4E99A

Human serum albumin complex with perfluorooctane sulfonate potassium
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
567
structure length
554
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural evidence of perfluorooctane sulfonate transport by human serum albumin
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Serum albumin
total genus 226
structure length 554
sequence length 567
ec nomenclature
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A05
4G03A 3JQZA 4S1YA 1E7EA 5ID7A 3B9MA 1HK4A 1GNJA 1N5UA 2BXOA 4N0FD 1E7IA 4L9KA 4F5UA 4ZBRA 2BXGA 4L9QA 3B9LA 4LUFA 2XW0A 3TDLA 1AO6A 5DBYA 2XVUA 3LU7A 1HA2A 1HK1A 5IIXA 4J2VA 5IJ5A 4F5TA 5DQFA 3SQJA 1E7CA 1TF0A 4F5VA 1HK5A 3A73A 5IJFA 1E78A 1BM0A 1E7GA 4K2CA 5ID9A 4LB2A 4HGKA 2I30A 3V09A 1E7FA 2XVWA 2BXKA 1KW2A 2XSIA 1H9ZA 4IW1A 4G04A 4OT2A 2XW1A 4K71A 4HGMB 4BKEA 1E7BA 4LA0A 2XVVA 5GHKA 4LUHA 5IIHA 5FUOA 2BXFA 4PO0A 2I2ZA 4L8UA 3V08A 3V03A 2BXQA 4N0UD 1BKEA 2BXEA 3JRYA 2BXMA 4IW2A 4E99A 2BXLA 2VDBA 5IFOA 5IJEA 1O9XA 4EMXA 1J78A 2BXAA 3UIVA 5HOZA 2BXHA 3LU6A 2BXIA 4F5SA 3LU8A 4OR0A 1BJ5A 4JK4A 1KXPD 1J7EA 1MA9A 1E7HA 2XVQA 2BXNA 1HK3A 4ZBQA 5IIUA 2BXDA 1LOTA 2BX8A 2BXCA 2VUFA 1GNIA 1HK2A 2BXPA 2VUEA 1E7AA 4LB9A 4Z69A 2BXBA 1UORA 2YDFA 3CX9A
chains in the Genus database with same CATH superfamily
4G03A 3JQZA 4S1YA 4ZC6A 1E7EA 5ID7A 3B9MA 3A75A 3VQIA 1HK4A 4N3ZA 1GNJA 1N5UA 5B5TA 3H37A 2BXOA 4N0FD 1TXUA 3ECPA 2QHBA 1MM8A 1E7IA 4FK5B 4L9KA 4F5UA 1KDXA 3M99C 4GDLB 4ZBRA 2BXGA 3GQXA 4L9QA 3B9LA 4LUFA 2XW0A 3TDLA 4GG2A 1AO6A 3NVMA 5DBYA 2XVUA 4FJCB 3LU7A 1HA2A 1HK1A 3WHSA 2Z8KA 4ZUXV 1MUHA 1MUSA 4M70B 5IIXA 4J2VA 5D7GA 5IJ5A 4F5TA 4TQ1A 5DQFA 2AGHB 4D7XA 2QMCA 3G9KD 3SQJA 1E7CA 1TF0A 2LQHA 2K0NA 4F5VA 1HK5A 3A73A 2DBWA 1E78A 1BM0A 4FIPB 5IJFA 1E7GA 1H5WA 4K2CA 5ID9A 4LB2A 4NAWB 4HGKA 2I30A 3V09A 4C31B 5GINA 1E7FA 2OT3A 2XVWA 4MBEC 2BXKA 2LXSA 2QM6A 1KW2A 2XSIA 1H9ZA 4I9OA 1NT2B 4G04A 4IW1A 2JUHA 2XW1A 4K71A 2LXTA 4GDKB 4OTTA 5GIPA 4HGMB 2DG5A 2AJEA 4BKEA 4BY9C 1E7BA 4LA0A 2DBUA 2XVVA 4GDXA 5GHKA 2CKXA 4LUHA 5IIHA 3NVIA 5FUOA 2BXFA 3FNMA 2E0XA 2I2ZA 1VFIA 2V36A 4L8UA 4OT2A 4PO0A 3MHHB 3H3AA 3V08A 2E0YA 2LOQA 2LQIA 3V03A 3MHSB 3GQUA 4Z9OA 1VZSA 2BXQA 4N0UD 1BKEA 2BXEA 3JRYA 2BXMA 4G01A 4IW2A 2XMOA 3SIVB 4TQ0A 4E99A 2NQOA 3ICXA 2BXLA 2VDBA 1MIYA 4ZBKA 5IFOA 1SB0A 5IJEA 3BPJA 1O9XA 3SIUB 2EFDA 4EMXA 1J78A 2BXAA 2Z8IA 2EFHA 3UIVA 2KWFA 2BXHA 5HOZA 3LU6A 2DYMA 2BXIA 3WHRA 4F5SA 3LU8A 4OR0A 4DM0A 3FWCC 2DYOA 4WA6B 3NMUA 5GIOA 3KJLA 1BJ5A 2ROHA 3WHQA 2OZBB 4JK4A 3FWBC 1KXPD 1J7EA 1FOUA 1MA9A 1E7HA 1JNBA 2XVQA 4DHXB 2BXNA 1HK3A 2EFEA 4ZBQA 5IIUA 2BXDA 4W4UB 1LOTA 4OTUA 1IJGA 2KBZA 2NNWA 1MIVA 2BX8A 2BXCA 1MIWA 3NVKA 2VUFA 1GNIA 3CX9A 2DBXA 1HK2A 2EFCA 2BXPA 2GUTA 3W1SA 5BPKA 2VUEA 4ZCGA 2Z8JA 3GA9L 3KIKA 3PLAA 4LB9A 4Z69A 2BXBA 1UORA 1LNSA 2YDFA 1E7AA
chains in the Genus database with same CATH topology
4G03A 3JQZA 4S1YA 4ZC6A 1E7EA 5ID7A 3B9MA 3A75A 3VQIA 1HK4A 4N3ZA 1GNJA 1N5UA 5B5TA 3H37A 2BXOA 4N0FD 1TXUA 2QHBA 1E7IA 4FK5B 4L9KA 4F5UA 3M99C 4GDLB 4ZBRA 2BXGA 3GQXA 4L9QA 3B9LA 4LUFA 2XW0A 3TDLA 4GG2A 1AO6A 3NVMA 5DBYA 2XVUA 4FJCB 3LU7A 1HA2A 1HK1A 3WHSA 2Z8KA 4ZUXV 4M70B 5IIXA 4J2VA 5D7GA 5IJ5A 4F5TA 4TQ1A 5DQFA 2QMCA 3G9KD 3SQJA 1E7CA 1TF0A 4F5VA 1HK5A 3A73A 2DBWA 1E78A 1BM0A 4FIPB 5IJFA 1E7GA 1H5WA 4K2CA 5ID9A 4LB2A 4NAWB 4HGKA 2I30A 3V09A 4C31B 5GINA 1E7FA 2OT3A 2XVWA 4MBEC 2BXKA 2QM6A 1KW2A 2XSIA 1H9ZA 4IW1A 1NT2B 4G04A 4OTTA 2JUHA 2XW1A 4K71A 4OT2A 4GDKB 5GIPA 4HGMB 2DG5A 2AJEA 4BKEA 4BY9C 1E7BA 4LA0A 2DBUA 2XVVA 4GDXA 5GHKA 2CKXA 4LUHA 5IIHA 3NVIA 5FUOA 2BXFA 3FNMA 2E0XA 2I2ZA 1VFIA 2V36A 4L8UA 4PO0A 3MHHB 3H3AA 3V08A 2E0YA 2LOQA 3V03A 3MHSB 3GQUA 4Z9OA 1VZSA 2BXQA 4N0UD 1BKEA 2BXEA 3JRYA 2BXMA 4G01A 4IW2A 2XMOA 3SIVB 4TQ0A 4E99A 2NQOA 3ICXA 2BXLA 2VDBA 1MIYA 4ZBKA 5IFOA 5IJEA 3SIUB 1O9XA 2EFDA 4EMXA 1J78A 2BXAA 2Z8IA 2EFHA 3UIVA 5HOZA 2BXHA 3LU6A 2DYMA 2BXIA 3WHRA 4F5SA 3LU8A 4OR0A 3FWCC 2DYOA 4WA6B 3NMUA 5GIOA 3KJLA 1BJ5A 2ROHA 3WHQA 2OZBB 4JK4A 3FWBC 1KXPD 1J7EA 1FOUA 1MA9A 1E7HA 1JNBA 2XVQA 4DHXB 2BXNA 1HK3A 2EFEA 4ZBQA 5IIUA 2BXDA 4W4UB 1LOTA 4OTUA 1IJGA 2KBZA 2NNWA 1MIVA 2BX8A 2BXCA 1MIWA 3NVKA 2VUFA 1GNIA 3CX9A 2DBXA 1HK2A 2EFCA 2BXPA 3W1SA 5BPKA 2VUEA 4ZCGA 2Z8JA 3GA9L 3KIKA 3PLAA 4LB9A 4Z69A 2BXBA 1UORA 1LNSA 2YDFA 1E7AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G03 A;  3JQZ A;  4S1Y A;  1E7E A;  5ID7 A;  3B9M A;  1HK4 A;  1GNJ A;  1N5U A;  2BXO A;  4N0F D;  1E7I A;  4L9K A;  4F5U A;  4ZBR A;  2BXG A;  4L9Q A;  3B9L A;  4LUF A;  2XW0 A;  3TDL A;  1AO6 A;  5DBY A;  2XVU A;  3LU7 A;  1HA2 A;  1HK1 A;  5IIX A;  4J2V A;  5IJ5 A;  4F5T A;  5DQF A;  3SQJ A;  1E7C A;  1TF0 A;  4F5V A;  1HK5 A;  3A73 A;  5IJF A;  1E78 A;  1BM0 A;  1E7G A;  4K2C A;  5ID9 A;  4LB2 A;  4HGK A;  2I30 A;  3V09 A;  1E7F A;  2XVW A;  2BXK A;  1KW2 A;  2XSI A;  1H9Z A;  4IW1 A;  4G04 A;  4OT2 A;  2XW1 A;  4K71 A;  4HGM B;  4BKE A;  1E7B A;  4LA0 A;  2XVV A;  5GHK A;  4LUH A;  5IIH A;  5FUO A;  2BXF A;  4PO0 A;  2I2Z A;  4L8U A;  3V08 A;  3V03 A;  2BXQ A;  4N0U D;  1BKE A;  2BXE A;  3JRY A;  2BXM A;  4IW2 A;  4E99 A;  2BXL A;  2VDB A;  5IFO A;  5IJE A;  1O9X A;  4EMX A;  1J78 A;  2BXA A;  3UIV A;  5HOZ A;  2BXH A;  3LU6 A;  2BXI A;  4F5S A;  3LU8 A;  4OR0 A;  1BJ5 A;  4JK4 A;  1KXP D;  1J7E A;  1MA9 A;  1E7H A;  2XVQ A;  2BXN A;  1HK3 A;  4ZBQ A;  5IIU A;  2BXD A;  1LOT A;  2BX8 A;  2BXC A;  2VUF A;  1GNI A;  1HK2 A;  2BXP A;  2VUE A;  1E7A A;  4LB9 A;  4Z69 A;  2BXB A;  1UOR A;  2YDF A;  3CX9 A; 
#chains in the Genus database with same CATH topology
 4G03 A;  3JQZ A;  4S1Y A;  4ZC6 A;  1E7E A;  5ID7 A;  3B9M A;  3A75 A;  3VQI A;  1HK4 A;  4N3Z A;  1GNJ A;  1N5U A;  5B5T A;  3H37 A;  2BXO A;  4N0F D;  1TXU A;  3ECP A;  2QHB A;  1MM8 A;  1E7I A;  4FK5 B;  4L9K A;  4F5U A;  1KDX A;  3M99 C;  4GDL B;  4ZBR A;  2BXG A;  3GQX A;  4L9Q A;  3B9L A;  4LUF A;  2XW0 A;  3TDL A;  4GG2 A;  1AO6 A;  3NVM A;  5DBY A;  2XVU A;  4FJC B;  3LU7 A;  1HA2 A;  1HK1 A;  3WHS A;  2Z8K A;  4ZUX V;  1MUH A;  1MUS A;  4M70 B;  5IIX A;  4J2V A;  5D7G A;  5IJ5 A;  4F5T A;  4TQ1 A;  5DQF A;  2AGH B;  4D7X A;  2QMC A;  3G9K D;  3SQJ A;  1E7C A;  1TF0 A;  2LQH A;  2K0N A;  4F5V A;  1HK5 A;  3A73 A;  2DBW A;  1E78 A;  1BM0 A;  4FIP B;  5IJF A;  1E7G A;  1H5W A;  4K2C A;  5ID9 A;  4LB2 A;  4NAW B;  4HGK A;  2I30 A;  3V09 A;  4C31 B;  5GIN A;  1E7F A;  2OT3 A;  2XVW A;  4MBE C;  2BXK A;  2LXS A;  2QM6 A;  1KW2 A;  2XSI A;  1H9Z A;  4I9O A;  1NT2 B;  4G04 A;  4IW1 A;  2JUH A;  2XW1 A;  4K71 A;  2LXT A;  4GDK B;  4OTT A;  5GIP A;  4HGM B;  2DG5 A;  2AJE A;  4BKE A;  4BY9 C;  1E7B A;  4LA0 A;  2DBU A;  2XVV A;  4GDX A;  5GHK A;  2CKX A;  4LUH A;  5IIH A;  3NVI A;  5FUO A;  2BXF A;  3FNM A;  2E0X A;  2I2Z A;  1VFI A;  2V36 A;  4L8U A;  4OT2 A;  4PO0 A;  3MHH B;  3H3A A;  3V08 A;  2E0Y A;  2LOQ A;  2LQI A;  3V03 A;  3MHS B;  3GQU A;  4Z9O A;  1VZS A;  2BXQ A;  4N0U D;  1BKE A;  2BXE A;  3JRY A;  2BXM A;  4G01 A;  4IW2 A;  2XMO A;  3SIV B;  4TQ0 A;  4E99 A;  2NQO A;  3ICX A;  2BXL A;  2VDB A;  1MIY A;  4ZBK A;  5IFO A;  1SB0 A;  5IJE A;  3BPJ A;  1O9X A;  3SIU B;  2EFD A;  4EMX A;  1J78 A;  2BXA A;  2Z8I A;  2EFH A;  3UIV A;  2KWF A;  2BXH A;  5HOZ A;  3LU6 A;  2DYM A;  2BXI A;  3WHR A;  4F5S A;  3LU8 A;  4OR0 A;  4DM0 A;  3FWC C;  2DYO A;  4WA6 B;  3NMU A;  5GIO A;  3KJL A;  1BJ5 A;  2ROH A;  3WHQ A;  2OZB B;  4JK4 A;  3FWB C;  1KXP D;  1J7E A;  1FOU A;  1MA9 A;  1E7H A;  1JNB A;  2XVQ A;  4DHX B;  2BXN A;  1HK3 A;  2EFE A;  4ZBQ A;  5IIU A;  2BXD A;  4W4U B;  1LOT A;  4OTU A;  1IJG A;  2KBZ A;  2NNW A;  1MIV A;  2BX8 A;  2BXC A;  1MIW A;  3NVK A;  2VUF A;  1GNI A;  3CX9 A;  2DBX A;  1HK2 A;  2EFC A;  2BXP A;  2GUT A;  3W1S A;  5BPK A;  2VUE A;  4ZCG A;  2Z8J A;  3GA9 L;  3KIK A;  3PLA A;  4LB9 A;  4Z69 A;  2BXB A;  1UOR A;  1LNS A;  2YDF A;  1E7A A; 
#chains in the Genus database with same CATH homology
 4G03 A;  3JQZ A;  4S1Y A;  4ZC6 A;  1E7E A;  5ID7 A;  3B9M A;  3A75 A;  3VQI A;  1HK4 A;  4N3Z A;  1GNJ A;  1N5U A;  5B5T A;  3H37 A;  2BXO A;  4N0F D;  1TXU A;  2QHB A;  1E7I A;  4FK5 B;  4L9K A;  4F5U A;  3M99 C;  4GDL B;  4ZBR A;  2BXG A;  3GQX A;  4L9Q A;  3B9L A;  4LUF A;  2XW0 A;  3TDL A;  4GG2 A;  1AO6 A;  3NVM A;  5DBY A;  2XVU A;  4FJC B;  3LU7 A;  1HA2 A;  1HK1 A;  3WHS A;  2Z8K A;  4ZUX V;  4M70 B;  5IIX A;  4J2V A;  5D7G A;  5IJ5 A;  4F5T A;  4TQ1 A;  5DQF A;  2QMC A;  3G9K D;  3SQJ A;  1E7C A;  1TF0 A;  4F5V A;  1HK5 A;  3A73 A;  2DBW A;  1E78 A;  1BM0 A;  4FIP B;  5IJF A;  1E7G A;  1H5W A;  4K2C A;  5ID9 A;  4LB2 A;  4NAW B;  4HGK A;  2I30 A;  3V09 A;  4C31 B;  5GIN A;  1E7F A;  2OT3 A;  2XVW A;  4MBE C;  2BXK A;  2QM6 A;  1KW2 A;  2XSI A;  1H9Z A;  4IW1 A;  1NT2 B;  4G04 A;  4OTT A;  2JUH A;  2XW1 A;  4K71 A;  4OT2 A;  4GDK B;  5GIP A;  4HGM B;  2DG5 A;  2AJE A;  4BKE A;  4BY9 C;  1E7B A;  4LA0 A;  2DBU A;  2XVV A;  4GDX A;  5GHK A;  2CKX A;  4LUH A;  5IIH A;  3NVI A;  5FUO A;  2BXF A;  3FNM A;  2E0X A;  2I2Z A;  1VFI A;  2V36 A;  4L8U A;  4PO0 A;  3MHH B;  3H3A A;  3V08 A;  2E0Y A;  2LOQ A;  3V03 A;  3MHS B;  3GQU A;  4Z9O A;  1VZS A;  2BXQ A;  4N0U D;  1BKE A;  2BXE A;  3JRY A;  2BXM A;  4G01 A;  4IW2 A;  2XMO A;  3SIV B;  4TQ0 A;  4E99 A;  2NQO A;  3ICX A;  2BXL A;  2VDB A;  1MIY A;  4ZBK A;  5IFO A;  5IJE A;  3SIU B;  1O9X A;  2EFD A;  4EMX A;  1J78 A;  2BXA A;  2Z8I A;  2EFH A;  3UIV A;  5HOZ A;  2BXH A;  3LU6 A;  2DYM A;  2BXI A;  3WHR A;  4F5S A;  3LU8 A;  4OR0 A;  3FWC C;  2DYO A;  4WA6 B;  3NMU A;  5GIO A;  3KJL A;  1BJ5 A;  2ROH A;  3WHQ A;  2OZB B;  4JK4 A;  3FWB C;  1KXP D;  1J7E A;  1FOU A;  1MA9 A;  1E7H A;  1JNB A;  2XVQ A;  4DHX B;  2BXN A;  1HK3 A;  2EFE A;  4ZBQ A;  5IIU A;  2BXD A;  4W4U B;  1LOT A;  4OTU A;  1IJG A;  2KBZ A;  2NNW A;  1MIV A;  2BX8 A;  2BXC A;  1MIW A;  3NVK A;  2VUF A;  1GNI A;  3CX9 A;  2DBX A;  1HK2 A;  2EFC A;  2BXP A;  3W1S A;  5BPK A;  2VUE A;  4ZCG A;  2Z8J A;  3GA9 L;  3KIK A;  3PLA A;  4LB9 A;  4Z69 A;  2BXB A;  1UOR A;  1LNS A;  2YDF A;  1E7A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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