4E99A

Human serum albumin complex with perfluorooctane sulfonate potassium
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
567
structure length
554
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Serum albumin
publication title Structural evidence of perfluorooctane sulfonate transport by human serum albumin
pubmed doi rcsb
source organism Homo sapiens
total genus 226
structure length 554
sequence length 567
ec nomenclature
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A05
2XSIA 3V08A 5IIHA 4Z69A 4G03A 3V09A 2BXNA 2VDBA 4LUHA 4LA0A 2VUFA 1HK3A 4IW1A 4ZBQA 2BXHA 1TF0A 3V03A 4IW2A 1O9XA 2XVQA 4LB2A 3LU7A 2BX8A 4K2CA 5HOZA 4N0FD 5IJEA 1HK1A 2XVUA 1UORA 1E7BA 5IIUA 1BM0A 2BXLA 1E7CA 5IIXA 4PO0A 4F5SA 3A73A 1E7HA 1E7GA 1E7EA 4L8UA 1E78A 2XW1A 2I2ZA 3LU6A 1BJ5A 3B9LA 1H9ZA 1HK5A 3LU8A 5DQFA 1GNIA 1HK4A 2BXBA 1MA9A 4F5VA 2BXEA 2I30A 3JQZA 1J7EA 1E7AA 1KW2A 2VUEA 4G04A 5DBYA 2XVVA 1BKEA 5GHKA 2BXPA 3TDLA 1N5UA 4OT2A 5IFOA 4L9KA 2BXCA 4K71A 5ID7A 5IJFA 1E7IA 4N0UD 4HGMB 4BKEA 4JK4A 4L9QA 1LOTA 5IJ5A 2BXMA 2BXOA 1J78A 4LB9A 1GNJA 5ID9A 2XW0A 2BXKA 4ZBRA 2BXDA 4S1YA 2BXIA 4J2VA 2BXQA 2XVWA 1E7FA 2BXGA 1HA2A 4E99A 5FUOA 1KXPD 4F5UA 4HGKA 3UIVA 3SQJA 2BXFA 4LUFA 2YDFA 1AO6A 2BXAA 4OR0A 3CX9A 4EMXA 3B9MA 4F5TA 1HK2A 3JRYA
chains in the Genus database with same CATH superfamily
4DM0A 2XSIA 3GA9L 2DBXA 3V08A 5IIHA 4Z69A 4G03A 3V09A 3PLAA 2BXNA 2VDBA 4LUHA 4LA0A 2VUFA 1HK3A 2Z8IA 4IW1A 4ZBQA 2BXHA 3H37A 4OTUA 5BPKA 4I9OA 4D7XA 1TF0A 3V03A 2DBUA 2NQOA 1O9XA 4IW2A 4ZCGA 5B5TA 4ZC6A 3NVMA 2XVQA 3FWBC 4LB2A 3LU7A 2BX8A 5GIOA 4K2CA 4TQ1A 2E0YA 4WA6B 5HOZA 4N0FD 1MUSA 5IJEA 1HK1A 2XVUA 1UORA 3BPJA 1LNSA 1E7BA 2LQIA 2DG5A 1BM0A 3WHRA 4GDKB 5IIUA 2DYOA 2BXLA 2AJEA 2AGHB 2CKXA 2LXSA 2QMCA 2OT3A 1E7CA 4OTTA 5IIXA 4PO0A 4F5SA 3W1SA 3M99C 4GDLB 3A73A 1E7HA 3SIVB 3A75A 1H5WA 3H3AA 1E7GA 1E7EA 4FIPB 4L8UA 1E78A 2KBZA 1FOUA 4GG2A 2NNWA 2XW1A 3FNMA 3SIUB 2KWFA 2I2ZA 4DHXB 3LU6A 1BJ5A 3B9LA 1VZSA 3NVKA 1H9ZA 1HK5A 2Z8KA 3LU8A 1GNIA 1HK4A 5DQFA 2BXBA 1MA9A 4F5VA 2V36A 2BXEA 2I30A 4M70B 3ECPA 3JQZA 3NMUA 1VFIA 2OZBB 1TXUA 1J7EA 1E7AA 1KW2A 2VUEA 4G04A 5DBYA 2XVVA 4FJCB 5GIPA 1BKEA 5GHKA 2QHBA 4ZUXV 2BXPA 1KDXA 2LXTA 3TDLA 1MIVA 2QM6A 1N5UA 2K0NA 4FK5B 4OT2A 5IFOA 4L9KA 1MIWA 2BXCA 2EFDA 4K71A 3KJLA 5ID7A 5IJFA 1E7IA 3G9KD 2GUTA 1IJGA 3GQXA 4HGMB 4N0UD 4Z9OA 4BKEA 4JK4A 4TQ0A 4L9QA 1MM8A 3VQIA 3NVIA 1LOTA 5GINA 5IJ5A 2EFEA 3GQUA 5D7GA 2BXMA 2BXOA 2Z8JA 4N3ZA 1J78A 4LB9A 4C31B 1GNJA 5ID9A 2EFHA 2XW0A 2BXKA 1JNBA 2E0XA 4ZBRA 2BXDA 2EFCA 4S1YA 2BXIA 4J2VA 3MHSB 2BXQA 2XVWA 1E7FA 2BXGA 2JUHA 1HA2A 4E99A 4BY9C 2XMOA 2LOQA 3KIKA 5FUOA 1KXPD 4F5UA 2LQHA 4NAWB 1SB0A 4HGKA 3UIVA 3ICXA 3WHQA 3SQJA 2BXFA 1NT2B 4LUFA 3FWCC 4MBEC 2YDFA 3WHSA 1AO6A 3MHHB 2BXAA 4GDXA 2DBWA 2ROHA 4OR0A 3CX9A 4G01A 4W4UB 1MIYA 1MUHA 4ZBKA 4EMXA 3B9MA 4F5TA 1HK2A 3JRYA 2DYMA
chains in the Genus database with same CATH topology
2XSIA 3GA9L 2DBXA 3V08A 5IIHA 4Z69A 4G03A 3V09A 3PLAA 2BXNA 2VDBA 4LUHA 4LA0A 2VUFA 1HK3A 2Z8IA 4IW1A 4ZBQA 2BXHA 3H37A 4OTUA 5BPKA 1TF0A 3V03A 2DBUA 2NQOA 1O9XA 4IW2A 4ZCGA 5B5TA 4ZC6A 3NVMA 2XVQA 3FWBC 4LB2A 3LU7A 2BX8A 5GIOA 4K2CA 4TQ1A 2E0YA 4WA6B 5HOZA 4N0FD 5IJEA 1HK1A 2XVUA 1UORA 1LNSA 1E7BA 5IIUA 2DG5A 1BM0A 3WHRA 4GDKB 2DYOA 2BXLA 2AJEA 2CKXA 2QMCA 2OT3A 1E7CA 4OTTA 5IIXA 4PO0A 4F5SA 3W1SA 3M99C 4GDLB 3A73A 1E7HA 3SIVB 3A75A 1H5WA 3H3AA 1E7GA 1E7EA 4FIPB 4L8UA 1E78A 2KBZA 1FOUA 4GG2A 2NNWA 2XW1A 3FNMA 3SIUB 2I2ZA 4DHXB 3LU6A 1BJ5A 3B9LA 1VZSA 3NVKA 1H9ZA 1HK5A 2Z8KA 3LU8A 1GNIA 1HK4A 5DQFA 2BXBA 1MA9A 4F5VA 2V36A 2BXEA 2I30A 4M70B 3JQZA 3NMUA 1VFIA 2OZBB 1TXUA 1J7EA 1E7AA 1KW2A 2VUEA 4G04A 5DBYA 2XVVA 4FJCB 5GIPA 1BKEA 5GHKA 2QHBA 4ZUXV 2BXPA 3TDLA 1MIVA 2QM6A 1N5UA 4FK5B 4OT2A 5IFOA 4L9KA 1MIWA 2BXCA 2EFDA 4K71A 3KJLA 5ID7A 5IJFA 1E7IA 3G9KD 4HGMB 1IJGA 3GQXA 4N0UD 4Z9OA 4BKEA 4TQ0A 4JK4A 4L9QA 3VQIA 3NVIA 1LOTA 5GINA 5IJ5A 2EFEA 3GQUA 5D7GA 2BXMA 2BXOA 2Z8JA 4N3ZA 1J78A 4LB9A 4C31B 1GNJA 5ID9A 2EFHA 2XW0A 2BXKA 1JNBA 2E0XA 4ZBRA 2BXDA 2EFCA 4S1YA 2BXIA 4J2VA 3MHSB 2BXQA 2XVWA 1E7FA 2BXGA 2JUHA 1HA2A 4E99A 4BY9C 2XMOA 2LOQA 3KIKA 5FUOA 1KXPD 4F5UA 4NAWB 4HGKA 3UIVA 3ICXA 3WHQA 3SQJA 2BXFA 1NT2B 4LUFA 3FWCC 4MBEC 2YDFA 3WHSA 1AO6A 3MHHB 2BXAA 4GDXA 2DBWA 2ROHA 4OR0A 3CX9A 4G01A 4W4UB 1MIYA 4ZBKA 4EMXA 3B9MA 4F5TA 1HK2A 3JRYA 2DYMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XSI A;  3V08 A;  5IIH A;  4Z69 A;  4G03 A;  3V09 A;  2BXN A;  2VDB A;  4LUH A;  4LA0 A;  2VUF A;  1HK3 A;  4IW1 A;  4ZBQ A;  2BXH A;  1TF0 A;  3V03 A;  4IW2 A;  1O9X A;  2XVQ A;  4LB2 A;  3LU7 A;  2BX8 A;  4K2C A;  5HOZ A;  4N0F D;  5IJE A;  1HK1 A;  2XVU A;  1UOR A;  1E7B A;  5IIU A;  1BM0 A;  2BXL A;  1E7C A;  5IIX A;  4PO0 A;  4F5S A;  3A73 A;  1E7H A;  1E7G A;  1E7E A;  4L8U A;  1E78 A;  2XW1 A;  2I2Z A;  3LU6 A;  1BJ5 A;  3B9L A;  1H9Z A;  1HK5 A;  3LU8 A;  5DQF A;  1GNI A;  1HK4 A;  2BXB A;  1MA9 A;  4F5V A;  2BXE A;  2I30 A;  3JQZ A;  1J7E A;  1E7A A;  1KW2 A;  2VUE A;  4G04 A;  5DBY A;  2XVV A;  1BKE A;  5GHK A;  2BXP A;  3TDL A;  1N5U A;  4OT2 A;  5IFO A;  4L9K A;  2BXC A;  4K71 A;  5ID7 A;  5IJF A;  1E7I A;  4N0U D;  4HGM B;  4BKE A;  4JK4 A;  4L9Q A;  1LOT A;  5IJ5 A;  2BXM A;  2BXO A;  1J78 A;  4LB9 A;  1GNJ A;  5ID9 A;  2XW0 A;  2BXK A;  4ZBR A;  2BXD A;  4S1Y A;  2BXI A;  4J2V A;  2BXQ A;  2XVW A;  1E7F A;  2BXG A;  1HA2 A;  4E99 A;  5FUO A;  1KXP D;  4F5U A;  4HGK A;  3UIV A;  3SQJ A;  2BXF A;  4LUF A;  2YDF A;  1AO6 A;  2BXA A;  4OR0 A;  3CX9 A;  4EMX A;  3B9M A;  4F5T A;  1HK2 A;  3JRY A; 
#chains in the Genus database with same CATH topology
 4DM0 A;  2XSI A;  3GA9 L;  2DBX A;  3V08 A;  5IIH A;  4Z69 A;  4G03 A;  3V09 A;  3PLA A;  2BXN A;  2VDB A;  4LUH A;  4LA0 A;  2VUF A;  1HK3 A;  2Z8I A;  4IW1 A;  4ZBQ A;  2BXH A;  3H37 A;  4OTU A;  5BPK A;  4I9O A;  4D7X A;  1TF0 A;  3V03 A;  2DBU A;  2NQO A;  1O9X A;  4IW2 A;  4ZCG A;  5B5T A;  4ZC6 A;  3NVM A;  2XVQ A;  3FWB C;  4LB2 A;  3LU7 A;  2BX8 A;  5GIO A;  4K2C A;  4TQ1 A;  2E0Y A;  4WA6 B;  5HOZ A;  4N0F D;  1MUS A;  5IJE A;  1HK1 A;  2XVU A;  1UOR A;  3BPJ A;  1LNS A;  1E7B A;  2LQI A;  2DG5 A;  1BM0 A;  3WHR A;  4GDK B;  5IIU A;  2DYO A;  2BXL A;  2AJE A;  2AGH B;  2CKX A;  2LXS A;  2QMC A;  2OT3 A;  1E7C A;  4OTT A;  5IIX A;  4PO0 A;  4F5S A;  3W1S A;  3M99 C;  4GDL B;  3A73 A;  1E7H A;  3SIV B;  3A75 A;  1H5W A;  3H3A A;  1E7G A;  1E7E A;  4FIP B;  4L8U A;  1E78 A;  2KBZ A;  1FOU A;  4GG2 A;  2NNW A;  2XW1 A;  3FNM A;  3SIU B;  2KWF A;  2I2Z A;  4DHX B;  3LU6 A;  1BJ5 A;  3B9L A;  1VZS A;  3NVK A;  1H9Z A;  1HK5 A;  2Z8K A;  3LU8 A;  1GNI A;  1HK4 A;  5DQF A;  2BXB A;  1MA9 A;  4F5V A;  2V36 A;  2BXE A;  2I30 A;  4M70 B;  3ECP A;  3JQZ A;  3NMU A;  1VFI A;  2OZB B;  1TXU A;  1J7E A;  1E7A A;  1KW2 A;  2VUE A;  4G04 A;  5DBY A;  2XVV A;  4FJC B;  5GIP A;  1BKE A;  5GHK A;  2QHB A;  4ZUX V;  2BXP A;  1KDX A;  2LXT A;  3TDL A;  1MIV A;  2QM6 A;  1N5U A;  2K0N A;  4FK5 B;  4OT2 A;  5IFO A;  4L9K A;  1MIW A;  2BXC A;  2EFD A;  4K71 A;  3KJL A;  5ID7 A;  5IJF A;  1E7I A;  3G9K D;  2GUT A;  1IJG A;  3GQX A;  4HGM B;  4N0U D;  4Z9O A;  4BKE A;  4JK4 A;  4TQ0 A;  4L9Q A;  1MM8 A;  3VQI A;  3NVI A;  1LOT A;  5GIN A;  5IJ5 A;  2EFE A;  3GQU A;  5D7G A;  2BXM A;  2BXO A;  2Z8J A;  4N3Z A;  1J78 A;  4LB9 A;  4C31 B;  1GNJ A;  5ID9 A;  2EFH A;  2XW0 A;  2BXK A;  1JNB A;  2E0X A;  4ZBR A;  2BXD A;  2EFC A;  4S1Y A;  2BXI A;  4J2V A;  3MHS B;  2BXQ A;  2XVW A;  1E7F A;  2BXG A;  2JUH A;  1HA2 A;  4E99 A;  4BY9 C;  2XMO A;  2LOQ A;  3KIK A;  5FUO A;  1KXP D;  4F5U A;  2LQH A;  4NAW B;  1SB0 A;  4HGK A;  3UIV A;  3ICX A;  3WHQ A;  3SQJ A;  2BXF A;  1NT2 B;  4LUF A;  3FWC C;  4MBE C;  2YDF A;  3WHS A;  1AO6 A;  3MHH B;  2BXA A;  4GDX A;  2DBW A;  2ROH A;  4OR0 A;  3CX9 A;  4G01 A;  4W4U B;  1MIY A;  1MUH A;  4ZBK A;  4EMX A;  3B9M A;  4F5T A;  1HK2 A;  3JRY A;  2DYM A; 
#chains in the Genus database with same CATH homology
 2XSI A;  3GA9 L;  2DBX A;  3V08 A;  5IIH A;  4Z69 A;  4G03 A;  3V09 A;  3PLA A;  2BXN A;  2VDB A;  4LUH A;  4LA0 A;  2VUF A;  1HK3 A;  2Z8I A;  4IW1 A;  4ZBQ A;  2BXH A;  3H37 A;  4OTU A;  5BPK A;  1TF0 A;  3V03 A;  2DBU A;  2NQO A;  1O9X A;  4IW2 A;  4ZCG A;  5B5T A;  4ZC6 A;  3NVM A;  2XVQ A;  3FWB C;  4LB2 A;  3LU7 A;  2BX8 A;  5GIO A;  4K2C A;  4TQ1 A;  2E0Y A;  4WA6 B;  5HOZ A;  4N0F D;  5IJE A;  1HK1 A;  2XVU A;  1UOR A;  1LNS A;  1E7B A;  5IIU A;  2DG5 A;  1BM0 A;  3WHR A;  4GDK B;  2DYO A;  2BXL A;  2AJE A;  2CKX A;  2QMC A;  2OT3 A;  1E7C A;  4OTT A;  5IIX A;  4PO0 A;  4F5S A;  3W1S A;  3M99 C;  4GDL B;  3A73 A;  1E7H A;  3SIV B;  3A75 A;  1H5W A;  3H3A A;  1E7G A;  1E7E A;  4FIP B;  4L8U A;  1E78 A;  2KBZ A;  1FOU A;  4GG2 A;  2NNW A;  2XW1 A;  3FNM A;  3SIU B;  2I2Z A;  4DHX B;  3LU6 A;  1BJ5 A;  3B9L A;  1VZS A;  3NVK A;  1H9Z A;  1HK5 A;  2Z8K A;  3LU8 A;  1GNI A;  1HK4 A;  5DQF A;  2BXB A;  1MA9 A;  4F5V A;  2V36 A;  2BXE A;  2I30 A;  4M70 B;  3JQZ A;  3NMU A;  1VFI A;  2OZB B;  1TXU A;  1J7E A;  1E7A A;  1KW2 A;  2VUE A;  4G04 A;  5DBY A;  2XVV A;  4FJC B;  5GIP A;  1BKE A;  5GHK A;  2QHB A;  4ZUX V;  2BXP A;  3TDL A;  1MIV A;  2QM6 A;  1N5U A;  4FK5 B;  4OT2 A;  5IFO A;  4L9K A;  1MIW A;  2BXC A;  2EFD A;  4K71 A;  3KJL A;  5ID7 A;  5IJF A;  1E7I A;  3G9K D;  4HGM B;  1IJG A;  3GQX A;  4N0U D;  4Z9O A;  4BKE A;  4TQ0 A;  4JK4 A;  4L9Q A;  3VQI A;  3NVI A;  1LOT A;  5GIN A;  5IJ5 A;  2EFE A;  3GQU A;  5D7G A;  2BXM A;  2BXO A;  2Z8J A;  4N3Z A;  1J78 A;  4LB9 A;  4C31 B;  1GNJ A;  5ID9 A;  2EFH A;  2XW0 A;  2BXK A;  1JNB A;  2E0X A;  4ZBR A;  2BXD A;  2EFC A;  4S1Y A;  2BXI A;  4J2V A;  3MHS B;  2BXQ A;  2XVW A;  1E7F A;  2BXG A;  2JUH A;  1HA2 A;  4E99 A;  4BY9 C;  2XMO A;  2LOQ A;  3KIK A;  5FUO A;  1KXP D;  4F5U A;  4NAW B;  4HGK A;  3UIV A;  3ICX A;  3WHQ A;  3SQJ A;  2BXF A;  1NT2 B;  4LUF A;  3FWC C;  4MBE C;  2YDF A;  3WHS A;  1AO6 A;  3MHH B;  2BXA A;  4GDX A;  2DBW A;  2ROH A;  4OR0 A;  3CX9 A;  4G01 A;  4W4U B;  1MIY A;  4ZBK A;  4EMX A;  3B9M A;  4F5T A;  1HK2 A;  3JRY A;  2DYM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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