4EMXA

Crystal structure analysis of human serum albumin in complex with chloride anions at cryogenic temperature
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
581
structure length
581
Chain Sequence
AHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
molecule keywords Serum albumin
publication title New insights on B factors in crystal structure analysis and crystallographic model refinement
rcsb
total genus 226
structure length 581
sequence length 581
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4emxA05
2BXPA 4F5UA 4G03A 1E7FA 5DBYA 4IW1A 4JK4A 4N0FD 5FUOA 3CX9A 4LA0A 2XVWA 1MA9A 4G04A 1J7EA 4HGKA 2BXLA 3V03A 5ID7A 4PO0A 3A73A 2BXCA 1GNIA 1N5UA 3TDLA 4F5TA 4LUFA 1HK1A 4F5SA 4Z69A 3JRYA 2BXDA 1E7IA 4L8UA 5IFOA 4LB9A 1E7CA 3B9LA 4L9QA 1HK3A 4F5VA 1GNJA 1E7GA 2I30A 2BXIA 3SQJA 3LU6A 2BXQA 1BM0A 4OR0A 2BXEA 5IIHA 1HA2A 1AO6A 2BXKA 3LU7A 2BXGA 5ID9A 4E99A 2VDBA 1E78A 1BJ5A 4IW2A 4LB2A 2XW0A 4K2CA 5IJFA 1E7HA 2XVQA 2XW1A 5IJEA 2BX8A 5IJ5A 3UIVA 5IIUA 2BXHA 1O9XA 2BXFA 2XVUA 1HK5A 4HGMB 1HK2A 2BXMA 1E7AA 2BXAA 4LUHA 2VUFA 4L9KA 5DQFA 2VUEA 3B9MA 4BKEA 4N0UD 4OT2A 2XVVA 1J78A 2YDFA 3LU8A 1E7BA 1HK4A 1KW2A 2BXNA 3V09A 2XSIA 4ZBQA 1E7EA 3V08A 5IIXA 1BKEA 2I2ZA 4S1YA 5HOZA 4J2VA 1KXPD 1TF0A 5GHKA 1UORA 1H9ZA 4EMXA 4K71A 2BXBA 3JQZA 2BXOA 1LOTA 4ZBRA
chains in the Genus database with same CATH superfamily
1LNSA 2BXPA 4F5UA 4G03A 1IJGA 2AJEA 1E7FA 5DBYA 2OZBB 1MUSA 2EFCA 3KJLA 4IW1A 4JK4A 4N0FD 5FUOA 2EFDA 3CX9A 4LA0A 3NMUA 2XVWA 2V36A 1MA9A 4G04A 1J7EA 4HGKA 2BXLA 3V03A 3G9KD 4PO0A 5ID7A 2DYMA 3FWCC 3A73A 1VFIA 1MIYA 2BXCA 2OT3A 2ROHA 4TQ1A 1GNIA 3GQUA 1N5UA 2EFHA 3KIKA 2DG5A 3TDLA 4LUFA 1HK1A 4F5TA 3BPJA 4F5SA 4Z69A 3JRYA 2DBXA 2BXDA 4G01A 1MIVA 1E7IA 2LOQA 4L8UA 4LB9A 5IFOA 1E7CA 3GQXA 3B9LA 4L9QA 1HK3A 4ZUXV 2KBZA 2Z8KA 4F5VA 1MUHA 1GNJA 1E7GA 2I30A 2BXIA 3SQJA 3LU6A 2BXQA 1BM0A 1VZSA 4OR0A 2BXEA 4NAWB 4OTTA 2EFEA 2KWFA 5IIHA 1NT2B 1HA2A 2K0NA 1AO6A 1MM8A 2BXKA 3LU7A 2BXGA 5GINA 4MBEC 4OTUA 5ID9A 2NNWA 4E99A 2NQOA 2VDBA 2E0XA 1E78A 1BJ5A 3SIUB 2Z8JA 4IW2A 5GIPA 3A75A 4LB2A 2DBUA 3ECPA 1H5WA 2QMCA 2XW0A 4K2CA 5IJFA 1E7HA 2XVQA 2XW1A 2LXTA 4M70B 3NVIA 5IJEA 1TXUA 2DBWA 3FNMA 1FOUA 4TQ0A 2BX8A 2Z8IA 5IJ5A 4FIPB 1KDXA 3UIVA 3NVKA 5IIUA 2BXHA 1O9XA 2BXFA 4GDLB 4ZC6A 3WHSA 2XVUA 1HK5A 4HGMB 4DHXB 3H37A 3W1SA 2QM6A 1HK2A 2BXMA 1E7AA 2JUHA 5B5TA 4I9OA 2BXAA 4LUHA 4ZCGA 2DYOA 2VUFA 4ZBKA 2E0YA 4L9KA 5DQFA 2AGHB 1MIWA 2VUEA 3B9MA 4Z9OA 4FK5B 4BKEA 3NVMA 4N0UD 4OT2A 2XVVA 1J78A 2GUTA 2YDFA 3LU8A 5BPKA 4DM0A 1E7BA 3H3AA 1HK4A 1KW2A 2BXNA 4GG2A 3V09A 3WHRA 3M99C 2LQIA 4FJCB 4BY9C 2XSIA 4ZBQA 1E7EA 4N3ZA 3V08A 2LXSA 5IIXA 1BKEA 2I2ZA 4S1YA 5HOZA 4J2VA 2QHBA 1KXPD 4GDKB 1TF0A 2XMOA 4D7XA 5GHKA 1SB0A 1UORA 1H9ZA 2LQHA 4W4UB 3WHQA 2CKXA 3GA9L 5GIOA 3MHSB 4K71A 4EMXA 4GDXA 2BXBA 4C31B 3JQZA 4WA6B 3VQIA 1JNBA 3ICXA 3MHHB 2BXOA 1LOTA 3FWBC 5D7GA 4ZBRA 3SIVB 3PLAA
chains in the Genus database with same CATH topology
1LNSA 2BXPA 4F5UA 4G03A 1IJGA 2AJEA 1E7FA 5DBYA 2OZBB 2EFCA 3KJLA 4IW1A 4JK4A 4N0FD 5FUOA 2EFDA 3CX9A 4LA0A 3NMUA 2XVWA 2V36A 1MA9A 4G04A 1J7EA 4HGKA 2BXLA 3V03A 3G9KD 4PO0A 5ID7A 2DYMA 3FWCC 3A73A 1VFIA 1MIYA 2BXCA 2OT3A 2ROHA 4TQ1A 1GNIA 3GQUA 1N5UA 2EFHA 3KIKA 2DG5A 3TDLA 4LUFA 1HK1A 4F5TA 4F5SA 4Z69A 3JRYA 2DBXA 2BXDA 4G01A 1MIVA 1E7IA 2LOQA 4L8UA 4LB9A 5IFOA 1E7CA 3GQXA 3B9LA 4L9QA 1HK3A 4ZUXV 2KBZA 2Z8KA 4F5VA 1GNJA 1E7GA 2I30A 2BXIA 3SQJA 3LU6A 2BXQA 1BM0A 1VZSA 4OR0A 2BXEA 4NAWB 4OTTA 2EFEA 5IIHA 1NT2B 1HA2A 1AO6A 2BXKA 3LU7A 2BXGA 5GINA 4MBEC 4OTUA 5ID9A 2NNWA 4E99A 2NQOA 2VDBA 2E0XA 1E78A 1BJ5A 3SIUB 2Z8JA 4IW2A 5GIPA 3A75A 4LB2A 2DBUA 1H5WA 2QMCA 2XW0A 4K2CA 5IJFA 1E7HA 2XVQA 2XW1A 4M70B 3NVIA 5IJEA 1TXUA 2DBWA 3FNMA 1FOUA 4TQ0A 2BX8A 2Z8IA 5IJ5A 4FIPB 3UIVA 3NVKA 5IIUA 2BXHA 1O9XA 2BXFA 4GDLB 4ZC6A 3WHSA 2XVUA 1HK5A 4HGMB 4DHXB 3H37A 3W1SA 2QM6A 1HK2A 2BXMA 1E7AA 2JUHA 5B5TA 2BXAA 4LUHA 4ZCGA 2DYOA 2VUFA 4ZBKA 2E0YA 4L9KA 5DQFA 1MIWA 2VUEA 3B9MA 4Z9OA 4FK5B 4BKEA 3NVMA 4N0UD 4OT2A 2XVVA 1J78A 2YDFA 3LU8A 5BPKA 1E7BA 3H3AA 1HK4A 1KW2A 2BXNA 4GG2A 3V09A 3WHRA 3M99C 4FJCB 4BY9C 2XSIA 4ZBQA 1E7EA 4N3ZA 3V08A 5IIXA 1BKEA 2I2ZA 4S1YA 5HOZA 4J2VA 2QHBA 1KXPD 4GDKB 1TF0A 2XMOA 5GHKA 1UORA 1H9ZA 4W4UB 3WHQA 2CKXA 3GA9L 5GIOA 3MHSB 4K71A 4EMXA 4GDXA 2BXBA 4C31B 3JQZA 4WA6B 3VQIA 1JNBA 3ICXA 3MHHB 2BXOA 1LOTA 3FWBC 5D7GA 4ZBRA 3SIVB 3PLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXP A;  4F5U A;  4G03 A;  1E7F A;  5DBY A;  4IW1 A;  4JK4 A;  4N0F D;  5FUO A;  3CX9 A;  4LA0 A;  2XVW A;  1MA9 A;  4G04 A;  1J7E A;  4HGK A;  2BXL A;  3V03 A;  5ID7 A;  4PO0 A;  3A73 A;  2BXC A;  1GNI A;  1N5U A;  3TDL A;  4F5T A;  4LUF A;  1HK1 A;  4F5S A;  4Z69 A;  3JRY A;  2BXD A;  1E7I A;  4L8U A;  5IFO A;  4LB9 A;  1E7C A;  3B9L A;  4L9Q A;  1HK3 A;  4F5V A;  1GNJ A;  1E7G A;  2I30 A;  2BXI A;  3SQJ A;  3LU6 A;  2BXQ A;  1BM0 A;  4OR0 A;  2BXE A;  5IIH A;  1HA2 A;  1AO6 A;  2BXK A;  3LU7 A;  2BXG A;  5ID9 A;  4E99 A;  2VDB A;  1E78 A;  1BJ5 A;  4IW2 A;  4LB2 A;  2XW0 A;  4K2C A;  5IJF A;  1E7H A;  2XVQ A;  2XW1 A;  5IJE A;  2BX8 A;  5IJ5 A;  3UIV A;  5IIU A;  2BXH A;  1O9X A;  2BXF A;  2XVU A;  1HK5 A;  4HGM B;  1HK2 A;  2BXM A;  1E7A A;  2BXA A;  4LUH A;  2VUF A;  4L9K A;  5DQF A;  2VUE A;  3B9M A;  4BKE A;  4N0U D;  4OT2 A;  2XVV A;  1J78 A;  2YDF A;  3LU8 A;  1E7B A;  1HK4 A;  1KW2 A;  2BXN A;  3V09 A;  2XSI A;  4ZBQ A;  1E7E A;  3V08 A;  5IIX A;  1BKE A;  2I2Z A;  4S1Y A;  5HOZ A;  4J2V A;  1KXP D;  1TF0 A;  5GHK A;  1UOR A;  1H9Z A;  4EMX A;  4K71 A;  2BXB A;  3JQZ A;  2BXO A;  1LOT A;  4ZBR A; 
#chains in the Genus database with same CATH topology
 1LNS A;  2BXP A;  4F5U A;  4G03 A;  1IJG A;  2AJE A;  1E7F A;  5DBY A;  2OZB B;  1MUS A;  2EFC A;  3KJL A;  4IW1 A;  4JK4 A;  4N0F D;  5FUO A;  2EFD A;  3CX9 A;  4LA0 A;  3NMU A;  2XVW A;  2V36 A;  1MA9 A;  4G04 A;  1J7E A;  4HGK A;  2BXL A;  3V03 A;  3G9K D;  4PO0 A;  5ID7 A;  2DYM A;  3FWC C;  3A73 A;  1VFI A;  1MIY A;  2BXC A;  2OT3 A;  2ROH A;  4TQ1 A;  1GNI A;  3GQU A;  1N5U A;  2EFH A;  3KIK A;  2DG5 A;  3TDL A;  4LUF A;  1HK1 A;  4F5T A;  3BPJ A;  4F5S A;  4Z69 A;  3JRY A;  2DBX A;  2BXD A;  4G01 A;  1MIV A;  1E7I A;  2LOQ A;  4L8U A;  4LB9 A;  5IFO A;  1E7C A;  3GQX A;  3B9L A;  4L9Q A;  1HK3 A;  4ZUX V;  2KBZ A;  2Z8K A;  4F5V A;  1MUH A;  1GNJ A;  1E7G A;  2I30 A;  2BXI A;  3SQJ A;  3LU6 A;  2BXQ A;  1BM0 A;  1VZS A;  4OR0 A;  2BXE A;  4NAW B;  4OTT A;  2EFE A;  2KWF A;  5IIH A;  1NT2 B;  1HA2 A;  2K0N A;  1AO6 A;  1MM8 A;  2BXK A;  3LU7 A;  2BXG A;  5GIN A;  4MBE C;  4OTU A;  5ID9 A;  2NNW A;  4E99 A;  2NQO A;  2VDB A;  2E0X A;  1E78 A;  1BJ5 A;  3SIU B;  2Z8J A;  4IW2 A;  5GIP A;  3A75 A;  4LB2 A;  2DBU A;  3ECP A;  1H5W A;  2QMC A;  2XW0 A;  4K2C A;  5IJF A;  1E7H A;  2XVQ A;  2XW1 A;  2LXT A;  4M70 B;  3NVI A;  5IJE A;  1TXU A;  2DBW A;  3FNM A;  1FOU A;  4TQ0 A;  2BX8 A;  2Z8I A;  5IJ5 A;  4FIP B;  1KDX A;  3UIV A;  3NVK A;  5IIU A;  2BXH A;  1O9X A;  2BXF A;  4GDL B;  4ZC6 A;  3WHS A;  2XVU A;  1HK5 A;  4HGM B;  4DHX B;  3H37 A;  3W1S A;  2QM6 A;  1HK2 A;  2BXM A;  1E7A A;  2JUH A;  5B5T A;  4I9O A;  2BXA A;  4LUH A;  4ZCG A;  2DYO A;  2VUF A;  4ZBK A;  2E0Y A;  4L9K A;  5DQF A;  2AGH B;  1MIW A;  2VUE A;  3B9M A;  4Z9O A;  4FK5 B;  4BKE A;  3NVM A;  4N0U D;  4OT2 A;  2XVV A;  1J78 A;  2GUT A;  2YDF A;  3LU8 A;  5BPK A;  4DM0 A;  1E7B A;  3H3A A;  1HK4 A;  1KW2 A;  2BXN A;  4GG2 A;  3V09 A;  3WHR A;  3M99 C;  2LQI A;  4FJC B;  4BY9 C;  2XSI A;  4ZBQ A;  1E7E A;  4N3Z A;  3V08 A;  2LXS A;  5IIX A;  1BKE A;  2I2Z A;  4S1Y A;  5HOZ A;  4J2V A;  2QHB A;  1KXP D;  4GDK B;  1TF0 A;  2XMO A;  4D7X A;  5GHK A;  1SB0 A;  1UOR A;  1H9Z A;  2LQH A;  4W4U B;  3WHQ A;  2CKX A;  3GA9 L;  5GIO A;  3MHS B;  4K71 A;  4EMX A;  4GDX A;  2BXB A;  4C31 B;  3JQZ A;  4WA6 B;  3VQI A;  1JNB A;  3ICX A;  3MHH B;  2BXO A;  1LOT A;  3FWB C;  5D7G A;  4ZBR A;  3SIV B;  3PLA A; 
#chains in the Genus database with same CATH homology
 1LNS A;  2BXP A;  4F5U A;  4G03 A;  1IJG A;  2AJE A;  1E7F A;  5DBY A;  2OZB B;  2EFC A;  3KJL A;  4IW1 A;  4JK4 A;  4N0F D;  5FUO A;  2EFD A;  3CX9 A;  4LA0 A;  3NMU A;  2XVW A;  2V36 A;  1MA9 A;  4G04 A;  1J7E A;  4HGK A;  2BXL A;  3V03 A;  3G9K D;  4PO0 A;  5ID7 A;  2DYM A;  3FWC C;  3A73 A;  1VFI A;  1MIY A;  2BXC A;  2OT3 A;  2ROH A;  4TQ1 A;  1GNI A;  3GQU A;  1N5U A;  2EFH A;  3KIK A;  2DG5 A;  3TDL A;  4LUF A;  1HK1 A;  4F5T A;  4F5S A;  4Z69 A;  3JRY A;  2DBX A;  2BXD A;  4G01 A;  1MIV A;  1E7I A;  2LOQ A;  4L8U A;  4LB9 A;  5IFO A;  1E7C A;  3GQX A;  3B9L A;  4L9Q A;  1HK3 A;  4ZUX V;  2KBZ A;  2Z8K A;  4F5V A;  1GNJ A;  1E7G A;  2I30 A;  2BXI A;  3SQJ A;  3LU6 A;  2BXQ A;  1BM0 A;  1VZS A;  4OR0 A;  2BXE A;  4NAW B;  4OTT A;  2EFE A;  5IIH A;  1NT2 B;  1HA2 A;  1AO6 A;  2BXK A;  3LU7 A;  2BXG A;  5GIN A;  4MBE C;  4OTU A;  5ID9 A;  2NNW A;  4E99 A;  2NQO A;  2VDB A;  2E0X A;  1E78 A;  1BJ5 A;  3SIU B;  2Z8J A;  4IW2 A;  5GIP A;  3A75 A;  4LB2 A;  2DBU A;  1H5W A;  2QMC A;  2XW0 A;  4K2C A;  5IJF A;  1E7H A;  2XVQ A;  2XW1 A;  4M70 B;  3NVI A;  5IJE A;  1TXU A;  2DBW A;  3FNM A;  1FOU A;  4TQ0 A;  2BX8 A;  2Z8I A;  5IJ5 A;  4FIP B;  3UIV A;  3NVK A;  5IIU A;  2BXH A;  1O9X A;  2BXF A;  4GDL B;  4ZC6 A;  3WHS A;  2XVU A;  1HK5 A;  4HGM B;  4DHX B;  3H37 A;  3W1S A;  2QM6 A;  1HK2 A;  2BXM A;  1E7A A;  2JUH A;  5B5T A;  2BXA A;  4LUH A;  4ZCG A;  2DYO A;  2VUF A;  4ZBK A;  2E0Y A;  4L9K A;  5DQF A;  1MIW A;  2VUE A;  3B9M A;  4Z9O A;  4FK5 B;  4BKE A;  3NVM A;  4N0U D;  4OT2 A;  2XVV A;  1J78 A;  2YDF A;  3LU8 A;  5BPK A;  1E7B A;  3H3A A;  1HK4 A;  1KW2 A;  2BXN A;  4GG2 A;  3V09 A;  3WHR A;  3M99 C;  4FJC B;  4BY9 C;  2XSI A;  4ZBQ A;  1E7E A;  4N3Z A;  3V08 A;  5IIX A;  1BKE A;  2I2Z A;  4S1Y A;  5HOZ A;  4J2V A;  2QHB A;  1KXP D;  4GDK B;  1TF0 A;  2XMO A;  5GHK A;  1UOR A;  1H9Z A;  4W4U B;  3WHQ A;  2CKX A;  3GA9 L;  5GIO A;  3MHS B;  4K71 A;  4EMX A;  4GDX A;  2BXB A;  4C31 B;  3JQZ A;  4WA6 B;  3VQI A;  1JNB A;  3ICX A;  3MHH B;  2BXO A;  1LOT A;  3FWB C;  5D7G A;  4ZBR A;  3SIV B;  3PLA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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