5 A;  2E0Y A;  3JQZ A;  4LUF A;  3GQU A;  1BKE A;  2ROH A;  3B9M A;  1MA9 A;  1KXP D;  2BXF A;  2KBZ A;  1H5W A;  4F5U A;  4C31 B;  3NMU A;  4L8U A;  1MIY A;  4WA6 B;  3SIV B;  4DHX B;  2NQO A;  2BXQ A;  2Z8K A;  2BXL A;  5IIX A;  4OT2 A;  2VUF A;  4F5T A;  4HGK A;  4ZBK A;  5FUO A;  2AJE A;  4LB9 A;  1TXU A;  4OTU A;  3LU7 A;  4ZC6 A;  3GA9 L;  5B5T A;  1J7E A;  4GDX A;  4EMX A;  5IFO A;  3CX9 A;  2LOQ A;  3NVI A;  1KW2 A;  3PLA A;  1E7I A;  4N0F D;  2I30 A;  1FOU A;  2XW0 A;  4BKE A;  3NVK A;  1GNJ A;  2V36 A;  2VDB A;  2VUE A;  2XW1 A;  2EFD A;  5IIH A;  2DBX A;  2BXG A;  5BPK A;  4OR0 A;  4F5V A;  1E7C A;  2YDF A;  4NAW B;  3TDL A;  2Z8J A;  3FWC C;  4Z69 A;  1JNB A;  4G01 A;  2BXA A;  1VZS A;  3FNM A;  4MBE C;  5ID9 A;  2BXP A;  2EFE A;  4GG2 A;  4OTT A;  2E0X A;  3A73 A;  1HA2 A;  1TF0 A;  2XVU A;  3MHH B;  4W4U B;  4F5S A;  1E7F A;  3GQX A;  3LU8 A;  5GIO A;  1N5U A;  1HK1 A;  3H37 A;  4FIP B;  3ICX A;  4ZCG A;  2DBW A;  2BXK A;  3FWB C;  3LU6 A;  3V09 A;  1E7B A;  1AO6 A;  4L9Q A;  3A75 A;  2BXE A;  4N3Z A;  5D7G A;  5GIN A;  4ZBQ A;  3SIU B;  3KIK A;  4LUH A;  1O9X A;  1LOT A;  1LNS A;  2BXD A;  3MHS B;  2OZB B;  1E7H A;  3NVM A;  4Z9O A;  3G9K D;  3V08 A;  2DBU A;  3WHS A;  3JRY A;  3WHQ A;  4S1Y A;  5GHK A;  4E99 A;  2NNW A;  4IW2 A;  3KJL A;  2QHB A;  1NT2 B;  5IIU A;  1E7E A;  2BXH A;  4BY9 C;  2XVV A;  2QMC A;  5GIP A;  4K2C A;  4TQ1 A;  1E7A A;  4JK4 A;  3W1S A;  2BXM A;  1E7G A;  1HK5 A;  2DG5 A;  1HK3 A;  4HGM B;  5HOZ A;  1H9Z A;  3B9L A;  5DBY A;  1VFI A;  2BXO A;  4FJC B;  4G04 A;  2JUH A;  1MIV A;  1J78 A;  2XVQ A;  2XMO A;  4LB2 A;  5IJE A;  4IW1 A;  1IJG A;  2CKX A;  4J2V A;  4TQ0 A;  5IJ5 A;  1E78 A;  4K71 A;  3M99 C;  3SQJ A;  4PO0 A;  1BM0 A;  2XSI A;  5DQF A;  3UIV A;  2Z8I A;  2BXC A;  2EFH A;  2BX8 A;  2QM6 A;  1HK2 A;  4ZUX V;  2DYM A;  1GNI A;  4GDL B;  2BXI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...