4IW2A

Hsa-glucose complex
Total Genus 218
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural mechanism of ring-opening reaction of glucose by human serum albumin
pubmed doi rcsb
molecule keywords Serum albumin
molecule tags Transport protein
source organism Homo sapiens
total genus 218
structure length 578
sequence length 578
ec nomenclature
pdb deposition date 2013-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4iw2A05
2BXFA 2XVVA 5DQFA 1E7GA 4OR0A 4HGKA 3B9LA 4BKEA 5DBYA 4F5SA 1E7FA 5ID7A 2BXCA 1N5UA 1J78A 1GNJA 1KXPD 4G03A 4L9QA 4L8UA 4Z69A 4EMXA 3B9MA 2BXEA 1GNIA 4K2CA 2BXDA 4G04A 2BXOA 2BXQA 1E7AA 2YDFA 3A73A 1E7BA 1HK3A 2BXMA 2BX8A 1HK1A 2XVQA 5IIHA 5GHKA 4IW2A 1HA2A 4LUFA 2XVWA 3JQZA 2BXBA 1E78A 4JK4A 2BXIA 3V09A 1J7EA 2BXGA 3CX9A 4K71A 4S1YA 4IW1A 2BXLA 4F5UA 2BXKA 5IJEA 5IIXA 4L9KA 2BXPA 2I2ZA 2XW0A 1LOTA 1BKEA 5ID9A 2VUEA 4LUHA 5FUOA 1KW2A 3LU7A 4OT2A 4F5TA 5IIUA 4N0UD 5HOZA 2VUFA 4N0FD 3UIVA 1O9XA 4PO0A 1AO6A 5IJFA 2VDBA 1H9ZA 3LU8A 3SQJA 1E7HA 1E7EA 3LU6A 3V03A 4E99A 4HGMB 1E7CA 4ZBQA 1BJ5A 1UORA 2XW1A 4J2VA 1HK4A 1HK5A 1MA9A 4LB2A 5IFOA 3V08A 1BM0A 4LA0A 3JRYA 1HK2A 4F5VA 2BXAA 2BXNA 5IJ5A 4LB9A 2BXHA 1TF0A 1E7IA 4ZBRA 2XSIA 2XVUA 3TDLA 2I30A
chains in the Genus database with same CATH superfamily
1VZSA 2ROHA 2BXFA 2XVVA 5DQFA 4OTUA 2XVUA 1MUSA 1E7GA 2QMCA 4OR0A 4BY9C 2EFEA 4HGKA 2Z8KA 3B9LA 4BKEA 5DBYA 4F5SA 2Z8IA 1E7FA 5ID7A 2BXCA 1N5UA 1J78A 1GNJA 1KXPD 4G03A 2JUHA 4L9QA 4L8UA 1TXUA 2KWFA 5D7GA 4Z69A 4EMXA 3B9MA 4GDXA 2BXEA 1KDXA 5B5TA 1GNIA 3FWBC 3GA9L 3NMUA 3NVKA 2LXTA 4K2CA 2AJEA 2Z8JA 2BXDA 3GQUA 2QHBA 2E0YA 4TQ0A 2KBZA 3GQXA 4G04A 2BXOA 2BXQA 1E7AA 4Z9OA 2YDFA 2DYOA 3A73A 3WHRA 1E7BA 2DG5A 4ZUXV 1HK3A 3TDLA 2BXMA 4WA6B 2GUTA 2EFDA 2BX8A 1HK1A 3PLAA 1IJGA 2XVQA 2LOQA 3SIVB 5IIHA 5GHKA 4IW2A 1HA2A 2QM6A 4LUFA 2XVWA 3BPJA 3JQZA 4N3ZA 2EFCA 4OTTA 4ZC6A 3H3AA 4C31B 2DBUA 4W4UB 5GIPA 2BXBA 3ECPA 1E78A 2DYMA 4JK4A 5BPKA 2BXIA 2K0NA 2LQHA 4G01A 1SB0A 1J7EA 2BXGA 3CX9A 4K71A 3KJLA 4S1YA 2LQIA 1MUHA 4GDLB 4IW1A 2BXLA 2DBWA 2BXKA 3ICXA 4F5UA 1MIVA 5IJEA 5IIXA 4L9KA 2BXPA 2I2ZA 2OZBB 1JNBA 3M99C 2DBXA 1VFIA 2NNWA 2XW0A 3W1SA 1LOTA 1BKEA 5ID9A 2VUEA 1MM8A 4LUHA 5FUOA 3SIUB 1KW2A 4DM0A 3LU7A 4OT2A 4F5TA 1H5WA 3NVIA 4ZCGA 3FNMA 4N0UD 5HOZA 5IIUA 2VUFA 3MHSB 4GG2A 1LNSA 4N0FD 3UIVA 1O9XA 4PO0A 1MIYA 4I9OA 1AO6A 4ZBKA 5IJFA 2VDBA 3A75A 3G9KD 1H9ZA 3LU8A 3SQJA 2XMOA 1E7HA 2V36A 1E7EA 3MHHB 4DHXB 3LU6A 3V03A 4E99A 4HGMB 2E0XA 1E7CA 4ZBQA 1BJ5A 3FWCC 3H37A 4MBEC 1UORA 3KIKA 2CKXA 2XW1A 5GIOA 4J2VA 1HK4A 1HK5A 1MA9A 4LB2A 5IFOA 2LXSA 3NVMA 3V08A 3VQIA 1BM0A 2NQOA 4FJCB 3JRYA 2EFHA 4LA0A 4NAWB 1HK2A 3V09A 4F5VA 4TQ1A 2AGHB 3WHQA 2BXAA 3WHSA 2BXNA 4FIPB 4LB9A 2BXHA 1MIWA 1FOUA 5IJ5A 1TF0A 1E7IA 4M70B 4ZBRA 4D7XA 4FK5B 2XSIA 5GINA 1NT2B 2OT3A 4GDKB 2I30A
chains in the Genus database with same CATH topology
1VZSA 2ROHA 2BXFA 2XVVA 5DQFA 4OTUA 2XVUA 1E7GA 2QMCA 4OR0A 4BY9C 2EFEA 4HGKA 2Z8KA 3B9LA 4BKEA 5DBYA 4F5SA 2Z8IA 1E7FA 5ID7A 2BXCA 1N5UA 1J78A 1GNJA 1KXPD 4G03A 2JUHA 4L9QA 4L8UA 1TXUA 5D7GA 4Z69A 4EMXA 3B9MA 4GDXA 2BXEA 5B5TA 1GNIA 3FWBC 3GA9L 3NMUA 3NVKA 4K2CA 2AJEA 2Z8JA 2BXDA 3GQUA 2QHBA 2E0YA 4TQ0A 2KBZA 3GQXA 4G04A 2BXOA 2BXQA 1E7AA 4Z9OA 2YDFA 2DYOA 3A73A 3WHRA 1E7BA 2DG5A 4ZUXV 1HK3A 3TDLA 2BXMA 4WA6B 2EFDA 2BX8A 1HK1A 3PLAA 1IJGA 2XVQA 2LOQA 3SIVB 5IIHA 5GHKA 4IW2A 1HA2A 2QM6A 4LUFA 2XVWA 3JQZA 4N3ZA 2EFCA 4OTTA 4ZC6A 3H3AA 4C31B 2DBUA 4W4UB 5GIPA 2BXBA 1E78A 2DYMA 4JK4A 5BPKA 2BXIA 4G01A 3V09A 1J7EA 2BXGA 3CX9A 4K71A 3KJLA 4S1YA 4GDLB 4IW1A 2BXLA 2DBWA 2BXKA 3ICXA 4F5UA 1MIVA 5IJEA 5IIXA 4L9KA 2BXPA 2I2ZA 2OZBB 1JNBA 3M99C 2DBXA 1VFIA 2NNWA 2XW0A 3W1SA 1LOTA 1BKEA 5ID9A 2VUEA 4LUHA 5FUOA 3SIUB 1KW2A 3LU7A 4OT2A 4F5TA 1H5WA 3NVIA 4ZCGA 3FNMA 4N0UD 5HOZA 5IIUA 2VUFA 3MHSB 4GG2A 1LNSA 4N0FD 3UIVA 1O9XA 4PO0A 1MIYA 1AO6A 4ZBKA 5IJFA 2VDBA 3A75A 3G9KD 1H9ZA 3LU8A 3SQJA 2XMOA 1E7HA 2V36A 1E7EA 3MHHB 4DHXB 3LU6A 3V03A 4E99A 4HGMB 2E0XA 1E7CA 4ZBQA 1BJ5A 3FWCC 3H37A 4MBEC 1UORA 3KIKA 2CKXA 2XW1A 5GIOA 4J2VA 1HK4A 1HK5A 1MA9A 4LB2A 5IFOA 3NVMA 3V08A 3VQIA 1BM0A 2NQOA 4FJCB 3JRYA 2EFHA 4LA0A 4NAWB 1HK2A 4F5VA 4TQ1A 3WHQA 2BXAA 3WHSA 2BXNA 4FIPB 4LB9A 2BXHA 1MIWA 1FOUA 5IJ5A 1TF0A 1E7IA 4M70B 4ZBRA 4FK5B 2XSIA 5GINA 1NT2B 2OT3A 4GDKB 2I30A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BXF A;  2XVV A;  5DQF A;  1E7G A;  4OR0 A;  4HGK A;  3B9L A;  4BKE A;  5DBY A;  4F5S A;  1E7F A;  5ID7 A;  2BXC A;  1N5U A;  1J78 A;  1GNJ A;  1KXP D;  4G03 A;  4L9Q A;  4L8U A;  4Z69 A;  4EMX A;  3B9M A;  2BXE A;  1GNI A;  4K2C A;  2BXD A;  4G04 A;  2BXO A;  2BXQ A;  1E7A A;  2YDF A;  3A73 A;  1E7B A;  1HK3 A;  2BXM A;  2BX8 A;  1HK1 A;  2XVQ A;  5IIH A;  5GHK A;  4IW2 A;  1HA2 A;  4LUF A;  2XVW A;  3JQZ A;  2BXB A;  1E78 A;  4JK4 A;  2BXI A;  3V09 A;  1J7E A;  2BXG A;  3CX9 A;  4K71 A;  4S1Y A;  4IW1 A;  2BXL A;  4F5U A;  2BXK A;  5IJE A;  5IIX A;  4L9K A;  2BXP A;  2I2Z A;  2XW0 A;  1LOT A;  1BKE A;  5ID9 A;  2VUE A;  4LUH A;  5FUO A;  1KW2 A;  3LU7 A;  4OT2 A;  4F5T A;  5IIU A;  4N0U D;  5HOZ A;  2VUF A;  4N0F D;  3UIV A;  1O9X A;  4PO0 A;  1AO6 A;  5IJF A;  2VDB A;  1H9Z A;  3LU8 A;  3SQJ A;  1E7H A;  1E7E A;  3LU6 A;  3V03 A;  4E99 A;  4HGM B;  1E7C A;  4ZBQ A;  1BJ5 A;  1UOR A;  2XW1 A;  4J2V A;  1HK4 A;  1HK5 A;  1MA9 A;  4LB2 A;  5IFO A;  3V08 A;  1BM0 A;  4LA0 A;  3JRY A;  1HK2 A;  4F5V A;  2BXA A;  2BXN A;  5IJ5 A;  4LB9 A;  2BXH A;  1TF0 A;  1E7I A;  4ZBR A;  2XSI A;  2XVU A;  3TDL A;  2I30 A; 
#chains in the Genus database with same CATH topology
 1VZS A;  2ROH A;  2BXF A;  2XVV A;  5DQF A;  4OTU A;  2XVU A;  1MUS A;  1E7G A;  2QMC A;  4OR0 A;  4BY9 C;  2EFE A;  4HGK A;  2Z8K A;  3B9L A;  4BKE A;  5DBY A;  4F5S A;  2Z8I A;  1E7F A;  5ID7 A;  2BXC A;  1N5U A;  1J78 A;  1GNJ A;  1KXP D;  4G03 A;  2JUH A;  4L9Q A;  4L8U A;  1TXU A;  2KWF A;  5D7G A;  4Z69 A;  4EMX A;  3B9M A;  4GDX A;  2BXE A;  1KDX A;  5B5T A;  1GNI A;  3FWB C;  3GA9 L;  3NMU A;  3NVK A;  2LXT A;  4K2C A;  2AJE A;  2Z8J A;  2BXD A;  3GQU A;  2QHB A;  2E0Y A;  4TQ0 A;  2KBZ A;  3GQX A;  4G04 A;  2BXO A;  2BXQ A;  1E7A A;  4Z9O A;  2YDF A;  2DYO A;  3A73 A;  3WHR A;  1E7B A;  2DG5 A;  4ZUX V;  1HK3 A;  3TDL A;  2BXM A;  4WA6 B;  2GUT A;  2EFD A;  2BX8 A;  1HK1 A;  3PLA A;  1IJG A;  2XVQ A;  2LOQ A;  3SIV B;  5IIH A;  5GHK A;  4IW2 A;  1HA2 A;  2QM6 A;  4LUF A;  2XVW A;  3BPJ A;  3JQZ A;  4N3Z A;  2EFC A;  4OTT A;  4ZC6 A;  3H3A A;  4C31 B;  2DBU A;  4W4U B;  5GIP A;  2BXB A;  3ECP A;  1E78 A;  2DYM A;  4JK4 A;  5BPK A;  2BXI A;  2K0N A;  2LQH A;  4G01 A;  1SB0 A;  1J7E A;  2BXG A;  3CX9 A;  4K71 A;  3KJL A;  4S1Y A;  2LQI A;  1MUH A;  4GDL B;  4IW1 A;  2BXL A;  2DBW A;  2BXK A;  3ICX A;  4F5U A;  1MIV A;  5IJE A;  5IIX A;  4L9K A;  2BXP A;  2I2Z A;  2OZB B;  1JNB A;  3M99 C;  2DBX A;  1VFI A;  2NNW A;  2XW0 A;  3W1S A;  1LOT A;  1BKE A;  5ID9 A;  2VUE A;  1MM8 A;  4LUH A;  5FUO A;  3SIU B;  1KW2 A;  4DM0 A;  3LU7 A;  4OT2 A;  4F5T A;  1H5W A;  3NVI A;  4ZCG A;  3FNM A;  4N0U D;  5HOZ A;  5IIU A;  2VUF A;  3MHS B;  4GG2 A;  1LNS A;  4N0F D;  3UIV A;  1O9X A;  4PO0 A;  1MIY A;  4I9O A;  1AO6 A;  4ZBK A;  5IJF A;  2VDB A;  3A75 A;  3G9K D;  1H9Z A;  3LU8 A;  3SQJ A;  2XMO A;  1E7H A;  2V36 A;  1E7E A;  3MHH B;  4DHX B;  3LU6 A;  3V03 A;  4E99 A;  4HGM B;  2E0X A;  1E7C A;  4ZBQ A;  1BJ5 A;  3FWC C;  3H37 A;  4MBE C;  1UOR A;  3KIK A;  2CKX A;  2XW1 A;  5GIO A;  4J2V A;  1HK4 A;  1HK5 A;  1MA9 A;  4LB2 A;  5IFO A;  2LXS A;  3NVM A;  3V08 A;  3VQI A;  1BM0 A;  2NQO A;  4FJC B;  3JRY A;  2EFH A;  4LA0 A;  4NAW B;  1HK2 A;  3V09 A;  4F5V A;  4TQ1 A;  2AGH B;  3WHQ A;  2BXA A;  3WHS A;  2BXN A;  4FIP B;  4LB9 A;  2BXH A;  1MIW A;  1FOU A;  5IJ5 A;  1TF0 A;  1E7I A;  4M70 B;  4ZBR A;  4D7X A;  4FK5 B;  2XSI A;  5GIN A;  1NT2 B;  2OT3 A;  4GDK B;  2I30 A; 
#chains in the Genus database with same CATH homology
 1VZS A;  2ROH A;  2BXF A;  2XVV A;  5DQF A;  4OTU A;  2XVU A;  1E7G A;  2QMC A;  4OR0 A;  4BY9 C;  2EFE A;  4HGK A;  2Z8K A;  3B9L A;  4BKE A;  5DBY A;  4F5S A;  2Z8I A;  1E7F A;  5ID7 A;  2BXC A;  1N5U A;  1J78 A;  1GNJ A;  1KXP D;  4G03 A;  2JUH A;  4L9Q A;  4L8U A;  1TXU A;  5D7G A;  4Z69 A;  4EMX A;  3B9M A;  4GDX A;  2BXE A;  5B5T A;  1GNI A;  3FWB C;  3GA9 L;  3NMU A;  3NVK A;  4K2C A;  2AJE A;  2Z8J A;  2BXD A;  3GQU A;  2QHB A;  2E0Y A;  4TQ0 A;  2KBZ A;  3GQX A;  4G04 A;  2BXO A;  2BXQ A;  1E7A A;  4Z9O A;  2YDF A;  2DYO A;  3A73 A;  3WHR A;  1E7B A;  2DG5 A;  4ZUX V;  1HK3 A;  3TDL A;  2BXM A;  4WA6 B;  2EFD A;  2BX8 A;  1HK1 A;  3PLA A;  1IJG A;  2XVQ A;  2LOQ A;  3SIV B;  5IIH A;  5GHK A;  4IW2 A;  1HA2 A;  2QM6 A;  4LUF A;  2XVW A;  3JQZ A;  4N3Z A;  2EFC A;  4OTT A;  4ZC6 A;  3H3A A;  4C31 B;  2DBU A;  4W4U B;  5GIP A;  2BXB A;  1E78 A;  2DYM A;  4JK4 A;  5BPK A;  2BXI A;  4G01 A;  3V09 A;  1J7E A;  2BXG A;  3CX9 A;  4K71 A;  3KJL A;  4S1Y A;  4GDL B;  4IW1 A;  2BXL A;  2DBW A;  2BXK A;  3ICX A;  4F5U A;  1MIV A;  5IJE A;  5IIX A;  4L9K A;  2BXP A;  2I2Z A;  2OZB B;  1JNB A;  3M99 C;  2DBX A;  1VFI A;  2NNW A;  2XW0 A;  3W1S A;  1LOT A;  1BKE A;  5ID9 A;  2VUE A;  4LUH A;  5FUO A;  3SIU B;  1KW2 A;  3LU7 A;  4OT2 A;  4F5T A;  1H5W A;  3NVI A;  4ZCG A;  3FNM A;  4N0U D;  5HOZ A;  5IIU A;  2VUF A;  3MHS B;  4GG2 A;  1LNS A;  4N0F D;  3UIV A;  1O9X A;  4PO0 A;  1MIY A;  1AO6 A;  4ZBK A;  5IJF A;  2VDB A;  3A75 A;  3G9K D;  1H9Z A;  3LU8 A;  3SQJ A;  2XMO A;  1E7H A;  2V36 A;  1E7E A;  3MHH B;  4DHX B;  3LU6 A;  3V03 A;  4E99 A;  4HGM B;  2E0X A;  1E7C A;  4ZBQ A;  1BJ5 A;  3FWC C;  3H37 A;  4MBE C;  1UOR A;  3KIK A;  2CKX A;  2XW1 A;  5GIO A;  4J2V A;  1HK4 A;  1HK5 A;  1MA9 A;  4LB2 A;  5IFO A;  3NVM A;  3V08 A;  3VQI A;  1BM0 A;  2NQO A;  4FJC B;  3JRY A;  2EFH A;  4LA0 A;  4NAW B;  1HK2 A;  4F5V A;  4TQ1 A;  3WHQ A;  2BXA A;  3WHS A;  2BXN A;  4FIP B;  4LB9 A;  2BXH A;  1MIW A;  1FOU A;  5IJ5 A;  1TF0 A;  1E7I A;  4M70 B;  4ZBR A;  4FK5 B;  2XSI A;  5GIN A;  1NT2 B;  2OT3 A;  4GDK B;  2I30 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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