4ZBKA

Crystal structure of human ggt1 in complex with ggstop inhibitor
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
342
structure length
342
Chain Sequence
DNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
pubmed doi rcsb
molecule keywords Gamma-glutamyltranspeptidase 1
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 109
structure length 342
sequence length 342
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2015-04-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbkA02
2QM6A 2NQOA 4Z9OA 2Z8JA 4ZBKA 2DG5A 4OTTA 3WHRA 2Z8IA 4OTUA 2E0YA 4GDXA 4ZC6A 4ZCGA 2QMCA 3FNMA 2V36A 3WHQA 3A75A 4GG2A 5BPKA 2DBUA 2E0XA 2DBWA 2Z8KA 5B5TA 3WHSA 2DBXA
chains in the Genus database with same CATH superfamily
4J2VA 2BX8A 2XVWA 5IFOA 5IJ5A 4TQ0A 5IIXA 1HK4A 1HK5A 2OT3A 1KW2A 4ZBKA 5IIUA 2XMOA 4L9KA 2DYMA 4LB9A 2BXNA 1J7EA 3W1SA 4M70B 4F5VA 2LQHA 5IJEA 3NVIA 2KBZA 3WHRA 2VDBA 2Z8IA 2BXGA 2BXIA 2E0YA 1MIVA 4TQ1A 4GDXA 4BKEA 1E7EA 2EFDA 5DBYA 1MM8A 3A73A 4K2CA 1E7GA 2VUEA 3JRYA 4LB2A 5DQFA 4F5UA 1O9XA 2VUFA 4W4UB 4DM0A 3GA9L 1H5WA 1GNJA 4HGKA 2JUHA 3ICXA 4G03A 2LOQA 5HOZA 1MA9A 2XVVA 3MHSB 4OR0A 2E0XA 5B5TA 2Z8KA 3NVMA 2XVQA 2YDFA 3WHSA 3GQUA 1BM0A 4D7XA 3SIVB 1IJGA 4WA6B 4S1YA 3G9KD 1FOUA 3LU8A 4BY9C 4Z9OA 3V09A 2QHBA 4L9QA 1NT2B 4LUFA 4F5TA 1BKEA 2I30A 2BXAA 3PLAA 4DHXB 4GDLB 4FK5B 4Z69A 4N0FD 4ZC6A 4ZCGA 4OT2A 1HA2A 2NNWA 2BXBA 2BXDA 3FNMA 2BXMA 5GIPA 5ID9A 2BXHA 3JQZA 3WHQA 1JNBA 4ZUXV 4GG2A 4HGMB 1MIYA 4E99A 5FUOA 1J78A 3B9LA 1VFIA 2DBWA 2EFHA 3H3AA 2XW0A 4L8UA 2QM6A 3NMUA 1LNSA 1SB0A 3M99C 4N0UD 1E7BA 4IW1A 1MIWA 1VZSA 4LA0A 4NAWB 3GQXA 2BXCA 2LXTA 5GHKA 1UORA 2GUTA 5IIHA 3SQJA 3CX9A 2DG5A 1LOTA 3UIVA 2XVUA 5IJFA 4N3ZA 4FJCB 3KIKA 1E7CA 1TXUA 4G01A 4PO0A 2BXOA 2AGHB 2LQIA 3MHHB 1N5UA 5GIOA 2CKXA 4FIPB 4LUHA 1E7FA 3FWBC 1AO6A 2DBUA 1E78A 4F5SA 2XW1A 1HK1A 2DBXA 1KDXA 1E7AA 2KWFA 1H9ZA 2NQOA 2ROHA 4K71A 1E7HA 2EFCA 4I9OA 4JK4A 2BXLA 2LXSA 2Z8JA 1KXPD 2BXPA 3SIUB 1E7IA 3FWCC 3LU6A 1HK3A 2DYOA 3BPJA 4EMXA 1TF0A 2XSIA 4IW2A 4OTTA 2OZBB 4OTUA 2I2ZA 4G04A 4C31B 2K0NA 3TDLA 2BXEA 4GDKB 2BXQA 3H37A 5ID7A 1MUHA 2QMCA 2BXKA 2V36A 3KJLA 3ECPA 3A75A 5D7GA 2AJEA 5BPKA 3NVKA 3V03A 1BJ5A 2EFEA 3B9MA 1GNIA 3V08A 4MBEC 4ZBRA 3LU7A 1HK2A 4ZBQA 3VQIA 1MUSA 2BXFA 5GINA
chains in the Genus database with same CATH topology
4J2VA 2BX8A 2XVWA 5IFOA 5IJ5A 4TQ0A 5IIXA 1HK4A 1HK5A 2OT3A 1KW2A 4ZBKA 5IIUA 2XMOA 4L9KA 2DYMA 4LB9A 2BXNA 1J7EA 3W1SA 4M70B 4F5VA 3NVIA 5IJEA 2KBZA 3WHRA 2VDBA 2Z8IA 2BXGA 2BXIA 2E0YA 1MIVA 4TQ1A 4GDXA 4BKEA 1E7EA 2EFDA 5DBYA 3A73A 4K2CA 1E7GA 2VUEA 3JRYA 4LB2A 5DQFA 4F5UA 1O9XA 2VUFA 4W4UB 3GA9L 1H5WA 1GNJA 4HGKA 2JUHA 3ICXA 4G03A 2LOQA 5HOZA 1MA9A 2XVVA 3MHSB 4OR0A 2E0XA 5B5TA 2Z8KA 3NVMA 2XVQA 2YDFA 3WHSA 3GQUA 1BM0A 3SIVB 1IJGA 4WA6B 4S1YA 3G9KD 1FOUA 3LU8A 4BY9C 4Z9OA 3V09A 2QHBA 4L9QA 1NT2B 4LUFA 4F5TA 1BKEA 2I30A 2BXAA 3PLAA 4DHXB 4GDLB 4FK5B 4Z69A 4N0FD 4ZC6A 4ZCGA 4OT2A 1HA2A 2NNWA 2BXBA 2BXDA 3FNMA 2BXMA 5GIPA 5ID9A 2BXHA 3JQZA 3WHQA 1JNBA 4ZUXV 4GG2A 4HGMB 1MIYA 4E99A 5FUOA 1J78A 3B9LA 1VFIA 2DBWA 2EFHA 3H3AA 2XW0A 4L8UA 2QM6A 3NMUA 1LNSA 3M99C 4N0UD 1E7BA 4IW1A 1MIWA 1VZSA 4LA0A 4NAWB 3GQXA 2BXCA 5GHKA 1UORA 5IIHA 3SQJA 3CX9A 2DG5A 1LOTA 3UIVA 2XVUA 5IJFA 4N3ZA 4FJCB 3KIKA 1E7CA 1TXUA 4G01A 4PO0A 2BXOA 3MHHB 1N5UA 5GIOA 2CKXA 4FIPB 4LUHA 1E7FA 3FWBC 1AO6A 2DBUA 1E78A 4F5SA 2XW1A 1HK1A 2DBXA 1E7AA 1H9ZA 2NQOA 2ROHA 4K71A 1E7HA 2EFCA 4JK4A 2BXLA 2Z8JA 1KXPD 2BXPA 3SIUB 1E7IA 3FWCC 3LU6A 1HK3A 2DYOA 4EMXA 1TF0A 2XSIA 4IW2A 4OTTA 2OZBB 4OTUA 2I2ZA 4G04A 4C31B 3TDLA 2BXEA 4GDKB 2BXQA 3H37A 5ID7A 2QMCA 2BXKA 2V36A 3KJLA 3A75A 5D7GA 2AJEA 5BPKA 3NVKA 3V03A 1BJ5A 2EFEA 3B9MA 1GNIA 3V08A 4MBEC 4ZBRA 3LU7A 1HK2A 4ZBQA 3VQIA 2BXFA 5GINA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QM6 A;  2NQO A;  4Z9O A;  2Z8J A;  4ZBK A;  2DG5 A;  4OTT A;  3WHR A;  2Z8I A;  4OTU A;  2E0Y A;  4GDX A;  4ZC6 A;  4ZCG A;  2QMC A;  3FNM A;  2V36 A;  3WHQ A;  3A75 A;  4GG2 A;  5BPK A;  2DBU A;  2E0X A;  2DBW A;  2Z8K A;  5B5T A;  3WHS A;  2DBX A; 
#chains in the Genus database with same CATH topology
 4J2V A;  2BX8 A;  2XVW A;  5IFO A;  5IJ5 A;  4TQ0 A;  5IIX A;  1HK4 A;  1HK5 A;  2OT3 A;  1KW2 A;  4ZBK A;  5IIU A;  2XMO A;  4L9K A;  2DYM A;  4LB9 A;  2BXN A;  1J7E A;  3W1S A;  4M70 B;  4F5V A;  2LQH A;  5IJE A;  3NVI A;  2KBZ A;  3WHR A;  2VDB A;  2Z8I A;  2BXG A;  2BXI A;  2E0Y A;  1MIV A;  4TQ1 A;  4GDX A;  4BKE A;  1E7E A;  2EFD A;  5DBY A;  1MM8 A;  3A73 A;  4K2C A;  1E7G A;  2VUE A;  3JRY A;  4LB2 A;  5DQF A;  4F5U A;  1O9X A;  2VUF A;  4W4U B;  4DM0 A;  3GA9 L;  1H5W A;  1GNJ A;  4HGK A;  2JUH A;  3ICX A;  4G03 A;  2LOQ A;  5HOZ A;  1MA9 A;  2XVV A;  3MHS B;  4OR0 A;  2E0X A;  5B5T A;  2Z8K A;  3NVM A;  2XVQ A;  2YDF A;  3WHS A;  3GQU A;  1BM0 A;  4D7X A;  3SIV B;  1IJG A;  4WA6 B;  4S1Y A;  3G9K D;  1FOU A;  3LU8 A;  4BY9 C;  4Z9O A;  3V09 A;  2QHB A;  4L9Q A;  1NT2 B;  4LUF A;  4F5T A;  1BKE A;  2I30 A;  2BXA A;  3PLA A;  4DHX B;  4GDL B;  4FK5 B;  4Z69 A;  4N0F D;  4ZC6 A;  4ZCG A;  4OT2 A;  1HA2 A;  2NNW A;  2BXB A;  2BXD A;  3FNM A;  2BXM A;  5GIP A;  5ID9 A;  2BXH A;  3JQZ A;  3WHQ A;  1JNB A;  4ZUX V;  4GG2 A;  4HGM B;  1MIY A;  4E99 A;  5FUO A;  1J78 A;  3B9L A;  1VFI A;  2DBW A;  2EFH A;  3H3A A;  2XW0 A;  4L8U A;  2QM6 A;  3NMU A;  1LNS A;  1SB0 A;  3M99 C;  4N0U D;  1E7B A;  4IW1 A;  1MIW A;  1VZS A;  4LA0 A;  4NAW B;  3GQX A;  2BXC A;  2LXT A;  5GHK A;  1UOR A;  2GUT A;  5IIH A;  3SQJ A;  3CX9 A;  2DG5 A;  1LOT A;  3UIV A;  2XVU A;  5IJF A;  4N3Z A;  4FJC B;  3KIK A;  1E7C A;  1TXU A;  4G01 A;  4PO0 A;  2BXO A;  2AGH B;  2LQI A;  3MHH B;  1N5U A;  5GIO A;  2CKX A;  4FIP B;  4LUH A;  1E7F A;  3FWB C;  1AO6 A;  2DBU A;  1E78 A;  4F5S A;  2XW1 A;  1HK1 A;  2DBX A;  1KDX A;  1E7A A;  2KWF A;  1H9Z A;  2NQO A;  2ROH A;  4K71 A;  1E7H A;  2EFC A;  4I9O A;  4JK4 A;  2BXL A;  2LXS A;  2Z8J A;  1KXP D;  2BXP A;  3SIU B;  1E7I A;  3FWC C;  3LU6 A;  1HK3 A;  2DYO A;  3BPJ A;  4EMX A;  1TF0 A;  2XSI A;  4IW2 A;  4OTT A;  2OZB B;  4OTU A;  2I2Z A;  4G04 A;  4C31 B;  2K0N A;  3TDL A;  2BXE A;  4GDK B;  2BXQ A;  3H37 A;  5ID7 A;  1MUH A;  2QMC A;  2BXK A;  2V36 A;  3KJL A;  3ECP A;  3A75 A;  5D7G A;  2AJE A;  5BPK A;  3NVK A;  3V03 A;  1BJ5 A;  2EFE A;  3B9M A;  1GNI A;  3V08 A;  4MBE C;  4ZBR A;  3LU7 A;  1HK2 A;  4ZBQ A;  3VQI A;  1MUS A;  2BXF A;  5GIN A; 
#chains in the Genus database with same CATH homology
 4J2V A;  2BX8 A;  2XVW A;  5IFO A;  5IJ5 A;  4TQ0 A;  5IIX A;  1HK4 A;  1HK5 A;  2OT3 A;  1KW2 A;  4ZBK A;  5IIU A;  2XMO A;  4L9K A;  2DYM A;  4LB9 A;  2BXN A;  1J7E A;  3W1S A;  4M70 B;  4F5V A;  3NVI A;  5IJE A;  2KBZ A;  3WHR A;  2VDB A;  2Z8I A;  2BXG A;  2BXI A;  2E0Y A;  1MIV A;  4TQ1 A;  4GDX A;  4BKE A;  1E7E A;  2EFD A;  5DBY A;  3A73 A;  4K2C A;  1E7G A;  2VUE A;  3JRY A;  4LB2 A;  5DQF A;  4F5U A;  1O9X A;  2VUF A;  4W4U B;  3GA9 L;  1H5W A;  1GNJ A;  4HGK A;  2JUH A;  3ICX A;  4G03 A;  2LOQ A;  5HOZ A;  1MA9 A;  2XVV A;  3MHS B;  4OR0 A;  2E0X A;  5B5T A;  2Z8K A;  3NVM A;  2XVQ A;  2YDF A;  3WHS A;  3GQU A;  1BM0 A;  3SIV B;  1IJG A;  4WA6 B;  4S1Y A;  3G9K D;  1FOU A;  3LU8 A;  4BY9 C;  4Z9O A;  3V09 A;  2QHB A;  4L9Q A;  1NT2 B;  4LUF A;  4F5T A;  1BKE A;  2I30 A;  2BXA A;  3PLA A;  4DHX B;  4GDL B;  4FK5 B;  4Z69 A;  4N0F D;  4ZC6 A;  4ZCG A;  4OT2 A;  1HA2 A;  2NNW A;  2BXB A;  2BXD A;  3FNM A;  2BXM A;  5GIP A;  5ID9 A;  2BXH A;  3JQZ A;  3WHQ A;  1JNB A;  4ZUX V;  4GG2 A;  4HGM B;  1MIY A;  4E99 A;  5FUO A;  1J78 A;  3B9L A;  1VFI A;  2DBW A;  2EFH A;  3H3A A;  2XW0 A;  4L8U A;  2QM6 A;  3NMU A;  1LNS A;  3M99 C;  4N0U D;  1E7B A;  4IW1 A;  1MIW A;  1VZS A;  4LA0 A;  4NAW B;  3GQX A;  2BXC A;  5GHK A;  1UOR A;  5IIH A;  3SQJ A;  3CX9 A;  2DG5 A;  1LOT A;  3UIV A;  2XVU A;  5IJF A;  4N3Z A;  4FJC B;  3KIK A;  1E7C A;  1TXU A;  4G01 A;  4PO0 A;  2BXO A;  3MHH B;  1N5U A;  5GIO A;  2CKX A;  4FIP B;  4LUH A;  1E7F A;  3FWB C;  1AO6 A;  2DBU A;  1E78 A;  4F5S A;  2XW1 A;  1HK1 A;  2DBX A;  1E7A A;  1H9Z A;  2NQO A;  2ROH A;  4K71 A;  1E7H A;  2EFC A;  4JK4 A;  2BXL A;  2Z8J A;  1KXP D;  2BXP A;  3SIU B;  1E7I A;  3FWC C;  3LU6 A;  1HK3 A;  2DYO A;  4EMX A;  1TF0 A;  2XSI A;  4IW2 A;  4OTT A;  2OZB B;  4OTU A;  2I2Z A;  4G04 A;  4C31 B;  3TDL A;  2BXE A;  4GDK B;  2BXQ A;  3H37 A;  5ID7 A;  2QMC A;  2BXK A;  2V36 A;  3KJL A;  3A75 A;  5D7G A;  2AJE A;  5BPK A;  3NVK A;  3V03 A;  1BJ5 A;  2EFE A;  3B9M A;  1GNI A;  3V08 A;  4MBE C;  4ZBR A;  3LU7 A;  1HK2 A;  4ZBQ A;  3VQI A;  2BXF A;  5GIN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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