4ZBRA

Crystal structure of equine serum albumin in complex with diclofenac and naproxen
Total Genus 245
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
245
sequence length
580
structure length
580
Chain Sequence
KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKAGCLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYATVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into the Competitive Binding of Diclofenac and Naproxen by Equine Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Serum albumin
total genus 245
structure length 580
sequence length 580
ec nomenclature
pdb deposition date 2015-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbrA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbrA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbrA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbrA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbrA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbrA05
2BXEA 5IJ5A 2BXGA 3SQJA 2VUFA 2BXMA 4HGKA 4L8UA 1AO6A 3LU7A 4EMXA 2BXNA 1GNIA 1KXPD 1HK4A 5HOZA 1GNJA 2BXFA 3LU8A 4K71A 1KW2A 5ID9A 1LOTA 3JRYA 2BX8A 5IIXA 1E7BA 5DBYA 4OT2A 4G04A 4ZBQA 1BM0A 5IJEA 3TDLA 5IIUA 2BXDA 4LB9A 4LA0A 2I2ZA 3A73A 2XSIA 3V09A 1E7FA 3LU6A 4BKEA 1J78A 4E99A 1E7CA 4N0FD 2VUEA 1E7GA 4F5TA 1TF0A 2BXOA 2YDFA 5IJFA 5FUOA 4F5UA 4OR0A 1E7HA 5GHKA 2BXAA 4LUFA 3B9MA 5DQFA 2VDBA 3B9LA 5IIHA 4IW1A 2XW0A 2BXCA 1N5UA 4JK4A 4L9QA 5ID7A 1HK5A 3V08A 1HK1A 4HGMB 1E7AA 2BXIA 4F5VA 1BJ5A 2BXHA 4LUHA 1J7EA 2BXKA 2XVQA 1HK2A 1E7EA 1E7IA 4LB2A 1HA2A 4K2CA 2BXBA 2BXLA 3UIVA 1UORA 2XVUA 2XVVA 2XW1A 1MA9A 3V03A 4IW2A 1BKEA 4J2VA 4N0UD 2BXQA 4F5SA 4Z69A 1HK3A 4ZBRA 1O9XA 3JQZA 4L9KA 1H9ZA 2I30A 4S1YA 4G03A 2XVWA 4PO0A 3CX9A 2BXPA 5IFOA 1E78A
chains in the Genus database with same CATH superfamily
2BXEA 2EFHA 4Z9OA 4TQ0A 3GQUA 5IJ5A 2BXGA 2DBXA 2VUFA 3SQJA 3PLAA 3BPJA 3ECPA 2BXMA 4HGKA 1VZSA 4L8UA 1AO6A 3LU7A 4GDLB 4EMXA 2BXNA 1GNIA 1KXPD 1HK4A 2KBZA 3NVMA 1MIWA 5HOZA 5D7GA 1GNJA 4OTUA 2JUHA 2BXFA 3LU8A 2EFEA 4K71A 1KW2A 4ZBKA 4N3ZA 5ID9A 1LOTA 3GA9L 3JRYA 2BX8A 5B5TA 1MIYA 1H5WA 5BPKA 5IIXA 1E7BA 5DBYA 4OT2A 4G04A 4ZBQA 1BM0A 3NVIA 5IJEA 3TDLA 2OZBB 3KJLA 1MUHA 3MHHB 4D7XA 5IIUA 2KWFA 4G01A 2BXDA 4LB9A 4LA0A 2I2ZA 2NNWA 2OT3A 2XSIA 3A73A 2DYMA 2DG5A 3H3AA 3V09A 4C31B 1MM8A 2Z8IA 1E7FA 4GG2A 4WA6B 4GDXA 3LU6A 1NT2B 3NMUA 3H37A 4FIPB 4BKEA 1J78A 4E99A 1E7CA 2QMCA 4N0FD 5GINA 2V36A 2VUEA 1E7GA 1FOUA 2LQHA 4F5TA 1TF0A 2BXOA 2YDFA 2DBUA 2DYOA 2QM6A 5FUOA 2K0NA 4F5UA 5IJFA 4ZCGA 4OR0A 1E7HA 2GUTA 1IJGA 5GHKA 3KIKA 2Z8JA 5GIOA 2BXAA 4LUFA 3FWCC 3B9MA 3WHQA 4FJCB 5DQFA 3ICXA 2VDBA 3B9LA 5IIHA 4IW1A 2XW0A 2BXCA 1N5UA 4JK4A 2LXTA 4BY9C 4L9QA 5ID7A 3MHSB 2E0XA 1TXUA 3FNMA 3GQXA 1HK5A 2XMOA 3V08A 3SIVB 1HK1A 4HGMB 1E7AA 2BXIA 4F5VA 1BJ5A 2AJEA 1LNSA 2BXHA 4OTTA 1JNBA 3G9KD 4LUHA 3VQIA 4GDKB 3NVKA 1J7EA 2QHBA 1MIVA 2BXKA 2DBWA 2XVQA 3A75A 2ROHA 3FWBC 1HK2A 1E7EA 1E7IA 4LB2A 1HA2A 4I9OA 3M99C 2Z8KA 4K2CA 2BXBA 2NQOA 2BXLA 3SIUB 4NAWB 1SB0A 3WHSA 2CKXA 1UORA 3UIVA 4DM0A 2XVUA 2XVVA 2XW1A 4FK5B 1MUSA 2EFCA 1MA9A 3V03A 2EFDA 4IW2A 1BKEA 2LQIA 4J2VA 4N0UD 1VFIA 2BXQA 1KDXA 4F5SA 4Z69A 4DHXB 1HK3A 2LXSA 4ZBRA 1O9XA 3JQZA 4L9KA 1H9ZA 5GIPA 2I30A 2AGHB 3WHRA 4S1YA 4G03A 2XVWA 4MBEC 4W4UB 4PO0A 3W1SA 3CX9A 2E0YA 4TQ1A 4M70B 4ZUXV 2BXPA 2LOQA 4ZC6A 5IFOA 1E78A
chains in the Genus database with same CATH topology
2BXEA 2EFHA 4Z9OA 4TQ0A 3GQUA 5IJ5A 2BXGA 2DBXA 2VUFA 3SQJA 3PLAA 2BXMA 4HGKA 1VZSA 4L8UA 1AO6A 3LU7A 4GDLB 4EMXA 2BXNA 1GNIA 1KXPD 1HK4A 2KBZA 3NVMA 1MIWA 5HOZA 5D7GA 1GNJA 4OTUA 2JUHA 2BXFA 3LU8A 2EFEA 4K71A 1KW2A 4ZBKA 4N3ZA 5ID9A 1LOTA 3GA9L 3JRYA 2BX8A 5B5TA 1MIYA 1H5WA 5BPKA 5IIXA 1E7BA 5DBYA 4OT2A 4G04A 4ZBQA 1BM0A 3NVIA 5IJEA 3TDLA 2OZBB 3KJLA 3MHHB 5IIUA 4G01A 2BXDA 4LB9A 4LA0A 2I2ZA 2NNWA 2OT3A 2XSIA 3A73A 2DYMA 2DG5A 3H3AA 3V09A 4C31B 2Z8IA 1E7FA 4GG2A 4WA6B 4GDXA 3LU6A 1NT2B 3NMUA 3H37A 4FIPB 4BKEA 1J78A 4E99A 1E7CA 2QMCA 4N0FD 5GINA 2V36A 2VUEA 1E7GA 1FOUA 4F5TA 1TF0A 2BXOA 2YDFA 2DBUA 2DYOA 2QM6A 5FUOA 4F5UA 5IJFA 4ZCGA 4OR0A 1E7HA 5GHKA 1IJGA 5GIOA 3KIKA 2Z8JA 2BXAA 4LUFA 3FWCC 3B9MA 3WHQA 4FJCB 5DQFA 3ICXA 2VDBA 3B9LA 5IIHA 4IW1A 2XW0A 2BXCA 1N5UA 4JK4A 4BY9C 4L9QA 5ID7A 3MHSB 2E0XA 1TXUA 3FNMA 3GQXA 1HK5A 2XMOA 3V08A 3SIVB 1HK1A 4HGMB 1E7AA 2BXIA 4F5VA 1BJ5A 2AJEA 1LNSA 2BXHA 4OTTA 1JNBA 3G9KD 4LUHA 3VQIA 4GDKB 3NVKA 1J7EA 2QHBA 1MIVA 2BXKA 2DBWA 2XVQA 3A75A 2ROHA 3FWBC 1HK2A 1E7EA 1E7IA 4LB2A 1HA2A 3M99C 2Z8KA 4K2CA 2BXBA 2NQOA 2BXLA 3SIUB 4NAWB 3WHSA 2CKXA 1UORA 3UIVA 2XVUA 2XVVA 2XW1A 4FK5B 2EFCA 1MA9A 3V03A 2EFDA 4IW2A 1BKEA 4J2VA 4N0UD 1VFIA 2BXQA 4F5SA 4Z69A 4DHXB 1HK3A 4ZBRA 1O9XA 3JQZA 4L9KA 1H9ZA 5GIPA 2I30A 3WHRA 4S1YA 4G03A 2XVWA 4MBEC 4W4UB 4PO0A 3W1SA 3CX9A 2E0YA 4TQ1A 4M70B 4ZUXV 2BXPA 2LOQA 4ZC6A 5IFOA 1E78A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXE A;  5IJ5 A;  2BXG A;  3SQJ A;  2VUF A;  2BXM A;  4HGK A;  4L8U A;  1AO6 A;  3LU7 A;  4EMX A;  2BXN A;  1GNI A;  1KXP D;  1HK4 A;  5HOZ A;  1GNJ A;  2BXF A;  3LU8 A;  4K71 A;  1KW2 A;  5ID9 A;  1LOT A;  3JRY A;  2BX8 A;  5IIX A;  1E7B A;  5DBY A;  4OT2 A;  4G04 A;  4ZBQ A;  1BM0 A;  5IJE A;  3TDL A;  5IIU A;  2BXD A;  4LB9 A;  4LA0 A;  2I2Z A;  3A73 A;  2XSI A;  3V09 A;  1E7F A;  3LU6 A;  4BKE A;  1J78 A;  4E99 A;  1E7C A;  4N0F D;  2VUE A;  1E7G A;  4F5T A;  1TF0 A;  2BXO A;  2YDF A;  5IJF A;  5FUO A;  4F5U A;  4OR0 A;  1E7H A;  5GHK A;  2BXA A;  4LUF A;  3B9M A;  5DQF A;  2VDB A;  3B9L A;  5IIH A;  4IW1 A;  2XW0 A;  2BXC A;  1N5U A;  4JK4 A;  4L9Q A;  5ID7 A;  1HK5 A;  3V08 A;  1HK1 A;  4HGM B;  1E7A A;  2BXI A;  4F5V A;  1BJ5 A;  2BXH A;  4LUH A;  1J7E A;  2BXK A;  2XVQ A;  1HK2 A;  1E7E A;  1E7I A;  4LB2 A;  1HA2 A;  4K2C A;  2BXB A;  2BXL A;  3UIV A;  1UOR A;  2XVU A;  2XVV A;  2XW1 A;  1MA9 A;  3V03 A;  4IW2 A;  1BKE A;  4J2V A;  4N0U D;  2BXQ A;  4F5S A;  4Z69 A;  1HK3 A;  4ZBR A;  1O9X A;  3JQZ A;  4L9K A;  1H9Z A;  2I30 A;  4S1Y A;  4G03 A;  2XVW A;  4PO0 A;  3CX9 A;  2BXP A;  5IFO A;  1E78 A; 
#chains in the Genus database with same CATH topology
 2BXE A;  2EFH A;  4Z9O A;  4TQ0 A;  3GQU A;  5IJ5 A;  2BXG A;  2DBX A;  2VUF A;  3SQJ A;  3PLA A;  3BPJ A;  3ECP A;  2BXM A;  4HGK A;  1VZS A;  4L8U A;  1AO6 A;  3LU7 A;  4GDL B;  4EMX A;  2BXN A;  1GNI A;  1KXP D;  1HK4 A;  2KBZ A;  3NVM A;  1MIW A;  5HOZ A;  5D7G A;  1GNJ A;  4OTU A;  2JUH A;  2BXF A;  3LU8 A;  2EFE A;  4K71 A;  1KW2 A;  4ZBK A;  4N3Z A;  5ID9 A;  1LOT A;  3GA9 L;  3JRY A;  2BX8 A;  5B5T A;  1MIY A;  1H5W A;  5BPK A;  5IIX A;  1E7B A;  5DBY A;  4OT2 A;  4G04 A;  4ZBQ A;  1BM0 A;  3NVI A;  5IJE A;  3TDL A;  2OZB B;  3KJL A;  1MUH A;  3MHH B;  4D7X A;  5IIU A;  2KWF A;  4G01 A;  2BXD A;  4LB9 A;  4LA0 A;  2I2Z A;  2NNW A;  2OT3 A;  2XSI A;  3A73 A;  2DYM A;  2DG5 A;  3H3A A;  3V09 A;  4C31 B;  1MM8 A;  2Z8I A;  1E7F A;  4GG2 A;  4WA6 B;  4GDX A;  3LU6 A;  1NT2 B;  3NMU A;  3H37 A;  4FIP B;  4BKE A;  1J78 A;  4E99 A;  1E7C A;  2QMC A;  4N0F D;  5GIN A;  2V36 A;  2VUE A;  1E7G A;  1FOU A;  2LQH A;  4F5T A;  1TF0 A;  2BXO A;  2YDF A;  2DBU A;  2DYO A;  2QM6 A;  5FUO A;  2K0N A;  4F5U A;  5IJF A;  4ZCG A;  4OR0 A;  1E7H A;  2GUT A;  1IJG A;  5GHK A;  3KIK A;  2Z8J A;  5GIO A;  2BXA A;  4LUF A;  3FWC C;  3B9M A;  3WHQ A;  4FJC B;  5DQF A;  3ICX A;  2VDB A;  3B9L A;  5IIH A;  4IW1 A;  2XW0 A;  2BXC A;  1N5U A;  4JK4 A;  2LXT A;  4BY9 C;  4L9Q A;  5ID7 A;  3MHS B;  2E0X A;  1TXU A;  3FNM A;  3GQX A;  1HK5 A;  2XMO A;  3V08 A;  3SIV B;  1HK1 A;  4HGM B;  1E7A A;  2BXI A;  4F5V A;  1BJ5 A;  2AJE A;  1LNS A;  2BXH A;  4OTT A;  1JNB A;  3G9K D;  4LUH A;  3VQI A;  4GDK B;  3NVK A;  1J7E A;  2QHB A;  1MIV A;  2BXK A;  2DBW A;  2XVQ A;  3A75 A;  2ROH A;  3FWB C;  1HK2 A;  1E7E A;  1E7I A;  4LB2 A;  1HA2 A;  4I9O A;  3M99 C;  2Z8K A;  4K2C A;  2BXB A;  2NQO A;  2BXL A;  3SIU B;  4NAW B;  1SB0 A;  3WHS A;  2CKX A;  1UOR A;  3UIV A;  4DM0 A;  2XVU A;  2XVV A;  2XW1 A;  4FK5 B;  1MUS A;  2EFC A;  1MA9 A;  3V03 A;  2EFD A;  4IW2 A;  1BKE A;  2LQI A;  4J2V A;  4N0U D;  1VFI A;  2BXQ A;  1KDX A;  4F5S A;  4Z69 A;  4DHX B;  1HK3 A;  2LXS A;  4ZBR A;  1O9X A;  3JQZ A;  4L9K A;  1H9Z A;  5GIP A;  2I30 A;  2AGH B;  3WHR A;  4S1Y A;  4G03 A;  2XVW A;  4MBE C;  4W4U B;  4PO0 A;  3W1S A;  3CX9 A;  2E0Y A;  4TQ1 A;  4M70 B;  4ZUX V;  2BXP A;  2LOQ A;  4ZC6 A;  5IFO A;  1E78 A; 
#chains in the Genus database with same CATH homology
 2BXE A;  2EFH A;  4Z9O A;  4TQ0 A;  3GQU A;  5IJ5 A;  2BXG A;  2DBX A;  2VUF A;  3SQJ A;  3PLA A;  2BXM A;  4HGK A;  1VZS A;  4L8U A;  1AO6 A;  3LU7 A;  4GDL B;  4EMX A;  2BXN A;  1GNI A;  1KXP D;  1HK4 A;  2KBZ A;  3NVM A;  1MIW A;  5HOZ A;  5D7G A;  1GNJ A;  4OTU A;  2JUH A;  2BXF A;  3LU8 A;  2EFE A;  4K71 A;  1KW2 A;  4ZBK A;  4N3Z A;  5ID9 A;  1LOT A;  3GA9 L;  3JRY A;  2BX8 A;  5B5T A;  1MIY A;  1H5W A;  5BPK A;  5IIX A;  1E7B A;  5DBY A;  4OT2 A;  4G04 A;  4ZBQ A;  1BM0 A;  3NVI A;  5IJE A;  3TDL A;  2OZB B;  3KJL A;  3MHH B;  5IIU A;  4G01 A;  2BXD A;  4LB9 A;  4LA0 A;  2I2Z A;  2NNW A;  2OT3 A;  2XSI A;  3A73 A;  2DYM A;  2DG5 A;  3H3A A;  3V09 A;  4C31 B;  2Z8I A;  1E7F A;  4GG2 A;  4WA6 B;  4GDX A;  3LU6 A;  1NT2 B;  3NMU A;  3H37 A;  4FIP B;  4BKE A;  1J78 A;  4E99 A;  1E7C A;  2QMC A;  4N0F D;  5GIN A;  2V36 A;  2VUE A;  1E7G A;  1FOU A;  4F5T A;  1TF0 A;  2BXO A;  2YDF A;  2DBU A;  2DYO A;  2QM6 A;  5FUO A;  4F5U A;  5IJF A;  4ZCG A;  4OR0 A;  1E7H A;  5GHK A;  1IJG A;  5GIO A;  3KIK A;  2Z8J A;  2BXA A;  4LUF A;  3FWC C;  3B9M A;  3WHQ A;  4FJC B;  5DQF A;  3ICX A;  2VDB A;  3B9L A;  5IIH A;  4IW1 A;  2XW0 A;  2BXC A;  1N5U A;  4JK4 A;  4BY9 C;  4L9Q A;  5ID7 A;  3MHS B;  2E0X A;  1TXU A;  3FNM A;  3GQX A;  1HK5 A;  2XMO A;  3V08 A;  3SIV B;  1HK1 A;  4HGM B;  1E7A A;  2BXI A;  4F5V A;  1BJ5 A;  2AJE A;  1LNS A;  2BXH A;  4OTT A;  1JNB A;  3G9K D;  4LUH A;  3VQI A;  4GDK B;  3NVK A;  1J7E A;  2QHB A;  1MIV A;  2BXK A;  2DBW A;  2XVQ A;  3A75 A;  2ROH A;  3FWB C;  1HK2 A;  1E7E A;  1E7I A;  4LB2 A;  1HA2 A;  3M99 C;  2Z8K A;  4K2C A;  2BXB A;  2NQO A;  2BXL A;  3SIU B;  4NAW B;  3WHS A;  2CKX A;  1UOR A;  3UIV A;  2XVU A;  2XVV A;  2XW1 A;  4FK5 B;  2EFC A;  1MA9 A;  3V03 A;  2EFD A;  4IW2 A;  1BKE A;  4J2V A;  4N0U D;  1VFI A;  2BXQ A;  4F5S A;  4Z69 A;  4DHX B;  1HK3 A;  4ZBR A;  1O9X A;  3JQZ A;  4L9K A;  1H9Z A;  5GIP A;  2I30 A;  3WHR A;  4S1Y A;  4G03 A;  2XVW A;  4MBE C;  4W4U B;  4PO0 A;  3W1S A;  3CX9 A;  2E0Y A;  4TQ1 A;  4M70 B;  4ZUX V;  2BXP A;  2LOQ A;  4ZC6 A;  5IFO A;  1E78 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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