4N0U | Genus

Total Genus 219

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	219
sequence length	583
structure length	583
Chain Sequence	HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms. pubmed doi rcsb
molecule keywords	IgG receptor FcRn large subunit p51
molecule tags	Dna binding protein
source organism	Homo sapiens
total genus	219
structure length	583
sequence length	583
ec nomenclature
pdb deposition date	2013-10-02

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
D	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4n0uD03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4n0uD02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4n0uD04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4n0uD01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4n0uD06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	4n0uD05

2BX8A 4JK4A 1H9ZA 1GNJA 5IJFA 2BXEA 2BXAA 1AO6A 2I30A 3A73A 3LU8A 2XSIA 5IFOA 5ID9A 1BM0A 5IJEA 3LU7A 2BXLA 1MA9A 1J78A 2XVQA 2XVUA 4HGKA 1J7EA 4PO0A 4F5TA 3JQZA 4J2VA 1UORA 4LB9A 3V03A 4G03A 4L9KA 1E7HA 2VUFA 3B9MA 1E7GA 2XVVA 2XW1A 2BXGA 4ZBRA 2BXQA 5IJ5A 2BXMA 1O9XA 3V08A 3UIVA 1N5UA 2YDFA 1BJ5A 3JRYA 3CX9A 4N0UD 4K2CA 4LUHA 2BXBA 4IW2A 4LUFA 1E7FA 2BXPA 4E99A 4K71A 2BXKA 2BXFA 4LB2A 4F5SA 1TF0A 4N0FD 4OR0A 4G04A 1KW2A 4HGMB 1E7IA 4Z69A 5IIXA 4LA0A 3SQJA 2BXDA 5DBYA 2BXIA 2XW0A 4ZBQA 4BKEA 2I2ZA 2BXNA 4EMXA 1LOTA 2XVWA 3V09A 2VUEA 2BXHA 5IIHA 1E7CA 1HK1A 3TDLA 1BKEA 4IW1A 4F5VA 1HK2A 1HK5A 1GNIA 3LU6A 2BXOA 4S1YA 1E7AA 2BXCA 2VDBA 5GHKA 1KXPD 5HOZA 1HK3A 5DQFA 5FUOA 1E78A 1HA2A 4L8UA 4OT2A 5IIUA 1E7BA 1E7EA 3B9LA 5ID7A 4F5UA 1HK4A 4L9QA
chains in the Genus database with same CATH superfamily

2BX8A 4JK4A 1H9ZA 1GNJA 4G01A 1VFIA 5IJFA 2BXEA 4TQ0A 1FOUA 2BXAA 1AO6A 1MIYA 2I30A 2AGHB 3A73A 3LU8A 2XSIA 3FWBC 4N3ZA 2Z8JA 5IFOA 5ID9A 4DM0A 1BM0A 2NNWA 2EFEA 5IJEA 3LU7A 2BXLA 3NVMA 1MA9A 1J78A 2XVQA 2QM6A 2XVUA 1J7EA 2V36A 2Z8IA 3FWCC 3JQZA 4HGKA 4PO0A 4F5TA 4J2VA 1UORA 2CKXA 4LB9A 3FNMA 3KJLA 3V03A 4G03A 4L9KA 4M70B 1E7HA 2VUFA 1SB0A 4GDXA 2OT3A 1MIWA 3B9MA 3GQUA 1E7GA 2XVVA 1LNSA 1H5WA 2XW1A 4Z9OA 2BXGA 4TQ1A 4ZBRA 2BXQA 5IJ5A 2BXMA 2OZBB 2DYOA 4NAWB 1O9XA 1TXUA 3V08A 3UIVA 2EFCA 3WHQA 1N5UA 3A75A 2DBWA 2GUTA 2XMOA 2YDFA 1BJ5A 3MHSB 4GDKB 3JRYA 3CX9A 3MHHB 2ROHA 4N0UD 3BPJA 4K2CA 3WHRA 3KIKA 4LUHA 2E0XA 2BXBA 4MBEC 4I9OA 4IW2A 4LUFA 1E7FA 2BXPA 2DBUA 4E99A 4K71A 5BPKA 2BXKA 1MUSA 2LXSA 2BXFA 4BY9C 2EFHA 4LB2A 4W4UB 4F5SA 1TF0A 4N0FD 4OR0A 4G04A 3NVIA 1KW2A 4HGMB 1E7IA 4ZC6A 4Z69A 3ECPA 2LQHA 5IIXA 4LA0A 4D7XA 4ZCGA 5B5TA 3SQJA 2AJEA 4ZBKA 5GINA 1MUHA 2BXDA 4GG2A 1JNBA 2LXTA 5DBYA 3H3AA 2BXIA 3SIUB 2DBXA 2KWFA 2XW0A 4FK5B 4ZBQA 4BKEA 2E0YA 2I2ZA 2BXNA 2QMCA 3H37A 3VQIA 2EFDA 4EMXA 4FJCB 2QHBA 3M99C 1LOTA 2XVWA 3V09A 4GDLB 4DHXB 2LQIA 2VUEA 2BXHA 5IIHA 1E7CA 1HK1A 4WA6B 3WHSA 2DYMA 3TDLA 1BKEA 2KBZA 4IW1A 4F5VA 1NT2B 1HK2A 1HK5A 1GNIA 3LU6A 2BXOA 5D7GA 4S1YA 1E7AA 3W1SA 2BXCA 4ZUXV 2VDBA 2Z8KA 5GHKA 1KXPD 3SIVB 2DG5A 4OTTA 5HOZA 1HK3A 2JUHA 5GIOA 5DQFA 1MM8A 5FUOA 1IJGA 1E78A 1HA2A 3GQXA 4L8UA 1KDXA 3ICXA 1VZSA 2LOQA 4OT2A 3NMUA 5IIUA 4OTUA 3PLAA 4C31B 1E7BA 1E7EA 4FIPB 3G9KD 3GA9L 3B9LA 5GIPA 1MIVA 5ID7A 4F5UA 2K0NA 3NVKA 1HK4A 4L9QA 2NQOA
chains in the Genus database with same CATH topology

2BX8A 4JK4A 1H9ZA 1GNJA 4G01A 1VFIA 5IJFA 2BXEA 4TQ0A 1FOUA 2BXAA 1AO6A 1MIYA 2I30A 3A73A 3LU8A 2XSIA 3FWBC 4N3ZA 2Z8JA 5IFOA 5ID9A 1BM0A 2NNWA 2EFEA 5IJEA 3LU7A 2BXLA 3NVMA 1MA9A 1J78A 2XVQA 2QM6A 2XVUA 1J7EA 2V36A 2Z8IA 3FWCC 3JQZA 4HGKA 4PO0A 4F5TA 4J2VA 1UORA 2CKXA 4LB9A 3FNMA 3KJLA 3V03A 4G03A 4L9KA 4M70B 1E7HA 2VUFA 4GDXA 2OT3A 1MIWA 3B9MA 3GQUA 1E7GA 2XVVA 1LNSA 1H5WA 2XW1A 4Z9OA 2BXGA 4TQ1A 4ZBRA 2BXQA 5IJ5A 2BXMA 2OZBB 2DYOA 4NAWB 1O9XA 1TXUA 3V08A 3UIVA 2EFCA 3WHQA 1N5UA 3A75A 2DBWA 2XMOA 2YDFA 1BJ5A 3MHSB 4GDKB 3JRYA 3CX9A 3MHHB 2ROHA 4N0UD 4K2CA 3WHRA 3KIKA 4LUHA 2E0XA 2BXBA 4MBEC 4IW2A 4LUFA 1E7FA 2BXPA 2DBUA 4E99A 4K71A 5BPKA 2BXKA 2BXFA 4BY9C 2EFHA 4LB2A 4W4UB 4F5SA 1TF0A 4N0FD 4OR0A 4G04A 3NVIA 1KW2A 4HGMB 1E7IA 4ZC6A 4Z69A 5IIXA 4LA0A 4ZCGA 5B5TA 3SQJA 2AJEA 4ZBKA 5GINA 2BXDA 4GG2A 1JNBA 5DBYA 3H3AA 2BXIA 3SIUB 2DBXA 2XW0A 4FK5B 4ZBQA 4BKEA 2E0YA 2I2ZA 2BXNA 2QMCA 3H37A 3VQIA 2EFDA 4EMXA 4FJCB 2QHBA 3M99C 1LOTA 2XVWA 3V09A 4GDLB 4DHXB 2VUEA 2BXHA 5IIHA 1E7CA 1HK1A 4WA6B 3WHSA 2DYMA 3TDLA 1BKEA 2KBZA 4IW1A 4F5VA 1NT2B 1HK2A 1HK5A 1GNIA 3LU6A 2BXOA 5D7GA 4S1YA 1E7AA 3W1SA 2BXCA 4ZUXV 2VDBA 2Z8KA 5GHKA 1KXPD 3SIVB 2DG5A 4OTTA 5HOZA 1HK3A 2JUHA 5GIOA 5DQFA 5FUOA 1IJGA 1E78A 1HA2A 3GQXA 4L8UA 3ICXA 1VZSA 2LOQA 4OT2A 3NMUA 5IIUA 4OTUA 3PLAA 4C31B 1E7BA 1E7EA 4FIPB 3G9KD 3GA9L 3B9LA 5GIPA 1MIVA 5ID7A 4F5UA 3NVKA 1HK4A 4L9QA 2NQOA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2BX8 A;  4JK4 A;  1H9Z A;  1GNJ A;  5IJF A;  2BXE A;  2BXA A;  1AO6 A;  2I30 A;  3A73 A;  3LU8 A;  2XSI A;  5IFO A;  5ID9 A;  1BM0 A;  5IJE A;  3LU7 A;  2BXL A;  1MA9 A;  1J78 A;  2XVQ A;  2XVU A;  4HGK A;  1J7E A;  4PO0 A;  4F5T A;  3JQZ A;  4J2V A;  1UOR A;  4LB9 A;  3V03 A;  4G03 A;  4L9K A;  1E7H A;  2VUF A;  3B9M A;  1E7G A;  2XVV A;  2XW1 A;  2BXG A;  4ZBR A;  2BXQ A;  5IJ5 A;  2BXM A;  1O9X A;  3V08 A;  3UIV A;  1N5U A;  2YDF A;  1BJ5 A;  3JRY A;  3CX9 A;  4N0U D;  4K2C A;  4LUH A;  2BXB A;  4IW2 A;  4LUF A;  1E7F A;  2BXP A;  4E99 A;  4K71 A;  2BXK A;  2BXF A;  4LB2 A;  4F5S A;  1TF0 A;  4N0F D;  4OR0 A;  4G04 A;  1KW2 A;  4HGM B;  1E7I A;  4Z69 A;  5IIX A;  4LA0 A;  3SQJ A;  2BXD A;  5DBY A;  2BXI A;  2XW0 A;  4ZBQ A;  4BKE A;  2I2Z A;  2BXN A;  4EMX A;  1LOT A;  2XVW A;  3V09 A;  2VUE A;  2BXH A;  5IIH A;  1E7C A;  1HK1 A;  3TDL A;  1BKE A;  4IW1 A;  4F5V A;  1HK2 A;  1HK5 A;  1GNI A;  3LU6 A;  2BXO A;  4S1Y A;  1E7A A;  2BXC A;  2VDB A;  5GHK A;  1KXP D;  5HOZ A;  1HK3 A;  5DQF A;  5FUO A;  1E78 A;  1HA2 A;  4L8U A;  4OT2 A;  5IIU A;  1E7B A;  1E7E A;  3B9L A;  5ID7 A;  4F5U A;  1HK4 A;  4L9Q A; 
#chains in the Genus database with same CATH topology
 2BX8 A;  4JK4 A;  1H9Z A;  1GNJ A;  4G01 A;  1VFI A;  5IJF A;  2BXE A;  4TQ0 A;  1FOU A;  2BXA A;  1AO6 A;  1MIY A;  2I30 A;  2AGH B;  3A73 A;  3LU8 A;  2XSI A;  3FWB C;  4N3Z A;  2Z8J A;  5IFO A;  5ID9 A;  4DM0 A;  1BM0 A;  2NNW A;  2EFE A;  5IJE A;  3LU7 A;  2BXL A;  3NVM A;  1MA9 A;  1J78 A;  2XVQ A;  2QM6 A;  2XVU A;  1J7E A;  2V36 A;  2Z8I A;  3FWC C;  3JQZ A;  4HGK A;  4PO0 A;  4F5T A;  4J2V A;  1UOR A;  2CKX A;  4LB9 A;  3FNM A;  3KJL A;  3V03 A;  4G03 A;  4L9K A;  4M70 B;  1E7H A;  2VUF A;  1SB0 A;  4GDX A;  2OT3 A;  1MIW A;  3B9M A;  3GQU A;  1E7G A;  2XVV A;  1LNS A;  1H5W A;  2XW1 A;  4Z9O A;  2BXG A;  4TQ1 A;  4ZBR A;  2BXQ A;  5IJ5 A;  2BXM A;  2OZB B;  2DYO A;  4NAW B;  1O9X A;  1TXU A;  3V08 A;  3UIV A;  2EFC A;  3WHQ A;  1N5U A;  3A75 A;  2DBW A;  2GUT A;  2XMO A;  2YDF A;  1BJ5 A;  3MHS B;  4GDK B;  3JRY A;  3CX9 A;  3MHH B;  2ROH A;  4N0U D;  3BPJ A;  4K2C A;  3WHR A;  3KIK A;  4LUH A;  2E0X A;  2BXB A;  4MBE C;  4I9O A;  4IW2 A;  4LUF A;  1E7F A;  2BXP A;  2DBU A;  4E99 A;  4K71 A;  5BPK A;  2BXK A;  1MUS A;  2LXS A;  2BXF A;  4BY9 C;  2EFH A;  4LB2 A;  4W4U B;  4F5S A;  1TF0 A;  4N0F D;  4OR0 A;  4G04 A;  3NVI A;  1KW2 A;  4HGM B;  1E7I A;  4ZC6 A;  4Z69 A;  3ECP A;  2LQH A;  5IIX A;  4LA0 A;  4D7X A;  4ZCG A;  5B5T A;  3SQJ A;  2AJE A;  4ZBK A;  5GIN A;  1MUH A;  2BXD A;  4GG2 A;  1JNB A;  2LXT A;  5DBY A;  3H3A A;  2BXI A;  3SIU B;  2DBX A;  2KWF A;  2XW0 A;  4FK5 B;  4ZBQ A;  4BKE A;  2E0Y A;  2I2Z A;  2BXN A;  2QMC A;  3H37 A;  3VQI A;  2EFD A;  4EMX A;  4FJC B;  2QHB A;  3M99 C;  1LOT A;  2XVW A;  3V09 A;  4GDL B;  4DHX B;  2LQI A;  2VUE A;  2BXH A;  5IIH A;  1E7C A;  1HK1 A;  4WA6 B;  3WHS A;  2DYM A;  3TDL A;  1BKE A;  2KBZ A;  4IW1 A;  4F5V A;  1NT2 B;  1HK2 A;  1HK5 A;  1GNI A;  3LU6 A;  2BXO A;  5D7G A;  4S1Y A;  1E7A A;  3W1S A;  2BXC A;  4ZUX V;  2VDB A;  2Z8K A;  5GHK A;  1KXP D;  3SIV B;  2DG5 A;  4OTT A;  5HOZ A;  1HK3 A;  2JUH A;  5GIO A;  5DQF A;  1MM8 A;  5FUO A;  1IJG A;  1E78 A;  1HA2 A;  3GQX A;  4L8U A;  1KDX A;  3ICX A;  1VZS A;  2LOQ A;  4OT2 A;  3NMU A;  5IIU A;  4OTU A;  3PLA A;  4C31 B;  1E7B A;  1E7E A;  4FIP B;  3G9K D;  3GA9 L;  3B9L A;  5GIP A;  1MIV A;  5ID7 A;  4F5U A;  2K0N A;  3NVK A;  1HK4 A;  4L9Q A;  2NQO A; 
#chains in the Genus database with same CATH homology
 2BX8 A;  4JK4 A;  1H9Z A;  1GNJ A;  4G01 A;  1VFI A;  5IJF A;  2BXE A;  4TQ0 A;  1FOU A;  2BXA A;  1AO6 A;  1MIY A;  2I30 A;  3A73 A;  3LU8 A;  2XSI A;  3FWB C;  4N3Z A;  2Z8J A;  5IFO A;  5ID9 A;  1BM0 A;  2NNW A;  2EFE A;  5IJE A;  3LU7 A;  2BXL A;  3NVM A;  1MA9 A;  1J78 A;  2XVQ A;  2QM6 A;  2XVU A;  1J7E A;  2V36 A;  2Z8I A;  3FWC C;  3JQZ A;  4HGK A;  4PO0 A;  4F5T A;  4J2V A;  1UOR A;  2CKX A;  4LB9 A;  3FNM A;  3KJL A;  3V03 A;  4G03 A;  4L9K A;  4M70 B;  1E7H A;  2VUF A;  4GDX A;  2OT3 A;  1MIW A;  3B9M A;  3GQU A;  1E7G A;  2XVV A;  1LNS A;  1H5W A;  2XW1 A;  4Z9O A;  2BXG A;  4TQ1 A;  4ZBR A;  2BXQ A;  5IJ5 A;  2BXM A;  2OZB B;  2DYO A;  4NAW B;  1O9X A;  1TXU A;  3V08 A;  3UIV A;  2EFC A;  3WHQ A;  1N5U A;  3A75 A;  2DBW A;  2XMO A;  2YDF A;  1BJ5 A;  3MHS B;  4GDK B;  3JRY A;  3CX9 A;  3MHH B;  2ROH A;  4N0U D;  4K2C A;  3WHR A;  3KIK A;  4LUH A;  2E0X A;  2BXB A;  4MBE C;  4IW2 A;  4LUF A;  1E7F A;  2BXP A;  2DBU A;  4E99 A;  4K71 A;  5BPK A;  2BXK A;  2BXF A;  4BY9 C;  2EFH A;  4LB2 A;  4W4U B;  4F5S A;  1TF0 A;  4N0F D;  4OR0 A;  4G04 A;  3NVI A;  1KW2 A;  4HGM B;  1E7I A;  4ZC6 A;  4Z69 A;  5IIX A;  4LA0 A;  4ZCG A;  5B5T A;  3SQJ A;  2AJE A;  4ZBK A;  5GIN A;  2BXD A;  4GG2 A;  1JNB A;  5DBY A;  3H3A A;  2BXI A;  3SIU B;  2DBX A;  2XW0 A;  4FK5 B;  4ZBQ A;  4BKE A;  2E0Y A;  2I2Z A;  2BXN A;  2QMC A;  3H37 A;  3VQI A;  2EFD A;  4EMX A;  4FJC B;  2QHB A;  3M99 C;  1LOT A;  2XVW A;  3V09 A;  4GDL B;  4DHX B;  2VUE A;  2BXH A;  5IIH A;  1E7C A;  1HK1 A;  4WA6 B;  3WHS A;  2DYM A;  3TDL A;  1BKE A;  2KBZ A;  4IW1 A;  4F5V A;  1NT2 B;  1HK2 A;  1HK5 A;  1GNI A;  3LU6 A;  2BXO A;  5D7G A;  4S1Y A;  1E7A A;  3W1S A;  2BXC A;  4ZUX V;  2VDB A;  2Z8K A;  5GHK A;  1KXP D;  3SIV B;  2DG5 A;  4OTT A;  5HOZ A;  1HK3 A;  2JUH A;  5GIO A;  5DQF A;  5FUO A;  1IJG A;  1E78 A;  1HA2 A;  3GQX A;  4L8U A;  3ICX A;  1VZS A;  2LOQ A;  4OT2 A;  3NMU A;  5IIU A;  4OTU A;  3PLA A;  4C31 B;  1E7B A;  1E7E A;  4FIP B;  3G9K D;  3GA9 L;  3B9L A;  5GIP A;  1MIV A;  5ID7 A;  4F5U A;  3NVK A;  1HK4 A;  4L9Q A;  2NQO A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4N0UD

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations