4HGMB

Shark ignar variable domain
Total Genus 173
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
sequence length
489
structure length
478
Chain Sequence
KSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVAEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCSLVNRRPCFSALE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis.
pubmed doi rcsb
molecule tags Immune system
source organism Squalus acanthias
molecule keywords Shark V-NAR
total genus 173
structure length 478
sequence length 489
ec nomenclature
pdb deposition date 2012-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4hgmB02
1E7CA 1E7FA 1LOTA 3JQZA 2YDFA 4IW2A 2BXIA 5IIHA 3B9MA 1UORA 5DQFA 4LUFA 3CX9A 2BXCA 4N0UD 4S1YA 1E7EA 4J2VA 4LA0A 1H9ZA 2BXQA 1E7AA 4F5VA 1GNIA 3UIVA 2I2ZA 1HK2A 2XVVA 2BXMA 1E78A 4JK4A 2BXFA 2XVQA 2BXBA 2XW1A 5IJFA 2BXOA 4ZBQA 2XVUA 3LU8A 4BKEA 1KXPD 4LB9A 4L9QA 5IIUA 3LU6A 4G03A 4EMXA 1MA9A 5IIXA 1E7IA 4F5UA 4L8UA 2BXDA 5ID7A 3V03A 2VDBA 4HGKA 2XSIA 5HOZA 1N5UA 2BXGA 1HK1A 3A73A 1E7GA 4OT2A 1KW2A 4PO0A 1BKEA 4L9KA 4LUHA 4K71A 4N0FD 2I30A 2BXHA 4OR0A 2BXNA 2BXKA 4K2CA 2BXLA 2BXEA 1BJ5A 5FUOA 2BX8A 5IJ5A 3LU7A 4Z69A 1HK4A 2VUFA 1HA2A 4HGMB 1TF0A 3JRYA 5IFOA 1BM0A 4F5SA 1HK3A 4G04A 1O9XA 5GHKA 3SQJA 4E99A 1GNJA 5ID9A 3TDLA 2XVWA 1J78A 1E7BA 1E7HA 1J7EA 2BXPA 2XW0A 3V09A 5IJEA 1AO6A 4F5TA 1HK5A 5DBYA 4ZBRA 2BXAA 4LB2A 2VUEA 4IW1A 3B9LA 3V08A
chains in the Genus database with same CATH superfamily
4GG2A 1E7CA 1E7FA 1LOTA 3JQZA 4OTTA 4DHXB 3G9KD 2YDFA 3NMUA 3WHSA 4IW2A 2QHBA 2BXIA 2LXTA 4TQ1A 5IIHA 3B9MA 1JNBA 1UORA 5DQFA 4FK5B 4LUFA 3CX9A 5GIOA 2EFCA 2BXCA 4N0UD 4S1YA 1E7EA 2OZBB 3GQXA 4J2VA 4LA0A 4N3ZA 1H9ZA 2BXQA 1E7AA 2XMOA 4F5VA 3SIVB 3SIUB 1GNIA 3UIVA 2V36A 2I2ZA 2OT3A 1HK2A 2LQIA 5D7GA 2XVVA 2BXMA 1E78A 4DM0A 4JK4A 2BXFA 2XVQA 1SB0A 3GA9L 2BXBA 3KJLA 4GDLB 2KBZA 2XW1A 4ZUXV 2K0NA 5IJFA 4FIPB 2BXOA 4ZBQA 2GUTA 2XVUA 3LU8A 2LXSA 4BKEA 5GINA 1IJGA 1KXPD 4LB9A 3NVIA 3WHQA 4L9QA 2QM6A 2DG5A 1MIVA 5IIUA 3LU6A 4G03A 4EMXA 1MA9A 2AGHB 1MUHA 5IIXA 1E7IA 4TQ0A 4F5UA 4L8UA 2EFHA 4ZCGA 2BXDA 5BPKA 4ZC6A 3H37A 3V03A 1VFIA 2VDBA 4HGKA 5ID7A 1TXUA 2XSIA 1LNSA 5HOZA 1N5UA 2BXGA 1HK1A 3A73A 4GDKB 1E7GA 4OT2A 2EFDA 2DYOA 1FOUA 1KW2A 1MM8A 4PO0A 1BKEA 4L9KA 4LUHA 2DBXA 4K71A 3PLAA 2Z8JA 4N0FD 2CKXA 2I30A 2BXHA 4ZBKA 4OR0A 2BXNA 2BXKA 1MUSA 3MHSB 3NVMA 4K2CA 4D7XA 2BXLA 2BXEA 4FJCB 1BJ5A 3GQUA 5FUOA 2BX8A 5IJ5A 3LU7A 2ROHA 3ICXA 3H3AA 4Z69A 4OTUA 1MIWA 2Z8IA 4C31B 3WHRA 3A75A 4M70B 3ECPA 1HK4A 2NQOA 2VUFA 3FWCC 4MBEC 1HA2A 4HGMB 3VQIA 4G01A 2EFEA 1VZSA 3M99C 3NVKA 2LQHA 3KIKA 2E0YA 1TF0A 3JRYA 5IFOA 3W1SA 2NNWA 2DBUA 3BPJA 2JUHA 1BM0A 2AJEA 4F5SA 1HK3A 5B5TA 4G04A 1O9XA 5GHKA 3SQJA 4E99A 1GNJA 2QMCA 5ID9A 3TDLA 2XVWA 1J78A 2DYMA 3FWBC 1E7BA 1E7HA 4Z9OA 1J7EA 4NAWB 2BXPA 2XW0A 3V09A 5IJEA 1AO6A 1KDXA 4I9OA 4BY9C 4F5TA 5GIPA 2E0XA 1H5WA 1HK5A 5DBYA 4WA6B 3MHHB 4ZBRA 2BXAA 2DBWA 4GDXA 4W4UB 1MIYA 2KWFA 4LB2A 2VUEA 4IW1A 3B9LA 3V08A 2Z8KA 3FNMA 1NT2B 2LOQA
chains in the Genus database with same CATH topology
4GG2A 1E7CA 1E7FA 1LOTA 3JQZA 4OTTA 4DHXB 3G9KD 2YDFA 3NMUA 3WHSA 4IW2A 2QHBA 2BXIA 4TQ1A 5IIHA 3B9MA 1JNBA 1UORA 5DQFA 4FK5B 4LUFA 3CX9A 5GIOA 2EFCA 2BXCA 4N0UD 4S1YA 1E7EA 2OZBB 3GQXA 4J2VA 4LA0A 4N3ZA 1H9ZA 2BXQA 1E7AA 2XMOA 4F5VA 3SIVB 3SIUB 1GNIA 3UIVA 2V36A 2I2ZA 2OT3A 1HK2A 5D7GA 2XVVA 2BXMA 1E78A 4JK4A 2BXFA 2XVQA 3KJLA 3GA9L 2BXBA 4GDLB 2KBZA 2XW1A 4ZUXV 5IJFA 4FIPB 2BXOA 4ZBQA 2XVUA 3LU8A 4BKEA 5GINA 1IJGA 1KXPD 4LB9A 3NVIA 3WHQA 4L9QA 2QM6A 2DG5A 1MIVA 5IIUA 3LU6A 4G03A 4EMXA 1MA9A 5IIXA 1E7IA 4TQ0A 4F5UA 4L8UA 2EFHA 4ZCGA 2BXDA 5BPKA 4ZC6A 3H37A 3V03A 1VFIA 2VDBA 4HGKA 5ID7A 1TXUA 2XSIA 1LNSA 5HOZA 1N5UA 2BXGA 1HK1A 3A73A 4GDKB 1E7GA 4OT2A 2EFDA 2DYOA 1FOUA 1KW2A 4PO0A 1BKEA 4L9KA 4LUHA 2DBXA 4K71A 3PLAA 2Z8JA 4N0FD 2CKXA 2I30A 2BXHA 4ZBKA 4OR0A 2BXNA 2BXKA 3MHSB 3NVMA 4K2CA 2BXLA 2BXEA 4FJCB 1BJ5A 3GQUA 5FUOA 2BX8A 5IJ5A 3LU7A 2ROHA 3ICXA 3H3AA 4Z69A 4OTUA 1MIWA 2Z8IA 4C31B 3WHRA 3A75A 4M70B 1HK4A 2NQOA 2VUFA 3FWCC 4MBEC 1HA2A 4HGMB 3VQIA 4G01A 2EFEA 1VZSA 3M99C 3NVKA 3KIKA 2E0YA 1TF0A 3JRYA 5IFOA 3W1SA 2NNWA 2DBUA 2JUHA 1BM0A 2AJEA 4F5SA 1HK3A 5B5TA 4G04A 1O9XA 5GHKA 3SQJA 4E99A 1GNJA 2QMCA 5ID9A 3TDLA 2XVWA 1J78A 2DYMA 3FWBC 1E7BA 1E7HA 4Z9OA 1J7EA 4NAWB 2BXPA 2XW0A 3V09A 5IJEA 1AO6A 4BY9C 4F5TA 5GIPA 2E0XA 1H5WA 1HK5A 5DBYA 4WA6B 3MHHB 4ZBRA 2BXAA 2DBWA 4GDXA 4W4UB 1MIYA 4LB2A 2VUEA 4IW1A 3B9LA 3V08A 2Z8KA 3FNMA 1NT2B 2LOQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E7C A;  1E7F A;  1LOT A;  3JQZ A;  2YDF A;  4IW2 A;  2BXI A;  5IIH A;  3B9M A;  1UOR A;  5DQF A;  4LUF A;  3CX9 A;  2BXC A;  4N0U D;  4S1Y A;  1E7E A;  4J2V A;  4LA0 A;  1H9Z A;  2BXQ A;  1E7A A;  4F5V A;  1GNI A;  3UIV A;  2I2Z A;  1HK2 A;  2XVV A;  2BXM A;  1E78 A;  4JK4 A;  2BXF A;  2XVQ A;  2BXB A;  2XW1 A;  5IJF A;  2BXO A;  4ZBQ A;  2XVU A;  3LU8 A;  4BKE A;  1KXP D;  4LB9 A;  4L9Q A;  5IIU A;  3LU6 A;  4G03 A;  4EMX A;  1MA9 A;  5IIX A;  1E7I A;  4F5U A;  4L8U A;  2BXD A;  5ID7 A;  3V03 A;  2VDB A;  4HGK A;  2XSI A;  5HOZ A;  1N5U A;  2BXG A;  1HK1 A;  3A73 A;  1E7G A;  4OT2 A;  1KW2 A;  4PO0 A;  1BKE A;  4L9K A;  4LUH A;  4K71 A;  4N0F D;  2I30 A;  2BXH A;  4OR0 A;  2BXN A;  2BXK A;  4K2C A;  2BXL A;  2BXE A;  1BJ5 A;  5FUO A;  2BX8 A;  5IJ5 A;  3LU7 A;  4Z69 A;  1HK4 A;  2VUF A;  1HA2 A;  4HGM B;  1TF0 A;  3JRY A;  5IFO A;  1BM0 A;  4F5S A;  1HK3 A;  4G04 A;  1O9X A;  5GHK A;  3SQJ A;  4E99 A;  1GNJ A;  5ID9 A;  3TDL A;  2XVW A;  1J78 A;  1E7B A;  1E7H A;  1J7E A;  2BXP A;  2XW0 A;  3V09 A;  5IJE A;  1AO6 A;  4F5T A;  1HK5 A;  5DBY A;  4ZBR A;  2BXA A;  4LB2 A;  2VUE A;  4IW1 A;  3B9L A;  3V08 A; 
#chains in the Genus database with same CATH topology
 4GG2 A;  1E7C A;  1E7F A;  1LOT A;  3JQZ A;  4OTT A;  4DHX B;  3G9K D;  2YDF A;  3NMU A;  3WHS A;  4IW2 A;  2QHB A;  2BXI A;  2LXT A;  4TQ1 A;  5IIH A;  3B9M A;  1JNB A;  1UOR A;  5DQF A;  4FK5 B;  4LUF A;  3CX9 A;  5GIO A;  2EFC A;  2BXC A;  4N0U D;  4S1Y A;  1E7E A;  2OZB B;  3GQX A;  4J2V A;  4LA0 A;  4N3Z A;  1H9Z A;  2BXQ A;  1E7A A;  2XMO A;  4F5V A;  3SIV B;  3SIU B;  1GNI A;  3UIV A;  2V36 A;  2I2Z A;  2OT3 A;  1HK2 A;  2LQI A;  5D7G A;  2XVV A;  2BXM A;  1E78 A;  4DM0 A;  4JK4 A;  2BXF A;  2XVQ A;  1SB0 A;  3GA9 L;  2BXB A;  3KJL A;  4GDL B;  2KBZ A;  2XW1 A;  4ZUX V;  2K0N A;  5IJF A;  4FIP B;  2BXO A;  4ZBQ A;  2GUT A;  2XVU A;  3LU8 A;  2LXS A;  4BKE A;  5GIN A;  1IJG A;  1KXP D;  4LB9 A;  3NVI A;  3WHQ A;  4L9Q A;  2QM6 A;  2DG5 A;  1MIV A;  5IIU A;  3LU6 A;  4G03 A;  4EMX A;  1MA9 A;  2AGH B;  1MUH A;  5IIX A;  1E7I A;  4TQ0 A;  4F5U A;  4L8U A;  2EFH A;  4ZCG A;  2BXD A;  5BPK A;  4ZC6 A;  3H37 A;  3V03 A;  1VFI A;  2VDB A;  4HGK A;  5ID7 A;  1TXU A;  2XSI A;  1LNS A;  5HOZ A;  1N5U A;  2BXG A;  1HK1 A;  3A73 A;  4GDK B;  1E7G A;  4OT2 A;  2EFD A;  2DYO A;  1FOU A;  1KW2 A;  1MM8 A;  4PO0 A;  1BKE A;  4L9K A;  4LUH A;  2DBX A;  4K71 A;  3PLA A;  2Z8J A;  4N0F D;  2CKX A;  2I30 A;  2BXH A;  4ZBK A;  4OR0 A;  2BXN A;  2BXK A;  1MUS A;  3MHS B;  3NVM A;  4K2C A;  4D7X A;  2BXL A;  2BXE A;  4FJC B;  1BJ5 A;  3GQU A;  5FUO A;  2BX8 A;  5IJ5 A;  3LU7 A;  2ROH A;  3ICX A;  3H3A A;  4Z69 A;  4OTU A;  1MIW A;  2Z8I A;  4C31 B;  3WHR A;  3A75 A;  4M70 B;  3ECP A;  1HK4 A;  2NQO A;  2VUF A;  3FWC C;  4MBE C;  1HA2 A;  4HGM B;  3VQI A;  4G01 A;  2EFE A;  1VZS A;  3M99 C;  3NVK A;  2LQH A;  3KIK A;  2E0Y A;  1TF0 A;  3JRY A;  5IFO A;  3W1S A;  2NNW A;  2DBU A;  3BPJ A;  2JUH A;  1BM0 A;  2AJE A;  4F5S A;  1HK3 A;  5B5T A;  4G04 A;  1O9X A;  5GHK A;  3SQJ A;  4E99 A;  1GNJ A;  2QMC A;  5ID9 A;  3TDL A;  2XVW A;  1J78 A;  2DYM A;  3FWB C;  1E7B A;  1E7H A;  4Z9O A;  1J7E A;  4NAW B;  2BXP A;  2XW0 A;  3V09 A;  5IJE A;  1AO6 A;  1KDX A;  4I9O A;  4BY9 C;  4F5T A;  5GIP A;  2E0X A;  1H5W A;  1HK5 A;  5DBY A;  4WA6 B;  3MHH B;  4ZBR A;  2BXA A;  2DBW A;  4GDX A;  4W4U B;  1MIY A;  2KWF A;  4LB2 A;  2VUE A;  4IW1 A;  3B9L A;  3V08 A;  2Z8K A;  3FNM A;  1NT2 B;  2LOQ A; 
#chains in the Genus database with same CATH homology
 4GG2 A;  1E7C A;  1E7F A;  1LOT A;  3JQZ A;  4OTT A;  4DHX B;  3G9K D;  2YDF A;  3NMU A;  3WHS A;  4IW2 A;  2QHB A;  2BXI A;  4TQ1 A;  5IIH A;  3B9M A;  1JNB A;  1UOR A;  5DQF A;  4FK5 B;  4LUF A;  3CX9 A;  5GIO A;  2EFC A;  2BXC A;  4N0U D;  4S1Y A;  1E7E A;  2OZB B;  3GQX A;  4J2V A;  4LA0 A;  4N3Z A;  1H9Z A;  2BXQ A;  1E7A A;  2XMO A;  4F5V A;  3SIV B;  3SIU B;  1GNI A;  3UIV A;  2V36 A;  2I2Z A;  2OT3 A;  1HK2 A;  5D7G A;  2XVV A;  2BXM A;  1E78 A;  4JK4 A;  2BXF A;  2XVQ A;  3KJL A;  3GA9 L;  2BXB A;  4GDL B;  2KBZ A;  2XW1 A;  4ZUX V;  5IJF A;  4FIP B;  2BXO A;  4ZBQ A;  2XVU A;  3LU8 A;  4BKE A;  5GIN A;  1IJG A;  1KXP D;  4LB9 A;  3NVI A;  3WHQ A;  4L9Q A;  2QM6 A;  2DG5 A;  1MIV A;  5IIU A;  3LU6 A;  4G03 A;  4EMX A;  1MA9 A;  5IIX A;  1E7I A;  4TQ0 A;  4F5U A;  4L8U A;  2EFH A;  4ZCG A;  2BXD A;  5BPK A;  4ZC6 A;  3H37 A;  3V03 A;  1VFI A;  2VDB A;  4HGK A;  5ID7 A;  1TXU A;  2XSI A;  1LNS A;  5HOZ A;  1N5U A;  2BXG A;  1HK1 A;  3A73 A;  4GDK B;  1E7G A;  4OT2 A;  2EFD A;  2DYO A;  1FOU A;  1KW2 A;  4PO0 A;  1BKE A;  4L9K A;  4LUH A;  2DBX A;  4K71 A;  3PLA A;  2Z8J A;  4N0F D;  2CKX A;  2I30 A;  2BXH A;  4ZBK A;  4OR0 A;  2BXN A;  2BXK A;  3MHS B;  3NVM A;  4K2C A;  2BXL A;  2BXE A;  4FJC B;  1BJ5 A;  3GQU A;  5FUO A;  2BX8 A;  5IJ5 A;  3LU7 A;  2ROH A;  3ICX A;  3H3A A;  4Z69 A;  4OTU A;  1MIW A;  2Z8I A;  4C31 B;  3WHR A;  3A75 A;  4M70 B;  1HK4 A;  2NQO A;  2VUF A;  3FWC C;  4MBE C;  1HA2 A;  4HGM B;  3VQI A;  4G01 A;  2EFE A;  1VZS A;  3M99 C;  3NVK A;  3KIK A;  2E0Y A;  1TF0 A;  3JRY A;  5IFO A;  3W1S A;  2NNW A;  2DBU A;  2JUH A;  1BM0 A;  2AJE A;  4F5S A;  1HK3 A;  5B5T A;  4G04 A;  1O9X A;  5GHK A;  3SQJ A;  4E99 A;  1GNJ A;  2QMC A;  5ID9 A;  3TDL A;  2XVW A;  1J78 A;  2DYM A;  3FWB C;  1E7B A;  1E7H A;  4Z9O A;  1J7E A;  4NAW B;  2BXP A;  2XW0 A;  3V09 A;  5IJE A;  1AO6 A;  4BY9 C;  4F5T A;  5GIP A;  2E0X A;  1H5W A;  1HK5 A;  5DBY A;  4WA6 B;  3MHH B;  4ZBR A;  2BXA A;  2DBW A;  4GDX A;  4W4U B;  1MIY A;  4LB2 A;  2VUE A;  4IW1 A;  3B9L A;  3V08 A;  2Z8K A;  3FNM A;  1NT2 B;  2LOQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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