4LB2A

X-ray study of human serum albumin complexed with idarubicin
Total Genus 218
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural studies of several clinically important oncology drugs in complex with human serum albumin.
pubmed doi rcsb
molecule keywords SERUM ALBUMIN
molecule tags Transport protein
total genus 218
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4lb2A05
4E99A 2XVWA 5DBYA 2BXLA 4K71A 1HK3A 4ZBQA 2BXOA 1E7GA 1LOTA 3B9MA 3LU6A 1AO6A 2BXQA 3LU8A 1BM0A 2VUEA 2XVQA 2BXFA 1E7CA 5IJFA 1E7HA 4LUHA 1BKEA 5IJ5A 5IFOA 3B9LA 4OR0A 3UIVA 5IIHA 4LB2A 4OT2A 5IIXA 2XW1A 4K2CA 5ID7A 1J7EA 2BXPA 5DQFA 4LUFA 4EMXA 4L9QA 2BXIA 2BXGA 1MA9A 2BXNA 5FUOA 5HOZA 2I30A 1TF0A 3TDLA 1HA2A 2VDBA 4F5TA 2VUFA 4IW2A 2XW0A 1GNJA 4ZBRA 4F5SA 4PO0A 3V03A 1E7AA 1E78A 1J78A 1N5UA 1BJ5A 1KW2A 3A73A 4HGKA 4F5VA 1E7EA 4L8UA 2XVUA 4N0FD 1GNIA 5GHKA 5ID9A 2BXEA 4JK4A 2BX8A 3V09A 4IW1A 3JQZA 1H9ZA 1E7FA 5IJEA 2YDFA 3V08A 2XSIA 4J2VA 2BXHA 4F5UA 2BXDA 3JRYA 4BKEA 4Z69A 4L9KA 2BXMA 1KXPD 3LU7A 4S1YA 5IIUA 2I2ZA 2BXCA 1HK1A 1O9XA 4G04A 4HGMB 1E7IA 1E7BA 2BXBA 2BXAA 1HK5A 4LA0A 1HK4A 2XVVA 4LB9A 3CX9A 1HK2A 3SQJA 4G03A 4N0UD 1UORA 2BXKA
chains in the Genus database with same CATH superfamily
4E99A 2XVWA 4N3ZA 5DBYA 3MHSB 4ZBKA 4D7XA 2BXLA 1MUSA 4K71A 1HK3A 4ZBQA 2BXOA 2DBUA 1FOUA 2XMOA 3KJLA 1MIWA 1E7GA 1LOTA 1MUHA 3WHSA 3B9MA 3LU6A 4C31B 1AO6A 2KWFA 2BXQA 2OT3A 4DHXB 4MBEC 5BPKA 2DG5A 3LU8A 1BM0A 2AGHB 3M99C 2VUEA 5D7GA 2XVQA 2BXFA 5GINA 2LXSA 5GIPA 1E7CA 5IJFA 1E7HA 1LNSA 4LUHA 1BKEA 5IJ5A 3NVMA 4TQ0A 3H37A 4OTTA 5IFOA 4DM0A 3B9LA 3G9KD 4OR0A 1MIYA 2K0NA 3UIVA 1SB0A 2NNWA 5IIHA 2OZBB 2LOQA 4LB2A 4OT2A 3NVIA 3KIKA 4ZCGA 3ICXA 5IIXA 1JNBA 2XW1A 4K2CA 5ID7A 2JUHA 4G01A 2QHBA 1J7EA 2BXPA 3GQUA 5DQFA 4LUFA 4EMXA 2EFEA 4L9QA 2BXIA 2BXGA 1MA9A 2EFHA 2BXNA 2Z8KA 5HOZA 5FUOA 2I30A 1TF0A 4NAWB 3TDLA 3WHQA 1IJGA 1HA2A 2LQIA 2VDBA 4F5TA 2VUFA 4IW2A 2XW0A 1GNJA 4ZBRA 3MHHB 4BY9C 2E0XA 3WHRA 4F5SA 2LQHA 3GQXA 4FIPB 2GUTA 4PO0A 3V03A 2DYOA 2DYMA 2KBZA 1E7AA 4TQ1A 3ECPA 2DBXA 1E78A 2LXTA 1J78A 1N5UA 1BJ5A 4WA6B 1KW2A 4M70B 2EFCA 3SIUB 3A73A 3H3AA 4GDXA 1VZSA 1KDXA 2CKXA 4HGKA 4F5VA 1E7EA 1TXUA 4L8UA 2XVUA 4N0FD 1GNIA 5GHKA 4FJCB 2QM6A 5ID9A 2BXEA 4GDKB 4JK4A 4ZUXV 2BX8A 3V09A 5B5TA 1NT2B 4IW1A 3JQZA 1H9ZA 2EFDA 1E7FA 5IJEA 2YDFA 3FNMA 1H5WA 3V08A 2V36A 2XSIA 2QMCA 3GA9L 4Z9OA 2NQOA 4J2VA 2BXHA 4F5UA 2BXDA 2E0YA 3FWBC 4FK5B 3JRYA 4GDLB 4I9OA 4BKEA 4Z69A 3A75A 1VFIA 2ROHA 3NMUA 4L9KA 3PLAA 2BXMA 1KXPD 3LU7A 4S1YA 3W1SA 2I2ZA 5IIUA 2BXCA 1HK1A 1O9XA 4G04A 4W4UB 4HGMB 1E7IA 3NVKA 2Z8JA 1E7BA 2BXBA 2BXAA 1HK5A 4LA0A 3BPJA 1HK4A 2Z8IA 3SIVB 4GG2A 4ZC6A 1MM8A 2XVVA 4LB9A 3VQIA 5GIOA 3CX9A 3FWCC 1HK2A 3SQJA 1MIVA 4G03A 4OTUA 4N0UD 2AJEA 1UORA 2DBWA 2BXKA
chains in the Genus database with same CATH topology
4E99A 2XVWA 4N3ZA 5DBYA 3MHSB 4ZBKA 2BXLA 4K71A 1HK3A 4ZBQA 2BXOA 2DBUA 1FOUA 2XMOA 3KJLA 1MIWA 1E7GA 1LOTA 3WHSA 3B9MA 3LU6A 4C31B 1AO6A 2BXQA 2OT3A 4DHXB 4MBEC 5BPKA 2DG5A 3LU8A 1BM0A 3M99C 2VUEA 5D7GA 2XVQA 2BXFA 5GINA 5GIPA 1E7CA 5IJFA 1E7HA 1LNSA 4LUHA 1BKEA 5IJ5A 3NVMA 4TQ0A 3H37A 4OTTA 5IFOA 3B9LA 3G9KD 4OR0A 1MIYA 3UIVA 2NNWA 5IIHA 2OZBB 2LOQA 4LB2A 4OT2A 3NVIA 3KIKA 4ZCGA 3ICXA 5IIXA 1JNBA 2XW1A 4K2CA 5ID7A 2JUHA 4G01A 2QHBA 1J7EA 2BXPA 3GQUA 5DQFA 4LUFA 4EMXA 2EFEA 4L9QA 2BXIA 2BXGA 1MA9A 2EFHA 2BXNA 2Z8KA 5HOZA 5FUOA 2I30A 1TF0A 4NAWB 3TDLA 3WHQA 1IJGA 1HA2A 2VDBA 4F5TA 2VUFA 4IW2A 2XW0A 1GNJA 4ZBRA 3MHHB 4BY9C 2E0XA 3WHRA 4F5SA 3GQXA 4FIPB 4PO0A 3V03A 2DYOA 2DYMA 2KBZA 1E7AA 4TQ1A 2DBXA 1E78A 4WA6B 1J78A 1N5UA 1BJ5A 1KW2A 4M70B 2EFCA 3SIUB 3A73A 3H3AA 4GDXA 1VZSA 2CKXA 4HGKA 4F5VA 1E7EA 1TXUA 4L8UA 2XVUA 4N0FD 1GNIA 5GHKA 4FJCB 2QM6A 5ID9A 2BXEA 4GDKB 4JK4A 4ZUXV 2BX8A 3V09A 5B5TA 1NT2B 4IW1A 3JQZA 1H9ZA 2EFDA 1E7FA 5IJEA 2YDFA 3FNMA 1H5WA 3V08A 2V36A 2XSIA 2QMCA 3GA9L 4Z9OA 2NQOA 4J2VA 2BXHA 4F5UA 2BXDA 2E0YA 3FWBC 4FK5B 3JRYA 4GDLB 4BKEA 4Z69A 3A75A 1VFIA 2ROHA 3NMUA 4L9KA 3PLAA 2BXMA 1KXPD 3LU7A 4S1YA 3W1SA 2I2ZA 5IIUA 2BXCA 1HK1A 1O9XA 4G04A 4W4UB 4HGMB 1E7IA 3NVKA 2Z8JA 1E7BA 2BXBA 2BXAA 1HK5A 4LA0A 1HK4A 2Z8IA 3SIVB 4GG2A 4ZC6A 2XVVA 4LB9A 3VQIA 5GIOA 3CX9A 3FWCC 1HK2A 3SQJA 1MIVA 4G03A 4OTUA 4N0UD 2AJEA 1UORA 2DBWA 2BXKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E99 A;  2XVW A;  5DBY A;  2BXL A;  4K71 A;  1HK3 A;  4ZBQ A;  2BXO A;  1E7G A;  1LOT A;  3B9M A;  3LU6 A;  1AO6 A;  2BXQ A;  3LU8 A;  1BM0 A;  2VUE A;  2XVQ A;  2BXF A;  1E7C A;  5IJF A;  1E7H A;  4LUH A;  1BKE A;  5IJ5 A;  5IFO A;  3B9L A;  4OR0 A;  3UIV A;  5IIH A;  4LB2 A;  4OT2 A;  5IIX A;  2XW1 A;  4K2C A;  5ID7 A;  1J7E A;  2BXP A;  5DQF A;  4LUF A;  4EMX A;  4L9Q A;  2BXI A;  2BXG A;  1MA9 A;  2BXN A;  5FUO A;  5HOZ A;  2I30 A;  1TF0 A;  3TDL A;  1HA2 A;  2VDB A;  4F5T A;  2VUF A;  4IW2 A;  2XW0 A;  1GNJ A;  4ZBR A;  4F5S A;  4PO0 A;  3V03 A;  1E7A A;  1E78 A;  1J78 A;  1N5U A;  1BJ5 A;  1KW2 A;  3A73 A;  4HGK A;  4F5V A;  1E7E A;  4L8U A;  2XVU A;  4N0F D;  1GNI A;  5GHK A;  5ID9 A;  2BXE A;  4JK4 A;  2BX8 A;  3V09 A;  4IW1 A;  3JQZ A;  1H9Z A;  1E7F A;  5IJE A;  2YDF A;  3V08 A;  2XSI A;  4J2V A;  2BXH A;  4F5U A;  2BXD A;  3JRY A;  4BKE A;  4Z69 A;  4L9K A;  2BXM A;  1KXP D;  3LU7 A;  4S1Y A;  5IIU A;  2I2Z A;  2BXC A;  1HK1 A;  1O9X A;  4G04 A;  4HGM B;  1E7I A;  1E7B A;  2BXB A;  2BXA A;  1HK5 A;  4LA0 A;  1HK4 A;  2XVV A;  4LB9 A;  3CX9 A;  1HK2 A;  3SQJ A;  4G03 A;  4N0U D;  1UOR A;  2BXK A; 
#chains in the Genus database with same CATH topology
 4E99 A;  2XVW A;  4N3Z A;  5DBY A;  3MHS B;  4ZBK A;  4D7X A;  2BXL A;  1MUS A;  4K71 A;  1HK3 A;  4ZBQ A;  2BXO A;  2DBU A;  1FOU A;  2XMO A;  3KJL A;  1MIW A;  1E7G A;  1LOT A;  1MUH A;  3WHS A;  3B9M A;  3LU6 A;  4C31 B;  1AO6 A;  2KWF A;  2BXQ A;  2OT3 A;  4DHX B;  4MBE C;  5BPK A;  2DG5 A;  3LU8 A;  1BM0 A;  2AGH B;  3M99 C;  2VUE A;  5D7G A;  2XVQ A;  2BXF A;  5GIN A;  2LXS A;  5GIP A;  1E7C A;  5IJF A;  1E7H A;  1LNS A;  4LUH A;  1BKE A;  5IJ5 A;  3NVM A;  4TQ0 A;  3H37 A;  4OTT A;  5IFO A;  4DM0 A;  3B9L A;  3G9K D;  4OR0 A;  1MIY A;  2K0N A;  3UIV A;  1SB0 A;  2NNW A;  5IIH A;  2OZB B;  2LOQ A;  4LB2 A;  4OT2 A;  3NVI A;  3KIK A;  4ZCG A;  3ICX A;  5IIX A;  1JNB A;  2XW1 A;  4K2C A;  5ID7 A;  2JUH A;  4G01 A;  2QHB A;  1J7E A;  2BXP A;  3GQU A;  5DQF A;  4LUF A;  4EMX A;  2EFE A;  4L9Q A;  2BXI A;  2BXG A;  1MA9 A;  2EFH A;  2BXN A;  2Z8K A;  5HOZ A;  5FUO A;  2I30 A;  1TF0 A;  4NAW B;  3TDL A;  3WHQ A;  1IJG A;  1HA2 A;  2LQI A;  2VDB A;  4F5T A;  2VUF A;  4IW2 A;  2XW0 A;  1GNJ A;  4ZBR A;  3MHH B;  4BY9 C;  2E0X A;  3WHR A;  4F5S A;  2LQH A;  3GQX A;  4FIP B;  2GUT A;  4PO0 A;  3V03 A;  2DYO A;  2DYM A;  2KBZ A;  1E7A A;  4TQ1 A;  3ECP A;  2DBX A;  1E78 A;  2LXT A;  1J78 A;  1N5U A;  1BJ5 A;  4WA6 B;  1KW2 A;  4M70 B;  2EFC A;  3SIU B;  3A73 A;  3H3A A;  4GDX A;  1VZS A;  1KDX A;  2CKX A;  4HGK A;  4F5V A;  1E7E A;  1TXU A;  4L8U A;  2XVU A;  4N0F D;  1GNI A;  5GHK A;  4FJC B;  2QM6 A;  5ID9 A;  2BXE A;  4GDK B;  4JK4 A;  4ZUX V;  2BX8 A;  3V09 A;  5B5T A;  1NT2 B;  4IW1 A;  3JQZ A;  1H9Z A;  2EFD A;  1E7F A;  5IJE A;  2YDF A;  3FNM A;  1H5W A;  3V08 A;  2V36 A;  2XSI A;  2QMC A;  3GA9 L;  4Z9O A;  2NQO A;  4J2V A;  2BXH A;  4F5U A;  2BXD A;  2E0Y A;  3FWB C;  4FK5 B;  3JRY A;  4GDL B;  4I9O A;  4BKE A;  4Z69 A;  3A75 A;  1VFI A;  2ROH A;  3NMU A;  4L9K A;  3PLA A;  2BXM A;  1KXP D;  3LU7 A;  4S1Y A;  3W1S A;  2I2Z A;  5IIU A;  2BXC A;  1HK1 A;  1O9X A;  4G04 A;  4W4U B;  4HGM B;  1E7I A;  3NVK A;  2Z8J A;  1E7B A;  2BXB A;  2BXA A;  1HK5 A;  4LA0 A;  3BPJ A;  1HK4 A;  2Z8I A;  3SIV B;  4GG2 A;  4ZC6 A;  1MM8 A;  2XVV A;  4LB9 A;  3VQI A;  5GIO A;  3CX9 A;  3FWC C;  1HK2 A;  3SQJ A;  1MIV A;  4G03 A;  4OTU A;  4N0U D;  2AJE A;  1UOR A;  2DBW A;  2BXK A; 
#chains in the Genus database with same CATH homology
 4E99 A;  2XVW A;  4N3Z A;  5DBY A;  3MHS B;  4ZBK A;  2BXL A;  4K71 A;  1HK3 A;  4ZBQ A;  2BXO A;  2DBU A;  1FOU A;  2XMO A;  3KJL A;  1MIW A;  1E7G A;  1LOT A;  3WHS A;  3B9M A;  3LU6 A;  4C31 B;  1AO6 A;  2BXQ A;  2OT3 A;  4DHX B;  4MBE C;  5BPK A;  2DG5 A;  3LU8 A;  1BM0 A;  3M99 C;  2VUE A;  5D7G A;  2XVQ A;  2BXF A;  5GIN A;  5GIP A;  1E7C A;  5IJF A;  1E7H A;  1LNS A;  4LUH A;  1BKE A;  5IJ5 A;  3NVM A;  4TQ0 A;  3H37 A;  4OTT A;  5IFO A;  3B9L A;  3G9K D;  4OR0 A;  1MIY A;  3UIV A;  2NNW A;  5IIH A;  2OZB B;  2LOQ A;  4LB2 A;  4OT2 A;  3NVI A;  3KIK A;  4ZCG A;  3ICX A;  5IIX A;  1JNB A;  2XW1 A;  4K2C A;  5ID7 A;  2JUH A;  4G01 A;  2QHB A;  1J7E A;  2BXP A;  3GQU A;  5DQF A;  4LUF A;  4EMX A;  2EFE A;  4L9Q A;  2BXI A;  2BXG A;  1MA9 A;  2EFH A;  2BXN A;  2Z8K A;  5HOZ A;  5FUO A;  2I30 A;  1TF0 A;  4NAW B;  3TDL A;  3WHQ A;  1IJG A;  1HA2 A;  2VDB A;  4F5T A;  2VUF A;  4IW2 A;  2XW0 A;  1GNJ A;  4ZBR A;  3MHH B;  4BY9 C;  2E0X A;  3WHR A;  4F5S A;  3GQX A;  4FIP B;  4PO0 A;  3V03 A;  2DYO A;  2DYM A;  2KBZ A;  1E7A A;  4TQ1 A;  2DBX A;  1E78 A;  4WA6 B;  1J78 A;  1N5U A;  1BJ5 A;  1KW2 A;  4M70 B;  2EFC A;  3SIU B;  3A73 A;  3H3A A;  4GDX A;  1VZS A;  2CKX A;  4HGK A;  4F5V A;  1E7E A;  1TXU A;  4L8U A;  2XVU A;  4N0F D;  1GNI A;  5GHK A;  4FJC B;  2QM6 A;  5ID9 A;  2BXE A;  4GDK B;  4JK4 A;  4ZUX V;  2BX8 A;  3V09 A;  5B5T A;  1NT2 B;  4IW1 A;  3JQZ A;  1H9Z A;  2EFD A;  1E7F A;  5IJE A;  2YDF A;  3FNM A;  1H5W A;  3V08 A;  2V36 A;  2XSI A;  2QMC A;  3GA9 L;  4Z9O A;  2NQO A;  4J2V A;  2BXH A;  4F5U A;  2BXD A;  2E0Y A;  3FWB C;  4FK5 B;  3JRY A;  4GDL B;  4BKE A;  4Z69 A;  3A75 A;  1VFI A;  2ROH A;  3NMU A;  4L9K A;  3PLA A;  2BXM A;  1KXP D;  3LU7 A;  4S1Y A;  3W1S A;  2I2Z A;  5IIU A;  2BXC A;  1HK1 A;  1O9X A;  4G04 A;  4W4U B;  4HGM B;  1E7I A;  3NVK A;  2Z8J A;  1E7B A;  2BXB A;  2BXA A;  1HK5 A;  4LA0 A;  1HK4 A;  2Z8I A;  3SIV B;  4GG2 A;  4ZC6 A;  2XVV A;  4LB9 A;  3VQI A;  5GIO A;  3CX9 A;  3FWC C;  1HK2 A;  3SQJ A;  1MIV A;  4G03 A;  4OTU A;  4N0U D;  2AJE A;  1UOR A;  2DBW A;  2BXK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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