4N0FD

Human fcrn complexed with human serum albumin
Total Genus 223
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
223
sequence length
583
structure length
583
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms.
pubmed doi rcsb
molecule tags Immune system
molecule keywords IgG receptor FcRn large subunit p51
total genus 223
structure length 583
sequence length 583
chains with identical sequence G, J, M
ec nomenclature
pdb deposition date 2013-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD05
4LB9A 2XVUA 2BXBA 2VUFA 5HOZA 2BXIA 5ID7A 1BJ5A 1BM0A 3LU8A 3UIVA 4ZBRA 3TDLA 1O9XA 4J2VA 3JRYA 5IIXA 1E7HA 2BXEA 1TF0A 4N0FD 5ID9A 1E7IA 5IIUA 1E7GA 3V09A 1E78A 1E7CA 4Z69A 2XVWA 5DQFA 1E7EA 4LA0A 4BKEA 4OT2A 2BXFA 1BKEA 4K2CA 2BXDA 4N0UD 1GNJA 1E7BA 3LU7A 4F5VA 1N5UA 4S1YA 2VUEA 1H9ZA 2XW0A 2BXCA 4HGMB 4EMXA 5IIHA 4ZBQA 2BX8A 3B9MA 5FUOA 4F5SA 2BXNA 5IJEA 1J7EA 4IW2A 2XVQA 2BXAA 2I30A 2XSIA 2YDFA 1E7AA 1HK4A 4OR0A 1MA9A 1UORA 2BXGA 5DBYA 1E7FA 2BXKA 2BXOA 3V03A 4K71A 1KW2A 4LB2A 5IJFA 5IJ5A 1HA2A 3A73A 4HGKA 2BXMA 4LUFA 5IFOA 1AO6A 4G03A 4L8UA 1GNIA 1HK3A 1HK2A 2BXQA 1HK5A 4E99A 4F5UA 2XW1A 2BXLA 4JK4A 2I2ZA 1J78A 4PO0A 1KXPD 2VDBA 4IW1A 2BXPA 3LU6A 3CX9A 2BXHA 4L9KA 4L9QA 3JQZA 2XVVA 3SQJA 4F5TA 1LOTA 3B9LA 4LUHA 4G04A 5GHKA 3V08A 1HK1A
chains in the Genus database with same CATH superfamily
4LB9A 2XVUA 2DBWA 2GUTA 2BXBA 2VUFA 3A75A 4BY9C 2ROHA 2NNWA 5HOZA 2BXIA 4FIPB 1BJ5A 4ZC6A 5ID7A 2DBXA 3WHQA 1KDXA 4OTTA 4TQ1A 3ECPA 1BM0A 3LU8A 3UIVA 4ZBRA 3TDLA 2LOQA 1O9XA 1VZSA 4J2VA 4M70B 1MM8A 1TXUA 3JRYA 2AGHB 5IIXA 1E7HA 1JNBA 1TF0A 2BXEA 4N0FD 5ID9A 1NT2B 2DG5A 1E7IA 5IIUA 1E7GA 3V09A 1E78A 1E7CA 2Z8IA 4Z69A 2XVWA 4C31B 5DQFA 1E7EA 3MHSB 3W1SA 4D7XA 2JUHA 5GIPA 4LA0A 4BKEA 4OT2A 1MIYA 2BXFA 4DM0A 1BKEA 4K2CA 2BXDA 4N0UD 5D7GA 1GNJA 3H3AA 1E7BA 3LU7A 4F5VA 3FNMA 1N5UA 3WHRA 4S1YA 2VUEA 1H9ZA 2XW0A 1VFIA 3WHSA 2BXCA 3ICXA 4HGMB 4NAWB 4Z9OA 4EMXA 2Z8KA 2QM6A 5IIHA 4GDLB 2DBUA 2BX8A 2CKXA 3B9MA 4ZBQA 5FUOA 4F5SA 2E0YA 2LXTA 2BXNA 5IJEA 1J7EA 4FJCB 2EFEA 2EFHA 1SB0A 3FWCC 2XVQA 4IW2A 2BXAA 4MBEC 1MIWA 2I30A 3SIVB 2XSIA 2YDFA 5B5TA 4N3ZA 2AJEA 2K0NA 1E7AA 1HK4A 3KJLA 4OR0A 4W4UB 1IJGA 3VQIA 1MA9A 1LNSA 1UORA 2BXGA 5DBYA 1E7FA 2BXKA 2BXOA 3V03A 3NVMA 4K71A 4WA6B 1KW2A 4LB2A 4DHXB 4G01A 5IJFA 4ZCGA 5IJ5A 3GA9L 3NVKA 1HA2A 3A73A 4HGKA 2V36A 4ZUXV 2BXMA 2DYOA 2Z8JA 2QMCA 4LUFA 5IFOA 1AO6A 1MIVA 4GG2A 4G03A 1MUHA 4L8UA 2OZBB 1GNIA 2EFCA 1HK3A 1HK2A 2BXQA 1HK5A 2EFDA 3BPJA 4E99A 4F5UA 2XW1A 2BXLA 1FOUA 3H37A 4JK4A 2LQHA 1MUSA 4ZBKA 2I2ZA 3KIKA 2OT3A 2LQIA 4FK5B 1J78A 4PO0A 4GDXA 2QHBA 1KXPD 2VDBA 3FWBC 2XMOA 4OTUA 4IW1A 3SIUB 2BXPA 2KBZA 3LU6A 4GDKB 3M99C 3CX9A 3NVIA 2BXHA 4L9KA 2LXSA 2NQOA 2DYMA 4TQ0A 4L9QA 3GQUA 3JQZA 4I9OA 5BPKA 2XVVA 3MHHB 3SQJA 4F5TA 1LOTA 2E0XA 3G9KD 3GQXA 2KWFA 3B9LA 4G04A 4LUHA 5GHKA 5GINA 3NMUA 3V08A 3PLAA 5GIOA 1H5WA 1HK1A
chains in the Genus database with same CATH topology
4LB9A 2XVUA 2DBWA 2BXBA 2VUFA 3A75A 4BY9C 2ROHA 2NNWA 5HOZA 2BXIA 4FIPB 1BJ5A 4ZC6A 5ID7A 2DBXA 3WHQA 4OTTA 4TQ1A 1BM0A 3LU8A 3UIVA 4ZBRA 3TDLA 2LOQA 1O9XA 1VZSA 4J2VA 4M70B 1TXUA 3JRYA 5IIXA 1E7HA 1JNBA 1TF0A 2BXEA 4N0FD 5ID9A 1NT2B 2DG5A 1E7IA 5IIUA 1E7GA 3V09A 1E78A 1E7CA 2Z8IA 4Z69A 2XVWA 4C31B 5DQFA 1E7EA 3MHSB 3W1SA 2JUHA 5GIPA 4LA0A 4BKEA 4OT2A 1MIYA 2BXFA 1BKEA 4K2CA 2BXDA 4N0UD 5D7GA 1GNJA 3H3AA 1E7BA 3LU7A 4F5VA 3FNMA 1N5UA 3WHRA 4S1YA 2VUEA 1H9ZA 2XW0A 1VFIA 3WHSA 2BXCA 3ICXA 4HGMB 4NAWB 4Z9OA 4EMXA 2Z8KA 2QM6A 5IIHA 4GDLB 2DBUA 2BX8A 2CKXA 3B9MA 4ZBQA 5FUOA 4F5SA 2E0YA 2BXNA 5IJEA 1J7EA 4FJCB 2EFEA 2EFHA 3FWCC 4IW2A 2XVQA 2BXAA 4MBEC 1MIWA 2I30A 3SIVB 2XSIA 2YDFA 5B5TA 4N3ZA 2AJEA 1E7AA 1HK4A 3KJLA 4OR0A 4W4UB 1IJGA 3VQIA 1MA9A 1LNSA 1UORA 2BXGA 5DBYA 1E7FA 2BXKA 2BXOA 3V03A 3NVMA 4K71A 4WA6B 1KW2A 4LB2A 4DHXB 4G01A 5IJFA 4ZCGA 5IJ5A 3GA9L 3NVKA 1HA2A 3A73A 4HGKA 2V36A 4ZUXV 2BXMA 2DYOA 2Z8JA 2QMCA 4LUFA 5IFOA 1AO6A 1MIVA 4GG2A 4G03A 4L8UA 2OZBB 1GNIA 2EFCA 1HK3A 1HK2A 2BXQA 1HK5A 2EFDA 4E99A 4F5UA 2XW1A 2BXLA 1FOUA 3H37A 4JK4A 4ZBKA 2I2ZA 3KIKA 2OT3A 4FK5B 1J78A 4PO0A 4GDXA 2QHBA 1KXPD 2VDBA 3FWBC 2XMOA 4OTUA 4IW1A 3SIUB 2BXPA 2KBZA 3LU6A 4GDKB 3M99C 3CX9A 3NVIA 2BXHA 4L9KA 2NQOA 2DYMA 4TQ0A 4L9QA 3GQUA 3JQZA 5BPKA 2XVVA 3MHHB 3SQJA 4F5TA 1LOTA 2E0XA 3G9KD 3GQXA 3B9LA 4LUHA 4G04A 5GHKA 5GINA 3NMUA 3V08A 3PLAA 5GIOA 1H5WA 1HK1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LB9 A;  2XVU A;  2BXB A;  2VUF A;  5HOZ A;  2BXI A;  5ID7 A;  1BJ5 A;  1BM0 A;  3LU8 A;  3UIV A;  4ZBR A;  3TDL A;  1O9X A;  4J2V A;  3JRY A;  5IIX A;  1E7H A;  2BXE A;  1TF0 A;  4N0F D;  5ID9 A;  1E7I A;  5IIU A;  1E7G A;  3V09 A;  1E78 A;  1E7C A;  4Z69 A;  2XVW A;  5DQF A;  1E7E A;  4LA0 A;  4BKE A;  4OT2 A;  2BXF A;  1BKE A;  4K2C A;  2BXD A;  4N0U D;  1GNJ A;  1E7B A;  3LU7 A;  4F5V A;  1N5U A;  4S1Y A;  2VUE A;  1H9Z A;  2XW0 A;  2BXC A;  4HGM B;  4EMX A;  5IIH A;  4ZBQ A;  2BX8 A;  3B9M A;  5FUO A;  4F5S A;  2BXN A;  5IJE A;  1J7E A;  4IW2 A;  2XVQ A;  2BXA A;  2I30 A;  2XSI A;  2YDF A;  1E7A A;  1HK4 A;  4OR0 A;  1MA9 A;  1UOR A;  2BXG A;  5DBY A;  1E7F A;  2BXK A;  2BXO A;  3V03 A;  4K71 A;  1KW2 A;  4LB2 A;  5IJF A;  5IJ5 A;  1HA2 A;  3A73 A;  4HGK A;  2BXM A;  4LUF A;  5IFO A;  1AO6 A;  4G03 A;  4L8U A;  1GNI A;  1HK3 A;  1HK2 A;  2BXQ A;  1HK5 A;  4E99 A;  4F5U A;  2XW1 A;  2BXL A;  4JK4 A;  2I2Z A;  1J78 A;  4PO0 A;  1KXP D;  2VDB A;  4IW1 A;  2BXP A;  3LU6 A;  3CX9 A;  2BXH A;  4L9K A;  4L9Q A;  3JQZ A;  2XVV A;  3SQJ A;  4F5T A;  1LOT A;  3B9L A;  4LUH A;  4G04 A;  5GHK A;  3V08 A;  1HK1 A; 
#chains in the Genus database with same CATH topology
 4LB9 A;  2XVU A;  2DBW A;  2GUT A;  2BXB A;  2VUF A;  3A75 A;  4BY9 C;  2ROH A;  2NNW A;  5HOZ A;  2BXI A;  4FIP B;  1BJ5 A;  4ZC6 A;  5ID7 A;  2DBX A;  3WHQ A;  1KDX A;  4OTT A;  4TQ1 A;  3ECP A;  1BM0 A;  3LU8 A;  3UIV A;  4ZBR A;  3TDL A;  2LOQ A;  1O9X A;  1VZS A;  4J2V A;  4M70 B;  1MM8 A;  1TXU A;  3JRY A;  2AGH B;  5IIX A;  1E7H A;  1JNB A;  1TF0 A;  2BXE A;  4N0F D;  5ID9 A;  1NT2 B;  2DG5 A;  1E7I A;  5IIU A;  1E7G A;  3V09 A;  1E78 A;  1E7C A;  2Z8I A;  4Z69 A;  2XVW A;  4C31 B;  5DQF A;  1E7E A;  3MHS B;  3W1S A;  4D7X A;  2JUH A;  5GIP A;  4LA0 A;  4BKE A;  4OT2 A;  1MIY A;  2BXF A;  4DM0 A;  1BKE A;  4K2C A;  2BXD A;  4N0U D;  5D7G A;  1GNJ A;  3H3A A;  1E7B A;  3LU7 A;  4F5V A;  3FNM A;  1N5U A;  3WHR A;  4S1Y A;  2VUE A;  1H9Z A;  2XW0 A;  1VFI A;  3WHS A;  2BXC A;  3ICX A;  4HGM B;  4NAW B;  4Z9O A;  4EMX A;  2Z8K A;  2QM6 A;  5IIH A;  4GDL B;  2DBU A;  2BX8 A;  2CKX A;  3B9M A;  4ZBQ A;  5FUO A;  4F5S A;  2E0Y A;  2LXT A;  2BXN A;  5IJE A;  1J7E A;  4FJC B;  2EFE A;  2EFH A;  1SB0 A;  3FWC C;  2XVQ A;  4IW2 A;  2BXA A;  4MBE C;  1MIW A;  2I30 A;  3SIV B;  2XSI A;  2YDF A;  5B5T A;  4N3Z A;  2AJE A;  2K0N A;  1E7A A;  1HK4 A;  3KJL A;  4OR0 A;  4W4U B;  1IJG A;  3VQI A;  1MA9 A;  1LNS A;  1UOR A;  2BXG A;  5DBY A;  1E7F A;  2BXK A;  2BXO A;  3V03 A;  3NVM A;  4K71 A;  4WA6 B;  1KW2 A;  4LB2 A;  4DHX B;  4G01 A;  5IJF A;  4ZCG A;  5IJ5 A;  3GA9 L;  3NVK A;  1HA2 A;  3A73 A;  4HGK A;  2V36 A;  4ZUX V;  2BXM A;  2DYO A;  2Z8J A;  2QMC A;  4LUF A;  5IFO A;  1AO6 A;  1MIV A;  4GG2 A;  4G03 A;  1MUH A;  4L8U A;  2OZB B;  1GNI A;  2EFC A;  1HK3 A;  1HK2 A;  2BXQ A;  1HK5 A;  2EFD A;  3BPJ A;  4E99 A;  4F5U A;  2XW1 A;  2BXL A;  1FOU A;  3H37 A;  4JK4 A;  2LQH A;  1MUS A;  4ZBK A;  2I2Z A;  3KIK A;  2OT3 A;  2LQI A;  4FK5 B;  1J78 A;  4PO0 A;  4GDX A;  2QHB A;  1KXP D;  2VDB A;  3FWB C;  2XMO A;  4OTU A;  4IW1 A;  3SIU B;  2BXP A;  2KBZ A;  3LU6 A;  4GDK B;  3M99 C;  3CX9 A;  3NVI A;  2BXH A;  4L9K A;  2LXS A;  2NQO A;  2DYM A;  4TQ0 A;  4L9Q A;  3GQU A;  3JQZ A;  4I9O A;  5BPK A;  2XVV A;  3MHH B;  3SQJ A;  4F5T A;  1LOT A;  2E0X A;  3G9K D;  3GQX A;  2KWF A;  3B9L A;  4G04 A;  4LUH A;  5GHK A;  5GIN A;  3NMU A;  3V08 A;  3PLA A;  5GIO A;  1H5W A;  1HK1 A; 
#chains in the Genus database with same CATH homology
 4LB9 A;  2XVU A;  2DBW A;  2BXB A;  2VUF A;  3A75 A;  4BY9 C;  2ROH A;  2NNW A;  5HOZ A;  2BXI A;  4FIP B;  1BJ5 A;  4ZC6 A;  5ID7 A;  2DBX A;  3WHQ A;  4OTT A;  4TQ1 A;  1BM0 A;  3LU8 A;  3UIV A;  4ZBR A;  3TDL A;  2LOQ A;  1O9X A;  1VZS A;  4J2V A;  4M70 B;  1TXU A;  3JRY A;  5IIX A;  1E7H A;  1JNB A;  1TF0 A;  2BXE A;  4N0F D;  5ID9 A;  1NT2 B;  2DG5 A;  1E7I A;  5IIU A;  1E7G A;  3V09 A;  1E78 A;  1E7C A;  2Z8I A;  4Z69 A;  2XVW A;  4C31 B;  5DQF A;  1E7E A;  3MHS B;  3W1S A;  2JUH A;  5GIP A;  4LA0 A;  4BKE A;  4OT2 A;  1MIY A;  2BXF A;  1BKE A;  4K2C A;  2BXD A;  4N0U D;  5D7G A;  1GNJ A;  3H3A A;  1E7B A;  3LU7 A;  4F5V A;  3FNM A;  1N5U A;  3WHR A;  4S1Y A;  2VUE A;  1H9Z A;  2XW0 A;  1VFI A;  3WHS A;  2BXC A;  3ICX A;  4HGM B;  4NAW B;  4Z9O A;  4EMX A;  2Z8K A;  2QM6 A;  5IIH A;  4GDL B;  2DBU A;  2BX8 A;  2CKX A;  3B9M A;  4ZBQ A;  5FUO A;  4F5S A;  2E0Y A;  2BXN A;  5IJE A;  1J7E A;  4FJC B;  2EFE A;  2EFH A;  3FWC C;  4IW2 A;  2XVQ A;  2BXA A;  4MBE C;  1MIW A;  2I30 A;  3SIV B;  2XSI A;  2YDF A;  5B5T A;  4N3Z A;  2AJE A;  1E7A A;  1HK4 A;  3KJL A;  4OR0 A;  4W4U B;  1IJG A;  3VQI A;  1MA9 A;  1LNS A;  1UOR A;  2BXG A;  5DBY A;  1E7F A;  2BXK A;  2BXO A;  3V03 A;  3NVM A;  4K71 A;  4WA6 B;  1KW2 A;  4LB2 A;  4DHX B;  4G01 A;  5IJF A;  4ZCG A;  5IJ5 A;  3GA9 L;  3NVK A;  1HA2 A;  3A73 A;  4HGK A;  2V36 A;  4ZUX V;  2BXM A;  2DYO A;  2Z8J A;  2QMC A;  4LUF A;  5IFO A;  1AO6 A;  1MIV A;  4GG2 A;  4G03 A;  4L8U A;  2OZB B;  1GNI A;  2EFC A;  1HK3 A;  1HK2 A;  2BXQ A;  1HK5 A;  2EFD A;  4E99 A;  4F5U A;  2XW1 A;  2BXL A;  1FOU A;  3H37 A;  4JK4 A;  4ZBK A;  2I2Z A;  3KIK A;  2OT3 A;  4FK5 B;  1J78 A;  4PO0 A;  4GDX A;  2QHB A;  1KXP D;  2VDB A;  3FWB C;  2XMO A;  4OTU A;  4IW1 A;  3SIU B;  2BXP A;  2KBZ A;  3LU6 A;  4GDK B;  3M99 C;  3CX9 A;  3NVI A;  2BXH A;  4L9K A;  2NQO A;  2DYM A;  4TQ0 A;  4L9Q A;  3GQU A;  3JQZ A;  5BPK A;  2XVV A;  3MHH B;  3SQJ A;  4F5T A;  1LOT A;  2E0X A;  3G9K D;  3GQX A;  3B9L A;  4LUH A;  4G04 A;  5GHK A;  5GIN A;  3NMU A;  3V08 A;  3PLA A;  5GIO A;  1H5W A;  1HK1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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