4Z69A

Human serum albumin complexed with palmitic acid and diclofenac
Total Genus 227
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
227
sequence length
581
structure length
581
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Serum albumin
publication title Structural basis of non-steroidal anti-inflammatory drug diclofenac binding to human serum albumin.
pubmed doi rcsb
source organism Homo sapiens
total genus 227
structure length 581
sequence length 581
chains with identical sequence I
ec nomenclature
pdb deposition date 2015-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A05
2XSIA 4LB9A 3LU8A 1J7EA 2XVUA 2XW1A 1KXPD 1H9ZA 1HK1A 1BKEA 3V03A 3SQJA 3CX9A 5HOZA 4G03A 5DBYA 2BXIA 3B9LA 4LUHA 2BXEA 5IIXA 2BXBA 2BXAA 3A73A 4F5UA 3JRYA 1E7AA 2BXOA 4ZBQA 4OT2A 4JK4A 2BXCA 1GNIA 4L9QA 4J2VA 4OR0A 2YDFA 1E7IA 1E78A 4Z69A 1E7EA 1HK3A 3V09A 2I2ZA 2BXKA 4ZBRA 2I30A 1UORA 4EMXA 3LU7A 2BXMA 2BXQA 4F5TA 4HGMB 2XW0A 2VUEA 1HK2A 1GNJA 1E7CA 4S1YA 4G04A 2XVQA 5ID7A 4LA0A 3V08A 5FUOA 5IIUA 4N0FD 1HK4A 2BXLA 5IFOA 2BXNA 4K71A 3B9MA 1E7GA 1E7FA 1MA9A 4PO0A 4IW1A 1LOTA 2VDBA 2BX8A 2VUFA 1KW2A 4HGKA 1E7BA 1O9XA 3UIVA 5IIHA 1J78A 5IJ5A 5ID9A 2BXPA 1N5UA 1BJ5A 1HA2A 1BM0A 4L8UA 4BKEA 1TF0A 5IJFA 4K2CA 2XVVA 2BXHA 1HK5A 4F5SA 2XVWA 3TDLA 5IJEA 3JQZA 4F5VA 5GHKA 5DQFA 2BXDA 4E99A 2BXGA 4L9KA 4LUFA 1E7HA 2BXFA 4N0UD 4LB2A 4IW2A 1AO6A 3LU6A
chains in the Genus database with same CATH superfamily
2XSIA 4LB9A 4G01A 3FWBC 3VQIA 3LU8A 4FIPB 1J7EA 2XVUA 5GIPA 2XW1A 1KXPD 1H9ZA 1KDXA 1HK1A 2V36A 1BKEA 3V03A 5B5TA 3SQJA 2NNWA 3CX9A 5HOZA 4M70B 3FNMA 4G03A 5DBYA 4FK5B 2BXIA 3B9LA 1SB0A 4LUHA 4TQ1A 3BPJA 2BXEA 2KBZA 3MHHB 4GDXA 1MM8A 2E0YA 4DHXB 5IIXA 2NQOA 2BXBA 2BXAA 2K0NA 3A73A 1NT2B 1H5WA 4F5UA 2DBXA 3JRYA 1E7AA 1MIVA 2BXOA 2LOQA 3NVMA 4ZBQA 3A75A 4OTTA 4OT2A 4JK4A 2BXCA 1GNIA 1LNSA 4L9QA 4J2VA 4OR0A 4C31B 2YDFA 4GDKB 3H37A 2QM6A 1E7IA 1E78A 4Z69A 1FOUA 1JNBA 3MHSB 1E7EA 1HK3A 3V09A 1VZSA 2I2ZA 1VFIA 2BXKA 2OT3A 2ROHA 3FWCC 4TQ0A 3G9KD 4Z9OA 4ZBRA 2I30A 1UORA 2CKXA 4EMXA 3LU7A 4N3ZA 3WHQA 2AJEA 4D7XA 2EFDA 2BXMA 5GIOA 2BXQA 4F5TA 4ZBKA 4HGMB 5BPKA 2QHBA 2XW0A 2VUEA 3ICXA 3LU6A 2AGHB 1HK2A 1GNJA 1E7CA 2LQHA 3GQXA 4S1YA 3H3AA 4MBEC 1MIWA 4G04A 3W1SA 1MIYA 4GG2A 2GUTA 2LXSA 2XVQA 5ID7A 4LA0A 3V08A 5FUOA 4W4UB 5IIUA 1IJGA 4N0FD 4GDLB 3NVIA 1HK4A 2BXLA 5IFOA 2BXNA 4K71A 5D7GA 2KWFA 3B9MA 1E7GA 3PLAA 2XMOA 2DBWA 1E7FA 1MA9A 4PO0A 4IW1A 1LOTA 2VDBA 3NMUA 2EFHA 2BX8A 2VUFA 4ZCGA 1KW2A 2DG5A 3M99C 4HGKA 1E7BA 1O9XA 2DYOA 3UIVA 1J78A 5IIHA 5IJ5A 2EFCA 5ID9A 2BXPA 4NAWB 2Z8KA 3KJLA 1N5UA 1BJ5A 1HA2A 1BM0A 4L8UA 4BKEA 1TF0A 5IJFA 2DYMA 4K2CA 3WHSA 3WHRA 2LXTA 1MUSA 2LQIA 2BXHA 2XVVA 4ZUXV 1HK5A 3GQUA 4F5SA 2XVWA 3NVKA 4OTUA 3TDLA 2E0XA 4I9OA 3JQZA 5IJEA 2Z8JA 2EFEA 4F5VA 4FJCB 5GHKA 5DQFA 2BXDA 4E99A 4WA6B 4BY9C 3ECPA 3SIUB 2BXGA 5GINA 1MUHA 2Z8IA 2OZBB 3KIKA 4L9KA 2DBUA 4ZC6A 4LUFA 1E7HA 2BXFA 2JUHA 3SIVB 4N0UD 1TXUA 4DM0A 4LB2A 4IW2A 1AO6A 3GA9L 2QMCA
chains in the Genus database with same CATH topology
2XSIA 4LB9A 4G01A 3FWBC 3VQIA 3LU8A 4FIPB 1J7EA 2XVUA 5GIPA 2XW1A 1KXPD 1H9ZA 1HK1A 2V36A 1BKEA 3V03A 5B5TA 3SQJA 2NNWA 3CX9A 5HOZA 4M70B 3FNMA 4G03A 5DBYA 4FK5B 2BXIA 3B9LA 4LUHA 4TQ1A 2BXEA 2KBZA 3MHHB 4GDXA 2E0YA 4DHXB 5IIXA 2NQOA 2BXBA 2BXAA 3A73A 1NT2B 1H5WA 4F5UA 2DBXA 3JRYA 1E7AA 1MIVA 2BXOA 2LOQA 3NVMA 4ZBQA 3A75A 4OTTA 4OT2A 4JK4A 2BXCA 1GNIA 1LNSA 4L9QA 4J2VA 4OR0A 4C31B 2YDFA 4GDKB 3H37A 2QM6A 1E7IA 1E78A 4Z69A 1FOUA 1JNBA 3MHSB 1E7EA 1HK3A 3V09A 1VZSA 2I2ZA 1VFIA 2BXKA 2OT3A 2ROHA 3FWCC 4TQ0A 3G9KD 4Z9OA 4ZBRA 2I30A 1UORA 2CKXA 4EMXA 3LU7A 4N3ZA 3WHQA 2AJEA 2EFDA 2BXMA 5GIOA 2BXQA 4F5TA 4ZBKA 4HGMB 5BPKA 2QHBA 2XW0A 2VUEA 3ICXA 3LU6A 3GQXA 1HK2A 1GNJA 1E7CA 4S1YA 3H3AA 4MBEC 1MIWA 4G04A 3W1SA 1MIYA 4GG2A 2XVQA 5ID7A 4LA0A 3V08A 5FUOA 4W4UB 5IIUA 1IJGA 4N0FD 4GDLB 3NVIA 1HK4A 2BXLA 5IFOA 2BXNA 4K71A 5D7GA 3B9MA 3PLAA 1E7GA 2XMOA 2DBWA 1E7FA 1MA9A 4PO0A 4IW1A 1LOTA 2VDBA 3NMUA 2EFHA 2BX8A 2VUFA 4ZCGA 1KW2A 2DG5A 3M99C 4HGKA 1E7BA 1O9XA 2DYOA 3UIVA 1J78A 5IIHA 5IJ5A 2EFCA 5ID9A 2BXPA 4NAWB 2Z8KA 3KJLA 1N5UA 1BJ5A 1HA2A 1BM0A 4L8UA 4BKEA 1TF0A 5IJFA 2DYMA 4K2CA 3WHSA 3WHRA 2XVVA 2BXHA 4ZUXV 1HK5A 3GQUA 4F5SA 2XVWA 3NVKA 4OTUA 3TDLA 2E0XA 5IJEA 3JQZA 2Z8JA 2EFEA 4F5VA 4FJCB 5GHKA 5DQFA 2BXDA 4E99A 4WA6B 4BY9C 3SIUB 2BXGA 5GINA 2Z8IA 2OZBB 3KIKA 4L9KA 2DBUA 4ZC6A 4LUFA 1E7HA 2BXFA 2JUHA 3SIVB 4N0UD 1TXUA 4LB2A 4IW2A 1AO6A 3GA9L 2QMCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XSI A;  4LB9 A;  3LU8 A;  1J7E A;  2XVU A;  2XW1 A;  1KXP D;  1H9Z A;  1HK1 A;  1BKE A;  3V03 A;  3SQJ A;  3CX9 A;  5HOZ A;  4G03 A;  5DBY A;  2BXI A;  3B9L A;  4LUH A;  2BXE A;  5IIX A;  2BXB A;  2BXA A;  3A73 A;  4F5U A;  3JRY A;  1E7A A;  2BXO A;  4ZBQ A;  4OT2 A;  4JK4 A;  2BXC A;  1GNI A;  4L9Q A;  4J2V A;  4OR0 A;  2YDF A;  1E7I A;  1E78 A;  4Z69 A;  1E7E A;  1HK3 A;  3V09 A;  2I2Z A;  2BXK A;  4ZBR A;  2I30 A;  1UOR A;  4EMX A;  3LU7 A;  2BXM A;  2BXQ A;  4F5T A;  4HGM B;  2XW0 A;  2VUE A;  1HK2 A;  1GNJ A;  1E7C A;  4S1Y A;  4G04 A;  2XVQ A;  5ID7 A;  4LA0 A;  3V08 A;  5FUO A;  5IIU A;  4N0F D;  1HK4 A;  2BXL A;  5IFO A;  2BXN A;  4K71 A;  3B9M A;  1E7G A;  1E7F A;  1MA9 A;  4PO0 A;  4IW1 A;  1LOT A;  2VDB A;  2BX8 A;  2VUF A;  1KW2 A;  4HGK A;  1E7B A;  1O9X A;  3UIV A;  5IIH A;  1J78 A;  5IJ5 A;  5ID9 A;  2BXP A;  1N5U A;  1BJ5 A;  1HA2 A;  1BM0 A;  4L8U A;  4BKE A;  1TF0 A;  5IJF A;  4K2C A;  2XVV A;  2BXH A;  1HK5 A;  4F5S A;  2XVW A;  3TDL A;  5IJE A;  3JQZ A;  4F5V A;  5GHK A;  5DQF A;  2BXD A;  4E99 A;  2BXG A;  4L9K A;  4LUF A;  1E7H A;  2BXF A;  4N0U D;  4LB2 A;  4IW2 A;  1AO6 A;  3LU6 A; 
#chains in the Genus database with same CATH topology
 2XSI A;  4LB9 A;  4G01 A;  3FWB C;  3VQI A;  3LU8 A;  4FIP B;  1J7E A;  2XVU A;  5GIP A;  2XW1 A;  1KXP D;  1H9Z A;  1KDX A;  1HK1 A;  2V36 A;  1BKE A;  3V03 A;  5B5T A;  3SQJ A;  2NNW A;  3CX9 A;  5HOZ A;  4M70 B;  3FNM A;  4G03 A;  5DBY A;  4FK5 B;  2BXI A;  3B9L A;  1SB0 A;  4LUH A;  4TQ1 A;  3BPJ A;  2BXE A;  2KBZ A;  3MHH B;  4GDX A;  1MM8 A;  2E0Y A;  4DHX B;  5IIX A;  2NQO A;  2BXB A;  2BXA A;  2K0N A;  3A73 A;  1NT2 B;  1H5W A;  4F5U A;  2DBX A;  3JRY A;  1E7A A;  1MIV A;  2BXO A;  2LOQ A;  3NVM A;  4ZBQ A;  3A75 A;  4OTT A;  4OT2 A;  4JK4 A;  2BXC A;  1GNI A;  1LNS A;  4L9Q A;  4J2V A;  4OR0 A;  4C31 B;  2YDF A;  4GDK B;  3H37 A;  2QM6 A;  1E7I A;  1E78 A;  4Z69 A;  1FOU A;  1JNB A;  3MHS B;  1E7E A;  1HK3 A;  3V09 A;  1VZS A;  2I2Z A;  1VFI A;  2BXK A;  2OT3 A;  2ROH A;  3FWC C;  4TQ0 A;  3G9K D;  4Z9O A;  4ZBR A;  2I30 A;  1UOR A;  2CKX A;  4EMX A;  3LU7 A;  4N3Z A;  3WHQ A;  2AJE A;  4D7X A;  2EFD A;  2BXM A;  5GIO A;  2BXQ A;  4F5T A;  4ZBK A;  4HGM B;  5BPK A;  2QHB A;  2XW0 A;  2VUE A;  3ICX A;  3LU6 A;  2AGH B;  1HK2 A;  1GNJ A;  1E7C A;  2LQH A;  3GQX A;  4S1Y A;  3H3A A;  4MBE C;  1MIW A;  4G04 A;  3W1S A;  1MIY A;  4GG2 A;  2GUT A;  2LXS A;  2XVQ A;  5ID7 A;  4LA0 A;  3V08 A;  5FUO A;  4W4U B;  5IIU A;  1IJG A;  4N0F D;  4GDL B;  3NVI A;  1HK4 A;  2BXL A;  5IFO A;  2BXN A;  4K71 A;  5D7G A;  2KWF A;  3B9M A;  1E7G A;  3PLA A;  2XMO A;  2DBW A;  1E7F A;  1MA9 A;  4PO0 A;  4IW1 A;  1LOT A;  2VDB A;  3NMU A;  2EFH A;  2BX8 A;  2VUF A;  4ZCG A;  1KW2 A;  2DG5 A;  3M99 C;  4HGK A;  1E7B A;  1O9X A;  2DYO A;  3UIV A;  1J78 A;  5IIH A;  5IJ5 A;  2EFC A;  5ID9 A;  2BXP A;  4NAW B;  2Z8K A;  3KJL A;  1N5U A;  1BJ5 A;  1HA2 A;  1BM0 A;  4L8U A;  4BKE A;  1TF0 A;  5IJF A;  2DYM A;  4K2C A;  3WHS A;  3WHR A;  2LXT A;  1MUS A;  2LQI A;  2BXH A;  2XVV A;  4ZUX V;  1HK5 A;  3GQU A;  4F5S A;  2XVW A;  3NVK A;  4OTU A;  3TDL A;  2E0X A;  4I9O A;  3JQZ A;  5IJE A;  2Z8J A;  2EFE A;  4F5V A;  4FJC B;  5GHK A;  5DQF A;  2BXD A;  4E99 A;  4WA6 B;  4BY9 C;  3ECP A;  3SIU B;  2BXG A;  5GIN A;  1MUH A;  2Z8I A;  2OZB B;  3KIK A;  4L9K A;  2DBU A;  4ZC6 A;  4LUF A;  1E7H A;  2BXF A;  2JUH A;  3SIV B;  4N0U D;  1TXU A;  4DM0 A;  4LB2 A;  4IW2 A;  1AO6 A;  3GA9 L;  2QMC A; 
#chains in the Genus database with same CATH homology
 2XSI A;  4LB9 A;  4G01 A;  3FWB C;  3VQI A;  3LU8 A;  4FIP B;  1J7E A;  2XVU A;  5GIP A;  2XW1 A;  1KXP D;  1H9Z A;  1HK1 A;  2V36 A;  1BKE A;  3V03 A;  5B5T A;  3SQJ A;  2NNW A;  3CX9 A;  5HOZ A;  4M70 B;  3FNM A;  4G03 A;  5DBY A;  4FK5 B;  2BXI A;  3B9L A;  4LUH A;  4TQ1 A;  2BXE A;  2KBZ A;  3MHH B;  4GDX A;  2E0Y A;  4DHX B;  5IIX A;  2NQO A;  2BXB A;  2BXA A;  3A73 A;  1NT2 B;  1H5W A;  4F5U A;  2DBX A;  3JRY A;  1E7A A;  1MIV A;  2BXO A;  2LOQ A;  3NVM A;  4ZBQ A;  3A75 A;  4OTT A;  4OT2 A;  4JK4 A;  2BXC A;  1GNI A;  1LNS A;  4L9Q A;  4J2V A;  4OR0 A;  4C31 B;  2YDF A;  4GDK B;  3H37 A;  2QM6 A;  1E7I A;  1E78 A;  4Z69 A;  1FOU A;  1JNB A;  3MHS B;  1E7E A;  1HK3 A;  3V09 A;  1VZS A;  2I2Z A;  1VFI A;  2BXK A;  2OT3 A;  2ROH A;  3FWC C;  4TQ0 A;  3G9K D;  4Z9O A;  4ZBR A;  2I30 A;  1UOR A;  2CKX A;  4EMX A;  3LU7 A;  4N3Z A;  3WHQ A;  2AJE A;  2EFD A;  2BXM A;  5GIO A;  2BXQ A;  4F5T A;  4ZBK A;  4HGM B;  5BPK A;  2QHB A;  2XW0 A;  2VUE A;  3ICX A;  3LU6 A;  3GQX A;  1HK2 A;  1GNJ A;  1E7C A;  4S1Y A;  3H3A A;  4MBE C;  1MIW A;  4G04 A;  3W1S A;  1MIY A;  4GG2 A;  2XVQ A;  5ID7 A;  4LA0 A;  3V08 A;  5FUO A;  4W4U B;  5IIU A;  1IJG A;  4N0F D;  4GDL B;  3NVI A;  1HK4 A;  2BXL A;  5IFO A;  2BXN A;  4K71 A;  5D7G A;  3B9M A;  3PLA A;  1E7G A;  2XMO A;  2DBW A;  1E7F A;  1MA9 A;  4PO0 A;  4IW1 A;  1LOT A;  2VDB A;  3NMU A;  2EFH A;  2BX8 A;  2VUF A;  4ZCG A;  1KW2 A;  2DG5 A;  3M99 C;  4HGK A;  1E7B A;  1O9X A;  2DYO A;  3UIV A;  1J78 A;  5IIH A;  5IJ5 A;  2EFC A;  5ID9 A;  2BXP A;  4NAW B;  2Z8K A;  3KJL A;  1N5U A;  1BJ5 A;  1HA2 A;  1BM0 A;  4L8U A;  4BKE A;  1TF0 A;  5IJF A;  2DYM A;  4K2C A;  3WHS A;  3WHR A;  2XVV A;  2BXH A;  4ZUX V;  1HK5 A;  3GQU A;  4F5S A;  2XVW A;  3NVK A;  4OTU A;  3TDL A;  2E0X A;  5IJE A;  3JQZ A;  2Z8J A;  2EFE A;  4F5V A;  4FJC B;  5GHK A;  5DQF A;  2BXD A;  4E99 A;  4WA6 B;  4BY9 C;  3SIU B;  2BXG A;  5GIN A;  2Z8I A;  2OZB B;  3KIK A;  4L9K A;  2DBU A;  4ZC6 A;  4LUF A;  1E7H A;  2BXF A;  2JUH A;  3SIV B;  4N0U D;  1TXU A;  4LB2 A;  4IW2 A;  1AO6 A;  3GA9 L;  2QMC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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