4BKEA

Recombinant human serum albumin with palmitic acid. synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site ii of human serum albumin
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords SERUM ALBUMIN
publication title Synthetic Cationic Antimicrobial Peptides Bind with Their Hydrophobic Parts to Drug Site II of Human Serum Albumin.
pubmed doi rcsb
source organism Homo sapiens
total genus 224
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2013-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA05
2BXGA 3JRYA 5IIXA 2XVVA 5IIHA 4F5UA 1O9XA 4IW2A 2VUEA 5ID7A 1MA9A 4OR0A 2BX8A 4N0FD 2VDBA 3B9LA 2BXMA 1J78A 1J7EA 1HK5A 5DBYA 5FUOA 1KXPD 4IW1A 4OT2A 1BM0A 2BXNA 1KW2A 4K71A 3V03A 5IJFA 3LU8A 4L8UA 2BXQA 1E7BA 1GNIA 4JK4A 2BXIA 2BXBA 3CX9A 2XVWA 2BXCA 2XSIA 1HK3A 3UIVA 4F5TA 1H9ZA 2BXOA 1BKEA 2BXLA 1E78A 1HA2A 3JQZA 4PO0A 4EMXA 3LU6A 4S1YA 1HK2A 4LA0A 4ZBQA 1E7EA 1BJ5A 4G03A 2BXKA 3A73A 2VUFA 1E7AA 2BXDA 4LB9A 4LUFA 2YDFA 1N5UA 4F5SA 2XVQA 3B9MA 1E7CA 1GNJA 2XVUA 4HGKA 1AO6A 4LUHA 1UORA 5ID9A 1E7FA 5DQFA 1HK4A 1E7GA 2XW0A 4Z69A 1HK1A 3SQJA 4F5VA 4N0UD 4BKEA 4E99A 2XW1A 4L9QA 5IIUA 3LU7A 1TF0A 2I30A 2BXFA 4HGMB 2BXEA 1E7IA 5GHKA 4G04A 1E7HA 1LOTA 5HOZA 3V09A 2I2ZA 2BXAA 4L9KA 2BXHA 4J2VA 4ZBRA 2BXPA 4K2CA 3TDLA 3V08A 5IJEA 5IJ5A 4LB2A 5IFOA
chains in the Genus database with same CATH superfamily
2BXGA 2DYMA 1MIVA 2OZBB 2QHBA 3JRYA 5IIXA 2XVVA 5IIHA 4F5UA 4LB2A 1O9XA 4IW2A 2EFCA 2EFEA 2VUEA 1SB0A 1MA9A 4OR0A 5ID7A 2BX8A 4GDXA 2LOQA 2VDBA 3B9LA 4N0FD 2BXMA 3M99C 1J78A 3SIVB 3ICXA 3GA9L 1J7EA 1HK5A 5DBYA 5B5TA 3G9KD 3NMUA 5FUOA 3SIUB 1KXPD 1FOUA 4IW1A 1MUSA 2LXSA 4OT2A 1BM0A 5BPKA 2BXNA 2K0NA 3H37A 4GG2A 1KW2A 1VFIA 1LNSA 4K71A 4Z9OA 3V03A 5IJFA 3W1SA 2LQIA 4DM0A 3LU8A 4L8UA 2BXQA 1E7BA 4D7XA 1GNIA 4JK4A 2BXIA 2EFDA 2E0YA 2BXBA 3CX9A 2DG5A 2XVWA 3NVMA 4I9OA 4NAWB 2BXCA 2XSIA 1HK3A 5GIPA 3UIVA 4F5TA 1H9ZA 2BXOA 1BKEA 2BXLA 2CKXA 3BPJA 1E78A 1MIWA 1HA2A 3JQZA 2Z8IA 4PO0A 4EMXA 3NVIA 3KJLA 4ZC6A 3PLAA 4DHXB 4OTUA 3LU6A 2QM6A 2XMOA 2DBUA 4S1YA 1HK2A 4LA0A 4FJCB 3NVKA 2JUHA 4ZBQA 2GUTA 4M70B 1TXUA 1E7EA 3MHSB 1BJ5A 3GQXA 3H3AA 4G03A 1VZSA 2Z8KA 1MUHA 2BXKA 2NQOA 2AGHB 2EFHA 3A73A 2VUFA 1E7AA 4TQ0A 2BXDA 2LQHA 4LB9A 4LUFA 2YDFA 5GIOA 2LXTA 1N5UA 1MM8A 2ROHA 4F5SA 2XVQA 3B9MA 4WA6B 1E7CA 3FNMA 3ECPA 4FK5B 2OT3A 1GNJA 3A75A 1NT2B 2AJEA 2XVUA 4GDLB 4HGKA 5GINA 3WHQA 1AO6A 3FWCC 2DBWA 4LUHA 1MIYA 2E0XA 4ZUXV 1UORA 3GQUA 5ID9A 1E7FA 5DQFA 1HK4A 1E7GA 2XW0A 3WHRA 4Z69A 1HK1A 3SQJA 2NNWA 4TQ1A 4F5VA 4N0UD 2Z8JA 1JNBA 4GDKB 4BKEA 2QMCA 2DYOA 4W4UB 2V36A 4E99A 2XW1A 4L9QA 4ZCGA 4BY9C 3VQIA 5IIUA 3LU7A 1TF0A 4FIPB 4OTTA 2I30A 3MHHB 2BXFA 4HGMB 4N3ZA 2BXEA 1H5WA 1E7IA 2KWFA 4ZBKA 5GHKA 5D7GA 2KBZA 4G04A 1E7HA 1LOTA 5HOZA 3V09A 3WHSA 3KIKA 2I2ZA 2BXAA 4L9KA 4MBEC 1IJGA 2BXHA 3FWBC 4J2VA 4ZBRA 4C31B 2BXPA 4K2CA 3TDLA 3V08A 5IJEA 1KDXA 5IJ5A 4G01A 2DBXA 5IFOA
chains in the Genus database with same CATH topology
2BXGA 2DYMA 1MIVA 2OZBB 2QHBA 3JRYA 5IIXA 2XVVA 5IIHA 4F5UA 4LB2A 1O9XA 4IW2A 2EFCA 2EFEA 2VUEA 5ID7A 1MA9A 4OR0A 2BX8A 4GDXA 2LOQA 2VDBA 3B9LA 4N0FD 2BXMA 3M99C 1J78A 3SIVB 3ICXA 3GA9L 1J7EA 1HK5A 5DBYA 5B5TA 3G9KD 3NMUA 5FUOA 3SIUB 1KXPD 1FOUA 4IW1A 4OT2A 1BM0A 5BPKA 2BXNA 3H37A 4GG2A 1KW2A 1VFIA 1LNSA 4K71A 4Z9OA 3V03A 5IJFA 3W1SA 3LU8A 4L8UA 2BXQA 1E7BA 1GNIA 4JK4A 2BXIA 2E0YA 2EFDA 2BXBA 3CX9A 2DG5A 2XVWA 3NVMA 4NAWB 2BXCA 2XSIA 1HK3A 5GIPA 3UIVA 4F5TA 1H9ZA 2BXOA 1BKEA 2BXLA 2CKXA 1E78A 1MIWA 1HA2A 3JQZA 2Z8IA 4PO0A 4EMXA 3NVIA 3KJLA 4ZC6A 3PLAA 4DHXB 4OTUA 3LU6A 2QM6A 2XMOA 2DBUA 4S1YA 1HK2A 4LA0A 4FJCB 3NVKA 2JUHA 4ZBQA 4M70B 1TXUA 1E7EA 3MHSB 1BJ5A 3GQXA 3H3AA 4G03A 1VZSA 2Z8KA 2BXKA 2NQOA 2EFHA 3A73A 2VUFA 1E7AA 4TQ0A 2BXDA 4LB9A 4LUFA 2YDFA 5GIOA 1N5UA 2ROHA 4F5SA 2XVQA 3B9MA 4WA6B 1E7CA 3FNMA 4FK5B 2OT3A 1GNJA 3A75A 1NT2B 2AJEA 2XVUA 4GDLB 4HGKA 5GINA 3WHQA 1AO6A 3FWCC 2DBWA 4LUHA 1MIYA 2E0XA 4ZUXV 1UORA 3GQUA 5ID9A 1E7FA 5DQFA 1HK4A 1E7GA 2XW0A 3WHRA 4Z69A 1HK1A 3SQJA 2NNWA 4TQ1A 4F5VA 4N0UD 2Z8JA 1JNBA 4GDKB 4BKEA 2QMCA 2DYOA 4W4UB 2V36A 4E99A 2XW1A 4L9QA 4ZCGA 4BY9C 3VQIA 5IIUA 3LU7A 1TF0A 4FIPB 4OTTA 2I30A 3MHHB 2BXFA 4HGMB 4N3ZA 2BXEA 1H5WA 1E7IA 4ZBKA 5GHKA 5D7GA 2KBZA 4G04A 1E7HA 1LOTA 5HOZA 3V09A 3WHSA 3KIKA 2I2ZA 2BXAA 4L9KA 4MBEC 1IJGA 2BXHA 3FWBC 4J2VA 4ZBRA 4C31B 2BXPA 4K2CA 3TDLA 3V08A 5IJEA 5IJ5A 4G01A 2DBXA 5IFOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXG A;  3JRY A;  5IIX A;  2XVV A;  5IIH A;  4F5U A;  1O9X A;  4IW2 A;  2VUE A;  5ID7 A;  1MA9 A;  4OR0 A;  2BX8 A;  4N0F D;  2VDB A;  3B9L A;  2BXM A;  1J78 A;  1J7E A;  1HK5 A;  5DBY A;  5FUO A;  1KXP D;  4IW1 A;  4OT2 A;  1BM0 A;  2BXN A;  1KW2 A;  4K71 A;  3V03 A;  5IJF A;  3LU8 A;  4L8U A;  2BXQ A;  1E7B A;  1GNI A;  4JK4 A;  2BXI A;  2BXB A;  3CX9 A;  2XVW A;  2BXC A;  2XSI A;  1HK3 A;  3UIV A;  4F5T A;  1H9Z A;  2BXO A;  1BKE A;  2BXL A;  1E78 A;  1HA2 A;  3JQZ A;  4PO0 A;  4EMX A;  3LU6 A;  4S1Y A;  1HK2 A;  4LA0 A;  4ZBQ A;  1E7E A;  1BJ5 A;  4G03 A;  2BXK A;  3A73 A;  2VUF A;  1E7A A;  2BXD A;  4LB9 A;  4LUF A;  2YDF A;  1N5U A;  4F5S A;  2XVQ A;  3B9M A;  1E7C A;  1GNJ A;  2XVU A;  4HGK A;  1AO6 A;  4LUH A;  1UOR A;  5ID9 A;  1E7F A;  5DQF A;  1HK4 A;  1E7G A;  2XW0 A;  4Z69 A;  1HK1 A;  3SQJ A;  4F5V A;  4N0U D;  4BKE A;  4E99 A;  2XW1 A;  4L9Q A;  5IIU A;  3LU7 A;  1TF0 A;  2I30 A;  2BXF A;  4HGM B;  2BXE A;  1E7I A;  5GHK A;  4G04 A;  1E7H A;  1LOT A;  5HOZ A;  3V09 A;  2I2Z A;  2BXA A;  4L9K A;  2BXH A;  4J2V A;  4ZBR A;  2BXP A;  4K2C A;  3TDL A;  3V08 A;  5IJE A;  5IJ5 A;  4LB2 A;  5IFO A; 
#chains in the Genus database with same CATH topology
 2BXG A;  2DYM A;  1MIV A;  2OZB B;  2QHB A;  3JRY A;  5IIX A;  2XVV A;  5IIH A;  4F5U A;  4LB2 A;  1O9X A;  4IW2 A;  2EFC A;  2EFE A;  2VUE A;  1SB0 A;  1MA9 A;  4OR0 A;  5ID7 A;  2BX8 A;  4GDX A;  2LOQ A;  2VDB A;  3B9L A;  4N0F D;  2BXM A;  3M99 C;  1J78 A;  3SIV B;  3ICX A;  3GA9 L;  1J7E A;  1HK5 A;  5DBY A;  5B5T A;  3G9K D;  3NMU A;  5FUO A;  3SIU B;  1KXP D;  1FOU A;  4IW1 A;  1MUS A;  2LXS A;  4OT2 A;  1BM0 A;  5BPK A;  2BXN A;  2K0N A;  3H37 A;  4GG2 A;  1KW2 A;  1VFI A;  1LNS A;  4K71 A;  4Z9O A;  3V03 A;  5IJF A;  3W1S A;  2LQI A;  4DM0 A;  3LU8 A;  4L8U A;  2BXQ A;  1E7B A;  4D7X A;  1GNI A;  4JK4 A;  2BXI A;  2EFD A;  2E0Y A;  2BXB A;  3CX9 A;  2DG5 A;  2XVW A;  3NVM A;  4I9O A;  4NAW B;  2BXC A;  2XSI A;  1HK3 A;  5GIP A;  3UIV A;  4F5T A;  1H9Z A;  2BXO A;  1BKE A;  2BXL A;  2CKX A;  3BPJ A;  1E78 A;  1MIW A;  1HA2 A;  3JQZ A;  2Z8I A;  4PO0 A;  4EMX A;  3NVI A;  3KJL A;  4ZC6 A;  3PLA A;  4DHX B;  4OTU A;  3LU6 A;  2QM6 A;  2XMO A;  2DBU A;  4S1Y A;  1HK2 A;  4LA0 A;  4FJC B;  3NVK A;  2JUH A;  4ZBQ A;  2GUT A;  4M70 B;  1TXU A;  1E7E A;  3MHS B;  1BJ5 A;  3GQX A;  3H3A A;  4G03 A;  1VZS A;  2Z8K A;  1MUH A;  2BXK A;  2NQO A;  2AGH B;  2EFH A;  3A73 A;  2VUF A;  1E7A A;  4TQ0 A;  2BXD A;  2LQH A;  4LB9 A;  4LUF A;  2YDF A;  5GIO A;  2LXT A;  1N5U A;  1MM8 A;  2ROH A;  4F5S A;  2XVQ A;  3B9M A;  4WA6 B;  1E7C A;  3FNM A;  3ECP A;  4FK5 B;  2OT3 A;  1GNJ A;  3A75 A;  1NT2 B;  2AJE A;  2XVU A;  4GDL B;  4HGK A;  5GIN A;  3WHQ A;  1AO6 A;  3FWC C;  2DBW A;  4LUH A;  1MIY A;  2E0X A;  4ZUX V;  1UOR A;  3GQU A;  5ID9 A;  1E7F A;  5DQF A;  1HK4 A;  1E7G A;  2XW0 A;  3WHR A;  4Z69 A;  1HK1 A;  3SQJ A;  2NNW A;  4TQ1 A;  4F5V A;  4N0U D;  2Z8J A;  1JNB A;  4GDK B;  4BKE A;  2QMC A;  2DYO A;  4W4U B;  2V36 A;  4E99 A;  2XW1 A;  4L9Q A;  4ZCG A;  4BY9 C;  3VQI A;  5IIU A;  3LU7 A;  1TF0 A;  4FIP B;  4OTT A;  2I30 A;  3MHH B;  2BXF A;  4HGM B;  4N3Z A;  2BXE A;  1H5W A;  1E7I A;  2KWF A;  4ZBK A;  5GHK A;  5D7G A;  2KBZ A;  4G04 A;  1E7H A;  1LOT A;  5HOZ A;  3V09 A;  3WHS A;  3KIK A;  2I2Z A;  2BXA A;  4L9K A;  4MBE C;  1IJG A;  2BXH A;  3FWB C;  4J2V A;  4ZBR A;  4C31 B;  2BXP A;  4K2C A;  3TDL A;  3V08 A;  5IJE A;  1KDX A;  5IJ5 A;  4G01 A;  2DBX A;  5IFO A; 
#chains in the Genus database with same CATH homology
 2BXG A;  2DYM A;  1MIV A;  2OZB B;  2QHB A;  3JRY A;  5IIX A;  2XVV A;  5IIH A;  4F5U A;  4LB2 A;  1O9X A;  4IW2 A;  2EFC A;  2EFE A;  2VUE A;  5ID7 A;  1MA9 A;  4OR0 A;  2BX8 A;  4GDX A;  2LOQ A;  2VDB A;  3B9L A;  4N0F D;  2BXM A;  3M99 C;  1J78 A;  3SIV B;  3ICX A;  3GA9 L;  1J7E A;  1HK5 A;  5DBY A;  5B5T A;  3G9K D;  3NMU A;  5FUO A;  3SIU B;  1KXP D;  1FOU A;  4IW1 A;  4OT2 A;  1BM0 A;  5BPK A;  2BXN A;  3H37 A;  4GG2 A;  1KW2 A;  1VFI A;  1LNS A;  4K71 A;  4Z9O A;  3V03 A;  5IJF A;  3W1S A;  3LU8 A;  4L8U A;  2BXQ A;  1E7B A;  1GNI A;  4JK4 A;  2BXI A;  2E0Y A;  2EFD A;  2BXB A;  3CX9 A;  2DG5 A;  2XVW A;  3NVM A;  4NAW B;  2BXC A;  2XSI A;  1HK3 A;  5GIP A;  3UIV A;  4F5T A;  1H9Z A;  2BXO A;  1BKE A;  2BXL A;  2CKX A;  1E78 A;  1MIW A;  1HA2 A;  3JQZ A;  2Z8I A;  4PO0 A;  4EMX A;  3NVI A;  3KJL A;  4ZC6 A;  3PLA A;  4DHX B;  4OTU A;  3LU6 A;  2QM6 A;  2XMO A;  2DBU A;  4S1Y A;  1HK2 A;  4LA0 A;  4FJC B;  3NVK A;  2JUH A;  4ZBQ A;  4M70 B;  1TXU A;  1E7E A;  3MHS B;  1BJ5 A;  3GQX A;  3H3A A;  4G03 A;  1VZS A;  2Z8K A;  2BXK A;  2NQO A;  2EFH A;  3A73 A;  2VUF A;  1E7A A;  4TQ0 A;  2BXD A;  4LB9 A;  4LUF A;  2YDF A;  5GIO A;  1N5U A;  2ROH A;  4F5S A;  2XVQ A;  3B9M A;  4WA6 B;  1E7C A;  3FNM A;  4FK5 B;  2OT3 A;  1GNJ A;  3A75 A;  1NT2 B;  2AJE A;  2XVU A;  4GDL B;  4HGK A;  5GIN A;  3WHQ A;  1AO6 A;  3FWC C;  2DBW A;  4LUH A;  1MIY A;  2E0X A;  4ZUX V;  1UOR A;  3GQU A;  5ID9 A;  1E7F A;  5DQF A;  1HK4 A;  1E7G A;  2XW0 A;  3WHR A;  4Z69 A;  1HK1 A;  3SQJ A;  2NNW A;  4TQ1 A;  4F5V A;  4N0U D;  2Z8J A;  1JNB A;  4GDK B;  4BKE A;  2QMC A;  2DYO A;  4W4U B;  2V36 A;  4E99 A;  2XW1 A;  4L9Q A;  4ZCG A;  4BY9 C;  3VQI A;  5IIU A;  3LU7 A;  1TF0 A;  4FIP B;  4OTT A;  2I30 A;  3MHH B;  2BXF A;  4HGM B;  4N3Z A;  2BXE A;  1H5W A;  1E7I A;  4ZBK A;  5GHK A;  5D7G A;  2KBZ A;  4G04 A;  1E7H A;  1LOT A;  5HOZ A;  3V09 A;  3WHS A;  3KIK A;  2I2Z A;  2BXA A;  4L9K A;  4MBE C;  1IJG A;  2BXH A;  3FWB C;  4J2V A;  4ZBR A;  4C31 B;  2BXP A;  4K2C A;  3TDL A;  3V08 A;  5IJE A;  5IJ5 A;  4G01 A;  2DBX A;  5IFO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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