4LA0A

X-ray study of human serum albumin complexed with bicalutamide
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
581
structure length
581
Chain Sequence
AHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural studies of several clinically important oncology drugs in complex with human serum albumin.
pubmed doi rcsb
molecule keywords SERUM ALBUMIN
molecule tags Transport protein
total genus 226
structure length 581
sequence length 581
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4la0A05
4HGKA 1MA9A 2VDBA 1GNIA 5IIXA 3V08A 4LB2A 2VUFA 1AO6A 3B9MA 4Z69A 5IFOA 4EMXA 4OT2A 5DQFA 2BXLA 2BXEA 5ID7A 1E7CA 1HK2A 1E7FA 2BXMA 3LU7A 1E7AA 1HK5A 1GNJA 5IIHA 5HOZA 2BXKA 1BJ5A 2I2ZA 1E7EA 2XVVA 3LU8A 2BXGA 4IW2A 4PO0A 5FUOA 4S1YA 3SQJA 3LU6A 1BKEA 4N0UD 3TDLA 1KW2A 3B9LA 4F5UA 2XSIA 3UIVA 4HGMB 4F5TA 4L9KA 2XVUA 2XVWA 1TF0A 1E7GA 2XW1A 4ZBRA 1HK1A 1UORA 4IW1A 4K71A 2XVQA 2XW0A 1KXPD 1E7IA 3CX9A 4LA0A 4LUFA 1N5UA 2BXCA 2BXBA 1E7HA 1LOTA 3JRYA 1HA2A 5DBYA 4BKEA 1J78A 3JQZA 4G04A 4OR0A 5IJEA 1HK3A 1J7EA 1BM0A 3V03A 2BXOA 4G03A 1E7BA 2BXHA 3V09A 5IJ5A 2BXDA 4F5SA 2BXAA 4J2VA 1H9ZA 1O9XA 2BXPA 4L8UA 5GHKA 2BXQA 3A73A 4ZBQA 4K2CA 4N0FD 2BXNA 5ID9A 2BX8A 4LB9A 5IIUA 5IJFA 4E99A 1E78A 1HK4A 2VUEA 2I30A 2BXIA 4L9QA 4LUHA 4F5VA 2BXFA 2YDFA 4JK4A
chains in the Genus database with same CATH superfamily
4FJCB 1LNSA 4HGKA 1MA9A 2VDBA 3NVKA 1GNIA 5IIXA 3VQIA 3V08A 5GIOA 4DM0A 3ICXA 4LB2A 2VUFA 1AO6A 3B9MA 3FWBC 4Z69A 3GQXA 2DG5A 5IFOA 4EMXA 4OT2A 1MIYA 5BPKA 2DBXA 3KIKA 1JNBA 2BXLA 2GUTA 5DQFA 3NMUA 2BXEA 4GDKB 5HOZA 3H3AA 1E7CA 5ID7A 1HK2A 1E7FA 2BXMA 3LU7A 1VFIA 4I9OA 1E7AA 1HK5A 5GHKA 1GNJA 4FIPB 4W4UB 4C31B 1SB0A 5IIHA 4ZBKA 2BXKA 2QMCA 1BJ5A 2I2ZA 1E7EA 2XVVA 2E0YA 2BXGA 3LU8A 2DYOA 3M99C 4IW2A 4PO0A 5FUOA 3SIVB 4ZCGA 3WHSA 4S1YA 5B5TA 2JUHA 3SQJA 4N3ZA 3LU6A 3BPJA 3NVIA 1BKEA 4N0UD 4OTUA 3TDLA 4OTTA 2V36A 3WHRA 1KW2A 2E0XA 3MHHB 3W1SA 3B9LA 3MHSB 2EFDA 3FWCC 3KJLA 4M70B 4FK5B 4F5UA 2XSIA 3UIVA 3GQUA 3ECPA 3WHQA 2QM6A 1MUHA 4HGMB 4F5TA 4GDXA 1IJGA 4L9KA 2XVUA 2LQIA 2EFEA 2XVWA 1TF0A 1E7GA 2XW1A 4ZBRA 1HK1A 1UORA 4IW1A 3PLAA 2LXSA 4K71A 2XVQA 5GINA 3A75A 2LXTA 2Z8KA 2EFCA 2XW0A 1KXPD 2NQOA 2OZBB 2CKXA 1E7IA 3CX9A 2K0NA 2NNWA 3G9KD 4LA0A 2AJEA 1N5UA 4LUFA 2BXCA 1MUSA 2BXBA 1E7HA 1LOTA 2LOQA 3JRYA 1HA2A 3H37A 5DBYA 4BKEA 4GDLB 4DHXB 1J78A 1MM8A 3JQZA 1KDXA 4G04A 4OR0A 5IJEA 1H5WA 1HK3A 2DBUA 4GG2A 1J7EA 4Z9OA 4ZUXV 1MIWA 1BM0A 3SIUB 3V03A 2BXOA 4WA6B 4BY9C 2ROHA 3GA9L 4G03A 1E7BA 2BXHA 2OT3A 1MIVA 5D7GA 5IJ5A 3V09A 2BXDA 2DBWA 2Z8IA 2EFHA 4F5SA 2BXAA 4J2VA 1H9ZA 1O9XA 2BXPA 4L8UA 3NVMA 2BXQA 2AGHB 3A73A 4ZC6A 4K2CA 4ZBQA 2QHBA 4N0FD 2BXNA 4NAWB 4TQ1A 5ID9A 1NT2B 2KBZA 4MBEC 2BX8A 4LB9A 4JK4A 3FNMA 5IIUA 5IJFA 4G01A 4E99A 1E78A 2DYMA 1HK4A 2KWFA 2I30A 2VUEA 2XMOA 2BXIA 1FOUA 2LQHA 1TXUA 4L9QA 4LUHA 4D7XA 4F5VA 5GIPA 2BXFA 4TQ0A 2Z8JA 2YDFA 1VZSA
chains in the Genus database with same CATH topology
4FJCB 1LNSA 4HGKA 1MA9A 2VDBA 3NVKA 1GNIA 5IIXA 3VQIA 3V08A 5GIOA 3ICXA 4LB2A 2VUFA 1AO6A 3B9MA 3FWBC 4Z69A 3GQXA 2DG5A 5IFOA 4EMXA 4OT2A 1MIYA 5BPKA 2DBXA 3KIKA 1JNBA 2BXLA 5DQFA 3NMUA 2BXEA 4GDKB 5HOZA 3H3AA 1E7CA 5ID7A 1HK2A 1E7FA 2BXMA 3LU7A 1VFIA 1E7AA 1HK5A 5GHKA 1GNJA 4FIPB 4W4UB 4C31B 5IIHA 4ZBKA 2BXKA 2QMCA 1BJ5A 2I2ZA 1E7EA 2XVVA 2E0YA 2BXGA 3LU8A 2DYOA 3M99C 4IW2A 4PO0A 5FUOA 3SIVB 4ZCGA 3WHSA 4S1YA 5B5TA 2JUHA 3SQJA 4N3ZA 3LU6A 3NVIA 1BKEA 4N0UD 4OTUA 3TDLA 4OTTA 2V36A 3WHRA 1KW2A 2E0XA 3MHHB 3W1SA 3B9LA 3MHSB 2EFDA 3FWCC 3KJLA 4M70B 4FK5B 4F5UA 2XSIA 3UIVA 3GQUA 3WHQA 2QM6A 4HGMB 4F5TA 4GDXA 1IJGA 4L9KA 2XVUA 2EFEA 2XVWA 1TF0A 1E7GA 2XW1A 4ZBRA 1HK1A 1UORA 4IW1A 3PLAA 4K71A 2XVQA 5GINA 3A75A 2Z8KA 2EFCA 2XW0A 1KXPD 2NQOA 2OZBB 2CKXA 1E7IA 3CX9A 4LA0A 2NNWA 3G9KD 2AJEA 1N5UA 4LUFA 2BXCA 2BXBA 1E7HA 1LOTA 2LOQA 3JRYA 1HA2A 3H37A 5DBYA 4BKEA 4GDLB 4DHXB 1J78A 3JQZA 4G04A 4OR0A 5IJEA 1H5WA 1HK3A 2DBUA 4GG2A 1J7EA 4Z9OA 4ZUXV 1MIWA 1BM0A 3SIUB 3V03A 2BXOA 4WA6B 4BY9C 2ROHA 3GA9L 4G03A 1E7BA 2BXHA 2OT3A 1MIVA 5D7GA 5IJ5A 3V09A 2BXDA 2DBWA 2Z8IA 2EFHA 4F5SA 2BXAA 4J2VA 1H9ZA 1O9XA 2BXPA 4L8UA 3NVMA 2BXQA 3A73A 4ZC6A 4ZBQA 4K2CA 2QHBA 4N0FD 2BXNA 4NAWB 4TQ1A 5ID9A 1NT2B 2KBZA 4MBEC 2BX8A 4LB9A 4JK4A 3FNMA 5IIUA 5IJFA 4G01A 4E99A 1E78A 2DYMA 1HK4A 2VUEA 2I30A 2XMOA 2BXIA 1FOUA 1TXUA 4L9QA 4LUHA 4F5VA 5GIPA 2BXFA 4TQ0A 2Z8JA 2YDFA 1VZSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HGK A;  1MA9 A;  2VDB A;  1GNI A;  5IIX A;  3V08 A;  4LB2 A;  2VUF A;  1AO6 A;  3B9M A;  4Z69 A;  5IFO A;  4EMX A;  4OT2 A;  5DQF A;  2BXL A;  2BXE A;  5ID7 A;  1E7C A;  1HK2 A;  1E7F A;  2BXM A;  3LU7 A;  1E7A A;  1HK5 A;  1GNJ A;  5IIH A;  5HOZ A;  2BXK A;  1BJ5 A;  2I2Z A;  1E7E A;  2XVV A;  3LU8 A;  2BXG A;  4IW2 A;  4PO0 A;  5FUO A;  4S1Y A;  3SQJ A;  3LU6 A;  1BKE A;  4N0U D;  3TDL A;  1KW2 A;  3B9L A;  4F5U A;  2XSI A;  3UIV A;  4HGM B;  4F5T A;  4L9K A;  2XVU A;  2XVW A;  1TF0 A;  1E7G A;  2XW1 A;  4ZBR A;  1HK1 A;  1UOR A;  4IW1 A;  4K71 A;  2XVQ A;  2XW0 A;  1KXP D;  1E7I A;  3CX9 A;  4LA0 A;  4LUF A;  1N5U A;  2BXC A;  2BXB A;  1E7H A;  1LOT A;  3JRY A;  1HA2 A;  5DBY A;  4BKE A;  1J78 A;  3JQZ A;  4G04 A;  4OR0 A;  5IJE A;  1HK3 A;  1J7E A;  1BM0 A;  3V03 A;  2BXO A;  4G03 A;  1E7B A;  2BXH A;  3V09 A;  5IJ5 A;  2BXD A;  4F5S A;  2BXA A;  4J2V A;  1H9Z A;  1O9X A;  2BXP A;  4L8U A;  5GHK A;  2BXQ A;  3A73 A;  4ZBQ A;  4K2C A;  4N0F D;  2BXN A;  5ID9 A;  2BX8 A;  4LB9 A;  5IIU A;  5IJF A;  4E99 A;  1E78 A;  1HK4 A;  2VUE A;  2I30 A;  2BXI A;  4L9Q A;  4LUH A;  4F5V A;  2BXF A;  2YDF A;  4JK4 A; 
#chains in the Genus database with same CATH topology
 4FJC B;  1LNS A;  4HGK A;  1MA9 A;  2VDB A;  3NVK A;  1GNI A;  5IIX A;  3VQI A;  3V08 A;  5GIO A;  4DM0 A;  3ICX A;  4LB2 A;  2VUF A;  1AO6 A;  3B9M A;  3FWB C;  4Z69 A;  3GQX A;  2DG5 A;  5IFO A;  4EMX A;  4OT2 A;  1MIY A;  5BPK A;  2DBX A;  3KIK A;  1JNB A;  2BXL A;  2GUT A;  5DQF A;  3NMU A;  2BXE A;  4GDK B;  5HOZ A;  3H3A A;  1E7C A;  5ID7 A;  1HK2 A;  1E7F A;  2BXM A;  3LU7 A;  1VFI A;  4I9O A;  1E7A A;  1HK5 A;  5GHK A;  1GNJ A;  4FIP B;  4W4U B;  4C31 B;  1SB0 A;  5IIH A;  4ZBK A;  2BXK A;  2QMC A;  1BJ5 A;  2I2Z A;  1E7E A;  2XVV A;  2E0Y A;  2BXG A;  3LU8 A;  2DYO A;  3M99 C;  4IW2 A;  4PO0 A;  5FUO A;  3SIV B;  4ZCG A;  3WHS A;  4S1Y A;  5B5T A;  2JUH A;  3SQJ A;  4N3Z A;  3LU6 A;  3BPJ A;  3NVI A;  1BKE A;  4N0U D;  4OTU A;  3TDL A;  4OTT A;  2V36 A;  3WHR A;  1KW2 A;  2E0X A;  3MHH B;  3W1S A;  3B9L A;  3MHS B;  2EFD A;  3FWC C;  3KJL A;  4M70 B;  4FK5 B;  4F5U A;  2XSI A;  3UIV A;  3GQU A;  3ECP A;  3WHQ A;  2QM6 A;  1MUH A;  4HGM B;  4F5T A;  4GDX A;  1IJG A;  4L9K A;  2XVU A;  2LQI A;  2EFE A;  2XVW A;  1TF0 A;  1E7G A;  2XW1 A;  4ZBR A;  1HK1 A;  1UOR A;  4IW1 A;  3PLA A;  2LXS A;  4K71 A;  2XVQ A;  5GIN A;  3A75 A;  2LXT A;  2Z8K A;  2EFC A;  2XW0 A;  1KXP D;  2NQO A;  2OZB B;  2CKX A;  1E7I A;  3CX9 A;  2K0N A;  2NNW A;  3G9K D;  4LA0 A;  2AJE A;  1N5U A;  4LUF A;  2BXC A;  1MUS A;  2BXB A;  1E7H A;  1LOT A;  2LOQ A;  3JRY A;  1HA2 A;  3H37 A;  5DBY A;  4BKE A;  4GDL B;  4DHX B;  1J78 A;  1MM8 A;  3JQZ A;  1KDX A;  4G04 A;  4OR0 A;  5IJE A;  1H5W A;  1HK3 A;  2DBU A;  4GG2 A;  1J7E A;  4Z9O A;  4ZUX V;  1MIW A;  1BM0 A;  3SIU B;  3V03 A;  2BXO A;  4WA6 B;  4BY9 C;  2ROH A;  3GA9 L;  4G03 A;  1E7B A;  2BXH A;  2OT3 A;  1MIV A;  5D7G A;  5IJ5 A;  3V09 A;  2BXD A;  2DBW A;  2Z8I A;  2EFH A;  4F5S A;  2BXA A;  4J2V A;  1H9Z A;  1O9X A;  2BXP A;  4L8U A;  3NVM A;  2BXQ A;  2AGH B;  3A73 A;  4ZC6 A;  4K2C A;  4ZBQ A;  2QHB A;  4N0F D;  2BXN A;  4NAW B;  4TQ1 A;  5ID9 A;  1NT2 B;  2KBZ A;  4MBE C;  2BX8 A;  4LB9 A;  4JK4 A;  3FNM A;  5IIU A;  5IJF A;  4G01 A;  4E99 A;  1E78 A;  2DYM A;  1HK4 A;  2KWF A;  2I30 A;  2VUE A;  2XMO A;  2BXI A;  1FOU A;  2LQH A;  1TXU A;  4L9Q A;  4LUH A;  4D7X A;  4F5V A;  5GIP A;  2BXF A;  4TQ0 A;  2Z8J A;  2YDF A;  1VZS A; 
#chains in the Genus database with same CATH homology
 4FJC B;  1LNS A;  4HGK A;  1MA9 A;  2VDB A;  3NVK A;  1GNI A;  5IIX A;  3VQI A;  3V08 A;  5GIO A;  3ICX A;  4LB2 A;  2VUF A;  1AO6 A;  3B9M A;  3FWB C;  4Z69 A;  3GQX A;  2DG5 A;  5IFO A;  4EMX A;  4OT2 A;  1MIY A;  5BPK A;  2DBX A;  3KIK A;  1JNB A;  2BXL A;  5DQF A;  3NMU A;  2BXE A;  4GDK B;  5HOZ A;  3H3A A;  1E7C A;  5ID7 A;  1HK2 A;  1E7F A;  2BXM A;  3LU7 A;  1VFI A;  1E7A A;  1HK5 A;  5GHK A;  1GNJ A;  4FIP B;  4W4U B;  4C31 B;  5IIH A;  4ZBK A;  2BXK A;  2QMC A;  1BJ5 A;  2I2Z A;  1E7E A;  2XVV A;  2E0Y A;  2BXG A;  3LU8 A;  2DYO A;  3M99 C;  4IW2 A;  4PO0 A;  5FUO A;  3SIV B;  4ZCG A;  3WHS A;  4S1Y A;  5B5T A;  2JUH A;  3SQJ A;  4N3Z A;  3LU6 A;  3NVI A;  1BKE A;  4N0U D;  4OTU A;  3TDL A;  4OTT A;  2V36 A;  3WHR A;  1KW2 A;  2E0X A;  3MHH B;  3W1S A;  3B9L A;  3MHS B;  2EFD A;  3FWC C;  3KJL A;  4M70 B;  4FK5 B;  4F5U A;  2XSI A;  3UIV A;  3GQU A;  3WHQ A;  2QM6 A;  4HGM B;  4F5T A;  4GDX A;  1IJG A;  4L9K A;  2XVU A;  2EFE A;  2XVW A;  1TF0 A;  1E7G A;  2XW1 A;  4ZBR A;  1HK1 A;  1UOR A;  4IW1 A;  3PLA A;  4K71 A;  2XVQ A;  5GIN A;  3A75 A;  2Z8K A;  2EFC A;  2XW0 A;  1KXP D;  2NQO A;  2OZB B;  2CKX A;  1E7I A;  3CX9 A;  4LA0 A;  2NNW A;  3G9K D;  2AJE A;  1N5U A;  4LUF A;  2BXC A;  2BXB A;  1E7H A;  1LOT A;  2LOQ A;  3JRY A;  1HA2 A;  3H37 A;  5DBY A;  4BKE A;  4GDL B;  4DHX B;  1J78 A;  3JQZ A;  4G04 A;  4OR0 A;  5IJE A;  1H5W A;  1HK3 A;  2DBU A;  4GG2 A;  1J7E A;  4Z9O A;  4ZUX V;  1MIW A;  1BM0 A;  3SIU B;  3V03 A;  2BXO A;  4WA6 B;  4BY9 C;  2ROH A;  3GA9 L;  4G03 A;  1E7B A;  2BXH A;  2OT3 A;  1MIV A;  5D7G A;  5IJ5 A;  3V09 A;  2BXD A;  2DBW A;  2Z8I A;  2EFH A;  4F5S A;  2BXA A;  4J2V A;  1H9Z A;  1O9X A;  2BXP A;  4L8U A;  3NVM A;  2BXQ A;  3A73 A;  4ZC6 A;  4ZBQ A;  4K2C A;  2QHB A;  4N0F D;  2BXN A;  4NAW B;  4TQ1 A;  5ID9 A;  1NT2 B;  2KBZ A;  4MBE C;  2BX8 A;  4LB9 A;  4JK4 A;  3FNM A;  5IIU A;  5IJF A;  4G01 A;  4E99 A;  1E78 A;  2DYM A;  1HK4 A;  2VUE A;  2I30 A;  2XMO A;  2BXI A;  1FOU A;  1TXU A;  4L9Q A;  4LUH A;  4F5V A;  5GIP A;  2BXF A;  4TQ0 A;  2Z8J A;  2YDF A;  1VZS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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