4Z69A

Human serum albumin complexed with palmitic acid and diclofenac
Total Genus 227
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
227
sequence length
581
structure length
581
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of non-steroidal anti-inflammatory drug diclofenac binding to human serum albumin.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Serum albumin
total genus 227
structure length 581
sequence length 581
chains with identical sequence I
ec nomenclature
pdb deposition date 2015-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A05
5ID9A 4G04A 3LU7A 2BXKA 1HK2A 2BXIA 2BXPA 1N5UA 4LUFA 1H9ZA 1BM0A 2BXQA 2BXEA 1HA2A 2BXDA 4K2CA 1J78A 2BXFA 2BXHA 4G03A 4HGMB 4LB9A 2I30A 4N0FD 1E7CA 1E7FA 3B9MA 1UORA 2XVWA 4JK4A 1E78A 4EMXA 4PO0A 4L9QA 5DBYA 2YDFA 1E7HA 2I2ZA 4LUHA 4F5UA 5FUOA 1AO6A 2BXNA 3V09A 2VDBA 4S1YA 2XVVA 1O9XA 5IFOA 4F5SA 2XW1A 3JRYA 4IW1A 4BKEA 1E7AA 4L9KA 1KW2A 4N0UD 1BKEA 4ZBRA 3JQZA 4L8UA 2XVUA 3V03A 4HGKA 1GNIA 1HK1A 1KXPD 2BXMA 1E7EA 1BJ5A 4LA0A 4ZBQA 1E7IA 4LB2A 1TF0A 1MA9A 2XW0A 3V08A 3UIVA 2VUFA 1HK5A 4F5TA 2VUEA 5IJFA 1E7BA 3LU8A 5HOZA 5IIUA 1HK3A 2XSIA 3A73A 3LU6A 2BXLA 1J7EA 2BXBA 2BXGA 2BXAA 5DQFA 1LOTA 3TDLA 3B9LA 4J2VA 3CX9A 4OR0A 3SQJA 4Z69A 1HK4A 5GHKA 2BXCA 5ID7A 4OT2A 2BX8A 4E99A 1E7GA 4F5VA 4K71A 5IJEA 5IIXA 5IIHA 1GNJA 4IW2A 2XVQA 5IJ5A 2BXOA
chains in the Genus database with same CATH superfamily
5ID9A 1IJGA 2OT3A 4GDLB 4G04A 3LU7A 2DBXA 3GQXA 2EFDA 2BXKA 1HK2A 1MUSA 2QM6A 1LNSA 2BXIA 2QHBA 2BXPA 1N5UA 1KDXA 1MIYA 4LUFA 1H9ZA 1BM0A 4FK5B 3NVIA 2BXQA 2CKXA 3FWCC 2BXEA 1HA2A 2BXDA 3NVMA 1J78A 4K2CA 4WA6B 2EFEA 3PLAA 2Z8KA 1SB0A 2BXFA 2BXHA 4G03A 4HGMB 4LB9A 3W1SA 2I30A 2KBZA 4TQ1A 2LOQA 4OTUA 2KWFA 4N0FD 1E7CA 1E7FA 3B9MA 5D7GA 5GIPA 4D7XA 1UORA 3MHSB 4MBEC 2XVWA 4DHXB 4DM0A 4W4UB 3SIUB 4JK4A 3M99C 1E78A 2NNWA 3FNMA 3H37A 4EMXA 4PO0A 4L9QA 3A75A 3ECPA 3NMUA 2LQHA 5DBYA 2YDFA 1E7HA 2I2ZA 4LUHA 4G01A 4F5UA 5BPKA 5FUOA 2BXNA 1AO6A 2LQIA 3V09A 2VDBA 4S1YA 2XVVA 1O9XA 2QMCA 4C31B 5IFOA 4F5SA 3GA9L 4ZCGA 4TQ0A 2XW1A 3JRYA 4IW1A 4BKEA 1E7AA 4L9KA 1KW2A 4GDXA 4N0UD 5GINA 5GIOA 1BKEA 4ZBRA 2XMOA 3JQZA 4FJCB 4L8UA 2LXTA 1H5WA 2XVUA 3WHQA 2E0YA 3V03A 4HGKA 1GNIA 4NAWB 1HK1A 1KXPD 2NQOA 3H3AA 3VQIA 2JUHA 2BXMA 2GUTA 3BPJA 3KIKA 1E7EA 4GG2A 2AJEA 1BJ5A 3MHHB 4LA0A 4ZBQA 1E7IA 1TXUA 3G9KD 4LB2A 1TF0A 1MA9A 1MIWA 2EFHA 2XW0A 3V08A 2EFCA 2VUFA 1HK5A 3FWBC 3UIVA 2VUEA 4F5TA 4ZC6A 2K0NA 3KJLA 5IJFA 1MM8A 2AGHB 1E7BA 3LU8A 5HOZA 5IIUA 2E0XA 4GDKB 3GQUA 1VFIA 2DG5A 1HK3A 2DYOA 2XSIA 3A73A 3LU6A 2DBUA 2BXLA 1J7EA 2BXBA 2BXGA 2DBWA 3WHRA 4Z9OA 1MUHA 2OZBB 2BXAA 5B5TA 4ZBKA 5DQFA 1LOTA 4BY9C 4M70B 1MIVA 2V36A 3TDLA 4OTTA 1FOUA 1VZSA 3B9LA 4J2VA 4N3ZA 2Z8IA 3CX9A 4OR0A 1JNBA 3SQJA 4Z69A 1NT2B 1HK4A 5GHKA 2BXCA 3SIVB 2ROHA 2LXSA 4OT2A 5ID7A 2BX8A 2DYMA 3ICXA 2Z8JA 4E99A 1E7GA 4F5VA 4K71A 4FIPB 5IJEA 3NVKA 4ZUXV 5IIXA 4I9OA 3WHSA 5IIHA 1GNJA 4IW2A 2XVQA 5IJ5A 2BXOA
chains in the Genus database with same CATH topology
5ID9A 1IJGA 2OT3A 4GDLB 4G04A 3LU7A 2DBXA 3GQXA 2EFDA 2BXKA 1HK2A 2QM6A 1LNSA 2BXIA 2QHBA 2BXPA 1N5UA 1MIYA 4LUFA 1H9ZA 1BM0A 4FK5B 3NVIA 2BXQA 2CKXA 3FWCC 2BXEA 1HA2A 2BXDA 3NVMA 1J78A 4K2CA 4WA6B 2EFEA 3PLAA 2Z8KA 2BXFA 2BXHA 4G03A 4HGMB 4LB9A 3W1SA 2I30A 2KBZA 4TQ1A 2LOQA 4OTUA 4N0FD 1E7CA 1E7FA 3B9MA 5D7GA 5GIPA 1UORA 3MHSB 4MBEC 2XVWA 4DHXB 3SIUB 4W4UB 4JK4A 3M99C 1E78A 2NNWA 3FNMA 3H37A 4EMXA 4PO0A 4L9QA 3A75A 3NMUA 5DBYA 2YDFA 1E7HA 2I2ZA 4LUHA 4G01A 4F5UA 5BPKA 5FUOA 2BXNA 1AO6A 3V09A 2VDBA 4S1YA 2XVVA 1O9XA 2QMCA 4C31B 5IFOA 4F5SA 3GA9L 4ZCGA 4TQ0A 2XW1A 3JRYA 4IW1A 4BKEA 1E7AA 4L9KA 1KW2A 4GDXA 4N0UD 5GINA 5GIOA 1BKEA 4ZBRA 2XMOA 3JQZA 4FJCB 4L8UA 1H5WA 2XVUA 3WHQA 2E0YA 3V03A 4HGKA 1GNIA 4NAWB 1HK1A 1KXPD 2NQOA 3H3AA 3VQIA 2JUHA 2BXMA 3KIKA 1E7EA 4GG2A 2AJEA 1BJ5A 3MHHB 4LA0A 4ZBQA 1E7IA 1TXUA 3G9KD 4LB2A 1TF0A 1MA9A 1MIWA 2EFHA 2XW0A 3V08A 2EFCA 2VUFA 1HK5A 3FWBC 3UIVA 2VUEA 4F5TA 4ZC6A 3KJLA 5IJFA 1E7BA 3LU8A 5HOZA 5IIUA 2E0XA 4GDKB 3GQUA 1VFIA 2DG5A 1HK3A 2DYOA 2XSIA 3A73A 3LU6A 2DBUA 2BXLA 1J7EA 2BXBA 2BXGA 2DBWA 3WHRA 4Z9OA 2OZBB 2BXAA 5B5TA 4ZBKA 5DQFA 1LOTA 4BY9C 4M70B 1MIVA 2V36A 3TDLA 4OTTA 1FOUA 1VZSA 3B9LA 4J2VA 4N3ZA 2Z8IA 3CX9A 4OR0A 1JNBA 3SQJA 4Z69A 1NT2B 1HK4A 5GHKA 2BXCA 3SIVB 2ROHA 5ID7A 4OT2A 2BX8A 2DYMA 3ICXA 2Z8JA 4E99A 1E7GA 4F5VA 4K71A 4FIPB 5IJEA 3NVKA 4ZUXV 5IIXA 3WHSA 5IIHA 1GNJA 4IW2A 2XVQA 5IJ5A 2BXOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ID9 A;  4G04 A;  3LU7 A;  2BXK A;  1HK2 A;  2BXI A;  2BXP A;  1N5U A;  4LUF A;  1H9Z A;  1BM0 A;  2BXQ A;  2BXE A;  1HA2 A;  2BXD A;  4K2C A;  1J78 A;  2BXF A;  2BXH A;  4G03 A;  4HGM B;  4LB9 A;  2I30 A;  4N0F D;  1E7C A;  1E7F A;  3B9M A;  1UOR A;  2XVW A;  4JK4 A;  1E78 A;  4EMX A;  4PO0 A;  4L9Q A;  5DBY A;  2YDF A;  1E7H A;  2I2Z A;  4LUH A;  4F5U A;  5FUO A;  1AO6 A;  2BXN A;  3V09 A;  2VDB A;  4S1Y A;  2XVV A;  1O9X A;  5IFO A;  4F5S A;  2XW1 A;  3JRY A;  4IW1 A;  4BKE A;  1E7A A;  4L9K A;  1KW2 A;  4N0U D;  1BKE A;  4ZBR A;  3JQZ A;  4L8U A;  2XVU A;  3V03 A;  4HGK A;  1GNI A;  1HK1 A;  1KXP D;  2BXM A;  1E7E A;  1BJ5 A;  4LA0 A;  4ZBQ A;  1E7I A;  4LB2 A;  1TF0 A;  1MA9 A;  2XW0 A;  3V08 A;  3UIV A;  2VUF A;  1HK5 A;  4F5T A;  2VUE A;  5IJF A;  1E7B A;  3LU8 A;  5HOZ A;  5IIU A;  1HK3 A;  2XSI A;  3A73 A;  3LU6 A;  2BXL A;  1J7E A;  2BXB A;  2BXG A;  2BXA A;  5DQF A;  1LOT A;  3TDL A;  3B9L A;  4J2V A;  3CX9 A;  4OR0 A;  3SQJ A;  4Z69 A;  1HK4 A;  5GHK A;  2BXC A;  5ID7 A;  4OT2 A;  2BX8 A;  4E99 A;  1E7G A;  4F5V A;  4K71 A;  5IJE A;  5IIX A;  5IIH A;  1GNJ A;  4IW2 A;  2XVQ A;  5IJ5 A;  2BXO A; 
#chains in the Genus database with same CATH topology
 5ID9 A;  1IJG A;  2OT3 A;  4GDL B;  4G04 A;  3LU7 A;  2DBX A;  3GQX A;  2EFD A;  2BXK A;  1HK2 A;  1MUS A;  2QM6 A;  1LNS A;  2BXI A;  2QHB A;  2BXP A;  1N5U A;  1KDX A;  1MIY A;  4LUF A;  1H9Z A;  1BM0 A;  4FK5 B;  3NVI A;  2BXQ A;  2CKX A;  3FWC C;  2BXE A;  1HA2 A;  2BXD A;  3NVM A;  1J78 A;  4K2C A;  4WA6 B;  2EFE A;  3PLA A;  2Z8K A;  1SB0 A;  2BXF A;  2BXH A;  4G03 A;  4HGM B;  4LB9 A;  3W1S A;  2I30 A;  2KBZ A;  4TQ1 A;  2LOQ A;  4OTU A;  2KWF A;  4N0F D;  1E7C A;  1E7F A;  3B9M A;  5D7G A;  5GIP A;  4D7X A;  1UOR A;  3MHS B;  4MBE C;  2XVW A;  4DHX B;  4DM0 A;  4W4U B;  3SIU B;  4JK4 A;  3M99 C;  1E78 A;  2NNW A;  3FNM A;  3H37 A;  4EMX A;  4PO0 A;  4L9Q A;  3A75 A;  3ECP A;  3NMU A;  2LQH A;  5DBY A;  2YDF A;  1E7H A;  2I2Z A;  4LUH A;  4G01 A;  4F5U A;  5BPK A;  5FUO A;  2BXN A;  1AO6 A;  2LQI A;  3V09 A;  2VDB A;  4S1Y A;  2XVV A;  1O9X A;  2QMC A;  4C31 B;  5IFO A;  4F5S A;  3GA9 L;  4ZCG A;  4TQ0 A;  2XW1 A;  3JRY A;  4IW1 A;  4BKE A;  1E7A A;  4L9K A;  1KW2 A;  4GDX A;  4N0U D;  5GIN A;  5GIO A;  1BKE A;  4ZBR A;  2XMO A;  3JQZ A;  4FJC B;  4L8U A;  2LXT A;  1H5W A;  2XVU A;  3WHQ A;  2E0Y A;  3V03 A;  4HGK A;  1GNI A;  4NAW B;  1HK1 A;  1KXP D;  2NQO A;  3H3A A;  3VQI A;  2JUH A;  2BXM A;  2GUT A;  3BPJ A;  3KIK A;  1E7E A;  4GG2 A;  2AJE A;  1BJ5 A;  3MHH B;  4LA0 A;  4ZBQ A;  1E7I A;  1TXU A;  3G9K D;  4LB2 A;  1TF0 A;  1MA9 A;  1MIW A;  2EFH A;  2XW0 A;  3V08 A;  2EFC A;  2VUF A;  1HK5 A;  3FWB C;  3UIV A;  2VUE A;  4F5T A;  4ZC6 A;  2K0N A;  3KJL A;  5IJF A;  1MM8 A;  2AGH B;  1E7B A;  3LU8 A;  5HOZ A;  5IIU A;  2E0X A;  4GDK B;  3GQU A;  1VFI A;  2DG5 A;  1HK3 A;  2DYO A;  2XSI A;  3A73 A;  3LU6 A;  2DBU A;  2BXL A;  1J7E A;  2BXB A;  2BXG A;  2DBW A;  3WHR A;  4Z9O A;  1MUH A;  2OZB B;  2BXA A;  5B5T A;  4ZBK A;  5DQF A;  1LOT A;  4BY9 C;  4M70 B;  1MIV A;  2V36 A;  3TDL A;  4OTT A;  1FOU A;  1VZS A;  3B9L A;  4J2V A;  4N3Z A;  2Z8I A;  3CX9 A;  4OR0 A;  1JNB A;  3SQJ A;  4Z69 A;  1NT2 B;  1HK4 A;  5GHK A;  2BXC A;  3SIV B;  2ROH A;  2LXS A;  4OT2 A;  5ID7 A;  2BX8 A;  2DYM A;  3ICX A;  2Z8J A;  4E99 A;  1E7G A;  4F5V A;  4K71 A;  4FIP B;  5IJE A;  3NVK A;  4ZUX V;  5IIX A;  4I9O A;  3WHS A;  5IIH A;  1GNJ A;  4IW2 A;  2XVQ A;  5IJ5 A;  2BXO A; 
#chains in the Genus database with same CATH homology
 5ID9 A;  1IJG A;  2OT3 A;  4GDL B;  4G04 A;  3LU7 A;  2DBX A;  3GQX A;  2EFD A;  2BXK A;  1HK2 A;  2QM6 A;  1LNS A;  2BXI A;  2QHB A;  2BXP A;  1N5U A;  1MIY A;  4LUF A;  1H9Z A;  1BM0 A;  4FK5 B;  3NVI A;  2BXQ A;  2CKX A;  3FWC C;  2BXE A;  1HA2 A;  2BXD A;  3NVM A;  1J78 A;  4K2C A;  4WA6 B;  2EFE A;  3PLA A;  2Z8K A;  2BXF A;  2BXH A;  4G03 A;  4HGM B;  4LB9 A;  3W1S A;  2I30 A;  2KBZ A;  4TQ1 A;  2LOQ A;  4OTU A;  4N0F D;  1E7C A;  1E7F A;  3B9M A;  5D7G A;  5GIP A;  1UOR A;  3MHS B;  4MBE C;  2XVW A;  4DHX B;  3SIU B;  4W4U B;  4JK4 A;  3M99 C;  1E78 A;  2NNW A;  3FNM A;  3H37 A;  4EMX A;  4PO0 A;  4L9Q A;  3A75 A;  3NMU A;  5DBY A;  2YDF A;  1E7H A;  2I2Z A;  4LUH A;  4G01 A;  4F5U A;  5BPK A;  5FUO A;  2BXN A;  1AO6 A;  3V09 A;  2VDB A;  4S1Y A;  2XVV A;  1O9X A;  2QMC A;  4C31 B;  5IFO A;  4F5S A;  3GA9 L;  4ZCG A;  4TQ0 A;  2XW1 A;  3JRY A;  4IW1 A;  4BKE A;  1E7A A;  4L9K A;  1KW2 A;  4GDX A;  4N0U D;  5GIN A;  5GIO A;  1BKE A;  4ZBR A;  2XMO A;  3JQZ A;  4FJC B;  4L8U A;  1H5W A;  2XVU A;  3WHQ A;  2E0Y A;  3V03 A;  4HGK A;  1GNI A;  4NAW B;  1HK1 A;  1KXP D;  2NQO A;  3H3A A;  3VQI A;  2JUH A;  2BXM A;  3KIK A;  1E7E A;  4GG2 A;  2AJE A;  1BJ5 A;  3MHH B;  4LA0 A;  4ZBQ A;  1E7I A;  1TXU A;  3G9K D;  4LB2 A;  1TF0 A;  1MA9 A;  1MIW A;  2EFH A;  2XW0 A;  3V08 A;  2EFC A;  2VUF A;  1HK5 A;  3FWB C;  3UIV A;  2VUE A;  4F5T A;  4ZC6 A;  3KJL A;  5IJF A;  1E7B A;  3LU8 A;  5HOZ A;  5IIU A;  2E0X A;  4GDK B;  3GQU A;  1VFI A;  2DG5 A;  1HK3 A;  2DYO A;  2XSI A;  3A73 A;  3LU6 A;  2DBU A;  2BXL A;  1J7E A;  2BXB A;  2BXG A;  2DBW A;  3WHR A;  4Z9O A;  2OZB B;  2BXA A;  5B5T A;  4ZBK A;  5DQF A;  1LOT A;  4BY9 C;  4M70 B;  1MIV A;  2V36 A;  3TDL A;  4OTT A;  1FOU A;  1VZS A;  3B9L A;  4J2V A;  4N3Z A;  2Z8I A;  3CX9 A;  4OR0 A;  1JNB A;  3SQJ A;  4Z69 A;  1NT2 B;  1HK4 A;  5GHK A;  2BXC A;  3SIV B;  2ROH A;  5ID7 A;  4OT2 A;  2BX8 A;  2DYM A;  3ICX A;  2Z8J A;  4E99 A;  1E7G A;  4F5V A;  4K71 A;  4FIP B;  5IJE A;  3NVK A;  4ZUX V;  5IIX A;  3WHS A;  5IIH A;  1GNJ A;  4IW2 A;  2XVQ A;  5IJ5 A;  2BXO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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