4N0FD

Human fcrn complexed with human serum albumin
Total Genus 223
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
223
sequence length
583
structure length
583
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms.
pubmed doi rcsb
molecule keywords IgG receptor FcRn large subunit p51
molecule tags Immune system
total genus 223
structure length 583
sequence length 583
chains with identical sequence G, J, M
ec nomenclature
pdb deposition date 2013-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0fD05
2I30A 2BXBA 2BXHA 1HK3A 3B9MA 3LU8A 2XVWA 4F5SA 4IW1A 1E7IA 1BJ5A 2XVUA 4F5VA 2XVVA 4LUFA 5HOZA 4E99A 4L9KA 2YDFA 5GHKA 1GNIA 5DBYA 4N0FD 4LB2A 4OT2A 5IIXA 2BXMA 2VUEA 4EMXA 1KXPD 1E7EA 5DQFA 2BXPA 3CX9A 1J78A 2BXKA 1E7BA 4S1YA 2BXCA 4G03A 2BXIA 4N0UD 1E7HA 1E7GA 1LOTA 4LA0A 1H9ZA 2BXLA 4L9QA 5ID7A 4F5TA 2BXNA 3B9LA 4IW2A 4BKEA 4ZBQA 4K2CA 3A73A 5IJEA 2XSIA 1HK4A 1AO6A 1BKEA 3TDLA 1N5UA 5FUOA 2BXDA 4JK4A 4K71A 5IIHA 2VDBA 4G04A 3JQZA 1E7AA 4PO0A 2BXEA 2BXOA 1E78A 1O9XA 4HGMB 2BXGA 3SQJA 4F5UA 1KW2A 2BXQA 4ZBRA 1MA9A 2XW0A 3V09A 4J2VA 2BX8A 1HK2A 1HK1A 4L8UA 1J7EA 4LUHA 2XVQA 5ID9A 1E7CA 2BXAA 3V03A 4LB9A 3UIVA 1BM0A 5IFOA 3V08A 4OR0A 5IIUA 3JRYA 1E7FA 3LU7A 1UORA 4HGKA 1GNJA 5IJFA 2I2ZA 2BXFA 1HA2A 3LU6A 1TF0A 2XW1A 1HK5A 5IJ5A 2VUFA 4Z69A
chains in the Genus database with same CATH superfamily
2I30A 2LOQA 2BXBA 2BXHA 4I9OA 1HK3A 3B9MA 3LU8A 2XVWA 4ZUXV 2Z8IA 4F5SA 4IW1A 1E7IA 5BPKA 1BJ5A 2E0XA 2XVUA 4F5VA 3NMUA 2Z8KA 2XVVA 4LUFA 5HOZA 4E99A 2EFCA 4L9KA 3WHQA 2YDFA 1MIWA 4FK5B 3WHRA 5GHKA 1GNIA 5DBYA 2CKXA 4N0FD 4LB2A 3MHSB 2EFHA 3WHSA 4OTTA 4OT2A 2BXMA 5IIXA 2AJEA 2KBZA 2QM6A 2VUEA 4EMXA 3ECPA 1KXPD 1TXUA 1E7EA 1MUSA 2NQOA 3NVIA 5DQFA 2BXPA 3CX9A 3GQXA 1J78A 2DBWA 4ZBKA 2BXKA 1E7BA 4S1YA 2BXCA 2V36A 4G03A 2QMCA 2BXIA 1JNBA 3VQIA 4N0UD 1E7HA 1E7GA 1LOTA 3FNMA 3ICXA 4TQ1A 4LA0A 4GG2A 4BY9C 1IJGA 1H9ZA 2BXLA 2K0NA 3SIVB 3G9KD 4L9QA 2KWFA 4GDXA 5ID7A 4F5TA 2BXNA 3B9LA 4ZC6A 4IW2A 4BKEA 4ZBQA 4K2CA 3A73A 2E0YA 5IJEA 2XSIA 1HK4A 1MIVA 2NNWA 1BKEA 5B5TA 1AO6A 3TDLA 2GUTA 1N5UA 3NVMA 4GDKB 5FUOA 2OZBB 2BXDA 4JK4A 4ZCGA 4DM0A 2EFEA 3KIKA 2DBXA 4K71A 1LNSA 3GA9L 3M99C 2VDBA 4G04A 2DG5A 4WA6B 3W1SA 5IIHA 4N3ZA 3JQZA 4MBEC 1E7AA 4PO0A 2BXEA 2JUHA 2BXOA 4W4UB 1E78A 1O9XA 1VZSA 2EFDA 4HGMB 3FWCC 2BXGA 2QHBA 4TQ0A 3SQJA 3GQUA 4F5UA 4C31B 1KW2A 3H37A 2BXQA 4ZBRA 1MA9A 3A75A 2XW0A 3SIUB 2ROHA 5GIPA 4G01A 3V09A 4J2VA 2BX8A 4DHXB 1HK2A 1HK1A 4Z9OA 4L8UA 1H5WA 1J7EA 4LUHA 2XVQA 5D7GA 1MIYA 5ID9A 1E7CA 2DYMA 3H3AA 2BXAA 3KJLA 4LB9A 3V03A 1MM8A 3UIVA 3FWBC 1BM0A 5GIOA 5IFOA 3V08A 1NT2B 4OR0A 5IIUA 2DBUA 1KDXA 3JRYA 1E7FA 2AGHB 2LQHA 3LU7A 1UORA 2DYOA 1FOUA 1GNJA 4GDLB 4HGKA 4NAWB 3PLAA 5IJFA 1SB0A 2I2ZA 2BXFA 1HA2A 2LXTA 2LQIA 3MHHB 4D7XA 3LU6A 1TF0A 2OT3A 2XW1A 2LXSA 4FIPB 2XMOA 1HK5A 1VFIA 4OTUA 1MUHA 3NVKA 5IJ5A 4M70B 2VUFA 3BPJA 5GINA 4FJCB 4Z69A 2Z8JA
chains in the Genus database with same CATH topology
2I30A 2LOQA 2BXBA 2BXHA 1HK3A 3B9MA 3LU8A 2XVWA 4ZUXV 2Z8IA 4F5SA 4IW1A 1E7IA 5BPKA 1BJ5A 2E0XA 2XVUA 4F5VA 3NMUA 2Z8KA 2XVVA 4LUFA 5HOZA 4E99A 2EFCA 4L9KA 3WHQA 2YDFA 1MIWA 4FK5B 3WHRA 5GHKA 1GNIA 5DBYA 2CKXA 4N0FD 4LB2A 3MHSB 2EFHA 3WHSA 4OTTA 4OT2A 2BXMA 5IIXA 2AJEA 2KBZA 2QM6A 2VUEA 4EMXA 1KXPD 1TXUA 1E7EA 2NQOA 3NVIA 5DQFA 2BXPA 3CX9A 3GQXA 1J78A 2DBWA 4ZBKA 2BXKA 1E7BA 4S1YA 2BXCA 2V36A 4G03A 2QMCA 2BXIA 1JNBA 3VQIA 4N0UD 1E7HA 1E7GA 1LOTA 3FNMA 3ICXA 4TQ1A 4LA0A 4GG2A 4BY9C 1IJGA 1H9ZA 2BXLA 3SIVB 3G9KD 4L9QA 4GDXA 5ID7A 4F5TA 2BXNA 3B9LA 4ZC6A 4IW2A 4BKEA 4ZBQA 4K2CA 3A73A 2E0YA 5IJEA 2XSIA 1HK4A 1MIVA 2NNWA 1BKEA 5B5TA 1AO6A 3TDLA 1N5UA 3NVMA 4GDKB 5FUOA 2OZBB 2BXDA 4JK4A 4ZCGA 2EFEA 3KIKA 2DBXA 4K71A 1LNSA 3GA9L 3M99C 2VDBA 4G04A 2DG5A 4WA6B 3W1SA 5IIHA 4N3ZA 3JQZA 4MBEC 1E7AA 4PO0A 2BXEA 2JUHA 2BXOA 4W4UB 1E78A 1O9XA 1VZSA 2EFDA 4HGMB 3FWCC 2BXGA 2QHBA 4TQ0A 3SQJA 3GQUA 4F5UA 4C31B 1KW2A 3H37A 2BXQA 4ZBRA 1MA9A 3A75A 2XW0A 3SIUB 2ROHA 5GIPA 4G01A 3V09A 4J2VA 2BX8A 4DHXB 1HK2A 1HK1A 4Z9OA 4L8UA 1H5WA 1J7EA 4LUHA 2XVQA 5D7GA 1MIYA 5ID9A 1E7CA 2DYMA 3H3AA 2BXAA 3KJLA 4LB9A 3V03A 3UIVA 3FWBC 1BM0A 5GIOA 5IFOA 3V08A 1NT2B 4OR0A 5IIUA 2DBUA 3JRYA 1E7FA 4GDLB 3LU7A 1UORA 2DYOA 1FOUA 1GNJA 4HGKA 4NAWB 3PLAA 5IJFA 2I2ZA 2BXFA 1HA2A 3MHHB 3LU6A 1TF0A 2OT3A 2XW1A 4FIPB 2XMOA 1HK5A 1VFIA 4OTUA 3NVKA 5IJ5A 4M70B 2VUFA 5GINA 4FJCB 4Z69A 2Z8JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I30 A;  2BXB A;  2BXH A;  1HK3 A;  3B9M A;  3LU8 A;  2XVW A;  4F5S A;  4IW1 A;  1E7I A;  1BJ5 A;  2XVU A;  4F5V A;  2XVV A;  4LUF A;  5HOZ A;  4E99 A;  4L9K A;  2YDF A;  5GHK A;  1GNI A;  5DBY A;  4N0F D;  4LB2 A;  4OT2 A;  5IIX A;  2BXM A;  2VUE A;  4EMX A;  1KXP D;  1E7E A;  5DQF A;  2BXP A;  3CX9 A;  1J78 A;  2BXK A;  1E7B A;  4S1Y A;  2BXC A;  4G03 A;  2BXI A;  4N0U D;  1E7H A;  1E7G A;  1LOT A;  4LA0 A;  1H9Z A;  2BXL A;  4L9Q A;  5ID7 A;  4F5T A;  2BXN A;  3B9L A;  4IW2 A;  4BKE A;  4ZBQ A;  4K2C A;  3A73 A;  5IJE A;  2XSI A;  1HK4 A;  1AO6 A;  1BKE A;  3TDL A;  1N5U A;  5FUO A;  2BXD A;  4JK4 A;  4K71 A;  5IIH A;  2VDB A;  4G04 A;  3JQZ A;  1E7A A;  4PO0 A;  2BXE A;  2BXO A;  1E78 A;  1O9X A;  4HGM B;  2BXG A;  3SQJ A;  4F5U A;  1KW2 A;  2BXQ A;  4ZBR A;  1MA9 A;  2XW0 A;  3V09 A;  4J2V A;  2BX8 A;  1HK2 A;  1HK1 A;  4L8U A;  1J7E A;  4LUH A;  2XVQ A;  5ID9 A;  1E7C A;  2BXA A;  3V03 A;  4LB9 A;  3UIV A;  1BM0 A;  5IFO A;  3V08 A;  4OR0 A;  5IIU A;  3JRY A;  1E7F A;  3LU7 A;  1UOR A;  4HGK A;  1GNJ A;  5IJF A;  2I2Z A;  2BXF A;  1HA2 A;  3LU6 A;  1TF0 A;  2XW1 A;  1HK5 A;  5IJ5 A;  2VUF A;  4Z69 A; 
#chains in the Genus database with same CATH topology
 2I30 A;  2LOQ A;  2BXB A;  2BXH A;  4I9O A;  1HK3 A;  3B9M A;  3LU8 A;  2XVW A;  4ZUX V;  2Z8I A;  4F5S A;  4IW1 A;  1E7I A;  5BPK A;  1BJ5 A;  2E0X A;  2XVU A;  4F5V A;  3NMU A;  2Z8K A;  2XVV A;  4LUF A;  5HOZ A;  4E99 A;  2EFC A;  4L9K A;  3WHQ A;  2YDF A;  1MIW A;  4FK5 B;  3WHR A;  5GHK A;  1GNI A;  5DBY A;  2CKX A;  4N0F D;  4LB2 A;  3MHS B;  2EFH A;  3WHS A;  4OTT A;  4OT2 A;  2BXM A;  5IIX A;  2AJE A;  2KBZ A;  2QM6 A;  2VUE A;  4EMX A;  3ECP A;  1KXP D;  1TXU A;  1E7E A;  1MUS A;  2NQO A;  3NVI A;  5DQF A;  2BXP A;  3CX9 A;  3GQX A;  1J78 A;  2DBW A;  4ZBK A;  2BXK A;  1E7B A;  4S1Y A;  2BXC A;  2V36 A;  4G03 A;  2QMC A;  2BXI A;  1JNB A;  3VQI A;  4N0U D;  1E7H A;  1E7G A;  1LOT A;  3FNM A;  3ICX A;  4TQ1 A;  4LA0 A;  4GG2 A;  4BY9 C;  1IJG A;  1H9Z A;  2BXL A;  2K0N A;  3SIV B;  3G9K D;  4L9Q A;  2KWF A;  4GDX A;  5ID7 A;  4F5T A;  2BXN A;  3B9L A;  4ZC6 A;  4IW2 A;  4BKE A;  4ZBQ A;  4K2C A;  3A73 A;  2E0Y A;  5IJE A;  2XSI A;  1HK4 A;  1MIV A;  2NNW A;  1BKE A;  5B5T A;  1AO6 A;  3TDL A;  2GUT A;  1N5U A;  3NVM A;  4GDK B;  5FUO A;  2OZB B;  2BXD A;  4JK4 A;  4ZCG A;  4DM0 A;  2EFE A;  3KIK A;  2DBX A;  4K71 A;  1LNS A;  3GA9 L;  3M99 C;  2VDB A;  4G04 A;  2DG5 A;  4WA6 B;  3W1S A;  5IIH A;  4N3Z A;  3JQZ A;  4MBE C;  1E7A A;  4PO0 A;  2BXE A;  2JUH A;  2BXO A;  4W4U B;  1E78 A;  1O9X A;  1VZS A;  2EFD A;  4HGM B;  3FWC C;  2BXG A;  2QHB A;  4TQ0 A;  3SQJ A;  3GQU A;  4F5U A;  4C31 B;  1KW2 A;  3H37 A;  2BXQ A;  4ZBR A;  1MA9 A;  3A75 A;  2XW0 A;  3SIU B;  2ROH A;  5GIP A;  4G01 A;  3V09 A;  4J2V A;  2BX8 A;  4DHX B;  1HK2 A;  1HK1 A;  4Z9O A;  4L8U A;  1H5W A;  1J7E A;  4LUH A;  2XVQ A;  5D7G A;  1MIY A;  5ID9 A;  1E7C A;  2DYM A;  3H3A A;  2BXA A;  3KJL A;  4LB9 A;  3V03 A;  1MM8 A;  3UIV A;  3FWB C;  1BM0 A;  5GIO A;  5IFO A;  3V08 A;  1NT2 B;  4OR0 A;  5IIU A;  2DBU A;  1KDX A;  3JRY A;  1E7F A;  2AGH B;  2LQH A;  3LU7 A;  1UOR A;  2DYO A;  1FOU A;  1GNJ A;  4GDL B;  4HGK A;  4NAW B;  3PLA A;  5IJF A;  1SB0 A;  2I2Z A;  2BXF A;  1HA2 A;  2LXT A;  2LQI A;  3MHH B;  4D7X A;  3LU6 A;  1TF0 A;  2OT3 A;  2XW1 A;  2LXS A;  4FIP B;  2XMO A;  1HK5 A;  1VFI A;  4OTU A;  1MUH A;  3NVK A;  5IJ5 A;  4M70 B;  2VUF A;  3BPJ A;  5GIN A;  4FJC B;  4Z69 A;  2Z8J A; 
#chains in the Genus database with same CATH homology
 2I30 A;  2LOQ A;  2BXB A;  2BXH A;  1HK3 A;  3B9M A;  3LU8 A;  2XVW A;  4ZUX V;  2Z8I A;  4F5S A;  4IW1 A;  1E7I A;  5BPK A;  1BJ5 A;  2E0X A;  2XVU A;  4F5V A;  3NMU A;  2Z8K A;  2XVV A;  4LUF A;  5HOZ A;  4E99 A;  2EFC A;  4L9K A;  3WHQ A;  2YDF A;  1MIW A;  4FK5 B;  3WHR A;  5GHK A;  1GNI A;  5DBY A;  2CKX A;  4N0F D;  4LB2 A;  3MHS B;  2EFH A;  3WHS A;  4OTT A;  4OT2 A;  2BXM A;  5IIX A;  2AJE A;  2KBZ A;  2QM6 A;  2VUE A;  4EMX A;  1KXP D;  1TXU A;  1E7E A;  2NQO A;  3NVI A;  5DQF A;  2BXP A;  3CX9 A;  3GQX A;  1J78 A;  2DBW A;  4ZBK A;  2BXK A;  1E7B A;  4S1Y A;  2BXC A;  2V36 A;  4G03 A;  2QMC A;  2BXI A;  1JNB A;  3VQI A;  4N0U D;  1E7H A;  1E7G A;  1LOT A;  3FNM A;  3ICX A;  4TQ1 A;  4LA0 A;  4GG2 A;  4BY9 C;  1IJG A;  1H9Z A;  2BXL A;  3SIV B;  3G9K D;  4L9Q A;  4GDX A;  5ID7 A;  4F5T A;  2BXN A;  3B9L A;  4ZC6 A;  4IW2 A;  4BKE A;  4ZBQ A;  4K2C A;  3A73 A;  2E0Y A;  5IJE A;  2XSI A;  1HK4 A;  1MIV A;  2NNW A;  1BKE A;  5B5T A;  1AO6 A;  3TDL A;  1N5U A;  3NVM A;  4GDK B;  5FUO A;  2OZB B;  2BXD A;  4JK4 A;  4ZCG A;  2EFE A;  3KIK A;  2DBX A;  4K71 A;  1LNS A;  3GA9 L;  3M99 C;  2VDB A;  4G04 A;  2DG5 A;  4WA6 B;  3W1S A;  5IIH A;  4N3Z A;  3JQZ A;  4MBE C;  1E7A A;  4PO0 A;  2BXE A;  2JUH A;  2BXO A;  4W4U B;  1E78 A;  1O9X A;  1VZS A;  2EFD A;  4HGM B;  3FWC C;  2BXG A;  2QHB A;  4TQ0 A;  3SQJ A;  3GQU A;  4F5U A;  4C31 B;  1KW2 A;  3H37 A;  2BXQ A;  4ZBR A;  1MA9 A;  3A75 A;  2XW0 A;  3SIU B;  2ROH A;  5GIP A;  4G01 A;  3V09 A;  4J2V A;  2BX8 A;  4DHX B;  1HK2 A;  1HK1 A;  4Z9O A;  4L8U A;  1H5W A;  1J7E A;  4LUH A;  2XVQ A;  5D7G A;  1MIY A;  5ID9 A;  1E7C A;  2DYM A;  3H3A A;  2BXA A;  3KJL A;  4LB9 A;  3V03 A;  3UIV A;  3FWB C;  1BM0 A;  5GIO A;  5IFO A;  3V08 A;  1NT2 B;  4OR0 A;  5IIU A;  2DBU A;  3JRY A;  1E7F A;  4GDL B;  3LU7 A;  1UOR A;  2DYO A;  1FOU A;  1GNJ A;  4HGK A;  4NAW B;  3PLA A;  5IJF A;  2I2Z A;  2BXF A;  1HA2 A;  3MHH B;  3LU6 A;  1TF0 A;  2OT3 A;  2XW1 A;  4FIP B;  2XMO A;  1HK5 A;  1VFI A;  4OTU A;  3NVK A;  5IJ5 A;  4M70 B;  2VUF A;  5GIN A;  4FJC B;  4Z69 A;  2Z8J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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