4EMXA

Crystal structure analysis of human serum albumin in complex with chloride anions at cryogenic temperature
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
581
structure length
581
Chain Sequence
AHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title New insights on B factors in crystal structure analysis and crystallographic model refinement
rcsb
molecule tags Protein binding
molecule keywords Serum albumin
total genus 226
structure length 581
sequence length 581
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA05
1HK5A 4HGMB 4LUFA 4Z69A 2BXOA 2BXIA 2BXDA 4K2CA 2BXKA 1MA9A 2VUFA 4LB9A 3JQZA 2BXCA 4PO0A 4JK4A 4F5TA 1E78A 1E7CA 4IW2A 4F5UA 1HK1A 4HGKA 2XVUA 1KW2A 3V08A 3JRYA 1HK2A 5IJ5A 3LU8A 4L8UA 2VDBA 4OR0A 4LUHA 3B9LA 2BXFA 3LU6A 4N0FD 2BXLA 1E7FA 2BXAA 5IFOA 3V03A 4G04A 1N5UA 2VUEA 5HOZA 4E99A 2XVWA 3SQJA 3A73A 5IJEA 2XW1A 4LB2A 4ZBQA 1E7HA 4K71A 3B9MA 2BX8A 1UORA 4J2VA 1E7EA 1E7GA 5DBYA 2BXQA 2XVVA 4N0UD 5IIUA 2BXMA 1GNIA 1J78A 2XW0A 5IIXA 4IW1A 4L9KA 4F5VA 4G03A 3LU7A 2BXBA 2BXHA 1HA2A 4OT2A 1E7IA 3UIVA 1TF0A 1BM0A 4L9QA 2XVQA 4BKEA 1O9XA 2I2ZA 3CX9A 1E7BA 1AO6A 4F5SA 5IJFA 1HK4A 2BXEA 5GHKA 5ID7A 2BXGA 1HK3A 1LOTA 3TDLA 4S1YA 1BJ5A 4ZBRA 2I30A 1KXPD 2XSIA 1H9ZA 5DQFA 3V09A 4EMXA 5ID9A 2BXPA 1J7EA 5IIHA 1BKEA 4LA0A 5FUOA 1E7AA 2YDFA 2BXNA 1GNJA
chains in the Genus database with same CATH superfamily
1HK5A 4HGMB 4LUFA 3KIKA 4ZC6A 5GINA 4Z69A 4ZUXV 4OTTA 3VQIA 3ECPA 2BXOA 2BXIA 2DBWA 2KWFA 2BXDA 4TQ1A 2V36A 4K2CA 2BXKA 1MA9A 2VUFA 4LB9A 2DYOA 3MHSB 3JQZA 1MUHA 2BXCA 4PO0A 4JK4A 4F5TA 1E78A 1E7CA 2CKXA 3NVMA 4IW2A 4F5UA 1HK1A 2NQOA 3MHHB 4GDLB 4ZCGA 3BPJA 3WHQA 4HGKA 2XVUA 4FIPB 1KW2A 1VFIA 3V08A 4WA6B 5GIOA 3SIUB 2EFCA 3JRYA 1HK2A 2LQIA 3LU8A 4L8UA 2E0YA 4M70B 2ROHA 2VDBA 4MBEC 2AGHB 4OR0A 1MIVA 4LUHA 3WHRA 3SIVB 3B9LA 1MM8A 2BXFA 3LU6A 3FNMA 4N0FD 2QHBA 5B5TA 4NAWB 5GIPA 2BXLA 1E7FA 2BXAA 3H3AA 5IFOA 1FOUA 4G04A 3V03A 1N5UA 2OZBB 2VUEA 2QM6A 5HOZA 4E99A 2Z8IA 1LNSA 2XVWA 3SQJA 3A73A 4TQ0A 5IJEA 2XW1A 4FK5B 4FJCB 4LB2A 2JUHA 2DBXA 3FWBC 4ZBQA 2Z8JA 3PLAA 2LOQA 1E7HA 4K71A 4N3ZA 3B9MA 4OTUA 4GG2A 4DHXB 2BX8A 1UORA 2AJEA 4J2VA 1E7EA 1E7GA 5D7GA 5DBYA 2BXQA 2XVVA 1TXUA 4N0UD 5IIUA 3G9KD 2BXMA 1GNIA 1MUSA 1J78A 2XW0A 5IIXA 4IW1A 4L9KA 4ZBKA 4F5VA 4G03A 2K0NA 3LU7A 2BXBA 2BXHA 1HA2A 4OT2A 3NVIA 1E7IA 2DG5A 3UIVA 3WHSA 5BPKA 1TF0A 1BM0A 2DBUA 1MIYA 4L9QA 2XVQA 4BKEA 2EFEA 2EFDA 3M99C 1NT2B 1O9XA 2EFHA 2I2ZA 4W4UB 4DM0A 4C31B 3CX9A 1E7BA 1AO6A 3A75A 2LXTA 4BY9C 4F5SA 1VZSA 3GA9L 5IJFA 1HK4A 3NVKA 2BXEA 5GHKA 2E0XA 4GDKB 2QMCA 5ID7A 2BXGA 4G01A 1SB0A 2XMOA 1HK3A 1LOTA 5IJ5A 2LQHA 3TDLA 4S1YA 1BJ5A 2LXSA 2OT3A 4ZBRA 4D7XA 1MIWA 2I30A 1JNBA 1KXPD 2XSIA 2Z8KA 1KDXA 3ICXA 1H9ZA 2KBZA 3FWCC 5DQFA 3V09A 4EMXA 3NMUA 5ID9A 4Z9OA 3GQUA 2BXPA 4I9OA 1J7EA 3GQXA 1IJGA 3KJLA 4GDXA 1BKEA 5IIHA 2DYMA 2NNWA 4LA0A 3H37A 5FUOA 1E7AA 2GUTA 2YDFA 1H5WA 3W1SA 2BXNA 1GNJA
chains in the Genus database with same CATH topology
1HK5A 4HGMB 4LUFA 3KIKA 4ZC6A 5GINA 4Z69A 4ZUXV 4OTTA 3VQIA 2BXOA 2BXIA 2DBWA 2BXDA 4TQ1A 2V36A 4K2CA 2BXKA 1MA9A 2VUFA 4LB9A 2DYOA 3MHSB 3JQZA 2BXCA 4PO0A 4JK4A 4F5TA 1E78A 1E7CA 2CKXA 3NVMA 4IW2A 4F5UA 1HK1A 2NQOA 3MHHB 4GDLB 4ZCGA 3WHQA 4HGKA 2XVUA 4FIPB 1KW2A 1VFIA 3V08A 4WA6B 5GIOA 3SIUB 2EFCA 3JRYA 1HK2A 4M70B 3LU8A 4L8UA 2E0YA 5IJ5A 2ROHA 2VDBA 4MBEC 4OR0A 3WHRA 1MIVA 4LUHA 3SIVB 3B9LA 2BXFA 3LU6A 3FNMA 4N0FD 2QHBA 5B5TA 4NAWB 5GIPA 2BXLA 1E7FA 2BXAA 3H3AA 5IFOA 1FOUA 4G04A 3V03A 1N5UA 2OZBB 2VUEA 2QM6A 5HOZA 4E99A 2Z8IA 1LNSA 2XVWA 3SQJA 3A73A 4TQ0A 5IJEA 2XW1A 4FK5B 4FJCB 4LB2A 2JUHA 2DBXA 3FWBC 4ZBQA 2Z8JA 3PLAA 2LOQA 1E7HA 4K71A 4N3ZA 3B9MA 4OTUA 4GG2A 4DHXB 2BX8A 1UORA 2AJEA 4J2VA 1E7EA 1E7GA 5D7GA 5DBYA 2BXQA 2XVVA 1TXUA 4N0UD 5IIUA 3G9KD 2BXMA 1GNIA 1J78A 2XW0A 5IIXA 4IW1A 4L9KA 4ZBKA 4F5VA 4G03A 3LU7A 2BXBA 2BXHA 1HA2A 4OT2A 3NVIA 1E7IA 2DG5A 3UIVA 3WHSA 5BPKA 1TF0A 1BM0A 2DBUA 1MIYA 4L9QA 2XVQA 4BKEA 2EFEA 2EFDA 3M99C 1NT2B 1O9XA 2EFHA 2I2ZA 4W4UB 4C31B 3CX9A 1E7BA 1AO6A 3A75A 4BY9C 4F5SA 1VZSA 3GA9L 5IJFA 1HK4A 3NVKA 2BXEA 5GHKA 2E0XA 4GDKB 2QMCA 5ID7A 2BXGA 4G01A 2XMOA 1HK3A 1LOTA 3TDLA 4S1YA 1BJ5A 2OT3A 4ZBRA 1MIWA 2I30A 1JNBA 1KXPD 2XSIA 2Z8KA 3ICXA 1H9ZA 2KBZA 3FWCC 5DQFA 3V09A 4EMXA 3NMUA 5ID9A 4Z9OA 3GQUA 2BXPA 1J7EA 3GQXA 1IJGA 3KJLA 4GDXA 1BKEA 5IIHA 2DYMA 2NNWA 4LA0A 3H37A 5FUOA 1E7AA 2YDFA 1H5WA 3W1SA 2BXNA 1GNJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HK5 A;  4HGM B;  4LUF A;  4Z69 A;  2BXO A;  2BXI A;  2BXD A;  4K2C A;  2BXK A;  1MA9 A;  2VUF A;  4LB9 A;  3JQZ A;  2BXC A;  4PO0 A;  4JK4 A;  4F5T A;  1E78 A;  1E7C A;  4IW2 A;  4F5U A;  1HK1 A;  4HGK A;  2XVU A;  1KW2 A;  3V08 A;  3JRY A;  1HK2 A;  5IJ5 A;  3LU8 A;  4L8U A;  2VDB A;  4OR0 A;  4LUH A;  3B9L A;  2BXF A;  3LU6 A;  4N0F D;  2BXL A;  1E7F A;  2BXA A;  5IFO A;  3V03 A;  4G04 A;  1N5U A;  2VUE A;  5HOZ A;  4E99 A;  2XVW A;  3SQJ A;  3A73 A;  5IJE A;  2XW1 A;  4LB2 A;  4ZBQ A;  1E7H A;  4K71 A;  3B9M A;  2BX8 A;  1UOR A;  4J2V A;  1E7E A;  1E7G A;  5DBY A;  2BXQ A;  2XVV A;  4N0U D;  5IIU A;  2BXM A;  1GNI A;  1J78 A;  2XW0 A;  5IIX A;  4IW1 A;  4L9K A;  4F5V A;  4G03 A;  3LU7 A;  2BXB A;  2BXH A;  1HA2 A;  4OT2 A;  1E7I A;  3UIV A;  1TF0 A;  1BM0 A;  4L9Q A;  2XVQ A;  4BKE A;  1O9X A;  2I2Z A;  3CX9 A;  1E7B A;  1AO6 A;  4F5S A;  5IJF A;  1HK4 A;  2BXE A;  5GHK A;  5ID7 A;  2BXG A;  1HK3 A;  1LOT A;  3TDL A;  4S1Y A;  1BJ5 A;  4ZBR A;  2I30 A;  1KXP D;  2XSI A;  1H9Z A;  5DQF A;  3V09 A;  4EMX A;  5ID9 A;  2BXP A;  1J7E A;  5IIH A;  1BKE A;  4LA0 A;  5FUO A;  1E7A A;  2YDF A;  2BXN A;  1GNJ A; 
#chains in the Genus database with same CATH topology
 1HK5 A;  4HGM B;  4LUF A;  3KIK A;  4ZC6 A;  5GIN A;  4Z69 A;  4ZUX V;  4OTT A;  3VQI A;  3ECP A;  2BXO A;  2BXI A;  2DBW A;  2KWF A;  2BXD A;  4TQ1 A;  2V36 A;  4K2C A;  2BXK A;  1MA9 A;  2VUF A;  4LB9 A;  2DYO A;  3MHS B;  3JQZ A;  1MUH A;  2BXC A;  4PO0 A;  4JK4 A;  4F5T A;  1E78 A;  1E7C A;  2CKX A;  3NVM A;  4IW2 A;  4F5U A;  1HK1 A;  2NQO A;  3MHH B;  4GDL B;  4ZCG A;  3BPJ A;  3WHQ A;  4HGK A;  2XVU A;  4FIP B;  1KW2 A;  1VFI A;  3V08 A;  4WA6 B;  5GIO A;  3SIU B;  2EFC A;  3JRY A;  1HK2 A;  2LQI A;  3LU8 A;  4L8U A;  2E0Y A;  4M70 B;  2ROH A;  2VDB A;  4MBE C;  2AGH B;  4OR0 A;  1MIV A;  4LUH A;  3WHR A;  3SIV B;  3B9L A;  1MM8 A;  2BXF A;  3LU6 A;  3FNM A;  4N0F D;  2QHB A;  5B5T A;  4NAW B;  5GIP A;  2BXL A;  1E7F A;  2BXA A;  3H3A A;  5IFO A;  1FOU A;  4G04 A;  3V03 A;  1N5U A;  2OZB B;  2VUE A;  2QM6 A;  5HOZ A;  4E99 A;  2Z8I A;  1LNS A;  2XVW A;  3SQJ A;  3A73 A;  4TQ0 A;  5IJE A;  2XW1 A;  4FK5 B;  4FJC B;  4LB2 A;  2JUH A;  2DBX A;  3FWB C;  4ZBQ A;  2Z8J A;  3PLA A;  2LOQ A;  1E7H A;  4K71 A;  4N3Z A;  3B9M A;  4OTU A;  4GG2 A;  4DHX B;  2BX8 A;  1UOR A;  2AJE A;  4J2V A;  1E7E A;  1E7G A;  5D7G A;  5DBY A;  2BXQ A;  2XVV A;  1TXU A;  4N0U D;  5IIU A;  3G9K D;  2BXM A;  1GNI A;  1MUS A;  1J78 A;  2XW0 A;  5IIX A;  4IW1 A;  4L9K A;  4ZBK A;  4F5V A;  4G03 A;  2K0N A;  3LU7 A;  2BXB A;  2BXH A;  1HA2 A;  4OT2 A;  3NVI A;  1E7I A;  2DG5 A;  3UIV A;  3WHS A;  5BPK A;  1TF0 A;  1BM0 A;  2DBU A;  1MIY A;  4L9Q A;  2XVQ A;  4BKE A;  2EFE A;  2EFD A;  3M99 C;  1NT2 B;  1O9X A;  2EFH A;  2I2Z A;  4W4U B;  4DM0 A;  4C31 B;  3CX9 A;  1E7B A;  1AO6 A;  3A75 A;  2LXT A;  4BY9 C;  4F5S A;  1VZS A;  3GA9 L;  5IJF A;  1HK4 A;  3NVK A;  2BXE A;  5GHK A;  2E0X A;  4GDK B;  2QMC A;  5ID7 A;  2BXG A;  4G01 A;  1SB0 A;  2XMO A;  1HK3 A;  1LOT A;  5IJ5 A;  2LQH A;  3TDL A;  4S1Y A;  1BJ5 A;  2LXS A;  2OT3 A;  4ZBR A;  4D7X A;  1MIW A;  2I30 A;  1JNB A;  1KXP D;  2XSI A;  2Z8K A;  1KDX A;  3ICX A;  1H9Z A;  2KBZ A;  3FWC C;  5DQF A;  3V09 A;  4EMX A;  3NMU A;  5ID9 A;  4Z9O A;  3GQU A;  2BXP A;  4I9O A;  1J7E A;  3GQX A;  1IJG A;  3KJL A;  4GDX A;  1BKE A;  5IIH A;  2DYM A;  2NNW A;  4LA0 A;  3H37 A;  5FUO A;  1E7A A;  2GUT A;  2YDF A;  1H5W A;  3W1S A;  2BXN A;  1GNJ A; 
#chains in the Genus database with same CATH homology
 1HK5 A;  4HGM B;  4LUF A;  3KIK A;  4ZC6 A;  5GIN A;  4Z69 A;  4ZUX V;  4OTT A;  3VQI A;  2BXO A;  2BXI A;  2DBW A;  2BXD A;  4TQ1 A;  2V36 A;  4K2C A;  2BXK A;  1MA9 A;  2VUF A;  4LB9 A;  2DYO A;  3MHS B;  3JQZ A;  2BXC A;  4PO0 A;  4JK4 A;  4F5T A;  1E78 A;  1E7C A;  2CKX A;  3NVM A;  4IW2 A;  4F5U A;  1HK1 A;  2NQO A;  3MHH B;  4GDL B;  4ZCG A;  3WHQ A;  4HGK A;  2XVU A;  4FIP B;  1KW2 A;  1VFI A;  3V08 A;  4WA6 B;  5GIO A;  3SIU B;  2EFC A;  3JRY A;  1HK2 A;  4M70 B;  3LU8 A;  4L8U A;  2E0Y A;  5IJ5 A;  2ROH A;  2VDB A;  4MBE C;  4OR0 A;  3WHR A;  1MIV A;  4LUH A;  3SIV B;  3B9L A;  2BXF A;  3LU6 A;  3FNM A;  4N0F D;  2QHB A;  5B5T A;  4NAW B;  5GIP A;  2BXL A;  1E7F A;  2BXA A;  3H3A A;  5IFO A;  1FOU A;  4G04 A;  3V03 A;  1N5U A;  2OZB B;  2VUE A;  2QM6 A;  5HOZ A;  4E99 A;  2Z8I A;  1LNS A;  2XVW A;  3SQJ A;  3A73 A;  4TQ0 A;  5IJE A;  2XW1 A;  4FK5 B;  4FJC B;  4LB2 A;  2JUH A;  2DBX A;  3FWB C;  4ZBQ A;  2Z8J A;  3PLA A;  2LOQ A;  1E7H A;  4K71 A;  4N3Z A;  3B9M A;  4OTU A;  4GG2 A;  4DHX B;  2BX8 A;  1UOR A;  2AJE A;  4J2V A;  1E7E A;  1E7G A;  5D7G A;  5DBY A;  2BXQ A;  2XVV A;  1TXU A;  4N0U D;  5IIU A;  3G9K D;  2BXM A;  1GNI A;  1J78 A;  2XW0 A;  5IIX A;  4IW1 A;  4L9K A;  4ZBK A;  4F5V A;  4G03 A;  3LU7 A;  2BXB A;  2BXH A;  1HA2 A;  4OT2 A;  3NVI A;  1E7I A;  2DG5 A;  3UIV A;  3WHS A;  5BPK A;  1TF0 A;  1BM0 A;  2DBU A;  1MIY A;  4L9Q A;  2XVQ A;  4BKE A;  2EFE A;  2EFD A;  3M99 C;  1NT2 B;  1O9X A;  2EFH A;  2I2Z A;  4W4U B;  4C31 B;  3CX9 A;  1E7B A;  1AO6 A;  3A75 A;  4BY9 C;  4F5S A;  1VZS A;  3GA9 L;  5IJF A;  1HK4 A;  3NVK A;  2BXE A;  5GHK A;  2E0X A;  4GDK B;  2QMC A;  5ID7 A;  2BXG A;  4G01 A;  2XMO A;  1HK3 A;  1LOT A;  3TDL A;  4S1Y A;  1BJ5 A;  2OT3 A;  4ZBR A;  1MIW A;  2I30 A;  1JNB A;  1KXP D;  2XSI A;  2Z8K A;  3ICX A;  1H9Z A;  2KBZ A;  3FWC C;  5DQF A;  3V09 A;  4EMX A;  3NMU A;  5ID9 A;  4Z9O A;  3GQU A;  2BXP A;  1J7E A;  3GQX A;  1IJG A;  3KJL A;  4GDX A;  1BKE A;  5IIH A;  2DYM A;  2NNW A;  4LA0 A;  3H37 A;  5FUO A;  1E7A A;  2YDF A;  1H5W A;  3W1S A;  2BXN A;  1GNJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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