4D7XA

Solution structure of the mediator gall11 kix domain of c. glabrata
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
86
structure length
86
Chain Sequence
MSSKETIPMHQRSQNVAELLTVLMDINKINGGDSTTAEKMKVHAKSFEAALFEKSSSKEEYQKTMKSKIDAMRSTRDKRKRESVGS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction.
pubmed doi rcsb
molecule tags Transcription
source organism Candida glabrata
molecule keywords MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15
total genus 36
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2014-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16987 KIX_2 KIX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.20 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Coactivator CBP, KIX domain 4d7xA00
1KDXA 2AGHB 2LXTA 2K0NA 4D7XA 1SB0A 2LQHA 2LQIA 2GUTA 2LXSA 4I9OA 2KWFA
chains in the Genus database with same CATH superfamily
3LU6A 2VUEA 2XSIA 1LNSA 2QMCA 4G03A 3UIVA 1J78A 3W1SA 1H5WA 4WA6B 2LQHA 4OTUA 5IJ5A 3KIKA 1MIWA 2XVQA 5HOZA 2XMOA 3SIUB 1HK1A 1J7EA 1E7HA 2KBZA 4MBEC 2BXAA 3V09A 3ECPA 2DBXA 2LXTA 2NQOA 4IW2A 4G01A 2BXBA 4Z69A 1GNJA 2DBWA 2XW0A 3B9LA 4ZUXV 4F5UA 4I9OA 2KWFA 1KW2A 2DYMA 1HK4A 1H9ZA 2YDFA 4G04A 1BM0A 1FOUA 1VZSA 1UORA 3A75A 3LU7A 4LA0A 3G9KD 2XVWA 2BXLA 2BXGA 1E7GA 2JUHA 4N0FD 4N3ZA 5IIUA 3NVIA 2LXSA 3NVMA 2AJEA 4OT2A 1E7FA 5DBYA 2Z8KA 5GHKA 1E7CA 3NVKA 1E7IA 1N5UA 2BXKA 4J2VA 1BKEA 1TXUA 1MIYA 3JQZA 4LUFA 2OZBB 1E7BA 2GUTA 3MHHB 4GDXA 5GIOA 4N0UD 3V08A 4TQ1A 2BXEA 2BXDA 2VDBA 4ZBRA 3SIVB 2EFDA 4Z9OA 4ZC6A 2BXOA 4JK4A 2LOQA 1VFIA 3FNMA 3H37A 3JRYA 4TQ0A 2E0XA 1E7EA 1SB0A 2CKXA 2E0YA 4LB9A 2BXFA 3ICXA 4L9KA 4DM0A 2XVUA 2BXMA 3VQIA 3SQJA 3H3AA 5BPKA 5IJFA 3PLAA 2V36A 3GQUA 2BXIA 5GINA 4IW1A 1TF0A 4NAWB 4F5TA 4ZBQA 3WHRA 2QHBA 1LOTA 2EFHA 1NT2B 4FK5B 5B5TA 5DQFA 3FWCC 1GNIA 4M70B 3KJLA 4GG2A 3CX9A 4F5SA 1MM8A 2ROHA 5IIHA 4K71A 5IIXA 5ID7A 1O9XA 3M99C 4L8UA 3LU8A 4ZCGA 5ID9A 4E99A 2Z8JA 1IJGA 1HK2A 2DBUA 3WHQA 1E78A 2NNWA 3GA9L 4GDKB 1AO6A 2I2ZA 2BXNA 3BPJA 4LB2A 2I30A 4PO0A 2BX8A 2K0NA 1BJ5A 4D7XA 2OT3A 2DYOA 4FJCB 4OTTA 1KXPD 4HGMB 5GIPA 1MUHA 4BKEA 1E7AA 1HA2A 5IFOA 3FWBC 4EMXA 2EFEA 4HGKA 1MIVA 3A73A 3V03A 4S1YA 4F5VA 4ZBKA 2XVVA 2Z8IA 1MUSA 2DG5A 3MHSB 2AGHB 2BXCA 2VUFA 2BXQA 1HK3A 3GQXA 4C31B 2EFCA 5IJEA 4LUHA 4BY9C 4OR0A 5D7GA 1HK5A 5FUOA 4L9QA 2XW1A 4K2CA 1KDXA 2BXHA 2BXPA 2QM6A 3B9MA 4FIPB 4DHXB 2LQIA 3NMUA 1JNBA 1MA9A 4W4UB 4GDLB 3WHSA 3TDLA
chains in the Genus database with same CATH topology
1KDXA 2AGHB 2LXTA 2K0NA 4D7XA 1SB0A 2LQHA 2LQIA 2GUTA 2LXSA 4I9OA 2KWFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KDX A;  2AGH B;  2LXT A;  2K0N A;  4D7X A;  1SB0 A;  2LQH A;  2LQI A;  2GUT A;  2LXS A;  4I9O A;  2KWF A; 
#chains in the Genus database with same CATH topology
 3LU6 A;  2VUE A;  2XSI A;  1LNS A;  2QMC A;  4G03 A;  3UIV A;  1J78 A;  3W1S A;  1H5W A;  4WA6 B;  2LQH A;  4OTU A;  5IJ5 A;  3KIK A;  1MIW A;  2XVQ A;  5HOZ A;  2XMO A;  3SIU B;  1HK1 A;  1J7E A;  1E7H A;  2KBZ A;  4MBE C;  2BXA A;  3V09 A;  3ECP A;  2DBX A;  2LXT A;  2NQO A;  4IW2 A;  4G01 A;  2BXB A;  4Z69 A;  1GNJ A;  2DBW A;  2XW0 A;  3B9L A;  4ZUX V;  4F5U A;  4I9O A;  2KWF A;  1KW2 A;  2DYM A;  1HK4 A;  1H9Z A;  2YDF A;  4G04 A;  1BM0 A;  1FOU A;  1VZS A;  1UOR A;  3A75 A;  3LU7 A;  4LA0 A;  3G9K D;  2XVW A;  2BXL A;  2BXG A;  1E7G A;  2JUH A;  4N0F D;  4N3Z A;  5IIU A;  3NVI A;  2LXS A;  3NVM A;  2AJE A;  4OT2 A;  1E7F A;  5DBY A;  2Z8K A;  5GHK A;  1E7C A;  3NVK A;  1E7I A;  1N5U A;  2BXK A;  4J2V A;  1BKE A;  1TXU A;  1MIY A;  3JQZ A;  4LUF A;  2OZB B;  1E7B A;  2GUT A;  3MHH B;  4GDX A;  5GIO A;  4N0U D;  3V08 A;  4TQ1 A;  2BXE A;  2BXD A;  2VDB A;  4ZBR A;  3SIV B;  2EFD A;  4Z9O A;  4ZC6 A;  2BXO A;  4JK4 A;  2LOQ A;  1VFI A;  3FNM A;  3H37 A;  3JRY A;  4TQ0 A;  2E0X A;  1E7E A;  1SB0 A;  2CKX A;  2E0Y A;  4LB9 A;  2BXF A;  3ICX A;  4L9K A;  4DM0 A;  2XVU A;  2BXM A;  3VQI A;  3SQJ A;  3H3A A;  5BPK A;  5IJF A;  3PLA A;  2V36 A;  3GQU A;  2BXI A;  5GIN A;  4IW1 A;  1TF0 A;  4NAW B;  4F5T A;  4ZBQ A;  3WHR A;  2QHB A;  1LOT A;  2EFH A;  1NT2 B;  4FK5 B;  5B5T A;  5DQF A;  3FWC C;  1GNI A;  4M70 B;  3KJL A;  4GG2 A;  3CX9 A;  4F5S A;  1MM8 A;  2ROH A;  5IIH A;  4K71 A;  5IIX A;  5ID7 A;  1O9X A;  3M99 C;  4L8U A;  3LU8 A;  4ZCG A;  5ID9 A;  4E99 A;  2Z8J A;  1IJG A;  1HK2 A;  2DBU A;  3WHQ A;  1E78 A;  2NNW A;  3GA9 L;  4GDK B;  1AO6 A;  2I2Z A;  2BXN A;  3BPJ A;  4LB2 A;  2I30 A;  4PO0 A;  2BX8 A;  2K0N A;  1BJ5 A;  4D7X A;  2OT3 A;  2DYO A;  4FJC B;  4OTT A;  1KXP D;  4HGM B;  5GIP A;  1MUH A;  4BKE A;  1E7A A;  1HA2 A;  5IFO A;  3FWB C;  4EMX A;  2EFE A;  4HGK A;  1MIV A;  3A73 A;  3V03 A;  4S1Y A;  4F5V A;  4ZBK A;  2XVV A;  2Z8I A;  1MUS A;  2DG5 A;  3MHS B;  2AGH B;  2BXC A;  2VUF A;  2BXQ A;  1HK3 A;  3GQX A;  4C31 B;  2EFC A;  5IJE A;  4LUH A;  4BY9 C;  4OR0 A;  5D7G A;  1HK5 A;  5FUO A;  4L9Q A;  2XW1 A;  4K2C A;  1KDX A;  2BXH A;  2BXP A;  2QM6 A;  3B9M A;  4FIP B;  4DHX B;  2LQI A;  3NMU A;  1JNB A;  1MA9 A;  4W4U B;  4GDL B;  3WHS A;  3TDL A; 
#chains in the Genus database with same CATH homology
 1KDX A;  2AGH B;  2LXT A;  2K0N A;  4D7X A;  1SB0 A;  2LQH A;  2LQI A;  2GUT A;  2LXS A;  4I9O A;  2KWF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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