4ZBQA

Crystal structure of equine serum albumin in complex with diclofenac
Total Genus 236
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
236
sequence length
580
structure length
580
Chain Sequence
KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKAGCLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYATVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into the Competitive Binding of Diclofenac and Naproxen by Equine Serum Albumin.
pubmed doi rcsb
molecule keywords Serum albumin
molecule tags Transport protein
total genus 236
structure length 580
sequence length 580
ec nomenclature
pdb deposition date 2015-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbqA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbqA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbqA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbqA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbqA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbqA05
2XVVA 3CX9A 5IJ5A 1GNJA 1HA2A 2BXFA 2BXKA 2XW0A 1E7EA 4N0UD 2BXDA 1E7HA 1E7FA 5IJFA 4G03A 1BJ5A 1KXPD 1HK4A 3UIVA 5ID7A 4OT2A 5HOZA 3JQZA 2BXCA 1E7BA 1O9XA 3A73A 2XVUA 2XSIA 2BXIA 3LU8A 4LA0A 4F5SA 3V09A 3B9MA 4BKEA 4L9KA 4L8UA 1TF0A 3JRYA 4IW1A 1KW2A 1N5UA 1UORA 2BXEA 2I2ZA 5DQFA 4F5TA 4Z69A 4L9QA 4G04A 3V08A 2BXLA 4IW2A 1E7GA 4HGMB 1LOTA 2BXAA 3SQJA 2BXMA 4N0FD 2BXGA 1E7AA 4LUHA 2BXBA 3TDLA 5IJEA 2BXOA 1BM0A 2XW1A 4LUFA 5ID9A 3V03A 1HK5A 1BKEA 1E78A 1HK3A 2VUFA 4ZBRA 2I30A 4HGKA 1HK1A 5IFOA 4S1YA 2XVQA 4OR0A 1HK2A 5IIXA 3B9LA 3LU6A 1E7CA 4K71A 2XVWA 1J7EA 1GNIA 5FUOA 3LU7A 1E7IA 2BXNA 2YDFA 2BX8A 5GHKA 5DBYA 4K2CA 1H9ZA 1MA9A 4PO0A 4E99A 4F5VA 4LB2A 4F5UA 4LB9A 2BXHA 2BXPA 4ZBQA 1AO6A 5IIUA 4EMXA 2VDBA 4J2VA 2VUEA 4JK4A 5IIHA 2BXQA 1J78A
chains in the Genus database with same CATH superfamily
5B5TA 2XVVA 3CX9A 5IJ5A 1GNJA 1HA2A 2LQHA 2BXFA 2DBUA 4W4UB 2GUTA 4G01A 3WHRA 2Z8IA 2BXKA 2XW0A 3PLAA 1LNSA 5GIOA 1E7EA 3MHSB 4N0UD 2BXDA 1E7HA 3VQIA 2JUHA 1E7FA 2ROHA 5IJFA 2EFEA 2AGHB 4ZC6A 3ICXA 2EFCA 4G03A 1BJ5A 1KXPD 3WHSA 5GINA 2LXTA 1HK4A 3KIKA 3UIVA 5ID7A 3H37A 4OT2A 5HOZA 4OTTA 3JQZA 2BXCA 1E7BA 1O9XA 3A73A 3FWBC 2XVUA 2XSIA 2BXIA 3LU8A 4GDXA 2QMCA 3GQXA 4LA0A 4GG2A 2DBWA 2LXSA 4F5SA 2E0XA 3V09A 4N3ZA 3B9MA 4BKEA 4L9KA 4L8UA 1TF0A 2Z8JA 3JRYA 4IW1A 1KW2A 1N5UA 1UORA 2BXEA 2I2ZA 3FNMA 5DQFA 4F5TA 3G9KD 1FOUA 3FWCC 3KJLA 4Z69A 4L9QA 4ZBKA 4G04A 4WA6B 3V08A 2BXLA 4TQ0A 2KBZA 4IW2A 1E7GA 4HGMB 1LOTA 4GDKB 4M70B 2BXAA 3SQJA 2BXMA 4N0FD 3A75A 2BXGA 4FJCB 4DM0A 2DBXA 1E7AA 3SIUB 4LUHA 3WHQA 2BXBA 3TDLA 5IJEA 2BXOA 1BM0A 2NNWA 4TQ1A 2XW1A 4LUFA 4BY9C 2QM6A 5ID9A 2K0NA 3GQUA 3V03A 1HK5A 1BKEA 3SIVB 1SB0A 1MUSA 1JNBA 1E78A 4GDLB 4ZCGA 1HK3A 2VUFA 1VZSA 2DYOA 4OTUA 4ZBRA 2KWFA 3NMUA 2I30A 2Z8KA 4HGKA 4FK5B 1HK1A 5IFOA 5BPKA 1NT2B 1MUHA 2DG5A 4S1YA 2XVQA 4OR0A 3BPJA 1VFIA 1HK2A 3NVMA 5D7GA 5IIXA 3NVKA 4FIPB 2QHBA 5GIPA 1H5WA 3B9LA 3LU6A 2OZBB 2V36A 3GA9L 1E7CA 2AJEA 1KDXA 3M99C 3MHHB 4K71A 2XVWA 2DYMA 1J7EA 1GNIA 2NQOA 1TXUA 5FUOA 3LU7A 1E7IA 3NVIA 4NAWB 2BXNA 2YDFA 4DHXB 2BX8A 5GHKA 4I9OA 5DBYA 4K2CA 4C31B 1MIVA 4MBEC 2EFHA 2OT3A 2XMOA 1H9ZA 1MA9A 4PO0A 1MIWA 4E99A 2CKXA 2E0YA 4F5VA 4LB2A 4F5UA 4LB9A 2BXHA 4ZUXV 2BXPA 4ZBQA 3W1SA 1AO6A 3H3AA 4D7XA 5IIUA 4EMXA 3ECPA 2VDBA 4J2VA 4Z9OA 2LQIA 2EFDA 2LOQA 1MM8A 1MIYA 2VUEA 4JK4A 5IIHA 1IJGA 2BXQA 1J78A
chains in the Genus database with same CATH topology
5B5TA 2XVVA 3CX9A 5IJ5A 1GNJA 1HA2A 2BXFA 2DBUA 4W4UB 4G01A 3WHRA 2Z8IA 2BXKA 2XW0A 3PLAA 1LNSA 5GIOA 1E7EA 3MHSB 4N0UD 2BXDA 1E7HA 3VQIA 2JUHA 1E7FA 2ROHA 5IJFA 2EFEA 4ZC6A 3ICXA 2EFCA 4G03A 1BJ5A 1KXPD 3WHSA 5GINA 1HK4A 3KIKA 3UIVA 5ID7A 3H37A 4OT2A 5HOZA 4OTTA 3JQZA 2BXCA 1E7BA 1O9XA 3A73A 3FWBC 2XVUA 2XSIA 2BXIA 3LU8A 4GDXA 2QMCA 3GQXA 4LA0A 4GG2A 2DBWA 4F5SA 2E0XA 3V09A 4N3ZA 3B9MA 4BKEA 4L9KA 4L8UA 1TF0A 2Z8JA 3JRYA 4IW1A 1KW2A 1N5UA 1UORA 2BXEA 2I2ZA 3FNMA 5DQFA 4F5TA 3G9KD 1FOUA 3FWCC 3KJLA 4Z69A 4L9QA 4ZBKA 4G04A 4WA6B 3V08A 2BXLA 4TQ0A 2KBZA 4IW2A 1E7GA 4HGMB 1LOTA 4GDKB 4M70B 2BXAA 3SQJA 2BXMA 4N0FD 3A75A 2BXGA 4FJCB 2DBXA 1E7AA 3SIUB 4LUHA 3WHQA 2BXBA 3TDLA 5IJEA 2BXOA 1BM0A 2NNWA 4TQ1A 2XW1A 4LUFA 4BY9C 2QM6A 5ID9A 3GQUA 3V03A 1HK5A 1BKEA 3SIVB 1JNBA 1E78A 4GDLB 4ZCGA 1HK3A 2VUFA 1VZSA 2DYOA 4OTUA 4ZBRA 3NMUA 2I30A 2Z8KA 4HGKA 4FK5B 1HK1A 5IFOA 5BPKA 1NT2B 2DG5A 4S1YA 2XVQA 4OR0A 1VFIA 1HK2A 3NVMA 5D7GA 5IIXA 3NVKA 4FIPB 2QHBA 5GIPA 1H5WA 3B9LA 3LU6A 2OZBB 2V36A 3GA9L 1E7CA 2AJEA 3M99C 3MHHB 4K71A 2XVWA 2DYMA 1J7EA 1GNIA 2NQOA 1TXUA 5FUOA 3LU7A 1E7IA 3NVIA 4NAWB 2BXNA 2YDFA 4DHXB 2BX8A 5GHKA 5DBYA 4K2CA 4C31B 1MIVA 4MBEC 2EFHA 2OT3A 2XMOA 1H9ZA 1MA9A 4PO0A 1MIWA 4E99A 2CKXA 2E0YA 4F5VA 4LB2A 4F5UA 4LB9A 2BXHA 4ZUXV 2BXPA 4ZBQA 3W1SA 1AO6A 3H3AA 5IIUA 4EMXA 2VDBA 4J2VA 4Z9OA 2EFDA 2LOQA 1MIYA 2VUEA 4JK4A 5IIHA 1IJGA 2BXQA 1J78A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XVV A;  3CX9 A;  5IJ5 A;  1GNJ A;  1HA2 A;  2BXF A;  2BXK A;  2XW0 A;  1E7E A;  4N0U D;  2BXD A;  1E7H A;  1E7F A;  5IJF A;  4G03 A;  1BJ5 A;  1KXP D;  1HK4 A;  3UIV A;  5ID7 A;  4OT2 A;  5HOZ A;  3JQZ A;  2BXC A;  1E7B A;  1O9X A;  3A73 A;  2XVU A;  2XSI A;  2BXI A;  3LU8 A;  4LA0 A;  4F5S A;  3V09 A;  3B9M A;  4BKE A;  4L9K A;  4L8U A;  1TF0 A;  3JRY A;  4IW1 A;  1KW2 A;  1N5U A;  1UOR A;  2BXE A;  2I2Z A;  5DQF A;  4F5T A;  4Z69 A;  4L9Q A;  4G04 A;  3V08 A;  2BXL A;  4IW2 A;  1E7G A;  4HGM B;  1LOT A;  2BXA A;  3SQJ A;  2BXM A;  4N0F D;  2BXG A;  1E7A A;  4LUH A;  2BXB A;  3TDL A;  5IJE A;  2BXO A;  1BM0 A;  2XW1 A;  4LUF A;  5ID9 A;  3V03 A;  1HK5 A;  1BKE A;  1E78 A;  1HK3 A;  2VUF A;  4ZBR A;  2I30 A;  4HGK A;  1HK1 A;  5IFO A;  4S1Y A;  2XVQ A;  4OR0 A;  1HK2 A;  5IIX A;  3B9L A;  3LU6 A;  1E7C A;  4K71 A;  2XVW A;  1J7E A;  1GNI A;  5FUO A;  3LU7 A;  1E7I A;  2BXN A;  2YDF A;  2BX8 A;  5GHK A;  5DBY A;  4K2C A;  1H9Z A;  1MA9 A;  4PO0 A;  4E99 A;  4F5V A;  4LB2 A;  4F5U A;  4LB9 A;  2BXH A;  2BXP A;  4ZBQ A;  1AO6 A;  5IIU A;  4EMX A;  2VDB A;  4J2V A;  2VUE A;  4JK4 A;  5IIH A;  2BXQ A;  1J78 A; 
#chains in the Genus database with same CATH topology
 5B5T A;  2XVV A;  3CX9 A;  5IJ5 A;  1GNJ A;  1HA2 A;  2LQH A;  2BXF A;  2DBU A;  4W4U B;  2GUT A;  4G01 A;  3WHR A;  2Z8I A;  2BXK A;  2XW0 A;  3PLA A;  1LNS A;  5GIO A;  1E7E A;  3MHS B;  4N0U D;  2BXD A;  1E7H A;  3VQI A;  2JUH A;  1E7F A;  2ROH A;  5IJF A;  2EFE A;  2AGH B;  4ZC6 A;  3ICX A;  2EFC A;  4G03 A;  1BJ5 A;  1KXP D;  3WHS A;  5GIN A;  2LXT A;  1HK4 A;  3KIK A;  3UIV A;  5ID7 A;  3H37 A;  4OT2 A;  5HOZ A;  4OTT A;  3JQZ A;  2BXC A;  1E7B A;  1O9X A;  3A73 A;  3FWB C;  2XVU A;  2XSI A;  2BXI A;  3LU8 A;  4GDX A;  2QMC A;  3GQX A;  4LA0 A;  4GG2 A;  2DBW A;  2LXS A;  4F5S A;  2E0X A;  3V09 A;  4N3Z A;  3B9M A;  4BKE A;  4L9K A;  4L8U A;  1TF0 A;  2Z8J A;  3JRY A;  4IW1 A;  1KW2 A;  1N5U A;  1UOR A;  2BXE A;  2I2Z A;  3FNM A;  5DQF A;  4F5T A;  3G9K D;  1FOU A;  3FWC C;  3KJL A;  4Z69 A;  4L9Q A;  4ZBK A;  4G04 A;  4WA6 B;  3V08 A;  2BXL A;  4TQ0 A;  2KBZ A;  4IW2 A;  1E7G A;  4HGM B;  1LOT A;  4GDK B;  4M70 B;  2BXA A;  3SQJ A;  2BXM A;  4N0F D;  3A75 A;  2BXG A;  4FJC B;  4DM0 A;  2DBX A;  1E7A A;  3SIU B;  4LUH A;  3WHQ A;  2BXB A;  3TDL A;  5IJE A;  2BXO A;  1BM0 A;  2NNW A;  4TQ1 A;  2XW1 A;  4LUF A;  4BY9 C;  2QM6 A;  5ID9 A;  2K0N A;  3GQU A;  3V03 A;  1HK5 A;  1BKE A;  3SIV B;  1SB0 A;  1MUS A;  1JNB A;  1E78 A;  4GDL B;  4ZCG A;  1HK3 A;  2VUF A;  1VZS A;  2DYO A;  4OTU A;  4ZBR A;  2KWF A;  3NMU A;  2I30 A;  2Z8K A;  4HGK A;  4FK5 B;  1HK1 A;  5IFO A;  5BPK A;  1NT2 B;  1MUH A;  2DG5 A;  4S1Y A;  2XVQ A;  4OR0 A;  3BPJ A;  1VFI A;  1HK2 A;  3NVM A;  5D7G A;  5IIX A;  3NVK A;  4FIP B;  2QHB A;  5GIP A;  1H5W A;  3B9L A;  3LU6 A;  2OZB B;  2V36 A;  3GA9 L;  1E7C A;  2AJE A;  1KDX A;  3M99 C;  3MHH B;  4K71 A;  2XVW A;  2DYM A;  1J7E A;  1GNI A;  2NQO A;  1TXU A;  5FUO A;  3LU7 A;  1E7I A;  3NVI A;  4NAW B;  2BXN A;  2YDF A;  4DHX B;  2BX8 A;  5GHK A;  4I9O A;  5DBY A;  4K2C A;  4C31 B;  1MIV A;  4MBE C;  2EFH A;  2OT3 A;  2XMO A;  1H9Z A;  1MA9 A;  4PO0 A;  1MIW A;  4E99 A;  2CKX A;  2E0Y A;  4F5V A;  4LB2 A;  4F5U A;  4LB9 A;  2BXH A;  4ZUX V;  2BXP A;  4ZBQ A;  3W1S A;  1AO6 A;  3H3A A;  4D7X A;  5IIU A;  4EMX A;  3ECP A;  2VDB A;  4J2V A;  4Z9O A;  2LQI A;  2EFD A;  2LOQ A;  1MM8 A;  1MIY A;  2VUE A;  4JK4 A;  5IIH A;  1IJG A;  2BXQ A;  1J78 A; 
#chains in the Genus database with same CATH homology
 5B5T A;  2XVV A;  3CX9 A;  5IJ5 A;  1GNJ A;  1HA2 A;  2BXF A;  2DBU A;  4W4U B;  4G01 A;  3WHR A;  2Z8I A;  2BXK A;  2XW0 A;  3PLA A;  1LNS A;  5GIO A;  1E7E A;  3MHS B;  4N0U D;  2BXD A;  1E7H A;  3VQI A;  2JUH A;  1E7F A;  2ROH A;  5IJF A;  2EFE A;  4ZC6 A;  3ICX A;  2EFC A;  4G03 A;  1BJ5 A;  1KXP D;  3WHS A;  5GIN A;  1HK4 A;  3KIK A;  3UIV A;  5ID7 A;  3H37 A;  4OT2 A;  5HOZ A;  4OTT A;  3JQZ A;  2BXC A;  1E7B A;  1O9X A;  3A73 A;  3FWB C;  2XVU A;  2XSI A;  2BXI A;  3LU8 A;  4GDX A;  2QMC A;  3GQX A;  4LA0 A;  4GG2 A;  2DBW A;  4F5S A;  2E0X A;  3V09 A;  4N3Z A;  3B9M A;  4BKE A;  4L9K A;  4L8U A;  1TF0 A;  2Z8J A;  3JRY A;  4IW1 A;  1KW2 A;  1N5U A;  1UOR A;  2BXE A;  2I2Z A;  3FNM A;  5DQF A;  4F5T A;  3G9K D;  1FOU A;  3FWC C;  3KJL A;  4Z69 A;  4L9Q A;  4ZBK A;  4G04 A;  4WA6 B;  3V08 A;  2BXL A;  4TQ0 A;  2KBZ A;  4IW2 A;  1E7G A;  4HGM B;  1LOT A;  4GDK B;  4M70 B;  2BXA A;  3SQJ A;  2BXM A;  4N0F D;  3A75 A;  2BXG A;  4FJC B;  2DBX A;  1E7A A;  3SIU B;  4LUH A;  3WHQ A;  2BXB A;  3TDL A;  5IJE A;  2BXO A;  1BM0 A;  2NNW A;  4TQ1 A;  2XW1 A;  4LUF A;  4BY9 C;  2QM6 A;  5ID9 A;  3GQU A;  3V03 A;  1HK5 A;  1BKE A;  3SIV B;  1JNB A;  1E78 A;  4GDL B;  4ZCG A;  1HK3 A;  2VUF A;  1VZS A;  2DYO A;  4OTU A;  4ZBR A;  3NMU A;  2I30 A;  2Z8K A;  4HGK A;  4FK5 B;  1HK1 A;  5IFO A;  5BPK A;  1NT2 B;  2DG5 A;  4S1Y A;  2XVQ A;  4OR0 A;  1VFI A;  1HK2 A;  3NVM A;  5D7G A;  5IIX A;  3NVK A;  4FIP B;  2QHB A;  5GIP A;  1H5W A;  3B9L A;  3LU6 A;  2OZB B;  2V36 A;  3GA9 L;  1E7C A;  2AJE A;  3M99 C;  3MHH B;  4K71 A;  2XVW A;  2DYM A;  1J7E A;  1GNI A;  2NQO A;  1TXU A;  5FUO A;  3LU7 A;  1E7I A;  3NVI A;  4NAW B;  2BXN A;  2YDF A;  4DHX B;  2BX8 A;  5GHK A;  5DBY A;  4K2C A;  4C31 B;  1MIV A;  4MBE C;  2EFH A;  2OT3 A;  2XMO A;  1H9Z A;  1MA9 A;  4PO0 A;  1MIW A;  4E99 A;  2CKX A;  2E0Y A;  4F5V A;  4LB2 A;  4F5U A;  4LB9 A;  2BXH A;  4ZUX V;  2BXP A;  4ZBQ A;  3W1S A;  1AO6 A;  3H3A A;  5IIU A;  4EMX A;  2VDB A;  4J2V A;  4Z9O A;  2EFD A;  2LOQ A;  1MIY A;  2VUE A;  4JK4 A;  5IIH A;  1IJG A;  2BXQ A;  1J78 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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