5CHZA

Structure of wild-type human mbd4 bound to a g:t mismatch
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
140
structure length
140
Chain Sequence
WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/dna
source organism Homo sapiens
publication title Structure of wild-type human MBD4 bound to a G:T mismatch
rcsb
molecule keywords Methyl-CpG-binding domain protein 4
total genus 47
structure length 140
sequence length 140
ec nomenclature ec 3.2.2.-:
pdb deposition date 2015-07-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 5chzA00
1KEAA 1MPGA 1VRLA 4B22A 4E9GA 3D4VA 1RRQA 4E9EA 2NOEA 4EW4A 3CVSA 1YQRA 2NOIA 2NOFA 1XG7A 1ORPA 1YQKA 1HU0A 4UOBA 4OFEA 2ABKA 3OH9A 5KN9A 1WEGA 4DK9A 3N5NX 3KNTA 1KG3A 4YPRA 4EVVA 3I0WA 1PU8A 1KG5A 1LWWA 1M3QA 1KG7A 5CHZA 1P7MA 1DIZA 3CWSA 1LWYA 3CWTA 4E9FA 3FSPA 2NOBA 4OFHA 4EJZA 3OGDA 4YPHA 1RRSA 1KO9A 1WEIA 1LWVA 4UNFA 1XQOA 4B24A 2JHNA 3IHOA 1MUNA 1KG6A 1N39A 3IH7A 4B23A 3CWUA 2JG6A 4EJYA 3CWAA 1NGNA 4AI4A 3CVTA 1LMZA 4EA4A 4OFAA 1YQLA 1N3AA 1YQMA 3S6IA 2OFIA 3CW7A 4B21A 5DPKA 3KTUA 2I5WA 3F0ZA 1ORNA 1KQJA 4EA5A 1PU6A 3F10A 1PU7A 1XQPA 4YOQA 2YG9A 4AIAA 1N3CA 3FHFA 4HSBA 2NOLA 5AN4A 1PVSA 3OH6A 1M3HA 1KG2A 2NOHA 3FHGA 1P59A 3I0XA 4EW0A 1MUDA 5KN8A 1NKUA 1EBMA 1WEFA 3G0QA 1MUYA 2NOZA 3N0UA 2YG8A 2OFKA 2JHJA 4E9HA 1FN7A 2XHIA 4PIIA 1KG4A 2H56A 4AI5A
chains in the Genus database with same CATH superfamily
1KEAA 1MPGA 4BE2A 1VRLA 3OYJA 4B22A 4E9GA 3L2RA 3D4VA 1RRQA 2JPSA 4E9EA 2NOEA 4EW4A 3CVSA 1YQRA 2NOIA 2NOFA 1XG7A 1ORPA 1YQKA 2W04A 1HU0A 4UOBA 4OFEA 3OYNA 2ABKA 3OH9A 5KN9A 1WEGA 4DK9A 3N5NX 2V75A 3KNTA 3LCNA 3OYFA 1KG3A 4YPRA 4EVVA 3I0WA 4E7HA 1PU8A 1KG5A 3OYMA 1LWWA 1M3QA 5FROA 1KG7A 5CHZA 1P7MA 1DIZA 3CWSA 1LWYA 3CWTA 4E9FA 3FSPA 2NOBA 4OFHA 3OYCA 4EJZA 4ZTJA 3OGDA 4BACA 4YPHA 3L2VA 1RRSA 1KO9A 1WEIA 1LWVA 4E7KA 5FRNA 3OYEA 4UNFA 4ZTFA 4E7LA 3R2XC 1XQOA 4B24A 2JHNA 3OS2A 3IHOA 1MUNA 1KG6A 1N39A 3IH7A 4B23A 3CWUA 4BE0A 2JG6A 4EJYA 3CWAA 1NGNA 4AI4A 3CVTA 1LMZA 4EA4A 4OFAA 3VW4A 1YQLA 1N3AA 4BE1A 1YQMA 3S6IA 2OFIA 3NNQA 4BDZA 3CW7A 4B21A 5DPKA 3OYBA 3KTUA 3OYHA 2I5WA 3F0ZA 1ORNA 1KQJA 4EA5A 3OS0A 3OYDA 3S3MA 1PU6A 3F10A 1PU7A 1XQPA 4NZGA 5FRMA 4YOQA 2YG9A 4AIAA 1N3CA 3FHFA 4HSBA 4E7JA 2NOLA 3OYGA 5AN4A 1PVSA 3OH6A 1M3HA 1KG2A 2NOHA 4IKFA 3FHGA 1P59A 3I0XA 4EW0A 3OYAA 3OS1A 1MUDA 3OYLA 3S3NA 3L2WA 5KN8A 1NKUA 1EBMA 1WEFA 3L2UA 3G0QA 1MUYA 2NOZA 4BDYA 3OY9A 3S3OA 3N0UA 3L2QA 2YG8A 2OFKA 2JHJA 4E9HA 1FN7A 4E7IA 2XHIA 3OYIA 4PIIA 2W03A 1KG4A 3OYKA 1U84A 2H56A 4AI5A
chains in the Genus database with same CATH topology
1KEAA 1MPGA 1VRLA 4B22A 4E9GA 3D4VA 1RRQA 4E9EA 2NOEA 4EW4A 3CVSA 1YQRA 2NOIA 2NOFA 1XG7A 1ORPA 1YQKA 1HU0A 4UOBA 4OFEA 2ABKA 3OH9A 5KN9A 1WEGA 4DK9A 3N5NX 3KNTA 1KG3A 4YPRA 4EVVA 3I0WA 1PU8A 1KG5A 1LWWA 1M3QA 1KG7A 5CHZA 1P7MA 1DIZA 3CWSA 1LWYA 3CWTA 4E9FA 3FSPA 2NOBA 4OFHA 4EJZA 3OGDA 4YPHA 1RRSA 1KO9A 1WEIA 1LWVA 4UNFA 1XQOA 4B24A 2JHNA 3IHOA 1MUNA 1KG6A 1N39A 3IH7A 4B23A 3CWUA 2JG6A 4EJYA 3CWAA 1NGNA 4AI4A 3CVTA 1LMZA 4EA4A 4OFAA 1YQLA 1N3AA 1YQMA 3S6IA 2OFIA 3CW7A 4B21A 5DPKA 3KTUA 2I5WA 3F0ZA 1ORNA 1KQJA 4EA5A 1PU6A 3F10A 1PU7A 1XQPA 4YOQA 2YG9A 4AIAA 1N3CA 3FHFA 4HSBA 2NOLA 5AN4A 1PVSA 3OH6A 1M3HA 1KG2A 2NOHA 3FHGA 1P59A 3I0XA 4EW0A 1MUDA 5KN8A 1NKUA 1EBMA 1WEFA 3G0QA 1MUYA 2NOZA 3N0UA 2YG8A 2OFKA 2JHJA 4E9HA 1FN7A 2XHIA 4PIIA 1KG4A 2H56A 4AI5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KEA A;  1MPG A;  1VRL A;  4B22 A;  4E9G A;  3D4V A;  1RRQ A;  4E9E A;  2NOE A;  4EW4 A;  3CVS A;  1YQR A;  2NOI A;  2NOF A;  1XG7 A;  1ORP A;  1YQK A;  1HU0 A;  4UOB A;  4OFE A;  2ABK A;  3OH9 A;  5KN9 A;  1WEG A;  4DK9 A;  3N5N X;  3KNT A;  1KG3 A;  4YPR A;  4EVV A;  3I0W A;  1PU8 A;  1KG5 A;  1LWW A;  1M3Q A;  1KG7 A;  5CHZ A;  1P7M A;  1DIZ A;  3CWS A;  1LWY A;  3CWT A;  4E9F A;  3FSP A;  2NOB A;  4OFH A;  4EJZ A;  3OGD A;  4YPH A;  1RRS A;  1KO9 A;  1WEI A;  1LWV A;  4UNF A;  1XQO A;  4B24 A;  2JHN A;  3IHO A;  1MUN A;  1KG6 A;  1N39 A;  3IH7 A;  4B23 A;  3CWU A;  2JG6 A;  4EJY A;  3CWA A;  1NGN A;  4AI4 A;  3CVT A;  1LMZ A;  4EA4 A;  4OFA A;  1YQL A;  1N3A A;  1YQM A;  3S6I A;  2OFI A;  3CW7 A;  4B21 A;  5DPK A;  3KTU A;  2I5W A;  3F0Z A;  1ORN A;  1KQJ A;  4EA5 A;  1PU6 A;  3F10 A;  1PU7 A;  1XQP A;  4YOQ A;  2YG9 A;  4AIA A;  1N3C A;  3FHF A;  4HSB A;  2NOL A;  5AN4 A;  1PVS A;  3OH6 A;  1M3H A;  1KG2 A;  2NOH A;  3FHG A;  1P59 A;  3I0X A;  4EW0 A;  1MUD A;  5KN8 A;  1NKU A;  1EBM A;  1WEF A;  3G0Q A;  1MUY A;  2NOZ A;  3N0U A;  2YG8 A;  2OFK A;  2JHJ A;  4E9H A;  1FN7 A;  2XHI A;  4PII A;  1KG4 A;  2H56 A;  4AI5 A; 
#chains in the Genus database with same CATH topology
 1KEA A;  1MPG A;  4BE2 A;  1VRL A;  3OYJ A;  4B22 A;  4E9G A;  3L2R A;  3D4V A;  1RRQ A;  2JPS A;  4E9E A;  2NOE A;  4EW4 A;  3CVS A;  1YQR A;  2NOI A;  2NOF A;  1XG7 A;  1ORP A;  1YQK A;  2W04 A;  1HU0 A;  4UOB A;  4OFE A;  3OYN A;  2ABK A;  3OH9 A;  5KN9 A;  1WEG A;  4DK9 A;  3N5N X;  2V75 A;  3KNT A;  3LCN A;  3OYF A;  1KG3 A;  4YPR A;  4EVV A;  3I0W A;  4E7H A;  1PU8 A;  1KG5 A;  3OYM A;  1LWW A;  1M3Q A;  5FRO A;  1KG7 A;  5CHZ A;  1P7M A;  1DIZ A;  3CWS A;  1LWY A;  3CWT A;  4E9F A;  3FSP A;  2NOB A;  4OFH A;  3OYC A;  4EJZ A;  4ZTJ A;  3OGD A;  4BAC A;  4YPH A;  3L2V A;  1RRS A;  1KO9 A;  1WEI A;  1LWV A;  4E7K A;  5FRN A;  3OYE A;  4UNF A;  4ZTF A;  4E7L A;  3R2X C;  1XQO A;  4B24 A;  2JHN A;  3OS2 A;  3IHO A;  1MUN A;  1KG6 A;  1N39 A;  3IH7 A;  4B23 A;  3CWU A;  4BE0 A;  2JG6 A;  4EJY A;  3CWA A;  1NGN A;  4AI4 A;  3CVT A;  1LMZ A;  4EA4 A;  4OFA A;  3VW4 A;  1YQL A;  1N3A A;  4BE1 A;  1YQM A;  3S6I A;  2OFI A;  3NNQ A;  4BDZ A;  3CW7 A;  4B21 A;  5DPK A;  3OYB A;  3KTU A;  3OYH A;  2I5W A;  3F0Z A;  1ORN A;  1KQJ A;  4EA5 A;  3OS0 A;  3OYD A;  3S3M A;  1PU6 A;  3F10 A;  1PU7 A;  1XQP A;  4NZG A;  5FRM A;  4YOQ A;  2YG9 A;  4AIA A;  1N3C A;  3FHF A;  4HSB A;  4E7J A;  2NOL A;  3OYG A;  5AN4 A;  1PVS A;  3OH6 A;  1M3H A;  1KG2 A;  2NOH A;  4IKF A;  3FHG A;  1P59 A;  3I0X A;  4EW0 A;  3OYA A;  3OS1 A;  1MUD A;  3OYL A;  3S3N A;  3L2W A;  5KN8 A;  1NKU A;  1EBM A;  1WEF A;  3L2U A;  3G0Q A;  1MUY A;  2NOZ A;  4BDY A;  3OY9 A;  3S3O A;  3N0U A;  3L2Q A;  2YG8 A;  2OFK A;  2JHJ A;  4E9H A;  1FN7 A;  4E7I A;  2XHI A;  3OYI A;  4PII A;  2W03 A;  1KG4 A;  3OYK A;  1U84 A;  2H56 A;  4AI5 A; 
#chains in the Genus database with same CATH homology
 1KEA A;  1MPG A;  1VRL A;  4B22 A;  4E9G A;  3D4V A;  1RRQ A;  4E9E A;  2NOE A;  4EW4 A;  3CVS A;  1YQR A;  2NOI A;  2NOF A;  1XG7 A;  1ORP A;  1YQK A;  1HU0 A;  4UOB A;  4OFE A;  2ABK A;  3OH9 A;  5KN9 A;  1WEG A;  4DK9 A;  3N5N X;  3KNT A;  1KG3 A;  4YPR A;  4EVV A;  3I0W A;  1PU8 A;  1KG5 A;  1LWW A;  1M3Q A;  1KG7 A;  5CHZ A;  1P7M A;  1DIZ A;  3CWS A;  1LWY A;  3CWT A;  4E9F A;  3FSP A;  2NOB A;  4OFH A;  4EJZ A;  3OGD A;  4YPH A;  1RRS A;  1KO9 A;  1WEI A;  1LWV A;  4UNF A;  1XQO A;  4B24 A;  2JHN A;  3IHO A;  1MUN A;  1KG6 A;  1N39 A;  3IH7 A;  4B23 A;  3CWU A;  2JG6 A;  4EJY A;  3CWA A;  1NGN A;  4AI4 A;  3CVT A;  1LMZ A;  4EA4 A;  4OFA A;  1YQL A;  1N3A A;  1YQM A;  3S6I A;  2OFI A;  3CW7 A;  4B21 A;  5DPK A;  3KTU A;  2I5W A;  3F0Z A;  1ORN A;  1KQJ A;  4EA5 A;  1PU6 A;  3F10 A;  1PU7 A;  1XQP A;  4YOQ A;  2YG9 A;  4AIA A;  1N3C A;  3FHF A;  4HSB A;  2NOL A;  5AN4 A;  1PVS A;  3OH6 A;  1M3H A;  1KG2 A;  2NOH A;  3FHG A;  1P59 A;  3I0X A;  4EW0 A;  1MUD A;  5KN8 A;  1NKU A;  1EBM A;  1WEF A;  3G0Q A;  1MUY A;  2NOZ A;  3N0U A;  2YG8 A;  2OFK A;  2JHJ A;  4E9H A;  1FN7 A;  2XHI A;  4PII A;  1KG4 A;  2H56 A;  4AI5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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