4N0UD

Ternary complex between neonatal fc receptor, serum albumin and fc
Total Genus 219
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
219
sequence length
583
structure length
583
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms.
pubmed doi rcsb
molecule keywords IgG receptor FcRn large subunit p51
molecule tags Dna binding protein
source organism Homo sapiens
total genus 219
structure length 583
sequence length 583
ec nomenclature
pdb deposition date 2013-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0uD03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0uD02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0uD04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0uD01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0uD06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4n0uD05
1BM0A 4E99A 3JQZA 4S1YA 3LU6A 4F5TA 4ZBQA 4JK4A 2BXQA 2XVUA 3V08A 1KW2A 1MA9A 2BXKA 4F5VA 1E7GA 2XSIA 1J7EA 5ID7A 1HK1A 1GNJA 5IIUA 4G04A 2VUEA 2XW1A 1HK4A 3A73A 5IJ5A 4HGKA 5ID9A 2BXGA 1HK5A 5IFOA 5IJFA 1LOTA 5IIHA 4Z69A 4L9QA 1E7EA 2BX8A 3SQJA 2YDFA 1UORA 5GHKA 2BXMA 3B9MA 4IW2A 2XW0A 2BXOA 2BXAA 3V09A 1HA2A 2BXLA 3B9LA 3V03A 1N5UA 3UIVA 4BKEA 2XVQA 2BXNA 2I30A 4LB9A 1E7IA 1E7HA 4N0FD 1GNIA 2BXIA 1TF0A 4K2CA 4F5UA 1E7CA 4G03A 4IW1A 2VDBA 2VUFA 2BXFA 2XVVA 1E7FA 1O9XA 4PO0A 3LU7A 4HGMB 2XVWA 3LU8A 4LB2A 1BJ5A 4ZBRA 1BKEA 5IIXA 2BXDA 3CX9A 4L9KA 5FUOA 1J78A 1E78A 1H9ZA 4OT2A 4LA0A 4J2VA 2BXHA 4K71A 2BXCA 3TDLA 2BXPA 2BXEA 1AO6A 5HOZA 4LUFA 4OR0A 5DBYA 1HK3A 4L8UA 4F5SA 5DQFA 1E7BA 1KXPD 2I2ZA 4LUHA 1E7AA 3JRYA 4N0UD 4EMXA 1HK2A 2BXBA 5IJEA
chains in the Genus database with same CATH superfamily
3SIUB 1BM0A 4Z9OA 4E99A 2LOQA 3JQZA 3KJLA 3NVIA 4S1YA 2Z8JA 3LU6A 2ROHA 3WHSA 4F5TA 1MUHA 3M99C 2KBZA 4ZUXV 4ZBQA 3GA9L 2LXTA 4JK4A 2BXQA 2GUTA 2XVUA 3V08A 1NT2B 1MUSA 2LQIA 1KW2A 1MA9A 2BXKA 4D7XA 4F5VA 4M70B 3NVMA 1E7GA 2XSIA 1J7EA 4NAWB 4BY9C 1H5WA 2QMCA 3G9KD 4GDXA 5ID7A 1HK1A 1GNJA 2K0NA 4FK5B 5IIUA 4G04A 2VUEA 2XW1A 2V36A 4DHXB 1HK4A 2QHBA 2OZBB 2Z8KA 1JNBA 2E0YA 3A73A 5IJ5A 4HGKA 4OTTA 3W1SA 3H37A 1MIYA 5ID9A 2DG5A 2BXGA 1HK5A 3BPJA 2CKXA 5IFOA 5IJFA 1LOTA 5IIHA 3WHQA 4I9OA 4OTUA 4Z69A 5GIOA 4N3ZA 1KDXA 1VZSA 4ZCGA 3KIKA 4L9QA 1E7EA 2BX8A 2DBWA 2DYMA 2YDFA 3SQJA 4FJCB 1UORA 4WA6B 5GHKA 2BXMA 3B9MA 4MBEC 3A75A 2XW0A 2BXOA 2BXAA 4IW2A 1HA2A 3V09A 3SIVB 2BXLA 3B9LA 3V03A 1N5UA 3GQXA 4ZC6A 3UIVA 4BKEA 2XVQA 2BXNA 2DBXA 2I30A 4LB9A 1E7IA 3VQIA 2LXSA 1E7HA 1MIWA 4N0FD 3ICXA 4C31B 2DYOA 5BPKA 1GNIA 2BXIA 4G01A 5GIPA 4FIPB 2EFDA 1TF0A 3ECPA 4K2CA 2DBUA 2AGHB 1IJGA 2E0XA 5D7GA 1E7CA 4G03A 4F5UA 1MM8A 4IW1A 2VDBA 2VUFA 3WHRA 2BXFA 2KWFA 2XVVA 1E7FA 5GINA 3H3AA 1O9XA 4PO0A 3LU7A 4HGMB 2XVWA 4ZBKA 3LU8A 4LB2A 2EFEA 1BJ5A 3MHHB 4TQ1A 4ZBRA 1BKEA 1LNSA 5IIXA 2BXDA 3CX9A 4GDKB 4L9KA 2AJEA 5FUOA 1J78A 5B5TA 1E78A 4W4UB 1H9ZA 4OT2A 4LA0A 4J2VA 2BXHA 4GG2A 4K71A 2BXCA 3FWCC 2BXPA 3TDLA 2BXEA 2Z8IA 1AO6A 1MIVA 2JUHA 4LUFA 5HOZA 1VFIA 4OR0A 1SB0A 5DBYA 1HK3A 2XMOA 2NNWA 4L8UA 5DQFA 4F5SA 1E7BA 3GQUA 1KXPD 2I2ZA 3NVKA 2EFHA 3FWBC 3NMUA 4LUHA 3MHSB 2OT3A 4DM0A 1E7AA 2NQOA 3JRYA 2LQHA 2QM6A 4GDLB 4N0UD 4EMXA 1HK2A 1TXUA 1FOUA 3PLAA 4TQ0A 2BXBA 3FNMA 5IJEA 2EFCA
chains in the Genus database with same CATH topology
3SIUB 1BM0A 4Z9OA 4E99A 2LOQA 3JQZA 3KJLA 3NVIA 4S1YA 2Z8JA 3LU6A 2ROHA 3WHSA 4F5TA 3M99C 2KBZA 4ZUXV 4ZBQA 3GA9L 4JK4A 2BXQA 2XVUA 3V08A 1NT2B 1KW2A 1MA9A 2BXKA 4F5VA 4M70B 3NVMA 1E7GA 2XSIA 1J7EA 4NAWB 4BY9C 1H5WA 2QMCA 3G9KD 4GDXA 5ID7A 1HK1A 1GNJA 4FK5B 5IIUA 4G04A 2VUEA 2XW1A 2V36A 4DHXB 1HK4A 2QHBA 2OZBB 2Z8KA 1JNBA 2E0YA 3A73A 5IJ5A 4HGKA 4OTTA 3W1SA 3H37A 1MIYA 5ID9A 2DG5A 2BXGA 1HK5A 5IFOA 2CKXA 5IJFA 1LOTA 5IIHA 3WHQA 4OTUA 4Z69A 5GIOA 4N3ZA 1VZSA 4ZCGA 3KIKA 4L9QA 1E7EA 2BX8A 2DBWA 2DYMA 2YDFA 3SQJA 4FJCB 1UORA 4WA6B 5GHKA 2BXMA 3B9MA 4MBEC 3A75A 2XW0A 2BXOA 2BXAA 4IW2A 1HA2A 3V09A 3SIVB 2BXLA 3B9LA 3V03A 1N5UA 3GQXA 4ZC6A 3UIVA 4BKEA 2XVQA 2BXNA 2DBXA 2I30A 4LB9A 1E7IA 3VQIA 1E7HA 1MIWA 4N0FD 3ICXA 4C31B 2DYOA 5BPKA 1GNIA 2BXIA 4G01A 5GIPA 4FIPB 2EFDA 1TF0A 4K2CA 2DBUA 1IJGA 2E0XA 5D7GA 1E7CA 4G03A 4F5UA 4IW1A 2VDBA 2VUFA 3WHRA 2BXFA 2XVVA 1E7FA 5GINA 3H3AA 1O9XA 4PO0A 3LU7A 4HGMB 2XVWA 4ZBKA 3LU8A 4LB2A 2EFEA 1BJ5A 3MHHB 4TQ1A 4ZBRA 1BKEA 1LNSA 5IIXA 2BXDA 3CX9A 4GDKB 4L9KA 2AJEA 5FUOA 1J78A 5B5TA 1E78A 4W4UB 1H9ZA 4OT2A 4LA0A 4J2VA 2BXHA 4GG2A 4K71A 2BXCA 3FWCC 2BXPA 3TDLA 2BXEA 2Z8IA 1AO6A 1MIVA 2JUHA 4LUFA 5HOZA 1VFIA 4OR0A 5DBYA 1HK3A 2XMOA 2NNWA 4L8UA 5DQFA 4F5SA 1E7BA 3GQUA 1KXPD 2I2ZA 3NVKA 2EFHA 3FWBC 3NMUA 4LUHA 3MHSB 2OT3A 1E7AA 2NQOA 3JRYA 2QM6A 4GDLB 4N0UD 4EMXA 1HK2A 1TXUA 1FOUA 3PLAA 4TQ0A 2BXBA 3FNMA 5IJEA 2EFCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BM0 A;  4E99 A;  3JQZ A;  4S1Y A;  3LU6 A;  4F5T A;  4ZBQ A;  4JK4 A;  2BXQ A;  2XVU A;  3V08 A;  1KW2 A;  1MA9 A;  2BXK A;  4F5V A;  1E7G A;  2XSI A;  1J7E A;  5ID7 A;  1HK1 A;  1GNJ A;  5IIU A;  4G04 A;  2VUE A;  2XW1 A;  1HK4 A;  3A73 A;  5IJ5 A;  4HGK A;  5ID9 A;  2BXG A;  1HK5 A;  5IFO A;  5IJF A;  1LOT A;  5IIH A;  4Z69 A;  4L9Q A;  1E7E A;  2BX8 A;  3SQJ A;  2YDF A;  1UOR A;  5GHK A;  2BXM A;  3B9M A;  4IW2 A;  2XW0 A;  2BXO A;  2BXA A;  3V09 A;  1HA2 A;  2BXL A;  3B9L A;  3V03 A;  1N5U A;  3UIV A;  4BKE A;  2XVQ A;  2BXN A;  2I30 A;  4LB9 A;  1E7I A;  1E7H A;  4N0F D;  1GNI A;  2BXI A;  1TF0 A;  4K2C A;  4F5U A;  1E7C A;  4G03 A;  4IW1 A;  2VDB A;  2VUF A;  2BXF A;  2XVV A;  1E7F A;  1O9X A;  4PO0 A;  3LU7 A;  4HGM B;  2XVW A;  3LU8 A;  4LB2 A;  1BJ5 A;  4ZBR A;  1BKE A;  5IIX A;  2BXD A;  3CX9 A;  4L9K A;  5FUO A;  1J78 A;  1E78 A;  1H9Z A;  4OT2 A;  4LA0 A;  4J2V A;  2BXH A;  4K71 A;  2BXC A;  3TDL A;  2BXP A;  2BXE A;  1AO6 A;  5HOZ A;  4LUF A;  4OR0 A;  5DBY A;  1HK3 A;  4L8U A;  4F5S A;  5DQF A;  1E7B A;  1KXP D;  2I2Z A;  4LUH A;  1E7A A;  3JRY A;  4N0U D;  4EMX A;  1HK2 A;  2BXB A;  5IJE A; 
#chains in the Genus database with same CATH topology
 3SIU B;  1BM0 A;  4Z9O A;  4E99 A;  2LOQ A;  3JQZ A;  3KJL A;  3NVI A;  4S1Y A;  2Z8J A;  3LU6 A;  2ROH A;  3WHS A;  4F5T A;  1MUH A;  3M99 C;  2KBZ A;  4ZUX V;  4ZBQ A;  3GA9 L;  2LXT A;  4JK4 A;  2BXQ A;  2GUT A;  2XVU A;  3V08 A;  1NT2 B;  1MUS A;  2LQI A;  1KW2 A;  1MA9 A;  2BXK A;  4D7X A;  4F5V A;  4M70 B;  3NVM A;  1E7G A;  2XSI A;  1J7E A;  4NAW B;  4BY9 C;  1H5W A;  2QMC A;  3G9K D;  4GDX A;  5ID7 A;  1HK1 A;  1GNJ A;  2K0N A;  4FK5 B;  5IIU A;  4G04 A;  2VUE A;  2XW1 A;  2V36 A;  4DHX B;  1HK4 A;  2QHB A;  2OZB B;  2Z8K A;  1JNB A;  2E0Y A;  3A73 A;  5IJ5 A;  4HGK A;  4OTT A;  3W1S A;  3H37 A;  1MIY A;  5ID9 A;  2DG5 A;  2BXG A;  1HK5 A;  3BPJ A;  2CKX A;  5IFO A;  5IJF A;  1LOT A;  5IIH A;  3WHQ A;  4I9O A;  4OTU A;  4Z69 A;  5GIO A;  4N3Z A;  1KDX A;  1VZS A;  4ZCG A;  3KIK A;  4L9Q A;  1E7E A;  2BX8 A;  2DBW A;  2DYM A;  2YDF A;  3SQJ A;  4FJC B;  1UOR A;  4WA6 B;  5GHK A;  2BXM A;  3B9M A;  4MBE C;  3A75 A;  2XW0 A;  2BXO A;  2BXA A;  4IW2 A;  1HA2 A;  3V09 A;  3SIV B;  2BXL A;  3B9L A;  3V03 A;  1N5U A;  3GQX A;  4ZC6 A;  3UIV A;  4BKE A;  2XVQ A;  2BXN A;  2DBX A;  2I30 A;  4LB9 A;  1E7I A;  3VQI A;  2LXS A;  1E7H A;  1MIW A;  4N0F D;  3ICX A;  4C31 B;  2DYO A;  5BPK A;  1GNI A;  2BXI A;  4G01 A;  5GIP A;  4FIP B;  2EFD A;  1TF0 A;  3ECP A;  4K2C A;  2DBU A;  2AGH B;  1IJG A;  2E0X A;  5D7G A;  1E7C A;  4G03 A;  4F5U A;  1MM8 A;  4IW1 A;  2VDB A;  2VUF A;  3WHR A;  2BXF A;  2KWF A;  2XVV A;  1E7F A;  5GIN A;  3H3A A;  1O9X A;  4PO0 A;  3LU7 A;  4HGM B;  2XVW A;  4ZBK A;  3LU8 A;  4LB2 A;  2EFE A;  1BJ5 A;  3MHH B;  4TQ1 A;  4ZBR A;  1BKE A;  1LNS A;  5IIX A;  2BXD A;  3CX9 A;  4GDK B;  4L9K A;  2AJE A;  5FUO A;  1J78 A;  5B5T A;  1E78 A;  4W4U B;  1H9Z A;  4OT2 A;  4LA0 A;  4J2V A;  2BXH A;  4GG2 A;  4K71 A;  2BXC A;  3FWC C;  2BXP A;  3TDL A;  2BXE A;  2Z8I A;  1AO6 A;  1MIV A;  2JUH A;  4LUF A;  5HOZ A;  1VFI A;  4OR0 A;  1SB0 A;  5DBY A;  1HK3 A;  2XMO A;  2NNW A;  4L8U A;  5DQF A;  4F5S A;  1E7B A;  3GQU A;  1KXP D;  2I2Z A;  3NVK A;  2EFH A;  3FWB C;  3NMU A;  4LUH A;  3MHS B;  2OT3 A;  4DM0 A;  1E7A A;  2NQO A;  3JRY A;  2LQH A;  2QM6 A;  4GDL B;  4N0U D;  4EMX A;  1HK2 A;  1TXU A;  1FOU A;  3PLA A;  4TQ0 A;  2BXB A;  3FNM A;  5IJE A;  2EFC A; 
#chains in the Genus database with same CATH homology
 3SIU B;  1BM0 A;  4Z9O A;  4E99 A;  2LOQ A;  3JQZ A;  3KJL A;  3NVI A;  4S1Y A;  2Z8J A;  3LU6 A;  2ROH A;  3WHS A;  4F5T A;  3M99 C;  2KBZ A;  4ZUX V;  4ZBQ A;  3GA9 L;  4JK4 A;  2BXQ A;  2XVU A;  3V08 A;  1NT2 B;  1KW2 A;  1MA9 A;  2BXK A;  4F5V A;  4M70 B;  3NVM A;  1E7G A;  2XSI A;  1J7E A;  4NAW B;  4BY9 C;  1H5W A;  2QMC A;  3G9K D;  4GDX A;  5ID7 A;  1HK1 A;  1GNJ A;  4FK5 B;  5IIU A;  4G04 A;  2VUE A;  2XW1 A;  2V36 A;  4DHX B;  1HK4 A;  2QHB A;  2OZB B;  2Z8K A;  1JNB A;  2E0Y A;  3A73 A;  5IJ5 A;  4HGK A;  4OTT A;  3W1S A;  3H37 A;  1MIY A;  5ID9 A;  2DG5 A;  2BXG A;  1HK5 A;  5IFO A;  2CKX A;  5IJF A;  1LOT A;  5IIH A;  3WHQ A;  4OTU A;  4Z69 A;  5GIO A;  4N3Z A;  1VZS A;  4ZCG A;  3KIK A;  4L9Q A;  1E7E A;  2BX8 A;  2DBW A;  2DYM A;  2YDF A;  3SQJ A;  4FJC B;  1UOR A;  4WA6 B;  5GHK A;  2BXM A;  3B9M A;  4MBE C;  3A75 A;  2XW0 A;  2BXO A;  2BXA A;  4IW2 A;  1HA2 A;  3V09 A;  3SIV B;  2BXL A;  3B9L A;  3V03 A;  1N5U A;  3GQX A;  4ZC6 A;  3UIV A;  4BKE A;  2XVQ A;  2BXN A;  2DBX A;  2I30 A;  4LB9 A;  1E7I A;  3VQI A;  1E7H A;  1MIW A;  4N0F D;  3ICX A;  4C31 B;  2DYO A;  5BPK A;  1GNI A;  2BXI A;  4G01 A;  5GIP A;  4FIP B;  2EFD A;  1TF0 A;  4K2C A;  2DBU A;  1IJG A;  2E0X A;  5D7G A;  1E7C A;  4G03 A;  4F5U A;  4IW1 A;  2VDB A;  2VUF A;  3WHR A;  2BXF A;  2XVV A;  1E7F A;  5GIN A;  3H3A A;  1O9X A;  4PO0 A;  3LU7 A;  4HGM B;  2XVW A;  4ZBK A;  3LU8 A;  4LB2 A;  2EFE A;  1BJ5 A;  3MHH B;  4TQ1 A;  4ZBR A;  1BKE A;  1LNS A;  5IIX A;  2BXD A;  3CX9 A;  4GDK B;  4L9K A;  2AJE A;  5FUO A;  1J78 A;  5B5T A;  1E78 A;  4W4U B;  1H9Z A;  4OT2 A;  4LA0 A;  4J2V A;  2BXH A;  4GG2 A;  4K71 A;  2BXC A;  3FWC C;  2BXP A;  3TDL A;  2BXE A;  2Z8I A;  1AO6 A;  1MIV A;  2JUH A;  4LUF A;  5HOZ A;  1VFI A;  4OR0 A;  5DBY A;  1HK3 A;  2XMO A;  2NNW A;  4L8U A;  5DQF A;  4F5S A;  1E7B A;  3GQU A;  1KXP D;  2I2Z A;  3NVK A;  2EFH A;  3FWB C;  3NMU A;  4LUH A;  3MHS B;  2OT3 A;  1E7A A;  2NQO A;  3JRY A;  2QM6 A;  4GDL B;  4N0U D;  4EMX A;  1HK2 A;  1TXU A;  1FOU A;  3PLA A;  4TQ0 A;  2BXB A;  3FNM A;  5IJE A;  2EFC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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