The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
103
|
sequence length |
349
|
structure length |
349
|
Chain Sequence |
DVFHPVRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYE
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Phosphonate-based irreversible inhibitors of human gamma-glutamyl transpeptidase (GGT). GGsTop is a non-toxic and highly selective inhibitor with critical electrostatic interaction with an active-site residue Lys562 for enhanced inhibitory activity
pubmed doi rcsb |
| molecule keywords |
Gamma-glutamyltranspeptidase large chain
|
| molecule tags |
Hydrolase/hydrolase inhibitor
|
| source organism |
Escherichia coli (strain k12)
|
| total genus |
103
|
| structure length |
349
|
| sequence length |
349
|
| chains with identical sequence |
C
|
| ec nomenclature |
ec
2.3.2.2: Gamma-glutamyltransferase. |
| pdb deposition date | 2016-05-18 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Serum Albumin; Chain A, Domain 1 | Serum Albumin; Chain A, Domain 1 |
#chains in the Genus database with same CATH superfamily 4OTU A; 4ZC6 A; 2QM6 A; 2E0X A; 2E0Y A; 4ZCG A; 5BPK A; 2DBW A; 4OTT A; 2QMC A; 2DG5 A; 2Z8K A; 4ZBK A; 2NQO A; 4Z9O A; 2DBX A; 3WHR A; 3FNM A; 2DBU A; 3A75 A; 2V36 A; 4GDX A; 4GG2 A; 2Z8I A; 3WHS A; 5B5T A; 3WHQ A; 2Z8J A; #chains in the Genus database with same CATH topology 2BXP A; 4ZC6 A; 1E7C A; 4N3Z A; 2XVW A; 3ICX A; 2BXB A; 4L9Q A; 2XW0 A; 3V09 A; 4W4U B; 1KW2 A; 1E7B A; 1MUS A; 4BY9 C; 1E78 A; 1KXP D; 2QMC A; 3NVK A; 5FUO A; 4K2C A; 2Z8K A; 3JQZ A; 5GIN A; 1HA2 A; 4HGK A; 2NNW A; 2LOQ A; 1HK4 A; 4L9K A; 2NQO A; 4BKE A; 1MA9 A; 2LXT A; 1BM0 A; 3LU6 A; 1SB0 A; 3B9M A; 4FJC B; 4JK4 A; 4G04 A; 4MBE C; 2KWF A; 4N0U D; 3PLA A; 2BXM A; 2XMO A; 2V36 A; 2BXF A; 3GA9 L; 4GDL B; 5IIX A; 2BXC A; 1HK2 A; 2Z8I A; 4ZBR A; 4ZUX V; 3JRY A; 3V08 A; 5B5T A; 5IFO A; 1MIW A; 1BKE A; 1GNJ A; 1NT2 B; 2BXL A; 4J2V A; 1UOR A; 3WHQ A; 1MUH A; 2BXQ A; 4EMX A; 3SQJ A; 1VFI A; 4IW1 A; 5GIO A; 3B9L A; 4OT2 A; 1E7F A; 4NAW B; 1VZS A; 1MIV A; 2VUF A; 4Z69 A; 5IJF A; 1HK3 A; 1AO6 A; 2QHB A; 2BXG A; 2DBW A; 4PO0 A; 4C31 B; 1KDX A; 2XSI A; 1BJ5 A; 3NVM A; 2LQI A; 3VQI A; 5IIH A; 2EFD A; 5DQF A; 3TDL A; 2EFC A; 5IJE A; 2DYM A; 2I2Z A; 4DHX B; 2XW1 A; 3MHS B; 1IJG A; 3H3A A; 4TQ0 A; 1HK1 A; 2KBZ A; 4F5U A; 3KIK A; 1N5U A; 3WHS A; 3FWB C; 4ZBQ A; 2AJE A; 3MHH B; 2K0N A; 3A73 A; 3LU7 A; 4LB2 A; 3GQX A; 4TQ1 A; 5IIU A; 5HOZ A; 2CKX A; 2JUH A; 4GDK B; 4LB9 A; 1O9X A; 2E0X A; 2E0Y A; 2XVV A; 2BXE A; 5BPK A; 2DG5 A; 1GNI A; 3LU8 A; 4IW2 A; 4DM0 A; 1LOT A; 3H37 A; 4FIP B; 4G03 A; 1E7E A; 1TXU A; 2XVU A; 4F5V A; 2EFE A; 2GUT A; 4Z9O A; 2DBX A; 3WHR A; 5ID9 A; 4M70 B; 2AGH B; 3FNM A; 1MM8 A; 1E7H A; 2LQH A; 3SIU B; 2DBU A; 3A75 A; 1MIY A; 4L8U A; 4F5T A; 2VDB A; 4GG2 A; 3W1S A; 2BXO A; 4I9O A; 3ECP A; 1HK5 A; 3UIV A; 3KJL A; 4G01 A; 2Z8J A; 4LA0 A; 5D7G A; 4OTU A; 2QM6 A; 1JNB A; 1H9Z A; 2BXK A; 1LNS A; 3FWC C; 3G9K D; 4F5S A; 1FOU A; 3GQU A; 1H5W A; 4K71 A; 4ZCG A; 3NMU A; 3NVI A; 4OTT A; 1E7I A; 2BXN A; 3V03 A; 5GIP A; 2BXH A; 4N0F D; 4ZBK A; 2BXD A; 1J78 A; 5GHK A; 4LUF A; 2DYO A; 2BX8 A; 3CX9 A; 4WA6 B; 1E7A A; 4OR0 A; 3SIV B; 4E99 A; 1J7E A; 2ROH A; 3BPJ A; 2VUE A; 3M99 C; 4GDX A; 2BXA A; 5DBY A; 1TF0 A; 4D7X A; 2XVQ A; 5IJ5 A; 4LUH A; 2YDF A; 2OZB B; 4S1Y A; 2LXS A; 4FK5 B; 2EFH A; 5ID7 A; 2BXI A; 2I30 A; 2OT3 A; 4HGM B; 1E7G A; #chains in the Genus database with same CATH homology 2BXP A; 4ZC6 A; 1E7C A; 4N3Z A; 2XVW A; 3ICX A; 2BXB A; 4L9Q A; 2XW0 A; 3V09 A; 4W4U B; 1KW2 A; 1E7B A; 4BY9 C; 1E78 A; 1KXP D; 2QMC A; 3NVK A; 5FUO A; 4K2C A; 2Z8K A; 3JQZ A; 5GIN A; 1HA2 A; 4HGK A; 2NNW A; 2LOQ A; 1HK4 A; 4L9K A; 2NQO A; 4BKE A; 1MA9 A; 1BM0 A; 3LU6 A; 3B9M A; 4FJC B; 4JK4 A; 4G04 A; 4MBE C; 4N0U D; 3PLA A; 2BXM A; 2XMO A; 2V36 A; 2BXF A; 3GA9 L; 4GDL B; 5IIX A; 2BXC A; 1HK2 A; 2Z8I A; 4ZBR A; 4ZUX V; 3JRY A; 3V08 A; 5B5T A; 5IFO A; 1MIW A; 1BKE A; 1GNJ A; 1NT2 B; 2BXL A; 4J2V A; 1UOR A; 3WHQ A; 2BXQ A; 4EMX A; 3SQJ A; 1VFI A; 4IW1 A; 5GIO A; 3B9L A; 4OT2 A; 1E7F A; 4NAW B; 1VZS A; 1MIV A; 2VUF A; 4Z69 A; 5IJF A; 1HK3 A; 1AO6 A; 2QHB A; 2BXG A; 2DBW A; 4PO0 A; 4C31 B; 2XSI A; 1BJ5 A; 3NVM A; 3VQI A; 5IIH A; 2EFD A; 5DQF A; 3TDL A; 2EFC A; 5IJE A; 2DYM A; 2I2Z A; 4DHX B; 2XW1 A; 3MHS B; 1IJG A; 3H3A A; 4TQ0 A; 1HK1 A; 2KBZ A; 4F5U A; 3KIK A; 1N5U A; 3WHS A; 3FWB C; 4ZBQ A; 2AJE A; 3MHH B; 3A73 A; 3LU7 A; 4LB2 A; 3GQX A; 4TQ1 A; 5IIU A; 5HOZ A; 2CKX A; 2JUH A; 4GDK B; 4LB9 A; 1O9X A; 2E0X A; 2E0Y A; 2XVV A; 2BXE A; 5BPK A; 2DG5 A; 1GNI A; 3LU8 A; 4IW2 A; 1LOT A; 3H37 A; 4FIP B; 4G03 A; 1E7E A; 1TXU A; 2XVU A; 4F5V A; 2EFE A; 4Z9O A; 2DBX A; 3WHR A; 5ID9 A; 4M70 B; 3FNM A; 1E7H A; 3SIU B; 2DBU A; 3A75 A; 1MIY A; 4L8U A; 4F5T A; 2VDB A; 4GG2 A; 3W1S A; 2BXO A; 1HK5 A; 3UIV A; 3KJL A; 4G01 A; 2Z8J A; 4LA0 A; 5D7G A; 4OTU A; 2QM6 A; 1JNB A; 1H9Z A; 2BXK A; 1LNS A; 3FWC C; 3G9K D; 4F5S A; 1FOU A; 3GQU A; 1H5W A; 4K71 A; 4ZCG A; 3NMU A; 3NVI A; 4OTT A; 1E7I A; 2BXN A; 3V03 A; 5GIP A; 2BXH A; 4N0F D; 4ZBK A; 2BXD A; 1J78 A; 5GHK A; 4LUF A; 2DYO A; 2BX8 A; 3CX9 A; 4WA6 B; 1E7A A; 4OR0 A; 3SIV B; 4E99 A; 1J7E A; 2ROH A; 2VUE A; 3M99 C; 4GDX A; 2BXA A; 5DBY A; 1TF0 A; 2XVQ A; 5IJ5 A; 4LUH A; 2YDF A; 2OZB B; 4S1Y A; 4FK5 B; 2EFH A; 5ID7 A; 2BXI A; 2I30 A; 2OT3 A; 4HGM B; 1E7G A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
