4HGMB

Shark ignar variable domain
Total Genus 173
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
sequence length
489
structure length
478
Chain Sequence
KSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVAEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCSLVNRRPCFSALE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis.
pubmed doi rcsb
molecule keywords Shark V-NAR
molecule tags Immune system
source organism Squalus acanthias
total genus 173
structure length 478
sequence length 489
ec nomenclature
pdb deposition date 2012-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4hgmB02
1KW2A 5IJ5A 4IW1A 1LOTA 4Z69A 5IJEA 4G04A 3SQJA 1E7FA 1BKEA 2BXNA 4HGKA 4OT2A 2BXKA 4J2VA 4LB2A 1GNJA 2XW0A 1GNIA 5IJFA 3CX9A 3V03A 3LU6A 2BXOA 5HOZA 1KXPD 2YDFA 4IW2A 2BXQA 1N5UA 5DBYA 4LUFA 4L9KA 5DQFA 2BXGA 3TDLA 4F5TA 4K2CA 2VUFA 1E7IA 3B9LA 1O9XA 5IFOA 1E7EA 4EMXA 4PO0A 1HK3A 3LU8A 5GHKA 2BXMA 3JRYA 5IIXA 4F5UA 1AO6A 2BXHA 4BKEA 1J78A 4N0FD 2BXPA 3UIVA 2BXLA 1E78A 2XVQA 3A73A 4OR0A 2XVWA 1HA2A 5IIUA 2BXBA 4S1YA 1BM0A 1TF0A 2BXEA 4LB9A 3V09A 1UORA 1E7HA 2BX8A 4JK4A 1HK1A 1HK2A 4G03A 2BXIA 4LA0A 2I30A 1HK5A 2BXAA 4L8UA 1E7BA 4ZBRA 1E7AA 4L9QA 1H9ZA 4LUHA 2BXDA 4HGMB 2VUEA 2XVVA 1E7GA 1HK4A 2BXCA 1BJ5A 3V08A 5ID9A 4E99A 4F5SA 3B9MA 2XSIA 2I2ZA 2XW1A 1MA9A 2BXFA 4N0UD 1J7EA 4F5VA 1E7CA 5ID7A 5FUOA 4ZBQA 3LU7A 2XVUA 4K71A 3JQZA 5IIHA 2VDBA
chains in the Genus database with same CATH superfamily
3MHHB 2NQOA 3ICXA 1KW2A 5IJ5A 4IW1A 1LOTA 2DBWA 2LOQA 4Z69A 5IJEA 4G04A 3H37A 3SQJA 1E7FA 1BKEA 2QM6A 4ZBKA 5IIHA 4GG2A 4DHXB 2BXNA 2QMCA 3WHRA 3G9KD 4HGKA 4G01A 4OT2A 2BXKA 4J2VA 3WHSA 4LB2A 1GNJA 5GINA 5BPKA 2XW0A 1GNIA 5GIPA 5IJFA 3CX9A 3V03A 2AGHB 3LU6A 2Z8JA 3H3AA 4FK5B 4GDKB 2JUHA 3ECPA 2CKXA 4C31B 2BXOA 2EFCA 3KJLA 4I9OA 5HOZA 1KXPD 2E0YA 2YDFA 3FWCC 4IW2A 2BXQA 4OTUA 1N5UA 5DBYA 3W1SA 2EFEA 1MUSA 4LUFA 3WHQA 4L9KA 5DQFA 4TQ1A 2K0NA 4D7XA 2BXGA 3TDLA 4ZUXV 3SIUB 4F5TA 1JNBA 4K2CA 2AJEA 3M99C 3NVIA 2VUFA 1E7IA 3FWBC 3B9LA 4N3ZA 1O9XA 2LQHA 4DM0A 5IFOA 1MIVA 2GUTA 4WA6B 2E0XA 4GDLB 4MBEC 2QHBA 2Z8KA 4OTTA 1LNSA 1IJGA 3MHSB 5GIOA 1E7EA 4ZC6A 3VQIA 4EMXA 2OT3A 2DG5A 2DYOA 4PO0A 2OZBB 1HK3A 2NNWA 4BY9C 3LU8A 5GHKA 2BXMA 2DBXA 3JRYA 2KWFA 5IIXA 3FNMA 4F5UA 1AO6A 1VZSA 2BXHA 4BKEA 1J78A 1H5WA 4ZCGA 4N0FD 2EFDA 2BXPA 2KBZA 2BXLA 1E78A 2XVQA 3A73A 4OR0A 3UIVA 2XVWA 4TQ0A 3SIVB 4GDXA 3BPJA 1FOUA 2LXTA 1HA2A 5IIUA 1MIWA 2BXBA 2Z8IA 3GQUA 4S1YA 1BM0A 1VFIA 1TF0A 2BXEA 4LB9A 5B5TA 3V09A 1UORA 2DYMA 2ROHA 5D7GA 1KDXA 1E7HA 2BX8A 4JK4A 4M70B 1HK1A 3NMUA 1HK2A 3GQXA 2BXIA 4G03A 2I30A 4LA0A 1HK5A 2BXAA 4FIPB 1E7BA 4L8UA 1MIYA 4ZBRA 1E7AA 4L9QA 1H9ZA 4FJCB 2V36A 4LUHA 1NT2B 2BXDA 2EFHA 2LQIA 4HGMB 1TXUA 2VUEA 2XVVA 1E7GA 1HK4A 2LXSA 2BXCA 1BJ5A 3V08A 3PLAA 5ID9A 4E99A 4F5SA 3KIKA 4Z9OA 3B9MA 1MM8A 3NVMA 2XSIA 2I2ZA 2XW1A 1MA9A 2BXFA 4N0UD 1J7EA 3A75A 1MUHA 4W4UB 4F5VA 1E7CA 5ID7A 3NVKA 5FUOA 4ZBQA 3LU7A 2XMOA 2XVUA 4K71A 1SB0A 4NAWB 3GA9L 3JQZA 2DBUA 2VDBA
chains in the Genus database with same CATH topology
3MHHB 2NQOA 3ICXA 1KW2A 5IJ5A 4IW1A 1LOTA 2DBWA 2LOQA 4Z69A 5IJEA 4G04A 3H37A 3SQJA 1E7FA 1BKEA 2QM6A 4ZBKA 5IIHA 4GG2A 4DHXB 2BXNA 2QMCA 3WHRA 3G9KD 4HGKA 4G01A 4OT2A 2BXKA 4J2VA 3WHSA 4LB2A 1GNJA 5GINA 5BPKA 2XW0A 1GNIA 5GIPA 5IJFA 3CX9A 3V03A 3LU6A 2Z8JA 3H3AA 4FK5B 4GDKB 2JUHA 2CKXA 4C31B 2BXOA 2EFCA 3KJLA 5HOZA 1KXPD 2E0YA 2YDFA 3FWCC 4IW2A 2BXQA 4OTUA 1N5UA 5DBYA 3W1SA 2EFEA 4LUFA 3WHQA 4L9KA 5DQFA 4TQ1A 2BXGA 3TDLA 4ZUXV 3SIUB 4F5TA 1JNBA 4K2CA 2AJEA 3M99C 3NVIA 2VUFA 1E7IA 3FWBC 3B9LA 4N3ZA 1O9XA 5IFOA 1MIVA 4WA6B 2E0XA 4GDLB 4MBEC 2QHBA 2Z8KA 4OTTA 1LNSA 1IJGA 3MHSB 5GIOA 1E7EA 4ZC6A 3VQIA 4EMXA 2OT3A 2DG5A 2DYOA 4PO0A 2OZBB 1HK3A 2NNWA 4BY9C 3LU8A 5GHKA 2BXMA 2DBXA 3JRYA 5IIXA 3FNMA 4F5UA 1AO6A 1VZSA 2BXHA 4BKEA 1J78A 1H5WA 4ZCGA 4N0FD 2EFDA 2BXPA 2KBZA 2BXLA 1E78A 2XVQA 3A73A 4OR0A 3UIVA 2XVWA 4TQ0A 3SIVB 4GDXA 1FOUA 1HA2A 5IIUA 1MIWA 2BXBA 2Z8IA 3GQUA 4S1YA 1BM0A 1VFIA 1TF0A 2BXEA 4LB9A 5B5TA 3V09A 1UORA 2DYMA 2ROHA 5D7GA 1E7HA 2BX8A 4JK4A 4M70B 1HK1A 3NMUA 1HK2A 3GQXA 2BXIA 4G03A 2I30A 4LA0A 1HK5A 2BXAA 4FIPB 1E7BA 4L8UA 1MIYA 4ZBRA 1E7AA 4L9QA 1H9ZA 4FJCB 2V36A 4LUHA 1NT2B 2BXDA 2EFHA 4HGMB 1TXUA 2VUEA 2XVVA 1E7GA 1HK4A 2BXCA 1BJ5A 3V08A 3PLAA 5ID9A 4E99A 4F5SA 3KIKA 4Z9OA 3B9MA 3NVMA 2XSIA 2I2ZA 2XW1A 1MA9A 2BXFA 4N0UD 1J7EA 3A75A 4W4UB 4F5VA 1E7CA 5ID7A 3NVKA 5FUOA 4ZBQA 3LU7A 2XMOA 2XVUA 4K71A 4NAWB 3GA9L 3JQZA 2DBUA 2VDBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KW2 A;  5IJ5 A;  4IW1 A;  1LOT A;  4Z69 A;  5IJE A;  4G04 A;  3SQJ A;  1E7F A;  1BKE A;  2BXN A;  4HGK A;  4OT2 A;  2BXK A;  4J2V A;  4LB2 A;  1GNJ A;  2XW0 A;  1GNI A;  5IJF A;  3CX9 A;  3V03 A;  3LU6 A;  2BXO A;  5HOZ A;  1KXP D;  2YDF A;  4IW2 A;  2BXQ A;  1N5U A;  5DBY A;  4LUF A;  4L9K A;  5DQF A;  2BXG A;  3TDL A;  4F5T A;  4K2C A;  2VUF A;  1E7I A;  3B9L A;  1O9X A;  5IFO A;  1E7E A;  4EMX A;  4PO0 A;  1HK3 A;  3LU8 A;  5GHK A;  2BXM A;  3JRY A;  5IIX A;  4F5U A;  1AO6 A;  2BXH A;  4BKE A;  1J78 A;  4N0F D;  2BXP A;  3UIV A;  2BXL A;  1E78 A;  2XVQ A;  3A73 A;  4OR0 A;  2XVW A;  1HA2 A;  5IIU A;  2BXB A;  4S1Y A;  1BM0 A;  1TF0 A;  2BXE A;  4LB9 A;  3V09 A;  1UOR A;  1E7H A;  2BX8 A;  4JK4 A;  1HK1 A;  1HK2 A;  4G03 A;  2BXI A;  4LA0 A;  2I30 A;  1HK5 A;  2BXA A;  4L8U A;  1E7B A;  4ZBR A;  1E7A A;  4L9Q A;  1H9Z A;  4LUH A;  2BXD A;  4HGM B;  2VUE A;  2XVV A;  1E7G A;  1HK4 A;  2BXC A;  1BJ5 A;  3V08 A;  5ID9 A;  4E99 A;  4F5S A;  3B9M A;  2XSI A;  2I2Z A;  2XW1 A;  1MA9 A;  2BXF A;  4N0U D;  1J7E A;  4F5V A;  1E7C A;  5ID7 A;  5FUO A;  4ZBQ A;  3LU7 A;  2XVU A;  4K71 A;  3JQZ A;  5IIH A;  2VDB A; 
#chains in the Genus database with same CATH topology
 3MHH B;  2NQO A;  3ICX A;  1KW2 A;  5IJ5 A;  4IW1 A;  1LOT A;  2DBW A;  2LOQ A;  4Z69 A;  5IJE A;  4G04 A;  3H37 A;  3SQJ A;  1E7F A;  1BKE A;  2QM6 A;  4ZBK A;  5IIH A;  4GG2 A;  4DHX B;  2BXN A;  2QMC A;  3WHR A;  3G9K D;  4HGK A;  4G01 A;  4OT2 A;  2BXK A;  4J2V A;  3WHS A;  4LB2 A;  1GNJ A;  5GIN A;  5BPK A;  2XW0 A;  1GNI A;  5GIP A;  5IJF A;  3CX9 A;  3V03 A;  2AGH B;  3LU6 A;  2Z8J A;  3H3A A;  4FK5 B;  4GDK B;  2JUH A;  3ECP A;  2CKX A;  4C31 B;  2BXO A;  2EFC A;  3KJL A;  4I9O A;  5HOZ A;  1KXP D;  2E0Y A;  2YDF A;  3FWC C;  4IW2 A;  2BXQ A;  4OTU A;  1N5U A;  5DBY A;  3W1S A;  2EFE A;  1MUS A;  4LUF A;  3WHQ A;  4L9K A;  5DQF A;  4TQ1 A;  2K0N A;  4D7X A;  2BXG A;  3TDL A;  4ZUX V;  3SIU B;  4F5T A;  1JNB A;  4K2C A;  2AJE A;  3M99 C;  3NVI A;  2VUF A;  1E7I A;  3FWB C;  3B9L A;  4N3Z A;  1O9X A;  2LQH A;  4DM0 A;  5IFO A;  1MIV A;  2GUT A;  4WA6 B;  2E0X A;  4GDL B;  4MBE C;  2QHB A;  2Z8K A;  4OTT A;  1LNS A;  1IJG A;  3MHS B;  5GIO A;  1E7E A;  4ZC6 A;  3VQI A;  4EMX A;  2OT3 A;  2DG5 A;  2DYO A;  4PO0 A;  2OZB B;  1HK3 A;  2NNW A;  4BY9 C;  3LU8 A;  5GHK A;  2BXM A;  2DBX A;  3JRY A;  2KWF A;  5IIX A;  3FNM A;  4F5U A;  1AO6 A;  1VZS A;  2BXH A;  4BKE A;  1J78 A;  1H5W A;  4ZCG A;  4N0F D;  2EFD A;  2BXP A;  2KBZ A;  2BXL A;  1E78 A;  2XVQ A;  3A73 A;  4OR0 A;  3UIV A;  2XVW A;  4TQ0 A;  3SIV B;  4GDX A;  3BPJ A;  1FOU A;  2LXT A;  1HA2 A;  5IIU A;  1MIW A;  2BXB A;  2Z8I A;  3GQU A;  4S1Y A;  1BM0 A;  1VFI A;  1TF0 A;  2BXE A;  4LB9 A;  5B5T A;  3V09 A;  1UOR A;  2DYM A;  2ROH A;  5D7G A;  1KDX A;  1E7H A;  2BX8 A;  4JK4 A;  4M70 B;  1HK1 A;  3NMU A;  1HK2 A;  3GQX A;  2BXI A;  4G03 A;  2I30 A;  4LA0 A;  1HK5 A;  2BXA A;  4FIP B;  1E7B A;  4L8U A;  1MIY A;  4ZBR A;  1E7A A;  4L9Q A;  1H9Z A;  4FJC B;  2V36 A;  4LUH A;  1NT2 B;  2BXD A;  2EFH A;  2LQI A;  4HGM B;  1TXU A;  2VUE A;  2XVV A;  1E7G A;  1HK4 A;  2LXS A;  2BXC A;  1BJ5 A;  3V08 A;  3PLA A;  5ID9 A;  4E99 A;  4F5S A;  3KIK A;  4Z9O A;  3B9M A;  1MM8 A;  3NVM A;  2XSI A;  2I2Z A;  2XW1 A;  1MA9 A;  2BXF A;  4N0U D;  1J7E A;  3A75 A;  1MUH A;  4W4U B;  4F5V A;  1E7C A;  5ID7 A;  3NVK A;  5FUO A;  4ZBQ A;  3LU7 A;  2XMO A;  2XVU A;  4K71 A;  1SB0 A;  4NAW B;  3GA9 L;  3JQZ A;  2DBU A;  2VDB A; 
#chains in the Genus database with same CATH homology
 3MHH B;  2NQO A;  3ICX A;  1KW2 A;  5IJ5 A;  4IW1 A;  1LOT A;  2DBW A;  2LOQ A;  4Z69 A;  5IJE A;  4G04 A;  3H37 A;  3SQJ A;  1E7F A;  1BKE A;  2QM6 A;  4ZBK A;  5IIH A;  4GG2 A;  4DHX B;  2BXN A;  2QMC A;  3WHR A;  3G9K D;  4HGK A;  4G01 A;  4OT2 A;  2BXK A;  4J2V A;  3WHS A;  4LB2 A;  1GNJ A;  5GIN A;  5BPK A;  2XW0 A;  1GNI A;  5GIP A;  5IJF A;  3CX9 A;  3V03 A;  3LU6 A;  2Z8J A;  3H3A A;  4FK5 B;  4GDK B;  2JUH A;  2CKX A;  4C31 B;  2BXO A;  2EFC A;  3KJL A;  5HOZ A;  1KXP D;  2E0Y A;  2YDF A;  3FWC C;  4IW2 A;  2BXQ A;  4OTU A;  1N5U A;  5DBY A;  3W1S A;  2EFE A;  4LUF A;  3WHQ A;  4L9K A;  5DQF A;  4TQ1 A;  2BXG A;  3TDL A;  4ZUX V;  3SIU B;  4F5T A;  1JNB A;  4K2C A;  2AJE A;  3M99 C;  3NVI A;  2VUF A;  1E7I A;  3FWB C;  3B9L A;  4N3Z A;  1O9X A;  5IFO A;  1MIV A;  4WA6 B;  2E0X A;  4GDL B;  4MBE C;  2QHB A;  2Z8K A;  4OTT A;  1LNS A;  1IJG A;  3MHS B;  5GIO A;  1E7E A;  4ZC6 A;  3VQI A;  4EMX A;  2OT3 A;  2DG5 A;  2DYO A;  4PO0 A;  2OZB B;  1HK3 A;  2NNW A;  4BY9 C;  3LU8 A;  5GHK A;  2BXM A;  2DBX A;  3JRY A;  5IIX A;  3FNM A;  4F5U A;  1AO6 A;  1VZS A;  2BXH A;  4BKE A;  1J78 A;  1H5W A;  4ZCG A;  4N0F D;  2EFD A;  2BXP A;  2KBZ A;  2BXL A;  1E78 A;  2XVQ A;  3A73 A;  4OR0 A;  3UIV A;  2XVW A;  4TQ0 A;  3SIV B;  4GDX A;  1FOU A;  1HA2 A;  5IIU A;  1MIW A;  2BXB A;  2Z8I A;  3GQU A;  4S1Y A;  1BM0 A;  1VFI A;  1TF0 A;  2BXE A;  4LB9 A;  5B5T A;  3V09 A;  1UOR A;  2DYM A;  2ROH A;  5D7G A;  1E7H A;  2BX8 A;  4JK4 A;  4M70 B;  1HK1 A;  3NMU A;  1HK2 A;  3GQX A;  2BXI A;  4G03 A;  2I30 A;  4LA0 A;  1HK5 A;  2BXA A;  4FIP B;  1E7B A;  4L8U A;  1MIY A;  4ZBR A;  1E7A A;  4L9Q A;  1H9Z A;  4FJC B;  2V36 A;  4LUH A;  1NT2 B;  2BXD A;  2EFH A;  4HGM B;  1TXU A;  2VUE A;  2XVV A;  1E7G A;  1HK4 A;  2BXC A;  1BJ5 A;  3V08 A;  3PLA A;  5ID9 A;  4E99 A;  4F5S A;  3KIK A;  4Z9O A;  3B9M A;  3NVM A;  2XSI A;  2I2Z A;  2XW1 A;  1MA9 A;  2BXF A;  4N0U D;  1J7E A;  3A75 A;  4W4U B;  4F5V A;  1E7C A;  5ID7 A;  3NVK A;  5FUO A;  4ZBQ A;  3LU7 A;  2XMO A;  2XVU A;  4K71 A;  4NAW B;  3GA9 L;  3JQZ A;  2DBU A;  2VDB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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