4PO0A

Crystal structure of leporine serum albumin in complex with naproxen
Total Genus 227
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
227
sequence length
583
structure length
583
Chain Sequence
AHKSEIAHRFNDVGEEHFIGLVLITFSQYLQKCPYEEHAKLVKEVTDLAKACVADESAANCDKSLHDIFGDKICALPSLRDTYGDVADCCEKKEPERNECFLHHKDDKPDLPPFARPEADVLCKAFHDDEKAFFGHYLYEVARRHPYFYAPELLYYAQKYKAILTECCEAADKGACLTPKLDALKEKALISAAQERLRCASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHKECCHGDLLECADDRADLAKYMCEHQETISSHLKECCDKPILEKAHCIYGLHNDETPAGLPAVAEEFVEDKDVCKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLGKAYEATLKKCCATDDPHACYAKVLDEFQPLVDEPKNLVKQNCELYEQLGDYNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGSKCCKHPEAERLPCVEDYLSVVLNRLCVLHEKTPVSEKVTKCCSESLVDRRPCFSALGPDETYVPKEFNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGEFTALLDKCCSAEDKEACFAVEGPKLVESSKATLG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural studies of bovine, equine, and leporine serum albumin complexes with naproxen.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Serum albumin
total genus 227
structure length 583
sequence length 583
ec nomenclature
pdb deposition date 2014-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4po0A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4po0A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4po0A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4po0A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4po0A05
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4po0A06
2BXFA 5ID7A 2XVVA 1MA9A 4J2VA 3LU6A 4S1YA 4EMXA 4LA0A 4Z69A 2BXAA 3SQJA 4ZBRA 1E78A 1E7HA 3JRYA 1E7CA 1N5UA 1HK2A 5FUOA 2XW0A 4L9QA 3B9MA 2BXMA 1HA2A 2XW1A 3CX9A 1KXPD 1E7IA 5DQFA 1KW2A 4LB9A 4N0FD 2BXBA 2YDFA 1O9XA 1HK4A 4N0UD 2XSIA 2BXGA 4OR0A 3V03A 4HGMB 1E7GA 1TF0A 4L8UA 4IW2A 2BXOA 5IIUA 5IIHA 1E7EA 1E7AA 4E99A 4F5VA 1BJ5A 2I30A 2BX8A 1E7BA 1HK5A 1GNJA 3LU7A 4PO0A 5GHKA 1AO6A 2BXIA 2VUFA 5DBYA 4L9KA 5ID9A 3UIVA 4LUFA 1HK3A 5IJFA 5IJEA 1HK1A 4F5SA 5IIXA 4F5TA 1H9ZA 2I2ZA 4IW1A 5IFOA 1UORA 5HOZA 1GNIA 2XVQA 1E7FA 2BXPA 2BXLA 2XVUA 3A73A 4F5UA 2BXDA 3V09A 2BXQA 1BKEA 3TDLA 3V08A 5IJ5A 4G03A 4BKEA 2BXEA 2VUEA 3LU8A 4JK4A 3JQZA 1BM0A 1J7EA 4K2CA 4G04A 4ZBQA 2BXKA 2BXCA 2BXNA 4K71A 4HGKA 4LUHA 3B9LA 4OT2A 4LB2A 2XVWA 1LOTA 2VDBA 1J78A 2BXHA
chains in the Genus database with same CATH superfamily
2BXFA 5ID7A 2XVVA 1MA9A 4ZBKA 1IJGA 2DBUA 3LU6A 4J2VA 1MM8A 4S1YA 4EMXA 2KWFA 3A75A 4LA0A 4Z69A 4GDXA 2XMOA 2BXAA 3SQJA 2NQOA 4ZBRA 1E78A 1E7HA 2AJEA 2NNWA 3JRYA 1MIYA 1E7CA 2EFHA 1N5UA 4NAWB 1HK2A 1SB0A 2E0XA 2XW0A 4FK5B 5FUOA 3SIVB 4BY9C 4L9QA 3B9MA 2BXMA 1HA2A 2GUTA 2XW1A 3CX9A 4W4UB 3NVMA 1KXPD 5B5TA 1E7IA 5DQFA 1KW2A 4LB9A 4N0FD 4TQ0A 3H3AA 3G9KD 2BXBA 2YDFA 3WHRA 1H5WA 1O9XA 1HK4A 2DG5A 2DBWA 4C31B 1MIVA 4N0UD 2XSIA 5GINA 4ZC6A 2K0NA 4OTUA 3WHSA 1MUHA 2BXGA 4OR0A 3GQUA 3FNMA 4HGMB 3V03A 4M70B 1E7GA 2EFDA 3NVIA 1TF0A 1VZSA 4L8UA 4IW2A 3WHQA 1NT2B 2Z8KA 2BXOA 4FJCB 5IIUA 2QMCA 5IIHA 1E7EA 1E7AA 4D7XA 4E99A 4F5VA 1BJ5A 2I30A 2EFEA 2BX8A 3M99C 1E7BA 4FIPB 2E0YA 3SIUB 1HK5A 1GNJA 3LU7A 4PO0A 5GHKA 1VFIA 4Z9OA 2KBZA 4DHXB 4GDLB 1AO6A 2BXIA 3NMUA 4ZCGA 2AGHB 5GIOA 3KIKA 2JUHA 4MBEC 2VUFA 1TXUA 5DBYA 4L9KA 5ID9A 2CKXA 3H37A 2OT3A 1MIWA 4ZUXV 2ROHA 4GG2A 5GIPA 3GA9L 2LQHA 4TQ1A 5D7GA 4LUFA 3UIVA 1HK3A 5IJFA 5IJEA 1HK1A 4F5SA 3NVKA 5IIXA 2LQIA 4WA6B 4F5TA 1H9ZA 2EFCA 2I2ZA 4IW1A 2DYOA 5IFOA 3FWCC 1UORA 3MHSB 5HOZA 5BPKA 2LOQA 1JNBA 4DM0A 1GNIA 3PLAA 3MHHB 2XVQA 1E7FA 4OTTA 2BXPA 2BXLA 2XVUA 4I9OA 2OZBB 3A73A 4F5UA 2BXDA 3W1SA 3V09A 3ICXA 2BXQA 2QM6A 1BKEA 3TDLA 1MUSA 3V08A 2LXTA 5IJ5A 4G03A 4BKEA 1LNSA 2LXSA 2BXEA 2VUEA 3LU8A 4JK4A 3FWBC 3JQZA 1BM0A 1J7EA 4GDKB 4G04A 4K2CA 4ZBQA 2BXKA 2BXCA 2DYMA 4N3ZA 2BXNA 4K71A 4HGKA 4LUHA 2Z8IA 3B9LA 3KJLA 2QHBA 4OT2A 4LB2A 3GQXA 3VQIA 2XVWA 1LOTA 2VDBA 1J78A 3ECPA 1FOUA 2DBXA 2BXHA 2Z8JA 1KDXA 4G01A 3BPJA 2V36A
chains in the Genus database with same CATH topology
2BXFA 5ID7A 2XVVA 1MA9A 4ZBKA 1IJGA 2DBUA 3LU6A 4J2VA 4S1YA 4EMXA 3A75A 4LA0A 4Z69A 4GDXA 2XMOA 2BXAA 3SQJA 2NQOA 4ZBRA 1E78A 1E7HA 2AJEA 2NNWA 3JRYA 1MIYA 1E7CA 2EFHA 1N5UA 4NAWB 1HK2A 2E0XA 4FK5B 2XW0A 5FUOA 3SIVB 4BY9C 4L9QA 3B9MA 2BXMA 1HA2A 2XW1A 3CX9A 4W4UB 3NVMA 1KXPD 5B5TA 1E7IA 5DQFA 1KW2A 4LB9A 4N0FD 4TQ0A 3H3AA 3G9KD 2BXBA 2YDFA 3WHRA 1H5WA 1O9XA 1HK4A 2DG5A 2DBWA 4C31B 1MIVA 4N0UD 2XSIA 5GINA 4ZC6A 4OTUA 3WHSA 2BXGA 4OR0A 3GQUA 3FNMA 4HGMB 3V03A 4M70B 1E7GA 2EFDA 3NVIA 1TF0A 1VZSA 4L8UA 4IW2A 3WHQA 1NT2B 2Z8KA 2BXOA 4FJCB 5IIUA 2QMCA 5IIHA 1E7EA 1E7AA 4E99A 4F5VA 1BJ5A 2I30A 2EFEA 2BX8A 3M99C 1E7BA 4FIPB 2E0YA 3SIUB 1HK5A 1GNJA 3LU7A 4PO0A 5GHKA 1VFIA 4Z9OA 2KBZA 4DHXB 4GDLB 1AO6A 2BXIA 3NMUA 4ZCGA 5GIOA 3KIKA 2JUHA 4MBEC 2VUFA 1TXUA 5DBYA 4L9KA 5ID9A 2CKXA 3H37A 2OT3A 1MIWA 4ZUXV 2ROHA 4GG2A 5GIPA 3GA9L 4TQ1A 5D7GA 3UIVA 4LUFA 1HK3A 5IJFA 5IJEA 1HK1A 4F5SA 3NVKA 5IIXA 4WA6B 4F5TA 1H9ZA 2EFCA 2I2ZA 4IW1A 2DYOA 5IFOA 1UORA 3MHSB 5HOZA 5BPKA 2LOQA 1JNBA 1GNIA 3PLAA 3MHHB 2XVQA 1E7FA 4OTTA 2BXPA 2BXLA 2XVUA 2OZBB 3A73A 4F5UA 2BXDA 3W1SA 3V09A 3ICXA 2BXQA 2QM6A 1BKEA 3TDLA 3V08A 5IJ5A 4G03A 4BKEA 1LNSA 2BXEA 2VUEA 3LU8A 4JK4A 3FWBC 3JQZA 1BM0A 1J7EA 4GDKB 4G04A 4K2CA 4ZBQA 2BXKA 2BXCA 2DYMA 4N3ZA 2BXNA 4K71A 4HGKA 4LUHA 2Z8IA 3B9LA 3KJLA 2QHBA 4OT2A 4LB2A 3GQXA 3VQIA 2XVWA 1LOTA 2VDBA 1J78A 1FOUA 2DBXA 2BXHA 2Z8JA 4G01A 3FWCC 2V36A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXF A;  5ID7 A;  2XVV A;  1MA9 A;  4J2V A;  3LU6 A;  4S1Y A;  4EMX A;  4LA0 A;  4Z69 A;  2BXA A;  3SQJ A;  4ZBR A;  1E78 A;  1E7H A;  3JRY A;  1E7C A;  1N5U A;  1HK2 A;  5FUO A;  2XW0 A;  4L9Q A;  3B9M A;  2BXM A;  1HA2 A;  2XW1 A;  3CX9 A;  1KXP D;  1E7I A;  5DQF A;  1KW2 A;  4LB9 A;  4N0F D;  2BXB A;  2YDF A;  1O9X A;  1HK4 A;  4N0U D;  2XSI A;  2BXG A;  4OR0 A;  3V03 A;  4HGM B;  1E7G A;  1TF0 A;  4L8U A;  4IW2 A;  2BXO A;  5IIU A;  5IIH A;  1E7E A;  1E7A A;  4E99 A;  4F5V A;  1BJ5 A;  2I30 A;  2BX8 A;  1E7B A;  1HK5 A;  1GNJ A;  3LU7 A;  4PO0 A;  5GHK A;  1AO6 A;  2BXI A;  2VUF A;  5DBY A;  4L9K A;  5ID9 A;  3UIV A;  4LUF A;  1HK3 A;  5IJF A;  5IJE A;  1HK1 A;  4F5S A;  5IIX A;  4F5T A;  1H9Z A;  2I2Z A;  4IW1 A;  5IFO A;  1UOR A;  5HOZ A;  1GNI A;  2XVQ A;  1E7F A;  2BXP A;  2BXL A;  2XVU A;  3A73 A;  4F5U A;  2BXD A;  3V09 A;  2BXQ A;  1BKE A;  3TDL A;  3V08 A;  5IJ5 A;  4G03 A;  4BKE A;  2BXE A;  2VUE A;  3LU8 A;  4JK4 A;  3JQZ A;  1BM0 A;  1J7E A;  4K2C A;  4G04 A;  4ZBQ A;  2BXK A;  2BXC A;  2BXN A;  4K71 A;  4HGK A;  4LUH A;  3B9L A;  4OT2 A;  4LB2 A;  2XVW A;  1LOT A;  2VDB A;  1J78 A;  2BXH A; 
#chains in the Genus database with same CATH topology
 2BXF A;  5ID7 A;  2XVV A;  1MA9 A;  4ZBK A;  1IJG A;  2DBU A;  3LU6 A;  4J2V A;  1MM8 A;  4S1Y A;  4EMX A;  2KWF A;  3A75 A;  4LA0 A;  4Z69 A;  4GDX A;  2XMO A;  2BXA A;  3SQJ A;  2NQO A;  4ZBR A;  1E78 A;  1E7H A;  2AJE A;  2NNW A;  3JRY A;  1MIY A;  1E7C A;  2EFH A;  1N5U A;  4NAW B;  1HK2 A;  1SB0 A;  2E0X A;  2XW0 A;  4FK5 B;  5FUO A;  3SIV B;  4BY9 C;  4L9Q A;  3B9M A;  2BXM A;  1HA2 A;  2GUT A;  2XW1 A;  3CX9 A;  4W4U B;  3NVM A;  1KXP D;  5B5T A;  1E7I A;  5DQF A;  1KW2 A;  4LB9 A;  4N0F D;  4TQ0 A;  3H3A A;  3G9K D;  2BXB A;  2YDF A;  3WHR A;  1H5W A;  1O9X A;  1HK4 A;  2DG5 A;  2DBW A;  4C31 B;  1MIV A;  4N0U D;  2XSI A;  5GIN A;  4ZC6 A;  2K0N A;  4OTU A;  3WHS A;  1MUH A;  2BXG A;  4OR0 A;  3GQU A;  3FNM A;  4HGM B;  3V03 A;  4M70 B;  1E7G A;  2EFD A;  3NVI A;  1TF0 A;  1VZS A;  4L8U A;  4IW2 A;  3WHQ A;  1NT2 B;  2Z8K A;  2BXO A;  4FJC B;  5IIU A;  2QMC A;  5IIH A;  1E7E A;  1E7A A;  4D7X A;  4E99 A;  4F5V A;  1BJ5 A;  2I30 A;  2EFE A;  2BX8 A;  3M99 C;  1E7B A;  4FIP B;  2E0Y A;  3SIU B;  1HK5 A;  1GNJ A;  3LU7 A;  4PO0 A;  5GHK A;  1VFI A;  4Z9O A;  2KBZ A;  4DHX B;  4GDL B;  1AO6 A;  2BXI A;  3NMU A;  4ZCG A;  2AGH B;  5GIO A;  3KIK A;  2JUH A;  4MBE C;  2VUF A;  1TXU A;  5DBY A;  4L9K A;  5ID9 A;  2CKX A;  3H37 A;  2OT3 A;  1MIW A;  4ZUX V;  2ROH A;  4GG2 A;  5GIP A;  3GA9 L;  2LQH A;  4TQ1 A;  5D7G A;  4LUF A;  3UIV A;  1HK3 A;  5IJF A;  5IJE A;  1HK1 A;  4F5S A;  3NVK A;  5IIX A;  2LQI A;  4WA6 B;  4F5T A;  1H9Z A;  2EFC A;  2I2Z A;  4IW1 A;  2DYO A;  5IFO A;  3FWC C;  1UOR A;  3MHS B;  5HOZ A;  5BPK A;  2LOQ A;  1JNB A;  4DM0 A;  1GNI A;  3PLA A;  3MHH B;  2XVQ A;  1E7F A;  4OTT A;  2BXP A;  2BXL A;  2XVU A;  4I9O A;  2OZB B;  3A73 A;  4F5U A;  2BXD A;  3W1S A;  3V09 A;  3ICX A;  2BXQ A;  2QM6 A;  1BKE A;  3TDL A;  1MUS A;  3V08 A;  2LXT A;  5IJ5 A;  4G03 A;  4BKE A;  1LNS A;  2LXS A;  2BXE A;  2VUE A;  3LU8 A;  4JK4 A;  3FWB C;  3JQZ A;  1BM0 A;  1J7E A;  4GDK B;  4G04 A;  4K2C A;  4ZBQ A;  2BXK A;  2BXC A;  2DYM A;  4N3Z A;  2BXN A;  4K71 A;  4HGK A;  4LUH A;  2Z8I A;  3B9L A;  3KJL A;  2QHB A;  4OT2 A;  4LB2 A;  3GQX A;  3VQI A;  2XVW A;  1LOT A;  2VDB A;  1J78 A;  3ECP A;  1FOU A;  2DBX A;  2BXH A;  2Z8J A;  1KDX A;  4G01 A;  3BPJ A;  2V36 A; 
#chains in the Genus database with same CATH homology
 2BXF A;  5ID7 A;  2XVV A;  1MA9 A;  4ZBK A;  1IJG A;  2DBU A;  3LU6 A;  4J2V A;  4S1Y A;  4EMX A;  3A75 A;  4LA0 A;  4Z69 A;  4GDX A;  2XMO A;  2BXA A;  3SQJ A;  2NQO A;  4ZBR A;  1E78 A;  1E7H A;  2AJE A;  2NNW A;  3JRY A;  1MIY A;  1E7C A;  2EFH A;  1N5U A;  4NAW B;  1HK2 A;  2E0X A;  4FK5 B;  2XW0 A;  5FUO A;  3SIV B;  4BY9 C;  4L9Q A;  3B9M A;  2BXM A;  1HA2 A;  2XW1 A;  3CX9 A;  4W4U B;  3NVM A;  1KXP D;  5B5T A;  1E7I A;  5DQF A;  1KW2 A;  4LB9 A;  4N0F D;  4TQ0 A;  3H3A A;  3G9K D;  2BXB A;  2YDF A;  3WHR A;  1H5W A;  1O9X A;  1HK4 A;  2DG5 A;  2DBW A;  4C31 B;  1MIV A;  4N0U D;  2XSI A;  5GIN A;  4ZC6 A;  4OTU A;  3WHS A;  2BXG A;  4OR0 A;  3GQU A;  3FNM A;  4HGM B;  3V03 A;  4M70 B;  1E7G A;  2EFD A;  3NVI A;  1TF0 A;  1VZS A;  4L8U A;  4IW2 A;  3WHQ A;  1NT2 B;  2Z8K A;  2BXO A;  4FJC B;  5IIU A;  2QMC A;  5IIH A;  1E7E A;  1E7A A;  4E99 A;  4F5V A;  1BJ5 A;  2I30 A;  2EFE A;  2BX8 A;  3M99 C;  1E7B A;  4FIP B;  2E0Y A;  3SIU B;  1HK5 A;  1GNJ A;  3LU7 A;  4PO0 A;  5GHK A;  1VFI A;  4Z9O A;  2KBZ A;  4DHX B;  4GDL B;  1AO6 A;  2BXI A;  3NMU A;  4ZCG A;  5GIO A;  3KIK A;  2JUH A;  4MBE C;  2VUF A;  1TXU A;  5DBY A;  4L9K A;  5ID9 A;  2CKX A;  3H37 A;  2OT3 A;  1MIW A;  4ZUX V;  2ROH A;  4GG2 A;  5GIP A;  3GA9 L;  4TQ1 A;  5D7G A;  3UIV A;  4LUF A;  1HK3 A;  5IJF A;  5IJE A;  1HK1 A;  4F5S A;  3NVK A;  5IIX A;  4WA6 B;  4F5T A;  1H9Z A;  2EFC A;  2I2Z A;  4IW1 A;  2DYO A;  5IFO A;  1UOR A;  3MHS B;  5HOZ A;  5BPK A;  2LOQ A;  1JNB A;  1GNI A;  3PLA A;  3MHH B;  2XVQ A;  1E7F A;  4OTT A;  2BXP A;  2BXL A;  2XVU A;  2OZB B;  3A73 A;  4F5U A;  2BXD A;  3W1S A;  3V09 A;  3ICX A;  2BXQ A;  2QM6 A;  1BKE A;  3TDL A;  3V08 A;  5IJ5 A;  4G03 A;  4BKE A;  1LNS A;  2BXE A;  2VUE A;  3LU8 A;  4JK4 A;  3FWB C;  3JQZ A;  1BM0 A;  1J7E A;  4GDK B;  4G04 A;  4K2C A;  4ZBQ A;  2BXK A;  2BXC A;  2DYM A;  4N3Z A;  2BXN A;  4K71 A;  4HGK A;  4LUH A;  2Z8I A;  3B9L A;  3KJL A;  2QHB A;  4OT2 A;  4LB2 A;  3GQX A;  3VQI A;  2XVW A;  1LOT A;  2VDB A;  1J78 A;  1FOU A;  2DBX A;  2BXH A;  2Z8J A;  4G01 A;  3FWC C;  2V36 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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